LOCUS       DAVLTT010000001        86360 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLTT010000001 DAVLTT010000000
VERSION     DAVLTT010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 86360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86360
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.001"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            221..568
                     /locus_tag="VYN15_000001"
     CDS             221..568
                     /locus_tag="VYN15_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1451419.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(847..1683)
                     /locus_tag="VYN15_000002"
     CDS             complement(847..1683)
                     /locus_tag="VYN15_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1451420.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(1696..2325)
                     /locus_tag="VYN15_000003"
     CDS             complement(1696..2325)
                     /locus_tag="VYN15_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1451421.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(2335..2976)
                     /locus_tag="VYN15_000004"
     CDS             complement(2335..2976)
                     /locus_tag="VYN15_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1451422.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(3122..4351)
                     /locus_tag="VYN15_000005"
     CDS             complement(3122..4351)
                     /locus_tag="VYN15_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV1451423.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSNLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(4341..5507)
                     /locus_tag="VYN15_000006"
     CDS             complement(4341..5507)
                     /locus_tag="VYN15_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1451424.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            5651..6664
                     /locus_tag="VYN15_000007"
     CDS             5651..6664
                     /locus_tag="VYN15_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV1451425.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQLISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(6709..7128)
                     /locus_tag="VYN15_000008"
     CDS             complement(6709..7128)
                     /locus_tag="VYN15_000008"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV1451426.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(7139..8545)
                     /gene="atpD"
                     /locus_tag="VYN15_000009"
     CDS             complement(7139..8545)
                     /gene="atpD"
                     /locus_tag="VYN15_000009"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV1451427.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(8631..9509)
                     /locus_tag="VYN15_000010"
     CDS             complement(8631..9509)
                     /locus_tag="VYN15_000010"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV1451428.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(9525..11030)
                     /locus_tag="VYN15_000011"
     CDS             complement(9525..11030)
                     /locus_tag="VYN15_000011"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV1451429.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(11045..11581)
                     /locus_tag="VYN15_000012"
     CDS             complement(11045..11581)
                     /locus_tag="VYN15_000012"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV1451430.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(11581..12075)
                     /gene="atpF"
                     /locus_tag="VYN15_000013"
     CDS             complement(11581..12075)
                     /gene="atpF"
                     /locus_tag="VYN15_000013"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV1451431.1"
                     /translation="MHVTVGELIGNFVLITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(12089..12805)
                     /gene="atpB"
                     /locus_tag="VYN15_000014"
     CDS             complement(12089..12805)
                     /gene="atpB"
                     /locus_tag="VYN15_000014"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV1451432.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(12840..13040)
                     /locus_tag="VYN15_000015"
     CDS             complement(12840..13040)
                     /locus_tag="VYN15_000015"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV1451433.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(13115..14122)
                     /locus_tag="VYN15_000016"
                     /pseudo
     CDS             complement(13115..14122)
                     /locus_tag="VYN15_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(14543..14941)
                     /locus_tag="VYN15_000017"
     CDS             complement(14543..14941)
                     /locus_tag="VYN15_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1451434.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            complement(15314..15796)
                     /gene="greA"
                     /locus_tag="VYN15_000018"
     CDS             complement(15314..15796)
                     /gene="greA"
                     /locus_tag="VYN15_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV1451435.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(15867..17522)
                     /gene="mltG"
                     /locus_tag="VYN15_000019"
     CDS             complement(15867..17522)
                     /gene="mltG"
                     /locus_tag="VYN15_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV1451436.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(17603..18097)
                     /locus_tag="VYN15_000020"
     CDS             complement(17603..18097)
                     /locus_tag="VYN15_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1451437.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(18094..18558)
                     /locus_tag="VYN15_000021"
     CDS             complement(18094..18558)
                     /locus_tag="VYN15_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1451438.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDCKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(18568..19902)
                     /locus_tag="VYN15_000022"
     CDS             complement(18568..19902)
                     /locus_tag="VYN15_000022"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV1451439.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(19913..20530)
                     /locus_tag="VYN15_000023"
     CDS             complement(19913..20530)
                     /locus_tag="VYN15_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1451440.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(20578..23676)
                     /locus_tag="VYN15_000024"
     CDS             complement(20578..23676)
                     /locus_tag="VYN15_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1451441.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLIFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVDRQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAIQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILADNHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(23769..24935)
                     /locus_tag="VYN15_000025"
     CDS             complement(23769..24935)
                     /locus_tag="VYN15_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1451442.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IHQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            complement(24943..26037)
                     /locus_tag="VYN15_000026"
     CDS             complement(24943..26037)
                     /locus_tag="VYN15_000026"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1451443.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(26195..27877)
                     /locus_tag="VYN15_000027"
     CDS             complement(26195..27877)
                     /locus_tag="VYN15_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451444.1"
                     /translation="MKLKLLRVDTKVIMGSFFLVLSSLLALLPPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQTLFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTIYSSSKGSSVALENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENR
                     PVLKDITCSIFKGQKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKE
                     WRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDT
                     EVGERGRLLSGGRSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEK
                     TVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            complement(28049..30007)
                     /locus_tag="VYN15_000028"
     CDS             complement(28049..30007)
                     /locus_tag="VYN15_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1451445.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(30210..31832)
                     /locus_tag="VYN15_000029"
     CDS             complement(30210..31832)
                     /locus_tag="VYN15_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1451446.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSLFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            31938..33383
                     /locus_tag="VYN15_000030"
     CDS             31938..33383
                     /locus_tag="VYN15_000030"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV1451447.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYIAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISLDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FRFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(33429..33623)
                     /locus_tag="VYN15_000031"
     CDS             complement(33429..33623)
                     /locus_tag="VYN15_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1451448.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(33724..34332)
                     /locus_tag="VYN15_000032"
     CDS             complement(33724..34332)
                     /locus_tag="VYN15_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV1451449.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            complement(34357..34869)
                     /locus_tag="VYN15_000033"
     CDS             complement(34357..34869)
                     /locus_tag="VYN15_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV1451450.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAAFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(34955..35890)
                     /locus_tag="VYN15_000034"
     CDS             complement(34955..35890)
                     /locus_tag="VYN15_000034"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV1451451.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(35961..36260)
                     /locus_tag="VYN15_000035"
     CDS             complement(35961..36260)
                     /locus_tag="VYN15_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV1451452.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(36250..36999)
                     /locus_tag="VYN15_000036"
     CDS             complement(36250..36999)
                     /locus_tag="VYN15_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV1451453.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(37053..37412)
                     /locus_tag="VYN15_000037"
     CDS             complement(37053..37412)
                     /locus_tag="VYN15_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV1451454.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKTK"
     gene            complement(37414..38814)
                     /locus_tag="VYN15_000038"
     CDS             complement(37414..38814)
                     /locus_tag="VYN15_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV1451455.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(39109..39348)
                     /locus_tag="VYN15_000039"
     CDS             complement(39109..39348)
                     /locus_tag="VYN15_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV1451456.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(39380..39850)
                     /gene="ssbA"
                     /locus_tag="VYN15_000040"
     CDS             complement(39380..39850)
                     /gene="ssbA"
                     /locus_tag="VYN15_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV1451457.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(39862..40152)
                     /locus_tag="VYN15_000041"
     CDS             complement(39862..40152)
                     /locus_tag="VYN15_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV1451458.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(40305..41651)
                     /gene="asnS"
                     /locus_tag="VYN15_000042"
     CDS             complement(40305..41651)
                     /gene="asnS"
                     /locus_tag="VYN15_000042"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV1451459.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGIKHIREAIPFPRMLHRIKP"
     gene            complement(41667..42032)
                     /locus_tag="VYN15_000043"
     CDS             complement(41667..42032)
                     /locus_tag="VYN15_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1451460.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLVPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGIEASGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(42025..43212)
                     /locus_tag="VYN15_000044"
     CDS             complement(42025..43212)
                     /locus_tag="VYN15_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1451461.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYSFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(43209..43697)
                     /locus_tag="VYN15_000045"
     CDS             complement(43209..43697)
                     /locus_tag="VYN15_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV1451462.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            44018..44566
                     /locus_tag="VYN15_000046"
     CDS             44018..44566
                     /locus_tag="VYN15_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1451463.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            complement(44804..50752)
                     /locus_tag="VYN15_000047"
     CDS             complement(44804..50752)
                     /locus_tag="VYN15_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1451464.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAASVLLGTALVLGVAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTEEV
                     TKPAEKVEEAKDKKEEVTHQDAVDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADATEAELSAAESSIQSFIIGLELRSNSNKETVSETPVAKKADAVESKEGAK
                     PAATTERSAVDSAILPTSTADKVETTSAPASINEILKLGLSLSDARQNPAIRKENVNR
                     GYSGFRAASNPANPIVSGSGNTVAFADISQGGRSYSFRGYGNSRGGNSIHYDVTTVRS
                     GNSVNFTISYSAPGDSREFVNNNFILDKGDGFGNPSNATITSSNPRVREQSKSISQGA
                     NYVSHSGYSMTSAISTNTEQTIRFSLPIINLNGDLSVRLKPVTFNVDQGGGGAATSND
                     PYSNSNYYYRANPLYLDANPYGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEK
                     GQRQITYKVHRFGNETLLGLPISNSVTKEAKPRIMQIGVAKDLIDTVKPRVDQNKVGD
                     TNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGAQGAKGEKGDR
                     GERGLTGAQGAKGEKGAQGERGLTGAKGEKGDQGERGLTGAQGEKGDRGERGLTGAKG
                     EKGAQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTVVRDGFDGASPLVATQ
                     RNDADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKGDKGEQGLQGRDGAQG
                     PKGADGQRGPAGPQGPKGEQGNPGTPGKDGKSLIAVKNGTETKVYVEDPARPGQPLNP
                     NQPLATITDGRNGTNGQSPTITATRSVQNGKNGVLVTITPVGGRPQTTFVEDGQKGAD
                     GKTPTVTITEGQNGTHTLTVHNPGSPDVTTTIRDGATGQAGRDGKDVLNGKVNPQPNQ
                     GKNGDKYINTETGDVYVKNNGNWDKEGNIKGPKGDKGADGAKGEKGDQGERGLTGAQG
                     AKGADGAVGRDGRDGKDVLNGKANPEAHQGKDGDKYVNTETGDVFVKNNGNWDKEGNI
                     KGPKGDKGERGEDGKTPEVTVTPGKDGHSTDITFTVPGKDPVTVNVKDGENGLNGKTP
                     KVDLLRVQGKNGNPSHTIVTFYTDENNDGKYTPGTDELLGSEMIKDGAKGADGRDGKS
                     LLTVKDGKETKVYQEDPANPGQPLNPEKPLAVIRDGVDGKSPTVTAVRKDEAGHKGVE
                     ITVDNHDGSQPTTVFVQDGAKGKTGATGQDGQTPTITTQRGQDGQSTVVTITTSGKDP
                     VTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRDTDAAATPTRNGIRVTVYDDVNDNGV
                     YDEGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTHTITVQNPDGSESTTVVKDGK
                     DGKTANITTTENPDGSHTITVTNPDGSTKETVVKNGKDGKTPKVEVTDNNDGTHTVKV
                     TDGDGNVTNAIIKDGKDGKAATATTTENPDGSHTVTITNPDGTKNEFVVKNGRDGVDG
                     RTPTASVRDNGDGSHTIVITNPEGVTTETTVRDGKSPKVTITDEQNGTHKISVLNGDG
                     TTTETIIKDGKSPVATVRDNQDGTYTIRVENGNGTVSETTVRDGKSPTAKVVDNGDGT
                     HTITVVNSDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVTGADGKGTTTTIFDGKSPK
                     ANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPTVTVKNNNDGTHVVTITNP
                     DGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGTVTKTVIKDGKDGRDGRDG
                     RDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVKPVPAQPTPNVPTPEVPVQ
                     PTPAVSTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVAPTTGKENRGDKLPETGSQ
                     SDYISVLLGSGILLSLYVGRRKED"
     gene            50968..52452
                     /locus_tag="VYN15_000048"
     CDS             50968..52452
                     /locus_tag="VYN15_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1451465.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILELLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            complement(52503..53231)
                     /gene="yaaA"
                     /locus_tag="VYN15_000049"
     CDS             complement(52503..53231)
                     /gene="yaaA"
                     /locus_tag="VYN15_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV1451466.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(53310..53474)
                     /locus_tag="VYN15_000050"
     CDS             complement(53310..53474)
                     /locus_tag="VYN15_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV1451467.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            complement(53540..55135)
                     /locus_tag="VYN15_000051"
     CDS             complement(53540..55135)
                     /locus_tag="VYN15_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451468.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            complement(55147..55557)
                     /locus_tag="VYN15_000052"
     CDS             complement(55147..55557)
                     /locus_tag="VYN15_000052"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1451469.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(55673..56464)
                     /gene="yghU"
                     /locus_tag="VYN15_000053"
     CDS             complement(55673..56464)
                     /gene="yghU"
                     /locus_tag="VYN15_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV1451470.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(56477..59173)
                     /locus_tag="VYN15_000054"
     CDS             complement(56477..59173)
                     /locus_tag="VYN15_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV1451471.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            59477..60661
                     /gene="mntE"
                     /locus_tag="VYN15_000055"
     CDS             59477..60661
                     /gene="mntE"
                     /locus_tag="VYN15_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV1451472.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREESVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(60804..62675)
                     /locus_tag="VYN15_000056"
     CDS             complement(60804..62675)
                     /locus_tag="VYN15_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1451473.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLFLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKKVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(62672..63856)
                     /locus_tag="VYN15_000057"
     CDS             complement(62672..63856)
                     /locus_tag="VYN15_000057"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV1451474.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHNPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLCQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            complement(63868..64635)
                     /locus_tag="VYN15_000058"
     CDS             complement(63868..64635)
                     /locus_tag="VYN15_000058"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV1451475.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTAPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(64912..65760)
                     /locus_tag="VYN15_000059"
     CDS             complement(64912..65760)
                     /locus_tag="VYN15_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1451476.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(65762..66136)
                     /locus_tag="VYN15_000060"
     CDS             complement(65762..66136)
                     /locus_tag="VYN15_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV1451477.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(66210..67562)
                     /locus_tag="VYN15_000061"
     CDS             complement(66210..67562)
                     /locus_tag="VYN15_000061"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV1451478.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            complement(67586..68365)
                     /locus_tag="VYN15_000062"
     CDS             complement(67586..68365)
                     /locus_tag="VYN15_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV1451479.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(68352..69209)
                     /locus_tag="VYN15_000063"
     CDS             complement(68352..69209)
                     /locus_tag="VYN15_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV1451480.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            69345..70313
                     /locus_tag="VYN15_000064"
     CDS             69345..70313
                     /locus_tag="VYN15_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1451481.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEDYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGDGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(70347..71258)
                     /gene="whiA"
                     /locus_tag="VYN15_000065"
     CDS             complement(70347..71258)
                     /gene="whiA"
                     /locus_tag="VYN15_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV1451482.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(71255..72232)
                     /locus_tag="VYN15_000066"
     CDS             complement(71255..72232)
                     /locus_tag="VYN15_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV1451483.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSNHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(72229..73119)
                     /gene="rapZ"
                     /locus_tag="VYN15_000067"
     CDS             complement(72229..73119)
                     /gene="rapZ"
                     /locus_tag="VYN15_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV1451484.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(73171..73551)
                     /locus_tag="VYN15_000068"
     CDS             complement(73171..73551)
                     /locus_tag="VYN15_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV1451485.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(73562..74149)
                     /locus_tag="VYN15_000069"
     CDS             complement(73562..74149)
                     /locus_tag="VYN15_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV1451486.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(74158..75390)
                     /gene="clpX"
                     /locus_tag="VYN15_000070"
     CDS             complement(74158..75390)
                     /gene="clpX"
                     /locus_tag="VYN15_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV1451487.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(75422..75592)
                     /locus_tag="VYN15_000071"
     CDS             complement(75422..75592)
                     /locus_tag="VYN15_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451488.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            complement(75592..76098)
                     /locus_tag="VYN15_000072"
     CDS             complement(75592..76098)
                     /locus_tag="VYN15_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV1451489.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(76228..76746)
                     /locus_tag="VYN15_000073"
     CDS             complement(76228..76746)
                     /locus_tag="VYN15_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV1451490.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            complement(77242..78747)
                     /gene="lytC"
                     /locus_tag="VYN15_000074"
     CDS             complement(77242..78747)
                     /gene="lytC"
                     /locus_tag="VYN15_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV1451491.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            complement(78785..79543)
                     /locus_tag="VYN15_000075"
     CDS             complement(78785..79543)
                     /locus_tag="VYN15_000075"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV1451492.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            complement(79641..80318)
                     /locus_tag="VYN15_000076"
     CDS             complement(79641..80318)
                     /locus_tag="VYN15_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV1451493.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            complement(80327..81271)
                     /locus_tag="VYN15_000077"
     CDS             complement(80327..81271)
                     /locus_tag="VYN15_000077"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV1451494.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            complement(81453..81965)
                     /locus_tag="VYN15_000078"
     CDS             complement(81453..81965)
                     /locus_tag="VYN15_000078"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV1451495.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            complement(82053..82811)
                     /locus_tag="VYN15_000079"
     CDS             complement(82053..82811)
                     /locus_tag="VYN15_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1451496.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            83019..83165
                     /locus_tag="VYN15_000080"
     CDS             83019..83165
                     /locus_tag="VYN15_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451497.1"
                     /translation="MEIKEQTRKLAVSCSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEY"
     gene            complement(83312..84442)
                     /gene="ugpC"
                     /locus_tag="VYN15_000081"
     CDS             complement(83312..84442)
                     /gene="ugpC"
                     /locus_tag="VYN15_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV1451498.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(84725..84810)
                     /locus_tag="VYN15_000082"
     tRNA            complement(84725..84810)
                     /locus_tag="VYN15_000082"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(84774..84776),aa:Leu,seq:aag)
     gene            complement(84892..85467)
                     /locus_tag="VYN15_000083"
     CDS             complement(84892..85467)
                     /locus_tag="VYN15_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1451499.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            complement(85467..86255)
                     /gene="codY"
                     /locus_tag="VYN15_000084"
     CDS             complement(85467..86255)
                     /gene="codY"
                     /locus_tag="VYN15_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV1451500.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
BASE COUNT        24848 a        19457 c        15833 g        26222 t
ORIGIN      
        1 tctttctaat gatggttttg tcgcttttca ttataggtca tatgggactt tttttctaca
       61 caaaatagtc tccataatat ctatagggga tttacccact acaaatatta tagagcctaa
      121 aagatgagac caaccaacct catctttttt cgtatcaaat ctaagcaatt ttagaaactt
      181 tatggcatac tagacttatc aatgaaagcg aggtaatctc atggaacaat ttttagataa
      241 catcaaagac cttgaagtca ctacagttgt gcgtgcgcaa gaagctcttg ataaaaaaga
      301 aactgcaacc ttctttatcg gtcgcaaaac ttgcccttac tgccgtaaat ttgcaggtac
      361 attgtcaggt gtcgtagctg aaaccaaagc tcacatttac ttcatcaata gtgaagaacc
      421 aagccaactc aatgatttgc aagcattccg ctcacgctat ggaatcccaa ctgtaccagg
      481 ttttattcat attacagatg gacaaatcaa cgtccgttgc gactcttcaa tgtcagcaca
      541 agaaatcaaa gatttcgcag gattgtaaaa aatcagctaa caagtcttaa aatcacaaaa
      601 acgcataatg taaggtgcaa aaaccttgat attatgcgtt ttattgttcc taaaacagtt
      661 acatcagcat ttcattacag aacattttaa ttttggaagt caaatcaatt tttaacaata
      721 ttttagaaat cacagtgggc tattccatat tcaattatcc agattcaatc gctattatcg
      781 ttttcctaga ttacaaaaaa aactacgttt tgctaatcaa aacgtagtct cagccactat
      841 tttatcttac tgtccttctt ttacttcttt ggttgctaca tcttctccaa accatttttg
      901 gctgatttct tggaacttgc cgtccttgta aagactagaa aaagcttcat ttatcttctt
      961 aaccaaggtt gtatcttcct tacgggctcc aaccgcaaaa gcttctgttt ctagtccaac
     1021 tgtaaagaca ttataatcgt ttaaaacacc ttctgcttct aaataatagt ttgcatagac
     1081 acggtcaatc aatagaccat caattcgatc gtttttcaaa tcaatcaagg cttcattaaa
     1141 ggtttggtat tgattcgctt ccttattagc gacaatattc ttcaaaagtt ctggatttgc
     1201 ttcaaagtcc gcataaccag atgaaccagc ttgagctcct aatgtctttc cagtcatatc
     1261 ctttgcagtc gtgataccag atgatttctt cgtaaccaat acctgctcat tcttcatata
     1321 tgagttactg aaagccacct tttcacggcg ttcgtctgta gcggaatagc cattccaaat
     1381 cagatcaatc gttccttttg tcaattcagc ttctttcaaa tcccaatcaa tcggttgcca
     1441 atttaccgtg attccgtatt tttcaaaaac agctgtagct aaatcaatat caaatcctgc
     1501 ataagaacca tctttctgag caaatcccat tggaacaaaa gtactatcaa atccaatagt
     1561 aatagacttg ttagactggt actttgacca attatctcca ctagtttcgc tagaattttt
     1621 cccacaagct actaagaaca aagcagtcat cagactgact aatacaagca tccatttttt
     1681 catccatttt tcctcctatt taggttctac tttcaataat acatctgcga tattttcagc
     1741 aaactgcaaa tcatgggtaa ccacaatctg ggtcatccca agttccctat tttgcaagat
     1801 tagcttctcc acttccaaac gtaattctgg atccagggca gaagttggtt catcgtagcc
     1861 aatgatttct gggtcaatca tcatagcacg cgccaaagcc actcgctgct tttgcccacc
     1921 agatagtgag aaaggatagg cctctgcgtg tcctcctagt cctaactgtt ccaagagtcc
     1981 actcgccttc ttctcagcct cttcctgctt cattcccatg gtcttcacag gcgataaagt
     2041 caaattttcc agaactgata gatgaggaaa tagttgaaaa tcttggaaga caaatcccag
     2101 taggttgcgc ttctgcaatt catccagctc taaaggttgt ccattataaa agatttgccc
     2161 tgaatcaatg gtttcaagac ctgcaagcat acgtaaaaga gttgtcttac ctccaccaga
     2221 aggtccaacg atagccagga tttgcttttc aggaatactt agactgaaat tagacaggat
     2281 ttgtttgtct ccaaagactt tattgatatt tcgtaattct aacatggcag cctcctatct
     2341 ataataacta tacttcttct caactttttt ggaaataatt gtcacaatcc caatcaaaat
     2401 caaataaatg gctcctgcca agaacatagg aactagacta gcatcgcggt tagcagctgt
     2461 tcgactagcc aagataaggt ctgaaattcc gagagcatag accaaagaag tatccttgac
     2521 caaactcata acttcattaa agacactagg aagaacaatc ttggtcactt ggggcaagat
     2581 aatatagcgc actctgtcaa aagggctaaa ctttaagacc ttggcagcct catactgtcc
     2641 tcttggaata gtgtcaattc ccccacggaa aatttctgca aagtaagctg catagttgag
     2701 aacaaaggca ataatagctg caggaaggcg gtctaaacga atcccaatac ttgggagcac
     2761 ataatagata aaaatcagtt gcaagagtaa gggggttcct cgcataaccc agatgtaaat
     2821 gttaatcaga taatggaggg gcttccaatg gacttgcaag gcaaaggcaa tcaaaacgcc
     2881 caagggaatc gaaaatagca agaccagtgc aaagacctgt acagtcgtgc tcgcaccatt
     2941 cagtaaactc ggtaatatct caaataaata agacatactg cacctcctaa aagtaattgt
     3001 tcctattata gcatgaataa acaagattac caagtatttt tgtaaaaaga ttctaccata
     3061 tacaaataaa aaccgtagct atcaaaagag ataaactaca gttctatatg tttaaacatt
     3121 cttacaatct ctcaaacagt tcttgcattt gcacatcatc tggaaccagt tttaagtaag
     3181 tgtgagcatg gacttttgct tcttcaaaat gtcccaattc acgcaagaga tagatatagt
     3241 gttccagaaa ttctggattg tccttcaaat ctcctgtcaa ctcttgataa tgctcataag
     3301 cagtatccaa atcgtccatt tcttgataag aacgagcaat catccacttg gtcaaaagat
     3361 tttctggctc ctcactctgc aagtctagaa tatcctcata acgctcctgc tccagataaa
     3421 tagtggctaa acgaagcaag atttcttctg tatcctcagc gtcttctttt gcagtaagga
     3481 gataattttc tgcaccacta gcatcatgca attcataaga aaattgtgaa gcagctagca
     3541 agaggcgagt ttcaaaggga tttttctcta atccttgctt agcgatacgc agggcttctt
     3601 gaacttgatg ttccttatgt aaagcctgac tgtacccata ctcatagcct tcaaagtcag
     3661 gagaaatggt atcaagctgc ttaaagtaga gggtggcttt ttgatattct tcttgatcaa
     3721 aataaagact ggccaactca aaagctgtta agtcatcgta ttctaactcc agggcttttt
     3781 ctaaaaactc agtagccgtt tcaaatttcc ctaactgagc ataggcaaag ccaattcgtt
     3841 gataggtgga aatgcccgtt tgctcataaa tcgagcgatt atctaactgg gcataggctt
     3901 gaatagccgc ttggtaattt tccaactcac tatccaactc tgccaaaccc aatatcaaga
     3961 gagaatcctc tgagtaggtc aaggcctcca ataatttctc acgtgccaca tctgtcaaac
     4021 cttccagctg gtaaaggtct gccttcaaaa ccaaagacga gacataccag tcactgtcag
     4081 cttggatttc ctcaagatag gtaaaggctt cttctatttg accatcctcg ctagcaattg
     4141 cagctagatt aagatgaacc tctggaaaat cctctacaat tttcaggtaa atttccttgg
     4201 cctgaggata gaaaccaatc ccttcaagat aagttgccaa ctcatacaga agattacttg
     4261 aatcattttc taaagctttg gcgaaataat gctcagcctt agttaaatct tgctcctcca
     4321 aagcctgtaa catctgttga ctattgttca ctcttgactt cctcaccctc taattcatat
     4381 agaccactga ctaccttata ccattcgaaa atggctgaaa tgacaacctt agcagaggca
     4441 taaaccggaa taccaagtaa aactccccag ataccaaaca tagatcctga agttaacaaa
     4501 acaaagagaa cattaatagg atggatgttt aattgacttc ccaaaatcaa tggagagaca
     4561 aaacggcctt caatagtttg ttctacgata aagacaatca ctactttcaa aagcatgact
     4621 ggaccagcaa tcaaacccaa tactagagca ggaagcatgg ctagaaagct accaagataa
     4681 gggaccagat ttaaaatacc agcagtaacc cccagcgtaa ccgcatagcg tagaccaata
     4741 atcttgaaga agatgataaa cattactgct acaataatag ccactgtcac ttgccctcga
     4801 acatagttgg acaactgttg attcacatct gataaaactt gtccaacagg ttccttcaat
     4861 tttcttggaa tgaattgggt caaatagtta cgcaagcctt tcccatcacg caagagataa
     4921 aagagcatga aaggaacgat aatcaaggca acaatcactt gagaagcccc gctaataaag
     4981 gcactcaccc agttgactgc ctgagatgaa accttacttg ccaaaactgt agcctggcta
     5041 gaaaaattgg tcaaaacttg ctctaattga ggtctgaaat catctggcag gtgctgggct
     5101 accaatccat taacaatcct atctatatct tctaagtaaa caggaacgtt tcttgcaaag
     5161 gtcaaaacct gacgttgcag atttggaatg gcgactgcca agccccaaat gataaagaga
     5221 gcgatgataa caaagacaat agtgatagct ataacacgat taaccttatg cttctccatc
     5281 caatcaacaa taggattcaa caaataatat aacaaaccag acaaaatgac tggcaacatc
     5341 acaactgcta aaaagtctaa aacaggtgaa aatagaaaac taatcttact taaaataaaa
     5401 agattcagtc ccaataataa ggttactaaa aataccgtaa ttgccttgtt atctaaaaac
     5461 cacttgaaaa accaagatag gctaaaatgt ttctcttttt gctccataaa tacttccttt
     5521 ctattgttct ctcattatac catttttgaa acaaaataac tcttttttaa agtgcttaca
     5581 tctaattgga tgtctttaat ttgcttattt ttgtgatata atagtcttat ctttacacag
     5641 aggtatagta atgaaagaaa ctgtttattt tggaacttat acacgtcgta cttctcaagg
     5701 gatttacaag gcagactttg atacagaaac tggtcagctt tcaaatctag aactttttgc
     5761 agctgagcca agtccaacct accttgcctt tgaccagcac caacatttat acactgttgg
     5821 tagccaagac gataaggggg gaattgcagc ctatcaaact gacgggactg tgttaaatca
     5881 tgttgttgaa gaaggagctc cccactgtta tgttgctgtc gatgaaaagc gtgatttggt
     5941 ttacgcagcc aactatcaca agggacaagt ccttgtttat aaacgccagg aagatggtag
     6001 tcttctactt agtgatatgg atcaacacag tggccaaggt ccacatgaaa atcaagcttc
     6061 cccccatgtt cactatacag atttaacacc tgaccactat ctagtgacct gcgacttggg
     6121 aactgaccaa gtcatcacct atgacctcga tcaagaagga aaattatcta agctctatac
     6181 ctatcacagc aagccaggag caggctcacg ccatatcatt ttccataacc actataaaat
     6241 cgcttatctc atttgtgaac tcaatagtac tatcgaagtt ttaatctacg atggcgttgg
     6301 cgaatttgta cgtatgcagc ttatttcaac tttaccagaa gcttacgaag gctttaatgg
     6361 aaccgctgct attcatctct ctaaagacgg taaatacctc tacgcttcta accgtggcca
     6421 tgattctatc gcagtatata ccatccttgc ggacggtagc ttagagttat tagaaatcgt
     6481 tccaacgcat ggtcagactc cacgtgattt tgatttgacc cccgaccaaa aatttctcat
     6541 tgttgtccat caagactctg acaatgcaac tgtctttaaa cgtaattgtg acaatggtcg
     6601 tctagcagaa ctctccaacg acttccatgt tcccgaagca gtctgcatcc gttttgctcc
     6661 ttaaaacacc ataaaaaatg aacttggtat tttcaagttc attttttctt atagtctatt
     6721 tccgacatta atacggttaa tagcacgttg caaagcaatc ttagcacgac gttcttggtc
     6781 aatcaaatgt ttgtcttgtg cttcttcaat tgcacgttct gcacgaagtt tggcacgttc
     6841 tgcacgactg atatcgatat cacgagcacg ttctgcagag tcagcgacga ttgtgatcat
     6901 atcattggca atttcaataa cgccaccgtt tactgcaatc cagttcacgt gatctttatc
     6961 atcgatacgt tttaccttta cttcatcaac tgctaaaacc gcaatcatat tttcatgtcg
     7021 tggcaagatc cccatctcac catccagagt tcgaaccgat acatagctgg catggtgatc
     7081 atagacgaga ccatctggtg tcacgatctg gacagttaac tgagccatag atcacctctt
     7141 aaaatcccat tttttcagct tttgcaatca catcttcgat agaacctaca ccacggaagg
     7201 catcttctgg caagtggtcg tatttaccat caaggatttc cttaaagcca cgtacagttt
     7261 cagcaactgg aacataagaa cctggctgac cagtaaattg ttccgcaacg ttgaagtttt
     7321 gtgacaagaa gaactggata cgacgggcgc gagcaaccaa ggtcttttct tcatcagaaa
     7381 gctcatccat accaaggata gcaatgatat cttgcaattc atggtaacgt tgaaggacac
     7441 gttttacttc agcagcaact gcatagtgct cttctccaac gatttcaggt gccaaggcac
     7501 gtgagcttga agcaagtggg tcaacggctg ggtagatacc caattgtacc aacttacgtt
     7561 ccaagtttgt tgttgaatcc aagtgagcga aggctgttgc tggcgctggg tcagtatagt
     7621 catccgctgg cacatagata gcctggatag aggttacaga acccttcttg gttgatgtga
     7681 tacgttcttg caattgaccc atttccgtag caagtgttgg ttggtaacca acggctgatg
     7741 gcatacgacc caaaagggca gatacttctg aaccagcctg agtgaaacgg aagatattat
     7801 cgataaagag aagcacgtct tggccttcca catcacggaa gtattcagcg attgtcaaac
     7861 cagtaagggc aacacgcata cgtgctcctg gtggctcatt catctgacca aagaccatgg
     7921 ctgttttctc gataacgcct gattctttca tttcccagta aaggtcattc ccctcacgag
     7981 tacgttcccc aacaccagta aatactgaaa taccaccgtg ctcttgggca atgttgtgaa
     8041 tcaattcttg gattaagacg gttttaccaa ctccggcacc accgaaaagt ccaactttac
     8101 cacctttaag gtaaggggca agaaggtcaa taaccttgat ccctgtttca aggatttcag
     8161 aagaggtaga caactcatca aaagttggag cttttttatg aattggctga cgctctgcgt
     8221 cttctgtaaa aggagcttcc aaatcaatgg tatctcccaa aacgttgaag acacgtccca
     8281 aagtttcttt acctactggt acagagattg gacgacctgt gtccaatact tccattccac
     8341 gagtcaaccc atctgttgat tccatggcga tagtacgaac cataccatct cctaactcca
     8401 aggctacttc aaggacgatt tttgtttttc tttcgtcatt tttgtagacg acaagtgcat
     8461 tgttaatctc aggaagtttt tcccctgctg caaacaaaac gtctacaacg ggaccgataa
     8521 cctgagcaat tttacctgaa ctcatctcct tctcctattc tatataagat actgtcggtt
     8581 cctagctcaa ctaggtccta agttcatttt catacgagct ggactagagc ctattctaag
     8641 gcactagcac ctgctacgat ttctgtaatt tcttgtgtaa tcgccgcctg tctggcacgg
     8701 ttatactgaa ttgtcaaatc attgatgact ttcttagcat tatctgtcgc tgtttgcatg
     8761 gctgtcatac ccgcagcatt ctcagctgtc ttggcatcga taatggcacc gtaaatcata
     8821 ctttctgcaa actgaggcaa caactgctcc agaatttctt ctcggctggt ttccaattca
     8881 aaagtcaagc tgtactcttc atccgcttca tttggatcca agtcaacaat cggaagcatt
     8941 tgttccacac gcatttgact ggttagcgta ttgacatggt ggttgtagca aacataaagc
     9001 tcatcaaaga gttcattttg gtacatttca acagtttttg aaataatctt acgaacttga
     9061 tcaaagctag gttggtctgc caagccacgt aattcataaa gtggttgaat accgcgagcc
     9121 ttaaagaaat cagctcccat cccaccgata cagatcattt caaaaccttt accgtctggg
     9181 tggtattctt ctttcaactc cataacagct ttcaaaatag aggaattata acctccaacc
     9241 aaaccgcggt ctgaagtgat aacgatatag cctgtcttct tcacagaacg gctaatcaac
     9301 atcggattag ttgaagcacc agctccatta ccatgaagga tatctgtcaa aagtttacgc
     9361 actttctgag cgtaaacttg gaagttgcga gcagcttctt cagagcgacc taacttagca
     9421 gccgatacca tttgcatagc attagtgatt tgactcgtat tttttgttga ggcgattttt
     9481 gttttaatat catttagaga cactgccatc tgacacctct attcttattg gaagctagat
     9541 tgattgagaa actctgtaat cgcagcatcc aagactgctt cttctggcaa gtcttttgta
     9601 tcacgaatgg tttccaaaat ctctggatgt tgagcatcaa agaaggcatg gaactcttcc
     9661 tcgaaacgaa caatatcatc tactggaaca gtatccaaga aaccatgtgt caaagcataa
     9721 agaatggtta cttgtttctc aacaggtaat ggtttgtgaa caggttgttt caagacctca
     9781 acggtacgac gtccacggtt caacttagcc tgtgttgctg cgtccaagtc agaaccaaac
     9841 ttagtaaagg cttccaactc acggtatgaa gcaaggtcga tacgaagtgt accagcaacc
     9901 ttcttcatgg ctttgatttg tgcagaacca cctacacgag atacagatga acccgcatcg
     9961 atggctggac gaatacctgc attgaagagg ccatcgccaa ggaagatttg tccatcagtg
    10021 atagaaatca cgttggttgc gatataggct gagatatctc ctgcttgtgt ctcgataaat
    10081 ggtagggctg taattgatcc accaccaagt tcatcagaaa ctttagctga gcgctcaagc
    10141 aaacggctgt ggagatagaa aacatcccct gggaaggctt cacgacctgg aggacgacga
    10201 agcaagagcg atagttcacg ataagctacc gcttgttttg atagatcatc gtatacaatc
    10261 aaaacatgct taccttgata cataaattct tccgccatag caaccccagt ataaggagct
    10321 aggaagagca atggagatgg ttgtgaagca gaggctgtca caacgattgt gtagtccaag
    10381 gcaccgtact gacgaagtgt ttctacttgc gtacgaactg ttgattcttt ttgtccaatc
    10441 gcgacgtaga tacagatcat atcttgatct ttttggttca agattgtatc aatcgcaatg
    10501 gttgttttcc ctgtctgacg gtcaccgata atcaactcac gttgaccacg accaatcggt
    10561 acaagggcgt caatagcttt caaaccagtt tgcaatggtt ctgaaacaga cttacgttgc
    10621 ataacaccag gagctggtgc ttctactgga cgagttttat cagtgtggat ttctccaaga
    10681 ccgtcaactg gacgaccaag cggatccaca acacgaccaa tcagactttc acctacaggg
    10741 acttccatga ttttccctgt acggcggatt gtatcgcctt cacggatatc tgtaaagtca
    10801 cctaggatga taataccaac gtctgttgac tccaagtttt gagccatacc ataagagccg
    10861 ttttcaaaat tcaacaactc tccactcatg acattttcaa ggccatgagc acgcgcgata
    10921 ccgtccccga tataggttac aacacctgtt tcagtcacat caaaattggg tttgaaattt
    10981 tcaatttgtt gcttaattaa agcgctgatt tcttgtgcgt taattgccaa aagaacacca
    11041 ctttctattt caaattttct ttaacaactt taagttgttg tttaatactc acatcaattg
    11101 tcttgtgatt ggcaaaaatg acaaaaccac caatgagact ttcatcgatt tgttctttta
    11161 cactccttac tttcagagac atttttttct caatcaaagg gagcaaacga gtcttctgtt
    11221 catcagttag aggatgagca gacgtaatcg tcacttcaaa tcgatttgtt tctttttcaa
    11281 gtcggttcaa gcaatctaca agcacatcat aaaaaagatt tgctctgtga ttgtaggcca
    11341 gaacctggat aaagttttgt aataaaggcg acacagaatc ttggaaaaaa gcaattgttt
    11401 tttccttatc cgactcgtct actgccactt gttttaaaaa agaaggcaga cctgtttttt
    11461 caacaacttg cttgatttga gtcaagtctg aaaagatacg gtcttcttct cctttttcaa
    11521 gtaccaattg gacaaaaggc atgctgtatt tttcaattac ctttactgtt ttcttgtcca
    11581 ttaagcttct cctagctgat cgatatactg atcaatgagt gctttatggg catgactgtc
    11641 aaggttttgt gagatgattt taccagctaa gctgatggtc aaatctgcga cctcaccctt
    11701 aacactctgt aaagcttcta ctttattttg agcaatttct tgattggctt tttcttttaa
    11761 gtgtcctgct tctagtttag catctgctaa gatattagcc ttactttgct cagctgtttc
    11821 ctttgcattt tcaatgattg tcttagcttc tttacggcta ccagccaatt catcttcgcg
    11881 tttttgagcc aatacttctg ctttttgacg ggcttcttca gctctgtcaa tatctgaagc
    11941 aattttttca gctctttctt cgaaaatgcc tgtaatatta gaccatgcaa attttttaat
    12001 caagactagc aaaagaataa aagagccagt gattaaaaca aaattaccaa ttaattcacc
    12061 tactgttacg tgcatcagtt actcctttct attcctcttc aatattaatc ttattcccta
    12121 aatacacaga tgtcaaaaga gtaaaaacat aagcttggat gcaggaaata aagacagaaa
    12181 atgcagtcca agccaaatta gctccaaagg ctactggata ccaataaata gcttggtggg
    12241 aaagaagaag taacaaactc gtcatgacct ctcctgcaaa gatattccca aaaatccgca
    12301 aagccaaaga taagaagttt gtaaattctt ccaagatatt catcggtatg acaaaaacag
    12361 gactcataaa agattttata ctttttttaa atccacgacg acgaacgctt tctatatgtg
    12421 tcaacaaaat gacaagaaaa gataaggtta agtcatactg taaattagcg gttggcgaac
    12481 tccaccagtt agtcccatcg atcgtttgaa tctttgtcat taagccaagg ttattggcaa
    12541 tcaccatgaa aaggaataaa caaaggaaaa agagtgagta atctttcatg tagcgcgaac
    12601 caatgttagg ttctgtaaat ccaataacaa agtcatagac atactcaagt acattttgct
    12661 ttcctttggg tttcaaggtc atattgcggc ttgcccaata aataaagaca aaaataactc
    12721 ccacaatcaa caaagtcatg gctaacatag tcagattgaa gataacagga ccaatagaga
    12781 tgattggatt aatactttct tccatctaaa atcctccctt ttcttctcgt tccatgtatt
    12841 tatttgataa taaatgagaa gacaagagtt acaaagaaag ttccttcaat aaaggcaaca
    12901 cctaaaaaca tcaaactacg aaactcagaa agcatatctg gttggcgtgc tactgattta
    12961 aacagtccat tcatcaataa accttcaccg acagatacgc ccatacaggc aatacataag
    13021 cctaaaaatg ttaaattcat aacaaattct cctttaaaat aaaatttact tacttagtgt
    13081 agtcctaaaa tttaaatttg tcaactttta accgctattg gaagcgttta ataaaaatta
    13141 tttccatttt gctaaatttc aagttcaagt tagccatcca gaagtcttct ctgggtgact
    13201 tgtagtccaa gcatttttta ggatagttgt taatccactt ttcgatgaat gcgacttctt
    13261 tgggagtcat tttcttggtt cccttaggta accatctacg aatgagcctg ttgtgattct
    13321 cattagttcc cctttcccaa gaggcatagg gatgtgcata ataaatgtgc tcctcagaaa
    13381 atacattaga caagcgattg aattccgttc cattatctgc cgtgatggaa agaatcttgt
    13441 gttgttttaa gatgagtttt agagcctgat tgaccacctc agcactttta tttggaatca
    13501 atcggatgat ctgatgtcta ctttttcgat ccgtcaagac aagcaagcag tagtttttcg
    13561 ctctcgtaag tagaaccgta tcaatctcat aatgcccatt ctccaagcga aaattgatag
    13621 cttcaggccg ctgttcgatg gattgaccag caggtttaaa gttggtgctg gcctgtttct
    13681 taagcgcttt tccttttcta gggtaaagca gatcctgctt gctttacccc aattttccat
    13741 gatgaatcca atagtaaatg gttgaaattc ccacgttaac ccctttagcc ataaccatca
    13801 tttcaggcaa aaatttttgg ttatggtagt ggagaatctt ttcctttagt tccttggtca
    13861 cgcttgatct cttgaccgag tgcttgcgat tattttcata agactgttga gcatagtcgg
    13921 cagaataaac ctctttgaag cgcccttttc caagacattt tcggactgtc ctacgcttga
    13981 ttttagtgtg gatagtttga ggagcttttc caagtagaga ggcaatttct ctatttgatt
    14041 ttccttcttt tttccatctt tcgattaagc gacggctatc gattgtcaaa tgtttacctt
    14101 ttgtagtata attgtcttgc atttctgtgc ctttcttgtg tttgtggttg aacaacaagt
    14161 ataacacaaa ggtgttttct tatgcctaca agagctttca ttatttccat tttcttttgg
    14221 atttcactct attctgaaaa acttgtgtat atttactgaa gctagcaagt cttacctgta
    14281 aatttaatga aagcaacaca aaatccgaga ggggaatctc ggattaatgt caatttaaaa
    14341 agatagagag tttttagttt aaataaattg ttttaaaata tcaacaacat cacttctttt
    14401 cttaacctga taagccttga ttcctaattt tggggctacg attatattgt cctcaatatc
    14461 gtctagaaag acacaatttc taggttataa ctggtattta tcgatagtta ctcatatata
    14521 tcagtccacc tccatactca ccttacagat tcttttgata ataatatctt tgcctaatgt
    14581 agagatagtc ttgcaaagaa aaaacttcct tgtagccatg tttctgataa aagtccggtg
    14641 cctggaactg gtaagtattg acaaaggcaa aacaacaatt tcgattctta gcttcacttt
    14701 ctgcctgttg caatagtttt gaaccgattc cttgccctcg cagttcctct tttacaaaca
    14761 aatactcgat ttctagccaa tttccaaaag tctctgctat caaacccgca aggagattgc
    14821 ccttttcatc ttcgacataa agattaagtg gctcactttc agcctcttct ctttttgaac
    14881 ggttataaac acgaatcaga ttccctattt cttgcgattt atgtgattcc ttattttcca
    14941 atctaaagta taatgaaatg aaataaaaca tgcgcaaatc gattaaggaa tttaatctaa
    15001 tttctaacaa tgtcttagaa atcaaagtgt actattttaa cttcaatgca ctatacatct
    15061 aatactcaat aaaaatcaaa gagcaaacta ggaaactagg cgcaggctgc tcaaaacacc
    15121 gttttgaggt tgtagatgaa actgacgaag tcagctcaaa acatggtttt gaggttgtag
    15181 atgaaactga caaagtcagt aaccatatat acggcaaggc gacgctgacg tggtttgaag
    15241 agattttcga agaatagcaa aatggaaaaa ggagtgagtg aagcacatcg cctccccact
    15301 cctttttctg tttttaggct gttttttcaa ccttcaagat ttttacatca tagctaccaa
    15361 caggcgtttc aatggttgct gtgtcacctg ttttcttgcc aatcaaggcc tgcccaattg
    15421 ggctttcatt tgaaacctta cctgcaaagg catccgcacc agctgaacct acgataatat
    15481 aaacttcttc ttcgtcctca ccaatttctt ggatggtgac tgttttacca atcgctactt
    15541 cgtcctgggc aactgcgtcg ctattgacga tttcagcata gcggattttt gtttctaagc
    15601 tagagatttg tccttcgaca aaggcttgtt catccttagc tgcttcgtac tcactgtttt
    15661 ctgaaagatc accgtatgaa cgggcaatct taatgcgttc taccacttct ggtcgacgaa
    15721 ccaatttcaa ttcttctaat tctttttcaa gtttctcctt ttcctcaagg gtcataggat
    15781 atgttttttc tgccattttt ctcaactttc ttctgataat attttctaaa gaaaattatg
    15841 tgaagtatca cataatttta gtttgtttag tttaatttgc tgttgacatg ttcagcgaca
    15901 ttgcggtcgt ggtcttcttg attgttagca tagtagacct tgccttctgt gacatctgct
    15961 acaaagtaga ggttatcgct cttagtttga ttgatgcttg actcaatcgc atccagactt
    16021 ggactatcga ctggaccagg catgagacct acatttttat aaacattata aggtgaatca
    16081 atgtcggtat caatcgcaac atcctcagct agactgatat tttgccccag ttttccttgg
    16141 gcatacaaga ttgcaatatt actttgaagt ggcatatcac gatttaaacg attgtagaat
    16201 acacctgcaa tgagcttacg atcttctgtc ttggcacctt ctttttcgac caaggaagca
    16261 atggtcaaca actcattgat agtcaagttt ttagatttga tagtactata gtaaggagat
    16321 aggttcttat ccatagcagc taacatctca tcaatcaagc tctcaatagt tgtgctttcc
    16381 ttgatagagt atgtagctgg gaaaaggtat ccttccaaac gataacgcgc accgctgtct
    16441 tttacaggca aactttccag taaagtagga tatttcgcta ctgcttgact gataaacgtc
    16501 tcatcttgaa ctttagccaa gaaagcctcc gctgtcaaag actctttgaa gtcaccttgc
    16561 aattgaccca cagtttgagc aatctgatcc aaggtataac cttctggaat tgtcaaagtc
    16621 gcaagtacag gttcttgcgg ttcatctgtt ccaccttttt gcaactcttt gagtaagtct
    16681 tctgtactca tactcttttg caaattgtag taacctgctt tcaagtcggt ataattttta
    16741 tacttggcat aaaaactaaa aatcagacca tgctttacca aaccagcttt ttcaagcgtc
    16801 gtaccgattt cttgaacgtt tgaaccttct ggaattccaa ccgtcacata tttcttagaa
    16861 ttagcatcga taggtaacaa agaatctagc acgtactggt aaccaaagta accacctgct
    16921 gagagcaagg caaggaatac aaggaatgaa atcacaaaag ctttcacatg tgacttcttc
    16981 tctttcttag gtttaacggg ttttgctcct tctctacggc tacgacgtga tgtatcgctg
    17041 atgatatcca ctgtttctgt agcaggcgta ggtgtttctg gacctgcttg ttctgctttt
    17101 ttctctgccg tcgtatagga aacagctacc cttgttgggg tttcattgta ttctctttca
    17161 agtttcttag gtctaacagg acctggacct ggtcttgatc cactttcttc cgctggagaa
    17221 gaaggtacat cttgacttgg atgacttgga acaccaggag tttctctttg aatctcatct
    17281 gctggagaag ctggtacacc ttgacttggg tgagtaggca cggtaggagc ttttctcata
    17341 atctcctcta ccgttgacaa ggaatcagcc atgagttctt cagctgaagg ttcatttgca
    17401 ggagtgcgaa ctactgcctc atcttctttc agaacttcat catagccttt tactttttct
    17461 aaatctctca gaatctgctc tttaaagctt aatttctctt cttctcttga cttttcactc
    17521 aaaagttttt cctccttgtt gataatccat aatattatat cttaaaagtc caaaaaaagc
    17581 aatctatgat acttttccta acttattttt tcatttccca gaccatatca taccatgttt
    17641 cccctgcaaa ggttgactgg gactggcctt cgttgacaaa tccatgtttt tcatagtagg
    17701 cgatgagata gtcatgacag gttagattaa tgccatctct ctcatcttca agagcaactt
    17761 ctttcaaggc tgtcagcaat ttctgaccca gtccgagtcc ctgtgcctcc ttggcaatag
    17821 acagacaggt cacagagata taaccaccag gctcatgact atagtctttt atttcttctg
    17881 taaaagactg gtcttgcaga tggcggtgca ggccaactgg tccttcgata taacccatga
    17941 ttcttccttc tttttcagca accagaaaag aggtctgaat ttctctcaaa tgtgcttcaa
    18001 agacagaagg aggaatggct tcttcgaccg aaaaattttc aaattcaagt tcaacaatcc
    18061 gatccaaatc ttctaatctt gcttgtctga ttttcattgt tcctccagat aaaagggatt
    18121 aaaccaaatc atactatagc cctggctagt tgcatagagc aaagtttctt cttcatcaac
    18181 aaaaccgttc atttcaaaat aggaaagcag ctcatcagga ctctccaaac gaatcccttt
    18241 gcaatccagc tcaactgcca cctctttcaa ggctgcaaga agaagtgttc ccaggccctg
    18301 tctctgatgg tcagactcga tgactaaaga atgtactttt agacattgcg gattgtctga
    18361 ctggggactt gataaaatat agcctaaaag ttgattttca tccctagcta gaagaaaggt
    18421 atccgcacac ttacggatac tttcttctaa aatatgggaa agttgctgct tttcagctgg
    18481 aaaagacgag gtctgaagtg cccctatctc aggcaaatca gacttgcttg cctgaatgat
    18541 cttaattgga atttccatgg gaacatccta ttgaacattg cttgtcaagt tagataagag
    18601 acgctcaaat gagtattcat aggtttggat gtctcctgct cccataaaga cgtaaacagc
    18661 attgtcatgg tctaggagtg gagaaacatt ttcaacagta atcacttggt gttttttgtt
    18721 gattttgttg gctaggtctt ctaccttaac gtcaccatga tctacttcac gagccgagcc
    18781 ataaatttgc gctagataaa cagcatctgc ttggtttaaa gcatgggcaa agtcgtccaa
    18841 caaggcaatg gttcttgtaa aggtatgcgg ttgaaagact gctacaattt ccttgcttgg
    18901 gtatttctga cgagccgcat ccaaggtcgc aataatttct gttggatgat gggcaaagtc
    18961 atcgataatc actgtatcat tgacaatttt ctcagtgaaa cgacgtttaa caccggaaaa
    19021 tgttttcaag tgctcacgca ccaagttcaa atcaaatcct gctgtgtaaa gaagaccaat
    19081 aacggctgtc gcattcatga tattgtgacg accaaaggtt ggaatgtgga attgccccaa
    19141 gttttgtcca cggaaatgaa cggtgaaggt tgaaccagtt gttgaacgaa gaagatcact
    19201 agctacaaag tcattgcctt cagcttcaaa accataataa taaattggtg catcagacgt
    19261 aatcttacgc aattcagcat cttcaccata gacaaaaaga cccttggtaa tttgtttggc
    19321 atagtcgtta aaggcattga aaacatcctc gagacttgtg aaataatctg gatggtcaaa
    19381 gtcaatgttg gtgataatag agtattctgg gtggtaaggc atgaagtgac gctcatattc
    19441 gtcagattca aagacaaaat atttggcatt agccgaacca cgacctgtcc catctccaat
    19501 caagaagctg gtatctgtaa tgtgagacaa gacatgagac aacatacctg tcgttgaagt
    19561 ttttccatgt gctcctgcta ctcccatgct aacaaagtca cgcataaagc tacctagaaa
    19621 ctcatggtaa cgtttgtagc tgataccatt ttggtccgca taggcaattt cgacgttgtt
    19681 atctggacga aaggcatttc cagcgataat ttccatatca ccgtctagat tcttttcatc
    19741 aaaaggaaga atggtaattc ctgcctgctc aagaccgcgt tgggtaaagt agtacttttc
    19801 aacatctgat ccctgaacct tgtgccccat ctggtgcaac atcaaggcca aggcactcat
    19861 ccctgatccc ttaattccga taaaatgata tgtctttgac atgttttctc ccctattctg
    19921 tcattctggt cagattcaac tcttgggcaa cccgacgttc ttgttctgtt tgtttacttt
    19981 ttttattgta gatttggctc ttctttagaa aatcataatt gtttttcttt ggagcaggtg
    20041 ctgacacttc ttcattcttg gtagggatag aatgaacttc ttccgccaag atataatgag
    20101 actgggtcaa tttttggcta tatttgacaa attcaccagg attttccttt tggaaaggag
    20161 ttgtcggttg attgccctgt ctaactagac tgggctgaga atgacgtctc gcaaggctga
    20221 aatcctgagt taggtagtta gcagagcgtt tctttttcaa gtccgcacgc gcttcttcac
    20281 gcgccacctc cgcatagctc tttccttctt ttttaacccc taaaggagcc tttttaggtt
    20341 tttcgacttg cttttcaatc ggttttactg gtttttcttc agtaatagga gcccattcta
    20401 aataattttt atctcgatac tcacccttga tattactgat cagatcagac tcatcataga
    20461 gattcatgac tggcatttca gtcaacatga cctcgtcatc tgacaccaat ggaaatcgtt
    20521 cttgtttcat tttctatttc ctttcaacac ttcattatag cgtattgtct tgatttttca
    20581 agtgctggct tcagaaattc ccaaaatttc tctaatttct gctagggtca gactaccacg
    20641 tgactctgtg ccatccaata cttgtgacac cagatgtttc ttttgttctt ggagttcctg
    20701 aattttttct tcaatggttc ccttggtcac caagcgatag acctcaaccg tttcttcctg
    20761 acccatccga tgggcacggc caatggcttg cgcttccacc gcaggattcc accaaaggtc
    20821 aaccaagatc actgtatctg cacctgtcag gttcagaccg accccaccag ccttgaggga
    20881 aatcagaaag gcatctcttt ctccttggtt aaaggccttg gtcatgtctt gtctttcctt
    20941 ggctggggtt gaacccgtaa ttttaaagga tgtcaggccc aagtctggca gttcttgttc
    21001 aattttttcc aacattccct tgaactgaga gaaaatcaag acacggtgtc cgccgtctgc
    21061 cacctgtacc agtaggtctc ggagactatc tagtttgccg ctggctccct gataatcttc
    21121 cataaacagg gcaggagtgt cacatatttg acgcaagcgc atcaaaccag ataaaatttc
    21181 cacacgactt cgctgaaatt cctgttctga cacttgagcc agatggtctc gcatctgttg
    21241 taactgggca aggtaaatag ccttttgctg gtcttccagt tcatttttat aaaccacctc
    21301 aatcaagtct ggcaattcag tcagaacttc ttctttcttg cgtcgcatca cgaaaggctt
    21361 gataaactga gccactcgct ctgctggcaa tttcataaat tctttcttgc ttggcaaaag
    21421 tccgggcatg acgatttgga aaatagacca caactcaccc agatggtttt caatcggagt
    21481 tcctgacaag gcaaagaccg acggcaccac aaattgtctc aaggtctggg caatcttggt
    21541 ctgggcattt ttcatgacct gagcttcatc taagaaaagg aagtcaaagg ccatcccctg
    21601 ataaagctca ctgtcctgac ggaaggtggc atagctagtc acatagattt gatggttatc
    21661 ggcaagaatc tcctcacgac ttgctttcaa accatgaaca acagccacat ccaactgtgg
    21721 agcaaatttc tgaaactcat ccgcccagtt gtaaatcaaa cccgacggag cgagaatcaa
    21781 gactcgactt tcttttgtca cttgactagt caaaaaagca atggtctgaa gggttttccc
    21841 aagtcccata tcatcagcca aaatcccacc aaaaccataa tgatggagca tctgcaacca
    21901 gccaattccc ttttcctgat aatctcgcaa gtcagccttg acctgagttg cttgcaaagg
    21961 aaagtcctct ggatgtgtca aatcctgggc cagattctgg aattcttgtg aaaaagaaac
    22021 acggtctcgc ccttcaaaga gatgagctaa actgtaggct aaggatttcc gagcctgcaa
    22081 ggtcccatct tttaattcaa attgccccag ttcctgtaga ttttggcgaa ttttcttggt
    22141 ttcttcatcg aaaaagtaaa cttgattaga cgaatcaata taaaaatcct gattggcaac
    22201 caaggcctgt atggcttggt cgatttcctc ctgggcaata tcttgaaaat caaactggat
    22261 ttccaagaga cctcccttgg aggcaatctg cacctgagga ctcgctaggc tataaagctc
    22321 ttctagttta tctgataggt caacatgccc gagtttttca aagactggaa tgatatcatg
    22381 aaaaaaatga tagacagact ccgcttttaa ggcctgacgc caagattgaa aatcggcttc
    22441 aaagcccgca gccaaacaga cttggaaaat tctttcttct aagtccgcgt cacttgaaaa
    22501 tggtaattct tctagctctt gtcggctaga tacctgtcta tttccataat caaactgaat
    22561 ttctaaacga atccgattat cttcttccct gtcaaagtaa aaagagggcg caaaagtttt
    22621 gatttgtaga cgttctggag ctgaaacggt gcccatctgg ataaaaagag tcagacagga
    22681 ggccaatttg tctcgatcac tgctatcaaa ttgcaggtat ttctttcctt gtcgatccac
    22741 aggtaacgct ttaatttcct tgagaagacg catctgctgg tctgttaaaa aataaacctg
    22801 acctttatgg aaaagtactg ctccttgata aaagacattg accctaggac tctcactgat
    22861 ttccatttca aaatagtccg aatattctgt tactgtaaag gcaaatagat tggcatcagc
    22921 atgcatatcc tgaaaaagca gggtttggta gctatccact tgatggtcaa attgaaaatg
    22981 gggcaaggcc atcagtaaat tcacaccctg ctcaaaaaag gtcagaggga aaaagaggtg
    23041 ccgaccttgg ttttggaaaa agaggtctgg aaccagccct tcctccgtta gtccgtgcaa
    23101 gaaagtcaaa agttcttggc tggcatcatc aaaggcttcc caagaaagag actcctcata
    23161 aatcttgcca atcatatacg actttctctg ctcgacaatc cttaaaaaaa gtggaatatc
    23221 ccgaatgaca tagtattttt ggctattgat ttggccgatt ctcagagtcc acaagatatg
    23281 attggttcct gcttccacct gacccacagc tgataactca taggcgcatt ctgattttgg
    23341 agataaaatt cgatccaaaa acttgccacc caaggtcacc ttggtttcaa cggcctcttt
    23401 ttcttcatga ccttcttcca gactccacaa gatttcctga ccacgctcat catttttcag
    23461 aaaatgctct agcgctgcca aatgcacaca gtagcccctc ttttgaaaaa aatcacaggc
    23521 acaaaaaatc aaatcatcct ctaaactata gcgcagttct tcttctgcaa cgcgagcgta
    23581 gagccgattg ttcttttcct tgatgatatc aaccttacca gtttcataaa gggcaacacc
    23641 ttcgatacga attttccccg gaatcaattt agccatattt tcacctttac cttatctttt
    23701 tattatacca tattttcgcc tatgaaaata gccttctagg aagacttttc tcctagaagg
    23761 ctggattttt aacatttggc aaaagtagcc acaatccgct gacagacttc ttgcaacaga
    23821 gatttgggca tagctatatt gatgcgggca tggagacttc cttcctctcc aaaatccaaa
    23881 ccacggttga ggataacctt ggcttcattt ctcaacaact cttgcaatgt ttcatcagtc
    23941 aggtcataag ctgaaaagtc aagccaaatc aagtaggtac cttgcggttt catgaccttg
    24001 attttagtct cttttccaaa tagatccacc acataattga tgtggtcttc aaagacttgc
    24061 ttgagttcct ctagccaatc tttaccgtat cgataggcag cttctgtcgc caaataaccc
    24121 aagcctgaaa tttcatgctg attattggcc aacaggcgtt tctggaaagc cagtctcaac
    24181 ttaggatttt caatgactgc ataggaattt tttgttccag caatattaaa tgttttagtg
    24241 gcactgctca agacgatagc aaaatttttg aaggcaggat tgatggtatt gaaagactgg
    24301 tgtttgtgac caaagagggt caaatcttgg tgaatctcat ccgaaactaa caaaacaccg
    24361 tgtttttggc agagttggcc aatcttctcc aacacttctt tttcccaaac acgtccacca
    24421 ggattgtgag ggttgcaaag aacatagagt ttaacctcct cttccaccaa atccttttca
    24481 agttggtcaa agtcaatctc aaacagacta tccttttcca ctaaggaatt agtaatcaat
    24541 ctacgattat tcaacttgac actgcgagca aagggtgggt agacaggcgt gttaattaaa
    24601 accgcctcgc cttcttttgt aaaggtttga atagctgttg agatggctgg taccacaccc
    24661 tcgataaaga caagagcctc tttgtcaaag ttgtaaccgt attgtgtagc ttcccacttt
    24721 tgaacttcct taattaagtc ttcactggca taggtataac cataaaccag ttggtctgcg
    24781 taagtttgca cggcttggtg gatttcaggc aagactacaa agtccatatc cgctatccaa
    24841 gctggtagaa cttcactatc cgtttctgtt tctttccatt tataggtatg gtgccctaaa
    24901 cggttgggca ggcttgtaaa atcatatttt cccatctttg tcttatcctt ctaaggcttg
    24961 gcgcaaatct gcaatcaaat ctctagcatc ctcaatccca atagacaaac gcaagaggtc
    25021 atctgtcaaa ccataagaat ggcgtacttc tgctggaata tcagcatgag tttgagtcgt
    25081 tggataagta ataagacttt ccactccacc caaactttcc gcaaaagaga agaccttgag
    25141 actgttcaaa atatgaggaa tgcgtgtttc atcggctact ttaaaggaaa tcatgcctcc
    25201 acgaccagtg tagagaactt ccttaactgc tggagaatcc ttcaaaaagg caaccacttc
    25261 ttgggcgtta gctgttgagc gctccatacg aagagacaag gtcttgagac cacgaagcaa
    25321 ctggtagctg tcaaatggag acaagactgc ccctgttgta ttaagattgt aaaaaagctt
    25381 ctcgtatagt tctaaactat tggtcacaac cactccagcc aagacatcat tgtggcctgc
    25441 tagatacttg gttgctgaat ggagaacgat atctgctcca tcttcaatcg gacgttggta
    25501 gatagggcta tagaaggtat tgtccaccac cactttggca cccttagcat gagccaattt
    25561 tgctagtttt tcgatatcaa attccaacat caagggattg gttggggttt cgatatagag
    25621 aacatccaca tccttttcta actcggcaat caactcttct tctgtattgg cataggtaaa
    25681 atggaaatga ccttcctgct ccacttggtt aaaccagcga aaagaaccac cgtaaagatc
    25741 acgcactgcc aagaccttac ttcctactgg aaagacgcta aaggccagta caatagctga
    25801 catccctgag ctagtcgcta gggcatagtc tgctgactca atagccgcca agacttcctc
    25861 agccttacta cgagttggat ttttagtgcg cgtatagtca aacccagtag atcgaccaaa
    25921 ctctggatgc tgataggtcg ttgaaaaatg aagtggtgtc accaaagcac ctgttgcctc
    25981 atcagacttg atccctgctt gtgctaaaat tgtgttaatg tgtaattcct tgctcataca
    26041 attcctccaa atctatagta actattgtac cacttatttt catcaactca ttttcttctt
    26101 ttcaagagct agttatagtt tcaaactata taaaaaggga gtttttcctg ctccctttaa
    26161 tagactataa aatggtgaat ctcaaaagac accttcactc tatcatttgc tcctgcacaa
    26221 aacgagcata acgctcatga ttttccagta gttccttatg agttcctgag ccagtgattt
    26281 tcccctcctc taagaagaaa atacaatcca catcttttac cgttgacaaa cgatgcgcta
    26341 taatcacaac cgtcttctcc tttagtacag aatagaggct actgataatc gcatactcag
    26401 aatccgcatc aagattagca gtggcttcat caaatataag aatttcagca tcttttaagt
    26461 aggctctagc tatttgaagt ctttggcttc gcccccctga caagagtcgt ccgcgttcac
    26521 caacttcagt atctagtccc tctttcatgg agcgaatctc atcacctagt gatactaagt
    26581 ctagcacttt catcaattca tcatcagtta ctaagcgatt caaaccgaga caaagattgt
    26641 cacgaatact gccagataag actgcattat tttgtgaaac ccaagcgatt ttacttctcc
    26701 attcttttaa gttaaaatca tatatacttg attgctccat tagaatatct cctgaaagcg
    26761 gtttataaaa ccgctctaac aaacgcacaa tcgttgattt tcctgatcca gatggcccaa
    26821 caaaagcaat tttttgcccc ttgaaaattg aacaagtaat atcctttaag acaggtcgat
    26881 tttcatcata accaaaatag acatggttaa aattcaaccc ttgtcctgat accgattttc
    26941 ctccctcaaa tttttcttta ggaactgcaa gcaagttctc cagtgcaact gaagatccct
    27001 tgctactaga ataaatagtt acaaaattag ctatattact aataggatta agtaattgaa
    27061 agaggtaaat caaaaacgaa accaaggttc ccacagatat atatcctgcg ctgacccgat
    27121 aacccccata ggttagcatc acaactatag tcgcaaagat aaataagaga gcaaacgggg
    27181 tctcaaaaga agtaacccta tctgatttca gtgaattgtt ttgtaccctt tcaatacaat
    27241 tatccaaaac atcctgtaca cttttctctg cttggttagt cttaattaat tcatgttctt
    27301 gaatcttttc agtcaattgc cctgttaaaa atccgatttc ctcctgtaaa cgacgactat
    27361 acttttcact gatattggaa aggggcaaga taataaacat catacaagga agagtgatga
    27421 ataaaagtag agaaagattc caatcaagac taaataagac tacaatggaa ccaagtacca
    27481 taactaaact cagaataata tttgggaaag tcgtaattaa aaactcacga atgacactcg
    27541 tgtcattgac aatggcagaa gtcaactccc cactttggct cttatcaaag aaggatttct
    27601 ctgcataaat caacccctct atcacttttt tcctgatttt tgctatcttt ttttcacccg
    27661 attgactaaa cagatagtaa ccaatagaag aaaacaaggt ttgaccaata aaaatcaaaa
    27721 acgattgaaa tactttggaa cctatatttt caatagaact cccatctatt aaacctttta
    27781 agataagggg aggcaacaaa gcaagtagac tagacagaac aaggaagaaa ctccccataa
    27841 tcaccttagt atctactctt aataatttta atttcataaa tactccttat aatatttcaa
    27901 cggataaagt cgggaataac tcaatttgag gataaaatct aataaatctt cctataacaa
    27961 aacgcataac atctaggatt ttatatacct gatattatgc gtttttaagc acaaagactt
    28021 cttacacaaa cttatctaca attagatttt atttgacatg ttttgccaat tcttcttggg
    28081 cttttttatt ggattcttct ttttctttca accatttttc tctggctttt gcatattcgt
    28141 ctgttgtgac aatcttatct tgtactttga ggtatttata tgattcaacc ccttttgtac
    28201 cggttaaacc ataggcagca gcaaatggta cggttcttct caatgatggt gttcccccac
    28261 gcgaaacact tggaagaact aaagaactat caatcaacca agcttgaata tcagcatatt
    28321 tctcataacg tttggctgga tcttgctctt tattagcttc ttccaacatt tgagtataga
    28381 catccagtcc aacttcctta gccttgtcat tggcttctcc aggctctagt ccaagatttt
    28441 gtagaactcc tccactatta gtattaaaaa tatcgagata ggttgacggg tcttgataat
    28501 caggtcccca accgccatga tataaatcat agtctttctg agcagctgtt tgagcaaagt
    28561 agcctgaact gtcaaactca tctgatgtta attgctgaat gtcaatcact acattatcag
    28621 aacctaaaac agattcaatt gattgtttga tagaactaac tccttgtatg cctactttat
    28681 ctgttacttc cacagtctta tccaagtgga ttgggaattg aacacccttt gcttcgagtt
    28741 ctttcttagc ttccgcaaac ttagccttgg ctttctcagg attgtagtaa gggtcttgac
    28801 catccgcaaa gttgatacct tgccattcct taccatagtt gaccatctta gaggctacaa
    28861 cttcaccaaa gtcttttccc ttgatactga caaagtttgg aggaaccact aggttacgca
    28921 aaatctttgt tgcaccttct ttcccttcag actgagcccc ataagatgtt ctgtcaaaag
    28981 caaaattgat agcctgacgg aagtttttat tgagaactgc ttcctgagtc gatttctttt
    29041 caatgtcact tgttttagaa gtataattgt aagacttcct atctaggtta aaattaaaga
    29101 aatatgaagt tgaattttgc atactataga tgatattgtt tttgtatttt tctttaatcc
    29161 cttcatagct ggagctgtta ggaaaaagac gagccgtagt ataagcacca gctgtaaaat
    29221 tacgttccag tgattcttgg tcgctaccat catagtaggt caatttcaca tcgtctacaa
    29281 agacattctt agcatcccag taattagggt ttttcttata ttcaatagca gattttgaga
    29341 caagtgcttt catcaagaaa ggtccattgt acaaaatact agatggatcc gccttcccaa
    29401 aatcatcccc ttttgatttc aggaaatctg cattaacagg aaaaagtatc gttgcaagtg
    29461 tttttgaatt ccagtaaagt tctggtttaa ccaaagtata ttgaaccgtt tggtcatcaa
    29521 gtgccttgac accgacagtt gaaaagtcgc ttgttttacc agtgatatag tcatccaaac
    29581 cagcaacaga gtcctgcact agatacaagg cttctgattt tttatcagct gcatattgca
    29641 aacctgtcac aaaatcctgg gcagttacag gcgcatattc ttctccctca gaagtaaacc
    29701 acttggcatc cttacgaagt ttgtaggtat aggtcaaacc gtcctgagaa acagtccaat
    29761 cctctgctaa tgatggaata atattcccat attggtcatt ttctaataac ccgtctacca
    29821 aatttgcaac aatatcggat gttgctgcgc ggttttctgc tagatagttc aagctagatg
    29881 gatcacttga ataaacatag ttgtaggttt ttgacgccgt gctagaattt ccacacgcgc
    29941 tcaataaaac tcctgtaccc aggacaagac ctgccaaggt tagatatttg ctcttagact
    30001 ttttcatttc cggaacctcc tgctttaaat atttgtttta ttatacaact cttggtttgt
    30061 ttagtcaatt gttttttcca aaaaatcaaa aaaacctcat tttctatttt tgaaagataa
    30121 ttttagctat ttttacgcta aaaaaggaat aagtttcaag ttctcctaaa agattgttca
    30181 acttattcct tttatttata aatgctacct tacgaaagct taaattttgc tcgcaggcga
    30241 tctgcttggg cttttcctat taccttatct aacaaatagg tacgcagact cataaccata
    30301 taaagtccac cccccatggc accgacaaga gctacataaa ataagctcca caaacgtcca
    30361 cttggttgga agaaaaatcc taacagccac tggatggttc ctattaacag aaacatgact
    30421 agggtcagca aactgattaa aatggttcgc ttcaaaatca ccttgcgctt gacaccagtt
    30481 actttacaaa tatcccgata catcaagacg ttaggaatga tgagagcaat ggttgttgaa
    30541 atcaaaggac cataactgtg gaagagggcg atggtaggta gttgcaagac tagcttggca
    30601 atagaaccat agataaaata gagaacggcc tttcggttgc ggaacatggc ctgaagcatt
    30661 ggagacaaga ccatgtacaa gcctaaaata atagactgca aaactgcaaa gacaaataag
    30721 cccagagcca aactatctgg cttaccatag aagaccgtat aaagaggttc tcctaccata
    30781 accactccaa ccgttgctgg tagcaagaac ataaagagta gggtgagact gtcctgaacg
    30841 agacgagaag ctgctttcaa gtcccccttg acatagtttt ccgtcaaaag tggcaaacca
    30901 acactcccaa tcgaaacccc tacagaaatc aaaatcatcg tgattttatt aggattggct
    30961 gagaaataag aaaacatgac aaccaagtcc tcattgctgt agttggtaaa ccagctcata
    31021 ctattgataa aggtcagctg atccaaaatc tggaagagct ggatggcaga ccctgtcagg
    31081 ataaaaggaa tggcttcctt aatggtatca accaagagac gcttactgtt aatcttatct
    31141 cctgtttcaa agactctttt gagtgaacct tcttgggcaa ggaaataaat caagactgca
    31201 aaactggcta ccataccgac aaaggcagca aaggttgatt gggtaacggc tgctagataa
    31261 tctcctgaac cgagcttcat aatgataaag gttgctagga gcatccagat aacacgaatg
    31321 acctgctcag caatttggct catggcatag ggtttgaggt tattcatccc ttggaaaaat
    31381 cctcggataa cactcataga cgggaaaatc aagactcccc aagccaagct ttgcatgatt
    31441 gggatcaagt ctttgcccac gccagacaag tctgctagcc aaggagcaaa gacatacaag
    31501 actaaagcaa aaaccaggcc tagtcctgtc ataaagccta agaagctccg aatcagggca
    31561 aagctatgct cttcttctcg catggtatta tacttggcaa cttgcttggc caccgcaact
    31621 ggaatccccg ctgttgaaac caacaagaac caagcataga tattgtaacc catggtaaag
    31681 agaccatttg ccttagctgc ataagccccc atccagatgt accaagggat aatgtaaaca
    31741 gccccgagta ggcgactgat aaagttacta gccgttagcc aagcagtccc ccgtaacatc
    31801 tgggcctgct ggtgattgtt ttcgtgcgac atagattcct cattcaattt tgatagctag
    31861 gaaaaactcc ttatcttcca ttataaactt ttccttgtta cttgtaaatt tacgactttc
    31921 ggtttacaat agaaagtatg attaagattg aaaccgtatt agatatttta aagaaagatg
    31981 gcctttttcg cgaaattatt gaccaaggtc attaccacta caactacagc aaagttattt
    32041 ttgatagcat cagctacgac agccgaaaag taacagaaga cactcttttt tttgcaaaag
    32101 gcgctgcctt taaaaaagaa taccttcttt ctgctataac acaaggctta gcttggtata
    32161 tagctgaaaa ggactacgaa gtcggtatcc ctgtcatcat tgtgaacgat ataaagaaag
    32221 ccatgagttt gattgccatg gagttctatg gtaatccaca ggaaaaactc aaactccttg
    32281 cctttactgg tactaagggt aagacaacag cagcctattt cgcctataac atcttatctc
    32341 aagggcatcg acctgctatg ttgtcgacca tgaacacaac tcttgatgga gagactttct
    32401 ttaagtcagc gttgacaacc cctgagagta ttgacctctt tgacatgatg aatcaggctg
    32461 tgcaaaatga ccgtacccac ctcatcatgg aagtctccag tcaagcctat ctggtcaaac
    32521 gtgtctatgg tctaaccttt gatgtgggag ttttcctaaa tatcagccta gaccatatcg
    32581 gcccgattga acaccctagc tttgaagact atttctacca caagcgtctc ttgatggaaa
    32641 atagccgagc agtcatcatt aacagtgaca tggaccactt ctcagtcttg aaagaacagg
    32701 ttgaagatca agaccatgat ttctatggta gccaatttga taaccaaatc gagaattcca
    32761 aagcctttag attttcagct acgggtaaac tcgctggaga ttatgatatc caactcattg
    32821 gcaacttcaa ccaagaaaat gcagttgctg ctggacttgc ttgtctccgt ctcggagcaa
    32881 gtcttgagga catcaaaaaa ggcatcgctg caacccgcgt tcctggtcgt atggaagtcc
    32941 tcactcagaa aaatggagcc aaggtcttca tcgactatgc ccacaatggg gatagtctga
    33001 aaaaactcat caatgtggtt gaaactcatc aaaccggaaa gattgctctg gttctgggat
    33061 caacaggaaa caagggagaa agtcgtcgta aggactttgg cctcctcctc aatcaacacc
    33121 ctgagattca agtctttctg actgctgatg accctaacta tgaagaccca atggccattg
    33181 cagatgaaat tagtagctac atcaatcatc ctgttgagaa gattgcggat cgccaagaag
    33241 ccatcaaggc ggcaatggct atcacaaatc acgaattaga tgcagttatt attgcgggta
    33301 agggagccga ttgttaccaa atcatccagg gcaagaaaga atcctaccca ggagatacag
    33361 ccgtcgcaga aaattattta taagaataga aaaaatcaag ggaaaatgaa acccttgatt
    33421 ttttcctatt atttagtaaa aacgtttttc aaaccttcaa cggcaccttc tacagcacct
    33481 tttgcgtctt ctacaacgtc ttttgcctta gcaactgttt tttcaacagc tccttcaagt
    33541 tctgtcttgc tgtctccagt aactttacca aaaccttctt tgacagcgcc tgttgcttgt
    33601 tccaatttgt tttcaagtga catatgattg tctcctttag tttattccga tatgtgttac
    33661 cggttacata tagtttatac cgaatactaa ggaaagtcaa acaatgtact cagaaacaag
    33721 aaatcacgct aagtagaaag ttaatctctc cttatcaaaa tcgatagcca actcatactt
    33781 tccatcttca ttttgcacaa tatagcctaa gacaaccaaa ctgtccacaa agatatcacg
    33841 gcatttctgc ataagctggt cttttttgag aaatttcaac aaaaaagccg tcatatactt
    33901 gagtgcatac tcaggattaa catctcctaa aatgtcatag agctcctgct gtttttctgt
    33961 caaaggatac tgctgtttga ccttgtaaaa ataattggac agggtcattt taatgcgcgc
    34021 aaagtccgtc ttttcaacta aaatagctgc attgatttga ttgcgcaatt ccgtctcaaa
    34081 actctgctcc aacaaggctt gatagaccgg actagcttct ctgacaaaaa tctcttgatc
    34141 cagttcaaga ctatcaagtg attcaagcgt aggaaaattg aggtaatagc gcttattttc
    34201 acgtagaatc aagcctgcct ttatatactc ttccatgagt ttatcaactg caacatctgg
    34261 aaattgagcc ttaatttccc gtagaatcac atcctcatac tggtccagat agcggatcaa
    34321 ttctccaaaa atggctgtct cgtcaaacga gatggattaa aaatctgaat catgaagatt
    34381 cctttcttta cattgtaaca gaggcgatgc tgccaactga ctaggattgg taccagcttg
    34441 gttcagagga acaggcagac ctagttctat gtaatactcc ctccaaaaat cactaatctc
    34501 ctgctcccca tctccaaatt tcataggaat agtttcaaaa ataggtagga tttctgctat
    34561 atactgggag cagtagaaag cagctgcatc tggatagaaa gaagcattgt agggtgctcc
    34621 aagatgtctg caagctcttt ccttcaccga ctggatatcc atttctgggt aaacatagag
    34681 gtcgtataaa tgattggact caaagaagtc tgccggttct tgacagacaa caccagcctg
    34741 tccactagca tgataaatca tcccatccaa ataaatggca acatggctat agttacctgt
    34801 ggaagtctgg atggcctgtc ccatgtctga cccatctctc acaaaaatca aatcgccatt
    34861 ttctaacata cttcactcct agaaaaaagg agccgaaact cctttcgata taaggcaaac
    34921 tagactttcc gattttgagc tgacacccaa aatcttacgc attaaagctt tcagtcaatt
    34981 gaggtaccac ttgtttctta cgtgaaacgg caccagcaag gaaggcatga ttgttttcaa
    35041 gtttgaagtt gaaagccgct tcgaccttgt ccatattggc accaagagcc aagatttctg
    35101 agtttgagtt gacgatatct gtaatcatca agacaaagtc agagtagccg tttgattcgt
    35161 tggcagcttg cattgcagct tcaatttctg cttggcgttc caaaacttca gcgatgtcaa
    35221 ctgtgttcac ttgggcaaca cggacattat ttccgttgag ttcaaaagtc ttagcatcga
    35281 tatcaatcaa ttcttcagca gatttgctag ccaagttggt accagctttc aacattgcca
    35341 aaccatattc ttccaagttc acaccagcca attcagccaa ttcaggagca atgattttat
    35401 ctgttgggtg tgttgttggt gatttcaaaa gaagggtatc tgaaatcaaa cctgaaagca
    35461 tcaaacctgc aatctcttta ggcacagcta caccatgttc tttgaacata cggtaaacga
    35521 ttgaagacgc tgatccaact ggctccaaac gcatgtaaag tgggcttgca gtttcaaagt
    35581 tagccacacg gtggtggtct acaacaccgt aaacttctac ttcagcgata tctgatacag
    35641 attgttggaa ttcattgtgg tcagtcaaga taacttgctc tgccccctct gctttggcag
    35701 aagtgataac acgtggtgct tccacaccaa aatagttcaa gacaaaggct gtttcttcat
    35761 ttggagttcc aagggcaaca gcttccgtat ccaaaccgta agcttctttt gcaaggtagg
    35821 caaaagctac agatgatccg atggcatctg agtctggatt ttggtgacca aatactagaa
    35881 tcttggacat gataatacct cattttgttt attttcttta ttgtagcatt tttttcgctt
    35941 tttgacaaag gtaagaggag tcaaaggact ccccacgatt cttcaaaata actgagtaaa
    36001 tttctatctt gattttcaga taaaaattct tccttctgtg gcctcttctt acgcttgaga
    36061 agagcttcag ccgacatggc ttcttcctta ctggcaaaac cttgagcata gataagtttg
    36121 actggcaagc gtgctcgtgt atatttggct cccttcccac tattgtggat agcgaggcgt
    36181 cttctcacat cagtcgtata gcctatatag taggatccat cacgacactc cagaacgtac
    36241 atataagcct tatgatccat aataaatctc ttcgatttcg ggcgtataag agccatcatc
    36301 attgtggaca atcaaaggag gtaagacctt aaagccactt gttgagccat ccttgatcgc
    36361 ctcaatcaaa agcatattgg cttccttttc tctttttgga taaacaaact gcaggcgctt
    36421 aggggctaga ttatgtcgtt ttaacgtatc caaaatatcc agaagtcgat caggacgatg
    36481 aaccatggcc aaacgcccat tagacttgag aatactctgg gcactacgac agatttcttc
    36541 caaattagtc gtgatttcgt gtcgagccaa gagataatgt tcactctcgt tcagattaga
    36601 ataaggatcc accttgaaat agggtggatt acacaaaatc atatccacct tactcccctg
    36661 aatgtgagca ggcatatttt tcaaatcatc gcagatgacc tgcatttgct cctctaatcc
    36721 attcaaacgg acagagcgtt cagccatatc cgccaaacgc tcctgaatct caacagacaa
    36781 tatctgtgct tgagtacgag tgctagcaaa aagccccact gctccattcc cagcacagaa
    36841 atccacaatc aaccccttct taggaaaacg tggaaatcgt gataagagaa cactatccac
    36901 cgaatagcta aaaacctctc tattttgaat gattttgata tctgtcgaaa agagctggtt
    36961 aatgcgctct cctgatttta ataattgttc ttcttccatg gtcctattat agcaaattta
    37021 tattaacatc acaaaaaata taaaactcta aactacttcg tcttttttaa atggtgcagg
    37081 gcttctccag tccagattgg taacattcgt cgaaagggag caaaaccgta gttaaagcgg
    37141 tcgcttgaaa agcgtctccg tctaggaaac tggtactttt cttcctccaa agtgcggata
    37201 gaaagactgg ctttccccgt aaattcatct aaatccacta cctgaacttg aacctcttca
    37261 tcgactttca aggtttcatg aatattttca ataaatcctg tccgaatttc tgaaatgtga
    37321 atcagccccg tatcacccgt ctctaactca acaaaggcac cgtagggctg aatccctgta
    37381 atacgcccct ttagcttatc accgattttc atcttagtcc tcgatttcaa tagtttcaat
    37441 tacaacatct tcaactggct tgtccatagc tcctgtctca acagcagcaa tggcatccaa
    37501 gacagcgtaa gatgcttcat cagctaactg accaaaaacc gtgtgacggc ggtctaggtg
    37561 aggtgtccca ccttgattgg catagatttc tgcaatcggt tctggccaac caccacgagt
    37621 aatttctttc ttagaataag gtaggtgttg gttttgcacg ataaagaact ggctgccgtt
    37681 ggtatttgga ccagcatttg ccatggaaag agcaccacgg atattgtaaa gctcttctga
    37741 gaattcatcc tcaaaagatt cgccgtagat tgactcgcca cccataccag ttccagttgg
    37801 gtctccacct tggatcataa agtccttgat aatacggtgg aaaatgacac catcatagta
    37861 gccatctttt gaaagagata caaagttagc cactgtttta ggagcatgtt cagggaaaag
    37921 cttgatacgt aagtctccgt gattggtctt aatagtcgca agaggacctt ctactgtttc
    37981 aatgtctact tgtggaaaat gcaattcttt ttctaccata ccaaatactt ctaaggcatc
    38041 aaaaatgcca tcttcttcta atgtttttgt aatataatct gctttttctt tgattttatc
    38101 atgagaaatt cccatggcaa cgctgattcc agcataatca aagagttcca agtcgttgag
    38161 accatctcca aaaaccatga ccttctctgg tttcaagcca aggtgttcca caaccttttc
    38221 cacccccgtc gctttggagc ctgaaatcgg cacaatatca gacgaatgtt gatgccaacg
    38281 aaccatgcga agtttgtctg agagactgtc aggcaagtgc aagtcatctc ccttatcttc
    38341 aaaagtccac atctgataga tatcttcttt ttcatggaaa tcgggatcta catctaagtc
    38401 gggataaatt ggattgatag cttcactcat catatcggtg cgagtcgaca acttggcatc
    38461 atgactccca accaagccat actcaattcc ttcttgctta gcccaagaga tatactcctc
    38521 aacatctgac ttttcaatct gatgctgata aatgacctga ccttttttat cttcgatata
    38581 agctccattc aaagttacaa aaaagtcagg cttgagatca cgaatctctg gaacaacacc
    38641 aaaaatgcca cgtccagagg cgattcctgt taaaattcct ttttcacgca actgtttaaa
    38701 aacagtggga attgtagttg gaataaaccc tgtctttgaa ttccgcaatg tatcatcaat
    38761 atcaaaaaag acaatcttga tcttctttgc cttgtatctt aatttcgcgt ccatctcact
    38821 acctctttca atctaactct ttccattata tcataaagta ggcaaatccc ctattttcaa
    38881 aaagtttatc atttttattt taatttcttg gatgagaaaa aagacatatt tatgaaaaag
    38941 ctccatcgtg cttttaatgt gttctcttgt tttcaaactc gtaaaaaggg agccactgag
    39001 cctgactcgc tctctcattt caaagcttgt gaaaaaagac ccgttggggt cttaattcgc
    39061 tttcttgttt tcaagctcat gaaaaagaga cccaaccggg tcttttcttt aatcttcgtt
    39121 tacgaaaggc atcaaagcca ttacgcgagc gcgtttgata gctgttgtta ctttacgttg
    39181 gtttttagct gaagttcctg ttacacgacg aggaaggatt ttcccacgtt ctgaaacgaa
    39241 acggctaaga agctcagtat ctttgtaatc aacatattca attttgtttg ctgcgatgta
    39301 atcaactttt ttacggcgtt tgaatccgcc acgacgttgt tgagccatgt tttttctcct
    39361 ttataagttt agttgtccat tagaatggta aatcatcatc tgaaatatcc aatgggtttg
    39421 ttgctccaaa tggattttca ttacgtgaaa agtctggtac tgaatttgta ggtgctgaat
    39481 agtttgcagt tggtgcagag taagctccac ctgtgtgacc ctcacgcaca ctacggcttt
    39541 ccaacatttg gaaattctca gccacgacct ctgtcacgta gacacgttgt ccttgctggt
    39601 tatcgtaact acgagtctgg atacgacctg tcaccccgat aagtgagcct tttttagccc
    39661 agttagcaag attttcagcc tgttggcgcc acataacgac attaataaaa tcagcctcac
    39721 gttcaccatt ttgactctta aatgtacggt ttactgcaag agtaaaagtc gcaactgcta
    39781 catttgatgg ggtataacgc aactcagcgt cacgtgtcat acgccctaca agtacaacat
    39841 tgttaatcat agtttacctt cttacgcgtc aattttgacg atcatgtgac gaagaatgtc
    39901 agcgttgatt ttggaaagac ggtcaaactc tttaagagct gcatcgtcat ttgcttcaac
    39961 gttaacgatg tggtaaagtc cttcacggaa atcttggatt tcgtatgcaa gacgacgttt
    40021 ttcccaagtt tttgattcaa caacagttgc accgttgtca gtcaaaatag agtcaaaacg
    40081 tgctaccaaa gcgtttttag cttcttcttc aatgtttgga cgaatgatat aaagaatttc
    40141 gtatttagcc attgatatgt tcctcctttt ggtctaatga ccccaagact ttgcaagggg
    40201 taagtgaggt tcgctcacaa taaactatta tactagaaaa aattttttta cgcaagtaaa
    40261 aacactagaa ttcgaaaaaa cgccacatgg gcgttttcct gttcttatgg tttgatacgg
    40321 tgcaacatac gtgggaatgg aatagcttca cggatatgtt ttattcctgc tgcgaaggtt
    40381 accatacgtt cgataccgat accaaatcct ccgtgtggaa ctgtaccgta tttacgaagg
    40441 tcaaggtaga attcatattc tgtacgatcc atgccaagtt catccatctt agcgacaagg
    40501 gcatcgtaat cttcctcacg catagaccca ccgataattt ctccatagcc ttctggagca
    40561 agcaagtctg cacaaagcac gcgctctgga tttccaggaa ctggtttcat gtagaaggcc
    40621 ttgatggctg ctggatagtt catgacaaat gttggcacac caaagtggtt tgaaatccaa
    40681 gtttcgtgtg gtgacccaaa gtcatcacca tgctcaagat gctcgtagtc agcatcttca
    40741 tcattttcat gctcttgcaa gaggtcaatg gcttgatcgt aagtgatacg tttgaatggc
    40801 tctgcaatgt agcgtttcaa gagttctgta tcacgttcca aggtttccaa ggcttgaggc
    40861 gcgcggtcaa gaacaccttg tagaagagct ttcacataag cttcttgcaa gtcaagcgac
    40921 tcatcatgtg tcaagtatga gtactcagca tccatcatcc agaactcagt caagtgacgg
    40981 cgtgtttttg atttttcagc acggaaaact ggaccaaagt caaagacacg accaagagcc
    41041 atagcccctg cttctaggta aagctgacct gattggctca agtaggctgg cgttccgaag
    41101 tagtcagttt caaagagttc tgtagaatct tctgccgcat ttcctgaaag aattgggctg
    41161 tcaaacttca taaaaccgtt cttgtcaaag aactcataag ttgcatagat aatagcgtta
    41221 cggatttgca acacagctac ttgcttacga gagcgtagcc acaagtgacg gttatccatc
    41281 aaaaagtctg ttccgtgttc ttttggtgtg attgggtagt cttgagattc accgatcact
    41341 tcgatgtctg tgatgtccaa ctcatagcca aatttagaac gttcgtcctc tttgacaata
    41401 cctgtcacat aaacagacgt ttcttggctc aagcgtttga taacatcaaa cttctcaagt
    41461 cccacttctt caccaaattt ttcgacaaag tttggtttaa aagccacacc ttgaaagaag
    41521 gctgttccat cacgcaattg taagaaagcg atttttcctt ttcctgattt gttggcaacc
    41581 caagcgccaa tcgtcacttc ctgaccaaca tagtctttta cgtcaataat cgttacacgt
    41641 tttgtcatta tttttccttt tcttttttat tctttatggc aaaccacctc tatattgttc
    41701 ccatccaggt caatcataaa agcagcatag taaatcggat gctcacttcg ataaccagga
    41761 accccattgt ctcgcccact tgcctctatg ccagcctcat aacaagcctg aacttcttcc
    41821 ttattttctg ctaaaaaagc aaaatgaaca ggatcttgtg ttccctgagt cagccaaaaa
    41881 tcaccaccag gatgagggct gttcggggat agaaaactaa ttagagaact agtcttaaaa
    41941 gccaatttat agtccaaagg aacgagaaaa ctcctataaa atccttctga aatttgtaaa
    42001 tcctttacct taatctcaaa atgatcaatc attctcacta cccataaatg ctttcaagcg
    42061 ttcgactgct tctttaagcg tgtctaggtc tgtcgcatag ctgaggcgga cattttctgg
    42121 tgctccaaat ccagctcctg ttaccaaggc cacttcggct tcttctaaga taacagttgt
    42181 aaagtctgtc acatccgtgt agcctttcat ctccatggcc tttttgacat ttgggaagag
    42241 atagaaggcc ccttgtggtt tgaccacttc aaatcctggc acctctgcaa ggaggggata
    42301 gatggtatta agacgttcct caaaggcctg acgcatgctt tctacagtat cttgctcacc
    42361 tgatagagcc tcaactgctg catattgggc tactgctgac ggattcgaag ttgtttgacc
    42421 tgcaatcttg gacatggcag cgataatgtc tgcttctcca acggcataac caatccgcca
    42481 accagtcatg gcataggttt tagacacacc attgatgacc actgtttgct tgcgaatcgc
    42541 ttccgatagg ctagaaatcg gtgtgaactc atgaccatta taaaccaagc ggccatagat
    42601 atcatctgct aggatgagaa tatcgttttc tacagcccag tttccaattg ccaagagttc
    42661 ctcacgggtg taaatcatac ctgtgggatt agatggcgaa ttcagcacca aaaccttggt
    42721 cttgtcagtg cgagctgctt ctaactgctc tacggtcacc ttaaagtgat tgtcttcctt
    42781 agcagaaaca aagacgggaa cgccttctgc catcttgacc tgatctccat agctaaccca
    42841 gtatggggtt gggatgatga cttcatcacc tggattgacc acagccataa agaagctata
    42901 gagagaatat ttggctcccg cagcgactgt cacttgattt gacgctacag aatagccgta
    42961 aaagcgctca aagtagctat tgaccaccgc cttaagctct ggcagacctg aggttactgt
    43021 ataaaaagaa gcacgcccat ctcgaatcga tgcaatggcg gcatcttgga tatttttggg
    43081 agtagtgaaa tctggctcac ccaaggttag agacaaaata tctctaccct cagccttcag
    43141 tgctttggca cgggctccag cagccaaagt cacactttct tccatttcta aaacacggtt
    43201 ggatagtttc ataggccctc cttgttgacc aatgctcctg tttcaaaatc tactagataa
    43261 aaatcagatc ctgacttaac ttcccagatt ggcttatctt gataacggcc aaaggttatc
    43321 ttgtcaatct cgccagctcc cttttcctta gaaaccgttt ctgctttttc ttgtgaaaca
    43381 ccctgattta gctgataaac gtaaatctta tggtcatctt taccaatcag gacagcaagc
    43441 gcttcttgct gtttgttacg accaagaacg ctgtaataag attccaagcc attgtataaa
    43501 tcaacctgat cagcctgctc taatcctgca tactgctgag ctaatttttc tccttcactt
    43561 ttagctgttt gatagggttt catgctaaga gaaaccatat acagaaagga agcactgata
    43621 accacaaaca aaatcgtcat ccctagacca tactgccaca gtagattatt ttttgctttg
    43681 ttttgtcttt ttttcactcg tctattttac catctattaa gctttattac aagtgaatat
    43741 aagaatactc ttcgaaaatc tcttcaaacc acgtcagctt tatctgcaac ctcaaagctg
    43801 tgctttgagc aaccaattct atttctccct tcaaacaaaa ccgattttga aagtgaaaca
    43861 gttcttactt tttcagtcac aaatgattag agtttccgaa attttacaat tttcaaataa
    43921 actctgagca aatttcttgc aagttctttt gttttgttgt aatatatttt ataacaacga
    43981 gagagttctc gaaattttaa gaaaaaggag acacatcatg tctaaaaaag tattatttat
    44041 cgtcggatca ctacgtcaag gttctttcaa ccaccaaatg gcgctcgaag ctgagaaagc
    44101 acttgctggt aaagcggaag ttagctacct tgattattca gcccttcctc tcttcagcca
    44161 agatttggaa gttccaacac atccagctgt agctgctgct cgtgaagcag ttctcgttgc
    44221 ggatgctatc tggattttct ctccagtcta caacttctct atccctggta cagtgaaaaa
    44281 cttgcttgac tggctatctc gtgcccttga cttgtctgat acacgtggcg tttctgccct
    44341 tcaagacaag tttgtcacag tatcatctgt agccaatgca gggcacgatc aacttttcgc
    44401 tatctacaaa gacctcttgc catttatccg tacacaaggc gttggtgatt tcactgctgc
    44461 acgtgttaat gactctgcct gggcagacgg aaaattggtt cttgaagaaa cagtcctaaa
    44521 ctcacttgaa aaacaagctc aagacttggt cgaagcgatt cagtaaaaaa tagaaaattt
    44581 tagaaagtct aaatcaatta tagccaccta atagggtggc tttttatttc tcaatcaaga
    44641 ttttcagaca aacatcagcc atccaaaaaa aaccttgagc gttaccactc aaggttttta
    44701 gcagtctttt ccatcatagg aaaatcattc taagaatatt ctttcattcg agatctatca
    44761 cttatcatct tctttcgaga aattagtgac tgcttttggc tgattaatct tcttttcttc
    44821 gtcctacata taggctcaat agaataccgc tacctaaaag aacagagata taatcagatt
    44881 ggcttccagt ttcaggtaat ttgtccccac ggttttcttt acctgtagtt ggtgctactg
    44941 ggttagcatt tactggagtt gctggttgag ccggtgttgg tactactggt tgttctggaa
    45001 ccgctggtac tggtttaacc ggtacttctg gtgttgaaac agctggagtt ggttgtactg
    45061 gcacttctgg tgtcggtaca tttggtgttg gttgcgctgg cacaggttta accggtactt
    45121 ctggtgtcgg cacatttggt gttggaggaa ctggtttgtc atttgatggt gttactggtt
    45181 tgtcttggca tccacatttt ccatctttac cgtctttgcc gtctcgacca tcacgtccat
    45241 ctctaccatc tttgccatct ttaataactg tttttgtcac agttccatca gaattgatga
    45301 ttgtgattgt atgactacca tcaccattat cttcaacaga aacttttggt gatttaccat
    45361 ctttaccgtc tttaatcacc atttctgtct tacttccatc tggattagtg attgtaacaa
    45421 cgtgagttcc atcgttatta tttttaacag ttacagttgg tgaaacgcta tctttgccgt
    45481 ctttaccatc tttgataata gatttgtatt cacgaccatc agaatctacg attgttaatg
    45541 tatgagttcc atctccgtta tcaacgatgt tcgcttttgg tgatttacca tcaaagattg
    45601 tagttgtcgt tcctttacca tcagcacctg tcactttaat agtgtgtgaa ccatcgttgt
    45661 tatcaataac ttcaagtttt ggttctctac catcacgaac tgtagttgtt gtagttgttc
    45721 cgtctgagtt cacaactgtg atagtgtgag ttccatctcc attatccaca accttagcag
    45781 ttggtgattt accgtcacga actgtggttt cagaaacagt accattaccg ttttccacac
    45841 gaatagtgta agtaccatct tggttatctc taactgttgc tactggtgat ttaccatctt
    45901 taatgattgt ttcagtagtt gttccgtcac catttagaac agagatctta tgagttccat
    45961 tttgttcatc agttatagtc acttttggtg atttaccatc acgaactgtg gtttcagttg
    46021 tcacaccttc tggatttgta ataacgattg tatgacttcc gtctccatta tcacgaacag
    46081 atgcggttgg agtacgtccg tcaacaccgt cacgtccatt cttaacaaca aactcattct
    46141 tagttccgtc tgggttagtg attgttactg tgtggcttcc atctggattt tcagtagttg
    46201 ttgctgttgc agctttaccg tctttaccat ctttgatgat agcgttggta acattgccgt
    46261 ctccatctgt aactttaaca gtatgagttc catcgttgtt atccgttact tcaactttag
    46321 gagtcttacc gtctttaccg tttttaacaa cagtttcttt agttgaacca tctggatttg
    46381 tcaccgtaat tgtgtggctt ccatctgggt tttctgttgt agtgatattc gcagttttac
    46441 cgtctttacc atctttaaca actgttgttg attcagaacc atctgggttt tgaactgtga
    46501 tagtgtgagt tccatctcca ttatcttttg tagtaatagt tggagctgaa ccatcacgtc
    46561 catctatacc gttataaata tctttactat ttaatacttt atcgacacct tcgtcgtata
    46621 ccccattgtc attaacatca tcataaactg taacacggat accgttacgc gttggagttg
    46681 cagcagcatc tgtatcgcgt ctaattcttg aaggtgaagt aatatcttct actttgattt
    46741 tcggtgcacg gccatcttta ccattcttac catcttttac agtgaaggtt actggatctt
    46801 tacctgatgt tgtgatagtt acaacagtgc tttggccatc ttgtccacgt tgagtagtga
    46861 ttgtaggagt ttgtccatcc tgaccggttg caccagtttt tcccttagca ccatcttgaa
    46921 caaagactgt agttggttgt gaaccatcat ggttatcaac agtgatttct acacctttat
    46981 gccctgcttc atctttacga acagctgtaa ctgtaggtga ttttccatct actccatctc
    47041 taattaccgc aagtggtttt tctggattta atggttgtcc tgggttagct ggatcttctt
    47101 ggtaaacttt agtttcttta ccatccttga cagtaagcaa tgatttacca tctcgtccgt
    47161 ccgcgccttt agcaccatct ttaatcattt ctgaacctag aagttcatca gttcctggtg
    47221 tatatttgcc gtcattgttt tcatctgtat agaatgtcac aattgtatga gatggatttc
    47281 cgttttttcc ttggacacga agtaaatcaa cttttggagt tttaccgttc agaccatttt
    47341 ctccgtcctt aacatttact gtaactggat ctttacctgg aacagtgaat gtaatgtcag
    47401 tactatggcc atctttacct ggagttacag ttacttctgg agtcttacca tcttctccgc
    47461 gttcaccttt gtcaccctta gggcctttga tgttgccctc tttatcccag ttgccgttat
    47521 tcttaacgaa gacgtcgcct gtttctgtat taacgtattt atcgccgtct ttaccttgat
    47581 gtgcttctgg gttagctttg ccgttcaaca cgtctttacc gtcacgtcca tcacgaccta
    47641 ctgcgccatc cgcaccttta gctccttgcg ctccagttag gccgcgttcg ccttggtctc
    47701 ctttttcgcc tttagcacca tctgcacctt tgtccccttt agggcctttg atgttgcctt
    47761 ctttatccca gtttccattg tttttaacat agacatcacc ggtttcggta ttaatatatt
    47821 tatctccatt tttaccttgg tttggttgtg gatttacttt tccgtttaat acatctttac
    47881 catcacgacc tgcttgtcct gtagctccat cacggatcgt agttgtcaca tctggacttc
    47941 ctggattatg aaccgttaat gtatgtgtgc cgttttgccc ctcagttatt gttactgttg
    48001 gggttttccc atcagcaccc ttttgtccat cctctacaaa tgttgtttgt ggacgacctc
    48061 ctactggtgt aattgttact aatacaccat ttttgccatt ttgcacactt cgtgtcgctg
    48121 taattgttgg tgattgtcca ttagtaccgt ttcttccatc agtgatagtt gctaatggtt
    48181 ggtttggatt aagtggttgt cctggtctag ccggatcctc tacatagact tttgtttcag
    48241 ttccattttt aacagcaatt agagattttc catctttacc tggagttcct ggattacctt
    48301 gttctccttt tggtccttgt ggtcccgctg gtcctctttg tccatctgcg ccttttggtc
    48361 cttgagctcc atcacgacct tgaagacctt gttcaccttt gtcccctttt tcacctttag
    48421 caccatctgc aattacaact tcttttaatt tcttatcaga agcatctaat tcattgtttc
    48481 catttttatc gtaatagaag ataacagttg ttgtcttatc tgcgtcattt cgttgagtcg
    48541 caactaatgg acttgcgcca tcgaaaccat ctcttacaac agtacttgta acattacctc
    48601 taccgtcgtt aatagtgata gtatgagtgc cgtcattttt attatcttta acggttacgg
    48661 ttggagttac accgtcacga cctgcctgac cttgggctcc tttttcacct ttagctccag
    48721 ttaaaccacg ttcgcctcgg tctccttttt caccttgggc tccagtgaga ccgcgttcac
    48781 cttggtcccc tttttcacct ttagctccag ttaaaccgcg ttcaccttgg gctccttttt
    48841 cacctttagc tccttgagct ccagttagac cgcgttcgcc tcggtctcct ttttcacctt
    48901 tagctccttg agctccagtt agaccgcgtt caccttggtc tcctttttca cctttagctc
    48961 catctttaat agcaattttt tgaacaagtt cgtctacacc ttcagtataa acaccgtttc
    49021 catcgttatc aagatagaaa gtgaggttat ttgtatcacc gactttattt tgatcaacac
    49081 gtggttttac tgtatcgatt agatctttag ccacaccaat ttgcataata cgtggcttag
    49141 cttctttagt aacactatta ctaatcggca atcctaaaag tgtttcgtta ccaaatcgat
    49201 gaactttata ggtaatttga cgttgtcctt tttcaccttc tcgaactaat ctagtttgac
    49261 cttctggtaa cttactagtt ggaagataga cagtttggaa gtcaatgtct tctgaaacag
    49321 tcttattatt agtaccacca taagggtttg catccaagta tagtgggttt gctctataat
    49381 aatagttaga gttactgtat gggtcattgc tagtagcggc accaccacca ccttggtcca
    49441 cgttaaaagt aacaggtttc aaacgaacag acaaatcacc atttagatta atgataggca
    49501 aactaaatct gatagtttgt tccgtatttg ttgaaatagc agaggtcata ctgtatcctg
    49561 agtgagatac gtagttggca ccctgactaa tagattttga ttgctccctt actcttggat
    49621 ttgaacttgt gatcgttgca tttgaaggat ttccaaatcc atccccttta tccaagataa
    49681 aattattatt aacaaactct ctagaatctc ctggcgcaga ataactaatt gtaaagttaa
    49741 cactattacc actacgtact gttgttacat cgtaatgaat agaatttcca ccacgtgagt
    49801 tcccgtagcc acggaaacta tagctacgac caccttggct aatatctgca aatgcaactg
    49861 tatttccaga acctgagaca attgggttgg ctggattgct agccgctcta aaaccactat
    49921 accctctatt aacattttcc ttacggatag ctggattttg gcgagcatca gaaaggctca
    49981 aacctagttt caagatttca ttaatagatg ctggagctga agttgtttct actttgtcag
    50041 ctgtgctagt tggcaaaata gcgctatcaa cagctgaacg ttcagttgtt gcagctggtt
    50101 tagccccttc ttttgattca actgcatcag ctttcttcgc tacaggcgtt tctgatacag
    50161 tttctttatt agagttagaa cgaagttcta gaccaataat aaatgattga atagatgact
    50221 ctgctgctga taattcagct tcagttgcat ctgcttttcc aagcaagctt tgaccagctt
    50281 ggatacttgt ttgcaagtta gcagcacttg cttctgtata taacttgctt tctaattttt
    50341 tagcacgcga aagagccgtt aataattttg acttgtcaac ggcatcttga tgcgttactt
    50401 cctctttttt gtcttttgct tcttcaactt tttctgctgg tttagtaact tcttcagttt
    50461 taactggagt cgtttctact ggattagcta cagttggagc tgcataggtt ttctctttat
    50521 tagacgcaga aacctctgct ggtttagtag ctgcttctcc cctaccaaca gaaatactat
    50581 tggtagtttc ttgtttgttt tcttccgctt gtactgtttg gacactagct gctacaccta
    50641 ataccaaagc ggtaccgagc aagacactag ctgcaccaaa gtaatactta cgaatagaat
    50701 aacgttgttg catgctatac cagtcaaatg attttttatg tgaatgtttc attttaaact
    50761 cctagatagt attttatagt ttacaatgta caactatttg aggcattaat caatattttc
    50821 tgaacaatta atatactctg tttctgcact taaaagccac ttatattatt ctaatttttc
    50881 cgattactaa cgacaatttt cttgctctaa tttttttata ctacttagac aaaaaaagat
    50941 ataatgaatt atggaggaaa tacccgtatg agaaaccttt tatccacaaa agttcaaaga
    51001 caattacgct taatggaaac cctaattcag aatcgtaatt ggatgaaatt acatgaacta
    51061 gccgaaaaat taggatgtac agaacgaatc ttaaaaagtg atttaaatga attacgtatt
    51121 gcctttccat ctattaacat ccaatcttct gttaacggaa tcatgataga tttagaagtt
    51181 aacactagtg tagaagatat ttatcaatat tttcttgcta attctcaatc ttttcaatta
    51241 ctagagtata tgttcttcaa tgaggggcta cctatttatc gaacaataga aaatctttac
    51301 tttagtagtg ccaacctcta tcgactgggc agaaatatta caaaggttct ttcatctcag
    51361 tttcaaattg aattatcttt tactccatcc gagatacgtg gaaatgagat cgatattcgt
    51421 tacttttttg cccaatactt ttctgagcgc tattatttcc tagattggcc ttttcctgac
    51481 cttcctgagg aagatttaac agagtttgct gacttcttct ataaaatcac gaattatcca
    51541 atgcgatttt caatttatag aatgtacaaa ctgatgatag ctatcagtat ccacagggtt
    51601 aaaaatggtc acttcattga cctccccaac cacttttaca aagaatatta tcctctttta
    51661 aagagcattc caaatttcca ggagacactt gcttatttct ctaaacattt tgggcttgaa
    51721 atgactccag atacaatcgc tcaaattttt atttcttttc ttcagaatga tattttccta
    51781 gatcctcaag aattcttcaa ctctttagaa gataacagtc aagcaagata ctcttatcaa
    51841 ttacttagtc aaatattaga actcctatca aaacaatata agattacttt tactaaccac
    51901 gatgagctga tttggcattt acacaacact gctttctttg aaagacagga aatcttttct
    51961 accccaatct tatttgaaca aaaagcattg acgattaaaa aatttgaagt ttacttccca
    52021 gactttatgg gaagtgcgcg tcaagaactg gctcaatacc gtcaggcaat tggacagcat
    52081 gaccatcctg aacagttgga acacttgatg tacaccatct taacccatgc tgaaaacctc
    52141 tctactcagt tgttagaaaa tcgaccacct atcaaggttt tgattatcag taactttgac
    52201 catgctatat cccttacctt tgttgatatg ctttcctatt actgtaataa ccgctttacc
    52261 ttcgatattt gggatgaatt aaaaacaagt cctgagattt taaatcagac agattacgat
    52321 atcatcgtgt ctaatttcta tatttcaggg attaccaaga agtttatttg ccgaaatcat
    52381 ctgtcaatca tgaatttggt taatcatctt aacaccttat caaatgagat tcatttgtcc
    52441 aatactttat aagttatcaa aaaagtcagc ataatcgtgc tgacttttct cttatctgat
    52501 ttctatactt cctttacaaa aaccaatccc tgtggttgtg acaaatcttc tcggtaaaca
    52561 aatccagcaa agttcaagcg acgtgcttcc cccacagttt gtacttgatt ttctattaaa
    52621 gctgttagaa aggccccgcg cgctttcttg gagatagttg agtgaatctt cagctgaccg
    52681 cctctatcct ccatgaattt gaaggtcacc atctttgctc tgatttcctt agaaaataca
    52741 gtctcaaact ctgatgacaa gagagagaaa atcacttctt ccttcttcag agcttcatca
    52801 tagactgcct tccaatggct cttcaaagtc ttaccagcga cttttaattt catcaaaaaa
    52861 tccaaacggt gaggagccat gggtgacaag gctggaacaa caccgtacaa agccgaggta
    52921 atgaagacat gattttcaag ataatcttgt tccgcctcgg tcagcttatc tctcttaatg
    52981 ttgcggtaca taagcccatc aaaaagtttc aaggctggat agtgttgagc agtttgcctt
    53041 ttcaaagctt ggatattttg aaattcttcc gccgctttct cagctgatac cttgtagaaa
    53101 ctctccaatt gactggcaga atagagagcc aaggcatcaa gcacggtctg actttctggt
    53161 tttaaaggaa ttgcctcgat acttggcaag tctgtgttca tttcttttgc tgttgggatt
    53221 aaaattttca tattgatagt gtagcatatt ttttagccac aaccaagaaa ttcatttgaa
    53281 aaacctcggt ttgaccgagg tttttctatt tatttgggcc atcctaacca gacagccacg
    53341 agaacaaggg ctgtgccagc taaacttgtt aagatagata agaatttatc ttttttctcc
    53401 ttgaactgag aaaaacctat cttcaaagcg agcagtccga gtagcattga agcaaccatc
    53461 aaataaaaac ccatttcttt gtcctccatt agtcttaatt tactctatta taacatatac
    53521 tttctgaaaa aacctatttt taccgtagct taaaggtctt gagataattg tcttttccta
    53581 cttgaccttc gaaggtttta ccattttcaa ggtaaggaag atcatcggat actgaagcct
    53641 tgaccttgta tatcttgcca tcaactttaa agaagtagac agtgtctccc ttgataacag
    53701 ctgatttgag gtctgctact actcccttga tgctttctgt cgttgcattg tcaatttcaa
    53761 ggtcgttttt attggcatac ttgctgagca tctcttccac tgtagtagca acgataacat
    53821 tttggtactc gactgcgtct accagggcgt actctttgac caagccagca ttgtccttta
    53881 agcccatgat gtagagaggc ttgtcattga ggttgatgag gattgggaag gttgctttgt
    53941 aggatttctc ctgaacagca ccttctgctg attcacgggc tgattcttct gtcgcagaag
    54001 ccaagctata cttagtgatt tctcctgttc gcatattttc aaggatgaaa ccaagattac
    54061 tctcatccgc attagccgac gtcacacctg tgtagagata gatgtcatta ccgatagaca
    54121 agtaattata gcccttggta gtctgggtca cgtttttctt ggaaatcatg gcattcaaga
    54181 aaccgtcctt gtacttgccg ttgtagttaa tttgctcaat ggtttcctct gctggataga
    54241 tcctgtccac ccattctgga acatctgata agctgtattc cttggtttct ccatttgtag
    54301 catccaagat aatgactgaa gcaggacgag gaacagcaag tccaaattgc ttttggtaaa
    54361 ccgttgctac atagaaagga ttgccctcat cgtccacctc aaaagatgga gttttaaaga
    54421 ttttggtcgg gtacttcaag cgcaggtgac gtttgacatc acggttaaaa tactccgagt
    54481 ctgaatactt gattggtgtc ttcaagtcca ccaaatccgc atttccagtt accatgtcca
    54541 ccttgatata ctcaccgatt cccttggctt gattgttaaa ccatttgata gggtctgcat
    54601 attctagtgg tgtgacccga taaggtttcc catcaattgt caattgggta taggtatctg
    54661 ccgctacgta ttgcgacacc ttatcggtta gggaacccaa gtagcggtct ccaatttttt
    54721 cagcagtact tctatctagg ataggaacct tactggtgtc actcttagga aattcagtaa
    54781 agtctttttc cgtaaccgtg actacattgg cataattttt agcctgaaac atgctggaag
    54841 ttaccaagga aaccaaagct gccaagagaa gaattcctcc aatcgaagct aacagaattt
    54901 tccctaaccg attgattttg aaaccctcaa gatttaaggc agcttccgcc ttaccgtggc
    54961 gcacatgaac cgttttgaca aggtttatcc ccttgccaaa gccaaataag attgccacaa
    55021 ctaacaaatg cccacagagg aagaagagaa attcccagct ggtcaggtta aggggcggta
    55081 aaaagatata ccaggtcgtt gcgataaaaa taagttcaaa gactattcgt ttcatttgct
    55141 ttcctcctaa atgattcgtc cttccaagtg atccagctca tgctggcaaa tctgagctgg
    55201 gaagcctgtc aaggtaatgg tctgttcctg ccacttgctg tcacgatagg caacccttat
    55261 ggtttcataa cgcttagttg atctcacacc taccaaggac aaacagcctt cttctgcctc
    55321 ataggatcct tcaaaggaca gaagcactgg gttaaacatg accacgggaa ccaagccaag
    55381 attaaagata atcacgcgct tctgcacccc aatcatattg gcagctagac caacacaggt
    55441 atcacgattt gctaagagtg tatcctgcaa atctctggca agataaaggt cctcctgact
    55501 tgccggctga gacacttgag ataaaaataa gatatccttc acaattttct tttccacttc
    55561 ctcacactcc tcttgctttt tactatatta tagcaattat agcacaaaag ccgataactg
    55621 caaacccttt ccctcaactg tagcaaaaag ccatccgaag atgacttttt tgctatttaa
    55681 tttctgtata agttacttcc aagccacgct taacagctgg acgattggca attttttctg
    55741 cccattttac tagattttga taacttgagg catccaagaa ttttgcagaa ccttggtaaa
    55801 gatttccttg aactaactgt ccataccaag accagatagc aatatctgca atcgtatagt
    55861 cattgcctgc aatataaggt ttctgagcca attccttatc caataaatcc aactggcgtt
    55921 tcacttccat cgtaaaacgg ttaataggat attccaattt ttcaggagca taattgaaga
    55981 aatgtccaaa tcccccacct agaaaaggtg ctgcacctgc ttgccagaat agccaattca
    56041 aaacttctac cttttccaca ggattacttg gtaaaaaggc tccaaatttc tcagcaaggt
    56101 aaagaagaat atgagcagac tcaaagactc ttacgttttc agtacctgac tggtccaata
    56161 aggctggaat cttggaattt ggattgagct tcacaaagtc tgagccgaat tgatccccat
    56221 ccatgatagc aatcttatac aagtcgtaag ccgcttcctt aaaaccagct tctagtaatt
    56281 cttccaataa gatagtaacc ttcacaccat ttggtgttcc cagtgaataa agctgaaaag
    56341 cttgttctcc ttttggcaag ttttgttcga aacgggcacc tgctgttggt ctgtttagcc
    56401 ccgtaaaagc tccttgatta ctagcttcat cctgccatac ggtcggtaat tgatatgctg
    56461 acatccgaaa cctcccttaa atcgcattct tgtcaaaacc gagtttgcgt tgaataaact
    56521 taacgatttc gacgatgata atcattgaga agcttccagc cataacaatt ccccattgtg
    56581 acaagtctag tttggttacg tggaagattc cttcaagcgg ttctacaacg attgttgcca
    56641 tgagaaggat aaaggatacc aagatggacc agttaaaggt cttagacttg aatgggccaa
    56701 ctgtcaagat ggattggtag acagacttga cattgtaggc atggaagagc tgaatcaaac
    56761 caagggttgc aaaggccatc gttagggcat ctgcatgaat agcatgattg tcacccacat
    56821 gaactgggta agcaatcgca aggccataaa cactcataac aagagctgct tggagtacac
    56881 cttgataaat gatagaactc aaaacaccac ctgagaagaa gcttgccttg cgtccacgtg
    56941 gtttatgatt catgacacca ggttccgcag gttcaacacc aagagcgata gctgggaagg
    57001 tatccgttac caagttaatc cacaaaagat gaaccggctg taagacatcc caaccaaaca
    57061 aggttgatag gaagatggtt aatacttcag cagtattagc agaaagtagg tactgaatag
    57121 tcttttgaat gtttgagaag accttacgtc cttcttccac tgcgacgata atagtcgcaa
    57181 agttatcatc tgcaagaatc atatcagaag cccccttaga aacctctgta ccagtgattc
    57241 ccataccgat accgatatcg gctgttttca gagctggcgc gtcattgaca ccgtcacctg
    57301 tcatggcaac gactttacct tgtttttgcc aagccttgac gatacgaacc ttgtgttctg
    57361 gagacacacg ggcataaaca gagtattgac caacgacttt ttcaaattct tcatctgaca
    57421 gttcattgag ttcagcacca gttaaaacgt gaccttctgt atcgtttgcg tcaatgattc
    57481 ccaaacgttt ggcaatggct tccgctgtgt cttggtggtc acctgtaatc ataattggac
    57541 ggattcccgc ttccttagcc acacgaacag cctcagcggc ttcaggacgt tcagggtcaa
    57601 tcatcccaat caaaccagta aaaattaaat cattttcaag ctcttcagaa gtgagatttt
    57661 ctggaatact atcgataatc ttataagcac ctgcaaggac acgcaaggct tgatgagcca
    57721 tttcagaatt gtttgtatga atgagatttg taaccttctc atcaatcgga gcaatatccc
    57781 cagccttatc acgaagaaga caacgtttta agagttggtc tggcgcaccc ttgactgcta
    57841 caaggaaacg accatctggc aatgggtgaa ctgttgacat gagcttacgg tcagagtcaa
    57901 atggcaattc agctacacga ggatatttct ctaagaaacc tttgacatca tagcccttgt
    57961 ccaaggcata ttggataaag gctgtttcgg ttgggtcacc aatcaagtta ccttccacat
    58021 cgattttcgt atcattggcc aagacaactg aacgaagtag tggcatttca agacctagtt
    58081 caatatcatc agctgagtca tgtagaaccg catcgtagaa gactttttcg actgtcatct
    58141 tgttcatagt cagcgtacca gtcttatcag aagcgatgat ttcagttgaa ccaagtgttt
    58201 caactgctgg caacttacga acgatggaat gtcgtttggc caaaacttga gtaccaagag
    58261 aaagaacgat ggtaacgata gcaggaagtc cttctggaat ggctgcaacg gcaagggcaa
    58321 cagaagtcaa caactcacca agtggatttt tcccttgaat gaagacaccc actacaaaag
    58381 taacaagggc aatgaccaag atagcatagg tcaagacctt agaaaggttg ttcaaatttt
    58441 gtttgagtgg tgtatcagtc tcatccgcat cttgaagcat accagcaata tgaccaactt
    58501 cagtgtacat acctgtattg acaacaacac ccatcccacg accataggtt acgtttgagt
    58561 tttggaaggc catgttgaca cggtcaccaa taccagcatc tgtcgcaagc tcgactgaca
    58621 agtctttttc gactggtaca gattcacctg tcaaggctgc ttcttcaatt ttaagagagt
    58681 tggcttctat caaacgtagg tccgctggta ccacgtcacc tgcttcaagg gcaacgatat
    58741 cgcctggtac caattcttta gagtcaatct ctgccatgtg tccatcacga agaacgcggg
    58801 caactggact agacatggat ttgagggctt caatagcttc ttcagctttt ccttcttggt
    58861 aaacaccaaa ggcagcgttg atgataacca cagctaggat gataatggca tctgcgatat
    58921 cttccccacc agaagtcacg actgacaaga ttgctgccgc aactaggatg ataatcatca
    58981 aatccttaaa ttgctcgatg aatttgacca agattgatcg tttctcgcct tcttcgagtt
    59041 cattgtgccc aaattcggca aggcgctttt ccgcctcact tgatgacaaa ccttgctcgg
    59101 tcgcatccac agcctgcaag acctcttcag ggctctgagt ataaaacgct tggcgttttt
    59161 gttcttttga catgtgtctc ctccttgaca ttgtgtgcaa aacagactct ctttctgtca
    59221 tatcttttca cgacaaacaa aaagagacct gttaatcata acaagtctcg ctgtttaaga
    59281 tagggccgga aagcatactt ttcagcataa aattcggaat gacgacacta tcacaggttt
    59341 ctgccagcta ctcccttgag tagtaccatt ataccaaatt ttggggagtt ttcaaagagt
    59401 aaaaactgcc ttatttgaat ttttccttga aaaccagtat aatggtagaa tgctatgtga
    59461 ctagaaagga agttgaatga agcaatctat ctcaaatctc aagttagctg agcgtggagc
    59521 cattatcagt atttcgacct atttgatctt gtctgcagcc aaattagcag ctggtcatct
    59581 ccttcattca tccagtttgg tggccgatgg ttttaataac gtatcggaca tcattggaaa
    59641 tgtggccctc ttaatcggga ttcggatggc gcgccagcct gcagaccgtg accaccgttt
    59701 tggtcattgg aagattgaag atttggcaag cttgatcact tctatcatca tgttctatgt
    59761 cggtttcgat gttctaagag ataccattca aaagattctc agtcgggaag aatcggtcat
    59821 tgatcctctt ggtgcaactc taggaatcat ttctgcagcg attatgtttg tggtctatct
    59881 ctacaatact cgcctcagta agaaatccaa ctccaaagcg ctgaaggcag ctgctaagga
    59941 caatctttct gacgctgtta cctcacttgg aaccgccatt gccatcctag ctagtagttt
    60001 caattatccg attgtggata aactggttgc tatcatcatc actttcttta tcttgaagac
    60061 tgcctatgat atcttcatcg agtcttcctt tagtctttca gatggctttg acgaccgcct
    60121 gctcgaggac taccaaaagg ctatcatgga aattcccaaa atcagcaagg tcaaatcgca
    60181 aagaggtcgc acctacggta gcaacatcta cctggatatt acactagaga tgaatcctga
    60241 cttgtctgtt tttgaaagcc atgaaatcgc ggatcaggtc gagtctatgc tggagaatcg
    60301 ttttggcgtc tttgataccg atgtccatat cgaaccagca cctatccctg aggatgaaat
    60361 tttagacaat gtctataaaa aattgcttat gcgtgaacaa ttgatcgacc aaggaaacca
    60421 actagaagaa ctcttgactg atgattttgt ctatattcgc caagatggag agcagatgga
    60481 taaagaggct tataagacca aaaaagagtt aaattctgct atcaaggaca ttcaaattac
    60541 ttccatcagt caaaaaacca aacttatctg ctatgagtta gatggtatca tccataccag
    60601 tatctggcgt cgccacgaaa cctggcaaaa tatctttcat caagaaacca aaaaagaata
    60661 gagaaatcct ttcatgagac gggatttttc tattcgttta tactcaataa aaatcaaagt
    60721 gcaaattagg aagccggtca caggctgtac ttgagtcggc aatgtgaagc cgacatagtt
    60781 tgcactttga ttttcgaata gtcttaacta tcaaattcac tgagatactc atagcgttcg
    60841 tatttttcaa ggagtgcttc atttttctca tccaattctt tttggagagt agccagctta
    60901 ccaaagtcag agccgttagc ctgcatttcc tcttcaatag cagcgatacg tttttccaag
    60961 gtttcaatat caccttcaat acttgcccac tcctgctttt cttggtaggt catgcgtttc
    61021 ttgtcttctc gaaccttgac cactttttcc ttttcgacct tttgcacttg attggccata
    61081 tctgtttcaa aagctttttc atcaagatag tcggtgtaat gaccaaagaa aggacgaatc
    61141 ttgccatcct caaaagcgag aatcttggtc gctaccttat ccaagaaata gcggtcgtga
    61201 ctgactgtta aaacgggacc tgcaaaacct tgcaagaaat tctctaagac tgtcaaagtt
    61261 gcaatatcta ggtcattggt tggctcgtct aaaagaagaa catttggttt ttccaaaagc
    61321 agtttgagga gataaagacg ttttttctca ccccctgaca atttctcaat caaggttcca
    61381 tgcgtcgaac gtgggaaaag gaactgctcc agcaactctg caatcgaagt cgtagaaccg
    61441 ccactggtct tgacctcctc tgccacttcc tgcaggtaat tgataactct cttgctttca
    61501 tccaaaccct caatttgctg agagaaatag gcgatgcgaa cagtttcccc aatcacaact
    61561 tgtcctttag ttggctcaag acttcctgca atcaagttga gcagggttga ttttccaaca
    61621 ccattgtccc caacgattcc gatacggtct ttggcctgca ccaagagatt aaaatcttgc
    61681 aaaataggct tgttttcata ggcaaaggaa acagcctgaa actcgatgac tttcttccca
    61741 atccgactgg tttcaaagtt catggtcaag tctgtctcag cactactgcc tgaaactttc
    61801 tttttcagat catggaatcg attgatacgg gcctgctgct tggtcgcacg cgcctgcggt
    61861 tgtctgcgca tccaggccaa ttcttgtttg tagagttgtt cttttttgtg aagaagagcc
    61921 gcgtcgcgct catcctgttc cgcctttagg cgaacatagt cctggtaatt tccctggtac
    61981 tcggtcaagc ctgcacgatc caactcgaaa atccgtgttg acaaagcgtc taagaaataa
    62041 cgatcgtgag tgataaaaag gacggtcttc ttagaatttt tcaaaaagag ggtcagccac
    62101 tcaataatcg caatatccag atggttggtc ggctcatcca aaaacaagag gtcgtggttg
    62161 ccaagtaaga cttgtgccaa ctgtacccgt cttctcagac cacctgacaa ttccccaaca
    62221 ggagtagata agtcttgaat gcccaatttg ctaagaacgg tcttgacctg actttcgatt
    62281 tcccaagctt ggagagagtc catctctgcc atgacacgtt ccaaacgcgc ctgcttgtcc
    62341 tcactatagt cgagcataat caattcatac tcacgaatga gctggatttc cttgagttca
    62401 ctagatagaa ccgtatccaa aactgtcttt ctatcatcaa aatcaggatc ctgagtcaag
    62461 taaccaatct ggtaatcatt tttagctgaa aaaggactga catccccatc aaatccagaa
    62521 acaccagaaa ggacgtccaa aagggtggtc ttgccagtcc cattgacacc gattaaacca
    62581 attctgtcta agtcatggat aataaaggaa atatccctaa aaacggtctt gtcaccaacg
    62641 gatttactta gtttttcaac gataaaatca ctcatttttt ctccctcagg taagcatgga
    62701 tggcttcacg attattctcc aattctccat cgacaatggc aaactcaatc tctgttaaaa
    62761 tctctcccaa gtctgggcct ggctgatagc catattcctt gatcaaaata ccgccattaa
    62821 tctgaatctc tttcttgtca tggatagtca agctttggta tttttctgtg atggcttgtg
    62881 ggttgacttc ttttccttga gcttgacaaa gattttcagc ctgtaaaagc aaatctatgt
    62941 caaagcgata acaatctcgc ttgctcaatt ctccattttc acgcagagcc aaaataatca
    63001 gcaaatcctg aacttgcttg gcaaactggc gtgaggtctt ccaagatttc aaaaatgact
    63061 gcgcattttc aatctccaaa gcccatagta aagccgccca ggcttgttca gaggattcaa
    63121 aagtaaaatc agtctccaaa tcaaacagtc tgttgagctt gtcctggcta gatgccatat
    63181 cagggagata gtcataagct tgactctcaa tcatggaagc caagcccctt ctccaaaatg
    63241 gagccagcaa gagtttatca aactcgacga aggtacgctc tacagaaatg ttctccaaaa
    63301 gcggcgtcaa ggtcttcata gctttaaatg tttctggttc aagtgcaaaa ccaagactag
    63361 cctgaaaacg gaaaccacgc ataatccgta aagcatcttc gttgaaacgc tcactagcca
    63421 ctccaactgc tcgcaagact tgcttttcca aatcttctaa accatggaac aagtcaacga
    63481 tttctcctgt ctcatccaag gcaaaggcgt tgactgtgaa atcacggcgt ttgaggtctt
    63541 cttctagcga gcgcacaaag gaaaccgcac tgggtctgcg atagtccaca tagacatcct
    63601 ctgtccgaaa ggttgttacc tcatactcct catccccatc taagaccaag acggttccat
    63661 gctcgattcc gatatcggct gttcgcggaa aaatctgctt ggtctcttct ggataagaag
    63721 acgtcgcaat atccacatcg tggatagggt tatggagaag ggcatctcga acagagcccc
    63781 caacaaaata agcctcaaag cctgcttctt taattttttc taatactggt aaagccttct
    63841 gaaattcaga aggcatttgc gttaatctca taataagtgt tctaatccat agacaagctc
    63901 atgacgcttg acaacttctt taattcccaa attgactcct gtcatgaagg agatgcgatc
    63961 ataggagtca tgacggaggg tcaacccttc tccctgattg ccaaagatga cttcctgatg
    64021 ggctaccaaa cctggcaaac gaactgagtg gatgcgcata ccatcaaagt cagcaccacg
    64081 agcaccagca atcagctctt cctcatctgc tgcgccttgc tgaatggact ctcgaacctc
    64141 tgccatcaac tcagctgttt taatggctgt tccactcgga gcatcctttt tcttgtcatg
    64201 atggagctca ataatctcca catttgggaa atatttggca gcctgcgtcg caaattgcat
    64261 gagtaagaca gcacccaagg caaagttagg ggcaatcagg ccacccaagt cttgggcacg
    64321 agaaaattct tttagctctg caatttcttc actcgtgaaa ccagtcgttc caactactgg
    64381 agcaaagcca ttttcaagag caaaacgtgt attttcgtag gcaacagctg gagtagtaaa
    64441 atctacccag acatccgctt caaaaccagc taaatcagcc ttatccttga aaacaggaat
    64501 accctgccat tctgactcag actcaaaagg atccaaaact gccaccaagt ccaagtctgg
    64561 agcagtcaag accatctgac aagcagcctg gcccatcttt cccttaaaac cggcaataat
    64621 tactcgaata ctcatctcta ctcctgtcta agatacaaag tccgtaagaa cacaaagtga
    64681 aaataggaat tccaatcaag aagtgtctac ttcttggaag aactatcttt ttcacacagg
    64741 gttccaggcg tgttcaatta tcaagataca aaggacctta gctgcctctg aaaaataggg
    64801 aatggcactg actttccacg aaaggcaaga caggcatctt ttttcaagag gcaggtagtc
    64861 cgtgttcaat ttctaagata caaggcatct taactagcct agaagcgcca actaaatcac
    64921 tggaatataa cccagagcaa tacttcctgc tcctaggtgc gttccaatga cactaccaaa
    64981 tgtagcaagt gaaacatccg aacccaagcc aaaatcaagc aagtgctgac gcaattcttc
    65041 agccttttca ggagcattcc catgaatgac aatgacccgg tattgacctg aagccgttgt
    65101 ttccttgata atttcaatta agcgcttggt ggccttcttt tcagtacgaa ctttttcgta
    65161 aacttcaatc acaccttgat cgttaaaata aaggattggc ttaatgctaa gcaaattgcc
    65221 caaaatggca gccccatttg aaaggcgtcc accttttacc aaatgatcca agtcatctac
    65281 catgataaag gctgacgtac ggctgatttg aatggctagc ttatcctgaa tgctggcaaa
    65341 atcatcgccc tgatcacgcc aattaaagac gctttcaacc atgatgccta ggggagcact
    65401 tgtaatcaaa gtgtctggga aagcaatggt taagccctca tagtcatcga ccatatactg
    65461 gatattttgg taaaaacctg aaattccaga agataggaaa agccccaagg catgtgtata
    65521 gccttgttct ttgagcgaag ttaagatctc atctaacttg gcaatacttg gttgactggt
    65581 cttaggcaat tcagaagcct gagccatttt ttggtaaaat tcctcagcag acagattgat
    65641 gccttcgaca tattcctcac catcaatatt gacaggaata tccaagacaa acaagtcttc
    65701 tctttgcaag gtctcttcac tgagataagc agaggaatct gtgaaaacag ctaatttcat
    65761 attagaactc caaattaatt cctggtaagt ctaatgcaat ttcagtcact tcgtaagtca
    65821 aacgattgag catgttcaaa catggacgag ccaaggtttc cacctcttct tggttcaatt
    65881 catttggttc attgacaata cggccatcga tatggtttac ttgtgagatt gttccactaa
    65941 tgacaaactt atcaaataca atcataaagc tcaagatgac aatcaaggaa gtcacttgat
    66001 tttcttggtc atgttggagc aattggaaat tcacatccac cttggtttca ggagctccat
    66061 tttcattttc ccattcaaaa ttacgcgcat caaaatgata ctgactaaca aattcttgtt
    66121 cacgtttaag attcatgtct ttctccatcg gctacaatat tataagctat tgtaccataa
    66181 ttttttattt tcatctagtt ttctaggatt tagtcaatcc caatttcagc acgaactaca
    66241 tctgtgatgg tatcaacata gtagtctact tcttctgttg taggcgcttc tgccataaca
    66301 cgcaagaggg gttctgttcc acttggacga acaaggatac ggccgttccc cgccatttct
    66361 tcttccatct tctcgatgat ggccttgata gctggcactt ccatggcctt ttccttcatg
    66421 acgttttcca ctcggatatt aactaatttt tgtggataaa tcgttacttc tgccgccaac
    66481 tctgataagc tcttaccagt ttccttcatg attttagtca attgaactgc tgataattga
    66541 ccatcacctg tggtattgta atccatcaag ataacgtgac cagactgttc accaccaagg
    66601 ttgtaacctg attttctcat ttcttcaaca acgtagcggt caccaactgc agtaactgcc
    66661 ttgttaatac cttcgcgatt caaggccttg tggaaaccaa ggttagacat aacagttgtc
    66721 acaattgtat tttgagccaa ttgtcctttt tcagaaaggt attttccgat gatgtacata
    66781 atcttgtcac catcgacgat gtcaccattc tcatcaacag caatcaagcg gtcactgtct
    66841 ccatcaaagg ccaaaccaat agctgaccca ctttctttga ccacttcttg aagggcttct
    66901 ggatgtgttg aaccaacatt aaggttgatg ttaagaccgt ctggtgtttc cccgataacc
    66961 gtcaattggg caccaaggtc tgcaaagatt tgacgggcac tggtagaagc tgctccatta
    67021 gctgtatcca aggcaacctt cattccatca agaggagttc cagttgaaac aaggtatcct
    67081 tcatacttac gcaagccttc tggataatct accaaaattc ctaagccttc tgcacttgga
    67141 cgaggaagag tgtcttcctc agcatctagc aaggcttcaa tttctgcttc tttttcatca
    67201 tctagtttga agccatcacc gccaaagaac ttgattccgt tatcaagggc tgggttgtgg
    67261 ctagcagaaa tcatgacacc ggcacttgct ccttcagttt caaccaagta agctactgct
    67321 ggtgttgcaa ggacaccaag tttgtatacg tgaatcccta ctgaaaggag acctgccacc
    67381 aaggccgatt ccagcatttc ccctgaaata cgtgtgtcac gtcctacaaa gactttcggc
    67441 gcttccgttt catgttgact aagaacatag cctccaaaac gtcctagttt aaaggctaat
    67501 tctggtgtta gctctaggtt agcttctcca cggactccat cagtcccaaa atatttaccc
    67561 attgttataa aatccttttc tatttttaat tcgtttttga actagttgct ttcgttgacg
    67621 aagatgtctc cgatgaactg cttgtacttg aatttgatgt gcttgaactt ggtgctactg
    67681 gttttgtagt caccttcatt attgtatcaa acggagtgat aactgccggt aagacaacac
    67741 cattgcggtc gattgcctgc aaaggtactg aaccactgta attacctgtt atgcgttcgc
    67801 tagttggcaa gacagcgata atcttatcaa ttctatccaa tgtctcttgg tcactcgtaa
    67861 tcgacacttc tttatctgac accatgacat tttcaatttg tacccgacta tcaatttgac
    67921 tagggtcaat ctctggtaca atctttacct tatccttctg agccttctta ccaatcttga
    67981 ctgtaatttt ttgcggagtc gccacagcgg tcagcccatt gggtaaatct tcaatgctca
    68041 aaggaacttc aatcgttcca acaccggcat ctgttaggtc agcagtaacc ttgaatttac
    68101 gtgtactttc ttgcatttca ctagctagcg ataggcgatt tgcaccagtc aagaccactg
    68161 atacttctga agcaaaaccg ctaataaaat acttatcact attatagcgt atgtcaatag
    68221 ggacatttgt tactgtatta gtataggttt ccgtttttac ctgcctagca ctggtactgt
    68281 tttgaaaatt cgtcgccgta gcatagacaa ataagacaca agcaaaaaag agtgaggata
    68341 tgatatataa actatttttt ttcatgtttc catcctccta gcaatcgttc tttaaaacta
    68401 agacccactt cctcttttgg aagtaagatt tcacgtaatt ctgtttcaaa ttcatcaagt
    68461 gttaggttgt gcttaaacct tccattatag gttatcgaaa ttcctcccgt ttcctctgat
    68521 acgacaaaag tcaaggcatc tgagacttct gataaaccga tagccgcccg gtgtctggtc
    68581 ccaaattcct tggaaatccc tgtgtttttt gtcaagggca gataggcaga cgtcacagcg
    68641 atacgttctt ctttgataat caccgcacca tcatgtaggg gagtgttggg aataaaaatg
    68701 ttaatgagaa gttctgcaga aatcttagca tccaagggaa ttcctgtcga aatatactcc
    68761 tgcaaggtac gtacacgctg aatagcaacc aaggccccga ttttacgagg actcatgtat
    68821 tcaacagact taacaaaggc acgaatcatc tgttcctcag cactaatagg ggcattggaa
    68881 aagaaatctg tcgctcttcc caaacgttcc aaaccagtcc gaatctctgg agagaagata
    68941 acaaccgccg caataacccc ataagtaata atttgattga ttaaccaaga aatcgtagtc
    69001 aaaccaatca tatttgcaag gatttgagct aaaataaaca ccaaaactcc acgtaccaaa
    69061 atcataatct tggttcctgc aatagctttt gtaaaatggt ataaaatata agcaacaatc
    69121 aaaatatcaa tcagattgat agctatcgtc catggacttg caaacaaact ggtccaatat
    69181 tgcagattgg ataattgttg aaaattcatc cccgatatcc tccctatcaa aacactttcg
    69241 tcctattata ccattttctg gcattttttt ccctatccta gtccatttta cattgaacaa
    69301 aaatatgata aaataaactg actagaaaaa acaaaggaga aactatgtct caactctatg
    69361 atattaccat tgtgggtggt ggtcctgtcg ggctttttgc agccttttat gcccacctac
    69421 gccaagccaa ggttcaaatc atcgactctc ttccccagct aggtggacaa cctgctattc
    69481 tctaccctga aaaggaaatc ctagacgtac caggcttccc aaacctgact ggagaagagt
    69541 tgactaaccg cttgattgaa cagctaaatg gatttgatac ccctattcat ctcaatgaaa
    69601 cggttcttga gattgacaaa caagaagaag aatttgccat cacaacttcc aaaggaagtc
    69661 acctgactaa aacagttatc atcgctatgg gtggcggtgc cttcaaacca cgtccgctgg
    69721 aacttgaagg ggttgaggac tatgaaaata tccactacca cgtttctaac attcagcaat
    69781 acgctggtaa gaaagtgacg attcttggtg ggggagactc ggctgtggat tgggctttgg
    69841 cttttgaaaa aatcgcacca actacccttg ttcaccgcag agataatttc cgtgccttgg
    69901 aacacagtgt tcaagccttg caagaatcat ctgtaaccat caagacacca ttcgccccta
    69961 gccaactcct tggagatgga aaaacgcttg ataaacttga aatcacaaaa gtcaaatctg
    70021 atgaaactga aaccattgac ctagaccacc tctttgtcaa ctatggtttc aaatcttctg
    70081 tcggtaacct taaaaactgg gggctcgacc tcaaccgtca caagattatc gtcaacagca
    70141 aacaagaatc cagccaagca ggtatctatg ctatcggtga ctgctgctac tatgacggaa
    70201 aaattgatct gattgcgaca ggtctagggg aagctccaac tgctgtcaac aacgctatca
    70261 actacattga ccctgaacaa aaagtacaac caaaacactc taccagttta taaaaaagaa
    70321 ccacgagtca cataggattc gtggttttat aattcatccg ctatcttatt gatttttctg
    70381 agtctgtgat tgacaccact tttggtcaga ggggtgctga gactatctgc taactgctgg
    70441 atagagtagt ctgggtgctg aatcctcagt tgcgccactt cctgcaaatc tactggcaaa
    70501 ttttctaagc ccatgatatc tttgatttta ctgatattgt taatggtctt catgctggca
    70561 gaaactgtcc gagcgatatt agctgtctcg gcattattag ctcgattgag gtcgttacgg
    70621 gtttctcgca aaatcttaac ccgctcaaaa tcatcacgtg cctgcatggc tcctattact
    70681 atcaagaagt ccataatgtc ttctgctcgc tggagatagg tcacagcccc cttcttgcgc
    70741 tcaagcacct tggcatccag taaaaactgt tggagaaggg aggcaattcc ttgcgcgtgg
    70801 tccagataaa cagaactgat ttccaactgg tacttgcctg actcagggtc acgaatgctc
    70861 ccatttgcca agaaagcgcc acagagatag gcacgacctg cttcctcatc cgataaaatc
    70921 gcctcatcaa tacctgtttc caggccaaag aaagagtctg ccaagtgcaa atcacttaac
    70981 aaatcctgca ccttttcatc tgtaaaaacg gtatagacgc gattcttgcg aagattgctc
    71041 cgttggtggt gacgaatttc agatttgatt tcatagaaat ggagaaagga ctcatagagg
    71101 tgacgggcca gtttggcatt ttctgtcaca actgacaaag tcaagcccga agtcgagaga
    71161 ccgatgctac cagacatttt gataatggca gataattcat gccagctcag atggtgttgg
    71221 cccaggattt cttcttttac tgctactgtg aaactcattt tttcacctgt ataatgcgca
    71281 tcaactcgtc cacaatcaaa tctccatcgt ggaaggcacc gccattttcc agacgaagga
    71341 agttagatga aatcacgcgc gaaacttgct tacaaagacc tacaaaatcg tgttccactt
    71401 gcaccaagta ttcatcaaaa cggttggaat tcatgtattc ctgaggcact ttttcaatat
    71461 tcaccaagac agtgtcgata aaaggacgac caaggtgacg atgcaagact tccacgtggt
    71521 tgctatctgt aaagtgttcc gtctccccac gttgggtcat gatattgcag acataggcaa
    71581 tttctgcctt ggtttccaaa agagcccgcc caatttcctt aatcacgata ttgggcaaaa
    71641 tagaggtaaa gagggaacct ggccctagga caatcatgtc actttcaagg atggtctgca
    71701 ctactcgacg gctggccaga ggcgtatcat cgtttagggc attggtcaca tagacattgt
    71761 caattatgcc tcgatggtct acaatatgac tctctccagc cacttctgtc ccatcctgaa
    71821 agactgcatg aagggtcaaa ggatggtcac tggaaggata aattttccct gttgtatgga
    71881 aaaatttgct caataactgc atggcattat aggttgaacc ctgcatttct gacaagccag
    71941 caatgatgag atttcccaat ggatggccag caaaggctcc ggcatcctca gagaaccgat
    72001 actgaaagac cttctcataa aacttaggca tatccgacat ggccacaagg acattacgaa
    72061 gatcacctgg cggtgtcaac tgttgcatat tttttcggag ttcacctgaa gaaccaccat
    72121 catctgccac cgtcacgata gctgcgattt ccacatcttt ttcccgcaga ctttttagaa
    72181 tgacgggaat tccagtccct ccaccaatca ccgttatctt tggttttctc atgaacggtt
    72241 taccgtttcc tttctgcggt ctttgtcgcg atgcccttca ttaacagacc aattcttgga
    72301 taagtcctgc accaagcgtt tagcaaatgc cacactacgg tgttgtccac ccgtacatcc
    72361 catggcaatg gtcaaaacgg acttaccttc cttttggtaa cttggcagaa tcggctcaat
    72421 caaggccaat aaatgttgat aaaagtcttc tgactcagga tggttcatga cataatcata
    72481 aacaggttca tccacacccg tttggtttct cagttctggt aaataatagg gatttggcaa
    72541 gaaacggaca tcaaagacca agtccgcatc aatcgggatt ccatacttaa atccgaaaga
    72601 catgacttcg atacggaaag actgggcttg ttcttggtct gaaaactgct ctgcaagggt
    72661 tttgcgcagc tcacgtggag tgagttcagt cgtatccacc acattttggc tcatattttt
    72721 caaaggtgcc aagagttcac gttccaactt gattccatct aaaatacgac cgtctgctgc
    72781 tagtgggtga ctccgtctgg tttccttgta acgagcgacc aattccttat cagccgcatc
    72841 caaaaagagg attttgaaat ccaaaccatc ttgattttcc aactcatcca aaacagcttg
    72901 aatctctgaa aagaaagaac ggctacgcat atccactacc aaggccaact taggattgtc
    72961 ttccttaatt tcaaccagct gcaaaaactt aggcaagaga gctggcggca tattatcaat
    73021 ggtgaaataa cctagatcct cgaaggactg aatggctaca gttttccctg cgccactcat
    73081 ccctgtcaca atcaccaagt gaagttgttt ctttgtcatc tttttctcct tatatcaaaa
    73141 gaagtttggc aacaccaaac ttcaactagc ttatccaatc tctgcgatga cttcaatttc
    73201 gacttttaca tcacgaggaa gacgagctac ctccacagct gaacgagctg ggaattcctc
    73261 tttgaaggcc gtttggtaaa cctcattaaa aggaacaaag tcgttcatat cgctcaagaa
    73321 acaagttgtt ttgacaacat ggtcaaagtc tgttcctgct tctgccaaaa tagcaccgat
    73381 gtttttcaag acttgctctg tctgttcttg gatattctct cctacaattt ccccagtttc
    73441 aggggatagg ggaacttgac cgctagcaaa caaaaggttg ccaacgattt ttccttgaac
    73501 atagggtccg atagcctttg gggccttatc tgtatgaatt gtttttgcca ttttcttttc
    73561 ctcacaattt ttctaagatt gcatcccaag cctcatccat ccctgccttg ctgacagatg
    73621 aaaagaggat gaaatcgtca ctcgggtcaa agtttaattt ctttttgatt gctgattcat
    73681 gcttgttcca tttaccacga ggaatcttgt ccgccttggt cgccacaatg atgactggaa
    73741 tctcataata cttgagaaat tcgtacatct gcacatcatc tgctgacggg tcatgacgaa
    73801 ggtcaactag actgacaacc gcacggagat tttcccgagt cgttaagtac tcctcaatca
    73861 tgcaccccca cttttcacgt tcctttttag aaacacgggc atagccataa ccaggcacat
    73921 ccacaaagcg catcttgtca tcaatgttaa aaaagttcag gagctgggtt ttaccaggtt
    73981 ttcctgatgt acgggcgaga ttcttacggt tcaacatagt gttgataaag ctggatttac
    74041 caacatttga acgccctgct agggcaatct ctggcagttc atcctgcgga tagtgggact
    74101 tattagctgc actgagcaag atttcagcat tgtgtgtatt aagttccata gtcacctcta
    74161 ggctgtttct aggatcggtt tatccgttcc atcgacagtt tctttagtga tgcgaaccaa
    74221 tttcacattt tcctgactcg gcacctcaaa cataacatct agcatggttt cttcgataat
    74281 ggagcgaagt ccacgcgccc ctgtcttccg ttcgattgct ttattagcaa tctcttgaag
    74341 ggcttcgtcg tcaaattcca actcaacatc atcataagaa agcaaagttt ggtattgttt
    74401 caccaaggca tttcttggct ctttcaagat gcgaaccaag tcatcaacgg tcaattgctc
    74461 aagagccgca aaaacaggca agcgtccaat caactcaggg ataataccaa atttttgaat
    74521 gtcttcagcg atgatttctt gcatatatga gctgttttcg tcaatcgcct tattattttg
    74581 accaaatccg atgacttttt cacccagacg ttgtttgaca atttcttcaa taccatcaaa
    74641 agcaccaccc acgatgaaga ggatattttt tgtatccact tgaatcatct cttgttgtgg
    74701 atgtttgcgt ccaccttgag gcggcacgct agcaacagtt ccctcgataa tcttgagaag
    74761 ggcttgttgc accccttcac cagaaacatc acgtgtgata gacacattct cactcttctt
    74821 ggcaatcttg tcaatttcat ccacatagat aatgccacgc tctgcacgtt cgatgttaaa
    74881 gtcagcaacc tgcaagagtt tgaggaggat attttccacg tcctcaccca cataaccagc
    74941 ctccgtcaga gctgtcgcat ccgcaatagc aaaaggcaca ttcaagctct tagccaaggt
    75001 ctgggcaagg aaagttttcc ctgaaccagt tgggccaatc atcaaaatgt ttgacttctg
    75061 caaatccaca tcttctgact cttcgcgtgt atcgtggaaa ttgatgcgtt tgtagtggtt
    75121 ataaaccgcc actgccaagg cacgcttggc acgatcttga ccaattacat agtggttcaa
    75181 gatatggagg agttcaattg gttttggcac ctcagacaag tctgccaaga cttcctcaac
    75241 caattcttct cgaatgattt cctgagctaa ctccacgcat tcattacaaa taaaagcatt
    75301 gttgccagca attatttttt gtacttcttc ttggtttttg ccacaaaatg agcaataaac
    75361 catcatatca ttttttctat ttgtagacat gatttccttc cattctatac tgtcattcta
    75421 tctaaaataa ggtcatgtaa aaagcatgaa tactattgac cagattggta aaggcattta
    75481 accaaaggag gatagaaagc ccgtaacgct ttttacgaaa agcctgtgct cctgccagaa
    75541 agcagatgaa acacagaaaa gccgtgaata gaccaaataa actccgttcc attatacttc
    75601 ctttctcttg cggtattgga tggtaaaatc ataaggattc ttctcatctt tggcgtaaaa
    75661 tttgcttgaa actgtctcaa aaagagacaa gtcaagctct tcagggaaat aggtatctcc
    75721 ttccacccga gcatgaatgt gagtgacaat cacttcatca aggtaaggtt caaaagcctg
    75781 aaaaatttgc ttcccaccga taatgtagag attcttttct tgatcctgat accagtcaag
    75841 aacagactgg acgtcctgaa aagtagcaac cccatctatc ttttcttccg gattacgcgt
    75901 caaaatcagg gtttcccgtt ttggaagcaa gcgacgcccc atcccatcaa aggtcacacg
    75961 ccccatcaag atagcatgat tcagagttgt ttctttaaag tgctgcaatt ctgctggcaa
    76021 atgccaaggc agacgatttt ccttaccaat cacaccctct tcatcctggg cccaaatagc
    76081 tacgattttc ttagtcatgc ttccatcctt ttcactgata gtactatttt atcaaaaaac
    76141 tcaaaaaaag actggtttgg aatagcttac aaaatagaaa aaatctgtaa gaaatttcct
    76201 acagatttat ctatgtttcc ttatttctta caaaccaggt gcttgtccaa gttcggctgc
    76261 aagcatccaa attgttttat ctgtttcagt tttagcgcct gcaaagatac cgtttgtcac
    76321 atcgtcacct tcttcatcag tgacatccaa acctttttgg aaaagttctg acaagtaacg
    76381 gtagataaca agaacacgtt ccaagctttc ttcaacatta cggtattcac cagcttcttc
    76441 ttcgatttca ctattttgaa ggaactctgt caatgtagag aatgggcttc caccgagtgt
    76501 aatcaagcgt tcgctgattt catccaattg accgtcaaga gcttccatgt actcatccat
    76561 ttttggatgc catacaagga aaccacgacc atgcatatac cagtgcactt ggtgcaaagc
    76621 aacgtgagct acatacaaat cagcaacagc ttggttcaag acttcctttg tttttgccaa
    76681 tgctactggc gctgcttttg tcaatgatgt tacgtctttt actgcttctt ttttcaattc
    76741 taccattttc tttacctcat tcattatttt ttgtaaccac ttcttaatga ttactacctt
    76801 agtatactac taaggaaaac caatagcaag acaaagaact tatatgagaa aagttgcaat
    76861 agactgataa tttaagaatt ctttagaaga caaaaagagg gttggatgct tatagtcaat
    76921 ggaaatccat cagcaaacta ggaaactaaa cccagcttga ccaaagcaca agttttgagg
    76981 tcgcaggtag aactgaccaa gctgatgtgg tttgaagaaa ttccccaata ctataataga
    77041 ttgaaataag atgaaaccaa gtcgattagg aaaggtaaat gaatttctaa aatgttttac
    77101 caatcacaag gtatttgtct atattcaatc tactatataa gcttcatttc cgagcaagat
    77161 cttgaattta ctcgaggatg aactatcata aaacaaagaa aaagagggtg ctactatcac
    77221 atccctcttt caaatcatcg cttaatacca aacgctgaca tctacgcgcc cttggattcc
    77281 tttcatgtat tcagaagagg tatattgcca acctttttct cctgaataat aagggttttc
    77341 ccattctaaa gcattcgtat aggccgctac ccagtttaca tgttttaaaa tatctgggtg
    77401 ttttaaacgc gtctgtaata aactacgata gctatagaca tacacatttt gataacccgc
    77461 ctgcttcatc gtgtccatgt acttgttgat gattttaacc caagtgtctg tatcacttgg
    77521 agctctcttg ctcttattta catattccca gttctcaaca tcataataga tagggtaaga
    77581 caggttcata ttgtatttct ttataagttc aatggtctgt ttagcgtcat tctcagcatc
    77641 ggtctcattt tcagcatagg tatagagata gacaccataa ggaattccca gacggtttaa
    77701 ctccttaatg ttatgcgcca attccttgtc ttctttaccg ctataaccta gacgaacaat
    77761 gacaccatcc acctcgttct catcaataac ctttttccaa tcattgatac gaccattgtg
    77821 ctcactaata tcaatgattt tcttagcatg ttcggttccc acttgttctt ctctattatt
    77881 aaagaaatag cgtttaccat ctctgtgaac ccagccgaca ttcaaatctt tcttttcttt
    77941 gagctcacca gaggccgcaa agatatagcg agcaccatcc ataatcactt cgtcagtcgc
    78001 catagcacca cttccagtca aatagtagtt gccttgccac tcattccgag ccatatagcc
    78061 ccacttcttg aaatagtacc atttgccgcc cactttttgc cactcttggt tagcataagt
    78121 tccatcggat tttagataaa aataagcaga ataggctgga tcatagagcc attcattttg
    78181 catcatagct ccttgaccat tcaagaaata acttccttgc cattggcttt tagccatgta
    78241 accccacttc ttgaagtagt accacttatt tccaatcaat tgccattctt gatgagcata
    78301 agccccatct gacttgagat aaaaccaact cttgtaatta ctgtcataga tccactcgtt
    78361 ttgggccata tatccacctg atttcaggta gtaatttcca tgccattcat tctgcgagta
    78421 acgaccatct gaattaatat aaaaccaagc cttatagtag ttgtcaaaaa tccattcact
    78481 ttgagcttta gaaccatcat cctttacata ataatcccca tcccagtggg cagcagcatt
    78541 agtctgtact tctgcgctcg tttgcgtttt attagaagac tgattttgct ctgaactact
    78601 tgaagctgtc gttgtatcct gcgaagtttt tgctacttca gtttcatttg cagcgacatg
    78661 actagttgcc aagcctagta aacagatact tgctaatcca atttttgttt tcaatctttg
    78721 ctctcctata aaaaatgtaa cagacatctg aatgctgttc cacctagctt ttgctactta
    78781 ctgattattt tacaaagtca agcaaagcta agaagctttc agcttcaagt gacgcaccac
    78841 ctacaagggc accgtcaacg tctgggcaag ccatgtatga agcaacattt tcaggtttaa
    78901 cagaaccacc gtattgaaca cgaactttgt ctgcgacttc ttgaccaaag tcagcagcta
    78961 caacgtcacg aacaacttta cacatttttt gtgcatcgtc ttgtgaagct gatttaccag
    79021 taccgatagc ccagattggc tcataagcga taactgaggc agcaacttgt tcagcagtca
    79081 atccagccaa tgcagcagat acttgagcac ctacgaattc agcagcttta ccagcttcgt
    79141 aagtttcaag tgattcacca caacagatga ttggaagcat accgttcgca aagattgctt
    79201 ttgctttttt gttgatatct tcgtcagttt catggaagta gtcacggcgt tctgagtgac
    79261 cgataacaac gtagtcagta ccgatttctt tcaaaacttg tgggctagtt tcaccagtga
    79321 aagcacctgc attttcaaag tagcagtttt gagcagcaac tttaaggttt gagccttttg
    79381 caacagcaag aacagttgtc aaatcaagag ctggagcagc gatacctgct tcaacaagat
    79441 ctgatgaagg aagttttgat gcaactgctt caacgaatgc tttagcttct tctggatttt
    79501 tgttcatttt ccagttacca gcgataaatg gtttacgtga catttcacat acctcttttt
    79561 tcaatttatt ttctatttat tctatcacaa ttatacacag cttgcaaatc ttactcggat
    79621 ttcaagccta cttgcatgga ttaatccttc cagagatcca tggcatttct gaaatctgca
    79681 gatacctgtg tcaactgagg attgcttgct tctctttctg ctctcttggc ctcaatttga
    79741 gccacactct tgattccttc atggcgccag tttctcaaaa tcgcctgaat gtacttccag
    79801 tttggttttc cattcaaaac agcttcacga agagcctcct taatcaagtc agcactggtt
    79861 ccatcttcct ttagtgtctt ggtcaaatcc tcaatctcaa aaggcgtcaa caatcgtccc
    79921 aactcctgct ggaaggtttc caccaaatcc ttgagctggt tttgaggtgt tagctggtct
    79981 gaacttgaat gaactgctcc aaacaggtca tccaaacgtt ccaaggccaa actagcatca
    80041 aagagcaatt caatttcgcc atttaattcg atagtacgat actggagcag tcccctttcc
    80101 gtcagattag aaatggactg gttgacatcc gaaatttcct tgccaatcct ttcagcaatc
    80161 tggcttggcg acatttcttc taagcctgtc gtattttgca aatagaaaaa ttgccaaacc
    80221 agaaaatcgt cgctagaagg aaagagttcc ttaaaatgca agagcagggc actcggtaaa
    80281 accaaggtac ctgatttaaa agcgtctaaa tatgtcataa ttcctcttat aaatacccat
    80341 atgcagatgc atcatcttct atctttctcc aatcaaaagg cgtctcctga tagaccgcat
    80401 ggtttaccca attactgaaa aagagggctg cagatgaaga ccaacaaaga caaggtacct
    80461 gattaacatc atcatcttta aagtaatttt ctggaatatg tgggtcgaaa cctgcatcac
    80521 gatctcgaaa atactctttt gccaaggtat cacggtcata ctccaaatga ccaaaactat
    80581 aaatttctcg taaatcacga ctggccaaaa tagaaacccc aacctgaggt ccttctgata
    80641 aaatctcgag attggtcttg tttaagacct cttccttaga aatctccgtg tgccgtgaat
    80701 gaggggatac atagctatca tcaaagcctc taaatagaag gtgaccctct tttagggtgt
    80761 cctgaggata aatacctgat agcttactgt ccatctggta tttttctaca ccatagcgca
    80821 gataaagccc agcctgagcc ccccaacaga tatgaagggt cgaatagaca tgagtcttag
    80881 accactcaag catctgtcta aattcctccc aatagtccac ttcctcaaat ggtaaatgct
    80941 caactggagc acccgtgatg atcatcccat caaaatactc atccttgact tcaggaaaag
    81001 ttttatagaa ggtctccatg tgctctgaac gagttgtttt agaacggtgg ctctccatat
    81061 agagaaaatc aatatccagt tgtaggggtg tattagccaa gtggcgcaac aactgggtct
    81121 ctgtgaccat tttctgtggc atgagattta aaattaaaat cttcaaagga cggatatctt
    81181 ggtgggcagc acgttgatca tccatgacaa agatattctc tgtccgtaaa atctcaacag
    81241 ctggcaattt tttatcaatt cgaatcggca taaccctctc ctaactgtac tctttcagga
    81301 ataattgcat atgtttgaag acaaatctca aacacttagt ccttttatta tactgcaaga
    81361 agatatagtt ttcaattata gtttttctct aactagttat agtctatttt tatatcctag
    81421 tgtagagaaa acagccctag ggactgtttt cattaataat gcataagaac tttgtagtcg
    81481 tagtcaccaa ttttttcacg gccgttcaat tcatccaatt caacaaggaa ggcacaacct
    81541 gccataacac caccaagttt ttcaatcatc tcgatagttg ccttaacagt tccacctgtc
    81601 gccaaaaggt catctacaat aagaacacgt tgacctggct taatggcatc cgcgtgcata
    81661 gtcaaggtat cgacaccgta ctctttttca tagtcagcag aaataacttc gcgtggcaat
    81721 ttacctggct tacgaacagg cgcaaaacca attcccaact caaaggcaac tggacaaccc
    81781 acgataaatc cacgagcttc aggtcccacg atcatgtcga ctttcttgtc agtagcatac
    81841 tgaacgattt cacgaacagc gtagctataa gcatttccat cagccatcaa aggactaata
    81901 tcacggaagg taatgccttc ctttggataa ttttcaattg ttgcaatgta atcttttaaa
    81961 ttcatctttt ttctttcttt caaagttttt tactctctat tatagcatat tttttaagaa
    82021 agaaaaaagg aaaagttaac ttcaataatt atctaacgtt ttgacgattt ataactagcc
    82081 atcgcaataa agcccaattt ctgtttattc ttagcaaaca ttttatacat agttaaaaac
    82141 tgctttctat tctccttttt acaagcattt acacaaattt tcaaagttcc tagcaaacct
    82201 tcgtcataaa tcatacccga taatttcatt aatgtcattt caccagtcaa tgctttcaca
    82261 tcacaataac ctgattctat catcacctgt tcccaaccat cttgagttaa aggacctaca
    82321 tttacatgaa ttgcttgtga taattcctgt ctgatagact ctttagcttc cttaagaagc
    82381 acatcatgtg tcaagagaag acctccaggt tttaataccc ttagatattc cattacacat
    82441 tttttcttag cttgatcggc ttgcatagtc agcatagctt catttataac aatatcaaaa
    82501 ctagcatctt gataaggaag tttcattgca tttgctcttt caaaactgat taaatgagca
    82561 acacctgccg ttccagcaga ttttttagcc acttctaaag cttgagcatc catatcaaca
    82621 gcagttatct tgcaaccaaa acgctgtgcc aactcaattg ctgtagttcc cctattacac
    82681 gcaacctcta gtattctctt ttcttttgaa aatcctcctt ctgcaattaa ccaatctgtg
    82741 gcacgctttc cacctggacg taagcgtttt ttccccaatt ttgctaaaaa cttatgacct
    82801 gcttctgaca tttgaacacc tctgtttttt cttcattata acacaaaatg atattatctg
    82861 acaattctaa tctattattt gataaactag aatcaaaagc atacaagtca ccataactat
    82921 agcataaatt tattattacc tctctagttc gaattcaatt gctcacgtag tttacgcata
    82981 tagcttcact tgtagatggt acccacaaat aatactcaat ggaaatcaaa gagcaaacta
    83041 ggaaactagc cgtaagctgc tcaaagtaca gctttgaggt tgcagataaa actgacgaag
    83101 tcagtaatca tacgtacggc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt
    83161 attaaagagc atcacaatat agatgcataa tatgacttcc ctagcaaaaa ggagagaagc
    83221 attttgtttc tctccctaga tcaactgata tctctccact acaattgata aagagatatc
    83281 ttttcttgta gtgctttgaa ttttatttat tttagtagat tgttttttca gtttctacat
    83341 cgaagaagtg tgctttgttc aagtcaaatc caagctcaac tgttgcacct gtttgcaagt
    83401 agtcacgagc atcaactttt gcaacaaact cgtctttacc aacttggcag taaaggtgag
    83461 attctgaacc aagcagttct gatacagaga tagtcgcttt tacaacacag tctgggaatg
    83521 tttcaaggaa agcaggttct gcattcacgt cttctggacg gataccaaag atcaattctt
    83581 ttccttcgta gcctttttca cgaagaactt tcaatgctcc ttctggcact ttcaaacgga
    83641 aaccgtcaga aacaatttcg ctaccaacca atttcacgtt gatgaagttc atagctgggc
    83701 ttccgatgaa tcctgcaacg aatttgttaa ctggattttt gtaaacttct tgaggagtac
    83761 cgatttgttc tacacgtccg atagtacctg taccagcagg gttcttagta gctgacataa
    83821 taacgatacg gtctgcaagt gtcatcgctt ctgtttggtc gtgagttaca tagatagttg
    83881 tagctccgat acgacggtga attttagcga tttcagcacg cattgataca cgaagtttgg
    83941 catccaagtt tgacaaaggt tcgtccatca agaatacttt cgcatcacgg acaatcgcac
    84001 gccccatggc aacacgttga cgttgaccac ctgaaaggtc agctggttta cgttccaaga
    84061 attctttcaa tccaagtatt tcagctgctt cttgaacacg tttgttaatg tcttctttgc
    84121 tgtatttacg caatttcaaa ccgaaagcca tgttgtcata aacagtcatg tgtgggtaaa
    84181 gagcgtagtt ttggaatacc atggcgatat cacggtcttt tggagctacg tcgttgacaa
    84241 ccacgccatc gatagatgca gtaccttctg taatgtcttc aagaccagca atcatacgga
    84301 gtgtagttga tttaccacat cctgaaggtc ctacgaaaac gataaattct ttatctttga
    84361 tgttcaagtt gaaatcttca actgaatagt gttcgctgtt tggatatttt ttgtaaatat
    84421 ttttaagatt caattctacc atgaggtgaa ctccttttgt cttttgataa ttatattata
    84481 gatgaaaacg ctttatattt ctatggcaag atgaccaaaa aaataaaaaa gttctgtgca
    84541 acttgcacaa aactttagag aatatcggag aatttgaaga agataatctt tattattctt
    84601 ctatgacaaa agcagaaaca aggatcagtt ttcccatatt ttcgctgatt ctccactaca
    84661 tttgactgga ttctaatttt ttagagaaat acaaaagagc tagctttagc taactctttt
    84721 cctatgcgga gagagggact tgaaccctca cgacctaaag cggtcacagg atccttagtc
    84781 ctgcgcgtct gccaattccg ccatccccgc gtcgattact ttactagtat atcaactttt
    84841 gggatgcttg tcaacacttt ttttcaaatt ttttcatttt caccaaccag gttactcaga
    84901 aagttcattt agattttcat ctactaactt agctccgagt gtatttttga aatgacctag
    84961 ggcaaattga tgattttcag gccagatgga agcaacagct ggtttaacaa tctcgatgtc
    85021 atatcctaga ttataggcat ctatagctgt atgtaggaca cagatatccg tcaagacacc
    85081 tgttaagata acggtagaca ctctacgctc tctcaaacga atatctaggt cagtccctga
    85141 aaaagctgag taatggcgtt tatccatcca aaagacacga ctgtctgaac catgctcttg
    85201 ataaaagatc cccaaatctc catataaatt ccgtccactc gtcccaatca gattatgagg
    85261 aggaaataac ttactttccg gatggaaaca atcgttttct tcatgagcat caatagtaaa
    85321 gaagatataa tctcctcgtt caaaagctaa tcgagttacc ttgctgatgg catccgaaat
    85381 cgcctgagct ggagcacctg ctgtcagctt cccactatca gcaacaaaat cttctgtata
    85441 atcaatcgaa attaaagcct ttgtcattag taatctcttt tcttcacttc ttcaaaaata
    85501 tctgaaatca agaccttaag ataggttccc ttcattccaa gtgagcgact ttcaataatc
    85561 cccgcagact caagtttacg aagagcattg acaatcacag agcgagtgat tccgatacga
    85621 tctgcaatca ctgacgcagt caacttccct tcatttccat ttaattcccc taaaattgct
    85681 gaaacagcac ggagttcgga gtaagaaagg gtattgaccg ccatggtgac agcagtacga
    85741 cgacgaatat ttttctcatc ttcttcacgt tggaagttaa gaagctgaat cccaacaacg
    85801 gtactggcaa tctcaacaag aaccaagtcc tcatcttcga attttttatc attacgccaa
    85861 ataatcaaag aaccaaggcg aatccccgat acatgaatcg gtgcaatagt cgtcaagcca
    85921 tctggaaaat catctctact ctcaacaggg aaaatactca tatcatgctc aacaggcaag
    85981 tttgcttctg tttcgtaaat catattagcc ccttgaacgt agtcatctgg gaaaatctta
    86041 gtttggaaga attgctctac gcgatctgta tttgttttat aacgcataaa atagccaagc
    86101 agacgtccct tactattgat aatgcaggca ttgcaatgaa taatatccgc taactgacgc
    86161 gtaatagcgt tgtaagggag ctcatcctgc aactgctcct ctgagcgttt caaaattgat
    86221 gtaatttttc tagttttttc taataaatgt gccatttttc acctcgaatt taatcgctat
    86281 cattataaca taaaaacgtc tctttttcaa taattatctg aaaattcctt attgacttgc
    86341 attgacttac aatttaatta
//
LOCUS       DAVLTT010000002        75076 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLTT010000002 DAVLTT010000000
VERSION     DAVLTT010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 75076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75076
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.002"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            2..74
                     /locus_tag="VYN15_000085"
     tRNA            2..74
                     /locus_tag="VYN15_000085"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            99..171
                     /locus_tag="VYN15_000086"
     tRNA            99..171
                     /locus_tag="VYN15_000086"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:132..134,aa:Lys,seq:ttt)
     gene            177..258
                     /locus_tag="VYN15_000087"
     tRNA            177..258
                     /locus_tag="VYN15_000087"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:211..213,aa:Leu,seq:tag)
     gene            277..349
                     /locus_tag="VYN15_000088"
     tRNA            277..349
                     /locus_tag="VYN15_000088"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Thr,seq:tgt)
     gene            372..443
                     /locus_tag="VYN15_000089"
     tRNA            372..443
                     /locus_tag="VYN15_000089"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:404..406,aa:Gly,seq:gcc)
     gene            451..536
                     /locus_tag="VYN15_000090"
     tRNA            451..536
                     /locus_tag="VYN15_000090"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:485..487,aa:Leu,seq:taa)
     gene            546..619
                     /locus_tag="VYN15_000091"
     tRNA            546..619
                     /locus_tag="VYN15_000091"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Arg,seq:acg)
     gene            635..708
                     /locus_tag="VYN15_000092"
     tRNA            635..708
                     /locus_tag="VYN15_000092"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:669..671,aa:Pro,seq:tgg)
     gene            714..787
                     /locus_tag="VYN15_000093"
     tRNA            714..787
                     /locus_tag="VYN15_000093"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:748..750,aa:Met,seq:cat)
     gene            801..874
                     /locus_tag="VYN15_000094"
     tRNA            801..874
                     /locus_tag="VYN15_000094"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:835..837,aa:Ile,seq:cat)
     gene            885..974
                     /locus_tag="VYN15_000095"
     tRNA            885..974
                     /locus_tag="VYN15_000095"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Ser,seq:tga)
     gene            985..1058
                     /locus_tag="VYN15_000096"
     tRNA            985..1058
                     /locus_tag="VYN15_000096"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1019..1021,aa:Met,seq:cat)
     gene            1062..1134
                     /locus_tag="VYN15_000097"
     tRNA            1062..1134
                     /locus_tag="VYN15_000097"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1095..1097,aa:Phe,seq:gaa)
     gene            1154..1224
                     /locus_tag="VYN15_000098"
     tRNA            1154..1224
                     /locus_tag="VYN15_000098"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1186..1188,aa:Gly,seq:tcc)
     gene            1260..1333
                     /locus_tag="VYN15_000099"
     tRNA            1260..1333
                     /locus_tag="VYN15_000099"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1294..1296,aa:Ile,seq:gat)
     gene            1340..1427
                     /locus_tag="VYN15_000100"
     tRNA            1340..1427
                     /locus_tag="VYN15_000100"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1374..1376,aa:Ser,seq:gct)
     gene            complement(1553..2488)
                     /locus_tag="VYN15_000101"
     CDS             complement(1553..2488)
                     /locus_tag="VYN15_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV1451501.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(2485..3345)
                     /locus_tag="VYN15_000102"
     CDS             complement(2485..3345)
                     /locus_tag="VYN15_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1451502.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            3453..5615
                     /locus_tag="VYN15_000103"
     CDS             3453..5615
                     /locus_tag="VYN15_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV1451503.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            5707..6966
                     /locus_tag="VYN15_000104"
     CDS             5707..6966
                     /locus_tag="VYN15_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1451504.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKEGMVNDLNAFFNPMKADVD"
     gene            6980..7846
                     /locus_tag="VYN15_000105"
     CDS             6980..7846
                     /locus_tag="VYN15_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1451505.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIIAIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFFQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7860..8693
                     /locus_tag="VYN15_000106"
     CDS             7860..8693
                     /locus_tag="VYN15_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1451506.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            8694..8774
                     /locus_tag="VYN15_000107"
                     /pseudo
     CDS             8694..8774
                     /locus_tag="VYN15_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            9051..10493
                     /gene="gtfA"
                     /locus_tag="VYN15_000108"
     CDS             9051..10493
                     /gene="gtfA"
                     /locus_tag="VYN15_000108"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV1451507.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYENLEEYFGDDIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKGLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQIYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            10631..11824
                     /locus_tag="VYN15_000109"
     CDS             10631..11824
                     /locus_tag="VYN15_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV1451508.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMNSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAMHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            12509..14488
                     /locus_tag="VYN15_000110"
     CDS             12509..14488
                     /locus_tag="VYN15_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1451509.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            14555..16051
                     /locus_tag="VYN15_000111"
     CDS             14555..16051
                     /locus_tag="VYN15_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1451510.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPAAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            16051..16977
                     /locus_tag="VYN15_000112"
     CDS             16051..16977
                     /locus_tag="VYN15_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1451511.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16986..18053
                     /locus_tag="VYN15_000113"
     CDS             16986..18053
                     /locus_tag="VYN15_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451512.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            18064..18990
                     /locus_tag="VYN15_000114"
     CDS             18064..18990
                     /locus_tag="VYN15_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451513.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            19481..19996
                     /locus_tag="VYN15_000115"
     CDS             19481..19996
                     /locus_tag="VYN15_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1451514.1"
                     /translation="MGILLTSLISLHQLKADKKRDVFRIGISQFITHQSLDATREGFV
                     DELAKQGYVEGENIEIDLQNAQGEQRNLKTISQQLAESSDVVLAIARPSAQSLANTTQ
                     TTPVIFSAVTDPVSAKLVESREHPGGNVTGTSDQSSDAISTQINLIKKVLPKAKTIGI
                     LYTQSEPNSVV"
     gene            20018..20419
                     /locus_tag="VYN15_000116"
     CDS             20018..20419
                     /locus_tag="VYN15_000116"
                     /inference="COORDINATES: protein motif:HMM:NF016292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451515.1"
                     /translation="MKEKGFTVVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISST
                     METVKQVSIKHKVPVFGGSTEMIAVGDLYNYGTNYEELGRQTARMLIRVLKGEKPENI
                     AVELPEKLELHTNQEMADALGIDISKLEGKE"
     gene            20431..21308
                     /locus_tag="VYN15_000117"
                     /pseudo
     CDS             20431..21308
                     /locus_tag="VYN15_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            21321..22124
                     /locus_tag="VYN15_000118"
     CDS             21321..22124
                     /locus_tag="VYN15_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1451516.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFIYVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQYPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(22157..22867)
                     /gene="treR"
                     /locus_tag="VYN15_000119"
     CDS             complement(22157..22867)
                     /gene="treR"
                     /locus_tag="VYN15_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV1451517.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            23052..25019
                     /gene="treP"
                     /locus_tag="VYN15_000120"
     CDS             23052..25019
                     /gene="treP"
                     /locus_tag="VYN15_000120"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV1451518.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKGLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            25197..26822
                     /gene="treC"
                     /locus_tag="VYN15_000121"
     CDS             25197..26822
                     /gene="treC"
                     /locus_tag="VYN15_000121"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV1451519.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTGNGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRSLNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            27078..27326
                     /locus_tag="VYN15_000122"
     CDS             27078..27326
                     /locus_tag="VYN15_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV1451520.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            27533..28327
                     /gene="racE"
                     /locus_tag="VYN15_000123"
     CDS             27533..28327
                     /gene="racE"
                     /locus_tag="VYN15_000123"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV1451521.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            28324..29295
                     /locus_tag="VYN15_000124"
     CDS             28324..29295
                     /locus_tag="VYN15_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV1451522.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            29271..29792
                     /locus_tag="VYN15_000125"
     CDS             29271..29792
                     /locus_tag="VYN15_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1451523.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            29789..30250
                     /locus_tag="VYN15_000126"
     CDS             29789..30250
                     /locus_tag="VYN15_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1451524.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            30241..30981
                     /gene="xerD"
                     /locus_tag="VYN15_000127"
     CDS             30241..30981
                     /gene="xerD"
                     /locus_tag="VYN15_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV1451525.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            30981..31709
                     /locus_tag="VYN15_000128"
     CDS             30981..31709
                     /locus_tag="VYN15_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV1451526.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            31728..32297
                     /locus_tag="VYN15_000129"
     CDS             31728..32297
                     /locus_tag="VYN15_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV1451527.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            32284..33006
                     /locus_tag="VYN15_000130"
     CDS             32284..33006
                     /locus_tag="VYN15_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1451528.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLHP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            33006..33248
                     /gene="yidD"
                     /locus_tag="VYN15_000131"
     CDS             33006..33248
                     /gene="yidD"
                     /locus_tag="VYN15_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV1451529.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(33473..34438)
                     /locus_tag="VYN15_000132"
     CDS             complement(33473..34438)
                     /locus_tag="VYN15_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1451530.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGVADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(34534..35286)
                     /locus_tag="VYN15_000133"
     CDS             complement(34534..35286)
                     /locus_tag="VYN15_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1451531.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(35283..36239)
                     /locus_tag="VYN15_000134"
     CDS             complement(35283..36239)
                     /locus_tag="VYN15_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV1451532.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILIGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            complement(36229..37188)
                     /locus_tag="VYN15_000135"
     CDS             complement(36229..37188)
                     /locus_tag="VYN15_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1451533.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKCYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(37611..38312)
                     /locus_tag="VYN15_000136"
     CDS             complement(37611..38312)
                     /locus_tag="VYN15_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEV1451534.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRATVD
                     NRASFKELDVYDASALKAYLEENQIDAVLHYAGEIVVSESIENPSKYFTANVAGRNQV
                     LKVLSEVGTQKIMFSSTASLYGNNCIDKPATEDTLIDPVNPYTETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            38713..39777
                     /gene="pepA"
                     /locus_tag="VYN15_000137"
     CDS             38713..39777
                     /gene="pepA"
                     /locus_tag="VYN15_000137"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV1451535.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQSLVKKLDRSTVDLIKHY"
     gene            39799..40095
                     /locus_tag="VYN15_000138"
     CDS             39799..40095
                     /locus_tag="VYN15_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1451536.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            40777..41220
                     /locus_tag="VYN15_000139"
     CDS             40777..41220
                     /locus_tag="VYN15_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1451537.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            41224..41988
                     /locus_tag="VYN15_000140"
     CDS             41224..41988
                     /locus_tag="VYN15_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV1451538.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFREDENG
                     CIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            42003..42731
                     /locus_tag="VYN15_000141"
     CDS             42003..42731
                     /locus_tag="VYN15_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451539.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            42724..44244
                     /locus_tag="VYN15_000142"
     CDS             42724..44244
                     /locus_tag="VYN15_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV1451540.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            44589..45395
                     /locus_tag="VYN15_000143"
     CDS             44589..45395
                     /locus_tag="VYN15_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV1451541.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(45561..46097)
                     /locus_tag="VYN15_000144"
     CDS             complement(45561..46097)
                     /locus_tag="VYN15_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1451542.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLQRELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            46230..47120
                     /locus_tag="VYN15_000145"
     CDS             46230..47120
                     /locus_tag="VYN15_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV1451543.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            47364..47717
                     /locus_tag="VYN15_000146"
     CDS             47364..47717
                     /locus_tag="VYN15_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1451544.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            47718..48755
                     /locus_tag="VYN15_000147"
     CDS             47718..48755
                     /locus_tag="VYN15_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1451545.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKVVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(48801..49808)
                     /gene="galR"
                     /locus_tag="VYN15_000148"
     CDS             complement(48801..49808)
                     /gene="galR"
                     /locus_tag="VYN15_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV1451546.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            49972..51150
                     /locus_tag="VYN15_000149"
     CDS             49972..51150
                     /locus_tag="VYN15_000149"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV1451547.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKREDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALYIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            51169..52650
                     /locus_tag="VYN15_000150"
     CDS             51169..52650
                     /locus_tag="VYN15_000150"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1451548.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGETVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEHVGISLD"
     gene            52720..53124
                     /locus_tag="VYN15_000151"
     CDS             52720..53124
                     /locus_tag="VYN15_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV1451549.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            53305..54069
                     /locus_tag="VYN15_000152"
                     /pseudo
     CDS             53305..54069
                     /locus_tag="VYN15_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
     gene            54066..54527
                     /locus_tag="VYN15_000153"
     CDS             54066..54527
                     /locus_tag="VYN15_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HEV1451550.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDASIYE"
     gene            complement(54578..55840)
                     /locus_tag="VYN15_000154"
     CDS             complement(54578..55840)
                     /locus_tag="VYN15_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV1451551.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSSAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSKGIVVASLLAIVLNAVLNHKKK"
     gene            complement(55840..56421)
                     /locus_tag="VYN15_000155"
     CDS             complement(55840..56421)
                     /locus_tag="VYN15_000155"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV1451552.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(56822..56917)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(57301..57429)
                     /locus_tag="VYN15_000156"
     CDS             complement(57301..57429)
                     /locus_tag="VYN15_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEV1451553.1"
                     /translation="MKANYPIYRPLTKRKFRVSDHYIYPHEFAVLDPNGYFLRFSE"
     gene            complement(57540..57683)
                     /locus_tag="VYN15_000157"
     CDS             complement(57540..57683)
                     /locus_tag="VYN15_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1451554.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(57695..58522)
                     /gene="xth"
                     /locus_tag="VYN15_000158"
     CDS             complement(57695..58522)
                     /gene="xth"
                     /locus_tag="VYN15_000158"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV1451555.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            58656..59111
                     /locus_tag="VYN15_000159"
                     /pseudo
     CDS             58656..59111
                     /locus_tag="VYN15_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            59264..59638
                     /locus_tag="VYN15_000160"
     CDS             59264..59638
                     /locus_tag="VYN15_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV1451556.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKP
                     GVLYSSKISSNRVNVALPYVGY"
     gene            59766..61511
                     /locus_tag="VYN15_000161"
     CDS             59766..61511
                     /locus_tag="VYN15_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451557.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            61501..63252
                     /locus_tag="VYN15_000162"
     CDS             61501..63252
                     /locus_tag="VYN15_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451558.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            63425..64117
                     /locus_tag="VYN15_000163"
     CDS             63425..64117
                     /locus_tag="VYN15_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1451559.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            64160..65386
                     /locus_tag="VYN15_000164"
     CDS             64160..65386
                     /locus_tag="VYN15_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV1451560.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            66550..68676
                     /gene="pfbA"
                     /locus_tag="VYN15_000165"
     CDS             66550..68676
                     /gene="pfbA"
                     /locus_tag="VYN15_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV1451561.1"
                     /translation="MKYFVPNEVFSIRKLKVGTCSVLLAISILGSQGILSDEVVTSSS
                     PMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNSISSNGTIRSNS
                     QLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAVGDGIHDDRQAI
                     QDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILNGINIKNHPSIV
                     FMTGLFTDDGAQIEWGPTEDISYSGGTIDMNGVLNEEGTKAKNLPLINSSGAFAIGNS
                     NSVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQIISKESIQIEP
                     LTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTLSTQNPSNIKIL
                     NNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVNAYSYKNTKDLL
                     DLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVINNNSKETEQPNI
                     ELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYISFIKSNANGKE
                     PVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVIDSNQKNGEFNS
                     SKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVKQKLPKTGSNKI
                     MELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            68660..68956
                     /locus_tag="VYN15_000166"
     CDS             68660..68956
                     /locus_tag="VYN15_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451562.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            69198..69506
                     /locus_tag="VYN15_000167"
                     /pseudo
     CDS             69198..69506
                     /locus_tag="VYN15_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            69670..70329
                     /locus_tag="VYN15_000168"
     CDS             69670..70329
                     /locus_tag="VYN15_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV1451563.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIYMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            70354..71421
                     /locus_tag="VYN15_000169"
     CDS             70354..71421
                     /locus_tag="VYN15_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1451564.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            71524..72534
                     /locus_tag="VYN15_000170"
     CDS             71524..72534
                     /locus_tag="VYN15_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451565.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFIIPSDVL
                     QF"
     gene            72546..74237
                     /locus_tag="VYN15_000171"
     CDS             72546..74237
                     /locus_tag="VYN15_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1451566.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            74240..74950
                     /locus_tag="VYN15_000172"
     CDS             74240..74950
                     /locus_tag="VYN15_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV1451567.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT        22191 a        13574 c        16680 g        22631 t
ORIGIN      
        1 aggtcccgta gtgtagcggt tatcacgtcg ccctgtcacg gcgaagatcg cgggttcgat
       61 tcccgtcggg accgtttaag ataacgcaag ttattttaga ctcgttagct cagttggtag
      121 agcaattgac ttttaatcaa tgggtcactg gttcgagccc agtacgggtc atatatgcgg
      181 gtttggcgga attggcagac gcaccagatt taggatctgg cgcttaacgg cgtgggggtt
      241 caagtccctt aacccgcatt aagatataac aaatgagccg gcttagctca gttggtagag
      301 catctgattt gtaatcagag ggtcgcgtgt tcaagtcatg tagccggcat ttttagatag
      361 aagaaaacag tgcgaacgta gttcagtggt agaacaccac cttgccaagg tgggggtcgc
      421 gggttcgaat cccgtcgttc gcttagagag gccggggtgg cggaactggc agacgcacag
      481 gacttaaaat cctgcgattg gtaacgatcg taccggttcg attccggtcc tcggcataat
      541 atggagcacc cttagctcaa ctggatagag tacctgacta cgaatcaggc ggttagaggt
      601 tcgactcctc tagggtgcat ttttctattt aactcgggaa gtagctcagc ttggtagagt
      661 acttggtttg ggaccaaggt gtcgcaggtt cgaatcctgt cttcccgatt catggcggtg
      721 tagctcagct ggctagagcg tccggttcat acccgggagg tcgggggttc gatccccttc
      781 gccgctataa tgatcttgtc ggacctttag ctcagctggt tagagctctc ggctcataac
      841 cgagtggtcg taggttcaag tcctacaagg tccatttgaa tattggagga ttacccaagt
      901 ccggctgaag ggaacggtct tgaaaaccgt caggcgtgta aaagcgtgcg tgggttcgaa
      961 tcccacatcc tccttttata ttaacgcggg atggagcagc tcggtagctc gtcgggctca
     1021 taacccgaag gtcgtaggtt caaatcctgc tcccgcaata aggctcggta gctcagttgg
     1081 tagagcaatg gattgaagct ccatgtgtcg gcggttcgat tccgtctcgc gccattttat
     1141 tgatagtatt tatgcgggtg tagtttagtg gtaaaactac agccttccaa gctgttgtcg
     1201 cgagttcgat tctcgtcacc cgctttgaac tttgttcaaa ttaccaagtt ttttaacttg
     1261 ggcgcgtagc tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt
     1321 ccactcgtgc ccattaattg gagaattact caagaggctg aagaggacgg tttgctaaat
     1381 cgttaggtcg ggtaactggc gcaagggttc gaatccctta ttctccgttt taatgagagt
     1441 ttgtaactct cttttttatt tttagagcca ataaaacttc agatccgtaa aacttaattg
     1501 aattactaat ctgaagttat ttttatatcg tttatattat aattgtgtta ttttacttcc
     1561 aactattgag agaaatttcg ccactattta gccagatttc ttttccgtta tcacattgaa
     1621 ctaaaagttt tccattttct gagatgtctt tagcaagtcc cttgtagtct ttttgctcta
     1681 gtgtgaaagt gacttctttt cctagaatga atgactgttt tttgtatagg tataatagct
     1741 cttctgctgg tgtttcgaag aaagcacgcc agatttctat gatcaattca ttccttgtta
     1801 taggagctgt agctttaaat aagctggcag ctttttcttt taattcctga gggaagtctt
     1861 taatagtgaa attgatacct actccaataa tgatatctgt gactaagcca gtttctacag
     1921 aggtcattgc ttcagtaagg attcctccaa ttttatgatt gtttagatag atatcattga
     1981 cccattttat gtcgacatct attaaagtta ggttcttaat ggctttgtag acagctccag
     2041 ctacaagtag tgtgtaggat ggtaatttgt cataggggag atttggttta agatggagtg
     2101 tcatataaat accaccttgt ggtgagtaga aggaacgttg aaaacggcct cggcctgctg
     2161 tttgatagga agctagatag agggtatttg cttcatggcc taaatcaatt gcttcttttg
     2221 catctagttg tgttgatttt gtttcgggtt taaagctgac tttaattgga agattttctt
     2281 ctagaatctc tggaagaata aggtcaccat tcatcagttt atatcctcta tttttgatac
     2341 tatcaatttc aatgccttct tgttctagtc gcttgatggc tttccaaatt gctgttcggc
     2401 ttagggatag tttttctgcg attttttctc cgctgatata gtcggtttct ttagatagga
     2461 tttggtagac agcttggtag gatttcataa tgttgccttt cttactagtt ggtattgaga
     2521 gtattctttt cttgtatgac ttggagtctg attaaagtat tgtttataag ctttcgaaaa
     2581 atggagtgga tctgaaaaac ctaccgagta tgcaattacc ttgatggact cttgggtatt
     2641 ttcgagaagt tgtctagctc ggtgcattcg aacgtagagt aggtattctt tgggtgataa
     2701 ggtattaaat tctttgaata cgcttgataa gtagcttctg tgaacggata gttcttttgc
     2761 taaatcttga attgtaagtg attgaggata gtggctatca attaatcgtt tgcattcaag
     2821 atagagttgg tgggttgatg aaatattctt ttttttctga ttgggagcaa tagttcccag
     2881 atgaaacatc agttcatgaa gttgtcccat gatatggagt tgagctaatt cacttgattt
     2941 tgtaatctga gcgaagcgga caatgtctga gatgagtttt gcagtagtct gggtatgaca
     3001 agtttcagat tggatgagat aggattgatc agaaatttgg gaaagagcaa aataatcagg
     3061 ggctttccct ccagtgattc ctaaccagta gtaggcccaa ggttctttac tatctgcttg
     3121 ataaaaggtt agttcctctg gttttaatag aaagaaatct ccttctttta aatcaacaat
     3181 tttacccttg taatgaaatt ttccttgtcc tttagtaatg taatgtagaa cgtatgtatc
     3241 acgaatggct ggaccaaaag agtaattagg tgtgcattcc tcatatccat aaaagcttag
     3301 ggcaaggtcg attgttccag tctggtattc tgaaaaaact aacatgtgct acctcctacc
     3361 taacatttta ccatattctt gagacatttt tctattttgg aaagcgattt caggtgataa
     3421 aatataatca ataaagtgat gaggtgaagt aaatgggagt taggatagag aataatctat
     3481 tttatgttga gagtaaaaat ctaagtttga ttattgaaaa tcgaaatggc tacttacttt
     3541 tgaaacattt aggaaagact attaagaact ataaaggttc caatagtgtt tatgaacgag
     3601 accatgcctt ttcaggaaat ccaacggcta ctaatcgaac ctttagttta gatactcagc
     3661 gacagatttt tggacaacat ggcttaggag attttaggaa accaactata caggttcagc
     3721 atagtgtaac tgaagtaaca gactttcgat ttgtagaagc aaagatttta aaaggtcaga
     3781 atggtccaca gggcttacct tctccacata gcatggacga tacagagact cttgtcttaa
     3841 tgttagaaga ttctaaggct caacttagtc tgactttgta ttatactact tttaataatg
     3901 atgcgactat tgctagctac agtaaattag ataataatag taatcaggaa gttgtcatcc
     3961 ataaagattt ttcttttatg gctgattttc cagctgcaga ttacgaaata gtaactctgc
     4021 agggtgctta tgctcgtgaa aagactgtta gacgtcaaca ggtagaacaa ggaatctttt
     4081 cgattagttc aaaccgaggt gcttctggtc atgctcaaac accagctctt ctactatgcg
     4141 aacaaggagt cacagaggat gctgggaatg tgtttgctat tcaactaatg tatagtggca
     4201 actttgaagc ttttgttcaa aaaaatcaat tgaatgaagt tcgggtggct attggcatta
     4261 atccagaaaa cttttcttgg aagttagccc ctgaggaata ctttgaaaca ccggtagctt
     4321 tagtgactca ttcagatcag ggattaactg gtattagtca tgaaagtcag aattttgtac
     4381 tgaagcacat tattctaagt gaattttcta aaaaagaacg tccaattcta atcaataact
     4441 gggaagctac ttactttgac tttcagagag aaaaactgtt agagttagca gatgaagcta
     4501 agaaagttgg cattgaactt tttgtattag atgatggttg gtttggcaat cgttttgatg
     4561 ataatcgtgc tttaggtgat tgggttgtta atgaggaaaa actgggtgga agtctagaaa
     4621 gtctgatttc agctatccat gaaagaggtt tgcagtttgg actttggtta gaacccgaaa
     4681 tgatttctgt agatagtgat ttgtatcgtc aacatcctga ctgggctatt caggttcctg
     4741 attatgagca tacttattct cggaatcaat tagtacttaa tcttgccaat cctcaggtag
     4801 tagaatactt gaaaagtgtc ttagatcaac tcctatctta tcatgagatt gattacatta
     4861 aatgggatat gaaccgcaat atcactaagc tagggaatgg attaacttat ctagagacac
     4921 agatgcaatc tcatcagtac atgctgggac tttacgaact cgtttcttat ctgacagaga
     4981 agcacagcca tattctcttt gagtcctgct ctggtggtgg tggacgaaat gatcttggta
     5041 tgatacgcta tttcccacaa gtctgggcta gtgataatac tgatgccatt gcacgtttac
     5101 caattcaata cggttcatcc tatctctatc caaccatttc tatgggggct catgtgtcag
     5161 cagtaccgaa tcatcagatg ggacgaatga caccattaga aacacgtggc catgtagcaa
     5221 tgatgggaaa tttgggctat gagcttgatt tgacaaattt atcagatgaa gagaaagcta
     5281 cgattgctaa tcaggtgaac ttgtataaag aattacgacc agtagttcag ttaggacagc
     5341 agtatagact aattaatcct gatactgcat ccaatgaagc agctgtacaa tttaattacg
     5401 gaaatcaaac gattgtaacc tacgttcgcg ttttatctgt tgtagagacc atggaaacaa
     5461 ctttaaaatt aaaagatttg gatgaagagg gactatataa attacaggaa aatggcgaag
     5521 tttactcagg tgcagaacta atgtatgcgg gcttaactgt tatcttatcc caaggagatt
     5581 ttttgagtag acagtatatt tttagaaaac tatgatatgt actgacccca aaagttagat
     5641 ttattctgtc taacttttgg ggtgcagttc aataagggtg tataaattta taaaggaggc
     5701 tttctaatgg aatggtataa aaaaatcgga cttcttgcaa ctacaggttt agctttgttt
     5761 gggctcggcg cttgctccaa ctatggtaaa tctgcggatg gcacagtgac catcgagtat
     5821 ttcaaccaga aaaaagaaat gaccaaaacc ttggaagaaa tcactcgtga ttttgagaag
     5881 gaaaacccta agatcaaggt caaagtcgtc aatgtaccaa atgctggtga agtattgaag
     5941 acacgcgttc tcgcaggaga tgtgcctgat gtggtcaata tttacccaca gtccatcgaa
     6001 ctgcaagaat gggcaaaagc aggtgttttt gaagatttga gcaacaaaga ctacctgaaa
     6061 cgcgtgaaaa atggctacgc tgaaaaatat gctgtaaacg aaaaagttta caacgttcct
     6121 tttacagcta atgcttatgg aatttactac aacaaagata aattcgaaga actgggcttg
     6181 aaggttcctg aaacctggga tgaatttgaa cagttagtca aagatatcgt tgctaaagga
     6241 caaacaccat ttggaattgc aggtgcagat gcttggacac tcaatggtta caatcaatta
     6301 gcctttgcga cagcaacagg tggaggaaaa gaagcaaatc aataccttcg ttattctcaa
     6361 ccaaatgcca ttaaattgtc ggatccgatt atgaaagatg atatcaaggt catggacatc
     6421 cttcgcatca atggctctaa gcaaaagaac tgggaaggtg ctggctatac cgatgttatc
     6481 ggagccttcg cacgtgggga tgtcctcatg acaccaaatg ggtcttgggc gatcacagcg
     6541 attaatgaac aaaaaccgaa ctttaagatt gggaccttca tgattccagg aaaagaaaaa
     6601 ggacaaagct taaccgttgg tgcgggagac ttggcatggt ctatctcagc caccaccaaa
     6661 catccaaaag aagccaatgc ctttgtggaa tatatgaccc gtccagaagt catgcaaaaa
     6721 tactacgatg tggacggatc tccaacagcg atcgaagggg tcaaacaagc aggagaagat
     6781 tcaccgcttg ctggtatgac cgaatatgcc tttacggatc gtcacttggt ctggttgcaa
     6841 caatactgga ccagtgaagc agacttccat accttgacca tgaactatgt cttgaccggt
     6901 gataaagaag gcatggtcaa tgatttgaat gccttcttta acccgatgaa agcggatgtg
     6961 gattaggagt agagagacta tgaaaaaagt attacaaaaa tattgggcat gggcttttgt
     7021 ggtcatcccc ctcttgttac aagcaatttt cttctatgtg ccgatgtttc aaggagcctt
     7081 ttacagtttt accaactgga caggattgac ttataactac aaatttgtcg gcttaaacaa
     7141 ctttaagctc ctcttcatgg atccaaaatt catgaatgcg attggcttta ccgcaatcat
     7201 tgcgattgcc atggtggttg gtgagattgc actcgggatc ttcattgcgc gtgtcttgaa
     7261 ttctaaaatc aaaggccaaa ccttcttccg tgcttggttc ttcttcccag ctgttttatc
     7321 tggtttgaca gtggctttga tcttcaagca agtcttcaac tacggtcttc cagcgattgg
     7381 aaatgccctt catattgaat ttttccaaac cagtctttta gggactaagt ggggagcaat
     7441 ctttgcggct gtctttgtcc ttctttggca aggggtggct atgcccatca tcatcttcct
     7501 agctggtttg caatctattc caactgagat tacagaggca gcaaggattg atggtgcgac
     7561 tagcaagcaa gttttctgga acattgaatt gccttacttg ctaccaagtg tctctatggt
     7621 ctttatccta gccctaaaag gtgggctgac tgcctttgac caagtctttg ccatgaccgg
     7681 tggtggtcca aacaatgcca caacctcact tgggctcttg gtttataact atgcctttaa
     7741 aaacaaccaa ttcggttatg ccaatgccat tgccgtaatc ttgttcttct taattgtagt
     7801 gatttcgatc atccaattga gagtatctaa gaaatttgaa atttaagagg agaagcatga
     7861 tgaaacaaga tgaaagaaaa gccctgattg gcaaatacat tctattgatt ctaggatcgg
     7921 ttctgatttt agtgccgctc cttgctaccc tttttagttc cttcaaaccc actaaggata
     7981 ttgtagataa tttctttggc tttccaacca acttcacatg ggacaacttt agccgtctct
     8041 tagctgatgg gattggaggc tattattgga actctgtcgt catcactgtc ttgtctttac
     8101 ttgcagtaat gatctttata cctatggcag cctactccat cgctcgcaat atgagtaaaa
     8161 gaaaagcctt taccatcatg tataccctct taatcctcgg aatcttcgta cctttccaag
     8221 tcatcatgat tccgattacg gttatgatga gtaaactcgg tttggctaat acctttggtt
     8281 tgatcttact ctacttgacc tatgcgattc cacagaccct ctttctctat gttggctata
     8341 tcaaaatctc gattccagaa agtctggatg aagcagcaga gatcgatggg gctaatcaat
     8401 ttacaaccta tttccgcatc atcttcccaa tgatgaaacc gatgcatgcg acaaccatga
     8461 tcatcaatgc cctttggttc tggaatgact tcatgttgcc actccttgtc ttgaaccggg
     8521 attccaaaat gtggactctg cctttgttcc aatacaacta cgcaggccaa tatttcaacg
     8581 actacggacc aagctttgcc tcttacgtgg tcggcattat cagtatcacc attgtctatc
     8641 tcttcttcca acgccatatc atttcaggaa tgagcaacgg ggcagtgaag taatactcaa
     8701 tgaaaatcaa agagcaaact aggaagctag ccgcaggttg ctcaaaacac tgttttgagg
     8761 ttgtggatga aactgacgaa gtcagtaacc atacctacgg taaggtgaag ctgacgtggt
     8821 ttgaagagat tttcgaatag tataagaaga gctcatggaa tctatagtct ttgacacaga
     8881 ggaagagttc agcttgttga taattctatg tagaaaacaa gaaagtagta ctttgtttat
     8941 cacagtctat attagtacga gtttgatgat aaatagagat ttaaaatgaa ttttatttat
     9001 gaagccagat catatgagac ttggcttcaa ttagaaaaag gagagtaatg atgccgattc
     9061 agaataaaac aatgttgatt acctattcag atagtctggg aaataatctt aaagacttat
     9121 atgagaattt ggaagagtat tttggagatg atattggagg agttcacctt ctaccatttt
     9181 tcccatcaac aggtgatcgt ggatttgcgc cagttgacta cgacgaagtg gattcagctt
     9241 ttggtgattg ggaggatgtt aagcgtttag gtgagaaata ttatcttatg tttgacttta
     9301 tgattaatca tatttctcgt caatctaagt attataagga ctatcaagaa aaacatgaag
     9361 ccagtgaatt taaaggtctc tttttaaact gggataagtt ttggccagaa aaccgtccga
     9421 cacagtctga tgtagattta atttacaagc gtaaggatcg tgcaccaaag caagagattg
     9481 tgtttgaaga tggatcagtg gaacatttgt ggaatacctt tggtgaggag cagattgatc
     9541 ttgatgtgac caaagaagta actatggaat ttatccgtaa gaccattcag cacttggcaa
     9601 gtaatgggtg tgatttgatt cgtctagatg cctttgctta tgcagtgaag aaattggata
     9661 ctaatgattt ctttgtggaa ccagatattt gggatttatt ggacaaagtt cgagatatcg
     9721 ctgctgagta tgggacagag cttttacctg agattcatga acactattcg attcagttta
     9781 aaatagcaga ccatgattac tatgtttatg attttgctct tccaatggtg acactttata
     9841 ctctttacag ttccagaaca gagcgtttgg ctaagtggtt aaagatgagc ccgatgaagc
     9901 aatttacgac gctagatacc catgatggga ttggagtagt agatgtcaag gatatcctga
     9961 ccgatgagga gattgactat gcttcaaatg aactctataa ggttggagcc aatgtcaaac
    10021 gtaagtactc tagtgccgag tataacaact tagatatcta ccaaatcaat tcaacctact
    10081 attcagcgct tggagatgat gatgtcaagt attttctcgc tcgtctaatt caagcttttg
    10141 ccccaggtat tcctcagatt tactatgtgg gtctattagc aggcaagaat gacttgaaat
    10201 tattagaaga aactaaagaa ggtcgaaata ttaatcgtca ttactatagc aacgaggaaa
    10261 tagcaaaaga agtgcaacga cctgttgtga aggcccttct caatctattt tctttccgta
    10321 accgttcaga agcctttgat ctagaaggga ctactgagat agagacacca acagctcaca
    10381 gcattgtaat caaacgtcaa aataaagata agtccgtaac agcagtagta gaaattgatt
    10441 tgcaaaatca gacttatcgg gtaattgaga atggagttga agtatcattt tgaagccttg
    10501 atatggtgga taaaataggg tttttatttt ggaaaacgtt tcctttgttt tcaaattgct
    10561 aaaaaagtgg tacaatatag gatagcttac tattatctga atcagctgat ttggagagaa
    10621 aggattcatt ttgaaatcaa taggctttat tgaaaagctg aaggggttgt ctagtaaaga
    10681 gctgatttta ttgggaatta tcctgagtat ctttttaccc ttttatcttt ttgtagttgt
    10741 actctgttta tatattatca gtttgatttt tacaggagac atgaaaagta ttcttcagaa
    10801 aatgggggag catccgatgc tgcttctttt tcttagctat agtactgtta tatccattct
    10861 tgcacaaaat tggatgggtc ttgtggcttc agtaggaatg tttctattta ctattttctt
    10921 tttgcactat cagtcgattt tatcccataa attctttcga ttgattttgc agtttgtctt
    10981 gtttggtagt gtcttgtcag ctgcttttgc cagtttagaa catttccaaa ttgtgaagaa
    11041 atttaactat gcttttcttt cacccaatat gcaggtgtgg catcagaacc gggcagaagt
    11101 gaccttcttt aatcctaatt attatggaat tatttgttgt ttctgtatta tgattgcttt
    11161 ctatctgttt acaacgacca agttgaattg gttgaaagta ttctgtgtga ttgcaggctt
    11221 tgttaatctc tttggtttga actttactca aaatcgaact gcctttcctg ctattatcgc
    11281 tggagcaatt atctatctct ttacgactat taaaaactgg aaggcctttt ggcttagtat
    11341 tggggtcttc gcgattggtt tgagtttcct cttttctagt gatttgggag ttcgaatggg
    11401 tactttagac tcttctatgg aagaacgcat ttctatctgg gatgctggga tggccttgtt
    11461 taagcaaaat cctttttggg gtgaagggcc attgacctat atgaactctt atcctcggat
    11521 acatgctcct tatcatgaac atgcccacag tctttatatt gatacgattc tgagttacgg
    11581 aattgtgggg actattttat tagttttgtc ttctgttgct cctgttcgct tgatgatgga
    11641 tatgagtcag gagtcgggga aacgtccgat tatcggcctt tatctatctt tccttacagt
    11701 ggttgctatg cacggaattt ttgacttggc tctcttctgg attcagtcag gctttatttt
    11761 cttgctagtt atgtgcagta ttccattgga gcatcgaatg ttggtatcgg acatgacgga
    11821 ttaagtttta taagtttgaa atcttctacc ttgggtagga gattttttat acgatgggca
    11881 tgtcgtgcat ctgaggtgta agtcctctgt agggctccac taccggtgaa tacaatagcg
    11941 ctccccaagc ctgactatcg tgaggtagcg gattaaaatg gtctggggat agatcgtttt
    12001 aagtctgacg caggaaataa gaattgtcag agaaagcaat agtgaaatcg taggctatga
    12061 atagaaacgt gatagcgagg agcatatagt ggataaggta gcgagaaatt ttaaagtata
    12121 aaagatagtc ttaatctata tatgtaaatc acaaaagtaa ttgaattcgg gataaggttg
    12181 gtgtgaaaag acatagtaaa ctgaatcttg aatactagaa tgatacttct acaatattgt
    12241 tataatttaa tttgaattcc aaaatcacat tgttccgtcc gtatttcatt ttactgtatg
    12301 tcttcctaaa ctccaaagtt tctgcgtcaa atttcctatt ttcactgtag tctttgacac
    12361 ttcgaacgac aatttgaatc atatattcaa aaaaaatgaa aaatttgtgc caacaagcct
    12421 aaatattctg aaaatttgtt tgatttttaa tggataatgt gatataatgg ttgtcaatct
    12481 ataattcaca taaacagagg agtagaaaat gaaaaaaaat cgtgtatttg ctacagcagg
    12541 tcttgtttta ttagcagcag gtgtacttgc agcatgcagt tcttcaaaat catctgattc
    12601 atcagcccct aaagcttatg gctatgttta tacagcagac ccagaaacct tggactacct
    12661 gatttcaagt aaaaatagta caacagtagt gacttcaaat gggattgatg gtttattcac
    12721 taacgataat tacggtaatc ttgctcctgc agttgcagag gattgggaag tctctaagga
    12781 tggtttgacc tacacttata agattcgtaa aggggttaaa tggtttacct ctgatggaga
    12841 agaatatgca gaggtgacgg ctaaagattt cgtgaacggt ttaaaacacg cagcagataa
    12901 aaaatcagaa gctatgtatt tagctgaaaa ttcggttaaa ggcttggcag attatctatc
    12961 aggaacttca acagattttt caacagttgg tgtcaaggcg gttgatgatt atacgttaca
    13021 atacactttg aaccagcctg aaccgttctg gaactctaag ttgacctatt ctattttctg
    13081 gcctctgaat gaagaattcg aaacatcaaa aggaagcgat tttgctaaac caacagatcc
    13141 gacatccttg ctttataatg gtccattctt gttgaaaggg ttgactgcaa aatcttctgt
    13201 agagtttgta aaaaatgagc aatattggga taaagaaaat gtccacctag atactatcaa
    13261 tctagcttac tatgatggat cagatcagga gtcgctagag cgtaacttca ctagtggagc
    13321 ttatagttat gcccgtcttt accctaccag ctccaactat tctaaggttg cagaagaata
    13381 caaggacaat atctattaca cacaatcagg ctctgggatt gctggtctgg gtgtgaatat
    13441 tgatcgccaa agttacaact atacttctaa aactacagat tcagagaaag tagctactaa
    13501 gaaggcattg cttaacaaag atttccgtca agccttgaat tttgctcttg atcgctcagc
    13561 ttactcagct caaatcaatg gtaaagatgg agcagcttta gcagttcgta atttatttgt
    13621 aaaaccagac tttgtttcag ctggtgagaa gacctttggt gatttagtcg ctgctcaact
    13681 tcctgcttat ggtgatgagt ggaaaggtgt gaatttagct gatgggcagg atggtttatt
    13741 caatgctgac aaggccaagg cagagtttgc gaaagctaag aaagctttag aagcagacgg
    13801 cgttcagttt cctattcatc tggacgttcc agtagaccaa gcatcaaaaa actacatatc
    13861 tcgtattcag tcctttaaac aatctgtaga aacagttctt ggtgttgaaa atgtcgttgt
    13921 tgatattcaa caaatgacaa gtgatgaatt ccttaatatt acttactatg ctgccaatgc
    13981 ttcatctgag gattgggatg tatcaggagg agtttcatgg gggccagact atcaagaccc
    14041 atctacttac ctggatattt taaaaacaac tagcagtgaa actacaaaaa catatttagg
    14101 atttgataat ccaaatagcc cttcagtagt tcaagttggt ttgaaagaat acgataaatt
    14161 agttgatgaa gctgccagag agacaagcga cttgaatgtc cgttatgaaa aatatgcagc
    14221 ggctcaagca tggttgacag atagttcact ctttattcct gctatggctt cttctggtgc
    14281 agcaccagtg ctttcacgaa ttgttccatt tactggagct tctgcgcaaa caggctctaa
    14341 ggggtcagat gtttacttca aatatttgaa attacaagat aaagtggtga ctaaggaaga
    14401 gtatgaaaaa gctcgtgaaa aatggttgaa agaaaaagct gaatcaaatg agaaagctca
    14461 aaaagaattg gcaagtcatg tgaagtaaat aatttctaat agaactttct ctccatgagg
    14521 agaaggttct tttgggattt ttaaaggaaa taatatgaaa aaatatattt ttatgcgtgt
    14581 tttgcggtca ttggtttcga ttttcttagt aacgactttg acctacacga ttatctatac
    14641 cttggttcct cgaaaattga ttttcaagca ggatcctaac tataataaaa ttgcgacaac
    14701 ggctgataaa cgtgataact atgaaaatac tgtgtttgag cgtatgggct acattgagta
    14761 ttacgatact aaagagttgc aagaaaaggc aagtagcatg gattcttctg taacagtaga
    14821 agcaaatgcg accaataaag ctatttatga aaagtacatc aatcaattag gtcatggttg
    14881 gactttggga gaatttactg aaagtggtca attctatgct actcgtgaaa ttccaatttt
    14941 tgaacgtgtt tttcacttct atgctaactt gattgacatt gaccatacaa ataaaatcca
    15001 agaccctgaa aatccagact tgaaacgcta ccttcgtttt gaaaatgatc cagctatcgg
    15061 atggtcattg gtcggttcag gaactaaaca taaatatctc ttgtacttta acagtcagtt
    15121 cccatttgtt catcaaaact ttgtgaactt gaatttaggt gactcttacc caacctatgc
    15181 taatacacca gttcttcagg ttattactca aggtcaagga caaaccaaaa ctgcccaagt
    15241 tcagttccca acaggtaaga aaacgtcttc tgtaaatatt tactcaagaa cctacaagtc
    15301 acctagtcag gctgactctc gtgaagtagc tagctatggg aaagatgatc cttatacagc
    15361 gactgaaagt aattaccaat atccatctat gattgtcagc tctgctatta ctggtttgat
    15421 tggtttggtt cttgcctatg ctcttgccgt gccacttggt tcagccatgg ctcgtttcaa
    15481 gaacacttgg attgatagcc tctcaacagg ggctttgacc ttcttgcttg ctcttccaac
    15541 gattgccttg gtttacatcg ttcgattgat tggatcatct attgcccttc cagattcatt
    15601 ccctatcttg ggagctggag attggcgttc ttacgtttta ccagcagtca tccttggttt
    15661 gttgggtgct cctggtacag ccatttggat tcgtcgttac atgattgact tgcaatctca
    15721 agactttgtt cgtttcgctc gtgcaaaagg tttgtctgaa aaagaaattt caaacaaaca
    15781 catctttaaa aatgccatgg ttccgctggt ttcaggaatt cctgctgcca ttattggggt
    15841 tatcggtggt gcaaccctta ctgaaacagt cttcgccttc ccaggtatgg gtaaaatgtt
    15901 gattgactct gtaaaagcat ctaataactc tatggtcgtt ggtcttgtct tcatctttac
    15961 atgtatttct atcttctcac gtcttttggg agatatttgg atgactatta ttgacccacg
    16021 tattaaattg actgagaaag gaggcaaata atgtctacaa tcgataaaga aaaatttcag
    16081 tttgtaaaac gtgacgattt tgcctctgaa actattgatg cgccagcata ttcttactgg
    16141 aaatcagtgt ttaaacaatt tatgaagaaa aaatcaactg tagtcatgtt gggaatcttg
    16201 gtagccatca ttttgataag tttcatctac ccaatgtttt ctaagtttga tttcaatgat
    16261 gtcagcaagg taaacgactt tagtgttcgt tatatcaagc caaatgcgga gcattggttc
    16321 ggtactgaca gtaacggtaa atcgctcttt gacggtgtct ggttcggagc tcgtaactcc
    16381 atcctcattt ctgtgattgc gacagtgatt aacttggtta tcggtgtttt tgtcggtggt
    16441 atttggggta tttcaaaatc agttgaccgt gtcatgatgg aagtttacaa cgtcatctca
    16501 aacatcccac ctcttttgat tgttattgtc ttgacttact caatcggagc tggattctgg
    16561 aatctgattt ttgccatgag cgtaacaaca tggattggta ttgccttcat gatccgtgtg
    16621 caaatcttgc gctatcgtga cttggaatac aacttggcgt cacgtacttt gggaacacca
    16681 accttgaaga ttgttgccaa aaatatcatg cctcaattgg tatctgttat tgtgacaacc
    16741 atgactcaaa tgcttccaag ctttatctca tacgaagcct tcttgtcttt cttcggtctt
    16801 ggattaccga ttacagtgcc aagtttgggt cgtttgattt cggattattc acaaaacgta
    16861 acaaccaatg cttacttgtt ctggattcca ttgacaaccc ttgtcttggt atccttgtcc
    16921 cttttcgtag ttggtcaaaa cttagcggat gctagtgatc cacgtacaca tagataggag
    16981 tagaaatgac aaaagaaaaa aatgtaattt tgactgctcg cgatattgtc gtggaatttg
    17041 acgttcgtga caaagtattg acagccattc gcggcgtttc ccttgaacta gtcgaaggag
    17101 aagtattagc cttggtaggt gagtcaggat caggtaaatc tgttttgaca aagaccttca
    17161 caggtatgct cgaagaaaat ggtcgtattg cccaaggtag tattgactac cgtggtcagg
    17221 acttgacagc tttatcttct cacaaggatt gggaacaaat tcgtggtgct aagattgcga
    17281 ctatcttcca ggacccaatg actagtttgg accccattaa aacaattggt agtcagatta
    17341 cagaagttat tgtaaaacac caaggaaaaa cagctaaaga agcgaaagaa ttggccattg
    17401 actacatgaa taaggttggc attccagacg cagatagacg ttttaatgaa tacccattcc
    17461 aatattctgg aggaatgcgt caacgtatcg ttattgctat tgcccttgcc tgccgacctg
    17521 atgtcttgat ctgtgatgag ccaacaactg ccttggatgt aactattcaa gctcagatta
    17581 ttgatttgct aaaatcttta caaaacgagt atcatttcac aacaatcttt attacccacg
    17641 accttggtgt ggtggcaagt attgcggata aggtagcggt tatgtatgca ggagaaatcg
    17701 ttgagtatgg aacggttgag gaagtcttct atgaccctcg ccatccatat acatggagtc
    17761 tcttgtctag cttgcctcag cttgctgatg ataaagggga tctttactca atcccaggaa
    17821 cacctccgtc actttatact gacctgaaag gggatgcttt tgccttgcgt tctgactacg
    17881 caatgcagat tgacttcgaa caaaaagctc ctcaattctc agtatcagag acacattggg
    17941 ctaaaacttg gcttcttcat gaggatgctc cgaaagtaga aaaaccagct gtgattgcaa
    18001 atctccatga taagatccgt gaaaaaatgg gatttgccca tctggctgac taggaggaag
    18061 gaaatgtctg aaaaattagt agaaatcaaa gatttagaaa tttccttcgg tgaaggaagt
    18121 aagaagtttg tcgcggttaa aaatgctaac ttctttatca acaagggaga aactttctcg
    18181 cttgtaggtg agtccggtag tgggaaaaca actattggtc gtgctatcat cggtctaaat
    18241 gatacaagta atggagatat catttttgat ggtcaaaaga ttaatggtaa gaaatcgcgt
    18301 gaacaagctg cggaattgat tcgtcgaatc cagatgattt tccaagaccc tgccgcaagt
    18361 ttgaatgaac gtgcgactgt tgattatatt atttctgaag gtctttacaa tcaccgttta
    18421 tttaaggatg aagaagaacg taaagagaaa gttcaaaata ttatccgtga agtaggtctt
    18481 cttgctgagc acttgactcg ttaccctcat gaattctcag gcggtcaacg tcaacgtatc
    18541 ggtattgccc gtgccttggt catgcaacca gactttgtta ttgcagatga gccaatttca
    18601 gccttggacg tttctgtacg tgcccaagtc ttgaacttgc tcaaaaaatt ccaaaaagag
    18661 ctcggcctga cctatctctt catcgcccat gacttgtcgg ttgttcgctt tatttcagat
    18721 cgtatcgcag ttatttacaa gggtgttatt gtagaggttg cagaaacaga agaattgttt
    18781 aacaatccaa ttcacccata tactcaagcc ttgctttcag cggtaccaat cccagatcca
    18841 atcttggaac gtaagaaggt cttgaaggtt tacgatccaa gtcaacacga ctatgagact
    18901 gataagccat ctatggtaga aatccgtcca ggtcactatg tttgggcgaa ccaagccgaa
    18961 ttggcacgtt atcaaaaagg actaaactaa taatggtttt ataatttcca tgtcaatttt
    19021 tatgggaatt ataaaacttt ttttgttgga ctgatttgaa aaactttgaa agcttcctga
    19081 aagaattttc gaaaaatttt aaaaaatttt gaaatattat tgacaggtga tgaaaaaggt
    19141 ggtaggatag gaaggatcaa aaaagaaagc agaaaaagaa atgaataaga gacaagccgt
    19201 aactatgaat caaaactttt actttagcta ctttagatag tgtttgtaga catgtcacca
    19261 tggatgcaaa cagttcaagc aatttgtttg tatctatgtg gctaagattt ttgattgtgg
    19321 tccatataga tgaatatcta aatggactag ctaagttgta acttgttagg ttatttcaag
    19381 tacccgttta gatagtatct aggcggtttt ttgttttatc ttttctgaga aggagtttca
    19441 ttatgaaagt tgttcgaaaa tcactagccc cctcttggta gtggggatcc tcttgacttc
    19501 tctgatcagt ttgcatcagt tgaaggcaga taagaaaaga gatgtctttc gtatcggtat
    19561 ttcgcagttt attacccacc agtccttaga cgctactaga gaaggatttg tggatgagct
    19621 ggccaaacaa ggctatgttg agggggaaaa tattgagatt gatttgcaaa atgcacaggg
    19681 agaacaaaga aatctaaaaa cgatttccca gcaactagca gaatccagcg atgtcgttct
    19741 agccatcgca aggccttctg ctcagagctt ggccaatacg acgcaaacga caccagttat
    19801 cttttcagct gtaacagacc cagtcagtgc caagttggtt gagtcaagag aacatcctgg
    19861 gggcaatgta actgggacaa gcgatcagtc atcagatgcc atttcaaccc aaatcaattt
    19921 gataaagaaa gtgttgccaa aggctaaaac gattggaatc ctctatactc agagcgagcc
    19981 caattcggtt gtttaaaatg atgaagctaa gcgacttctg aaagaaaaag gctttaccgt
    20041 tgttgaaaaa acaatcttgg acagtaataa cgtcaaggcg gcagcagaga gtttgatggc
    20101 agaggtggat atggtttttg tcccaactga taatatcatt tcgtcaacca tggaaacagt
    20161 taagcaggtt tctattaaac acaaggttcc agtattcggt ggttcaacag aaatgattgc
    20221 tgttggtgac ttgtataact acggaaccaa ttatgaagaa ttgggaagac agacagctcg
    20281 catgctgatt cgtgttttaa aaggtgagaa accagaaaat atagcagttg agttgcctga
    20341 aaaactggaa ttgcatacca atcaagaaat ggcagatgca ttgggaattg atattagtaa
    20401 gttagaaggc aaggaataag gaggattaag atgaattttg tgttatctag tttatcagaa
    20461 ggtttgttgt ggtcgattgt ggcgattggg gtctacttga ctttccgtat tttggatatt
    20521 gcggatataa ctgctgaggg agcctttcct ctgggggcag cagtcgttgt atcacagata
    20581 caggcagggg caaatccttg gcttgcgact ttacttgctt tgctggcagg tatggtagca
    20641 ggtcttgtat caggaatgct ccacaccaag atgaaaatcc cagctctctt gacagggatt
    20701 gtgaccttga cagggctcta ttcaatcaat attaaaatta tgggcagtgt acccaatctt
    20761 tccttgggag attctgcaac cgtctttaaa cagttggcga gcttgggtct gacaaatgaa
    20821 ggagctgttt tctcacttag tttagtctgt ctcttacttg tttggtcttg acccttttga
    20881 tgaaaacaga gattggtttg gtcttgcgtt cgactgggga taatatcccg ataagtgagg
    20941 ccaatggagt caatgtagac accatgaaga ttgttggtta catgatttca aacggtttga
    21001 ttgccctatg tggttccttg tttgcccaaa atgatggatt ttcagatgtg acttctggga
    21061 caggaaccat tgttgttggt ttgagctcgg aagtcttgat acacgacttg accattggag
    21121 gccgcttatt atccatcgga atcggtgcta ttgtttaccg tttgattatt ttaaatatct
    21181 atgaaattcc aaatctagat caaaacttgg tacgtctctt taatgcaatc ttgctcgctt
    21241 tggttttatt tgcaccagaa ttgcaaaaga gattaaagat tcgtggtctg aaattgagaa
    21301 atgaatagga ggagaaagtt atggcaagtt tgttaacact tgaaaatatt cacaagacat
    21361 ttgaagcagg gacggtcaat gagaaccatg tcctcaaagg attagattta gaggttgaag
    21421 agggagattt tatctatgtg attggtggaa atggagcagg aaaatccact ttgatgaata
    21481 tcttggctgg caatctatcg gtggacgaag gggaccttct actggcaggg aaatccatta
    21541 aaaatctgag tgtcagaaag agagccaagg atattgcccg tgtttttcaa tatcctaaga
    21601 tgggaacagc ttctcgtttg acgattgagg agaatatggc tattgccttg agacgtgggc
    21661 aaaagagagg gcttggttgg ggtgtgaagg agaaggatag aatccagttc caagaggcct
    21721 tgaaggagtt gaatattggt cttgaaaacc gcttaaaagt agatactcaa tatctctcag
    21781 gaggacaaag acaggctttg accctagtca tggcagctct ggtgaaaccc aaacttttac
    21841 ttttggatga acatactgcg gcacttgacc cgaaaaccag tcaaatggtg atggacttga
    21901 cgcaaaagat tgtggagcac catcagtgga cgactttgat gattacccat gatatgaatc
    21961 atgcgattga gtacggcaat cgtctcatta tgctctatca aggcaagata gtggtggatg
    22021 tcaagggaga agagaaaaag catctgacag ttgaagacct tatgcatctc ttccagaaaa
    22081 atagtggcca aagtctggtc agtgatgaat tagttttggg ataaagaaaa aggctgagat
    22141 ctggtgtctc agtcttttat ttcttgcgtt ttgcaaaatc tacaaatcta aatttttcta
    22201 acttatggcg actttcggta aactgaaatt ggcgtccgtc ttggagatag acttttgatt
    22261 taatcgaaac gacataaggg tctttgccaa tgtccatgag aatcttgtct cggtcgcttg
    22321 agtggtcaat ggtgatttcc ttctgagcat aatcaataag gagtttgagg ccattttcta
    22381 tataagaata gatagactgc tcagcaattt ggcgagtgag atttgggatg agttccatat
    22441 ccagatagtc cgtatccaga acggatacca gatcatccac cacacgctgg cggaccacct
    22501 tccaaaccat ccgaaactct gggaaaccgg ttatcagtga ggatttttta tcaataataa
    22561 tcttgtccag actgaccacg ttggttttag agcgcagtcc aagttcttta actagttctt
    22621 ggtagctggt taggttggat acagggaaat tgacggtttc ttctttgacg acttgagaac
    22681 cttgccctct tatctttttg atcaatcctt cctcttggag gagagacagg gcctttcgga
    22741 cggtatcacg actcacttga tattgctcca taaggtcgtg ctcgctagga aggaaatctc
    22801 cgacagcgta agtctcgttt tgaatggttt cttggatttg cttaaataat tgttggtatt
    22861 tcttcatttt gcctgcttta ataggttttt agtctagttt aatgaacacc tgtatctatt
    22921 ttaccataca agtgctagaa aatttacaaa aaaacaccct ttttatacca aacaagttgc
    22981 agacaagttt ggtatcgttt acgatatact tatcaaatca aacttgcttt gacaagtata
    23041 aggagaatca aatgggaaaa tttgaacaag aagccaaaga tctgcttcag gcaattggag
    23101 gcaaagaaaa tgtgactgcc gtaactcact gtgcgacacg gatgcgcttt gttttaggag
    23161 atgataagaa ggctaatgtt aaagctatcg agtcaattcc agctgttaaa ggaactttta
    23221 caaatgcagg tcaatttcag gtaatcattg gaaatgacgt gcccatcttt tataatgatt
    23281 ttacagccgt ttcaggtatt gagggtgttt ccaaagaagc agccaagtct gcagctaaga
    23341 gtaatcaaaa cgtggtccaa cgtgttatga ccactctggc ggagattttt actccgatta
    23401 ttccagcctt gatagtcgga ggattgatcc tcggtttccg taatgtcttg gaaggtgtcc
    23461 attggtcgat gttggatggc aagaccatca cagaatcctc tcagttttgg gcaggtgtca
    23521 atcacttcct atggttgcct ggtgaagcta tcttccagtt cttaccagta gggattactt
    23581 ggtctgtttc tcgtaagatg ggaaccagcc aaattttggg aattgttctc ggaatctgtt
    23641 tggtatcgcc tcagttgctc aatgcctatg cggttgcttc aacgccagca gctgatatcg
    23701 cggcaaactg ggtttggaat tttggctatt ttactgttaa tcgtatcggt taccaagccc
    23761 aagttatccc agccttgctt gcaggtttga gtctgtctta tcttgaaatc ttctggcgca
    23821 agcatatccc agaagtcatt tctatgattt ttgtaccttt cttgtcattg attccagcct
    23881 tgattttggc tcatactgtt ttgggaccaa tcggttggac aattggacaa ggactttcat
    23941 cagttgtctt ggcaggttta actggtccag ttaaagggct cttcggtgca atttttggtg
    24001 ccctctacgc tccatttgtc atcacaggtc tgcaccatat gaccaatgcc attgatacac
    24061 aattgattgc ggatgctggt ggcactgccc tatggccaat gattgctctt tctaatattg
    24121 ctcaaggctc agccgtgttt gcctattatt tcatgcatcg ccatgatgag cgtgaggctc
    24181 aggtttcact tcctgcaacc atttcagcct atctcggtgt tacagaacca gctctttttg
    24241 gggttaacgt aaaatatatt tatccatttg ttgctgggat gactggttca gcccttgcag
    24301 gcatgttatc cgttactttt aatgtaactg cggcttctat tggtatcggt ggtttgccag
    24361 gtattctctc tattcaacct caatacatgc tgccatttgc aggaactatg ctagttgcga
    24421 ttgttgttcc aatgctcttg actttcttct tccgcaaggc tggtctcttt acaaaaacag
    24481 agggcgatac gaacttgcag gcagaattcg ttgctcaaga agaagcagaa tttgtgaacc
    24541 atgaaccagt agaacttact tcggtagaaa ttatcagccc actaactggc caagtgaaag
    24601 aattgagtca agcgacggat cctatttttg catcaggtgt catggggcaa ggtctggtca
    24661 ttgaaccaag ccaaggtgag ttgacctctc cagttaatgg gacagtgacg gttcttttcc
    24721 ctaccaagca tgccatcggc attgtctctg acgagggagt tgaattgctc atccacatcg
    24781 gtatggatac agtaggtctt gatggcaaag gttttgaaag tcttgtagtc caaggagatc
    24841 acgttacagt tggtcagcaa ctgattcgtt ttgatatgga tgtcattaag gctgcaggtc
    24901 tggtgacaga aactcctgtt atcatcacca accaagatgc ttatacagcg actattcccg
    24961 gaacttatcc gacaacgatt caagctggag catctctcat ggtcgctaca cgaatctaat
    25021 actcttcgaa aatctcttca aaccacgtca gctctatctg caacctcaaa acagtgtttt
    25081 gagcaacctg tggctagctt cctagtttgc tctttgattt tcattgagta taattgaaat
    25141 agcacaaata gggacggaag actgcttcct cccttttatc agaaaaggag aaacagatga
    25201 cacttgataa aggaaaagta gtctatcaaa tctatccaaa atcttacaaa gacaccactg
    25261 gcaatggtat tggggatttc cgtgggatta tcggaaaaat tccctatcta gccaaactag
    25321 gtgtggatat ggtctggctc aatccattct atccaagtcc tcaacgggat aatggttacg
    25381 atatttcaga ttatatggca gtggatcctc tttttggtga tatggctgat tttgaggaaa
    25441 tggtgtgtat cggtaaagag cacaagattg actttatgct ggacatggta cttaatcatt
    25501 gttcgacaga gcatgaatgg tttcagaaag ccctagctgg tgataagtat tatcaagact
    25561 ttttcttcat ccaagaccaa ccaacagatt ggcagtctaa gtttggtggt tctgcatggg
    25621 cgcctttcgg ggatactggg aaatactatc ttcacctatt tgatgagacc caggctgacc
    25681 ttaactggcg caatcccaat gtccgtaagg agcttttcaa ggttgttaat ttctggcgcg
    25741 acaagggtgt caaaggtttt cgatttgatg tgatcaattt gattggtaag gacgaggttt
    25801 cagtggactg tcctgaaaat gaagggaagc cagcttatac agacaaaccc atcgttcata
    25861 actatttgcg tatgatgaac caagccactt ttggatctga cgatagcttt atgacagttg
    25921 gggaaatgtc ttctaccacc atggaaaact gtgtcctcta ttcgtcgcct gatcgtcagg
    25981 aattatccat gacctttaat tttcatcacc tcaaggtgga ctataaggat ggacaaaagt
    26041 ggaccttggc tccctttgat tttgaagagt tgaagagtct ttaccatagt tggggtaagg
    26101 aaatgagtga taaagacggt tggagtgccc tcttttggaa caatcacgat caaccacgtt
    26161 ccttgaaccg ttttgtcgat attcaaaact tccgcaagga aggagccacc atgctagcag
    26221 ccagcattca cctgtcacgt gggacacctt atatctacat gggtgaggaa atcgggatga
    26281 ttgacccaga ctatgattct atggctgatt atgtggatgt cgaatcgctt aatgcctatc
    26341 agatgctctt agaagaagga aagagtcagc aagaagcctt ccagattatt caagctaagt
    26401 cgcgtgataa ttcacgcatt cccatgcagt gggatgcttc ggaaaatgca ggattttcaa
    26461 caggcactcc ttggttgaaa gctggtaaat cctataaata catcaatgta gaaaatgaaa
    26521 tccagggtcc gatttttacc ttctatcaag acttgattcg actgcgtaag gaaatgccaa
    26581 tcatttcaga aggaagttac aaaccagcct ttgaagatag caaacaagtc tacgcttttg
    26641 aacgccagtt tgaggatcaa aagttactag tgctcaataa cttttatgct aaagaagtgg
    26701 aaatcgactt gccagcagtc taccaaaatg gacagatttt gatatcaaac tatgaagatg
    26761 cagaagtgtc tgagaaaatt ctactcaaac cctatcaaac actggctatt tatgtaaatt
    26821 aatactcttc gaaaatctct tcaaaccgtg tcagttttat ctgcaacctc aaagcggtgc
    26881 tttgagcaac ctgtggctag cttcctagtt tgctctttga ttttcattga gtataaactt
    26941 agcaaggaga cctctttttc agaaaagcag cgttcttttt gctgtctatt ccatccctga
    27001 aagtgtagaa caaactggtc agggtggcta gtttgtggta taatgaaagg gattcaaaaa
    27061 gaaacaggag aaaaatgatg gatttacttt tagcaattgt attgattgtg ctagcttttc
    27121 taggaggagc tcttggagga atgtacttgg ttcgtaagca aatcgaaaaa gaatttgctg
    27181 acaacccacg tttgaatgct gaagcagttc gtactctttt gagtgcaaat ggtcaaaaac
    27241 caagcgaagc taaggtacaa caagtttacc accaaatcat ccgccaacaa aaggcagccc
    27301 ttgctaacaa taaaaagaaa aaataaataa ggaaaagtct gggatgaaag ttccagactt
    27361 ctcactatgt tggttatggt ttagggatga gactttttcc ttgcattcta ttgatatttg
    27421 attatgatta agagagaggt agttgacatt ctatcaagct gtcggtcagt tcgttcagta
    27481 caaggaatca taatgaacga tcaatcagaa aaaagactag aaagaagact gtatggataa
    27541 tcgaccaatt ggttttttgg attcgggtgt cgggggcttg accgttgtgc gcgagctcat
    27601 gcgccagctt ccccatgaag aaatcgtcta tattggagat tcggcgcggg cgccctatgg
    27661 cccccgtcct gctgagcaaa ttcgtgaata tacttggcag ctggtcaact ttctcttgac
    27721 caaggatgtc aaaatgattg tcattgcttg taacactgcg actgcggtcg tctgggaaga
    27781 aatcaaggct caactagata ttcctgtctt gggtgtaatt ttgccaggag cttcggcagc
    27841 catcaagtcc agtcaaggtg ggaaaatcgg agtgattgga acgcccatga cggtacaatc
    27901 agacatatac cgtcagaaaa tccatgatct ggatcccgac ttacaggtgg agagcttggc
    27961 ctgtcccaag tttgctccct tggttgagtc aggtgccctg tcaaccagtg ttaccaagaa
    28021 ggtggtctat gaaaccctgc gtcccttggt tggaaaggtg gatagcctga ttttgggctg
    28081 tactcattat ccactccttc gccctattat ccaaaatgtg atggggccaa aggttcagct
    28141 catcgatagt ggggcagagt gcgtacggga tatctcagtc ttactcaatt attttgaaat
    28201 caatcgtggt cgcgatgctg gaccactcca tcaccgtttt tacacaacag ccagtagcca
    28261 aagttttgca caaattggtg aagaatggct ggaaaaagag attcatgtgg agcatgtaga
    28321 attatgacaa ataaaattta tgaatataag gatgaccagg actggtatgt tgggtcttat
    28381 agtatttttg gtggcgttaa cagtttgagc gactatcaga cagattttcc tctgtttgaa
    28441 ttctccaaaa tatttggaga tgaagagtat ggtttcccgc tttcagttac tgttttacgc
    28501 tatggttcta cctaccgttt gttctccttt gtggtagata tgcttaatca agaaatggga
    28561 cgaaacttgg aagttattca acgtcatggg gccctgctct tggttgaaaa tgggcaactc
    28621 ttgtatgtag aattgcctaa agaaggggtc aatgttcatg atttctttga gacaagcaag
    28681 gtcagagaaa ccttgttgat tgcgactcgt aacgaaggta aaaccaagga attccgagct
    28741 atctttgata agttaggcta cgatgtggaa aatcttaatg actaccctga cctgcctgaa
    28801 gtagcagaaa caggtatgac ctttgaggaa aatgcccgcc ttaaggcaga aaccatttct
    28861 caattaacgg gcaagatggt tttggcagat gattctggtc tcaaagtcga tgtccttggt
    28921 ggcttaccag gcgtctggtc agctcgtttc gcaggtgtgg gagcaactga tcgtgaaaat
    28981 aatgccaaac tcttgcacga attggccatg gtctttgaac tcaaggaccg ctcggctcag
    29041 ttccacacaa ccctagtcgt agccagccca aataaggaaa gtttagttgt tgaagcagac
    29101 tggtcaggtt atattaactt tgaacctaag ggtgaaaatg gctttggcta tgatcccctc
    29161 ttccttgtag gagagacagg tgagtcatca gctgaattaa ccctggaaga aaaaaatagt
    29221 caatctcacc gtgccttagc cgttaagaaa cttttggagg tatttccatc atggcaaagc
    29281 aaaccatcat tgtaatgagc gattcccatg gcgatagctt gattgtggaa gaagtccgtg
    29341 atcgctatgt gggcaaagtc gatgccgttt ttcataacgg cgattctgaa ctacgtccgg
    29401 attctccact ttgggagggc atccgcgttg ttaaagggaa catggacttc tacgccggct
    29461 acccagaacg tctggtgact gagcttggtt cgaccaagat tatccaaact catggtcact
    29521 tgtttgacat caatttcaac tttcaaaagt tggactactg ggctcaggag gaagaggccg
    29581 ctatctgcct ctatggtcac ttgcatgtgc caagtgcttg gttggaaggc aagatcctct
    29641 ttctaaatcc aggctctatc agtcaaccac gaggtaccat cagagaatgt ctctatgctc
    29701 gtgtggagat tgatgatagt tacttcaaag tggacttttt gacacgagat cacgaggtgt
    29761 atccaggttt gtccaaggag tttagccgat gattgccaag gagtttgaga ctttcttgtt
    29821 ggggcaggag gaaacttttt tgacccctgc taaaaatcta gctgtgttga ttgatactca
    29881 caatgcggat catgcgaccc tcttgctcag tcagatgacc tatacccgtg ttcccgttgt
    29941 gacagatgaa aaacagtttg ttgggacgat tggactcaga gatattatgg cttatcagat
    30001 ggagcatgac ttgagccaag aaatcatggc ggatacggat atcgttcata tgacaaaaac
    30061 ggacgtagcg gttgtttcgc ctgatttcac cattacggag gtcttgcaca agctagtaga
    30121 tgagtccttc ttaccggttg tggatgcaga gggtattttc caagggatta ttacgcgcaa
    30181 gtccatcctc aaggccgtta atgccctctt gcatgacttt agtaaggaat atgagattcg
    30241 atgccaatga gagacaggat ttcagccttt ttagaggaaa agcagggctt gtctgtcaat
    30301 tccaagcagt cctataagta tgatttggag caatttttag acatggtagg tgagcggatt
    30361 tctgagacca gtctcaagat ttaccaagcc cagctagcca atctaaaaat cagcgcccag
    30421 aagcgaaaga tttcggcctg taaccaattt ctatactttc tctatcaaaa aggagaggtg
    30481 gacagctttt accgcttgga attagccaaa caagctgaaa agaagacgga aaagccagag
    30541 attctatacc tagactcttt ttggcaggaa agcgaccatc cagagggccg cttgctagcg
    30601 ctcttaatcc tagaaatggg gctcttgccc agtgagattt tagccatcaa ggttgcggac
    30661 atcaatctgg attttcaggt gttgcgaatc agcaaggctt cccaacggag gattgtcacc
    30721 attcccacgg ccttgctttc agaattggaa cccttgatgg ggcagaccta tctttttgaa
    30781 agaggaggga aaccctattc tcgtcagtgg gcctttcgtc agttagaatc ttttgtcaag
    30841 gagaaaggtt ttccatcctt atcagctcaa gtcttacgtg aacagtttat tctaagacaa
    30901 atagaaaaca aggtcgattt gtacgaaatt gcaaaaaaat taggattaaa aacagtcctg
    30961 accttagaaa aatatagata atggatatta aattaaaaga ttttgaagga cccctggact
    31021 tactcttgca tctggtttct aagtaccaga tggatatcta cgatgtgccc attacggaag
    31081 tcatcgaaca gtatctagcc tatgtctcaa ccctgcaggc catgcgtctg gaagtgacgg
    31141 gtgagtacat ggtcatggct agtcagctca tgctgattaa gagtcgtaaa ctccttccga
    31201 aggtagcaga agtgacagac ttgggagatg acctggagca ggacctcctc tctcaaatcg
    31261 aagaatatcg caagttcaag ctcttgggtg agcacttgga agccaagcac caagaacggg
    31321 cccagtatta ttccaaagcg ccgacagagt tgatttacga agatgcggag cttgtgcatg
    31381 acaagacgac cattgacctc tttttggctt tttcaaatat cctagccaag aaaaaagagg
    31441 agtttgcaca aaatcacacg actatcttgc gggatgagta taagattgag gacatgatga
    31501 ttattgtgaa agaatccttg attggacgag atcaattgcg cttgcaggat ttgttcaagg
    31561 aagcccagaa tgtccaagag gtcatcaccc tctttttggc aaccctagag ttaatcaaaa
    31621 cccaggagct gatcctcgtg caagaggaga gttttggaga tatctatctc atggaaaaga
    31681 aggaagaaag tcaagtgcct caaagctaga cttgatagag aggaaagatg agtactttag
    31741 caaaaataga agcgctcttg tttgtagcgg gtgaagatgg gattcgggtc cgccagttag
    31801 ctgaactcct ctctctgcca ccgacaggca tccagcaaag tttaggaaaa ttagcccaga
    31861 agtatgaaaa ggacccagat tccagtttgg ctttgattga gacaagtggt gcttatagat
    31921 tggtgaccaa gcctcaattt gcagagattt tgaaggaata ctctaaggcg cctatcaacc
    31981 agagcttgtc tcgggctgcc cttgagacct tgtccattat tgcctacaaa cagccgatta
    32041 cgcggataga aattgatgcc atccgtgggg ttaactcgag tggagccttg gcaaagttgc
    32101 aagcttttga cctgataaag gaagacggga aaaaggaagt attggggcgc cccaacctct
    32161 atgtgactac ggattatttc ctagattaca tggggataaa ccatttagaa gaattaccag
    32221 tgattgatga gcttgagatt caagcccaag aaagccaatt atttggtgaa aggatagaag
    32281 aagatgagaa tcaataagta tattgcccac gcaggtgtgg ccagtaggag aaaagcagaa
    32341 gagctgatca agcaaggttt ggtgacggtt aacggccaag tggtgcgtga actagcaacc
    32401 actatcaagt caggcgacaa ggtcgaagtt gaaggtcaac ctatctacaa cgaagaaaag
    32461 gtctattatc tgcttaacaa accacgcggt gtcatttcca gtgtaacaga tgacaagggt
    32521 cgcaagacgg ttgtcgacct cttgcccaat gtcaaagaac gtatttaccc tgtgggtcgt
    32581 ttggactggg atacatcggg tgtcttgatt ttgaccaatg atggggactt tacagacgag
    32641 atgattcacc ctcgtaatga gattgacaag gtttatgtcg cgcgtgttaa aggtgtggcc
    32701 aataaggaca atctccgccc cttgacccgt ggtcttgaga ttgatggtaa gaaaaccaag
    32761 ccagctgttt atgaaattct caaagtggac ccagtcaaaa atcgctctgt ggtgcagttg
    32821 accatccatg aagggcgtaa ccatcaggtt aaaaagatgt ttgaagctgt tggtctccaa
    32881 gtagataagt tgtctcggac tcgtttcgga cacctagact tgacaggact ccatccagga
    32941 gaatcccgtc gtcttaataa aaaagaaatc agccaactac acaccatggc tgtaactaag
    33001 aaataatgaa acgaatttta atagcgcctg tgcgctttta ccaacgtttt atctcaccag
    33061 tctttccacc ctcttgtcgc tttgagctga cttgttccaa ctacatgatt caggctattg
    33121 aaaaacatgg ttttaagggg gtattgatgg gcttggctcg gattttacgt tgtcatccct
    33181 ggtcgaaaac aggtaaggac cccgttccag accacttttc ccttaaacga aatcaagaag
    33241 gggaatgagg tggggtaaat agatttcaaa atgataaaaa cgcatcctat caggtttgag
    33301 taaacttgat aggatgcgtt ttagaatgtc aaaattttat actcttcgaa aatctcttca
    33361 aaccgcttca gctttcatct gcaacctcaa aacagtgttt tgagcaacct gcggctagtt
    33421 tcctagtttg ctctttgatt ttcattgagt attaaattga gtttgaagtg gcttatttca
    33481 aagctttttg tatgtcttca atcatgagtt ttgttgattc aagtccgcct ccgcttagat
    33541 accagaggtc tggtgttagt tggataatct taccattttt agcagcaggt gtttcagcga
    33601 taagggcatt ttctaggaca ccgtcgttgc tagagttgtc cccaccgatg gcaagggtac
    33661 ggttgatgac aaagaggatg tcagggttga tttctttgac actttcaaag ctgacttctt
    33721 gtccgtggcg tgagtcttca aattttgtat cagttggttt gaatttcaag gtttggtaca
    33781 agaaagagaa acgagatttg gcaccaaagg ctgccatttt tccttcatta aggaggatcg
    33841 caagggcttt tttgtcagag ctttcatttt tagtagcgac ttcttggatg ctcttgtcta
    33901 gcttggccaa ttcttccttg gctttctgtg taccagtttc gccgaaggca cttgctaagg
    33961 attcgatatt agccttggta gaagtccagt agtcgtcctt gcttgcttgg aagagaacgg
    34021 ttggggcgat ttctttgaat ttgtctacga atttttgtgt acgtggtgaa gcgataatca
    34081 aatcaggctc aagggcggcg atagcttcta aatcaggttc tttcatagaa ccaacatttt
    34141 tgacagttcc cactaggtct tttagataag tcggaacagt ttttgtaggc attccgacga
    34201 tatttttttc aaatcctaaa gcgcgaatag tatccgcaac gccgaggtca aaggtcacaa
    34261 tcttttcagg aactttggaa agtttgacct cgtccagtga acttttaatg gttacctctg
    34321 ttggagcaga gctactggtc tctgtctgac tagtgcttga gtttgtacta catgcaccaa
    34381 gtaggagcaa gaagctggcc actagggcag tgaaataaag tttaagggat gttttcataa
    34441 tttctccttt ttaaaatgtg ataacgattt agggagtctc ttgatcttat tgactaagag
    34501 actgaaggtt ctctaacttg agcttttatg ttactagcta tagatacaga tctttttgtc
    34561 attgatatca gctagcgtga tgggaatctc ataaagttga ctgagtaggt cagcctgcat
    34621 gatttgatcg gttcttccct tgctaaagac ctggccgtcc ttgaaggcga caatttcatc
    34681 tgcatactga ctggccatgt tgatatcgtg gaggacgatg ataatggtct tgccgagttc
    34741 ctccaccagt cgtcgaagaa tctgcatcat gctgacgctt tgcttgatat cgagattgtt
    34801 gagtggttcg tccagcaaga taaagtccgt atcctgggcc agtaccatag cgataaagac
    34861 gcgctggagt tgcccccctg acaggctatt gatgtagcgg tcttttaagt tggtcagttc
    34921 caaatagttc agagtttctc ggattttttc ccagtcttct gatctaagtc gacctcggct
    34981 gtagggaaaa cgtccaaaac tgaccagttc ttcaacagtc aatttggctt ggtaattgat
    35041 tttctgtttt aggatggtta gttcttgggc cagttcttgc gaattccagc tctcgatttc
    35101 acgtcctttg atactgagaa ctccctgatc tttcttggtt agtctgctca tgatggagag
    35161 gagagtcgat tttccagcac catttggacc aataaaggct gtcagttttt gaggactgac
    35221 ttcaagcgaa atgccttgca aaatatcctg tttttgaatg gatttgtcaa tgttttccag
    35281 tttcactgac gagacctcct atatagtaag ataaagaata agaagccacc cacactctca
    35341 atgatcatac tgatacgaat ttccagtgca aagactcgtt caatcaaggc ttgccccaag
    35401 gttaagctaa taaatccaat cagaatggcc actataaaga gtaacttgtg ctgatagtct
    35461 ttgacaatca ggtaggtgag gttggccagc ataaagccga agaaggccat aggtcctacc
    35521 aaggcagtgg ccgttgaggt caaaagcacg attccccaga ggagctcttt ctgttctttt
    35581 tcaacatcga gtcccaatat ctgagccgtt tctctttgca ggtgcaagac atctagaacg
    35641 actgcttttc gaaagaaaaa gattgtcaaa gcgaggatga tcagagaacc gatggctagg
    35701 atggaagtgt tgagatgttg aaaggaggca aaaagactat tttgcagttt atcgtattcg
    35761 tttggatcca ttaggacttg aaggaaggtg ctgatatttc gaaagagact tctgagcgct
    35821 agacagatca gcaggatgaa gaccaggtct tgcttcatca gtgtcttcaa gtaaccttgt
    35881 aaggcgagaa agaagaggga ctggacaaga agtaagacta ggaattctaa gataggggat
    35941 ttgccaagtt gaagaaactt gctttcaaaa accagtagta gggtttgtag taggacgtag
    36001 aaggattcaa ttcccaaaat actaggcgtc aggaagcgat tttccgtcag ggtttgaaaa
    36061 ctaatggtcg aaatcccagt cgcgatggct accaagagat aaacgatgat cttttgggaa
    36121 cgcaacttcc aagcaaaggc tgacaagtga gtgatgggcc aaaagtagag aagacaagct
    36181 ccgatggcaa gaataatgag aatccagaag agcttggtat gtttgctttt agtctgcatc
    36241 ttttcgtccc cctctccaga gaagtaggat aaagacgaga ctaccgatga ttcctagcaa
    36301 gagactgaca gacaactcat agggcctaat cagaactcgg gataggatat cgcaagccag
    36361 aactagattg gcaccaacca gtgcgaccat gagtttggtt tgacttagat tatctccata
    36421 gcacttgcga acaagattgg gaacgataac tccgagaaat ggtaggccac ccacggtaat
    36481 catggtgacg cttgtcgtta gcgccaccag aaagagggcc agtttttcaa gtagggagta
    36541 ggaaatcccc aaactctcgc tggtttcttt ccctagattc atgatggtga aggtttggga
    36601 taatttccaa acggttatca ggatgatgag gcctaagaag agccactcat actgatgggt
    36661 ctgaatcatg gagaaggagc cctgggtcca ggcagtcata ctctgaacca gattgaaacg
    36721 ataggcgata acttctgtga ctgagccgat aatcccgcta tagatgatcc caatcagagg
    36781 caacatccac ctttccttta cagtaaaaat ggtcataaag gctaggaaga agagggtgaa
    36841 tacgatggat gaaacaaaag cgaagagcat cttttgggtc agactagccg atggaaagac
    36901 aaaaaggctc agcaccattc ccagtttggc ggcttcagtc gttccaactg tactcggtgc
    36961 agcaaactga ttttgggtaa tagtctgcat gagaaggcct gccatactca tactagaggc
    37021 agtcaggaga atactgatag ttcttgggag acgggactct tgaaagagga gccaggtctg
    37081 ctggtcgaaa tcaaatagct ttccccatga aaaatcactg gtcccaatgc taatagagag
    37141 aaagactagg agtagaagta agccaattaa ataatgagaa agtttcatac cccgtccttt
    37201 catgtagatt tggtatcgaa agatatctgc ggatataaat gtaacattat ttttctaatc
    37261 tgtcaataaa atttctgaca atttaataaa tacaacaagg agagagcaac aagactttct
    37321 cctttgttat cctattctaa aatgttttta ccttaatctg ataaaataat atcttcgagg
    37381 gagtagctag ccgtccaatc aagatattgt ttagcttttg aagcatctgc taggacactg
    37441 gctgggtcac tagcacgtcg agcaacaatc tcgtgtggga ttttttaatt tagtaattct
    37501 tcagcagttt taaagatttc tttgatagta tagccttttt tagttcctaa gttaaagatt
    37561 tgagaagaac tgtcttcttg aaataggtag ttcattcctt taacatgagc ctatgcaagg
    37621 tccaagacat aaatgtaatc tcgaatacat gaaccgtcac gtgtatcgta gtcatctcca
    37681 aatattttta agctatcatt ttgtcccaat gcggtcttgt tgatatttgg aatgatgtga
    37741 gttggatttt tcacacgcag accgtttgaa gcatccattt cagccccagc aacattaaag
    37801 taacggaaaa taacatattt ccagtcgtag cgattggcca tccagtaaat cattcgttcg
    37861 cccatcagtt ttgtctctgt ataagggttg acagggtcga tcagggtatc ttcagtcgcc
    37921 ggcttgtcaa tacagttatt tccatagaga gaagcagtcg aagagaacat gattttttga
    37981 gtgccaactt cagataagac tttgagaact tggttcctac cagcaacgtt ggcagtgaag
    38041 tatttacttg gattttcaat actttcgctc acaacaattt cacctgcata atggaggaca
    38101 gcatcaatct gattttcttc taagtaagcc tttaaggcgc tagcatcata aacatccagt
    38161 tctttaaagc tagcacgatt atccacagtc gctcgatttc ctgtggagag attatcgagg
    38221 acatgcacct tataaccagc atttaaaaga gctttaacgg tatgggagcc aatgtagcta
    38281 gtcccacctg taacaagaat tgttttggtc atgatttttt ccttttctag ttttgtacta
    38341 tagtaaattg aaataagata tgaacaactc tattaggaaa ggcaaattaa ttcctagaaa
    38401 tgttttagca gctacagcgt actattccaa actcaaccaa ctatatattt aaagaaagaa
    38461 gaaagggaag tcaactattt tctgtaaatt tcatgaaaaa tccaaacaac tttgatggtg
    38521 tattgttttt ttgtttggaa ataaatattc gagttaattt tggaatgttt actagatttt
    38581 gcactacatg caagagaata ctatcctttt ctaagataga gcaggactaa gatactaact
    38641 tagaaatcca ccttcccact atccttctcc tataaaaagt ggtaaaatgg atgaaagaaa
    38701 gaaggaactg aaatgacaac attattttca aaaattaaag aagtaacaga acttgctgca
    38761 gtctcaggtc atgaagcgcc tgtccgtgct tatcttcgtg aaaagttgac accgcatgtg
    38821 gatgaagtgg tgacagatgg cttgggtggt atttttggta tcaaacattc agaagctgtg
    38881 gatgcaccgc gcgtcttggt cgcttctcat atggacgaag ttggttttat ggtcagcgaa
    38941 atcaagccag atggtacctt ccgtgtcgta gaaatcggtg gctggaaccc catggtggtt
    39001 agcagccaac gtttcaaact cttgactcgt gatggtcatg aaattcctgt gatttcaggt
    39061 tctgttcctc cgcatttgac tcgtggaaag gggggaccaa ccatgccagc cattgccgat
    39121 atcgtttttg atggtggttt tgcggacaag gctgaggcag aaagttttgg catccgtcct
    39181 ggtgatacca tcgtaccaga tagttctgca attttgacag ccaatgaaaa aaatatcatc
    39241 tcaaaagctt gggataaccg ctacggtgtc ctcatggtaa gcgagctagc tgaagcttta
    39301 tcaggtcaaa aactcggcaa tgaactctat ctgggttcta acgtccaaga agaagttggt
    39361 ctgcgtggcg ctcatacctc tacaaccaag tttgacccag aagtcttcct cgcagttgat
    39421 tgctcaccag caggtgatgt ctacggtggt caaggcaaga ttggagatgg aaccttgatt
    39481 cgtttctatg atccaggtca cttgcttctc ccagggatga aggatttcct tttgacaacg
    39541 gctgaagaag ctggtatcaa gtaccaatac tactgtggta aaggcggaac agatgcaggt
    39601 gcagctcatc tgaaaaatgg tggtgtccca tcaacaacta tcggtgtctg cgctcgttat
    39661 atccattctc accaaaccct ctatgcaatg gatgacttcc tagaagcgca agctttctta
    39721 caatccttgg tgaagaaatt ggatcgttca acggttgatt tgattaaaca ttattaaacc
    39781 ataagggagg tggtagggat ggcagaacca aacctagaaa gccttataaa agatctttac
    39841 aatcatgctc gacatgattt gagtgaagat ttagttgctg ctctcctaga gactactaaa
    39901 aaactgccta ctacaaatga gcaattgcag gcagttcgtc tctcaggcct ggtcaatcgt
    39961 gaattgctcc taaatcccaa acatccagca cctgagttgc tcaacttggc tcgctttatc
    40021 aaaagagaag aagccaagta cagaggaact gcgacttctg cacttatgta tgaggaactt
    40081 tttaaaatgc tttgattcca ttgtggatca aagcattttt tataagacct atctcgtgag
    40141 cgttcaaata gtagtaacaa ggaatcatga gaagtcagcc gagaccatag tagtgaagaa
    40201 acttctgtaa tggaagtgga gtgaagtgag gaatcgtcaa acggtagggg ataggctgtt
    40261 tgaagggtgc tacgaaaaag atagggtaag gtgaaattat agcggaatga aataagatat
    40321 gaacaaattg attagggaaa tcaaatgaat ttatagaaat cttttagcag tcatggtgtc
    40381 ctattccagt ttcgaaatgc tataaagacg aacaaattga ttgggaaatt caaatcgctt
    40441 tctatcaatg ttttagaaga tacagtgccc tagtccaact tcaatatact ataaaagaac
    40501 agatggaagc aattatgatt tacttctatc tttaaaataa atgctctgat aggaaaaatg
    40561 tgtcccctca taaaatatag gatagtacgg atggaaggct tttgtagact ggaggacgaa
    40621 ggagtttaga aactctcgtt aaaagttagt tgagccggag tatggtggtg tggataatta
    40681 tcaaaaatta tttctaaatc gaaatagttg acagttagaa cgatgagtgt tacaattgtt
    40741 ttattcattt cgatatcgaa ataaattgga ggtgttatga aagatggtca tttgctagcc
    40801 catcatattc gtttgttgaa tgggcggatt tttcaaaagt tactgagtca agatcctgag
    40861 gctctttata ggggtgaaca gggcaagatt ttagcggttt tatggaatag tgaaactggc
    40921 tgcgcaactg cgacagatat cgcgcttgcg actggacttg cgaataatac gctgacgact
    40981 atgataaaaa agctagagga acaaaagctt gtaattgtta gtccgtgtgg aaaagacaag
    41041 cgtaagaagt atttagtttt aacggagtta ggcaagtccc agaaagaagt ggggcatcgt
    41101 gtcagtcaga aattggatac tatcttttac aaaggatttt cagaggaaga aattcaccaa
    41161 tttgaaggtt ttcaagaaag aattttggcg aatctgaaag agaagggaaa tgaggtttag
    41221 aatatgtcac aacaagtgaa aaatgctcac aacctataca tccatgccat tcaagacgga
    41281 cgagttgctg aggctcaagc ccagtctgta ggggatacct atatccaaca ttcgacaggt
    41341 gttcctgacg ggaaagaagg atttgcagcc ttctttgcag atttctttga gcgtcatcca
    41401 gagcgtcaga ttaagattgt ccgcaccatt gaggatggca atctggtctt tgttcatgtt
    41461 catcaatatc tgaatggtgg agaagctcaa tgggtgacga cggatacttt ccgtgaggat
    41521 gagaatggtt gtattgttga gcattgggat gtcattgact actatcgaac acctgaaaat
    41581 gaccaactag atcaaatttt tggagatttt gaaatcaagg atttggataa gaaagcagaa
    41641 aataaaaagc tggttcgccg tttcttgaca gaaattttcc aaaatgggga gctagagcag
    41701 tggagtgatt atgtggcaga cgatttgatt cagcataatc atgagattgg acaaggaagt
    41761 gctgcttata aaaactatgt ggctgaatat agtgtcactt ttgactttgt tttccaactc
    41821 ttaggacaag gaaactatgt ggttagctat ggtcagactc agattgatgg cgttgcttat
    41881 gcccagtacg atatcttccg tttagagaac gggaaaattg tggagcattg ggataataag
    41941 gaagtcatgc ctaaggtaga agacttgact aatcgaggga agttttaaat tgaggacaaa
    42001 gaatgattga atacaaaaat gtagcactgc gctacacaga aaaggatgtc ttgagagatg
    42061 tcaacttaca gattgaggat ggggaattta tggttttagt agggccttct gggtcaggta
    42121 agacgaccat gctcaagatg attaaccgtc ttttggaacc aactgatgga aatatttata
    42181 tggatgggaa gcgcatcaaa gactatgatg agcgtgaact tcgtctttct actggttatg
    42241 ttttacaggc tattgctctt tttccaaatc taacagttgc ggaaaatatt gctctcattc
    42301 ctgaaatgaa ggggtggagc aaggaagaaa ttacgaagaa aacagaagag cttttggcta
    42361 aggttggttt accagtagcc gagtatgggc atcgcttacc tagtgaatta tctggtggag
    42421 aacagcaacg ggtcggtatt gtccgagcta tgattggtca gcccaagatt ttcctcatgg
    42481 atgaaccctt ttcggccttg gatgctattt cgagaaaaca gttgcaggtt ctgacaaaag
    42541 aattgcataa agagtttggg atgacaacga tttttgtaac ccatgatacg gatgaagcct
    42601 tgaagttggc ggaccgtatt gctgtcttgc aggatggaga aattcgccag gtagcgaatc
    42661 ccgagacaat tttaaaagcg cctgcaacag actttgtagc agacttgttt ggaggtagtg
    42721 ttcatgacta atttaattgc aacttttcag gatcgtttta gtgattggtt gacagctcta
    42781 tctcaacatt tgcagttgtc acttttgacc ttgttactag ctattttgct tgcgattccc
    42841 ttggctgttt ttcttcgcta tcatgagaag ttggcggatt gggtcttaca gattgcaggg
    42901 attttccaga ccatcccgtc tctggccttg ttgggactct ttattccctt gatgggaatt
    42961 gggactttac cggcattgac agctctagtg atttatgcga ttttccctat tttgcaaaat
    43021 actatcactg ggctgaaggg aattgatccg aacctgcaag aggctgggat tgcctttggg
    43081 atgaccagat gggaacgtct caagaaattt gaaattccac ttgccatgcc tgttatcatg
    43141 tctgggattc ggacggcagc tgttttgatt atcggtacgg caaccttggc ggccttgatt
    43201 ggagcagggg gactgggttc ctttatcctg ttgggaattg accgtaataa tgccagtttg
    43261 attttgattg gggcactttc ttctgcagtg cttgctattg cctttaactt cctactaaaa
    43321 gtaatggaaa aagcaaaatt acggacgatt ttctcaggtt ttgccttggt ggctttatta
    43381 ctgggtctgt cttatagtcc agcccttttg gctcaaaaag agaaggaaaa cttgattatt
    43441 gctgggaaaa taggcccaga accagaaatt ttggctaata tgtataaatt gctgattgaa
    43501 gaaaatacca gcatgactgc gactgttaaa ccgaattttg ggacgacaag tttcctttat
    43561 gaagctctga aaaaaggtga tattgacatt tatcctgaat ttaccggtac ggtgactgaa
    43621 agtttgcttc aaccatcacc caaggtgagt catgagccag agcaggttta tcaagtggcg
    43681 cgtgatggca ttgccaagca ggatcatcta gcctatctca aacctatgtc ttatcaaaat
    43741 acctatgctg tagctgttcc gaaaaagatt gctcaagaat atggcttgaa gaccatttcg
    43801 gatttgaaaa aagtggaagg gcagctgaag gcaggcttta cgcttgagtt taacgaccgt
    43861 gaagatggaa ataagggctt gcaatcaatg tatggtctca atctcaatgt ggcgactatg
    43921 cagccagctc ttcgttatca ggcaattcag tcaggggata ttcaaatcac ggatgcctat
    43981 tcgactgatg cggaattgga gcgttatgat ttacaggtct tggaagatga caagcaactc
    44041 ttcccacctt atcaaggggc tccactcatg aaagaagctc ttctcaagaa acacccagag
    44101 ttggaaagag ttcttaatac attggctggt aagattacag aaagccagat gagccagctc
    44161 aactaccaag tcggtgttga aggcaagtca gcaaagcaag tagccaagga gtttctccaa
    44221 gaacaaggtt tgttgaagaa atgatgggac agagacttta aacatactga actcaacttc
    44281 cttaaacgac tagataaaag aatgctcaga caatttcgtc tgggcttttt tgatgtgaga
    44341 atgactgaat gtcacttaaa atggaaagaa agagaaaatt ttcatgattt tctaaaattt
    44401 tactgtaaag acagttgact attcataaaa taggtgtata atattttgtg aactacttaa
    44461 caaataagaa gtttcagctc atgtcgacta aggttagaaa tcttgtgtat aggcagttca
    44521 ttatctaata gagcgttgcg tccgaaagtc tatccagaca cggctcttta aaaacaaaag
    44581 gagaaatgat gcatacttat ttgcaaaaga aaattgaaaa tatcaaaaca accctaggtg
    44641 aaatgtcagg tggttaccgt cgtatggttg cggctatggc tgatttagga ttttcaggaa
    44701 ctatgaaggc tatctgggat gacctctttg cccatcgtag ttttgcccag tggatttatt
    44761 tgctggtttt aggaagtttt cctctctggc tggagttggt ttacgaacat cgtattgttg
    44821 actggattgg gatgatttgt agcttgacag ggattatctg tgtaatcttt gtatcggaag
    44881 gtcgagcaag taattatctt tttggcttga ttaactctgt tatttacctt attttggccc
    44941 tacagaaagg cttttatggt gaggtgctga cgacacttta cttcacagtc atgcagccaa
    45001 ttggacttct agtttggatt tatcaggcac agtttaagaa ggaaaagcag gagtttgtcg
    45061 cgcgtaaact ggacggcaag ggctggacaa agtatctttc cattagtgtg ctttggtggt
    45121 tggcctttgg cttcatttat cagtctattg gtgccaatcg tccctatcgt gattcaatca
    45181 cagatgcaac caatggggta gggcaaatcc tcatgacagc tgtttaccgt gaacagtgga
    45241 tattctgggc ggctaccaat gtcttttcaa tctatctctg gtggggagaa agcctgcaaa
    45301 ttcaagggaa atatctaatt tatctcatta acagtctagt tggttggtat caatggagca
    45361 aggcagctaa gcagaatact gatttactta actaggaaaa gatgtttgaa agtgctgttt
    45421 tgagatttcg attaaaacag atatagttga taatcaagga tttatagtat gaaaaagagg
    45481 atcggcgggt cctcttttgt tgttgaaaag ataaaaaact cagtaatcta gaaataagac
    45541 aactgagctt tactctatat tcaattttta ggaatgagaa ggtctagata aaattggaca
    45601 acttcctggt ctgtgaaatc ttgacctttt ttgagccacc aggtcaatgt ctcgataaag
    45661 ttggacatga ccaagtgttg gaggtaagaa gtaggcagat tagggtgggc ttcttttaaa
    45721 ttatcagcta gcacggaata gacgtggtgc tcaagctctc tctggagttg acggaggaag
    45781 tagtcatttt tggaaaatag cagactggtg atatggtctt ggtttttatg aaaatggaga
    45841 aagaggtggg cgaggtagtc ctcggttgaa atggcttgct ctctttcaaa aagatgatgg
    45901 aagaggtagc ggcagagctg gtccagaaga agctccttac tttcatagtg acagtaaaag
    45961 gtggatcttc ccacatctgc gagatcaatg atatcctgaa cagtagtggc ctcgtagccc
    46021 ttagcattca aaagttgtat aaaagcttga tagatggctt ttttggtttt gctgatacgg
    46081 cggtcaatgt tagtcatatg gacacttaag gcaaattgtt cagaactgaa taaagctgac
    46141 gttttgcttc tatcctttct ttgagtttta gtggataatg ataatgaaca aggtgttcat
    46201 aaatctatta taacaaagga atgagaaata tgaaggcaaa atatgctgtt tgggtggctt
    46261 ttttcttaaa tttgacttat gccattgttg agtttattgc aggtggagta tttggttcta
    46321 gcgctgttct tgctgactct gtgcatgact tgggagatgc gattgcaatt ggaatatcag
    46381 cttttctaga aacaatctcc aatcgtgaag aagacaatca gtacaccttg ggctataagc
    46441 ggtttagcct gctaggagcc ttggtaacag ctgtgattct cgtaacgggc tctgttctag
    46501 tcattttgga aaatgtcacg aagattttgc atccgcaacc agtcaatgat gaggggattc
    46561 tctggttagg aattattgcg attactatca atctgttagc gagtctggtg gttggtaagg
    46621 gaaagacaaa gaatgagtct attctgagtt tgcattttct ggaagatacg ctagggtggg
    46681 tagctgttat cctgatggcg attgttcttc gatttacgga ctggtatatc ctagatcctc
    46741 ttttgtccct tgtcatttct ttctttattc tttcaaaagc ccttccacgt ttttggtcta
    46801 cactcaagat tttcttggat gctgtgccag aaggtcttga tatcaagcaa gtaaagagtg
    46861 gcctggagcg attggacaat gtggccagcc ttaatcagct taatctctgg actatggatg
    46921 ctttggaaaa aaatgccatt gtacatgttt gtctaaaaga aatggaacat atggaaactt
    46981 gtaaagagtc tattcgaatt ttcctaaaag attgtggttt tcaaaatatt accattgaaa
    47041 ttgatgctga cctagaaact caccaaaccc ataagcgaaa ggtgtgtgac ttggaacgga
    47101 gttatgagca tcaacattag aaaaaagtga aaaatacttg ggtactatct tatttggaat
    47161 agagtaattt ctttattatt taaatatttc aaaaattggt aagagaagag cattgtataa
    47221 actccagata tatgattgtt aatgataaaa atttttcgat tagatacaaa atgcttgact
    47281 tggagtcaac tcaaagttat ataataagat aagtgagtta gaatagcgtg aattcagtga
    47341 atgaaatgag aggaggttag cgtgtgaata ttaaatctgc cagtgatttg ttgggaattt
    47401 cagcggatac gattcggtat tatgaacggg ttggtcttgt gccaccgatt actcgtactg
    47461 ctactgggat tcgtgatttt caagatcagg atatcgaagc gctggaattt attaagtgtt
    47521 ttcgttcggc gggtgtctct gtagatagtt tagttgacta tatgtcgctc taccaaaagg
    47581 gagatgaaac gagagaggag aggcttggta ttttagaaga ggaaaagcaa aaattagagg
    47641 agcgcttgtc tcagctacag acagctttaa atcgtttaaa tctcaaaatt aaactttata
    47701 aggaaggaaa attttaaatg aaatcagcag tatatacaaa ggcaggtcag gttggacttg
    47761 ctagcattga acgtccgcaa ataatagaag cggatgatgt gattattcgt gtggttcgtg
    47821 cgtgcgtttg tggttcagat ttatggaggt accgtaatcc agaaacgaaa gctggacata
    47881 aaaatagtgg acacgaagcg attgggattg ttgaagaagc tggggaagcc attacgacgg
    47941 tgaaaccagg tgattttgtg attgtccctt ttacacatgg atgtggtgag tgtgatgcct
    48001 gtcttgctgg atttgacggt tcttgcgaca atcatattgg caataatttg gggggtgatt
    48061 ttcaggcaga atatattcgc ttccactatg caaactgggc gctggttaaa atccctggtc
    48121 aaccttctga ttatacagaa gggatgctca agtccctttt gactcttgca gatgtcatgc
    48181 cgacaggcta tcatgcagcg cgtgttgcaa atgttcaaaa aggggataag gttgttgtta
    48241 taggtgatgg ggctgttggt caatgtgctg tcatcgcggc taagatgcgt ggagcatcac
    48301 aaattatcct tatgagccgt catgaagacc gtcaaaagat ggctatggag tcaggtgcga
    48361 cagctgttgt tgcagaacgt ggtcaagaag gaattaccaa ggtgcgtgaa atcctcggtg
    48421 gaggagcaga cgcagcactt gaatgtgttg gtacggaggc tgctatagaa caggcgctag
    48481 gtgttcttca taatggaggg cgtatgggct ttgtaggagt cccacactat aataatcgtg
    48541 ctcttggttc gacatttatg caaaatatct ctgtagcagg tggggcagct tctgctacaa
    48601 catacgataa gcaattttta ctaaaagtcg tccttgatgg tgatatcaat ccaggtcgcg
    48661 tctttacttc aagttataaa ctggaagata tcgaccaagc ctacaaagat atggatgaac
    48721 gtaagacaat taagtctatg attgtaatcg aataaaaaac gaataggagt tttagaactc
    48781 tattcgtttt ttatgttatc ctattcttga tttagggtac tttctcttaa tgtcagtctg
    48841 gttcccagca tggtcaggct agggattttc cgaccgtgga ggacttcctt gttaagaata
    48901 tccatacctg ctcggcccat ttcttcagta taaactgtaa tactagagag gggaggatag
    48961 acctgtttgg tcagactggt gtcgttgaat gaaatgaggc tgacgcgatc tggcaggctg
    49021 attccagctt cttggagggc acggagggca ccgatagcta aactatcgct ggctgcgaaa
    49081 aatgctggcg gaagttggtc tcccaagctc tgaatggcct ccttcattaa gtcatagcca
    49141 gactgggcag taaatcttcc ttgaaagacc agttcatcat gatagattcc cctcgcttga
    49201 ctgtagtttc taaaattttc cagccgctta tcctcaatga tttcttcttg gtctgttgtt
    49261 tcttcaaggc ctgttagaat cccgatacgg tccattcctt ggctgaggaa ataatcgaca
    49321 acctgtttca tagcagtgta aaaatccgtg ataatacagg tatgtcccag ggaaagtgta
    49381 tcgctgtcta gaaatacaag aggcttttgg tattcttcaa aggcagaaat ctgagctcga
    49441 ctaaactttc cgatgcagag aatcccaatc acttcctcgc ttagggtaaa agggtggtca
    49501 ttaaaatagc gcaagatatc gtagtccaac tcttgggctc ttttttctat tcctaggcga
    49561 atctggtagt agtagaggtc gtctagctcc ccttgttcgc tgacccattg aataatggca
    49621 atcttttgct tgggtttatg ggactcgcct gtcttgaggt gcttggtgta gcccagctct
    49681 tcagcaacgg ttaaaatacg gtgtctggtt tcttctgtaa cagataggct ctggtcgcgg
    49741 ttgagaacac gggatacggt cgcgatagag acagaggcta gctgtgcaat gtcttttaag
    49801 gtagccataa atcctccttg attaggttag tatatcatat ttttctgctt tttactgata
    49861 ttttagtaaa attttagtaa aaaggattga ccttgggaaa tcccttggat acaatagaag
    49921 aaaacgatta cacgttaagg tggcttaacg gacagtcaaa ggagaaatca tatgacacaa
    49981 catcttactg ctgaaactct tcgcaaagac tttcttgctg tttttggtca agaagcagac
    50041 caaaccttct tttcaccagg tcgtatcaat ttgattggtg aacacacaga ctacaacggt
    50101 gggcacgttt ttccagctgc tatttccttg ggaacttatg gtgcagctcg caagcgtgaa
    50161 gaccaagttt tacgtttcta ctcagctaac tttgaggaca agggcattat cgaagtgcct
    50221 ctcgctgacc tcaagtttga aaaagagcac aactggacca attatccaaa aggtgtcctt
    50281 catttcttgc aagaagctgg gcacgtgatt gacaaaggtt ttgattttta tgtttatggg
    50341 aatataccaa atggtgctgg tttgtcttct tcagcatcct tggagctctt gacaggagtc
    50401 gtggcagagc atctctttga tttaaaatta gagcgtctcg atttggttaa aatcggaaaa
    50461 caaacagaaa acaactttat cggagtcaac tctggtatca tggaccagtt tgctattggt
    50521 atgggggctg atcaacgtgc tatttacctt gataccaaca ccttagagta tgatttggtg
    50581 ccacttgatt tgaaggacaa tgtcgttgtt atcatgaaca ccaacaaacg ccgtgaattg
    50641 gcggactcta aatacaatga acgtcgtgct gagtgtgaaa aagcagtgga agaattgcaa
    50701 gttgccttgt atattcagac cctgggtgaa ttggacgagt gggccgttga ccaatatagc
    50761 tatttgatta aagatgaaaa tcgtttgaaa cgtgctcgcc atgctgtgct tgaaaaccaa
    50821 cgtaccctta aagctcaagc agcccttcaa gcaggtgatt tggaaacatt tggtcgtttg
    50881 atgaatgcgt cacacgtttc tctggagcat gattatgaag taactggttt ggaattagat
    50941 acccttgttc acacagcttg ggcacaagaa ggagttctcg gtgctcgtat gacaggggct
    51001 ggttttggtg gctgtgccat tgccttggtt caaaaagata ctgttgaggc ctttaaggaa
    51061 gctgtaggca aacactacga ggaagtagtt ggatacgctc caagcttcta tatcgctgaa
    51121 gttgcaggtg gcactcgcgt ccttgactag tcaaaaggag gctctatagt gaccttagta
    51181 gataaatttg taacacatgt catttctgaa agttcatttg aggaaatgga tcgaatctac
    51241 ctgaccaatc gtgttttggc acgagtggga gaaggtgttt tggaagttga gaccaatctg
    51301 gataaattga ttgacctcaa ggaccagcta gttgaggaag ccgttcgatt agagacgatt
    51361 gaggatagtc agactgcgcg tgaaatcctt ggtactgaat tgatggactt ggtgactcct
    51421 tgtccgagtc aggtcaatcg tgacttctgg gaagcctatg cctactctcc tgagcaagcg
    51481 atagaggatt tttatcaact cagtcagaaa aatgactaca tcaaactcaa ggccattgct
    51541 aaaaatatcg cttatcgtgt tccatctgat tatggagaac ttgaaattac catcaatctc
    51601 tctaagcctg aaaaggatcc gaaagagatt gcggcagcca agttggtgca agctagtaat
    51661 tatcctcagt gtcaactttg tttagagaat gagggttacc atggtcgggt caaccaccca
    51721 gctcgcacca accaccggat tatccgtttt gaaatggttg gtcaggaatg gggtttccag
    51781 tattcgccct atgcttactt taatgagcat tgtatctttt tagatggcca gcatcgtccc
    51841 atggccatta gtcgtcagag ttttgaacgt ctgttggcta tcgtagagca gtttccagga
    51901 tattttgctg gatctaatgc cgacctgccg attgtggggg gctctattct aactcatgat
    51961 cattatcagg gaggccgtca cgtatttcct atggaattgg ctcccttgca aaagaccttc
    52021 cgatttgctg gttttgagca ggtcaaggct ggaattatca agtggcccat gtctgtccta
    52081 cgcttgactt cggattccaa agaggatttg attaacttag ctgataagat tttccaggaa
    52141 tggcgtcagt attcagattc tagtgtgcag attttggcag agacagacgg gacaccgcat
    52201 cacaccatca caccaatagc gcgtaagcgt gatggacagt ttgagttgga cttggtcttg
    52261 cgagacaatc agacttcagc agagcatcct gatggcatct atcatcccca caaggatgtc
    52321 caacatatca agaaggaaaa tatcggcttg attgaggtca tgggcttggc aatcttgcca
    52381 ccacgtctga aagaagaagt ggagcaagtc gctagctatc ttgtaggaga aactgttaca
    52441 gttgccgatt atcatcagga gtgggcagac caactcaaat cccaacatcc agacctaacg
    52501 gataaagaaa aagcccttgc aatcgtcaag gactctgtgg gtgctatctt tgtgcgtgta
    52561 cttgaggatg caggagtcta caagcagaca gaacaagggc agacagcctt tatgcgcttt
    52621 gtggaacatg tcggaatttc actagactag gagctttctc cttgcacagt cctataaaaa
    52681 gtagtatcat agtgtcgttt gaaatatcag gaggaaacga tgaaagactt tcattttgac
    52741 gctatatctg cctttgaaaa ttacgaaatt gaaaaaatga gagatggtca cgttgtggtg
    52801 acgaccaaag tagtgaactc gtcgctcaac tactatggca atgcccacgg tggctatcta
    52861 ttcacgctat gtgaccaaat cagtggtttg gtggttatct cgctgggact tgatggggtg
    52921 acactccaat cctctatcaa ctaccttaag gcaggaaaac tcgacgatgt attgaccatt
    52981 aaaggagaat gtgtccatca aggccgtaca acctgtgtga tggatgtgga tatcaccaat
    53041 caagagggca gaaatgtctg taaagcaacc tttaccatgt ttgtcacagg ccaaaggtct
    53101 gaggaaagac aggtaaggat ataaagaaag gtgagtggga taaatttatc tcactcattt
    53161 ttaatttatg agatatgtta gaaggaaata taaaagagag tgatgaaata caaatgtaat
    53221 aggtacatat atgtggtata ctagttatag tagattttaa ttgcttatat cgagtgagtt
    53281 ctcatattag tgaggaattt ttaaatggaa ttacacttta atttagaatt agtagaaacc
    53341 tataaaagta atagccaaaa ggcacgtatc ttaacggagg attgggttta tcgtcagtct
    53401 tattgcccta attgtgggaa caatccctta aatcattttg aaaataatcg gcctgtagca
    53461 gatttttact gtaatcattg tagtgaggag tttgaactaa agagcaaaaa aggaaatttt
    53521 tcatcaacaa tcaatgatgg tgcttatgca acgatgatga agcgtgtgca ggcagataat
    53581 aatcctaatt tcttttttta aacttacaca aaaaattttg aggtaaataa ctttcttgtc
    53641 cttccgaagc aatttgttac accgaaatcg attattcaaa gaaaaccact tgcaccaact
    53701 gctagacgag caggttggat tggttgtaac attgatttat cacaagtacc ttctaaagga
    53761 aggatatttc ttgtgcaaga tggacaagtt agagatccag aaaaagttac aaaagaattt
    53821 aagcaaggtt tatttttaag gaagagctct ctgtcatcaa gaggttggac aatagaaatt
    53881 ctaaattgta tagataagat agagggttca gaatttaccc ttgaagatat gtatcgtttt
    53941 gaaagtgacc taaaaaatat ctttgttaag aacaatcata tcaaagaaaa gattaggcaa
    54001 cagcttcaaa tattaagaga caaagaaata atagaattta aaggtagagg aaagtatcgg
    54061 aaattatgaa aacgaaacaa cttgttgcat cagaagaggt gtatgatttc ttaaaagtca
    54121 tctggcctga ttatgaaact gaaagccgtt acgataacct aagtttaatc gtctgtacct
    54181 tatcagatcc cgattgtgtg agatggttat ctgaaaatat gaaatttggt gacgaaaaac
    54241 aactagcttt gatgaaggaa aaatatgggt gggaagtagg agataaattg ccagagtggc
    54301 tacatagctc ctatcataga ttattgttaa taggtgaatt attggaaagc aatctaaaac
    54361 tgaaaaagta tacagtagaa attacagaaa ctttatcacg tttagtaagt atagaggctg
    54421 aaaatccaga tgaagccgaa cgacttgtaa gagaaaagta taagagttgt gaaattgttc
    54481 ttgatgcaga tgattttcag gactatgacg ctagcatata tgaataggta gatgttttta
    54541 ttttgtcaca caaaaaagag gctcgcacct ctttttctta tttcttttta tgatttaata
    54601 cggcattgag gacaatagcg agtaggctgg ctacgacgat tccttttgag aagaacattt
    54661 ggaaggctgt cggcatgctg acaaagagat tactgttgtt gagaccgaca cctgcagcga
    54721 ttgaaacagc tgcgataagg aagttgtgtt cattgttagc aaagtcaact cgggcgagga
    54781 tttgcatccc ttgaatagat acaaaaccaa acatcaccag catggcaccg ccgaggacgg
    54841 agcttggaat gatttgggca agggcaccaa acttaggaag cagtccaagg agaaccagga
    54901 aaccagctgc gtagtagatt ggcaggcgtt ttttgatgcc tgacaattta accaaaccaa
    54961 cgttttgtga aaatccggtg taagggaagg tgttaaagat tcctccgaga agtaccgcca
    55021 aaccttctgc gcggtaaccg ttgcgaaggc gcgtgctgtc gattggatct tttgtgatat
    55081 cagacaaggc tagataaaca ccagttgact caaccataga caccgttgcg ataatacaca
    55141 tcatgacaat agatgagatt tcaaaggttg gcatcccaaa gtagagtgga gttgggacat
    55201 ggacaagtgg agctaccgca acaggagaga agtccaccaa gcccatagta gcagcaatgg
    55261 cagttccaac aaccagacca atcaaaatag agatagactt gataaatcct ttggtaaaga
    55321 tgttgatcaa gaggataatc agaacagtaa tagctgcaag caagagactt tgaccagttg
    55381 gctctggaac gttatttccc atatttccaa tagcgacagg gatcaaggtt aaaccaatcg
    55441 tggtaataac agatcctgtt acgatagatg ggaaaagatt ggctactttt gagaagatgc
    55501 ctgaaacaag aaccacgtaa attccagatg cgataagggc accaaacata gcgctactac
    55561 catggctttg cccaatcata atcaagggag cgaccgactg gaatgcaact ccaagaacga
    55621 ctgggagtcc aatcccaaag tatttgttga gttggagttg gaggaaggtt gccaccccac
    55681 acatgaagat atctgtagaa atcaggtagg tcaactgctc agctgaatag ccaagggctg
    55741 tcgcaatcat gatgggaacc aggatagatc ctgagtacat ggctagtaag tgctgcaagc
    55801 caagaacggc tgcttgcgag tgtttttctt gagtttgcat tagagatctg cctccttaaa
    55861 tacgacctga ccattttcaa aacgatccaa acgagcaagt gataggacag ggtagcctgc
    55921 tttttcaagc aaatcacgac catcttggaa ggatttctca atcacgatac cgatagcttg
    55981 gactgtggca ccggcctgtt cgatgatttg aatcaagcct ttagcagctt ggccattagc
    56041 aaggaaatcg tcgataatca aaaccttatc ttctggtgag aggaattttc cagcgataga
    56101 aacggtgctg gtcacctgtt tggtaaagga gtagacttga gcagttaaga tgccttcgtt
    56161 catggtgatg ttcttagctt ttttggcgaa aatcatggga acgtttaagg cttcagctgt
    56221 aaaaacggct ggggcaatac ccgacgcttc aatggttacg accttggtaa tgccagtagc
    56281 agcaaatttt tccgcaaaaa ccttaccaat ctctcgcatc aagctaaagt caacttggtg
    56341 ggttaaaaag gaatctacct tgaggatgtt atcacccaag atatgcccat ccttgaggat
    56401 gcgctcttct aataatttca taagacctcc taaagtctaa aagttaattt acttgttgtt
    56461 taaatatttc tatagtgatc ccttttgcta atactatata tttgataaaa ctattacgag
    56521 cgaagcgagt cttatcaaat atttcccgtt gtagtggtat catagacaat aatcttgtta
    56581 ttgtctatga cgggattttt gagagtaaaa tagttcgggg aactatttta gcctaagcct
    56641 agaaatgaaa gagctagggg ctcaaaaatt agggatgaaa ttccctggat tcctgaaatt
    56701 attcacagga taatttcacc tcccgtccgc actaattaag ggaaatatta aaaatattca
    56761 aaaaaagacc tacttaatct ctaagtaagt cccccaaata ggcatggcaa aaacggccat
    56821 atctcactgc tgacttactt attgttaggt gttccggcac cttgtagaaa cgtcgtgcca
    56881 attcacgaca taaacaagta aaacgatatt caattttaaa taggcttgag ccaatgtttt
    56941 tattttacac taaataactt tagaaatcaa ctattttgtt agtgttttgg tttaaaaaac
    57001 gaacaaacag aagagagggc gaacaaaaaa ctccgttgta agctaacatt tatactaaat
    57061 gaaaatcaaa gagcaaacta ggaagctatc cacaacctca aatcactgtt ttgaggttgt
    57121 ggatagaatt gacagagtca gtatcatata cctacggtaa ggcaacgttg atgtggcttg
    57181 aagagatttt cgaagagtat tagaagattt ttccatcata aaaggcatac tatcaagttt
    57241 ttaaacacct gacaatatgc ctttttctaa ctttaaagac ttttcccaat ttttattatt
    57301 ctactcgcta aatcttaaaa aatagccatt tggatccaaa actgcaaatt catgaggata
    57361 gatatagtga tcactgacac gaaactttct cttggtcaag ggacgataaa taggatagtt
    57421 tgccttcatc actctttaat agagttttga aacatccttt atgccaaagg agagattgac
    57481 tccacgacca aatggatagg tcagttcagc tagttgatcc tttgttccct cctctaacat
    57541 tagttgacac tcttcaagag aaagagaaag ttttcttctg gacgttggta ttcaatccta
    57601 aaacccagta aaccacagta gaaggaccgg gactgttcga tattcgatac aagcaactcg
    57661 ggaatgaccg cattgtagtc catatagaaa atccttacaa gtcaatttcc aagacaatcg
    57721 gtgtatggtc ttggcgagca cctgagtcaa tcatatcaga tttagtgacc ttgtcagcga
    57781 tacggttact tgtgagccag tagtcgattc tccagcctgt attgttgatt ttagaagttt
    57841 tgctgcgttg tgcccaccaa gtgtagcgtt caggaacatc gccatgaaca tggcggaagg
    57901 tgtctgtaaa tccagttgcc aaaaggttgg taaatccagc acgttcctcg tcagtaaatc
    57961 caggtgaacg gcggttgcta gcaggatttg caaggtcgat ttcattgtgg gctacgttgt
    58021 agtcaccggt cgcaaggact ggtttttctt tgtctagttc agccaaatac tcagcatatt
    58081 tggcatccca gacttggcgt tcttccaagc gtttgagacc gtcaccagcg tttggagtgt
    58141 aaacttgggt tacgaaaaat gcatcaaatt ctagagtgat gatacgacct tccaagtcca
    58201 tggtagaagg ggcaccgatt tctgggaagc tgatagtagg tgtaagttct ttcttataaa
    58261 ggaacatggt tccagcatag cctttacggg caggctcttg ggaagaacgc cacgtgtttt
    58321 cgtagcctgg gaagagttct tctaaaattt ccacgtgttt ctttgtaggt cctttggcag
    58381 aaagcttggt ttcttggata gcaatgatat cagcattttc agcgaccaag gtttgtagga
    58441 cttcttggga caatttggca cgagctgagt cactagttag ggcagcgttt agggaatcaa
    58501 tattccatga gataagtttc ataaagttac ctttttcatt cagattatag attttattat
    58561 accaaaaaaa gatctatttc cccaacgtat agtttgaaaa attactctct ttcgtttata
    58621 attaagaatg attttatgaa agggagtgaa aatacatgaa attctactct tatgactatg
    58681 tactcagcca aatcggtcag caaaatggta tcatggttgg ctttgggatt gttctattag
    58741 ctgtgacagt ttttttgctt ttaaggcata ccatgataaa aagggaaccg aatttcgtga
    58801 gttggtcatg atttcagctc tggccttatt tagctctgct tttggtcagc atcacgactt
    58861 atcaaaacaa tcaagtttct aacaataaat ttcaaacttc acttcatttc atcgaggttg
    58921 tttccaaaga tttgggagta gacaagtcag aagtctatgt taatacttcc acaaacacag
    58981 atggcgcact tatcaaggtg ggagaacgct attatcgtgc cctaaacgga agtgagccag
    59041 acaagtacct gttagagaaa gtcgaattgt ataagacaga cgcaattgaa ctggtggatg
    59101 tgaacaaatg acacttaatt atatcgaaat tttaatcaaa ctggtcttga ctctcaaata
    59161 gctcaacaac aatgttcact ttgtgaaacg tttgattgat ggtaagccaa ctctccttat
    59221 caaaaatggg aatattgacc cataagcctg tcgttcagtt ggtttgtctg catcggatgt
    59281 agccctcaaa cttcgtagcc aagggatttt ccagatgaag caagtcaaac gagctgtgca
    59341 agagcaaaat gggcaactca tcgttgtgca aatgggagat gaaaatccta agtatccagt
    59401 tgtgactgac ggtgtgattc aagtagatgt cttggaatcg attggtcgta gcgaagagtg
    59461 gttgcttgat aacctcagta aacaagggca tgacaatgta gccaatatct ttattgctga
    59521 atatgacaag ggtgctgtta cagtcgtaac ttatgaaaaa gaaaaacctg gggtcttgta
    59581 ctcttcgaaa atctcttcaa accgcgtcaa cgtcgccttg ccgtatgtag gttactgact
    59641 tcgtcagttc tatctacaac ctcaaagcag tgctttgagc agcctgcggc tagtttccta
    59701 gtttgctctt tgattttcat tgagtattgg cctcaggttt ccatttgcaa tcagaaaggg
    59761 attttatgtc cattattcaa aaactttggt ggtttttcaa gttagaaaaa cgccgttatc
    59821 tagtcggaat tgtggccctg gtcttggttt ccgtcctcaa tctcattcct cctatggtta
    59881 tggggcgggt tattgatgcc atcacatcgg ggcaattaac ccagcaggac ctccttctta
    59941 gcctatttta cttgctactt gcagcctttg gtatgtacta tttgcgctat gtgtggcgta
    60001 tgtatatcct tgggacctct tattgcttgg gacagatcat gcggtctcgc ttgtttaagc
    60061 atttcacaaa aatgtcgtca gccttttatc aaacctatcg gacgggtgat ctgatggcac
    60121 acgcaaccaa tgatatcaat gccttgactc gtttagcagg tggcggtgtc atgtctgcgg
    60181 tggatgcctc tatcacggct ctggtgactt tgttgaccat gctctttagc atctcatggc
    60241 agatgactct tgttgccatt ctccccctac ctttcatggc ctatgcgact agtcgcctag
    60301 ggagaaagac tcataaggcc tttggcgaat cccaagctgc tttttctgaa ctcaataaca
    60361 aggtacagga gtccgtatca ggtatcaaag tgaccaagtc tttcggttat caggcagacg
    60421 agttgaagtc ttttcaggca gtcaatgaat taaccttcca aaagaacctg caaaccatga
    60481 aatatgatag tctctttgac cctatggttc tcttgtttgt tggttcgtcc tatgttttaa
    60541 cgcttttggt tggctccttg gtggttcagg aagggcagat tacagttggg aatctagtca
    60601 cctttatcag ctatttggat atgctggtct ggcctcttat ggccatcggc ttcctcttta
    60661 atactactca gagagggaag gtttcttacc agcggattga aaatcttttg tctcaggaat
    60721 ctcctgtaca agacccggag tttcctctgg atggtattga aaatgggcgt ttggagtatg
    60781 ccattgacag ctttgctttt gaaaatgagg aaacactgac ggatattcac tttagtttgg
    60841 caaaagggca aacactgggc ttggttgggc agacaggctc tgggaaaacg tccttaatca
    60901 agctcctctt gcgtgaatac gatgtggata agggcgccat ttatctaaac ggtcacgata
    60961 ttcgggacta tcgtctgaca gaccttcgca gtctcatggg ctatgttcct caggaccagt
    61021 ttctttttgc gacttcaatc ctagacaata tccgctttgg caatcctaac ttgccccttt
    61081 cagcggtcga ggaagctact aagctagccc gagtttacca agatattgta gacatgcctc
    61141 aaggatttga tacgctgatt ggtgaaaaag gagtcagtct ttctggtggt caaaagcaac
    61201 ggttggctat gagtcgggct atgattttag accctgatat cttgattttg gatgattcct
    61261 tatccgccgt agatgccaag acagagtatg cgattatcga caacctcaag gagacgcgaa
    61321 aggacaagac aaccattatc actgcccatc gcctgagtgc agttgtccat gcagatttga
    61381 ttttagtcct gcaaaatggt caaattatcg aacgaggcag gcacgaagac ttgctagctt
    61441 tggatggctg gtatgcccaa acctaccagt ctcagcagct ggaaatgaag ggagaagaag
    61501 atgcagaata aacaagaaca atggactgta ttgaagcgct tgatgtccta tctcaagcct
    61561 tatggactcc ttaccttttt ggcactcagt tttctcctag cgacgacggt cattaaaagt
    61621 gtcattcccc ttgtggcttc ccactttatc gaccagtatc tcagcaatct taaccaacta
    61681 gccgtgaccg ttttgctggt ctactatggt ctctacatcc tacaaactgt agttcagtat
    61741 gtcggcaatc ttctctttgc gcgcgtgtct tacagtattg ttagggatat tcgtcgggat
    61801 gcctttgcca atatggagaa actgggcatg tcttactttg acaagacgcc agcgggttct
    61861 atcgtttctc gtttgaccaa cgataccgag acgattagtg atatgttttc tgggatttta
    61921 tccagcttta tctcagcagt ttttatcttt ctgacaaccc tttataccat gttggtgctg
    61981 gattttcgtt tgacagcatt agtcttgctc ttcctcccct tgattttcct tttggtcaat
    62041 ctctatcgaa aaaagtcagt gaaaatcatc gagaaaacca gaagtctctt gtcagatatc
    62101 aatagtaagc tggcagagaa tatcgaggga atcaggatta ttcaggcttt taatcaagag
    62161 aagcgcctgc aggcagaatt tgatgaaatc aaccaagagc atttggccta tgccaaccgt
    62221 tctgtagcct tggatgccct ctttttgaga cctgccatga gtttgttgaa acttctaggt
    62281 tatgctgtct tgatgaccta ttttggctat cgtggtcttt ctatcgggat aacggccggg
    62341 accatgtatg cttttatcca gtacatcaac cgcctctttg accctttgat tgaggtgacg
    62401 caaaactttt caacactgca aacgtctatg gtttctgcag gccgtgtctt tgccttaatc
    62461 gatgagagga cctatgagcc ccttcaagaa aatgggcaag ccaaagtcaa agaaggcaat
    62521 atccgttttg aacatgtgtg tttctcgtat gacggtaaac atccgattct ggatgacatt
    62581 tctttctctg ttaataaggg tgaaaccatt gcctttgtag gtcatacagg ttcagggaaa
    62641 tcgtctatta tcaatgtcct catgcgcttt tatgaattcc agtcagggag agttctcttg
    62701 gatgatgtgg atatcaggga tttcagtcaa gaagagctga gaaaaaacat cggtttggtt
    62761 ttacaggaac ccttcctcta tcatggaact attaagtcca atatcgccat gtaccaagaa
    62821 atcagtgatg agcaggttca ggctgcggca gcctttgtgg atgcagattc ctttattcaa
    62881 gaacttcctc aggggtacga ctcccctgtt tccgagcgtg gttcgagctt ctctactggg
    62941 cagcgccagc ttcttgcctt tgctagaaca gtcgccagcc agcctaaaat cctgattttg
    63001 gatgaagcga cagccaatat tgactctgaa acagaaagtt tggttcaagc ttctctggcg
    63061 aagatgagac agggccgaac aactattgct atcgctcacc gcctttctac tattcaagac
    63121 gccaactgca tctatgtctt ggataaggga cgcattatcg agagtggaac ccatgaggaa
    63181 ctcttgactc tgggaggaac ctatcacaag atgtatagtt tgcaggcagg ggccatggcc
    63241 tatactcttt gaaaatctct ttaaaccatg tcagctttat ctgcaatctc aaagctgtac
    63301 tttgattttc attgagtact agaaggaaat ccttcaaatt acagatttct ttcaccgcct
    63361 tttccatttt gtggtataat gaaaaatgtt gacaaatagt ataataaaaa caaaggagaa
    63421 cagcatgctg aaatgggaag acttgcctgt ggaaatgaaa tcaagcgagg ttgagtctta
    63481 ctaccagctt gtctctaaaa ggaagggttc gctgattttc aagcgttgct tggactgggt
    63541 tttggccttg gtcttactgg ttctaacttc tcccatcttt ctcatcttga gcatttggat
    63601 caagttggat agcaaggggc cagtgattta caagcaagag cgtgtgaccc agtacaaccg
    63661 tcggttcaag atttggaagt tccgtaccat ggtgacggat gcggataaaa aaggaagtct
    63721 ggtgacttct gctaacgata gccgtattac caaggttgga aatttcatcc gacgtgtccg
    63781 tttggacgaa ctgcctcagt tggtcaatgt ccttaaaggt gagatgtcct ttgtcggtac
    63841 acgacctgaa gtgccacgtt atacagagca gtatagccct gaaatgatgg caaccttgct
    63901 cttgcaagca ggaattacct ctccagccag catcaactac aaggatgagg acaccatcat
    63961 cagtcaaatg acggagaaag gtctgtcagt tgatcaggcc tatgtggagc atgttcttcc
    64021 tgaaaagatg cgctataacc tcgcctatct ccgagagttt agtttctttg gggacatcaa
    64081 aatcatgttt caaaccgtgt ttgaggtact aaaataaagt agtcataaga aaatgagtac
    64141 agataaaagg agcaaatcaa tgccaaatta caatattcca ttttcaccgc ctgatatcac
    64201 agaagcagaa attgctgaag tagcggatac cctgcgttct ggttggatca caacaggtcc
    64261 taaaacaaaa gaactggagc gccgcttgtc tctttacaca cagacaccta agactgtttg
    64321 tctcaactct gcgacagccg ctctggagtt gattttacgc gttttggaag tgggacctgg
    64381 tgatgaagtc atcgttccag ccatgaccta tacggcttca tgtagtgtca ttacgcacgt
    64441 gggagcaacc cctgtcatgg tggatatcca agcagatacg tttgagatgg actatgacct
    64501 gcttgagcaa gctatcactg agaaaactaa ggtgattatc ccagtagagc tcgcagggat
    64561 tgtttgcgat tatgaccgtt tgttccaagt cgtggagaaa aaacgtgact tctttaccgc
    64621 ttcaagcaag tggcaaaagg cctttaaccg tattgtcatt gtctctgata gtgcccacgc
    64681 tttgggatct acttataaag gacaaccttc tggttctatc gctgatttta cttccttctc
    64741 attccatgcc gttaagaact ttacaacggc agaaggtgga agtgcgactt ggaaagccaa
    64801 tccagtgatt gatgacgaag agatgtacaa ggaattccaa atcctttccc ttcacgggca
    64861 aactaaggat gctcttgcca agatgcaatt ggggtcatgg gaatacgata tcgttacacc
    64921 agcctataag tgcaacatga ccgatatcat ggcttcactt ggtttggtac aattggaccg
    64981 ctatccaagt ttgttgcaac gccgtaagga cattgtggac cgctatgata gtggttttgc
    65041 aggttctcgc atccatcctt tggcacacaa gactgaaact gtcgaatctt cacgccacct
    65101 ctacatcacc cgtgtagaag gagcaagcct agaagaacgc aacctcatca tccaagaatt
    65161 ggctaaagca ggaattgcaa gtaatgttca ctacaaaccg cttcctctct tgacagccta
    65221 taagaatctt ggatttgata tgacgaacta tcctaaggcc tatgccttct ttgagaatga
    65281 aattaccctc cctcttcata ctaaattaag cgatgaagaa gtagactata tcattgagac
    65341 tttcaaaaca gtttctgaaa aagtgctaac tttatcaaaa aaatgacaaa ctacagtcaa
    65401 gcgaaagtga tcctgtcccc aaaaagtcta attgagtgta aaaactgttg ttttcaattg
    65461 ataatagttt acacctgtag ttgaggcctc tttctcctca gagagagaat ttttatagga
    65521 ttttcctttc ttgtgggagt cccgtggttt gaaataagat gtgagcaatt tggtgtagca
    65581 tttagaatcc ttactagaca tcatttagaa aatctagtgt cttgttctag ttttcaattc
    65641 accctatttt ttgaaagacg tgagtttcca tgagtgagat tgtggaaact cgcgtctttt
    65701 tttgttttca gaatattgtt caaagttttg tgcctgtctt tcatgttcta gtcattcttt
    65761 tgcatgatag aatttatagc atgttgatat tataataata cgaatatccc atatgtttag
    65821 tgatgcttgc tatacatcat tagatctcct gcgagacaat ctataaaaca cttgtctacg
    65881 attacctata tgccctattc cagtatttta gaagcactgc atctattttt atcgaggtta
    65941 aatctagctt ttatagaagg tctatttaag aaatatattg tagtgtttta gtttcaatcc
    66001 gccatatgag cgatattcag gtaaatatcc ctggcgaatg cttgtatgac aaggtatttg
    66061 ttctttcatt tataatttac aacatatcaa taaatttaaa tatagtaaat gggatatttt
    66121 atattcaagc taagaaagat agcatcactt ttgaatggaa ggctaaagag caaactagga
    66181 agttggccat agatagctca aaatcctgct ttgaggttgt agatatagta aaatgaaata
    66241 agaataggac aaattgatcg ggacagttaa atcgatttct aacaatgttt tagaagtaga
    66301 ggtgtactat tatagtttca gtctactata gaactgacca agtcagtaac ctagacttag
    66361 ggcaaggcgg cactgaccta gtttgaagag atttccgaag agtataaatt ttaatatttt
    66421 cttgtgttat tccttgacaa ttcaatttgg aaaatatatg ataaagataa tgacagcggt
    66481 gtcactctat ctattttaag aaaagtaata atcaattgtt aaaaaatagt aaaaaaattg
    66541 gaggttctga tgaaatattt tgttcctaat gaggtattca gtattcgtaa attaaaggtg
    66601 gggacttgct cggtactatt ggcaatttca attttgggaa gccaaggtat tttatcggat
    66661 gaagttgtta ctagttcttc accgatggct acaaaagagt cttctaatgc aattactaat
    66721 gatttagata attcaccaac tgttaatcag aatcgttctg ctgaaatgat tgcctctaat
    66781 tcaaccacta atggtttaga taattcgtta agtgttaata gtatcagctc taatggtact
    66841 attcgttcca attcacaatt agacaacaga acagttgaat ctacagtaac atctactaat
    66901 gaaaataaga gttataagga agatgttata agtgacagaa ttatcaaaaa agaatttgaa
    66961 gatactgctt taagtgtaaa agattatggt gcagtaggtg atgggattca tgatgatcga
    67021 caagcaattc aagatgcaat agatgctgca gctcaagggc taggtggagg aaatgtatat
    67081 tttcctgaag gaacttattt agtaaaagaa attgtttttt taaaaagtca tacacactta
    67141 gaattgaatg agaaagctac aattctaaat ggtataaata ttaagaatca cccttccatt
    67201 gtttttatga caggtttatt tacggatgat ggtgcgcaaa tagaatgggg cccaacagaa
    67261 gatattagtt attctggtgg tacgattgat atgaacggtg ttttgaatga agaaggaact
    67321 aaagcaaaaa atctaccact tataaattct tcaggtgcat ttgctattgg gaattcaaat
    67381 agcgtaacta taaaaaatgt aacattcaag gatagttatc aagggcatgc tattcaaatt
    67441 gcaggttcga aaaatgtatt agttgataat tctcgttttc ttgggcaagc cttacccaaa
    67501 acgatgaagg atgggcaaat cataagtaag gagagcattc agattgaacc attaactaga
    67561 aaaggttttc cttatgcctt gaatgatgat gggaaaaaat ctgaaaatgt gactattcaa
    67621 aattcctatt ttggcaaaag tgataaatct ggggaattag taacagcaat tggcacacac
    67681 tatcaaacat tgtcgacaca gaacccctct aatattaaaa ttttaaataa tcattttgat
    67741 aacatgatgt atgcaggtgt acgttttaca ggattcactg atgtattaat caaaggaaat
    67801 cgctttgata agaaagttaa aggagagagt gtacattatc gagaaagcgg agcagcttta
    67861 gtaaatgctt atagctataa aaacactaaa gacctattag atttaaataa acaggtggtt
    67921 atcgccgaaa atatatttaa tattgccgat cctaaaacaa aagcgatacg agttgcaaaa
    67981 gatagtgcag aatatttagg aaaagtatca gatattactg taacaaaaaa tgtaattaat
    68041 aataattcta aggaaacaga acaaccaaat attgaattat tacgagttag tgataattta
    68101 gtagtctcag agaatagtat attcggtggt aaagaaggaa ttgttattga ggattcaaag
    68161 ggtaaaataa ccgttttaaa taaccaattt tataatttat ccggtaagta tatatcattc
    68221 atcaaatcta atgcaaatgg gaaagaacct gttatacgtg atagcgatgg taatttcaat
    68281 attgtaacgg agaatgggct ttacaaaatt gtaacaaata atttaagtga taaaaacgaa
    68341 aaagaaaaaa acaaagagga aaaacaatct aattcaaata atgtaattga tagtaaccag
    68401 aagaacggag agtttaactc aagtaaagat aatagacaaa tgaatgacaa gatcgacaat
    68461 aaacaagata ataagacaga agaagtaaac tataaaatag ttggagatgg cagagaaact
    68521 gaaaatcata ttaataaatc taaagaaata gtagatgtaa aacaaaaatt accaaagact
    68581 ggttcgaaca agattatgga actattctta acagtgacag gaattggttt acttttgaca
    68641 ctaaaagggt tgaagtatta tggtaaagat aaataaaatt tgttcgatac aaggaagttc
    68701 cgtagaaaat gaggatattg taggttcaca aaatcagtat ttttggatta ttggtggagc
    68761 tacagattta tataattcta aagaggagat aggttattca gtctcagaag ttgtacatat
    68821 tttatcagaa agtttgtcgg ttaattgtaa agaatcaaaa actcttaaac aaatatttga
    68881 aactgcttta ctcgaggtta aagatgaaat cggtttaaac tcatatgaat taacagagta
    68941 tagtaaaatg aaataataat aggacaaatc aatcaggaca gtcaaatcga tttctaacaa
    69001 tgttttagaa gtagaggtgt actattctag tttcaatata ctatattatc gcttaccaat
    69061 atttgctaaa ctttcagaaa aaaagttgga gtatatgatg ctaggtgact gcgtcatgtt
    69121 agtaaacgaa atggaaataa ctgatcatag agtagataac ttatttgaaa aagggaaaaa
    69181 tgagataaaa gattcaagta gtagatttag caataggaca tataaaagct ttagaaaaag
    69241 tatctgaaaa aacagatgtt tatatctata acctaggctc gggagaaggc actagtgtat
    69301 tacaacttgt aaatacattt gaaagtgtta ataagatccc tattccttat aaaatagttc
    69361 caagacgttc aggagacgtt gcaacttatt atgcaaatgc agacaaagca tataaggaat
    69421 taaattggag gacaacaaaa tcgattgaag acatgtgtag agatacatgg aattggcaat
    69481 caaaaaatcc caatggctat aattgatgat actgtctata tgagtgctgt attttggaaa
    69541 aattacttaa ccttttaatg aaagataaat taaaaaaaat atttgacagc gcttgacaaa
    69601 ggaaacggtt tcattgtata atgtaaacac aatgacaccg atgtcaaata taaaaaagaa
    69661 ggtctttata tgaaaaactt aacaaaaatt aagttcaaag aaaatgggga atttaatcat
    69721 ttccctggga atacagttgt agcaaatctt tatactaaac aagatttgat ggaagttgtt
    69781 gatattattc aatcacgtta tagagaatta ccatttatcg ataagtttac tttaactcca
    69841 aggaattcta ttcacatgac tgtaattgaa ttgttgtgcc atgaaaatcg tgaaacggag
    69901 ttttggagca gtaatcttcc tctagataca cctttacagg aaatacatga ttactttgct
    69961 aaacaacttg aaatttttcc attgttggat gaagaaattt atatgcgtat aactgaaatg
    70021 ggaaaacaaa acatactagt tgaacctgca gatgaagctt ctgcaaagag attagaagaa
    70081 attcgtactt atgtctcaga aaaagcaggt gtttgtttcc ctaatcatga tagatatcaa
    70141 ttccatattt caattgggta tcttcggatt cctctaaccg aagaggagga agaagagttt
    70201 actaaagtca gagcagaatt aactgaaatt ttattagaga agattccaac tattactgta
    70261 aaccgtattg actatactgt atttgaagat atgagacaat ttgttccata tcacgaaaaa
    70321 tttaaataaa ataataaaaa aggagaactt atcatgaaaa aaatgaaagt ttggtctact
    70381 gtacttgcaa cgggagttgc tcttactaca cttgctgctt gctctggagg ttcaaattct
    70441 acgactgctt cttcatctga agaaaaagct gataaaagtc aagaattagt aatctattcg
    70501 aactcagtct caaatggtcg tggtgattgg ttgactgcta aagcaaaaga agctggtttt
    70561 aatataaaaa tggttgatat tgctggcgct caattagcag accgtgttat tgctgagaag
    70621 aataatgcag ttgcagatat ggtatttgga attggtgctg ttgactcaaa taaaattaga
    70681 gatcaaaaat tactagtaca gtacaagcct aaatggttag ataaaattga tcaatcttta
    70741 tcagataaag ataattatta taatcctgtg attgttcaac cattagtttt aattggggcg
    70801 cctgatgtaa aagaaatgcc taaagattgg actgaattag gtagtaagta taaaggtaaa
    70861 tattcaattt atggtcttca aggtggtaca ggacgggcaa ttctagcaag tatcttagtt
    70921 cgttaccttg atgaaaaagg agatttaggc gtatcagaaa aaggatggga agttgcaaaa
    70981 gaatactttg caaatgccta tactcttcaa aaaggtgaaa gctcagttgt taaagcgtta
    71041 gataaagaaa gcccaattca atacggtatg atctggggtt ctggagcgtt aatcggacaa
    71101 aaagaacaaa atgttgaatt caaagttatg actcctgaga ttggtgtacc atttgtaact
    71161 gaacaaacta tggttttaag cactagtaaa aaacaagcgt tagctaaaga atttattgat
    71221 tggtttggtc aatcagaaat tcaagtagaa tatagtaaaa aatttggctc tatccctgcc
    71281 aataaagatg ccctaaaaga gttacctgaa gatacgaaaa aatttgttga tcaagtgaaa
    71341 ccacaaaata ttgactggga agctgttgga aagcatttgg atgaatgggt agaaaaagct
    71401 gaattagaat acgtaaaata agaaataaga gttatttttt atgtccaagt ctctctatta
    71461 tttctaaatt taaggaagaa ataaagagag gcttttggtt tagtaataga gggagttagt
    71521 gagatgatta aatttgataa tattcaaatt aaatatggtg attttgttgc aattgataat
    71581 ctgaatttag atatacatga aggggaattc tttacatttc ttgggccttc aggatgtggt
    71641 aaatcaacta ctttgagagc attggtaggt tttttagatc catcatcagg aagtattgaa
    71701 gttaatggaa cagatgtcac tcatttggaa cctgaaaagc gtggaattgg tattgtattt
    71761 caatcttatg cgctatttcc aactatgact gtttttgata atattgcatt tggtttaaaa
    71821 gttaagaagg tagctccaga tgttattaaa gctaaagtat cagcagtggc agcaaaaatt
    71881 aagatctctg atcaacagtt acagcgtaat gtatcagaat tatctggggg tcaacaacaa
    71941 agggtagcat tggctcgtgc tctggttctt gaacctaaaa ttctttgtct agatgaacca
    72001 ttgtcaaacc ttgacgcaaa attacgtgta gatttgagaa aagagttgaa aagacttcaa
    72061 aaagagttag gtattactac tttatatgtt actcatgatc aagaggaagc cttgacttta
    72121 tctgatagaa ttgcagtctt taacaatgga tacatcgaac aggtcggtac accagtagag
    72181 atttatcata attctcaaac tgaatttgta tgtgatttta ttggagatat taatgttttg
    72241 accgatgaaa cagtccacga agtattattg aaaaatacaa gcgttttctt agaggataaa
    72301 aaaggataca ttcgattaga gaaagttcga ttcaatcgtg aaactgaaca agattttatt
    72361 ctaaaaggga caattattga tgttgagttt tctggagtta caattcacta tacaataaaa
    72421 gtttctgaaa gtcagattct taatgtaaca agtattgata gtcaggctgc tattagatct
    72481 gtcggagaaa gtgtggaatt atttatcata ccatcagacg ttctgcaatt ttaaggaggt
    72541 gcagtatgcg tcataaatta aatttaaaag attggcttat tcgtttaggg ttaatctggt
    72601 tcttagtaac atttattatt tatccaaact ttgatctagt agtgaatgta tttgtaaaag
    72661 gaggagaatt ttcccttgat gctgtacatc gtgttctaaa atctcagagg gcacttcaga
    72721 gtattatgaa cagttttaag ttagcatttt cactcattat tacagttaat gtcgtaggta
    72781 ttctttgtgt tctatttaca gagtactttg atattaaagg tgctaaaatt ttaaaattag
    72841 gttatatgac ctctttaatt tatggaggag tggttttagc gactggatat aaatttgtct
    72901 atggtcctta tggattgatt acaaaatttt tacaaaatgt tatcccttct ttagactcta
    72961 actggtttat tgggtatggt gcagtcttat tcattatgac attttcagga actgctaatc
    73021 atacattgtt tttaacaaat acaattcgaa gcgttgacta tcacactatt gaggctgctc
    73081 gaaatatggg agcaaaacca tttactgttt tccgaaaagt agtgttacca accttaattc
    73141 caactctatt tgcacttact attatggttt ttcttagtgg tttatctgca gtagcagcac
    73201 ccatgattgt tggtggtaaa gaatttcaaa ctataaatcc aatgattatt acatttgcag
    73261 gtatggggaa ttctcgtgat ttagctgcct tacttgcaat tattttaggt attgcaacta
    73321 caattttgct tactatcatg aataagatag aaaaaggtgg aaattatatt tctatctcta
    73381 agactaaagc gcctcttaaa aaacaaaaaa ttgcgtctaa gccttggaat atcattgctc
    73441 acattgtagc atatggattg ttcacagttt tcatgcttcc actaattttt atagtattat
    73501 actcatttac agatccagtt gcaattcaaa caggtaactt aacattatca aactttactt
    73561 tagaaaatta tcgcttattc tttagtaata gtgcggcatt ctctccattc ttggtcagct
    73621 ttatttattc tattattgct gcgacaacag caacaattct cgcagttgta tttgctcgtg
    73681 ttgtcagaaa acataaatct cgttttgatt tcttatttga atatggtgct ctacttcctt
    73741 ggttactacc aagtacactt ttagcagtaa gtttattatt tacttttaat cagccacaat
    73801 ttcttgtctt gaatcagatt ttggtaggta gtttggtaat tctacttatt gcatatatag
    73861 ttgtaaaaat cccattttct tatagaatgg tacgtgctat tttatttagt gttgatgatg
    73921 agatggaaga tgcagcaaga agtatgggtg cttcaccttt ttatactatg atgaaggtta
    73981 tcattccatt tattttaccg gttgttctct ctgttattgc tttaaacttt aactctttat
    74041 taactgactt cgacttatct gtattccttt accatcccct agctcaacca ttaggtatta
    74101 cgattcgatc tgcaggtgat gaaacagcaa catctaatgc acaagctctg gtatttgttt
    74161 atacaattgt tctgatgatt atttctggaa cggtattata cttcacacaa agaccggggc
    74221 gtaaagtaag gaaataatca tgacagccac tagtcttggg ttatcaaata ttgaaatagt
    74281 tgtcaggatt gttttatcag tagtcattgg tagtataatt ggtttagaga gagggagcaa
    74341 atcccagcct gcaggcatcc gaacttatag tattgtttgt ctagctgcat gtttgattat
    74401 gatgacgaat gagtacgtat cttataaatt tgggacagga gatcctacac gattaggagc
    74461 tcaagttata tcaggtgtgg gttttctagg cgctggaacg attcttatta cagataaaaa
    74521 gaaaattaca ggtctgacaa ctgcagcagg catttgggct tcggcaggaa ttggattagc
    74581 tattggagta ggtttttatg agggagctct tttagtagcc atttctgttt ggggtgtgat
    74641 atccatgttc caaccactaa aaaaatatct gcaaaatcgt tctaaaatga ttgaattgta
    74701 tatagtggtt aaatctacag aagcctataa tcgtgtattg gtttattgtg cagaaaatgg
    74761 tatcagaatg accgattcaa gaacagcgtt tggagatgtt aattctgaca gaattgaata
    74821 ctttgatgtt ccagacaaaa aaatagcgtc atttattact ctggaattat caggtagatt
    74881 tgaacatctt cgactgatgg aagaaattgc taatattgta ggtgttattt atgtcgaaga
    74941 aattagctga aatttagtaa acaaagggac agatgttttt gtccttttgt tttttagatg
    75001 ttttaatcat ctaatttttg agtagatttt tgctcagagg tttttatgaa agattataaa
    75061 atcaattttg atttag
//
LOCUS       DAVLTT010000003        70547 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLTT010000003 DAVLTT010000000
VERSION     DAVLTT010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 70547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70547
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.003"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(<1..171)
                     /locus_tag="VYN15_000173"
     CDS             complement(<1..171)
                     /locus_tag="VYN15_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1451568.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVS"
     gene            complement(184..957)
                     /locus_tag="VYN15_000174"
     CDS             complement(184..957)
                     /locus_tag="VYN15_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1451569.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGIGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(1405..2160)
                     /locus_tag="VYN15_000175"
                     /pseudo
     CDS             complement(1405..2160)
                     /locus_tag="VYN15_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(2298..3920)
                     /gene="groL"
                     /locus_tag="VYN15_000176"
     CDS             complement(2298..3920)
                     /gene="groL"
                     /locus_tag="VYN15_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV1451570.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(3936..4220)
                     /gene="groES"
                     /locus_tag="VYN15_000177"
     CDS             complement(3936..4220)
                     /gene="groES"
                     /locus_tag="VYN15_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV1451571.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(4490..4885)
                     /locus_tag="VYN15_000178"
     CDS             complement(4490..4885)
                     /locus_tag="VYN15_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV1451572.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVIEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(4962..5723)
                     /locus_tag="VYN15_000179"
     CDS             complement(4962..5723)
                     /locus_tag="VYN15_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1451573.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTHCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(5756..6382)
                     /locus_tag="VYN15_000180"
     CDS             complement(5756..6382)
                     /locus_tag="VYN15_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV1451574.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVACLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(6398..6715)
                     /locus_tag="VYN15_000181"
     CDS             complement(6398..6715)
                     /locus_tag="VYN15_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV1451575.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(6712..7011)
                     /locus_tag="VYN15_000182"
     CDS             complement(6712..7011)
                     /locus_tag="VYN15_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV1451576.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            7099..7179
                     /locus_tag="VYN15_000183"
                     /pseudo
     CDS             7099..7179
                     /locus_tag="VYN15_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(7308..7499)
                     /locus_tag="VYN15_000184"
     CDS             complement(7308..7499)
                     /locus_tag="VYN15_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV1451577.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(7660..8334)
                     /locus_tag="VYN15_000185"
     CDS             complement(7660..8334)
                     /locus_tag="VYN15_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451578.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(8340..8786)
                     /locus_tag="VYN15_000186"
     CDS             complement(8340..8786)
                     /locus_tag="VYN15_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1451579.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(8900..9403)
                     /locus_tag="VYN15_000187"
     CDS             complement(8900..9403)
                     /locus_tag="VYN15_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1451580.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(9400..9762)
                     /locus_tag="VYN15_000188"
     CDS             complement(9400..9762)
                     /locus_tag="VYN15_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV1451581.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(9828..11693)
                     /locus_tag="VYN15_000189"
                     /pseudo
     CDS             complement(9828..11693)
                     /locus_tag="VYN15_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(11725..12174)
                     /locus_tag="VYN15_000190"
     CDS             complement(11725..12174)
                     /locus_tag="VYN15_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1451582.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(12298..13014)
                     /locus_tag="VYN15_000191"
     CDS             complement(12298..13014)
                     /locus_tag="VYN15_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1451583.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(13895..15310)
                     /gene="ply"
                     /locus_tag="VYN15_000192"
     CDS             complement(13895..15310)
                     /gene="ply"
                     /locus_tag="VYN15_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV1451584.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(15321..15653)
                     /locus_tag="VYN15_000193"
     CDS             complement(15321..15653)
                     /locus_tag="VYN15_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451585.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(15724..16332)
                     /locus_tag="VYN15_000194"
     CDS             complement(15724..16332)
                     /locus_tag="VYN15_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451586.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(16345..16803)
                     /locus_tag="VYN15_000195"
     CDS             complement(16345..16803)
                     /locus_tag="VYN15_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV1451587.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            16928..17327
                     /locus_tag="VYN15_000196"
                     /pseudo
     CDS             16928..17327
                     /locus_tag="VYN15_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18092..18352)
                     /locus_tag="VYN15_000197"
     CDS             complement(18092..18352)
                     /locus_tag="VYN15_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451588.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELELVKSTILQNDDISLDQNEIFEILKNFFDG"
     gene            complement(18411..18962)
                     /locus_tag="VYN15_000198"
                     /pseudo
     CDS             complement(18411..18962)
                     /locus_tag="VYN15_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(18952..19149)
                     /locus_tag="VYN15_000199"
     CDS             complement(18952..19149)
                     /locus_tag="VYN15_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451589.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(19153..19737)
                     /locus_tag="VYN15_000200"
     CDS             complement(19153..19737)
                     /locus_tag="VYN15_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451590.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDGEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(20145..20570)
                     /locus_tag="VYN15_000201"
     CDS             complement(20145..20570)
                     /locus_tag="VYN15_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451591.1"
                     /translation="MTSRVFIDADCISVFLWVSAEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILVEAFKA"
     gene            complement(20699..21058)
                     /locus_tag="VYN15_000202"
     CDS             complement(20699..21058)
                     /locus_tag="VYN15_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451592.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKKMILV"
     gene            complement(21104..21310)
                     /locus_tag="VYN15_000203"
     CDS             complement(21104..21310)
                     /locus_tag="VYN15_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451593.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(21297..21458)
                     /locus_tag="VYN15_000204"
     CDS             complement(21297..21458)
                     /locus_tag="VYN15_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1451594.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(21804..22760)
                     /gene="lytA"
                     /locus_tag="VYN15_000205"
     CDS             complement(21804..22760)
                     /gene="lytA"
                     /locus_tag="VYN15_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV1451595.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(23136..24506)
                     /locus_tag="VYN15_000206"
     CDS             complement(23136..24506)
                     /locus_tag="VYN15_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1451596.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(24813..25979)
                     /gene="recA"
                     /locus_tag="VYN15_000207"
     CDS             complement(24813..25979)
                     /gene="recA"
                     /locus_tag="VYN15_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV1451597.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(26034..27290)
                     /locus_tag="VYN15_000208"
     CDS             complement(26034..27290)
                     /locus_tag="VYN15_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV1451598.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(27375..28391)
                     /locus_tag="VYN15_000209"
     CDS             complement(27375..28391)
                     /locus_tag="VYN15_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1451599.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(28399..28917)
                     /locus_tag="VYN15_000210"
     CDS             complement(28399..28917)
                     /locus_tag="VYN15_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1451600.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLID"
     gene            complement(28907..29350)
                     /gene="tsaE"
                     /locus_tag="VYN15_000211"
     CDS             complement(28907..29350)
                     /gene="tsaE"
                     /locus_tag="VYN15_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV1451601.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(29437..30057)
                     /locus_tag="VYN15_000212"
     CDS             complement(29437..30057)
                     /locus_tag="VYN15_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451602.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(30440..31303)
                     /locus_tag="VYN15_000213"
     CDS             complement(30440..31303)
                     /locus_tag="VYN15_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1451603.1"
                     /translation="MSTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            31649..33664
                     /locus_tag="VYN15_000214"
     CDS             31649..33664
                     /locus_tag="VYN15_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1451604.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWFIFLRPVGEDLKAIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGEGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            33666..34298
                     /locus_tag="VYN15_000215"
     CDS             33666..34298
                     /locus_tag="VYN15_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451605.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            34537..34731
                     /locus_tag="VYN15_000216"
                     /pseudo
     CDS             34537..34731
                     /locus_tag="VYN15_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260348.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="competence damage-inducible protein A"
     gene            complement(35241..35654)
                     /gene="ndk"
                     /locus_tag="VYN15_000217"
     CDS             complement(35241..35654)
                     /gene="ndk"
                     /locus_tag="VYN15_000217"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV1451606.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(35765..39442)
                     /gene="rpoC"
                     /locus_tag="VYN15_000218"
     CDS             complement(35765..39442)
                     /gene="rpoC"
                     /locus_tag="VYN15_000218"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV1451607.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYRRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(39475..43086)
                     /gene="rpoB"
                     /locus_tag="VYN15_000219"
     CDS             complement(39475..43086)
                     /gene="rpoB"
                     /locus_tag="VYN15_000219"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1451608.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            43502..43572
                     /locus_tag="VYN15_000220"
     tRNA            43502..43572
                     /locus_tag="VYN15_000220"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43534..43536,aa:Cys,seq:gca)
     gene            complement(43770..45101)
                     /locus_tag="VYN15_000221"
     CDS             complement(43770..45101)
                     /locus_tag="VYN15_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV1451609.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(45392..46216)
                     /gene="endA"
                     /locus_tag="VYN15_000222"
     CDS             complement(45392..46216)
                     /gene="endA"
                     /locus_tag="VYN15_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV1451610.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLNQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(46255..46443)
                     /locus_tag="VYN15_000223"
     CDS             complement(46255..46443)
                     /locus_tag="VYN15_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1451611.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(46436..47719)
                     /gene="murA"
                     /locus_tag="VYN15_000224"
     CDS             complement(46436..47719)
                     /gene="murA"
                     /locus_tag="VYN15_000224"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1451612.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(47743..47973)
                     /locus_tag="VYN15_000225"
     CDS             complement(47743..47973)
                     /locus_tag="VYN15_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV1451613.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALGGLL"
     gene            complement(48031..49068)
                     /locus_tag="VYN15_000226"
     CDS             complement(48031..49068)
                     /locus_tag="VYN15_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV1451614.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(49052..49540)
                     /gene="coaD"
                     /locus_tag="VYN15_000227"
     CDS             complement(49052..49540)
                     /gene="coaD"
                     /locus_tag="VYN15_000227"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV1451615.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(49530..50069)
                     /gene="rsmD"
                     /locus_tag="VYN15_000228"
     CDS             complement(49530..50069)
                     /gene="rsmD"
                     /locus_tag="VYN15_000228"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV1451616.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKVVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(50134..51126)
                     /locus_tag="VYN15_000229"
     CDS             complement(50134..51126)
                     /locus_tag="VYN15_000229"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV1451617.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(51239..51922)
                     /locus_tag="VYN15_000230"
     CDS             complement(51239..51922)
                     /locus_tag="VYN15_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV1451618.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(51978..52718)
                     /locus_tag="VYN15_000231"
     CDS             complement(51978..52718)
                     /locus_tag="VYN15_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV1451619.1"
                     /translation="MTIITSKANSVVKNTKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            52752..53030
                     /locus_tag="VYN15_000232"
     CDS             52752..53030
                     /locus_tag="VYN15_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV1451620.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYPDFKIAN"
     gene            53108..54034
                     /gene="yidC"
                     /locus_tag="VYN15_000233"
     CDS             53108..54034
                     /gene="yidC"
                     /locus_tag="VYN15_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1451621.1"
                     /translation="MKSIKRFALSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPSKASAFST
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(54109..54903)
                     /gene="pflA"
                     /locus_tag="VYN15_000234"
     CDS             complement(54109..54903)
                     /gene="pflA"
                     /locus_tag="VYN15_000234"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV1451622.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDILTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKQLMDTESYQDYMKRVHG"
     gene            complement(55029..56279)
                     /locus_tag="VYN15_000235"
     CDS             complement(55029..56279)
                     /locus_tag="VYN15_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV1451623.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERAAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     LWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTPAGLGQVKIFTELGRFM
                     LAPHGALLTRVTHKKKTYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEVVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(56346..57173)
                     /gene="purR"
                     /locus_tag="VYN15_000236"
     CDS             complement(56346..57173)
                     /gene="purR"
                     /locus_tag="VYN15_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV1451624.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(57439..58380)
                     /locus_tag="VYN15_000237"
     CDS             complement(57439..58380)
                     /locus_tag="VYN15_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV1451625.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(58370..59626)
                     /locus_tag="VYN15_000238"
     CDS             complement(58370..59626)
                     /locus_tag="VYN15_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV1451626.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(59628..60290)
                     /locus_tag="VYN15_000239"
     CDS             complement(59628..60290)
                     /locus_tag="VYN15_000239"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV1451627.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKGAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(60253..60909)
                     /locus_tag="VYN15_000240"
     CDS             complement(60253..60909)
                     /locus_tag="VYN15_000240"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1451628.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(60920..61798)
                     /gene="rsgA"
                     /locus_tag="VYN15_000241"
     CDS             complement(60920..61798)
                     /gene="rsgA"
                     /locus_tag="VYN15_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV1451629.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(61800..62672)
                     /gene="rsmA"
                     /locus_tag="VYN15_000242"
     CDS             complement(61800..62672)
                     /gene="rsmA"
                     /locus_tag="VYN15_000242"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV1451630.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLSIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(62953..63111)
                     /locus_tag="VYN15_000243"
     CDS             complement(62953..63111)
                     /locus_tag="VYN15_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451631.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEG"
     gene            complement(63104..63745)
                     /locus_tag="VYN15_000244"
     CDS             complement(63104..63745)
                     /locus_tag="VYN15_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451632.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(63747..65777)
                     /locus_tag="VYN15_000245"
     CDS             complement(63747..65777)
                     /locus_tag="VYN15_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1451633.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIASGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRIMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(65854..66150)
                     /locus_tag="VYN15_000246"
     CDS             complement(65854..66150)
                     /locus_tag="VYN15_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1451634.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(66470..67380)
                     /locus_tag="VYN15_000247"
                     /pseudo
     CDS             complement(66470..67380)
                     /locus_tag="VYN15_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(67452..68012)
                     /gene="rnmV"
                     /locus_tag="VYN15_000248"
     CDS             complement(67452..68012)
                     /gene="rnmV"
                     /locus_tag="VYN15_000248"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV1451635.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMMVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(68012..68785)
                     /locus_tag="VYN15_000249"
     CDS             complement(68012..68785)
                     /locus_tag="VYN15_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV1451636.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(69090..69983)
                     /locus_tag="VYN15_000250"
     CDS             complement(69090..69983)
                     /locus_tag="VYN15_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV1451637.1"
                     /translation="MVAQDPKAQDSTKLTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPASKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(70267..70401)
                     /gene="rpmH"
                     /locus_tag="VYN15_000251"
     CDS             complement(70267..70401)
                     /gene="rpmH"
                     /locus_tag="VYN15_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV1451638.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        20548 a        15889 c        12871 g        21239 t
ORIGIN      
        1 cgaaacattg atatttgata ataattcaaa aaatgttgaa agagaaattt cattttctcc
       61 cctttcaaat ctagaaagtt gagattttga tatagaatca gctgcagcat actctaaaga
      121 atatccgttt aattttctaa aatatcgaaa agcttctccg taatttttca cactttcatt
      181 cccttaactt tcttttcgag cgataaacat accatattct ttaggaatga tcaacatacc
      241 attattaaac tcactttcca atcttttacg tattatttcc tcttctagtg aacctatttc
      301 tgaaattcct ttaaacgatt ggatgtattt aactaggtca tctatactag ttacctgtaa
      361 ctcatcatca tagagtaatg tatcgacaga gttaaaatac ctactcaggt accttttacc
      421 attttgtaaa gtaaacgttc tattttctaa atcttgatta acctcatctt taaataaact
      481 tgccaaataa tttacaactc cattttcacc aaatgtagca cagtaaaaaa ttcctccggt
      541 ttttaagacc ctattcacct cagagagagc tttaggaata tcattcacat gatgtagaag
      601 catattagca ataacaatat caaaagtttc attctcaaaa gaaatctttt gaatatccat
      661 tatctcataa ttgacattgt ttctatttcc aatcactgac ttcgttgatt ttaccatatc
      721 tttagaaaaa tctgtaacaa tcaactgctt cattttatct atagaatcac tattactttt
      781 ccacaattct cctataccac atcccaattc tagaaccttt acttcatcag tgatttggta
      841 gttagaaaat atccaattat taaatcccaa tttatttttt gaatacttct tatgcaattc
      901 tactcgaata tcaagattat catgactttt atattgttca attactttat caatcatttt
      961 aaatgacctc cactctataa tttggcatta tatcacaaga ataaagatag tgttaaataa
     1021 gttgtataaa tgcaaaaaag gaataaatcc attatagcag agttacaaca cattactaga
     1081 aagagattta ttcctacgac tcagtttggc atgcttaact tcctaactca aaaacaaagc
     1141 atcgattaat ttatccgttc ttcttttgaa acagatttga actgataatt gctcgtttta
     1201 atttaagaag ctcttttgag caaaacttca tttttttaag agtccaacaa tttctgtcta
     1261 tcgcttttct actagcaaaa aaacctacct tgaggcaagt tttcatttat atatctaatt
     1321 tcgtaatagt atagtaaaat gaaataagga cagtcaaatc gatttctaac aatgttttag
     1381 aagtaaaggt gtactattct agtttcaatc tactataaat ttgatatgag aatagtcttt
     1441 ctcaacatcc ttacccaaca agaatgctgt agcgtccttc ttaacttgaa ccaggtcaat
     1501 attctgggct tgggctgcat agacgcagcc acaataacat tgacgataga tatcatactc
     1561 ctcacacatc tctactgaac gtttgtagcc ttgatttttc ttgaaatcgt tgggaagata
     1621 gtgggtcgtg taaatttttt gcacatcgat tccgatgctg ttgatggttt gagaattctt
     1681 atgaggactg atggtcaagg ctgaaccaaa gtagtcaaag cccaagtcca tagccacttg
     1741 cgctgtttta tccagtcggt agtcaaaaca aaccttgcaa cggtcgccac cttcgggctc
     1801 ctcctctagt cccctaacta gttttcggta ttaattgggt tcgtagggag cttctaggta
     1861 ctgaaccgta tttcctgtcc gctcattaaa atcactaaca aatttcttgg tgacatagac
     1921 ccgcttatgg tattctacct tgggatggat attagaattg gcaaaataga tggtcacatc
     1981 tgcatacttg gtcaaatatt ctagtgtata ggtactacaa ggggcacagc aaacatgcac
     2041 gagaatggtt ggccgttgct catttttcta ccatacttct accattttct gcatgacacg
     2101 gtcataatta atcttctgat tggggggcat cttgcacaga atttcttcta catcgatcat
     2161 gttcttctcc tttttctagt cttattttat catataagtt aggagagctc aaatcaattt
     2221 agaagtgaat attataaaaa gaagggttag tcattccctc cttttgtgtt ttttataagt
     2281 tgttttctat agaatgctta catcatcccg cccatcatgc ttggatccat tgctggagct
     2341 ggggctactg gttctggttt attggctacg actgcttctg ttgtcaaaat caagctggct
     2401 acagatgctg cattttgtag ggctgaacga ctcactttaa ctggatcaat gataccttga
     2461 tcaatcatgt taacccactc gccagttgct gcgttaaatc ctataccaag ctcagcattt
     2521 ttcaaacgat cgataacgat agatccttca aatcctgcat tgtgagcaat ttgacgaacg
     2581 ggttcttcca aagcacggag aacaatatta cgtcctgttg cttcatctcc tgtcaattcc
     2641 aaggtagcaa cagctggaat cacattggca agagctgttc caccacctgc aacaatacct
     2701 tcttcaacag ctgcacgagt agcgttgagg gcatcttcaa tgcggagttt catttctttc
     2761 aactcagttt cagttgcggc tccgacctta ataaccgcta caccacctga caatttggcc
     2821 aagcgttctt gcaatttttc acggtcaaat tcagaagttg tagtttcgat ttgagacttg
     2881 ataaccgcaa cacggtgaga aatcgcttca ggatttcctg caccttctac aataaccgtg
     2941 ctatctttgt ccacggtcac tctcgctgct tgaccaagag cttcaattgt cgcatctttc
     3001 aactcaagac caaggtcttc tgtgataact gttccgcctg ttaagatggc gatatcttca
     3061 agcatggctt tgcgacggtc accaaaacca ggtgccttga ctgctactac gttgaaggtt
     3121 ccacgaatct tgttcaaaac aagagttgga agagcctcac catccacatc atccgcaata
     3181 atcaagagtg gacgattgct ttggagaatg ctttccaaaa gtggcaagat ttcttggata
     3241 ttggaaattt tcttgtctgt aatcaaaatg tacggatttt caaggtcagc caccattttt
     3301 tcgctatctg tcaccatgta ctgtgaaagg taaccacggt caaactgcat tccttctacg
     3361 acttcaagct ctgtttccat accacgtgac tcttcgatgg tgatgacacc gtctttgcca
     3421 actttttcca ttgcttcaga gatgtactca ccaacttttt cagaacgaga agatacggct
     3481 gcaacttgag cgatagcttc tttattggca acagggatgg cgttgttttt caaagcttca
     3541 actgctgcgg caactgctgt ttcaatccca cgacgaatac cgattggatt tgcacctgct
     3601 gtgacgtttt tgattccttc acggacgata gcttgggtca agactgttgc agtcgtagtt
     3661 ccgtcacctg cgatatcatt ggttttagaa gctacttctg atactaactt agcacccata
     3721 ttttcaaaat ggtcttccaa ttcgatttct ttggcaatgg tcacaccgtc attggtaatc
     3781 aagggtgaac cgaatgactt ttcaagaacg acattgcgac cttttggtcc caaggttact
     3841 ttaacagtgt ctgcaaggat atcgacacca cgaaccatgg ctgaacgggc atctgatgaa
     3901 aatttaattt cttttgacat acttactttc tccttctatt cctcaatgat tgccaaaatg
     3961 ttagcttcgc ctacgataat gtacttttca tcgccatctt tgacatcaag acctgcgtgg
     4021 gcttcaacta agacacgatc tccagtttta acacttggag caaccaagtc accgttcaag
     4081 gtacgaacac cttgtccagt agccacaact tgagctgttt tggttttttc ttgggctgag
     4141 cctgcaagga caaagccccc aacggtttgt tctttttctt ctatttttaa gaccacacgg
     4201 tcccctaatg gtttcaacat ctgatttcct ccataatgag atagatatta ttagcactct
     4261 ttgaactgga gtgctaattc ataattctat tgtatcactt ggtcagaaat agtcaagaaa
     4321 aaagtctgac tttctcaaga taaaaagcct gagaccaact cagacttttt aatgtttata
     4381 ctcaatgaaa atcaaagagc aaactaggaa gctagccgca ggctgctcaa agcattgctt
     4441 tgaggttgtg gataaagcta acgtggtttg aagagatttt cgaagagtat taaaatggca
     4501 attcttcctc ttccaagacc aaatctgcca aatcttggcc tgcattattt tcacgcatgg
     4561 cacgttgagc acgactttct aagagttgga atcctgtcac aaggacttcg attacatagt
     4621 tcatctgacc atttttctca aagcgacggg tacgcaattc tccatcaacg gaaatgagac
     4681 tacctttggt tgcgtagctt gccaaagttt ctgctagtct gccccatagg accatattga
     4741 caaaatcagc ttcacgttca ccgttttggt ctttgtaacg acggttgaca gcgatagttg
     4801 ctcgcgctac cgacttgtca ttgttggttt tgtgcaattc tggtgtagac gttaaacgcc
     4861 caatcatgat aactttatta tacatatttt cttcctccta cttatctatt cgtaggaaat
     4921 caaaaaagtt acagaaattt gtaacttttc gaggaaattt cttatttttt atgaatcatg
     4981 aaacctgtcg cctgttgatt ggccataatg gtcatatctg taatctgaac acggcgaggc
     5041 tgactggtca catagactac tgtgtctgca atatcctgag cttgcaaggc ttctattcct
     5101 tggtaaacgg acgcagcccg ctctttatca ccatgaaaac gaacagttga gaaatctgtt
     5161 tcgacaatcc caggctgaat ggttgtcacc ttgatatccg ttgcgatggt atcaattcgc
     5221 agtccatccg aaaaggtctt aaccgctgcc ttggtagctg agtaaacagc ggcaccagca
     5281 taggcgtaga ttcctgcggt tgaccccata ttgataatat gaccttgatt gacttttatc
     5341 attgctggca agaaacagtg agtaaccgcc atcagacctt taacattggt atccaacatg
     5401 gtcaacatat ccaactcctc atagtcttga tagggagcca agtcaagagc cagtccggcg
     5461 ttgttgacca agatatcaat cctccctatc gtttctagaa tatcagagca aacagtcttc
     5521 accatgacca tatccgtcac atctagtgga aaagtccaga cggtttgatt tggaaagctt
     5581 actgcaaact ccgacttgag gatttctaat ctgtctatcc gtcgtcctgt tagaacgaca
     5641 tcctcaccct gctccagata agcacgcgca atcgcttcac cgattcctga ggttgctccc
     5701 gtaatcacta cattttttgc catcttattt ccttctatca gatgctgaca agttcctagg
     5761 cagtccagtg tttcgctggg tcgaacggtg ttccgacaac ttggtcttct gataattcaa
     5821 gcaccccacg tttttgcgga gcatttggca aatgcaattc acgaggacta cacatcatcc
     5881 caaaactctt ttcaccacga agttcgcctg ggaaaatgaa attccctttt ggcatcatgg
     5941 caccaggaag agccacaatg gttttcaacc caacacgcgc attaggtgct cctgcaacga
     6001 tttgcactat cttgtcactt gcgactgcaa cttggcagat gttgaggtgg tcactatctg
     6061 gatgggctac catctcaaca atttcaccaa caacaaactt aggttccttg tcattaacaa
     6121 tttcttctgt aaaaccttcc gcctgtaatt cttggttcaa acaagcgact tgctcatctg
     6181 ataaaaagac ttgacctcgc tctgcaattt caaacaagct cgaaacctca aaaatgttcc
     6241 aagctactgt ttccccattt tctttgagga aaacacgggc taccttgcct ttgcgttcca
     6301 cattcagttt ggcatctccg ctatttttca cgatgaccat aaggacatca ccgacatgtt
     6361 ctttgttata tgtaaaaatc attgtttact ttttctccta tttcaatcct gctaaaaaat
     6421 cgttaatttg ctccttactt ttacggtcgc gattgacaaa acggccgatt tccttgtcct
     6481 tttctagaac aacaaggcta ggaattccgt aaacatccca gagtttggcc aaatccatat
     6541 actgatctcg gtccattcga ataaaggtga actctggatt ggtctcctca atctctggta
     6601 aggcaggata gatataacgg caatcgccac accagtccgc cacaaaaagg aagaccttct
     6661 taccgtcttt ttctactaaa gatgccaatt cttctaaact tgctggttgt atcataagac
     6721 ttcctcctca tagactaggt cttcattttc atagacaaaa gtataatgac ggccatcctc
     6781 aaaaatgacg ccaccaagca agctctctag actgctttca tagacttgaa catagagggt
     6841 cgcaatttcc cccatgtctg aaaaatggtc tcgtacaatc gctgtcaact cttcctgagt
     6901 cttcatgagc ttatggtcat ctgcaacttt tttcgtagca agggcaaggc tcccaatacc
     6961 aagcagagcc agacctgcca tccacatttt tttagctttc ataccattca ttttaacaca
     7021 aaaaaggctt taggacaaat gaggaaacag caaaaaagca agtaaaaagc ctcttccttt
     7081 aaggaaaagg acttcttata ctcaatgaaa atcaaagacc aaactagaaa gctagccgca
     7141 ggctgctcaa aacacggttt tgaggttgta gataaggcga cgctgacgtg gtttgaagag
     7201 attttcaaag agtattattc ttattgccag gcacctaagt tgccaacgta gtaaccatca
     7261 ggtgtgtagg tattgcgaag catcttacct gatgaagcca gataatacta cttgccattg
     7321 tctttgaccc aatcattcgc aatcatggaa ccagaagaac ttacataata ccattctccc
     7381 ttgtcataaa cccaagtact gactttcatg gttcctgagc aattaaaggc aaaaaaactg
     7441 tccaatatca ttcgtttttt aaaagcattt gacactacat catctacgct gtagtacata
     7501 gatacatcaa acgtaaaagc caaaatatcg aaaaatatac aacttttaaa ggcagcattt
     7561 cattttttaa agtctaacaa ccatagaact gaaatcagag caaggcatca atttcctact
     7621 cttagtacgt ctattttgat ggttgaagtg aagatttttt tatttaacgt agacaatttc
     7681 caacttccca aaagccacat ctccacggat agtcaaggtt ttgctggttg gggctacagg
     7741 agcgtcagcc ttagctgcac caaaggaggt ttctactttc aaatctacac gccagtgttg
     7801 tggaacatag acggttgcat ttccgaaggc cacttcaata tttaaagttg caaaatcacc
     7861 tagcatctct gcattatcat agtagatttt agcatcccca aaagcgactt ccacttggtc
     7921 atctacgaga tcttgatctt gcttatagaa ggtcccgcta ccaaaagcga cttccttatc
     7981 cgtgacgact gtttttttcc cattgtacca ccattttttt tcattccaga acttacttga
     8041 atgcgtcaga taaccaacac caagtaccac caagatgcta gcccaaataa gagaatgatt
     8101 ggtaactggt aacaagtcat aagcgtaatt tgcaatgatg agcgccagta aacctgtaaa
     8161 aactgccgaa gtgagatgac gtctaaggat ggactcaatg gacttataag caaaaaaaac
     8221 aatacctagt aaaggccata ttttaccatc caaagaagga attccaaaat tcccttgcag
     8281 caagatccaa gctgctaaaa ccaataaaac aataccaaat gctttctttt tcatgttttt
     8341 tacctcatgt ttcttagatt ttcttttagg agggattggt aatgccgtga gacatgaacc
     8401 tccttgtgcg tctgataaaa ggaaatggtg cccgttcctg aaaaggactt gtccactgag
     8461 taaatctgac ggatgtttgc gatcgttgac ttggaaactc gattaaaata gcgaggcaag
     8521 atagactcca actcatagag cttgaggcga acctcataag cttccttctg gttatgagcg
     8581 tagatcttgc tcccttctgt ttcaaagaag agaatttctg acaggtctag ataatattca
     8641 cctgtcccct tgtaaaaagt caacctcgga gcctttgact cttgcaagag ccgttgcaag
     8701 tctgcaattt catctgtcaa agtgggggtc ttgatgacaa tttcagtctc ctctaaattg
     8761 ccgtcaatct caattcgtaa cttcatcaca tctcctttct gactctacta tatcaaagct
     8821 aagttaggaa tacaagggca aaaaagcaag tggtcaattt gaagcagtaa gtggttgtag
     8881 gactagctta acttacatgt cagaatagga agaaaaggaa tccccacacc aaaccacaag
     8941 catagccaac caagacatcc ttgggataat gaacaccccc taaaaccctc accaacccca
     9001 gcaaagctga aaagatcaag catactaagc caataggtag actagcatgc agacaggcca
     9061 tggagatgat agttgccgaa aagacatggc gactgggcat cgaccgtccc gaactatcct
     9121 tatcaagaag gggacagata tcccaagttt cataaggtct cgggtgattg attttcttac
     9181 gaaacaggga caaggccaca aaacctgatg caggaataag cacataaacc ccaacttgct
     9241 gaccaagtcc tagttgcaga taagtggtga ctagcaagat cagatagacc aggggcatgg
     9301 cgactgtcat caaacgattg aaactgcgta ataggaataa aagaattgga cgactagtta
     9361 gtctggagct gatatttcga taccattctt gataattttt catttatgct tctcatactt
     9421 ttctagaact tgttgagatg ttttcccctt ggcaagccaa tccactagct tgtccaagcg
     9481 acgtatttcc tgcatcagag gatcatcaat ttcctcaata cggacaccgc aaatcttccc
     9541 tgtaattgca attcgttcag ggacataata tggtgcttgt ctaaaaaaat ctccgtaagt
     9601 aacatcccta tccagacaag caagaacatc actcacttca taccctgtca accaactggt
     9661 cacttggtga actgactctg cctttccacc ctttcgctca acttttgcaa tcaaggctaa
     9721 gtagacagca gcaaatttca tattgtataa tttctgactc atacttctct ctttctatgt
     9781 gtactagtat aaataagaaa aagaaggccg tcaagccttc ttttgattta ttcttctgct
     9841 tcatcttctg taaattgact attgtacaag tcagcgtaga agccaccttg cgccatcagt
     9901 tcctcatagt tgccttgctc gatgatattt ccatctttca tgaccaagat caagtctgca
     9961 tttcggatgg ttgacaagcg gtgggcaatg acaaaggatg tgcgtcattc catcaaacgg
    10021 tccatggctt tttggatcaa ttcctctgtc cgtgtgtcaa cagaagaagt cgcctcatcc
    10081 aaaatcaaaa gcggtgcatc cttaagaagg gcacgagcaa tagtcaatag ttgtttttgt
    10141 cctacagaca aggtcacggt gtcatccaag atggtatcat agccatctgg caaggtcata
    10201 ataaagtggt gaattcccac agccttacta gcttccatca ttcgttcatc actaatccct
    10261 atttgattat agatgagatt gtctcgaata gttccttcaa agagccaggt atcctgcaag
    10321 accattgaaa aggcatcatg cacttctgaa cgcgtcatag ccttggtatc cacaccatca
    10381 atgcgaatac ttcccttatc aatctcatag aatttcatca aaagattgac aatggttgtc
    10441 ttaccagccc cagtcggccc aacaatggca accttttgac cagcatgagc tgtcgcagag
    10501 aagtcatagt cttgaacatt gacaccgtcc accagaattt ctcctgctga cacgtcgtag
    10561 aaacgtggaa tcagattgac cagagttgat ttaccagaac ctgttgaccc aataaaggcc
    10621 actgtttgac cagtttctgc tttaaatcta acatgttcaa taactgcctc cgaatttgcc
    10681 gcataacgga aggtcacatc cttaaactcg acctgacctt tgaagttttc atcagccagc
    10741 tgcacttgag cagggttttg gatagaagaa tgcaaatata aaacttgatt aatccgctta
    10801 gcagagacca tagttcgggg aagaaccatg aagagtgctc ccacgagaag gaagcccatg
    10861 acaacctaca tggcataaga catgaaaaca atcatgtcac taaagaaagg cagacgcgct
    10921 atcggagcag cgtcgttaat cacataggtc ccaatccagt aaatcgccac actcaaacca
    10981 cttgaaatcc ccatcatgat aggattcaaa atagccataa gacggttgac aaacaaattc
    11041 aaacgggtca attcatcatt tactgctgca aatttttcat tttgataatc ctctgcattg
    11101 taggcacgaa cgacacgaat acctgttaaa ctctcacgag tgatactgtt cagtttatct
    11161 atcagcccct gaatcaagga ctgttttgga aagtctagcg tcatcaaaac ggtcgtcatc
    11221 aggacgttga caatcactgc cacaagtacg gcccaaagcc agtattctga atgacctaaa
    11281 atcttcccaa tagcccagat agccataatt ggaccacgcg ttaccacttg caagcccata
    11341 gtaatcaaca tttgaacttg agtaatgtca ttggtagtac gcgtcaagag gctaggaatt
    11401 gaaaatttct taatctctgt ctgcgagtaa tccaaaactc ggttaaaaat atcacttctc
    11461 agcctactag tataagaagc cgccactcgg gatgcaaaaa atccaactgc aactacggac
    11521 aagaaggcaa gaaagagcat tcccatcatc atgcttgccg gctgccacaa ctcatctaaa
    11581 ttagttactt gactacctag caaatccgta attttcgaga tataggtcgg cacttccaac
    11641 tctagataga ccgaaaagca agtaaagaga atggctagta aaatcatccc cattcttttc
    11701 tactaattct tttggctaat ttctttattc tctcctccta ttcccttgat attttgcctg
    11761 tagttgaccg agaaccttct caaaaatcag taattcatct tcatcaatgt cttccatcaa
    11821 ctgcttgtct atgcgttcaa aaaaagcctt aacctgttgc atctgagaac gtgctttgtc
    11881 cgtcagacga acaaacttag cccgcttatc aacaggactc gcctccaatt ccaccaaacc
    11941 attttgcact atacgcttaa ccagattact agcaacagac ttggtaatat tgagttcctg
    12001 ctcgatatct ttaatcaaga ccaagtcttg gtttttctcg cgattatcca aaaaatgcac
    12061 aacctgacct tgcggcccac ccataaattc aatgccgcaa cgtttggctt ccttttgcac
    12121 catcaggtga atttgatgac caaaacgctt aaagactaac atcggtttat ccataatctc
    12181 ccccttctaa ataaaaagag ttctctggag aataattaaa tttctatgag aactattttc
    12241 ttgattaaaa aaatcccaag tgattttctc acttaggatc atgttctata ggttaaatta
    12301 aaacccatct acgttcgtat aaatcttttg gacgtcttcg tcgtcttcaa gaacgctgta
    12361 aagtttttca aaggtttcaa ggtcttcgcc tgacaattcc acttctgact gaggaatcat
    12421 ttccaattca gtcacttgga attcttcaat accagactca cggagggcaa cgatagcctt
    12481 gtgaaggtca gttggcgctg tgtaaactgt gattgtacct tcttgtgctt ctacgtcatc
    12541 cacatccaca tccgcttcga gcaattgctc aaagactgcg tccgcatctt cacctccaaa
    12601 tacaataaca cctttattgt caaagaggta agaaacagaa cctgaagcgc ccatgtttcc
    12661 gccgttttta ccaaaggctg cacggacatt ggctgctgta cggttgacgt tagaagtcaa
    12721 agtatccaca attagcatag agccatttgg cccaaaacct tcgtaacgtc cttctgtaaa
    12781 ggtttcgtct gtgtttcctt tggctttatc aatcgcttta tcgataatgt gttttggcac
    12841 ttgggcttgt ttagcacggt cgataacgaa tttcaaagct gagtttgatt ctggatctgg
    12901 atcacctttt ttagctgcta catagatttc tacaccaaat tttgcatata ccttagagtt
    12961 agctccatct ttagccgttt tcttggctac gatattggcc catttacgtc ccattaggaa
    13021 tctccttttt tcacatttta atctttatta ttataacaca agtttttttg attttcacta
    13081 gaggaaatgg attttattag caaatcaagc taggatagca ctttacctgc taagatggtc
    13141 ttacctttct atctttatca acagacactc atccacattc aaaaaacaaa ctagaccatt
    13201 atctgcaaat agaaagtttc agccaagttt gacaaagtca gctcaaatta ctgtttgaag
    13261 tttgtagata taagcgacaa aaacaatcat actgcacctt ttgttgacag tctactccag
    13321 acatatcata gttcaagtaa atactttgaa attcaacagt tcttataggc gctattgtat
    13381 tctaagaaat caatagaaga gtttctaagc aaacctctaa tactcaataa aaatcaaaga
    13441 gcaaaccaga aagctagccg caggttgctc aaaacactgt tttgaggttg cggatggggc
    13501 tgacatggtt tgaagagatt ttcgaagagt ataatttacg tgttcccaag atggagaagt
    13561 tagactagta cactggcact tctaaaccat tgctagcaat tgatttgttc atatttaatt
    13621 tcattttttc cataaatggg tattagatat aaacagcaaa atatttccga tacgtgtcgt
    13681 tcttgaattt ccaatcatct aaaacaagta aaggataatc aatcccctgt atatcaagga
    13741 attggctacc ctttttactt ttttacacat tctgtttgat agattcattt taacatcacg
    13801 agcatactcc aatggaaatc gctaggcaag agataaactt tcagatatcc gcaaagagat
    13861 catcgcctct ttttgtcgca agcattctcc tctcctagtc attttctacc ttatcttcta
    13921 cctgaggata gagagttgtt ccccaaatag aaatcgtccg cttacgcact agtggcaaat
    13981 cggttttttc ataaaccgta cgccaccatt cccaggcaag cccggtacac tctctaattt
    14041 tgacagagag attacgaaca ttccctttta aaggaatact agtggtaaag tgagccgtta
    14101 aatcctgccc atttctgtcc caagccttag gagtcaagac ttccttacct tgatgatcat
    14161 aggataattc attccaagta atataatatt gggcaacata ggcaccacta tgatccagca
    14221 gtaaatctcc gtttctgtaa gctgtaacct tagtctcaac atagtctgta ctattttgaa
    14281 aggtcgcaac tacattgtca cgtaaaaaag aagttgtata ggaaatcggc aagcctggat
    14341 gatctgctgt aaagcgactg ccttcttgaa tcaagtcctc taccatatcc accttgcctg
    14401 ttacaactcg ggcacccgaa cttgggtcgc cccctaaaat aaccgccttc acttctgtat
    14461 tgtccaaaat ctgcttccac tctgtctgag gagctacctt gactcctttt atcaaagctt
    14521 caaaagcagc ctctacttca tcactcttac tcgtggtttc caacttgaga tagacttggc
    14581 gcccataagc aacactcgaa atatagacca aaggacgctc tgcagaaatt cctctctgtt
    14641 ttaaatcctc taccgttaca gtatcttgaa acacatctcc tggattttta acagcgtcta
    14701 cgctgactgt ataataaatc tgcttaaaat taacaatctg aatctgcttt tcgcctgaat
    14761 ggacagagtt aaaatcaata tcaagagaat tccctgtctt ttcaaagtca gaaccaaact
    14821 tgaccttgag ttgttccatg ctgtgagccg tgattttttc atactgcatt ctagctggga
    14881 cattattgac ctgaccataa tcttgatgcc acttagccaa caaatcgttt accgctccgc
    14941 gaacacttga attgctgggg tcttccactt ggagaaagct atcgctactt gccaaaccag
    15001 gcaaatcaat actataagtc atcggagcac gatcgaccgc aagaagagtg ggattattct
    15061 ctaacaaggt ctcatccact acgagaagtg ctccaggata gaggcgactg tcgttggtag
    15121 ctgttacaga aatatcactt gtatttgtcg acaagctccg cttctttctt tcgataacaa
    15181 caaactcatc gggtagctga ttaccctctt tgatgaaacg attttcaata ctttctccct
    15241 gatgggtcaa gagtttcttt ttatcgtaat tcatagctag tataaagtca tttactgctt
    15301 tatttgccat cttctacctc ctaataagtt cctggattga gttgcataaa ctcagacttg
    15361 ttcagcgaaa tcagccgtgg ttggactaag tgatccaaaa tttcctcgta caattcttct
    15421 gagacattgc gtcgccgtct ggctagataa gaagtcggaa taaccgtatt atccaacata
    15481 aataccttat ctaagtcaat caaggttggt cttgtaaaag gattacgagc tagatccggc
    15541 tcttctatca taaagttctt gaccaaacgt ctggtcaaga gagctggttt gaaggtctga
    15601 tttttaacca actctttgtt tttagtcatg ctgttgtcaa tacagatata catatgattc
    15661 ttcacagcca aatcgctact aatagtcgga aaaggcaaat aaagaactac aacatctcct
    15721 ctcttaatca agcaagagca cccccttttc tcctaatgta acatagacag gattgaccaa
    15781 gtcttctgat tgactcagaa tttccaaagt ttgagtttgg cgcgctgtca atttagtagc
    15841 atcttgtctc ttcaatacaa aatgcttgtc accaataacc ttgacaatat aatccttctc
    15901 caaagctgac tggtaaatcc acatcagatg ttgtctgtcc tgagaactca agagagaagg
    15961 attttcaagc ctcccgatag tctgataaaa atcaaaaaca ggagctaact cctgccaatc
    16021 tgattggcta gttgtcaagg ctagaaaaag ggctttgcga gctgatactt cttggttagc
    16081 cttgagagtt actttcccct ccaagttttt tagaaatcgg gaaactccag aaagcaaatt
    16141 tttctctaac tgcgagaaat aaaaaccttt cgttcccaga cataagtctt tcatgtcgct
    16201 ttctctagca aataagagct caaacatttg atagtaaaag aaaaatatct ggcactgggt
    16261 cgcgctcatc ttttccttat cggcttcttt ttttaaccag agcaagggcg acaggtagct
    16321 ggattgagac atttcctcta cctcctactc ttttttaact ggagcatctg cactagctgc
    16381 cacttctttt gactggatac tttcccactg gttaatctcc tctgagataa gaccttcgca
    16441 tgtcttgaca aatagggcaa aagccttggt ctttcctgca tatttctccg tttggcattg
    16501 atagaggaat ttttctttct ccaggagttg cgcagttttt tggtaagaaa tccaattttc
    16561 ctttgcatta tacaaattga taatcccctc acacagcaag ccgagactgg ataaggcaac
    16621 cgaaatcaaa cggtagcgat cacctggcat aggaatagca caaaagacag ctatgaggaa
    16681 acctgccacg atttctgtta tttttaatac cttatagcgc ctacgatgtt gaacgctttt
    16741 ctttaaaaaa tgagctatct gtacgtctaa tcgctctgtc aggtacattt cttctggcgt
    16801 catattcgta actcctttca tttactttga taaccatagt ataacatatt tgaatatcaa
    16861 agtatagtaa aaactggact ataacttatt agacttcctg cgaaacaaaa tatggtatag
    16921 tagttctatg aattatgaag caagtaaaca actaactgat gcacgattta agcgtcttgt
    16981 tggtgttcag cgtaccactt ttgaagagat gttagctgta ttaaaaacag cttatcaaaa
    17041 aagtcagaca agctggtaaa atcttggctg acagtggtta tcaagggctc atgaagatat
    17101 atcctcaagc acaaactcca cgtaaatcca gcaaactcaa gccgctaaca gttgaagata
    17161 aatcctgtaa ccatgcgcta tctaaggaga gaagcaaggt tgagaacatc tttaccaaag
    17221 taaaaacgtt taaaatgttt tcaacaacct atcgaaatca tcgtaaacgc ttcggattac
    17281 gaatgaattt gagtgctggt attatcaatc atgaactagg attctagttt tgcaggaagt
    17341 ctattatata tatgcacaga catatgaaat ctttttgata cagccttctt tttacataga
    17401 gagacagcag ttatgatata tttatccatt cacaacatct tctgtaccaa tactacaata
    17461 attggtacat tttgattaca caatcgtttc aaaaaatatg atggaagact gagtatttta
    17521 tagtaattcc cttcctatca actagatcaa ccagttgagt gttgaatgtt gaaacaccct
    17581 agcctcagca aaggactatg atcagcattt cctagccaat aggacgctcc aaatcaccta
    17641 ttctaagtcc atcactagct tggtcagtaa gatacagact gcaaggcaag actgacgtgg
    17701 ttgatgagat tttggaagag tattacaatc atagattcac cagtagactt gaccgcagat
    17761 ttaactatag tagattgaaa ctagaatagt acacttctgc ttctaaaaca ttgttagaaa
    17821 tcgatttgac tgtcctgatc aatttgtcct gttctcgttt cattttacta tactaaaaaa
    17881 ccacctgaaa caaatcaagt gactagagga taaaaacaaa gactgggcaa aaagttttga
    17941 aaagcaaaaa acgcataata tcaggtcttg aaaaaccttg atactatacg tttgattgtg
    18001 ggaagattga cttcattttc tcctgaaatt gaagtttttt ctagtttcca ggtatagacg
    18061 aattcaatat agccatctcg ctacaattat tttaaccatc gaaaaaattt ttcagaattt
    18121 caaaaatttc attttgatct aatgaaatgt catcattttg aagaatagtt gacttcacaa
    18181 gctctaattc tatcacaaag cggtgcatgt ctgcttttac cgcactactt gatgttatag
    18241 ccgataactt ttcatctcct agcaaggaag ctgtcaaacg ggtaaggtca ttcaaatgct
    18301 ttttaatgga cttacttaaa ccttgagcac ctgtagcaga gcgttccctc atatccagcc
    18361 aagctttagc cttaaaaata attaatactc aatgaaaatc aaagagcaaa ctaggaagct
    18421 agctgcaggc tgctcaaaac actgttttga ggttgtagat ggaagctgac gtggtttgaa
    18481 gagattttcg aagagtatag accacaatta ctcaataccg aatacccctg aatggtttct
    18541 ttttcatgca ccaatatatt ataataatct tcatccaata ataaggctga taaactagca
    18601 tcttggtcaa aatgtaaggg aatttctcga ccgtccttct ttaatggata ttctggtaag
    18661 atactaaata gttcaatcat agaaggaaac tcaggattag ttgttgtaaa tcgaaaaagc
    18721 tacgctttct catctttctg acttccttga tactctccca attctaaaaa atgattcaag
    18781 gtagtataaa attccttatt ttttacttca tcaatgatga ccatatcata atcttttgtt
    18841 gtgcgacttt taaatccttg cgaatccaat acgatagagg tagcagttcc cccaatcaga
    18901 acataatagt tctgaaaatc cgcaaacatt tcttgaaaaa taactttcgt attagctggc
    18961 atcatcttct cccagatact gtaatatcat attttctagt gcttcactct cttcctctat
    19021 acgtgggtca tcatcatctt ttaaggtcaa ataaagagaa atcggatcta caaattgttt
    19081 atcatgatta tttttaaaat cattccaaaa ctcagataca aaaggacgat atttccatat
    19141 ctctagcatc tttcatttta aaacatgctg agaaagtggc aaggataact gattgaattt
    19201 tctctgccat atgacatagc tagtattttc atccgtttca gctaaaaaag ttgaatgcga
    19261 caaagcataa gcaccaccat atagaaggtt agaaacagat tttatctgct ttatatcgcc
    19321 atctggcaat aaaaaggcaa tccacgttaa ttgttcgcta ggtgttaatt ccttagggac
    19381 ttcagtatca ttcgcattca gtactagtcc caatggaggg aagaagaggt ttcccttaaa
    19441 gtctacaaac ggaactctag cttgaagtaa ttgctttttt tcaccgtctg ataacttcga
    19501 aaacaccaaa acaacatcca tattggcttt ttcacccata gtgcgagcct gagtaacaaa
    19561 tgaactcaaa ctcccccttc tcttttcttt aatcaataaa aatgattcct tatgaaaagt
    19621 catttgagta tactcaaacc tttttacaaa actgattggt aaagtcaaag tcagttcctc
    19681 aatactgaca tcaacataaa aggattgaaa aattgacatt atctttttga cattcatgtt
    19741 ttttccttat tctatcattt ttattatatt ttatcattcg gtataataaa atataagttt
    19801 tttgataaaa taaccaaaaa ctactcgcta tcccctctca cattacccta catatcgttt
    19861 gacatgcgac tgatagttca ggaaaacttc aaggagaact tttctctcat ccactatgca
    19921 ggacttacta tttcacttct actcctatag gctcaatttg acacttttct ttttcgaatt
    19981 gctcatatgc ctcctgaata gtgagttcga tttatccaaa tttatttttg tctattttga
    20041 tgaatacttc cacgaagata gtctgaaaat gaatttgcac caattttcct tctcttttta
    20101 agcatattat tccagatatg attgccctct tgttcagtaa taaattacgc tttaaacgct
    20161 tcaaccagta tatctcctgt tgtcatatgt tctaaagaaa attcttctac atatggttta
    20221 acatctctta ggttattact tcctaatatc ccattatgct ttttcgctaa ggaaatagaa
    20281 gccgcttctc ccttaccaat aatcttgtta ctatcatgat ttcttgttaa atctctatat
    20341 aatgcgtatt cttcagttcc aatgtctatg ctcacaatct cagctgaacc cttagctacc
    20401 aactgatcta tcctagattt taaatgggga attgtaggta tattgatttc atcatacacc
    20461 tcttgtggaa taacaatttt acccaaatag agcttttcta aaagatgttc agcgctaacc
    20521 cataaaaata ctgaaataca atctgcatca ataaatacac gactagtcaa acgacaactc
    20581 ccccctcttc atctagccca tatacaatat catatctgaa agcatctagt aacagttcct
    20641 catacttccc ctgcgaaatt ctgttatttt ctaaaagttg ttcagttgaa ttaacatatt
    20701 atactaatat cattttcttt ttactttctg acaaaggacg atataaactt gtatcatagc
    20761 ctaatcttga agctgtctct ataacactaa tatccatatt tttaatttct tctgcatcaa
    20821 ggtatccatc attcctcaat ctatataaca tagctttatg actgatacca taaaactgac
    20881 ccaattttat aatatcttct acttcaagat gagttctatt ggcattttct ctgatttcct
    20941 caaccatcct atacagtgaa gatgggaaaa ttaaaaaata agaagcaaac tgatccgctt
    21001 ttctttcagt ttcatctcct tcaccaatca agataagact gactgaactc ttcttcacct
    21061 catcataata aagatgatac agtccatgtg ctaaagaaaa tctttacctt cctaatggca
    21121 tgtctgaatt gactgcaatg agactgaact gagttccttt ataacagact ccgctaatat
    21181 tctttccgag tccataaaat accagcgtca aattttctat cttttgtacc aatttaaaaa
    21241 tatctatcgg cgattcacca tcagctccca acttttttct aagatttgaa gctttattac
    21301 ttaaatccat tcgtgatatt cctttcacct ttttccattt tggcaatcat gctttgattc
    21361 aaagacaaat actcagcaat cttatcttga gtaagatttg aagatattct aagttctttt
    21421 attctttttc caacatcaca tacatttatc atattcatac acctctcata aaaagaatag
    21481 cacactcttg tcataatttt ttaaataaaa aaattatgac aaaacaagga agcaatttat
    21541 tgatgctgct taaaaatcta agattgatga gttcctatca aaaatcgcat cttcaacctc
    21601 aaaacagtac ttaaagctat ccgactcggt ttacattgtc aaatttagat tttatttgag
    21661 cataactttc tagtttgctt tctgattttt gtttaatata gtagcaaaca ttgaaggaaa
    21721 tatctccaca aaaaaacgca tactattaag ctttttcaag acctaataat atgcgctgtt
    21781 ctgatttgaa agacattcca ttattatttt actgtaatca agccatctgg ctctactgtg
    21841 aattctggct tgtctgccag tgttccgtct ggtttgaggt agtaccagcc tgttccgtcc
    21901 gctgactgga taaaggcatt tgataccatg gcgccttctt tagcgtctaa gtagtaccaa
    21961 gtgtccttgt acttgaccca gcctgtcttc atggcacctt cttcgttgaa atagtaccac
    22021 ttatcagcga ttttcttcca gcctgtagcc atttcgcctg agttgtcgaa ccagtaccag
    22081 ttgccgtctg tgtgcttcct ccagcggtct gcaagcatat agcctgaact gtcaaagtag
    22141 taccaagtgc cattgatttt ctcaaacttg tcttttggat aagagccgtc tgaatgtacg
    22201 taccagtagc cagtgtcatt cttctgccag cctgtttcaa tcgtcaagcc gttctcaata
    22261 tcatacttaa actgctcacg gctaatgccc cattttgcca agtaagggta tggatccaca
    22321 tggtctgagt ggttgtttgg ttggttattc gtgcaatact cgtgcgtttt aattccagct
    22381 aaactccctg tatcaagcgt tttcggcaaa cctgcttcat ctgctagatt gcgtaagagt
    22441 tcgatataaa ggcggtagtc cgtcatgaac tcttctttag ttgaatggct ttcaatcagt
    22501 tcaaccgctg cataggtctc agcattccaa ccgcccccaa cgtcccaggc accattatca
    22561 acaggtccta cctgcatgat gcaaccgttc ccaacaatgt gcgagaaaaa acctaattct
    22621 gggtctttcc gccagtgata atccgcttca ttctgtacgg ttgaatgcgg attcccagtt
    22681 gagtgtgcgt gtacttgcct atatggttgc acgccgactt gaggcaaatc tgttcttaat
    22741 ttactcacat taatttccat attctactcc ttatcaatta aaacaactca ttttttacaa
    22801 tccagaacca gaaactcctt tatttctacc ttacaaagaa gacaatctta gtcacgatta
    22861 ggcttgtaga tagaacctca aaacgcacta ttttgacact gtaaatagga ctgacaaggt
    22921 ctgcattcta tctacaataa caccccagac taaaaagctt ttcaaaagta tatttttaca
    22981 gtctctatat gtccttttca taaatactat actttattat atcatataaa agaagtcaaa
    23041 agtctgttaa actattttca acaccaaact aaagaagaga acacaagttt tttcgatgtt
    23101 cactagagga aatggatttt attcagtaaa tccaactagg attgcacttt ggttgccaaa
    23161 attgcctttc cttcttttat caagggatga cggaatagtg agaagtacag ttgaactgtc
    23221 atggcaaccc agataagagg ttcacaaagg ataacaccct tatatcctgc ccaaggaata
    23281 atcaaaacca caaaaacgat ttttccgatt agttcaataa agctagaaac tagaggaagg
    23341 atcttctgcc ccaagccctg caagcaattg cgataaatca acaagaggct caaaatggga
    23401 taaaaggctg aactgatttg cagatagaga cttccatttt ctatcaagta accatctgtc
    23461 gaactagcca agaaggaaac caaggctgga ctggcaaaaa agaggaaaat acaaacaaaa
    23521 actgcccagg atatacttaa acgactgccg attcgaagac cttgaacaat gcggtcaggt
    23581 cgcttagctc ctagattctg agaagcaaag gtcgtcattg atgcagaaat agcggtcata
    23641 ggaagaaggg caaaggtcat aatgcgtcga gctgccgtct gggcactaat aatcactgca
    23701 ccaaatgtat taacagaaaa ctgtaaaatc acactgccga tagatacaat tgaactcatc
    23761 aagcccatag ccaaaccttg ctccaagaga tccgcgtaca agcttttgtc ccatttgaaa
    23821 tgtttaaacc gtggcaagag ttctggcaca cttttacgaa tataataaaa gcagagaacc
    23881 gctgataaac cttgcgaaat aatggtagca agtcctgcgg attgaactcc cagatgcaat
    23941 tgcgtaataa aatagagatc cagaaccaca ttaaccaagg cagagaaaat cagaaatccc
    24001 agggctgcta gactgtcacc aatagaccgc aacaagcctg caaaaagatt ataagcaaag
    24061 ctgacaccta cacaggtcac aatcatagaa atatattgat aagattgagg aagaatttct
    24121 gcaggagtat ctaagtattg caagagagga tacaagccaa gaaagcccag caacataact
    24181 agaatgctca aaagagcacc taaaatccag gtggctgcta ctgcttcctt gattttagtg
    24241 aaattccgag ccccataata acgagcaatg acaatcccca tgccattgcc aacaccaagt
    24301 gtaaaaccta caatcaggtc aaaaatcgct gtcgtcgctc ctactgcagc caaggattct
    24361 tgaccaagaa atcgtccaac aatcaagaca tcagcagtgt tatagagctg ttgaaaaata
    24421 tttgatagca agattggaaa ggtgaagctt aagagcgagg gaagaatcga accatgtatc
    24481 aggtccactg ttcgtttttt attcataaag ctattatatc agctttccag aggagcgaca
    24541 agaaacagca aacttatata tagcggaatg aaataaggac agtcaaatcg atttttaaca
    24601 atgttttaga aatagatgtg tactattcta gtttcgatct attatagttg gttgagtttg
    24661 gaatagtacg ctgtagctgc taaaacattt ctagaaatta atttgacttt cctaataaag
    24721 ttgttcatat cttatttcaa gctactatat ataatctaaa aacttgaatc aaaaatcgaa
    24781 aaagtagcgg atttttccac tgctttaaca gcttattctt caatttcgat ttcaagttca
    24841 tcgcctaagt caagcgtaac ttcttcattc actgcttctt ctttctttgg ctcatctttt
    24901 ttgttttcag tatcttgttc tgaaacttct tctccatcaa tcaagccaaa tttagaacgg
    24961 acttgcttat caatttcatc aaagatttct gggtgctctg ccaagtattt cttagcattc
    25021 tcagaacctt gcccaatttt ttcatctttg taagaatacc aagcccctgc ttttttgata
    25081 atatccaaat cgcttgcaat cttcaaaagc tcaccagtct tagaaattcc ttctccgtac
    25141 ataatttcaa ctacggcttc cttaaacggt ggagctacct tattttttac aaccttaatc
    25201 ttagtttctt taccgacatt ggtttctttt tggtcaccag ttcccttaat ttgtgtatta
    25261 ccacgaacat ccaagcggac tgaagcatag aatttcaaag cacgtccgcc cggtgttgtt
    25321 tctggatttc caaacatcac tccaactttt tcacgcaatt ggttgataaa aatggcaatt
    25381 gttttggttt tattgataga ggcgccaagt ttacgcatgg cctggctcat catacgagcc
    25441 tgcaaaccaa catggctatc tccgatatct ccatcaattt ccgcacgagg aacaagggca
    25501 gcaactgagt cgactacgac aagatcaact gcacctgagt caatcagttt tcccgcaatt
    25561 tcaagacctt gctctcctga gtctggttga gacaagagca attcgtcaat attgacacca
    25621 agggccgcag cataagctgg atcaagggca tgttccgcat cgataaaggc agcaatccca
    25681 ccttcttttt gcgcttgtgc aactgcatga agggcaaccg ttgtcttacc agatgactct
    25741 gggccataga tttcgatgat acgtccctta ggataaccac ctgagccaag ggcaatgtca
    25801 agagctaaag aacctgagct catcacttgc accttttgct ccgcacgttc acccaaacgc
    25861 atgattgatc ctttaccaaa gtctttctca atcaatttaa gagcgtcatt caaggccttt
    25921 tcacgttctg ccccaaattt ttttgaaatt tcttctaatt tttttggttt tttcgccatt
    25981 ctattctcct acattctaat gatcctcaga cctatctact attatatcaa aagttagtca
    26041 cttaataaag ccttgcgaac taggttaaag gcatgcataa ccgcaatatg acgtacatct
    26101 gctcggcttc tgcctccaat attaaccttg ataacctcag ttccttgctc ttgcgccaag
    26161 cctatgaaga ctgtcccaac tgggtgtcct tctaggctat ctggtcctgc cactccggtc
    26221 aaactaattc caaaatcaga ctgggtcttg cttcgtgcct gctcagccat cttctgagct
    26281 gtaaattcag acaccacacc atgttcttcc aaattcttgg caggaatatc caacatcctt
    26341 gatttttcct ccaagctata ggtcacaaaa ccacccttaa atatacttga aactccagaa
    26401 aaattcgcca cggtagcttg gaaaagacct gccgtcaaac tctctgcagc cgcgatggtt
    26461 ttcccttgcc ttttcagttc ttctaccaca atgctggcta aactagtttc ttccccataa
    26521 ccatagcaaa agtctcgtaa agaaattcct tcgaaagtct ggcagtccaa gatttgattt
    26581 tccaagatat ccagcgcttg attcgcctct tcttgactgc tagcctttgt tgacagacgt
    26641 agagtgactt ctcctgtctt ggcataaggg gccaaggtag gatcgatctg attatcaatt
    26701 aaatcagcca aaatcgtaac caactggctc tcgccaatcc caaagaaacg aagaactcgg
    26761 gaatacagct tgctccctgt catcaacttg ggtagaagtt ggtttaagac catgggtttc
    26821 aattcacttg gcggacctgg aaggacgaca taggtcactc cgtctacttc taattttcct
    26881 ccaacagcca gtcctgtttc gtttggcagt ggaatcgctc cttctacaat ttgagcttgt
    26941 ctttcgttat tcggtgttcg ggcatagtct ggtcgcaggg caaaaaagat atccaacttc
    27001 tcctgagcct gaggatcaaa gactaatgct ttccctaaaa atttagctag ggtttgtttg
    27061 gttaggtcgt cctcagttgg ccccaaaccg cctgtcaaaa tcaccagact gctacgttga
    27121 ctggcaatct caagcaaaga caagagacga acttcattgt ctcctacagc cgtctgaaaa
    27181 tatacatcta ccccaatctc agctagtttt tccgacaaaa actgggcatt ggtgttgaca
    27241 atctgtcctg tcaaaatctc tgttccaaca gcaatgattt ctgctttcat gtttcctcct
    27301 acctatctat tcgtattttt ttgaaaaaat cgcaggaatt ttcctacgat tgattttttt
    27361 atttgtatca aaagttaatt atcttcatca ccaacaggtg ctctgccaaa taaatcttca
    27421 aataaaaccg cattggtttc aagctgagta acttcttctt gtcccaaaga acgtcggagt
    27481 atattttgca tttccaacat atgtgctctc gaaacaatct ggtaagaaac accttgaagt
    27541 atctctcctt caccctgcaa ctgctgagtt tcaatggttt taaatgaatc tttatagcct
    27601 agcaagttag ggatactttt tgcagacaaa tcaatatttg tctgcatatt gtcactcaaa
    27661 gcttttagaa tctcttgata atgaccaatg ctatttaaac tgagagcttt ttccatgact
    27721 ttttgaataa cttcacgttg acgtttttga cgaccataat ccccctcagg atcttggtaa
    27781 cgcattcgtg catagactag ggcttcttct cccccaatat gttgctcccc aacaccgata
    27841 gaaatggtat taaattcttc ttggtcactg atagaaattg ggaaacctag gatattattg
    27901 actgtaatac ctcctactgc atccactagt ttttgcaacc ctctcatatt gaccatcaca
    27961 tagcgatcaa tatggatatt catcattttt tgaatggttt ctatagcaag ctctgctcca
    28021 ccatctgcat atgctgagtt cagtttcgct tcatgagcct gaccattccc tgattcaatg
    28081 cgcgtcagaa tatcccgctc taaactcatc attgttgttt ttttcgtttt aggattcact
    28141 gtcatcaaga tcatgctatc acttctaccg acccaagttt cagttcgttc agcatttccg
    28201 gtgtccactc ccattaacag aatggttaga ggttcagtcg cttcaataac cttggtttct
    28261 tcgccgattt ttttataggt tttagctaag gtttctgtcc cttgttgata aatagtataa
    28321 gcaaaaacac ctactcctac tacagttaca gaaagtaaag ctagcaccat tccaataatt
    28381 tttttaacca tatttctact aatctatcag tttacccatc aagtaaacat cgataaattt
    28441 cccttcttct atatatgccc cacgctcttg gctaccttca atgacaaagc catgcttttg
    28501 ataaagatgg actgctgctt gattacgagt ttggacagtc agttggagac gacgcagaat
    28561 gccacttgct tgtgcccact ctatcgcttc ttctagcaac aaacttccca agccattatt
    28621 ccaatatctt tttccaatca caatgaagag atctccaata tgacggactc tcttacgctg
    28681 atcagctgta atatttacaa taccagcaat tttgccattt aagaatgcaa gtaaggttat
    28741 ctgattgtcc gaactagctt gcttgttgag gaatatttcc atctcctcac tagtcaagag
    28801 aataccatct ccgtctaggc tggtaaagtc tgtctccaaa ctcacacgat ttaaaaaggc
    28861 cactaattca gctgcatctt tgggctctgc ttccctaatg agcaattcat actccatatt
    28921 gaagctcctc taacaatttc tcagcacgca aaccctttgc ctgaaaattt aaacggcgtc
    28981 catctgcttc ttttagaatt tccaattcta aataagcatc tggcaaggca tctcctaaga
    29041 gatttcccca ctcaataaca gtcacgccgc caccaaagat aaactcatcc aagtcgatag
    29101 aatcagcatc tccttcaata cgataaacat ctaggtgata aagtggaagt cgaccttcat
    29161 actctctcac gatagtatag gtgggacttt taatcatttg agaaatctgt aatccttttg
    29221 caagtccttt agtaaaggtc gttttacctg cacccagttc tccagttaag attaaaacat
    29281 cattctttgc taatagatgg cccaaacgct cccctaaggc ttgcaactct tcttcatttt
    29341 ttgtgtacat actcttatta taccaaaaac ttttcttttg tgtctatttt cctactaaac
    29401 ttatcatcat aacatccata caaaaacagg ctttctctaa aagaaaatga gcgtaacaat
    29461 gaccaataca agatctcgga aaatatgacc ataaaaggaa acttccttct taaccgaatt
    29521 tgggacaaga taggctgcaa aaaacaagcc cagtccaata taaatcagaa gtgagacaat
    29581 ggtcattgga tttcttaaga aaagaagtgt tgctaaaata gtcaccaaca ctgtcttttt
    29641 tctgtctagc atagcaagaa aatcgcgcac gtattttttc aagggtaaaa aaatcagcaa
    29701 atctagccca aataggaaaa agaaggatgg caataaaaag tcaactaatt cttgctgcag
    29761 cgtatttttg atgaacaagt tatctgacaa aacaagaaca gctcctaaca aattaattaa
    29821 gagtaacata ctgtaaaaaa gcttcaccga cttcttactg gctaggacac tatggacttc
    29881 ttgcttacgg gtataaagat aatttactcc agcacagatt cctgaaacga aaaccatgct
    29941 tccgatgaaa aaagctgtac tttgtttaaa ggacaagatg cattccttcc ataagaaaca
    30001 gctactcaaa ctgatttgaa ttaaagctaa caaaaataag attctcattg atttcatctt
    30061 ctctctccct tcctaccaat cattatacta ggagaaaaga gagaactgtt tctaatcttc
    30121 tcaaatgtct ctttaagacg ctaaacaaac actagagact aatactcaat gaaaatcaaa
    30181 gatcaaacta ggtagctagc cacaggttgc tcaaaacact gttttgagat tgcagataga
    30241 gctgacgtga tttgaagaga ttttcgaaga atataaattt gaaatcatga aaatccgtca
    30301 aacgggtggt tgttttgtct cgcacctcac ggagcgagac ggactcagag tcacataatt
    30361 ataaggctga tagtattaat ctaactatca gccttacagg ttatttaacg tttcagaaaa
    30421 actataatgt caagattaac taaacagtat ctagttcctt caaataattt tctatcttca
    30481 tcaacattaa aggattgtta taaatcttac ataactctct tgcttctata taataatttt
    30541 tgacttgttc tctgtctaga aatttggcgc cagcatttcc tacaagaata agtagaggag
    30601 ccaattggta gcttgtctgt ctttgtttac agagttcaat cgtttcaaga gcttcttgga
    30661 tggcttcatt atatttttcc tttgatacta ggtagtgagc gtagttgtaa cgaactctga
    30721 tgtagccaaa taaaaactct tgatggtcca aattttttgt ctgatacaac tctattaaat
    30781 gagagtagtt tgcctcatat tcttgttcac gacccactaa ggaatagaaa ttagatagag
    30841 tattcaacgc ctttaaataa atcagagtat ttgaagagac ttttaataat atattttcca
    30901 atgaagaaat tgcctcacac ttactgtcat attgatagaa gtcaataata gctttaatcc
    30961 attcaaggta agttcggtct tctagtgtta gaaaagtact tcgttcaatc tctattctat
    31021 aaatatattc caaatcgtca taatttctat cgtctaatag tcgagcagac aattgcttga
    31081 aattagagag gttagattta atttcaattt gttcattaaa aaaataatct aatggtactt
    31141 caagtcgttg agagagtttg aacaaaaggt ctgcggaggg aatgaaatgc cctctctcaa
    31201 ttttactaat ctggctttgt tcacaaattc cttctgcaag agtttgttgg gagagtctca
    31261 actcttttct tttcaatctg aatttctctg cgagtgtact cattaaagat aataaacctt
    31321 cctatttgct taattgcatt ataaaatttt tagttcaaaa tagcaagtta aagaaataaa
    31381 taattcttta tggtaataaa ctaaaaaaag tcaaaaatta cataaaaatg cttgaccgaa
    31441 taatatatat atattaaaat aaaaacaagg aaaaagaaag gggtttcatt gcatgagaaa
    31501 aaaacgtgga attaaaaaat tagttacatt tgatgcggga tggtaaagaa taattgaaga
    31561 agattctttt atcaatagtt tagtaagctt gttagtttat agagggcagg ggtatttctg
    31621 ccctctgttt tagaataagg aatgcactat gaaaaaatta tttatactca tatccaacct
    31681 gcttgctagt ttgttctttg tttgggtatt taccatttgg actgatacat atgtctccca
    31741 ttattacccc aacgttgttg tacgtgattc ttcccctgaa acaacttttc agcatgttgc
    31801 tacacgcttg gaaaaactag cagaagaaac agatagcttt attgcgattc aacaccaaga
    31861 tcctaactca gaaggtacta cagttttttc ttatacgacc tttggggacg gaaagttgcc
    31921 tgatgggctt caggaaaaaa atctagaaga tgctcaaagt agtagtgttg aaacaaacta
    31981 ttttgtattc gatggacacc tagatattca cttgctaagg gaagagctaa gtcaacttgg
    32041 cttgactaac atgcacctga caattccatc taaactatct acgttaatgg ctatctttag
    32101 taacggattt cagttaatca gtctattgat tttcatctta acctttgtag cactgacttt
    32161 aattagtcaa attagccaat tacggtcatc gggcattcgc ctcatttcag gagagaaacg
    32221 gtggttcatt ttccttagac cagttggtga ggatttgaaa gcgatagctg ttggtttcag
    32281 tttagctggc gtgctcgcca ttcttatgca aaaaattctg tcgcttccaa cgcaatccct
    32341 aatgaccata ggagaaggct tgctcagtta taatctcatc ttgttgtcga tctccctgtt
    32401 tttcgctcaa ctcttcgcag ttgggataaa aaagatacac ctgatgcaga ttataaaagg
    32461 gcaagtgcct gtcagaggaa tcattagttt gattttaatc ggtcaactat tagcgattat
    32521 tattgtaacg ctgggaatag ggagtagctt aaagtattcc caagcctggc aacagcatcg
    32581 gattggacaa gaggcttgga gtcaggaaag acaactgatt accctatcaa tcagccgtga
    32641 aggaacgagt cctggttttg atgaacaagc tcaaaggaaa ctcagaactt ggtatcaatt
    32701 gatggatctg gctgtttcag aacaaaaggc tttcttatct agacaccagt taattgaccg
    32761 tactttgcaa aatggcatgg cttcctccaa aaacttgata acctctacag aatggcacga
    32821 ttacaacccg aatggcaatg tccttatcgt cacaccgcaa tacttggagc gtcaaaacat
    32881 tcctgtagat acaactattg agcaaaagat gaatcacctt aatgtagggg agtttgtctt
    32941 attgctgcct gaacacctcc gttcagagga agaacattat aaatctgttt ttgaagacga
    33001 cttaaccagt cgcatgtcta gtcaagatga acgacagcaa atgactgcta cggtaggtta
    33061 tttagaatca ggtcaggatc gttttgtgta taatacgacc cctatttctt accagcagtt
    33121 tttgaaagat ccaatcatca ttgttataac accccaatca actggtccac agtccatttt
    33181 gttttggata gacgcagtac agaactacgt tctctttaat caattgtctg atgcccagga
    33241 gcttatccag agacaaggca ttgaaaattg ggtctcagaa atgcaaacag gttaccacaa
    33301 ctacatcaca ttattggata atatccagag ggaacgttgg gtaatgctag caggagctgt
    33361 gcttgggatt gcaacttcaa tcttgttgtt taacactatg aataggctct actttgaaga
    33421 atttagacgt gccattttta tcaaacgcat tgcaggtctc aggttcttag aaatccatcg
    33481 cacttatctc tttgctcaac tgggtgtgtt tttactggga tttgttgcga gtgtatttct
    33541 tcaggtagag ataggagttg ctttcttagt cttgttactc tttactggtc tatctctttt
    33601 acagttacat gtccaaatgc agaaagaaaa caagatgtcc attcttgttt tgaagggagg
    33661 ttaatatgat tgaacttaaa caggtgagta aatcttttgg agaacgagag ttattttcga
    33721 atctttcaat gacatttgag gctggaaaag tctatgcctt aattggttca agtggtagcg
    33781 gaaaaacaac cttgatgaac atgattggga aattagaacc ttatgatggg acgatttttt
    33841 accgaggtaa agacttggcc aattataaat cgagtgattt tttccgtcac gaattgggct
    33901 acctcttcca gaactttggc ttaattgaaa accaaagtat tgaagaaaac cttaagctag
    33961 gtctcattgg ccaaaagttg agtcggtcgg aacagcggtt gaggcagaag caggctttag
    34021 aacaggtcgg cctggcttat cttgacctag ataagcgcat ctttgagtta tcgggcggag
    34081 aatcgcaacg ggttgccttg gcaaaaatta tcttaaagaa tccacccttt attctggcag
    34141 atgagccaac agcttcaata gacccagcaa cctctcagtt gattatggag attttgctat
    34201 ctcttcgaga tgataatagg ctaatcatta tcgcaacaca taatccggca atttgggaga
    34261 tggctgatga agtgttcacg atggatcatc tgaaataaaa atccttgttt ttaattgcac
    34321 gatgagttac tgaaatatta tcatgaatca ataattggag ttaatttaga attgtacttt
    34381 attaatattg aggtaacttt ttcttgataa aggaggaaat agtggagagg aagttagaat
    34441 gaaaaaattc gacaattata ttattgagaa gccttgcgat tctaattcag ataaactgca
    34501 aaaaatctta ataattgaaa atttgggatt gaaaatttgg tagatgatat tttgcaattt
    34561 cctctcagaa tcaataatag tgtaggagag attttcctcc tacaaccgtt ttaaaagaaa
    34621 actatcttta ttccatgtta ttttgaggaa gatattgtga aagtcaaaga tgatgataaa
    34681 gttgagtgga atttgttaga atttcaaaaa tttagagcat ttttggctta gtaatctgtg
    34741 ttgaaggctc aaaacctatg gtaaaaaagt agctttgaaa acgtattgcc tccaaagatt
    34801 tagttaaata atgatttaac acaaaaagaa attattgaag ttctggaaag atgttgtttc
    34861 agtattgaga aaaggtggga aaaacttgcg attttcacag agaaaggaag aaaaagtata
    34921 gaaatatagt caattgaaac aagaacagga taaaagaacc ttttgtgcca tatttttctc
    34981 ctttcgcttt acaattggat tgaacacctt tattgtatcg cgtttggagt ttttttggta
    35041 taaccttcga cgcacacccg catagcgggt gttttttttg tctcgcacct aacggagcga
    35101 gacaaactaa tagtcactta atcaaaaaac gcaccatatc aaaaactaaa aagtttgata
    35161 tcatgcgtca tgtcttaaac taattgacta tactttctat tcaaatgagc ttttaaccaa
    35221 ttgattgagc caatccactc ttaaaaccaa agagcaattt ctcgcttagc tgactcttct
    35281 gaatctgaac catgtacaac attttggata atctcatttt ctccagcagc ttttgcaaaa
    35341 tcacctcgaa tagtgcctgg taaagcttct tctggacgag ttgcacccat catggtccgc
    35401 caagtttcga ttactttggg accagaaatg acacccacaa gaactggacc tgaagtcatg
    35461 aattcacgaa tcggtgggta aaaactctga ccaaccaagt cctgatagtg ctggtcaatc
    35521 aactcttctg aaacctgtga acgaaactcc aatttttcga ttgtaaatcc acgttgttcg
    35581 atgcgcttta acacttcacc cactagccct ctttttacac catctggttt gatgataaag
    35641 aatgtttgtt ccatacccgt ctcctttgtc agcttctttc ttttatttta ccacatttcg
    35701 tggaaaaatg gagaaagttt tcagaagaga gaatgagaga accctcgggt tctctcattc
    35761 tctcttattc tactgtttct tccacagttt caacggcagt atccacaact acttctgttg
    35821 tttcttcatt tccttcttcc tctactggag gattaaggta ttcttcttcg ttgacagcat
    35881 gtggttcaag gttacggtaa cgggccatac cagtaccagc tgggatgatc ttaccgatga
    35941 taacattttc tttaagtcca aggagatgat ctttcttacc acggatagct gcgtcagtaa
    36001 ggacacgagt tgtttcctgg aaggaagccg ctgacaagaa actgtttgtt tcaagtgagg
    36061 ctttggtaat tcccataagg actgggcgac ctgtcgctgg aactccacct gcgataagga
    36121 catctttgtt ggcatctgta aagtcattga tatccatgag ggtacccatg agaagatctg
    36181 tatcacctgg atccatgaca cggactttac ggatcatttg acgaaccatt acctcgatgt
    36241 gtttgtcacc gatttctacc ccttggctac ggtaaacttt ttgtacttca ccgagaaggt
    36301 acgtttcaac tgacaagaca tcacgaactg caaggagacg ttttggttgg atagaacctt
    36361 ctgtcagagc agcaccacgc gctacttggc ccccaacttc gacacgcata cgagctgtaa
    36421 atggaacgac atattcacct tcgccagttt cacccttaac aaagactttc ttggtacgag
    36481 ttgatgcatc ttcttcgata gcagtaactt gtcctttaac ctctgtaata accgcttccc
    36541 ctttaggatt gcgggcttca aagatttctt ggacacgagg aagaccctga gtgatatcgg
    36601 tatttgaggc aaccccacct gtgtggaagg tacgcattgt aagctgtgta ccaggttccc
    36661 cgatagattg ggcagcgatt gtaccaactg cttcaccaac ttcaaccgca tcaccagtcg
    36721 ccaagttgat accgtaacag tgacggcaga caccgtgacg agtgttacat gtaaatacag
    36781 aacggatagt cacttcttcc acaccagcat tgacaatttc acgcgccttg tcttctgtaa
    36841 tcaattcatt tggaccaata atcactgcac cagtttctgg atgtttaaca gttttcttag
    36901 tgtaacgacc gttgagacgc tcttcgagag actcgatcat ctcttttcct tctgcgatag
    36961 aacggatcaa gagaccacgg tcagttccac agtcgtcctc acggatgata acgtcttggg
    37021 caacgtcgac caaacgacga gtcaagtaac ctgagtcggc tgtcttaagg gccgtatcgg
    37081 tcataccttt acgagcaccg tgagttgaga agaacatttc caataccgac aaaccttcgc
    37141 ggaagtttga aaggattggc aattccatga tacgtccatt cggagcagcc atcagaccac
    37201 gcataccggc aagctgtgag aagtttgaga tgttaccacg ggctccagag tccatcatca
    37261 taacgattgg gttcttagga tcttggttag caatcaagcg tttctcaagt ttttcacggg
    37321 cagcacgcca ttcagctgta acagcattgt aacgctcgtc gtctgtgatc ataccacgac
    37381 ggaattgttt ggtgatttgt tcgacacgtt tgtgtgattc ttcaatgatt tcagccttgt
    37441 catcaacgac tgggatatcg gcaataccca ctgtcaatcc tgcaagagtt gagtggtggt
    37501 aaccgaggtt cttcatgcgg tcaagtaggg cagaagtttc tgtcgtacgg aaacgtttga
    37561 agatttcagc gatgatattt ccaaggtttt tcttcttgaa tggagggttg agctcaagat
    37621 tgctgatagc ttccttgata tctccaccaa gtggcaagaa gtatttagct ggaacacctt
    37681 ctgtcaagtt ggcattgttt ggttcttgca agtatggtag cccctctggc atgatatcgt
    37741 tgaagagaat tttaccaact gttgtaagca agaccttatg tctttgctct tctgtccaag
    37801 gcttgttgag gctgtctgtt gcgataccaa cacgtgagtg gaggtgaaca taaccattgc
    37861 ggtaagccat aaccgcttcg tcacggtctt tgaagaccat tccttcacct tcgcgaccag
    37921 cttcttccat ggtcaagtag tagttaccca aaaccatgtc ctgagatgga gtaactaccg
    37981 gtttcccatc tttcgggttc aagatgtgct cagcagctag catgaggata cgagcttctg
    38041 cttgtgcttc ttctgaaagt ggtacgtgga tggccatttg gtccccgtca aagtcagcat
    38101 tgtaggcttc acagacaagt gggtgcaagc gaagagcctt accatcaatc aagactggct
    38161 cgaaggcttg gatacccaaa cggtgaaggg tcggtgcgcg gttcaaaagc actgggtgtt
    38221 ctttaatcac ttcttcaagg atatcccaga tacgctcatc tccgcgttcc accaagcgtt
    38281 tagctgcttt gacgttttgc acgatatcac gggcaacgat ttcacgcatg acaaatggtt
    38341 taaagagttc aatcgccatt tcacgcggca caccacattg gtacatctta agagttggac
    38401 caacggcgat aacggaacgt cctgagaagt caacacgttt accgagcaag ttttgacgga
    38461 agcgtccctg tttaccttta agcatgtggc tcaatgattt caatggacgg ctacctggtc
    38521 ctgtgattgg acgaccacga cgaccattgt caatcaaagc gtcaactgct tcttgaagca
    38581 tacgcttctc attttgaacg atgatacctg gtgcatttaa ctcaagcaaa cgagccaaac
    38641 ggttgttacg gttgataaca cggcggtaaa ggtcattcaa gtcagatgag gcaaaacggc
    38701 caccatccaa ctgcaacatt ggacgaagat ctggtgggat aaccggaagg atgttaagaa
    38761 tcatccattc aggtttgttt ccagacttgt aaaaggcatc caaaacatcc aaacgacgga
    38821 tggctttgac acgtttttgt ccagtagctg ttttcaattc ttctttgagt tcagcaattt
    38881 ctttttcaag atctacttgc ttcaaaaggt cttggatggc ttccgcaccc atcttggcaa
    38941 caaatgaacc ataaccatat tcacgcaagc gctctcggta ttcgcgctct gtcatgatag
    39001 acttgtgctc aagtggtgta tccttaggat caatcaccac ataagccgca aagtagataa
    39061 cttcctcgag ggcacgaggg ctcatatcaa gggtcaagcc catacggctt ggaatcccct
    39121 tgaagtacca gatgtgagat acaggagctt tcaattcgat atgtcccata cgctcacgac
    39181 gaactttcgt acgcgttact tcaaccccac agcggtcaca aacaattcct ctgtaacgaa
    39241 tgcgtctgta cttaccacaa gcacattccc agtcttttgt aggaccaaag atcacttcat
    39301 caaagagtcc ttcacgttct ggtttcaagg tacgataatt gattgtttca ggttttttga
    39361 cttctccata agaccatgaa cggactttac ttggagaagc tagggtgatt tgcatacttt
    39421 taaaacgatt tacatcaacc actatttctt ccctttctat tctaagtgaa ctgcttattc
    39481 ttgttcagca gcttcttctg ttgcttccgc ttttgttgct ttctcagctt cttcagcttc
    39541 aaaggctgct ttagcctctt gggctgcttt ttcgcgggct ttttcaaggt catctacgtg
    39601 gatgacatct tcgtccattc cttcatccaa gtcgcgaagt tccacttctt ggtcatcttc
    39661 gtctaggaca cgcatgtcaa gaccaagaga ttgcaattct ttgacaagaa ctcggaagga
    39721 ttctggaaca cctggttttg gaattggttt gccttttgta atagcttcat aggctttcaa
    39781 acgtccgttg atatcgtccg acttgtaagt caagatttct tgaaggacat ttgacgcacc
    39841 gtaggcttca agagcccaaa cctccatctc accgaaacgt tgtccaccaa actgagcttt
    39901 acctccgagt ggttgttggg taacagttga gtaaggtccg actgaacgcg catgcaattt
    39961 atcgtcaacc atgtggtgga gtttgatcat gtacatgact ccaacagaaa cacggttatc
    40021 aaatggttca cctgtacgtc catcgtaaag gattgtcttg gcatcgctat ccatacctgc
    40081 ttctttaaca gttgaccaaa gatcttcaga acttgctcca tcaaagactg gtgtcgcaat
    40141 gtgaatacca agagtacgag ctgccatacc aaggtgaagc tccataacct gaccgatatt
    40201 catacgtgat ggcaccccaa gtgggttcaa catgatgtcg actggagttc cgtctggaag
    40261 gtaaggcatg tcttctacag gaacgatacg agagacaacc cctttgtttc cgtgacgtcc
    40321 ggccatttta tctccgacct taatcttacg tttttgagcg atgtaaacac gaaccaacat
    40381 gttaacacct gattgcaact catctccatt tacacgtgta aagatcttaa catcacgaac
    40441 gacaccatcg gcaccgtgtg gtacacgaag agaagtatca cgcacttcac gagacttgtc
    40501 tccaaagata gcgtgcaaga gacgttcttc agctgaaaga tctttctcac ccttaggtgt
    40561 tactttacct acaagaatat caccttcttt aacctcagca ccaatacgga taatccccat
    40621 ttcgtcaagg tctttgaggg catcttcacc aacgtttgga atttcacgag tgatttcttc
    40681 aggcccaagc tttgtatcgc gcgtttctga ttcgtattct tcaaggtgaa cagatgtgta
    40741 gacatcgtcc ttcaccaagc gttcgctcat gataacggca tcctcgaagt tgtaaccttc
    40801 ccaagtcatg taggcaacga ttgggttttg tccaagcgcc atttctccat tttccataga
    40861 aggtccgtca gcgatgaaat cgcctttttc aacgacatca ccaactttta cgagagtgcg
    40921 ttggttgtaa gcagtacctg agtttgaacg acggaatttt tggatgtggt aaacatccaa
    40981 tgaaccatct tcacgacgaa cttctacctt gtcagcatct gcgtaagtaa ctttaccatc
    41041 atactgagca atcacagccg caccagaatc gtgggctgct tggtattcca taccagtacc
    41101 aacgtaaggt gcctgaggat taatcaatgg cacagcctga cgttgcatat tggctcccat
    41161 gagggcacgg ttggagtcat cgttttctaa gaaaggaata catgctgtcg caacggcaac
    41221 tacctgtttt ggtgaaacgt ccatgtagtc aacaatatta gctggatact cttggttgac
    41281 cccttggtga cgtcccatga caatcttctc agcaaaggtt ccatcttcat tcagacgaga
    41341 gttagcctga gctacagtat attcatcttc ttcatcagct gtcaaccaaa caatttcgtt
    41401 cgtgacaaca cctgtttcac ggtcaacctt acggtatggt gtttgaacaa aaccatattt
    41461 gttcaagtgt ccgtaagatg acaagttatt gatcaaaccg atgttaggtc cttcaggtgt
    41521 ctcgattgga cacatacgac catagtgagt gtagtgcacg tcacgtactt catatccggc
    41581 acggtcacga gtcaaaccac caggtcctaa ggctgacaaa cggcgtttgt gagacaactc
    41641 agaaagcggg ttgtgttggt ccatgaactg tgacaactgt gatgaaccaa agaattcttt
    41701 aactgcagct gttacaggac ggatattgat aatttgttgt ggtgtcaaga cttcattgtc
    41761 ctgaacagac atacgttcac ggacattacg ttccatacga gaaagtccca aacgtacttg
    41821 gttggcaagc aattcaccaa ccgcacggat acgacgattt ccaaggtggt cgatatcatc
    41881 tacacggcca agtccttcag ccaagttgag gaagtagctc atctcagcaa ggatatctgc
    41941 aggagtcacc gtacgaacct tgtcatctgg gttagcatta ccaatgatcg ttacgacgcg
    42001 atctggatca gttggagcaa caaccttgaa tttttgaaga acaacaggct cagtcacaac
    42061 ggctgcatcg tttgggatgt agacaatctt gttcaagtcg ccatccaaat ggctttcaat
    42121 gctttcaatc acgctacgag tcataatcgt accagcttct accaagattt ctccagtttc
    42181 agggtctacc aatggctctg caatggtttg gttgagcaaa cgtgttttaa cattgagttt
    42241 tttattgatt ttgtaacgac caactgctgc caagtcatag cgacgtgggt caaagaagcg
    42301 agccacaagc aagctacgtg agctttcagc cgtcttaggc tcacctggac gaaggcgttc
    42361 gtaaatttct ttcaaggctt cgtctgtacg agagtccatt ggattcttgt ggatatcttt
    42421 ttcaacagtg ttgcgaacca attcgctgtc accaaagata tcaaagattt catcatcacc
    42481 tgagaaacca agagcacgaa ccaaggttgt aaatggaatc ttacgagtac ggtcgatacg
    42541 agtgtaggtg atatcttttg agtcgctttc aagttccaac caagctccac ggttagggat
    42601 aacagttgaa ccatagccca ccttaccatt tttgtctact ttgtcgttaa agtaaacacc
    42661 tggtgagcgg accaactgag aaacgataat acgttcacca ccattgatga tgaaagtacc
    42721 catttctgtc atgattggga aatcaccaaa gaaaacttct tgggtcttga tttcgcctgt
    42781 ttctttattg atcaaacgga aggttacaaa aattggtgct gagtagctag catcgtggat
    42841 acgagcttct tctagcgtgt attttggttc cttgatttca tatccaacaa attccaactc
    42901 cattgtgtct gtgaagtttg aaattggcaa tacatcttca aacacttcct taagaccgtg
    42961 gtctaggaaa gctttgaatg agtcagtttg aatttcaatc aaatttggta agtcaagaac
    43021 ttctttgatt cttgaaaaac tacgacgggt acgatgtttc ccgtattgaa cgtcatgtcc
    43081 tgccaagatg attctccttt gtaaataagt tccaagcctt gtcaatcagg cttttctaat
    43141 cgtcatatgg ttgtaaaccc cttatcaccg tgtcctcttg acgatttttc agaatcttta
    43201 agcctctgtt acaaatgctc aaaatcttga aaaaaagcac aaaaagagca gctaaatctg
    43261 actttttcag aagatttaac tgctgtgagc cttgtctgga caatatttca gacaaaacct
    43321 acgacaaatg attacccata ttatacccta tttagctaga tttttcaagg ggtttcagta
    43381 ggttttttgt aaattttttc ccatagaaaa cttggcatca cattcgaatc acgctatggt
    43441 acaaaaaact gaaaaaacta ttgactgaaa atcattttca aggtataata ataaacgtta
    43501 aggcggtata gccaagtggt aaggcacggc tctgcaaaag cttgatcgtc ggttcaaatc
    43561 cgtctaccgc cttctataac ttgatttatc aggtttcaaa tgaacagaaa gcccaatttg
    43621 aagggctttt cttattttcc ctcgaataaa tacgtataac tttaaaaact tttggagcga
    43681 gtttgtggca gagttctttc catggcataa ttcccttttg aaatcaattg aaaaaagctt
    43741 cgtcacgcct ggtgacaaaa gcctctagtt tattctgttt cttcttctat ttcgacttct
    43801 gtgatttgga cttttacctt ggtaacacgt ccattcttca ctttatcatt ggttaagata
    43861 aactgtttgt tttggctgac caattcatag ctgagtttct cagtcgttgg aatggttccc
    43921 actcctgtca aataataacc agcgatagta tcaacgtcat cactttccag ttcaacatta
    43981 aagtaattat tgaaatcatt gagggtcata gttccttgaa caatgtaggt atcctcgcca
    44041 atctgatgaa catctattgc tgctttgtcc gtttcatcat caatttcacc aacaatttcc
    44101 tctaagaggt cttccaaagt caccaaacca gccataccac cgtattcatc cagcaagatt
    44161 gccatttgtc tttgggtatt tcgcagttct tttagcaagt catccacaaa aatagtttca
    44221 ggtacaaaaa gtggatcttg taaaattctc ttccaaacaa tattgtcaaa accgtccaca
    44281 aagcctgcct taaggagact cttggtgtga atgattccaa ttacattgtc cttatcccca
    44341 tcataaaccg ggatacgaga ataattttgt tttaaaatac tttggataat ggcttgacta
    44401 tcatcctgaa tatccaccat aaaggcatcc gttcgaggaa ccataacctc tcgtgccatc
    44461 agttcatcga gcgaaaagac accttgtagc atctcaatct catcagcatc caatgtttct
    44521 tcactatttg tcagcatata ggcaatttca tcacgggtca tcttttcatc cgcatcatcg
    44581 aatgacatag gagtcaaatg gctcaagaaa ttggtcgaag cagctaaaag ccaaacaaaa
    44641 ggactgacta gttttccgat cccaatgata accggcgctg tacgaattgc caaggcatcc
    44701 tttagattaa gagcgattct cttaggatat aattccccaa aaacgatgga aatataggtc
    44761 aaaaatgcca aggatagaaa agttgccacg gcttgtgctg tttcgccatt cccaagccaa
    44821 gaggcaatca cacgtcctag agtatcagtt aaactcgccc ctgataagat tgtaatcagg
    44881 gtgattccta cctgaatggt tgataaaaag tggttaggat tttctagtac cttcagcagg
    44941 cggatgtagc gtctgtctcc ttcttccgcc ttttgttcaa ctcgggcacg attaagagaa
    45001 accatggcca tttctgtggc tgagaaaaag gcatttaata ccgtcaagat aaacaataaa
    45061 acaaattgta gcaacaaatt ctgactactt gggtcttcca tagttcttct cctaaaatag
    45121 tatcttatcc tttattatat cacaaaattt aatccaatac atattatttt tttcttagcg
    45181 taacttccat ctctctccca aaactggaag ttagtctaag acggatttcc actgatttca
    45241 cgcgtttttc tcatactaaa agctaggttg tgggaaactg gaagttagtt ttagaagtta
    45301 ctattttttc ttagtacctg ttctagccct gcttaaacta gtaaaaagaa ctcctacatc
    45361 cataagtgac ataggagttt aggcttatct tttactgagt tacagttact tctccagttc
    45421 ggtaatccag ttgaagtccc ttttgaacat tgggaactag aacattgaat tccaattctc
    45481 catccgaaga cttggcttca atctgtgaag ctgagggaac taaatcctcg tttgaagcgt
    45541 agtaaagggt tacacggtaa cggacacgct tgttttggtc caaggcttta cgcaccttgc
    45601 tttcatagta gttttgacca gtcgaatact cggcttgtgc ctgatttgcc caggctgtct
    45661 gaacagcaat gtttttagga ttgcttgttg aggcatcaaa accatccaaa ccaccgatta
    45721 aggcatagcc taacaaatga cctctatcga ctgcatgggt ataagagccc tttagattct
    45781 tgacctgatg ccaacctgga ggagtccaag aagttgaacc attcccagtt tctttacgat
    45841 tcttgtactg acgagtggcc ttagacaaga gggcattagc tacggttgga acagtttcct
    45901 tgcccactgt ctttgtttta ttgtcagcgt agggcttact tgaaaccttg gcatctagat
    45961 ttgttttatt accattgacg ataaaagcac ctgagccatt ccactccaga ctccccttta
    46021 tttgactctt gactgcgtct gttaagacac tctctgccaa tgcttgacta ggagcttcag
    46081 acgcttgttt tttctgatta agcttggttt taggactatt agctgtcgac tgcatctgct
    46141 tgatataata gctccctgta gacaaaagca ataacactag cagtccgatt agtgtctgtc
    46201 ttgttttttt gttcatattt ctccttatct ttagaaaaag gctggttctc cagcctaatt
    46261 tcctgtaaat ttatgaatca attcctgcca ttttgctgga gacaggatag cccatggatc
    46321 ttgacccttg cccaagattc cataacctac cattaaaccg attcctagag ccagagtacc
    46381 taaaatcagt actatgatga ctaaaagtaa acgcttgact acgtagcttg atttcttatt
    46441 catcttcatc acttgcctca atccgctgaa tcttagcacc tagctgcgcc aacttctcat
    46501 ggaaaccgta gtaacctcta tccaagtgaa ccaatttacc gaccacagtt tctccctgtg
    46561 ctaccaaacc tgtcaaaatc aaggctgcac tggcacgaag gtcagttgaa agaacttctg
    46621 ctccctgcaa aggctgtcca ccaacaatac gagctgtatc acggataatc tcagaatgca
    46681 agcccatgcg gcgcatctct tctaggtgtt ggaaacgatt ttcgaaaact gtctccacca
    46741 tggttgattc gccttttgca actgtcatca aggctgtaaa ttgagcctgc atatctgttg
    46801 gaaatcctgg gtggggcaag gttttcacat gaacagcttt tagattttct agttgagaac
    46861 gaacacgaat tccttcgtct tcttcaatta cttcaacacc catttcaagt aacttggcaa
    46921 tcaagggacg gttgtgctcc cagacagcgt ctcgaatcaa gacatcacca ccagtcatgg
    46981 cagcagctac cataaaggtt cctgcttcga tacggtcttg gactacattg tgagtcgtac
    47041 catgaagttt ctcaacacca gtaatggtta tagtctctgt accagcacct ttgaccttgg
    47101 ctcccatttc attaaggaga atggctaagt caacaatctc aggctcacgc gcagcattct
    47161 caatcactgt caccccatca gccagagtcg ctgccatcat caagttctgc gttgcaccaa
    47221 cacttggaaa gtccatatag atatgagcgc catgcaagcg ttctgccttg gcttcgatgt
    47281 aaccagctgt ctgactaatc ttaaccccca tagcttccag acctttcaaa tgaagatcaa
    47341 taggacggct accaatcgta caaccacctg gcatggatac cttggcatga cccacacggg
    47401 caaggattgg ccctaataca acgatggagg cgcgcatctt gctgacatac ttgtaagggg
    47461 cttcctcagt gatgtcgcca gtagcatcca ccttgacaag atgagcttcc tcatcaaagt
    47521 caaccttggc attcaaacca ccaactacct gattcataat aaagacatcc gacaaaatcg
    47581 gaacattctg caagacggtc tttccttcac ttgctagaat agtcgctgcc aacaagggta
    47641 agactgcatt ttttgctccc tcgatcgtca cgcttcctac cagacgatta tcgccacctt
    47701 gaaccacaat tttatccata ctcgtttcct ttactcttga ttttataata atcctccaag
    47761 cgcttcttgc cacaaatgat acaggctaat aaagaaagaa ctcaggatgt agcctatgac
    47821 aatgctaaaa aaggctacta ataaacgaac ttttcttgta ttatcatctg tcacttttaa
    47881 aaccttctcc catctaacaa gatcctttaa aaggtaaaaa ctcacataaa taaagaacat
    47941 atgactactt agagtgaata ataattgaac catttgacta ttataccatc ttctctgttt
    48001 gtgcgctagt ttggaaactt cactcaaaaa ttagggattg tttttcaagt aatcaatcgc
    48061 atcttgtagg gttttaacgg gcacgatttt catatccgtc ttgattgttt tagccgcttc
    48121 tagggctgtt tggtagttgt ttttcgcgtc cggatgcgcc ttttgttctt cttcgctaac
    48181 agggttatca ggagcaaaga aaatagcagc acctgcccta gccgaagcta caaccttctt
    48241 atcaatacct ccaatgtctc ccacattacc atcgcggtca atggtacctg taccggcaac
    48301 aatacgacca ttacgaagat ctgggtgagc tatttgagta tagatagcta gactaaacat
    48361 gagaccagca cttggaccgc caataccagc tgttgaaaag ctaattggga cattgctgat
    48421 tacctctgta cggtcaatca agccgattcc aattccattt ttgccatttt ccaaggtgat
    48481 gatttttcct tctgcagact tggtttgccc atcctcttca taggtgacct tgacggaatc
    48541 ccctaatttt tgagaactga cgtaatcaat caagtctttg gaactatcaa aggtctgatc
    48601 attgactgct gtgaccgtat cagagatatt gagaatccct ttaaaggttg aattatccgt
    48661 cacattcaaa acataaactc caaagtactt gagttcgata tccttaccag ctgtttttag
    48721 tccttgatac ttggccatat tttgcgatgt ttgcatgtag aattgattga ttcgcataaa
    48781 ttcaacatcg gaagaaccac ctgtagtctc ctgagcacta cgaatatctg taaaaggtgt
    48841 caaccaagca taaatcatat gagctaaagt ggcatgttga acaccaaccg taacgaattg
    48901 ataggcacca gcttccttat cttctgtgtc atttacttta aggacttggc gaatatcttc
    48961 cgaaccacct ggaacctcta tataataagg caagggcact acaaatgcca agaaagtcac
    49021 aatcaaggcc gcaatgacgt ataagggcca tctaatcttt tttttcattt cttatttcct
    49081 ccaaaatact ctcgggaaca tagcaggcaa tatcctgacc aaacttcaaa agctctctaa
    49141 cgcctgatga actgatatag agatgttcag gtcgactatg taaataaata gtctctatat
    49201 cagaagacag ctgatgattg tagtaatcaa aactggcttc atattgcaaa tccgacgcat
    49261 tcctcaaacc acgcactaga caagtagcac ccaatctttt tgcaacatcg accaccaatt
    49321 catcatgaga agccacgact tcaacatttt ccaaatgtcc caaagccttt tctagccccc
    49381 gtttacgatt ttcaagaggg agaaatcctt gtttgtgggg attaaaaaaa atacccacac
    49441 aaagcttatc aaaaagtctg ctcgcccgtt caatgatatc cagatgccca tttgtcatcg
    49501 gatcaaatga gcctgtgaat aagccaatct tatctgacat agactgtcac cttactaatt
    49561 ccataaatct tttccttcca gatacccaga caggcaattt cttctggaag ttcaacgacc
    49621 ttatccgtct cgcacacaac cataacatct tcagaaaaaa gctctctctc agccattttt
    49681 tcaatatctg ctacgatttg ttccttggca tagggagggt ctaagaaaac gaggtcaaat
    49741 tccccagata cctgttccaa tgccctctct gcatccatct tgaggagttg aaattttcca
    49801 acttccttgg tcatctggat attttcagcc acgatggtct gagccttacg gtctcgctcc
    49861 accaaaacag cactggacat gccacgcgat actgcttcga tagataaacc accactacct
    49921 gcataaaggt ccaagactcg tcccccttca aagtagggac caatcatgtt aaaaatggct
    49981 cccctaacct tatccgaagt aggtcttgtt gtcttgcctt ctagtgtctt gaggggacgt
    50041 cccccataga ttcctgatac gattttcata ctgtttatta taccaaatta tagacaaaaa
    50101 gagaaagaaa accgaacctt gcggttcgat tctctacaaa atattttcgt aagtatcgcg
    50161 gacttcttga ggccaaacac ttgtttgcac ttctccaatg tgtctcttgc gaagtaggaa
    50221 catggccata cgagattgtc caattcctcc accgattgtc aatgggaata ggccattcaa
    50281 caaagacttg tgccattcca attccaagcg gtcttcatca cctgtaattt ccacctgacg
    50341 tctaagagtt tcttcatcta cacgaattcc catagaagac aactcaaagg ctccacctaa
    50401 agactcattc cagacaagaa tatcaccatt tagacccttg tagccattct cagactcgct
    50461 tgtccagtca tcatagtctg gtgcacgtcc atcgtgcggt ttaccatctg gcaactcgcc
    50521 accgatacca atcaaaaaga cggctccaaa ttctttacaa atcgcatttt cacgttcttt
    50581 cggtgtcaag tctgggtagc gttctaccaa ttcttctgta tggataaagg tgatttgttt
    50641 tggcaagata gactcgatgt catagcgggc ttcaacagct agctcagtca ggcgaatagc
    50701 cttataaatt ttctcaactg tttcttttag ataaacgatg ttacgcttac catttgggat
    50761 aaccttctcc cagtcccact ggtcaacata aacagagtgg gttgcatcca aggaatcctc
    50821 atctggacga agggctttca tgtggacaaa gagaccctct ccttcaccaa agccaaaacg
    50881 agccaaggtg tggcgtttcc atttagcaag tgagtgcacc acttcataag tagcatcagg
    50941 gatttggaga accttgaccg atactggatt ttccacacca gacaggttgt cctgcattcc
    51001 gtcaccgacc ttactcaaga taggaccttg aacttcgaca acttctagct tatctttcaa
    51061 atactgggta aaagtgtttt tgacaaagga aatttcttct tgttgatgga taaaactttt
    51121 cttcatagac aactcctcaa aaatttaata aacgtattat acacctattt ccaagaaaag
    51181 aaaagagaaa atttaaaaaa aaatcagtgt cactcaaaac actgatttca tagacctttt
    51241 agtcattgcg accaaagata cgtagaatac ttaggaaaag attgataaaa tcaagataga
    51301 tgctgagagc cattgacacc acccagcctg tcgctacacg accttgtgat tgttcatagg
    51361 cgaggcgaat cttttggtta tcccaagcaa tcaaccctga aaaaaccaaa accatggcta
    51421 cgctaatcat ataatcaaag aagccactag ccaagaaaat attgactacc atagcaatca
    51481 gtaaaccaat gagagctgcc atcattgctc gaccaatccc actcaagtct ttcttggtaa
    51541 aaataccaac tgccgccatg acaaagaaga gaagggcgct cgatacaaag gcagataaaa
    51601 ctgtacccgg agtatagaaa gccaccacaa aactaagggt aaagccgttt aaaacggagt
    51661 aaagtaaaaa tactggaaga gcagctggac tatttcttga agccatgcta ctggcaacga
    51721 aaaccaaagc caactccgca aaagtagcaa tggtcaacca gagacgcccc tgcatcaaaa
    51781 agtaaaccaa ctgagactga aagaccgtca acataaggcc tgataccaaa gcagatagtc
    51841 cgattcccag accaacaaag gcataaacct tagcgtaaaa ttgattgaga cctgcacggt
    51901 catgtataat agtgtgattc atccatttct ccttttctgt gaacatcttt ccttgattat
    51961 aacaaaaaaa gttaaaatta gcttaaatgg aagattaaaa taccggctgc aaccgcaaca
    52021 ttcaaactct cggcctgccc cttcatgcta atatggacca actggtctgc actttcagcc
    52081 ataaggggac taattccttg accctcattt cccataacta gtacaaaatt ttctatagaa
    52141 ggcagttctc tgtaatcaac agaatcttta gatagggttg ttgctagcac tgggatagct
    52201 acctttttag tttcgtcaag aagcgcttga ctagtcatcc ggtaaatggg cagatggaaa
    52261 tgactacctt gcatggaacg tagggttttg agactgtaga tgtctgccga cttatctgaa
    52321 acaatcactc ctgtaaaacc tgctgcatcc gcagttcgaa tgatagttcc tacattacca
    52381 ggatcttgca catcttccaa aaacaagaac ttgccctgac tcaaatcagc ttgtcctact
    52441 tcttcttttt gaaccacggc cacaattccc tgtggagtct gagaatccgc caaatctagc
    52501 aaaatatcct ctgacaccca gacagtttgc gaaaaagttg ctaactgatc tcgataattt
    52561 tctagggtaa agattttctc aatcgtcact ccagcttgaa cagcttcttc aaacaagtgc
    52621 cagccttcaa tcaaataggc tgacttgcgg tatttttttt ggtgtaattt cttggtattt
    52681 tttaccacag aattggcttt tgaggttata atagtcatag aaatattata acacaatcaa
    52741 aggggtttgg tatgcaaaag gttagaatga ttgcccaagg tagggtgcag ggagtcggct
    52801 ttcgttgggg tgtttatagc ctggcccttg aaatcggtgg catcacaggt cgggtatgga
    52861 ataacgacga tggtacagtg gagatcttag cccaagcaga ctcatcagct attatggcaa
    52921 aatttatcca agaaatccga aaaggaccga cacctttttc aaaagtcagt tacttagatg
    52981 tcaaactgag caactttcct ccctaccctg actttaaaat cgcaaattag gtctccagaa
    53041 ctattgtata ttttgtaaaa aaacagtaga atagaaaggt ataattttta aagaaggaat
    53101 aaaaacagtg aaatctatta aacgttttgc actctcggct atgggagtgg ctatgttgct
    53161 tgtcttgact ggctgtgtca atgtcgataa aaccacaggt cagccaacag gatttatttg
    53221 gaatacgatc ggagcgccta tggctgaagc catcaagtac ttcgctactg ataaaggtct
    53281 aggctttggt gtcgctatca ttatcgtaac cattatcgta cgcttgatta tcttaccact
    53341 tggtatctac caatcatgga aggcaacgct tcactctgaa aagatgaacg ccctcaagca
    53401 cgtccttgag ccacaccaaa cgcgtctcaa agaagcgact actcaagaag aaaaactcga
    53461 agcccaacaa gccctctttg ccgctcaaaa agagcacggt atcagcatgt ttggcggtgt
    53521 aggatgtttc cctatcctcc ttcaaatgcc tttcttctct gctatctact ttgctgccca
    53581 acatactgaa ggggttgctc aagcaagcta cctaggcatt cctctaggtt ctccaagtat
    53641 gattttggtt gcctgtgctg gtgtccttta ctatcttcaa tcgctccttt cacttcacgg
    53701 agtagaagat gaaatgcaaa gagaacaaat caagaaaatg atttacatga gcccactcat
    53761 gatcgtcgtc ttctccctct tctcaccagc tagtgtcaca ctttactggg ttgtcggtgg
    53821 tttcatgatg attctccagc aatttatcgt caactatatc gttcgtccaa aacttcgcaa
    53881 aaaagtccgt gaagaactgg caaagaaccc atcaaaagca agtgctttct caacaccaag
    53941 tggacgaaaa gacgttaccc ctgaacaacc aactgctatc acaagcaaga aaaaacacaa
    54001 aaatcgcaac gctggaaaac aacgttcgag ataagaagaa aaaggcttag ctgatttgct
    54061 aagtcttttt gcaagtcaaa agcccgatgt ttccatcagg cttcttttct atccatgtac
    54121 acgtttcata taatcttgat aactttcggt atccatgagt tgtttagcgt tcttgacgcg
    54181 atctgctgtt ggtggtttga ctccttcgag ggaatatgga attccaagtt cacgccactt
    54241 gaactcaccc atggtgtgat aaggtagaat ttcaaactta tcaacatttt tgagggtctt
    54301 gacgaactta ccaagttcaa tcaagtcatc atctctgtct gtcaatcctg gaactagcac
    54361 gtggcgaatc cagacaggtt ttccaatatc tgatagatac tgggcacaag ccaagatatt
    54421 tttattggtt tggctagtga caatcttgtg ctgttcttcg ttgatttcct tgatatccaa
    54481 aagaaccaag tcagtgacag ccatgagttt gtcaaacttc tcaaggtaac gcggtttatt
    54541 acggaaagga agagcacagg tgtccaaggt acagtggatt ccttgttcct tagccttggt
    54601 gaagagagca atcaggaaat caatctgcaa gagagcttct cctccactga ctgtaatccc
    54661 acccttattt ccccagaaac cacggtagcg caaggcctct gtcaagatat catctaccgt
    54721 ccgttcacgt gacttattgg actccatagc ccaagtgtct gggttgtggc aatactggca
    54781 acgcatgtga cagccctgca aaaagacaat aaagcgaata ccaggcccat ctactgaccc
    54841 aaagctttct gtcgaatgca ccattcctgt cacttgtcca taatcaattg tttcttcaga
    54901 catatcgtta ccttccttga aaacgtttta tagttttatt atatcacgac ttgaaggaaa
    54961 aacaagattt ttgcctattt tttagaaagc aatctgtttt tcaatttcat tttcaatcta
    55021 ttatcagatt attcttcaaa atcaaagcca tataaggttg caaaatagtc ctcagggcgc
    55081 tctgcacggc ggatttgacg ggctttacct tcttcggtat agaggatttc cgcagaacgt
    55141 aatttggcat tatactggta gcccattgaa aatccgtggg cacctgtatc atgaatgacc
    55201 agcaaatcac cgatttctgt atgaggcagt tcgcgattca ctgcaaattt atcattgttt
    55261 tcacagagtg aaccgaccac atctaccact tcagctggtc catctggatg ggtcacgttg
    55321 ctaatatgat ggtaagctcc gtacatagct ggacgcatga ggttgactgc tgaggcatcc
    55381 acacctagat aggtacggta ggttttcttc ttatgagtga ctcttgtgag caaagctccg
    55441 tgaggtgcca gcataaaacg acccaactca gtaaaaatct taacctgacc aagacctgct
    55501 ggcgtaagga cctcttcata caccttacga actccctcac caatcaaggc aatatcgttc
    55561 ggctcctggt ctggacgata attaacacca ataccgccag aaagattgat aaagtctagc
    55621 caaaggccca acttttcctt gatttcaaca gccagttcaa agagctgacg agccaactct
    55681 ggataataga gatgggtcac ggtattggac gctaggaagg agtgaagccc aaaagtcttg
    55741 gctccttttt ccttcaagat agcaaaggct tcaaagagct ggtccttggt catgccaaac
    55801 ttagcctccc caggattgtc cataatgtct gtccccagtt caaaaacgcc tccaggatta
    55861 taacgacaag agatgatttc tggaatacct gctgctctct ccagatgttc aatatcttca
    55921 aaggcatcca agttaatggt cgcacccaat tcacgtgcat aggcgtattc cttgtctggc
    55981 gtgttgttgg aagagaacat aatctcagaa cccagaaagt ccagtttatg gctcatcaaa
    56041 agctctacat aactagagca gtccacacca caaccttctt cttggagaat tttcaaaata
    56101 gctggagttg gagtagcctt aactgcaaaa tattccttaa agcccttgtt ccacgaaaaa
    56161 gcttggttga cggctcttgc cttctcacga atccccttct catcatacaa gtgaaaggga
    56221 gtcgggaact cggcaacaat cgcttctaac tcttctctgt tgataaatgg tgttttcata
    56281 agcttccttc tattctgttt gcaaagaaag gctgggacaa tcgttccaac ctttagttct
    56341 atctcttatt tatcttcgtc aaagatattg ccaacctcaa catcgatagc ttggttcttg
    56401 acatcaatat tggttacctt caagagtgac ttgtagtcaa actgcttttc acgttcttct
    56461 tgggcattgt ccgcaaagac cgctacacct gccagttctg agtcgaactc gcgcaagaga
    56521 ctaatcatac cgttgaccgt tccgccacct ttcaagaagt catccacaat caagacacgg
    56581 ctgcctgcct taagactacg ttttgaaagg aacattttct cgatacggtc accacttgaa
    56641 cctgaaacat agttgacgct aacagttgaa ccttcggtaa ttttcaggtc acggcgcaca
    56701 atgacaaaag agacattgag gacattggca actgcatttg caagtggcac acccttagtt
    56761 gctacggtca taaccgcgtc aattttttgg tccataaagc ttttggcaat aatacgacca
    56821 atatttttca agatggctgg tgtgctaagc aaatcagaca gatagatata accacctggc
    56881 aagatacgat cactttctga taacttggta cgcaagtctt caaccatttc cttagcatcc
    56941 tgactcgaaa tagacggtgt gaagatgaca cctccgccag ccccagtcac tgtctggata
    57001 tgaccgattt caatttcctc aaaggcgcgt ttgataatga cgatatcttc tgagatggat
    57061 gatttagcag actcatactt ttcagcaaaa gtattgagac tagttagttt ataaggatta
    57121 ttaatcaaat agttggaaat gacaaccatc cgatcacttc ttcttaattt catttctatt
    57181 tcctattcat ttttattcaa aaaatcaaaa agcaaactag aaagctggtc gctggtggtt
    57241 caaaacactg ttttgagatt gtcaatagaa ctgacaaacc ctgtaatata cctgcatata
    57301 tacatacgac aaggcgatac taccctagtt tgaagagatt ttcgaagagt attcattttt
    57361 gtcttttact tattatacca tattcacata aaaaaacgaa cattcttatc ctaaaaaatg
    57421 ctcatttttc ttaaattatc aatctaaatc tggtttatag aaggaacgat tatccatagc
    57481 gaagatttta ttggacatct ctcctttatc caccaaagcc agagctgttg acatcatcat
    57541 catgcttgca tccagattgt caatcatatg gataatctct gcctccataa tacgtggacg
    57601 gactggactt ccatattcaa gcaagccgtg gtgactgagg atgacatgac gaagcaaaac
    57661 gacttcttcc ttggtatcat cgatgccgag ttccataact gtcttggtaa tttcgctatc
    57721 aatgagagcg atatgtccaa gaagattacc tcgcactgtg tactctgtct ggtctggccc
    57781 cgtcaactcg atgaccttag ccaagtcatg cagcataatc cccgcataga gcaggctctt
    57841 attgagctga ggataaactt cgctaatagc gtctgccaaa cgcaccatgg tcgccgtatg
    57901 ataggccaag cccgtttcaa aggcatggtg gttggtcttg gcagctggat aggagtagaa
    57961 ttccttatca tacttggtgt agagatttcg gacaatccgt tgccagacag gattttcaat
    58021 tttgaaaatc atttgcgaca tgtagtcacg aatttccttg acatcaactg gtgacttgac
    58081 cttgaaatca gctgggtcat tgggttcacc agcttgaggc aggcggagag taatttgatt
    58141 gacttgaggg gtattgttat aaacttctcg gcgtcctttc atgtggacaa ccttacctgc
    58201 ggtaaaggcc tcaatgttat gaggttgggc atcccagagc ttcccatcaa tctcgccact
    58261 atcatcttgg aaggtaaagg ctaggtagtt tttcccagct cgagtttgcc tcaggtcagc
    58321 tgatttgatt aggtaaaagc cttcaaataa ctcatctttt ttcatgtgac taatcttcat
    58381 attcttcctc attttcttga aaatggagta gatcaagcgc aggctcacct tctgacaact
    58441 caatgtgacg gagcgtccgc tcgatagcta tggtacgacg gtttaataat tcatcaatat
    58501 tgccagaggc atgttggaga tgtttttgtg ccttgaccag aataccacca aacttgccaa
    58561 actcggtctt gacactggca agagtcttgc tgatatggtc ggcactcttt tggatattaa
    58621 gggtcttgaa accaactgat agggagttaa gaagggctga tagggtactt ggtcctgcaa
    58681 caataatctg ttcttcccgt ctcaaatcat caaagaagac cggattgcgg acgatttctg
    58741 agtagagacc ttctgtcgga acaaacaaaa ctccaaaatt ggtcgtccga ggtggtgcta
    58801 tgtacttgtt cctaatatcc ctagcaaagc gcttgacgct tgctaggagt gacttacgac
    58861 agcgttcaat ctcatccttg tcacctgtct cataggcttc ttccaagcgg taataatctg
    58921 ccagtggaaa cttagagtca attggcagat agacgtattc ttggtcgcct tgtccgggta
    58981 acttgatggc atactccact cgttcactag agttttcaac cgttgcgtat tctcgttcgt
    59041 actgggcagg tgtcatgatg tcttcaataa tttgccccag ttgcaattct cccagaatcc
    59101 ctcgcgtctt ggttccagag agaaccttgt taagagctcc gacatcacgg gcaactgtct
    59161 gcatttctcc aaggccacga ttgacagact ccagttgttt agaaactgtc tcaaaggaag
    59221 cctgtaagcg tgtctgcaag gtcttttcta gtttttcctc gaccgtctgg cgcatttgtt
    59281 ccaaacgttg ctcatttgat tcctgcaagg cttggagacg ttggtctgtc ttgtctctag
    59341 tttggaggag attatctgtc atttcttgac ggacttgggt cagaccttgg tgcaattcaa
    59401 tccgcacttc ttgcaaacgg tcgctgacaa ccacttccaa atctttttgg tctaactggc
    59461 tggcttgtct ggcttggtca aagcggtaat ccaactggtc tgacaaatga tctgcctgat
    59521 cctccaagct cttacttaag tgtttctcct gcctatcctg cctttgccaa atcagaaaga
    59581 gaccagctag attggcaatt aataatagaa taagtaaact ttccatccta cctcctgtcc
    59641 ttgctatgca gtacgaccac ataaccatct gggcaagtta ccgacacttc cctatctata
    59701 tattcgttag aagcgtacac ttttttaaag aaaaaatttt cctctgtcaa ctcatacttg
    59761 gctccaagaa tagtcagctg gctatcccga actggcataa aggctagata gtcgtagtct
    59821 gaacgaggtt ctagctgact gattccttct ggacaataag taatcaagtt ttgcccatcc
    59881 tcaatttcta tttgatgcat atagggtgcc aacttaggat tgctaggcag aaagacattg
    59941 gccaacatat ggtcaatacg gccacccaag gcaccgaaaa tagtgacctg agcctgagga
    60001 ttttgttcaa agatggttaa gagagccaat tccagatctg tatcatcctt ttctggtcgt
    60061 gcttggacaa aatactgggc acctttttga atcacctgtc gctcttcttc cgtcacagaa
    60121 tcaaaatctc cgactgctag agcaagaggt aagtcttctt ccaagaccca gagcgagcct
    60181 cgatccaccc caacaaaagc atcaaaatct gtccgataat gaccgcggtt tccgcctgca
    60241 aaaactgcaa ccctagtcca gttgttttct gagagtttgt actcgctcat tgacttctcc
    60301 cttaaagaca taggaacctg ctacaaaaac agtcgcaccg gcttctttgg cttgagcaat
    60361 agtttggtca tcaatcccac catccacttc gatttcaaag ttcaaacctt tttcctcacg
    60421 aagagcaacc aactcacgaa ccttatccat ggtttctggc agaaaggctt gcccaccaaa
    60481 acctggatta accgtcatga ctaaaacttg gtcaactaga tgaaggacgt gcttgatggc
    60541 ttcaactggt gtgccaggat tgataacgac tgaaggctta actccgagtg aacgaatttt
    60601 ttggagggcg ccatgaatat gaggtgttgc ttctacatgg atactgatga tgtctgcacc
    60661 tgcacgcgca aaatcttcca gatgatgctc agggtttgac accatcaagt ggcaatcgaa
    60721 aaccatctta ctatgaggac gaaggctctc gaccacacct gcaccaaaac tgatttgcgg
    60781 tacaaaatga ctgtccatga tatcgatatg ggcatattct gccccagttg cttctagacg
    60841 tttgatttca cgttcaaagt tggcataatc tgctgccaga attgacggag caatcttgta
    60901 ttgagacata ggtttctcct tattttggaa tttttttgct gactttttta taggtttctc
    60961 tacgattttc aatttcgctg aggaattgca ggtagttgtc aaaacggaag gtggcaatgg
    61021 tcccctcttc tacagctggc ttgacggcac aagacggctc atgggtatgg gtacaagtac
    61081 gaaacttaca atctcggctg acagtagcaa tctctgggaa agcctgattg aggtcttcag
    61141 cccttgatac ttcatagtcc agagatgaaa agcctggtgt gtctgcgatt ttacccccgt
    61201 tgagattgta aaaactaaca gctcgagtgg tatggcgacc gcgacctaga ctgtctgaaa
    61261 tttctcccgt ttcaagattg aggtctggta cgagtttatt gagaagagtt gacttcccaa
    61321 cacctgtctg ccccataaag accgtaacct tgcctgttaa caaagacagg agttcctctt
    61381 tactggtcac aaagtcatag ccgatgtcac cataggtctg ccggtaaaaa tccagttctc
    61441 ccctatcttc caacaaatcc attttggaaa tatagacaat gggatggatg cccttgtgct
    61501 ccaaaagaac caagaaacga tccagcaaat tgctgttaaa atcaggttcc ttgacggaca
    61561 tgattactac agcttgatcg atattgacaa taggcggacg aaccagactg tttttccgtt
    61621 cgtgaatttt taggatatag ccttctgaat tttcctcggc agagaaatcc acccagtccc
    61681 caacataagg ggtatggcct tttttacgga aattcccacg cgcgcgtgtt tgataaacct
    61741 ggccatcact ctccacatag tagaaacctg ccaaggcttt aatgatttgt ccctgcatct
    61801 tagagtcctt gccctttaag tgcgtctgct agaccggcaa attctgccaa gctgagagct
    61861 tccccacgca cacttggtga caagcctgcc tggtccaaag ccttggtcag cttgtccttg
    61921 acctcttcag tcttaccaaa gtaacctgtc aagttattcc acaaggtctt acggcgatgg
    61981 gtaaaactag ccttggaaac cttaaagaag aagttctcat cttccactgc tacagctggc
    62041 tctggacggc gcaccatttt caagatggct gaatccacat ttggcgctgg cacaaagacc
    62101 gtacgaggca cgataaaggc aaccttggct gtcatgtaat actgcacggc gatagacaag
    62161 ctaccgtaag ccttggtgtt aggctgggct gaaatgcggt ccgctacttc tttctgcatc
    62221 atgaccacaa actcactaaa aggaatccca ctctcaatca agtgcatgag aataggcgtc
    62281 gtgatgtagt aaggcaaatt agccactacc ttgattgaca ggttaggatt tttaaaattt
    62341 tggatatgtt gcgccaaatc aaccttgaga atatcttcgt taactacagt cacattatca
    62401 aaatcacgca gggtatctgc caaaattggc accaaacggt ggtcaatctc aaaagccatg
    62461 acttgggctg cacgctcagc caaaaattct gtcaaggcac caatacctgg cccgatttcg
    62521 atgacattga cctgatcatc aatttcagcc gtatccacaa ttttttgaag gatattggta
    62581 tccgtcaaaa aattttgccc aaaggacttt ttaaaggtaa aaccgtgacg ctccagcact
    62641 gccttggtca cgctataatc tgcaattctc atctattctc ttttctatta tctgttacta
    62701 ctattgtaac acattcccct tgtattttgg gaatgaaaat cataccaaaa aactatcttt
    62761 cctcatgaag aaagatagtc ttggaaatct ttaaaagtgg ccttagcagt tctctcgaaa
    62821 catgcgttca aaaaaatcag cttcttgata acttcgattt tcgggtaggg ttaaatccac
    62881 atcctcttcc acatcatcca ctgtcagttc aaccgtttga ggtaaatttt tcaaacgata
    62941 atgcttttgc ctttaccctt caatactagc aaaatcaagc aaatagccat gcactcggat
    63001 ttgaaccaaa aggagatgat tggtcatatt ttccatgatg aggatatctt ctaaaccacc
    63061 tctggcacta ggataatcag ataccctgcg aatacggatt ttttcacaca tgagcaagtt
    63121 tcctcatatc aatgatttca tcagccttat tccagactag gggattatgg gtcgcaatga
    63181 tgataattcg attttcatct ttcaaatcca ccaagagatt cataacctcc tctgaatttt
    63241 caggatcaag agctgctgtt ggttcatctg ccaaaatcaa gggtggattt ttcaaaatag
    63301 tcttagcaag ggcaactcgt tgggcctctc ccccagataa agtatagatt ttttgttcta
    63361 aatccaaata ccctagatta actttttcta aagcccccac ttgcctttcc aaacgttcta
    63421 cttttgagat tttctgacca acaaaaccca aatccaaatt ttctttgatt gattggtttt
    63481 ctaagaggcc aaaattttga aagagatagc ccatctgatc tcgaaaatac tcacgagtgg
    63541 gaatggtttt taaatctttc ccctgataga gaacccttcc tccatctatc ttttctagct
    63601 ttcccaagat attcagcagc gtcgtctttc cgcttccact ctttccgatt aaggcataaa
    63661 ccttgccctt ctccagcttg agattcaaac cagagaaaat cgcgcggtca ttaaatttct
    63721 tttccaatcc ttgaatatca atcatcttat tttcctttca atactgccat gctaccagct
    63781 tcttcttttt tgtcctgcct tactaaaatc aagagggcgt taagcgtaaa caaagctaca
    63841 actagagcac taatcaaacc atctcttgtc aaaatactag ataggactag gccaagcaag
    63901 agaactcctc cttgcgccag taaatacttg ccatgaagct catagattgt cataccagca
    63961 agacgtttaa tcataagctc ccgtctgaac tgctcaaaat agagaagatt catggaatca
    64021 aataacaaga tagccgtaga cagggtcaaa atcgtcccaa taaggagaga gtaaaactcc
    64081 acccgtttgt catttagtac cttggcaaaa aatagctggc tttttaccaa gtaagaaacc
    64141 ttgtgataca gaccttgctc ttttagagct gtgatgctgt ctccatatcg atctagtttc
    64201 aaggcactat tagccgtagt tccccacaac atccctgcaa caggtcttgt tccagtcgct
    64261 tgcggcgtta gaactacaat aatcggatct tttaggtact ggcgtgttgt cttgtaccca
    64321 tcattataga ggaaacgttc ctgtcctgtt tctgtaaaag ctagccttac ctgtgggagg
    64381 tagtgtttct gactcgtcac ttctacactt tcagatgaaa agttttgcag gtaatctgta
    64441 aacaatcctt ggtagtagac agactgctct cgcaagctct caggcaagat cagcccaaac
    64501 tctccctcag acaagttttg catcttgtcc ataaactctg aagaaacggt aatcttttct
    64561 tctatcagat agcgtggtga gacatagata acattccctg acggtgtgta gtcactgaga
    64621 cgattgccat ctaggtccac ttctgctcca tctgagaaat tgtcaacatt gctcataata
    64681 taaaaagagt ctgtattggc taaccgttct tcagtaaatg tctgccactc acgattatcc
    64741 ttacgcgttc cttcttcatc ggcaaatgca ctagaccaac caaaggatag acggtaacgg
    64801 tctgaggact ggctccattt attgctagct ctctccattt cctgcatttc acggtagtgg
    64861 ggtaggagag ctgtcgcact cgatccgacc accaatacag ctaagagttg ccccaccatc
    64921 atcaatgtca ttatacgttt gagagggagt ttccctttca atagatccac cagactattt
    64981 tcctgtaaac caagtagata gacgacactt agtaaggtag aaatccctgc cagggtcaat
    65041 ccataaagta gaagagcaat gatgaccagt tgcaccgttg ccataaacaa ggcaccttga
    65101 taccagagaa tccccaatcc caaaagactg gataccagca ctgagcagat aagctgtctc
    65161 acatcttcta acactggtct gagagcaact ccaaacaagc tctcaccagc tattaagcga
    65221 atccctgcct gacgaaggga tttgatccga taaatcaggg tcagactcat aaaggtcagc
    65281 agaaaaatag ctaaactcag tagcaccata ggggtggccg tcaatagtaa gactatcgaa
    65341 aatggatctt ctccattcga aacaaagcct tgataaccaa gctctttcaa ggtggtctgt
    65401 aagctcactc catccaaact tcctgatgca atcaagtaag accctaataa atcactcgtt
    65461 tctgcactct ccttggagga aatggtcaga ccttctggaa gctttccctc accataagtg
    65521 gcataggtaa agcgtgtttc tccagcttca tttggctcaa cgattcgacg agcaatgaga
    65581 ctattgtgct ctaccgccaa gtgactcaaa gcctctgtca cctcttcgcg actagctact
    65641 ggttgattta tcatcattcc tgtcacatca acagaaggat agttaccaaa taaaatctct
    65701 tctcgatggt caacggaagt tatcaccata taaagcgata ctaataccat tgaaatcaaa
    65761 ataaataaac gtttcatcat ttcctccaaa aagttacttg gtcacttagt gagaaggtga
    65821 ccaagtaaag ctaaacaata gggctatacc attctaaaca ttatagtaga atgcaacttt
    65881 ctctccccaa gaagtacgaa tccatgcacg agaagtccct ccagcaccag catatccctt
    65941 gtcagatgaa ccagtttttc tgctaacaac tgttgaacta tggtattttg aagggtgata
    66001 gtagtttgag taagcaccac cgttacctga accataagtc caaacaccac cttctgggta
    66061 ttgaacggct gcagaggcaa ctgatacacc tccacctaat gttgctgcaa tgctcgctac
    66121 aagagctaac tttttaactg tttgtttcat attgatactc ctctattttt gattacaaga
    66181 ttgttgagtt acttgctcct ctttccatta tcaacgttga tactattata ttaccaaatg
    66241 atattctaaa attatttgtt tttctctaaa ttgtcaaaat agcaccctga aatgaacttt
    66301 tatagtcatt atactccatc tttatcacac tatcaaggac atcaatgtcc ttaaaatcta
    66361 actatttcat attattttta gcttatatct aaaaaaacag ttctaaagac gaactttaga
    66421 actgttttga tacgaggaca aggacatttt tgtcactgat tcactatgtt tataaatatt
    66481 ttttgacatc ctcttgccat tcctctgtca atttctttac tagaaattca tctccaatta
    66541 gctgcgcaaa tgttttagaa gactgataaa atgattcagc taaactaaaa tctctttcta
    66601 ctcttaatgc ttgcttccac aaaaacataa atacaagagg tttcttttga taatcttgag
    66661 ttttatccat aatttcttgt aaacacgata gataatcatt aaaacaatca gttactccta
    66721 ccttttcaag acaacacatt cctgaaataa gagtatctct aattataaag taattctcta
    66781 tttgagttac cttcttctgt tccaaaagaa agagcattag cttttcgatt tgatttataa
    66841 atttggcaag atcttttcta atgagcattt gataaaaaaa caaacgaatc aacaacatat
    66901 catttattga ataagcttct ttttctataa tctgaggcat atgttcctca agtattaact
    66961 ctgcatattc aggccttcta gttctagaag tatccaaaca cgcctgcaat acttcacatg
    67021 ctaattgttc ttctttagga agattatcaa agtatgtttt ataaatgttt tataaatctc
    67081 ttccaaacac gcttccttct tatcgtactc ctcttcttta ccatagattg gttcacgtaa
    67141 aatctggtat ttcaattcta aataagcagg aggaagagct gaaaaatccg gcataaggct
    67201 ataaactgga actcctagcc ggcgagcaat ataggctaac ttgggcaaac tcggttgcga
    67261 agctccactt tcaattcgcg acagttgacg aactgtcagt tcttgctcat ctccacaaaa
    67321 atctggacga ctaattcctt tttctatccg aatctcttta attttttgac caattaacat
    67381 cagacgcctc ctcttctacc tgcttcgaaa aatactgtga aacttaaaaa attgtaacgg
    67441 ctacatcttt cctactcata agatttcata gcttcttcca cttctgccaa agtaacccca
    67501 aacaactcta ggcgtttgag gagttgcttg ccgttggaat agccgattcg gagagtctct
    67561 ccgagatatt ctctacgctt acggctgtct gcccctgcta gaaaaccaag gcgaatcaaa
    67621 tcgctacgac taatgtcaaa ctgactctca tgttcaaatt gttctgtcac ctgagctaga
    67681 gccgttttca ggtcttcata gctggcatgc tcaattccca gagaacgccc cttggtcttg
    67741 gacttgggaa cagcttcatc tcgcttgaga aatgcatgct gaactgttgg aatgaccatc
    67801 atgatcatgc gccgaatccg ttccccatta aaatctgggt ctgtaaagac aatgactcca
    67861 tgacgttggt gcaggcgctg aatccgctct atatcctgag cattgatggc agaacctcga
    67921 gtctcatagg tctccacatc gaaataacgt ttgagattga ccgtatcatc acgcccttca
    67981 accacgataa cttgagaaat tttctctttc attacttgct gtccagtcca aaaattcgtt
    68041 ctgcatttgc agtcgttgct accgccagct cttctgtcgt cataccacgc aagtcagcga
    68101 taaagtcgac cacatagcga gtataggctg ttttattttc acgaccacgc ttgggtacag
    68161 gtgctaagta aggcgcatct gtttccacca acatcttgtc caaaggtaac tctttagctg
    68221 cttcttggag gtcagttgcc ttcttaaaag tcaccactcc tgagaaggaa atggtcatac
    68281 caagatccac aaacttctct gcccactcaa gcgtccctga aaatgaatgc atgataccac
    68341 cacgaggacc aacgccctca ctcttgataa tctcataggt atcttccagc gcatcacggg
    68401 tatggacaac aaaaggcaaa tccaagtcct tagatagctg aatctgacgg cgaaaaacct
    68461 gctcctgcac ctctttgggc gctgtcatcc aatggtaatc taagccaatt tcacctaaag
    68521 ccacaacctt ggaatgtttt aacttatcca acaagtaagc ctcaacttcc tctgtataag
    68581 taccagcttc tgtaggatgc caaccaatag tcgcatagag ctgctcatac tcatctacca
    68641 actccaaggc atgctcaatc gtcggtttat caaaaccaac aatattcatc tgtgtcacac
    68701 ccatctcagc agccaaggca atttcttctg cctcacgacc tgcaaattct tctacattca
    68761 agtgtgtatg tgtatcaaaa atcatctctt ctaacctcgt tttctatctt ctattatacc
    68821 aaaaaagagg aggggcacct aatttttcgg tttcccctcc tctcttcaat agagagctat
    68881 tctgctatct tttctatccg atattgccca tctcctattc cacagttaga gacagaagag
    68941 attggctaca ttgatagaat attcctattc agctaaagta tgtgattatc ttgggttctc
    69001 acttttctca cccatcacta ggattgatga cttctcaaaa tcccccttat aatctaactt
    69061 taagtagaga atagaatttt ctagctgttc tattttctac gtctagtctt tcttcctagc
    69121 aaagcaaaac cacttgttgc caccactaga ccaagactag caagtgctgc acttgatgct
    69181 gaacctgtgt taggtaattg tttgctagca ggtgactggt aggtaacatc ttgcattgtt
    69241 cctgcagttg cttgcggtgc acttgttgtc ttaggagcag cattaggagc cactggtctc
    69301 ttaggaactg taaccatggc aatggcttgc actccaatcg tttctgcttc cttcacatct
    69361 tccatagttt tcgcattttc aatctctttg agagctgctt gtttttctgc ttccactctt
    69421 gctaaaagtt ctgctttttc tttatcagaa agcggtgcgc ctttgatttc atcctgcttg
    69481 tccttggctg ctttttcaat ggcattttta gctgattctt tttcagtagc taattgctta
    69541 gaagcttgtg attgagctga gttttgtgaa cctgtgtgag ctgatccacc cgcctggcta
    69601 ccaccgcctt cattcgcatt agcatctgag cttccagtat tgcctccctt atctccacct
    69661 ggtgtatttt ctagcttata ctctggtgta gcttcttgag ttacagattc acctttcgca
    69721 gattgttgaa ctgtatcttt tcctagaatc gtcactactg aaccatctgg gaatgtgatt
    69781 gttgctgtac catctccagc tacattgatt gtcgctccgt ctaatgctga accatttgct
    69841 tgtaaaatag caaccttaac tttttcttca tctgttaaat gagttatatc ttttacatct
    69901 actctttgag caggtgcttt aacagttgat ttttcagcag tcagtttagt gctatcttgt
    69961 gcttttggat cttgtgctac caattgattt cctggaattg taatagctga accatcttta
    70021 aagacgattg ttgctgtacc atctccacct acttcaactt tatagtaaaa taaaataata
    70081 acaggacaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag aaacagaggt
    70141 gtactattct agtttcaatc tactgtaaca tcgcttccga atccatttgc atctactgaa
    70201 cttttttaca aaaataaaaa tcagtagact cgagttccta ctgatttttg atagaattcg
    70261 tttggattat gcagccaaaa ctttgcgtcc tttacgacga cgagctgcca atacgcgacg
    70321 accattttta gttgacatac ggttacggaa tccgtgtttg cgcgcacgac gaagtttact
    70381 tggttgataa gtacgtttca cgatgaatac ctcctcatag attttgtatt cgtttagccg
    70441 gctataaagt gatcagttac taaacatact ttactattct atctgattct ttcacttttg
    70501 tcaatagctc taggcaaatg tttccagctt tttcggatgc aagccct
//
LOCUS       DAVLTT010000004        69084 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLTT010000004 DAVLTT010000000
VERSION     DAVLTT010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 69084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69084
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.004"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            84..491
                     /locus_tag="VYN15_000252"
     CDS             84..491
                     /locus_tag="VYN15_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1451639.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIKNLKRGSHKWAIESWKKQHKIG"
     gene            656..955
                     /locus_tag="VYN15_000253"
     CDS             656..955
                     /locus_tag="VYN15_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV1451640.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            1286..1609
                     /gene="tnpB"
                     /locus_tag="VYN15_000254"
                     /pseudo
     CDS             1286..1609
                     /gene="tnpB"
                     /locus_tag="VYN15_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(2338..4065)
                     /gene="ezrA"
                     /locus_tag="VYN15_000255"
     CDS             complement(2338..4065)
                     /gene="ezrA"
                     /locus_tag="VYN15_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV1451641.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(4147..6093)
                     /gene="gyrB"
                     /locus_tag="VYN15_000256"
     CDS             complement(4147..6093)
                     /gene="gyrB"
                     /locus_tag="VYN15_000256"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV1451642.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALACYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(6108..6671)
                     /locus_tag="VYN15_000257"
     CDS             complement(6108..6671)
                     /locus_tag="VYN15_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1451643.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(6756..7310)
                     /locus_tag="VYN15_000258"
     CDS             complement(6756..7310)
                     /locus_tag="VYN15_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV1451644.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(7321..8544)
                     /locus_tag="VYN15_000259"
     CDS             complement(7321..8544)
                     /locus_tag="VYN15_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1451645.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(8581..11031)
                     /locus_tag="VYN15_000260"
     CDS             complement(8581..11031)
                     /locus_tag="VYN15_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV1451646.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLTQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(11231..12160)
                     /locus_tag="VYN15_000261"
     CDS             complement(11231..12160)
                     /locus_tag="VYN15_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1451647.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMNRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            12300..12587
                     /locus_tag="VYN15_000262"
     CDS             12300..12587
                     /locus_tag="VYN15_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV1451648.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(12621..13955)
                     /gene="ciaH"
                     /locus_tag="VYN15_000263"
     CDS             complement(12621..13955)
                     /gene="ciaH"
                     /locus_tag="VYN15_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV1451649.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13945..14619)
                     /gene="ciaR"
                     /locus_tag="VYN15_000264"
     CDS             complement(13945..14619)
                     /gene="ciaR"
                     /locus_tag="VYN15_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV1451650.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(14728..17274)
                     /locus_tag="VYN15_000265"
     CDS             complement(14728..17274)
                     /locus_tag="VYN15_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV1451651.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMILSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(17397..17837)
                     /locus_tag="VYN15_000266"
     CDS             complement(17397..17837)
                     /locus_tag="VYN15_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV1451652.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTSESKVVLEEFRKVYPL"
     gene            complement(17812..18681)
                     /locus_tag="VYN15_000267"
     CDS             complement(17812..18681)
                     /locus_tag="VYN15_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV1451653.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(18723..19451)
                     /locus_tag="VYN15_000268"
     CDS             complement(18723..19451)
                     /locus_tag="VYN15_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1451654.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILDSLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(19459..19938)
                     /locus_tag="VYN15_000269"
     CDS             complement(19459..19938)
                     /locus_tag="VYN15_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1451655.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(19949..20647)
                     /locus_tag="VYN15_000270"
     CDS             complement(19949..20647)
                     /locus_tag="VYN15_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV1451656.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(20640..20906)
                     /locus_tag="VYN15_000271"
     CDS             complement(20640..20906)
                     /locus_tag="VYN15_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV1451657.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(20972..21898)
                     /locus_tag="VYN15_000272"
     CDS             complement(20972..21898)
                     /locus_tag="VYN15_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV1451658.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(21973..22788)
                     /locus_tag="VYN15_000273"
     CDS             complement(21973..22788)
                     /locus_tag="VYN15_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451659.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPDPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFLLFRGFKKIKWSEV"
     gene            complement(22792..23112)
                     /locus_tag="VYN15_000274"
     CDS             complement(22792..23112)
                     /locus_tag="VYN15_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1451660.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVKTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(23454..23534)
                     /locus_tag="VYN15_000275"
                     /pseudo
     CDS             complement(23454..23534)
                     /locus_tag="VYN15_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(23578..25575)
                     /gene="metG"
                     /locus_tag="VYN15_000276"
     CDS             complement(23578..25575)
                     /gene="metG"
                     /locus_tag="VYN15_000276"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV1451661.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYAIALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(25699..26958)
                     /locus_tag="VYN15_000277"
     CDS             complement(25699..26958)
                     /locus_tag="VYN15_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1451662.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESL
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(26960..27661)
                     /locus_tag="VYN15_000278"
     CDS             complement(26960..27661)
                     /locus_tag="VYN15_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451663.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(27645..28844)
                     /locus_tag="VYN15_000279"
     CDS             complement(27645..28844)
                     /locus_tag="VYN15_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV1451664.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KTDEATN"
     gene            29130..30476
                     /gene="gor"
                     /locus_tag="VYN15_000280"
     CDS             29130..30476
                     /gene="gor"
                     /locus_tag="VYN15_000280"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV1451665.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            30673..31209
                     /locus_tag="VYN15_000281"
     CDS             30673..31209
                     /locus_tag="VYN15_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV1451666.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            31260..31346
                     /locus_tag="VYN15_000282"
                     /pseudo
     CDS             31260..31346
                     /locus_tag="VYN15_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(31415..31630)
                     /locus_tag="VYN15_000283"
     CDS             complement(31415..31630)
                     /locus_tag="VYN15_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV1451667.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            31728..32048
                     /locus_tag="VYN15_000284"
     CDS             31728..32048
                     /locus_tag="VYN15_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451668.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(32078..32416)
                     /locus_tag="VYN15_000285"
     CDS             complement(32078..32416)
                     /locus_tag="VYN15_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451669.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(32428..33147)
                     /gene="trmD"
                     /locus_tag="VYN15_000286"
     CDS             complement(32428..33147)
                     /gene="trmD"
                     /locus_tag="VYN15_000286"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV1451670.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(33137..33655)
                     /gene="rimM"
                     /locus_tag="VYN15_000287"
     CDS             complement(33137..33655)
                     /gene="rimM"
                     /locus_tag="VYN15_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV1451671.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(33686..34474)
                     /locus_tag="VYN15_000288"
     CDS             complement(33686..34474)
                     /locus_tag="VYN15_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1451672.1"
                     /translation="MKRFEVSTEIGSLSVAYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEALEELGISEYILCVHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(35051..35290)
                     /locus_tag="VYN15_000289"
     CDS             complement(35051..35290)
                     /locus_tag="VYN15_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV1451673.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(35310..35582)
                     /gene="rpsP"
                     /locus_tag="VYN15_000290"
     CDS             complement(35310..35582)
                     /gene="rpsP"
                     /locus_tag="VYN15_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV1451674.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            35752..35961
                     /locus_tag="VYN15_000291"
     CDS             35752..35961
                     /locus_tag="VYN15_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451675.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            36440..36652
                     /locus_tag="VYN15_000292"
     CDS             36440..36652
                     /locus_tag="VYN15_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451676.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            36735..37538
                     /locus_tag="VYN15_000293"
     CDS             36735..37538
                     /locus_tag="VYN15_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV1451677.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(37594..39135)
                     /locus_tag="VYN15_000294"
     CDS             complement(37594..39135)
                     /locus_tag="VYN15_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1451678.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(39137..39619)
                     /locus_tag="VYN15_000295"
     CDS             complement(39137..39619)
                     /locus_tag="VYN15_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1451679.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(39619..40704)
                     /gene="rlmN"
                     /locus_tag="VYN15_000296"
                     /pseudo
     CDS             complement(39619..40704)
                     /gene="rlmN"
                     /locus_tag="VYN15_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
     gene            complement(40725..41255)
                     /locus_tag="VYN15_000297"
     CDS             complement(40725..41255)
                     /locus_tag="VYN15_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV1451680.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(41411..42016)
                     /locus_tag="VYN15_000298"
     CDS             complement(41411..42016)
                     /locus_tag="VYN15_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV1451681.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(42189..43226)
                     /locus_tag="VYN15_000299"
     CDS             complement(42189..43226)
                     /locus_tag="VYN15_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1451682.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(43260..44195)
                     /locus_tag="VYN15_000300"
     CDS             complement(43260..44195)
                     /locus_tag="VYN15_000300"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV1451683.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(44748..45938)
                     /locus_tag="VYN15_000301"
     CDS             complement(44748..45938)
                     /locus_tag="VYN15_000301"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV1451684.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(46153..47496)
                     /locus_tag="VYN15_000302"
     CDS             complement(46153..47496)
                     /locus_tag="VYN15_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1451685.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(47636..48451)
                     /locus_tag="VYN15_000303"
     CDS             complement(47636..48451)
                     /locus_tag="VYN15_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1451686.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSLQVSDHYGLNAILNWK"
     gene            complement(48503..50683)
                     /locus_tag="VYN15_000304"
     CDS             complement(48503..50683)
                     /locus_tag="VYN15_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1451687.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVTAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(50969..51895)
                     /locus_tag="VYN15_000305"
     CDS             complement(50969..51895)
                     /locus_tag="VYN15_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1451688.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(51888..52580)
                     /gene="ftsE"
                     /locus_tag="VYN15_000306"
     CDS             complement(51888..52580)
                     /gene="ftsE"
                     /locus_tag="VYN15_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV1451689.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(52598..53693)
                     /gene="prfB"
                     /locus_tag="VYN15_000307"
     CDS             complement(join(52598..53620,53622..53693))
                     /gene="prfB"
                     /locus_tag="VYN15_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV1451690.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSYEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(53801..54457)
                     /locus_tag="VYN15_000308"
     CDS             complement(53801..54457)
                     /locus_tag="VYN15_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1451691.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(54765..55475)
                     /locus_tag="VYN15_000309"
     CDS             complement(54765..55475)
                     /locus_tag="VYN15_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451692.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVASGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(55475..56239)
                     /locus_tag="VYN15_000310"
     CDS             complement(55475..56239)
                     /locus_tag="VYN15_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451693.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(56239..57195)
                     /locus_tag="VYN15_000311"
     CDS             complement(56239..57195)
                     /locus_tag="VYN15_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1451694.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGTLLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(57199..58068)
                     /locus_tag="VYN15_000312"
     CDS             complement(57199..58068)
                     /locus_tag="VYN15_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1451695.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(58336..59496)
                     /locus_tag="VYN15_000313"
     CDS             complement(58336..59496)
                     /locus_tag="VYN15_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1451696.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(59597..59845)
                     /locus_tag="VYN15_000314"
     CDS             complement(59597..59845)
                     /locus_tag="VYN15_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV1451697.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(59924..60514)
                     /gene="clpP"
                     /locus_tag="VYN15_000315"
     CDS             complement(59924..60514)
                     /gene="clpP"
                     /locus_tag="VYN15_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV1451698.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(60688..61317)
                     /gene="upp"
                     /locus_tag="VYN15_000316"
     CDS             complement(60688..61317)
                     /gene="upp"
                     /locus_tag="VYN15_000316"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV1451699.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(61406..61873)
                     /locus_tag="VYN15_000317"
     CDS             complement(61406..61873)
                     /locus_tag="VYN15_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV1451700.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(61892..62449)
                     /locus_tag="VYN15_000318"
     CDS             complement(61892..62449)
                     /locus_tag="VYN15_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1451701.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFRETRKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            62574..63419
                     /locus_tag="VYN15_000319"
     CDS             62574..63419
                     /locus_tag="VYN15_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1451702.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            63478..64653
                     /locus_tag="VYN15_000320"
     CDS             63478..64653
                     /locus_tag="VYN15_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1451703.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            64673..65128
                     /locus_tag="VYN15_000321"
     CDS             64673..65128
                     /locus_tag="VYN15_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1451704.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(65157..65897)
                     /locus_tag="VYN15_000322"
     CDS             complement(65157..65897)
                     /locus_tag="VYN15_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1451705.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAVYVQTNAE"
     gene            66125..67472
                     /locus_tag="VYN15_000323"
                     /pseudo
     CDS             66125..67472
                     /locus_tag="VYN15_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(67512..68456)
                     /gene="manA"
                     /locus_tag="VYN15_000324"
     CDS             complement(67512..68456)
                     /gene="manA"
                     /locus_tag="VYN15_000324"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV1451706.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(68577..68873)
                     /locus_tag="VYN15_000325"
     CDS             complement(68577..68873)
                     /locus_tag="VYN15_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV1451707.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIYSNGASIG"
BASE COUNT        20431 a        15028 c        12564 g        21061 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tcaaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaatcacg taagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgttataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 taacaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcagag
     1201 gaaaggtatt gtactatgat gattgtacta tgatgattgt actatgatga ttgtactatg
     1261 atgattgtac tatgatgatt gtactatgat gattctacta agtgatttag gtcaagttca
     1321 ccttgtttgt ggcaagacag atatgaggca gggaatagac tcattagcct atgtagttaa
     1381 aacccacttt gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa
     1441 agaccgcttt aaagcccttt actgggatgg tcaaggattt tggctactat ataaacgctt
     1501 tgagaacgga aaactgactt gaccaagtac agaaaaggat gtcaaagctc tcgcacctga
     1561 acaagtagac tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac
     1621 tagaatagta cacccctact tctaaaacat tgttagaaat cgatttgact gtcctgatca
     1681 atttgtcctg ttcttgtttc attttactat agaacgattt gaaggcgttt atgatattta
     1741 gctgtacgag agtcttttaa aagtgttttg atggtttgga tttcttcttt agttgatttt
     1801 atattactat tatataatgc ttttttattt tagtctagta taaatagcga gaaatatcta
     1861 tcctatcttc tagaatgtct tccaaacgag aaaactctcg taaacaaaga ggttttagag
     1921 gcctatttac cgtggactaa agttgtacaa gaaaagtgca aataagaaat ctccagatta
     1981 ggaactatcc gtgagttctc tagtctggag atttttcaat agacttcgtt attggacggt
     2041 taccaagtta ctcaaagtac agatttgaag ctgcagataa gactgacgaa atcactttaa
     2101 tactaaatga aaatcaaaaa gcaaactaag aagctagcct caggctgtac ttgagtacgg
     2161 taaggcgacg ctgacgtgat ttgaagagat tttcgaagag tataaaacac tgttttgagg
     2221 tggtggataa atcggctggg taaaaactca atctcaggag aaaatgaagt aaatctcccc
     2281 acaactatag aaaaagattt gattctgctc ctcacacaat aaaatctttt tcttttatta
     2341 aaaacgaatc gtttcacgtg ttttctcata tgaggtaaca aagcgattgg ttacaccagg
     2401 ctctgccact tccaatgctt gagaaatctt gtcaaatgaa gcgtgataat caaattcttt
     2461 ttcaaaaata tctaaagctt cgttaaatgc ttcttgaatg cgttcatcaa atgagcgata
     2521 gcggttagaa tattgcaaga gttgctctgt caaagttgca tattgtacaa tattataagt
     2581 ttccgtttct aaagcttcca tatcattcgt tgcaatttca agaactcggg taacagattc
     2641 aatgttaatc attttttgtt ctaactcaac cattaaatcc tcggtattat tgcttgccgt
     2701 aaagaataac ttcaagaaag tttgtggaat acctggcaga ttgcgttttt ccatgtatcg
     2761 cttgatagta tggagacgat tgacataaac attggccttt tgacgtgcat taatatcatc
     2821 tttctcaatt tgtgtcaggc gctcactaac tgaaatttgc tcatcttcaa tatcttttag
     2881 ttgagtttgt aaatcctcaa gattttcttc aagaactgaa taagcttggg ttggttcttc
     2941 ttgatttgaa gttacctcaa caatagctgc ctcaaaactc tctaattctg tctgaatacg
     3001 acgaacatgg cttgcagctg tctcaggaag taaataggtc ttgttcaaac gtgcaatatc
     3061 ttctcccaat aaagtattat tctctttcat atgttgaagg taagttggaa gagttgcaag
     3121 tagattttcc actactttct gagcagcaat ttctcgagta aaaatatcat acaaggcatt
     3181 gatttcctct tgtgcctgtc cattctcata ttcggcatta tccaattcca actgacgaat
     3241 attctcttgg tttttcttga atgcttcata aagcaagtgg aaacgcgctt caatatccgt
     3301 ttcaacaaaa tgataattag catcaattag tttacgataa ccggcttcca aatcctgtaa
     3361 ttgatctggc aattctgtag aaagcgtcgt aaccaaggct ggaacacgat ccacaatatg
     3421 acttaaggcc aaaatgtgat tttctgtatt atccaaaatc actgcggctt ccacagggtc
     3481 acccgatgaa ttcaaggtta caaattgtga aaattcagat tggatatttt ctaattgttt
     3541 ttcaatttca tccaaggctt gaccatactg ttctgaattt tcagcaactc tatgctgaag
     3601 ttcctcaaat aaatccaaag catgaagaac acgaccacta tttttagatt cttgcttctc
     3661 taagtctgcc aaagcattgc gaattgccgc aatatcttct tcaatcaaag taatttgact
     3721 ctcaatttgg tcaatttgat gactggcctt gagaaaacga aatgaatggt tatagccttc
     3781 tgcttcaaag agattatttt caatatcggc aaaagagttg agagataaat cgacccattt
     3841 ttgattccat tcacggaaag ccacttgact ttgtccaatc aagtgcatat tttttacagc
     3901 ttctacttca tcatttactg gaagattgta tagttcttct tttctttctt ctagcgcctc
     3961 taatctcccc tcgtttcgct tacgtagaaa gattgccact acataagcca gaactaaaat
     4021 gactgcaatt gcaaccatta aataaattag ttgtccatta gacatatcaa actccttttt
     4081 tacttgaaac aatcgtaacg attatatcat attttttaga ccaagggaac tacttctccc
     4141 tattttttag acatcaagtg tactatagac agcattttct tcgataaact cacgacgagg
     4201 ctctactcga tcccccatca acatatcaaa gattttatct gcttctgcag catcatctac
     4261 agaaactcta gccatcaagc gatgttcggg atccatggtt gtttcccaca gctgatgatc
     4321 gtccatttca cctagcccct tataacgctg aatagtcggt ttggtacgac cttcactata
     4381 acaggctaaa gcttcttgga gtttgatttc ttgatctgca cccggctgga tatattcttt
     4441 aatctcgctt ccaaccttga caccatagat tggtggttgg gcaatataaa cataaccagc
     4501 ttctaggatt ggtttcatat aacgataaat caaggttaaa agaagggtac gaatatgggc
     4561 tccatcgaca tcggcatcgg tcatcaaaac gagtttttgg taacgggctt tcgaaacatc
     4621 aaattctgcg ccaaatcctg ttcccatggc tgtgaaaaga ctacgaattt cttcgttagc
     4681 tagaatctta tccatacttg ctttttcaac gttcaaaatc ttaccgcgaa ttggaaggat
     4741 agcctgaaac tcacggttac gaccagattt ggctgatcca ccagctgagt ctccttcgac
     4801 gatgaagagt tctgtttcag cagggttatt agaagaacag tctgctagtt tccctggaag
     4861 gttggaaatt tccaaaccag attttttacg tgtgacttca cgcgcacgct tggcagccac
     4921 acgagccttg gcagctaaaa tccctttttc cacgatacgt ttggcaatct gtggattttc
     4981 catgaggaaa tcggagaagg cttcactgaa gaggcgattg gtaatcttga ccacttcgct
     5041 atttcccaat ttggtcttgg tttgtccttc aaactgtgga tttgggtgtt taactgagat
     5101 aactgcagtt aatccttcgc gaacatcttc ccctgttaaa ttatcttcat tgtctttcag
     5161 taacttattc ttacgagcat aatcattgat aacacgagtc agtgccgtac ggaaaccttg
     5221 ttcatgcgtt ccaccttcat gggtatgaat attattggcg aaactcatga cattttcatg
     5281 gtaacctgtt gtgtactgca tggctacctc aactgtaata tcatccatct caccgtctgt
     5341 atagattggt gtatcaaaga ttacatcctt gttctcgttg atatattcaa cgtaactagc
     5401 aatcccacct tcataatgat aatgcttggt ttgttccaaa ccttggcgct tatcagtgat
     5461 ggaaatttga agaccgcgat ttagaaaggc caactcttga atccgtttat ttaatttatc
     5521 aaaatcaaag attgttgttt cagtgaaaat ttctgggtcc ggtgtgaagt gaaccgttgt
     5581 tccagttcta tctgtatccc caaccacctc aaggtctgca acaacatgac cacgacggta
     5641 ttcttggtaa tgaatcttac cgtttttatg gacatgaacg tctaattgag tggaaagggc
     5701 attaactact gacgacccca ccccgtgaag accacctgaa accttgtatc caccaccgcc
     5761 gaactttcct ccagcatgaa ggactgtaaa gacggtctca acagcaggac ggcctgtttt
     5821 ttcctgaata tcgactggga taccacgccc atcatccaca acagtaatcg aatcatctgg
     5881 ctcaataaaa acttgaatat ggctggcaaa tcctgccaag gcctcgtcaa ttgagttatc
     5941 aacaatttcc cagactagat ggtgaagacc ttcttttgag gttgatccaa tgtacatccc
     6001 tggacgcata cgaacagcct ctaagccctc taaaacttga atttgactgg catcataatc
     6061 ctgtgcctgc agatttttga tttcttctgt catcttattc ctttttctta tatgtctaat
     6121 acttgtctta aattcacgat actggtaaac aagtgggtat caagtcctgc agcttgacct
     6181 gcttcgatat caatcggccg atcaccaatg acaagaccag agctaatctg atacttttct
     6241 cttaaataaa gcatggattc gggatttggc tttctcttaa agcctgagct agaagtcacc
     6301 acttctgtaa aataagctgc tatagaggtt ttttctaaaa tttccaaaac ctgatcattt
     6361 cgatgagaga ccaaaaaatg acggccacct tgatttaaaa tgtcttccaa taggtcagaa
     6421 actccttcaa ataaaatcgg gtgttcaagc tctctggctt cattttcctt gtacttttct
     6481 aaaaaattct ctaaattggg agcgaatgtc tcaatcgcaa aaggagtaga aacctttaaa
     6541 gcttgataga cactgtcatg gtcttgtgtg ataccataca gtgccaatgt ttcaacaaat
     6601 gcagctgttg aagtttcata attatccagt aaagttccac ctaaatccca gatgtaatcg
     6661 tgatatttca tacccttcat tatagcattt ttttatgaaa aaagcgatga tttccctgag
     6721 ttttccacat aaaaaacgag agaataactc ccgttttact gatttttacc aaagacatct
     6781 cgatagagca ttcctgttcg taaactctct gcgtcccctc ctagttgctc caccaactcg
     6841 taggcaaagg caagggctgt tgaaggaccc cgactggttg tcaactgacc atctaccact
     6901 actgtttcct tgacgtagtg accatcaagg atttgctctt gaacgccgtc ataacaagtg
     6961 tatcgcttat ttttcaatat ctctgcttga ttgagggcaa ttggtgccgc acaaatggct
     7021 gctagtttct ttccttcttg ctcgaagctt tgcaattctt gaatcaaggt ctgattatca
     7081 cgtaaatgtg cagaaccagg catacctcca ggaagaacaa tcatatcata gtctgataaa
     7141 tctccatcaa agacatgatc tgctcttact tggattgcat gcgaacccgt tacttgctct
     7201 tcaaaaccaa ccatatcaca tgtgatattg gctcgacgca agacatctac aactgtcaag
     7261 gcttcaattt cttcaaagcc ctgagctaac ataactgcta cttttaccat gattttctcc
     7321 ttatttaatt tgttttaata caaccttttt ccgtttgaat gggacttttc cgctcttttc
     7381 ttcagctaga ttagtctggt aactcatcga taaaagcaaa ccaacaccaa tcagattact
     7441 gataatagct gatccccctt gcgaaatgaa aggcaaggga atccccgtca aaggaagtag
     7501 tccagtcaca gcaccgatat tctcaaagat gtggaagagc aacatcataa tcaaacctgt
     7561 ggaaatataa gtgtagaact ggttatttga tttaagagta atcttcaaca tacggtaaat
     7621 caacatgaga tagagggcaa taaccaggac agagccaata aagccaaaat cttctgcaat
     7681 aaccgtaaaa atcatatctg actctcgaac tgggataagc agattcgaag cattaaatcc
     7741 ctgaccaaat aagccaccac tcccaatggc aatctgccct tgagcctgct ggtaagtcgt
     7801 tgtttgggca aactcaaagg gattgagcca agccaaaatc cgattaattt ggtaggtcgg
     7861 cattccaatc tggtgaagaa aagctcgtcc gtccttgcta ataaagatag ctaagaaacc
     7921 agcaactcct gttacagcag tcacaaatac tgggataata attttccaag aaacccctga
     7981 taataaaacg attcctgaga aaatggctac aaaaaccaaa gccgtcccca agtcactttg
     8041 aagtgctaaa agaactagga ctggaatggt aaagagaatc atccagaaaa ttaacaaaaa
     8101 gtccagcgga accgtgcgtc tccattcctt atgtttcttt gtaaattgga caatgacacg
     8161 agccaacatg aggatatagg atatcttcat aaattctgac ggttggaata gggtaattcc
     8221 atttattgat acccagtttt tggcacccgt tgatgcaact aagcttggat tataaaatac
     8281 aatcggcaag atcataagtc ccaagcctaa aatatataga aagggggtca ccttccaaag
     8341 aaattctgta ttaaaaagca tgaccacaaa accaatcaca agccccaagg caatccaggc
     8401 gacctgctgc cctaaaatgg gcagaatatt attgggataa tcatgactaa cggctatata
     8461 gatagccacc acaccgatga ccagtagaaa aaatactggc aagagcaaac tgtaatcgac
     8521 tcttgagtcg agagaacgtt tcatatatac taaccttata ctttcataca atactattta
     8581 tcaaagttca ttaaaaaatc tatcaatagc ctcgtcaact tcggatcgag agatggtttt
     8641 aacagtcgct tcttctgcta gagatgctac tatttgtttg ccgtatcgtt ttccgacgat
     8701 tctcctatcc aaaataagag ttaaggaacg ttggtattca cgtctcatac ttcttcccaa
     8761 agcctgtttt aaacgaataa tggccattgg caattgataa tcataaaagg catttttccc
     8821 ttcttgattc agttcttgat taatcttttt cgtcaagggt tcttgaggat tttggaaagg
     8881 aagcctcggt acaacttgaa tcacaaaagg atggcttgaa aaatcaactc cctcccagaa
     8941 acttgctgca ccaagcaaga tttgttgttc acctttttca aagcgtttct ttagctgatg
     9001 aacatcccca tttttatact gtgtcaagtg gctaactgta agtaaatccg atactgctag
     9061 aagcatgtct ttagcggtaa agagaaccaa aatcggttgc tggaaagctt gaatttccac
     9121 tagtaaagca gctacctctc tggcatagac ttctaaggag gtttctgtta ccagagggaa
     9181 atctttgacc ataaccactt cttgttcctg ttttccccga gattcaatct tgacaaattt
     9241 ggcttcagga tagcctaaaa ggtctgccaa agaaaccctc tgactaatct caagagtagc
     9301 cgatactccc aagacttggc aactctcagg aagtaaagag gacagaagag tacggcctga
     9361 ttttgtagaa gaaatctgaa ttttcttttg actcgtttca gttacttcaa gccagtaatc
     9421 accttcagct gtaaaatagc gaaccagctc atcaaagcct tctacttcta attctgaaaa
     9481 atactgatgg agattatcca gagaatctaa gatatttttc ctagatttgc cagactgaaa
     9541 ttgttctatc aagtagagac actcaaagcg aatactttct agtatccgtt gttgaaccct
     9601 gttttcttct cctactaaag ccttatcaat taaatcgata atagattgta tatcgtaggt
     9661 ctcttgaagc agattttcta gagctaacaa aatcttttgg acttcatcaa taatcagtaa
     9721 acggtcactg acaaattcag gattatcttc aagtctggtc acgagatagg catgattagt
     9781 cactaaaagc ttgcaagtct ctgccctttc ttgactacgt ttccaaaaat cttccgtcac
     9841 aaataagctc tgggatgata aattcccatc atgacgaagg tctgctagaa aatgttggta
     9901 acggtagagt tgcccgattt catccaaatc tcctgtctct gtctcagtaa gccagaccaa
     9961 gacttgcatt ttaaagcgtc taaataagcg attttcatca ttttcctgca aggaatgata
    10021 aaaggcatcc aacttcagat aattttgtgg tccctttaag ctatgaatat ctgtatggaa
    10081 cacttccttg agacgtttac cttcttcttc catgatttga ttttgaagaa tctttgtcgg
    10141 aacactaaga acaatttgtc gctctttgga ttgagataaa gcgggtaaga gatagccata
    10201 ggttttccca atccctgtcg gcgcttgaat cagagagaca ggttcatctt tcaatagcaa
    10261 gccaacctct ttagcaaaac tttcttgttc ctccctcact tcaaggttca acagagaaat
    10321 atttttagaa aagtcttgag atagttttcg tagctccaga gaagctgccg ttttcttaaa
    10381 atacagacct tgaacttgga ccaagtctgg agaactcagg atagattggt tgcgataagt
    10441 ttcctcaata accaggtagg actcatatag gagagcgtca gccatttcca gcaagcgttc
    10501 caagagaccc ttaggaagct gggtcatctt ttcccgtaaa aaaagaagta attctgctgt
    10561 agcttgggca tctgaaaggg ctgtgtgtgc gtgtttaaga ggaattccta attctcgaca
    10621 caaaatcggc aagctatatt tttccagttc agggaaaaag acctgggcca attcgaccgt
    10681 atcaacacga gggtttctta gctcatagcc ttcaaaaaat aaattttccg ccaagagatt
    10741 agcatcaaac tgaacattat gggctacaaa aatcccatcc tccaccaagt caaatatttt
    10801 tctggcaact tgcgaaaaat caggtgcttg cgccagacgt tggtctgtca atcctgtcag
    10861 ttctttgata tgagcatcca agggttcatg tggattgaca tccgtcgtat agtgatcgac
    10921 gatttctccg tcctcaatca cgacaattcc cacttggata attttagcct tactacctgt
    10981 gctagttgcc tctaaatcca ccacaacata gcgattacca atcgttttca ttataaaaaa
    11041 ttataccaaa aaaagggcca tttggcacct gcaaacatag gataattttc aaactcaaga
    11101 acactacttt tcttaaaaat cccatcgaat agagcattct agcctgctga tttttataaa
    11161 atagtgaaga aatacgaaaa attgagagaa gaaatgtttg catcttcctt ctctcaacga
    11221 atcatgtatt ttatctaacc atgtcaggat cgtagtcata aaatcctgta tcaaggaaac
    11281 ggtttttagg gtgaagttta cgaacttctt catccagcaa gaaggcttga tcatggctaa
    11341 agttgccctc ttgaatcaag ttacgcgctt ggataaagag ttttgcaatc tcaacaaagt
    11401 tctgaccagg agtgtagagc ccttctagtt tccagcgagt aaagccatgc tccaccaatt
    11461 ctgttaattt gatcatcaaa tcaaggtcat tgttggcaaa gatatgggtc ccatgattat
    11521 cttcaaaaat ggaatagtgg ctctctggat cacttggctc agccaagaag aggtcacgtt
    11581 tatgcgtctt ttcatcatcg atatgtgtaa agttatagta gttttgcaag agcggacgtt
    11641 tagaatgatg gatgacacta gcaccgtaaa ccaaaacttc agcaggaatt tccaaaattt
    11701 ctggcatttt gaaaagttca gctgatggaa tttcacgcgc caaaacagcc tcagatgcgc
    11761 cagccttttg tccccagaag ttaatctgac gactgctagt taccatggtt gaagcatcgt
    11821 agatggtctt aaatgaataa ccatcgcggt taactacgta aaagacgcct gcatccccaa
    11881 tcgtaatata gtctgtcttg atttcttcca agaagtctaa gaaaggcttg atacggttca
    11941 tcatatcttg gtgcatgaga gcattgaccg caacgatcaa ttccttacca gcatcatgaa
    12001 ccaacttagc gatttcacgt aattggtcat aactaaaggt cgttggcaga cgaaggccaa
    12061 aatctttctc accgacatag atacggtcta cgccagcttc gagtagttgt tcaacttgtt
    12121 caatactttc agcagttgct gtaatgacaa tcttttccat aagaaaaatt ataccacatt
    12181 tctccaaaat cagccatgct ttgaaaatga aaagggactt tattcttttt gtaacctttc
    12241 tgtaataatt ctctgccgaa aaaatgataa aataggtatg tactgttaag gagagaatca
    12301 tgcccgtaag aaaattacaa tcctatgagg tagactatca agaagaatta aaccagcagc
    12361 ttcctcatta ccaagcttat acacctgaag cgcaatctga tgccaatctc aaggaaatcc
    12421 tattttttat taatatcgct gttttttgta tctgtattgc tatctttagc tttatctttt
    12481 tggcattaaa attatcaact gctcttgcct ttgccgcagc aatcggattc agcttacttg
    12541 ttttaaaagt tcaacggtct attatcaaac gaaaacgtag aagataaatc caaaatatcg
    12601 ccccaattgg agcgatattt ttattttttc tttttagatg gtgtctgaat ggcaatcttc
    12661 acttcaaaga ttgttccctt gggtttatta tctttgacag taacagttcc ttttagagca
    12721 tctacaattt gcttggctag ggataatcct aaaccaaaac cacctttttg ccgggttcta
    12781 gccttgtcta ctcgataaaa acggtcaaaa attttctttt tatcttctgt cgaaataccg
    12841 attccattat cagaaacaag taaataaaga ttgcgatcgg tcgccgagat aagaaaatca
    12901 atttcaccat cctcctcagt atacttgacg gcattatcga aaagaatggt catcagttgt
    12961 ttcagaagaa gctgatctgt gacaattgtt cgatggatac gattttcaaa acggaagaca
    13021 cgattatttt ccgaagcaat catctcgtag tttgtgaaag ttgtattaaa aaagctagtt
    13081 ggaacttctg caagctccgg cttaatccca tcatctctcc gagctaagtt cagcaagctt
    13141 gtcgttaaaa aacgcatatt tcggacttct tccaaactcg atgcaatgct ttcgctcaca
    13201 tccataatgg tagcttctgg cttacgaaaa agggtctcta agcgattttg caaaactgcg
    13261 agtggagttc gtaactcatg actggcattt tccacaaaag actgttgctt ctgcatactc
    13321 tcaagcaggg gcctaacact gaccctagct agatagagac tggcaagtaa agacaaaatc
    13381 cagaaactag ccatcacgac cacaatcaat tgctcatgct tttgactagc ctgctccaac
    13441 tgactggtat taatcaagac agcagcatac ttgatattgg ttgaaaccga actaatattg
    13501 gtctccatca aaatcacacg atagatttct tcctgcccat agctattaaa aacctgaatc
    13561 tggtagatat gtcctagttc tttcttttct aacttaatct tatccaagcc caaaaatcga
    13621 tttccagaaa gaagttgagt aaagtcttta tcaaagagaa tgacttccgt attggaactg
    13681 acattaggtt ttatttctac tttactagcg tccgccctag cattttctaa atctttaatc
    13741 tcttctgttg ccctatttat agccagctga ataactgctt gaggattttc actcagtcca
    13801 tgaagcttat cgtccaccga agtataaaga ctcgaatgca tgacttgtaa aataatcaga
    13861 gtcattgtag aaaaaatcag ggtgaagaca ccgaagttgc ggataaaata actaaagtca
    13921 tccgcatacc atgttttttt aagtttactg aacatctttt aaaagatacc caacactacg
    13981 caaggtttgc aaattctctg caaaagtggt tccctttaat ttcttacgga cttttgaaac
    14041 atagacttcg acaaccgaaa tcgttgtatc actatcaaat ccccatagac ggtcaaaaat
    14101 ctgcgtctta ggcaaaatca cattttgatt ttgaaggaaa taaactagta aatcgaactc
    14161 tttccccagc aattcgacag gagtatcttc aactttaacg gtattggttg ataaattaac
    14221 cacgatattc ccataagtca aggtgttttc attaaacttc cctgaacgtt tgagaagggc
    14281 ctgaatccgc attttaagtt cttctaggta gaaaggtttg gtcagataat catccgctcc
    14341 cagttcaaat ccatgtccct tgtcatccaa actttccttg gcagtcataa tcagaactgg
    14401 tgtcgtaatt cccttttcac gcaattcttt taagacttgg aaaccatttt tttctggcaa
    14461 catcaaatcc agcaaaatca agtcatagac accactctca gcttcgtaga gaccttcttc
    14521 tccatcaaat acctgcataa catccgcaaa atcgtctaaa aagtcaaata ctgaatttga
    14581 cagacctagg tcatcctcaa ccaataagat ttttatcatg agaaactcct ccttattaaa
    14641 actattatac caaatttgcc ttaaaaaaaa ctcaactctc tgcattttac atgagatagc
    14701 tgagttttct ttttatttta ggcttattta tgcatttccg tattgaagaa caactgcttc
    14761 gactgcagct ttttcacggc taatcaagtc aacacgcgct gcaatttcct tgattcccat
    14821 accgatgtta cggctaagag caaggtcaga aagttgcggt tcaaagaact ccttgtattc
    14881 cgccaagcgt tgctgagtct taaatacatg agcaggaagg ataacaaagc tatcaaagct
    14941 catatctcct ccaagggctg ccttaatcca agcccagttt tcacgcgccc aagaccaagc
    15001 tgttttctga gttgcttgat gagctaggaa ttggtaatac caagcagaca agtcctgtgg
    15061 tttgaccaca aatttgtcct tccaagaagt aatcaagttt tggatattat ccgcatctgt
    15121 actgtatgca agagctgctg ccaactggcg tttaaagaca gcatctgttg cgtgagtata
    15181 agtatcaaga taaagtgcta acaagtcttt agtctcatga tgtttcatct cattaatcag
    15241 aacttgtgaa cgaatagctg ctgggagtcc tgcaagattc tccttgtgtg ttgcgaagat
    15301 ttggctagcg acttgactag cttctgcatc atttgagaga atcatcatcg aaacagccag
    15361 ctgacgaacc aattcatcct catctgattc tccgtcttta gcttcaaaac caagacggtc
    15421 atagttatga cgagccaatt tagcaaccag tcctttgaag gctgtttcag catccgttcc
    15481 ttcatcaata aagcgctcaa gggctgaaat cacttgagaa acagctgaaa ccaccagata
    15541 agactcttcc ttagcaagtt tatcaagaac tggaagcaag tctgcataag aaatgtgccc
    15601 tgcctcagcc aacaaacgac gttcttgaac aatttgcagt ttgcttgtgt tatcaagtgt
    15661 ctctagctca gcaagaacag cttctaacaa gtctccttga tagtcggtaa tatagtgggc
    15721 agtattttca gtgttgagac gaagagctcc ttcattctca gcaagaagag ctgcgtagcc
    15781 agggatttcg atactttcag tttcgagtgt atcaggcaag cctttccagt tgctattgag
    15841 gggcaccacc cagagacggt tcttgtcttc gttctcaccg atgaagaatt gtttttgtga
    15901 aatcttcaag acatcatttt caactttgac agtaagaact gggtaaccag gctgttccaa
    15961 ccaagaatcc atgaaggctg cgacatcacg tcctgacgct tgaccaaggg catcccaaag
    16021 gtcactacca atggtgttgc tgtattggtg tttttcaaag taggcatgca aacctttagc
    16081 aaaatcagca tctcctagcc aacggcgaag catgtgcatg agacggcttc ctttggcata
    16141 gacgatagcg ccgtcaaaga gtgtattgat ttcatctgga tgtttaactt cgacgtggac
    16201 agactgaacg ccatcagtag cgtcacgttc aagagcaaga ggtactccac ctgtttggaa
    16261 atcttcaaag atattccagc ttggttcgat ggtatccaca cagacgtatt ccatcatatt
    16321 agcgaaactt tcattgagcc aaaggtcatc ccaccatttc atagtcacga ggttcccaaa
    16381 ccattggtga gccaattcat gggccacaac aagggcaact tgttgacggc tagcaaatgt
    16441 agagttctca tcgacaacca agtaaacttc acggtaggtc acaagacccc agttttccat
    16501 agcaccagct gagaagtcag gaagggcgat gtggagagat tgaggaattg gatacttaac
    16561 tccatagtaa tcttcgtaaa actcgataga gcgaacagcg atatccagtg agaaatcaag
    16621 atttgaaagt ggatgtgctt tggttgagta gacacctacc agggtaccat ttttagtttt
    16681 agcggtcacc ccttgcaaat caccagcaac aaaggccaac aagtaagaag acatgcgagg
    16741 tgttgtctca aacttccaga tacctgtttc cttacggttt tcaacatcga tttctggcat
    16801 gtttgacaag gccaattcac cttctgcttg gtcaaagcga agagagaggt caaaagttgc
    16861 tttggcttca ggctcatcca cacatgggaa agcttcgcgc gcaaaatggc tctcgaactg
    16921 agtagacaag acctccttct tgactccatc aactgtataa taagaagggt aaatccctgt
    16981 catgttgtct gtaattttac cagaaaaggc aagaaccaat tcaacttgac cagcctcagc
    17041 caattcgata tgaagggctt cattgtcatg gtcaactgta aatggacgag cttgacctgc
    17101 aacttctaca gaggtgattt ccaagtcttt ttggtggagg gagatgcggt cactctgtgc
    17161 ttgaccagtg atggtcactt tcccagaaaa agtcttggtc tcacgactca aatctaaaaa
    17221 taaatcataa tgttcaggaa caaattgctt aataaaatgt tcaactgctt gcatagtttt
    17281 ctcctattct aagtttaaga gctgctgctc ttcttcaaac aaacttatta tatcatattt
    17341 tgcttgaaaa aaaaggattg gacagcgatt tccaaaactt tcttccttct aatagtctac
    17401 agtgggtaga ccttgcgaaa ttcttctaaa acaaccttgc tttcagatgt aaaagtcagc
    17461 cctacttcac ccaaacagtc tgtgaaaaag tcctcatgaa cctggcgcca ataggcaagt
    17521 gatttgtctc cctcaccttc cttaaaggca tgttgcgcag aaacttgatt gaagagttca
    17581 acagaaacct ttgtaatttc gacaatgcag acagactgat tttgactatc taaaatgaca
    17641 tcgaaggtcc ctacttgggg aagtggttcg tcttctagta catagaggtc ataggctgat
    17701 gctgttgctg tcttttctcc tttaaacacc aaatccgcta aaaggtctgg ttcaactcca
    17761 aaagcccaag catcgatttc atctccgatc aaaggattga tttgcttgta tttattccac
    17821 atttcttgcg gtatcatggg tactcctttg taatttttta ctttcttctt ttatgtgttt
    17881 aagatgatct ggatggtcaa tctctaaatc aaaaatctct ggaatagaac tgtagtggat
    17941 aatgcacttg atacccaact gattcatttt ttgtatgaaa gaagtattca gatagcctgc
    18001 tacagcaaaa ttaatcttgt tctttcttgc tttatcctgc atatctctta gcatatctaa
    18061 cattattgga ctttccatat catgccattg actgtttctc atagtcgcaa aaacaaagga
    18121 agtcaaatca ttcattccaa ctacaatctt tgaaatgccc gtttccagta tactagataa
    18181 gtcaaaatac gctgacggta attcaatcat cgttccgact ttcccagtaa agccatactg
    18241 acgcaatact gtaatagctt gttttaattg gtcggcatca ttgacaaaag gaaagataac
    18301 agatagattg gggttggttt gataaacttc tgtaacgaca tgtgcttcag cctgaaattc
    18361 atccaaacac gccagtaaac gcctggttcc tctatagcca aacaagggat gcccttcgtc
    18421 aaaaaactct ttagtcccca ctaaacaatt ggcttctgta ttcgttaatt cagtaaaacg
    18481 ataccaaact tcttcatctg agtacaggga gcagatagtc tctagataat cttttacaaa
    18541 ttgctgacaa cttgctaata tgatgttttg attaagctct ctcaacaaat attccccacg
    18601 aatcatgccg acgtggtgaa atagttgagg ataaattttt tcaagaattt tttcgccact
    18661 aagggcaagt tgatttctca tagccattca cctcatctta aaagatacaa tatcatatat
    18721 aattatatca aaatttcctc tagttcaaaa gcttcataag gttcagataa ctcatatcct
    18781 aaaaattctg ctactttttt ggaagcctca ttatgagcat cccaaagtgg aaacatatct
    18841 ctatttaaac tatctagaat cattgcagca ccaagctttt tagcaaatcc atttccttgt
    18901 tcgtttggtc tagttgcaac ttccacttca actgctttac ggtaaactaa ccctgaggaa
    18961 atcccagcaa tcagttcatt atttttaaga atcacaaagc caaatccacc ttttaaaaca
    19021 aaatcctgat aggactcaaa atccccctgt aaatcctgtg accattcttc cgtagaaaag
    19081 cagttataaa tatgattatc aataggcaca atattgtaac cttcctctaa atgagtaact
    19141 agattattta aaaattcaac ttgaaaattt gccttatctt taaaagaata gcgagtaaaa
    19201 gaatttagcc ccacttttcg atgcagaaaa tcttgccaat tagtattttc tgaaataata
    19261 atcttataat ctaaaccata ttttctaaca aaatcttccc aaaatctgga atccaactcc
    19321 cctgctaggt atagaaaatt cccaacatca taaaagcttg ttgtcctatc attgtttcgg
    19381 tagacagttc caatttgaga tttaagacca tagagaacca tatttttctt ccatgtttta
    19441 aatagttcca ttatccctct acttcacctt ccaattcatg taagaagtct tgtccagttc
    19501 tggaaatcct aataattcag acttaacctt caagactaat ggcgatgcat tttcttctgt
    19561 aatctcttga atatccatcc aaatatatcc aagtgaatca ttcgcaccat cagacacagc
    19621 ttccgaagtc gtaacttgag gtgcactctc attcatttca acatcataca aggccatgac
    19681 atggtgaacc ataaaatttg ttaactcttc tctgacgaaa acatcgtaga ttcgaggatt
    19741 agagtagctt ctaacagtaa atcccgtctc ttccataact tctctagtca gcgtttccgt
    19801 cagtccttca ccaagttgct gactgcctcc aggtagatca taccgatgtt gataagggcc
    19861 tctcgttttt tcaatgcaaa gtaactttcc attttcaaag caaacacagt agaccccaaa
    19921 gtgatttttg atttccatcc aactcctcct acttcaaaga ccagccacca tctattgtca
    19981 agatttgtcc ttgcatggcg ctcgcttttc cacttgctaa aaaaagacta agctctgcta
    20041 tttcctctgg ctcaatccag cgcttgattg gggtttcact agccacccag tcagccaaac
    20101 cacctggttc aaaatccgca gcggtcatag ctgtcttgac tgctcctgga gcgataccaa
    20161 agacctgaat cccagcttca gcatagtcta gagccaactg cttggtgaag ccagccaagg
    20221 catgcttgga tgaagtatag gcgtgaccac ctccacctgc taggctagaa gcaatggaac
    20281 acatattgat gatgattccc tttttatttt ccagcatttg tgtcaaataa taccgagtca
    20341 actctactgg aataatgtag ttgatttcaa aaatctcttg aatgtcctgc gccgtttgtt
    20401 ccaacagtgg tttgtaatca tccaaaactc cagcagtatt acacaaaaca tccacctgag
    20461 ggcaccagtc aaaaataggt tccaagtcca aggtcaaatc tctctgtaaa aagtgaaaat
    20521 caccctctaa gagtggcttt tcaccttggt caactccata aacttgatag cccttctcta
    20581 aaaagaggcg agcttgagcc aatccgatcc ctgaactcac tcctgtaatg agtacacgtt
    20641 tagtcatgca cttctaccca atccgttgcc aaaacatcac aaactgtcgg gctccacatg
    20701 gaaaaacctt ctccttcgcc agaaacgttg attaggaaat aaggtgtcat ttcaagtgca
    20761 agcccatttt gctcgatggt atcaaagagt tggacatagt tttccgcacc tccccaacca
    20821 gttcgtacat attttctctt agcctttaac ccaggcagga tctcttcaaa tgtcatgttt
    20881 ttctccttta attctacatt cttcatttaa ttatagcaaa aaaccgcttt atacggcttt
    20941 ttgaatgtga gttattcaaa cctgctacta cttacggcaa attattccct gcagcaagat
    21001 aaatttcata ccattctttt cttgttaagc taaagtttgc cgctcggcta acttctctca
    21061 agtgcttagg atttgttgta cctacgactg cctgcatttt tgctggataa cgcaatatcc
    21121 aagaaatggc aatagttgaa gaggttactc catatttaat agctaaacga tcaagtactt
    21181 gatttaaagc ttgaaatttc tcatttccaa caaaattccc tttaaaatac ccgaattgca
    21241 agacagacca tgcttgaatg accacatcgt gtaatttgca atattcaaaa atgctgccat
    21301 ctcgcatagc tgcttgacta tcttccatat taacatgaaa agctgattca aatcctggag
    21361 taaaagccgc actcaattgt agctgattaa cagctaacgg ctgcttgaca tcttttttaa
    21421 gcaactccat catcatagga ttttgattag aaactccaaa atctcgaact ttaccttgtt
    21481 tataaaggag atcaaaggct tctgctactt ggtcagattc catcaaagca tctggtcgat
    21541 gaaggagcaa gctatctaga tgatcaatct tcaatctttg caaaataccg tctactgatt
    21601 ttataatata gtccttagaa aaatcaaaat aggtaaattc ttcaatgcga atgccacatt
    21661 tggactgaat ccacatcttt tctcttaaat ctggacgatt ttttaggaca agacctaaca
    21721 gttcttcaca acgaccacga ccataaatat cagccaagtc gaaggcattg attccaacag
    21781 aaagtgctgt ttctacaagc tcttcaactt cttttacaga cttatctttt attctcatca
    21841 ttccgagaac aatttctgat aattctttgt catcttgacc aagagttatg tatctcatca
    21901 aatttttctc ctttaatttc taacattctt cccttcatta taacaaaaaa acgctttgca
    21961 acggcttttt gactatactt cactccattt tatcttctta aacccacgga acaagagaaa
    22021 aatgccaata aagaggacag ctaaaggaat aacttttgta aggaaaacat ttgaaattcc
    22081 catccactca taataacgga gcagagaacc caccacaaga tgggcaataa tcatactgac
    22141 aaatggacga aagaccgctt ctttccaatt ccaaataccg ataactagcg aaatcgtaaa
    22201 gacagacaaa ctatcccagg gatccggaat ataaaaggct ccttcttgta tgaagcttgc
    22261 cattcctaca tatcctaaaa caactagaag aactatagtc ccaacaacaa tgtaagtgcc
    22321 aattttcatt ttaggagaat cttggactaa acttcttcgt aaaattgtgg ccacaagtcc
    22381 aaatccaatc agaaaaataa gaagttgccc taaaaatgtg agcaaattga ctgttaagag
    22441 aggaccttta gaaaaatcac ttagtagttg ataataacgt aataccgcca ggacaagaat
    22501 tggcgtcaaa agggactctt tgatagaact gcgaggtgct cccttgagaa tctctttcat
    22561 tattttttta ggattcttac ctagataatc ctctgcactc atgccatctc gttctgcttc
    22621 tgagaaatct agcatcatca aatagatctg ctctctgaga tagtcttcat catagagaaa
    22681 tccagcaaga ttaaaacttt cccacaactc ctcaaaatac ttttgattct cctcagaaaa
    22741 ctcatgtagc aaagcgcttg tttcttcgta atacttcatt ttcttcatgg tttaaccccc
    22801 attcttaatc ccttctactt tttgactcaa atcgtcccat tgttgccaaa agactgagac
    22861 acgctcttct ccttctttca ttaatgaaaa atacttccga tctggaccat ctggcgacgg
    22921 gcgcatgtcg cctcttatcc attgattttt ttctaacttt tgcaacaaag gataaatagt
    22981 tcctggaacg atagtatcaa atccagcctc tcgcaaagtc ttaaccaact cataaccata
    23041 ccgctctttt tgaccaatca tatccaagac acaaccttca agaacacctt ttaatagctg
    23101 agtttctttc atcacttctc ccttctaatc tattttgtaa tacctactag taacttcacc
    23161 tatagtatat tacttctaca ctagtttgta aagcataata gttaatactc ttcgaaaatc
    23221 tcttcaaacc acgtcagcgt cgccctaccg tatgtatggt tactgacttc gtcagtttca
    23281 tctacaacct caaaacagtg ttttgagctg acttcgtcag tttcatctac aacctcaaaa
    23341 cagtgttttg agctgacttc gtcagtttca tctacaacct caaagcagtg ctttgagctg
    23401 acttcgtcag tttcatctac aacctcaaaa acatgttttg agctgacttc gtcagttcta
    23461 tctacaacct caaagcagtg ctttgagcaa cccgcggcta gcttcctagt ttgctctttg
    23521 attttcattg agtataaata aaaaaacaga actagtctga actagtcctg tctactttta
    23581 cccaatcaca cttccatttg gtacagctgg atcaactgtg agaagggtta atttgccatc
    23641 atgttcagct gagagaatca taccctggct gacatatttt ttcatcattt tacgtggttt
    23701 gaggttagca acgatttgaa ctttcttgcc gaccaattct tgttcatttg gatagtattt
    23761 tgcaattcct gaaagaatct gacgatcttc tccatcacca gcatccaagc ggaattgaag
    23821 caacttatct gaaccttcta ctttagacac ttctttgact tctgcgacac ggatttcaac
    23881 cttgtcaaag tcttcaaact tgatttcatc cttgtttagt ttgagctcaa cttcgtccgg
    23941 attccattct ttttcgactg ctggtttatt gccttccatt tgttccttga tataggcgat
    24001 ttcttcttcc atatttagac gtggaaagat aggtgttcct ttggcaacta cagtcacatc
    24061 tgctgggaag tcagccaaac tcaagttttc aagactagaa acttcttcca aaccaagttg
    24121 agtcaaaact gcacgactag tttccatcat aaatggttca atcaagtgag caactacacg
    24181 aatgctggct gccaagtggc tcatgacact tgccaattgg tcacgaagag cttcatcctt
    24241 ggccaagacc catggtgcgg tctcatcgat gtatttattg gtacgagaga tcagagtcca
    24301 gactgcttca agcgcacgtg gatagtcaac tgcttccatg tgtgtatgga agtctgcgat
    24361 tgattgttct gcaacctcag caagaacatg atcaaattca gtcacacctt ctacataggc
    24421 agggatttgt ccatcaaagt acttattaat catggaaacc gtacggttaa ggaggttccc
    24481 aaggtcatta gccaattcat agttgatacg gccgacatag tcttcaggag taaaggttcc
    24541 gtctgaacca actggaaggt tacgcatgag gtagtaacga agtggatcta gtccataacg
    24601 ctctaccaac atttcagggt aaacgacatt cccttttgac ttagacattt ttccgtcttt
    24661 catgacaaac caaccatggg caatcaaacg atcaggtaat ttaacatcca acatcataag
    24721 aaggattggc cagtagatag agtggaagcg aaggatatct tttcctacca tatggaagac
    24781 tgttccattc cagaacttgt caaagttacc atgttcgtct tgagcgtagc caagagctat
    24841 cgcatagtta agaagggcat caatccaaac gtagacaacg tgttttggat ttgatgggac
    24901 aggcactccc catgtaaagg ttgtacgaga taccgccaaa tcttccaagc ctggctcgat
    24961 gaagttgcgt agcatttcat taaggcgacc atctggcgtg ataaattcag gatgagcttt
    25021 gaaaaattcg accaaacggt cttggtattt gctaaggcga aggaagtatg attcttcaga
    25081 aacccattca acctcatgac ctgatggagc aataccacca gtcacatttc cagcttcatc
    25141 acggaaaact tctgccagct ggctttctgt aaagaattct tcgtctgata ctgaatacca
    25201 accagagtat tcacccaagt agatatcatc ttgagcaagt aagcgttcaa agacttgtgc
    25261 gacaactttt tcatggtagt catcagttgt acggataaat ttatcgtatg agatatctag
    25321 taattgccag agttctttaa ctccaaccgc cattccatca acataggctt gaggtgtaat
    25381 accagcttct tccgctttct gctggatttt ctgaccatgt tcatcaagac ctgtcagata
    25441 aaatacatcg tagcccatca ggcgtttgta acgtgctagg acatcacatg cgatagttgt
    25501 gtaggcagaa ccgatatgaa gtttcccaga tggatagtaa atcggcgttg taatataaaa
    25561 atttttttca gacataattt ttcctttcca ggcaaatgaa acctgttttt ctaacacttc
    25621 attatatcac atttttaatg aatttcaata gggaaatcca tacaaaaaca agatagacga
    25681 gtgtccatct tgttgatctc attcataacg aagggcttca attggatcaa gtttcgatgc
    25741 cttgttggct ggcaagactc caaaaatcat accaacacta gccgaaactg caagactaaa
    25801 tagggcgact gggattgata ctccaacttc tataccttct attaaacctt gcagtaacaa
    25861 acctgctaag gcagttaaac cacttgcaat tgtcaagcca attaagccac ctaacaaggt
    25921 caaaatcatg gattcaatca aaaactgaat taaaatattg gcacgtgttg cacccaaagc
    25981 cttacgaaga ccaatctcac gagtgcgctc tgtcaccgaa accagcatga tgttcatgac
    26041 accagttcct ccaacaaaga gagaaatccc tgcgatggaa ctaataatcg tcgtcataaa
    26101 actaaacgat tgttgaattt ctgcaaatac aagggactca tctgccacct ggtattctcc
    26161 ctgttgtaag cctgcaagct ctgtcatttt tcgtgccagt tctggaccca gagttggggt
    26221 taaactggta tcattcactc gaaagacaat actagctatt tcatctacat taaaattcgc
    26281 agcaagggag atattggtag taataggcaa gccaccaaac ccatatattt ttgatctttt
    26341 agcctccgga ctagtataaa ccccaatgac ccggtaacta aatccattga cttctacaac
    26401 cttgttaata gcctcttgag gagattcaaa taaactaatg gacaattcct catctagcaa
    26461 aataacactt gcaaactctt tgaaatcttg ctctctcaga ctacgacctg caataatttc
    26521 attcttaaca gcgtccatgt aagttctgtt tccacctgtc aaattagcat tctcaacctt
    26581 tttatcttga taggtcaaga tggcattcgt tgaattggtt acatagtaac tatccactcc
    26641 cttcagttta gctgcctctt ggacccagga ttcttgcggt tttggcggtt caacaggaac
    26701 ttcctcttcc tttccagaaa ccgtaaaagc tgattgtttc tgagtaaaag acccatcttt
    26761 acttttttta ggagagaaaa agacgctaat atttttctga gatttagtca tatctttatt
    26821 gacttgacga gatagggaat cacccaaagc cataatcaca acaactgatg aaacaccgat
    26881 aataatccca atcatagtaa gcaaagaacg catcttgtga gccatgatag atgaaaaggc
    26941 aaatttcaga ttctgcatct tagttttcct cctttcctaa ctgagcactg tcagacgaaa
    27001 tgaccccatc ccgaatgaca atctgacgtt tggcataggc agcaatctca ggctcatgcg
    27061 ttaccatgat aatggttttt ccttctttat tcaaatcaac caataattgc ataatttggt
    27121 tacctgtttt ggtatccaag gctcctgtcg gttcatccgc taggataata gaaggattgt
    27181 ttaccaaggc acgcgcaatg gctacacgtt gcttttgacc accagataat tctgaaggta
    27241 aatggtgact acgttctgtc aattcaacct tgtctaaata ttcctcagcc aacttgcgac
    27301 gttttgaaga cgaaactcct gcgtaaatca agggcaattc tacattttgc agagcattga
    27361 gcttcgatag aagaaagaac tgctgaaaga caaaaccgat ttgttggtta cggaccttag
    27421 ccagttgttt ttcaccaagc ccagccactt cttgaccttc aagataatat tctccactgg
    27481 ttggtgtatc caacatgcca atcgtattca tcagagtgga cttaccagac ccagatggtc
    27541 ccatgatggc tacaaattca ccctcattca cttctagatt gatatttttg agaacctgca
    27601 attcttggtc accattacgg tagcttctga agatattttt tagactaatt agttgcttca
    27661 tcagtcttca cctcttttcc ttcttccaag gaagatgttg gattactgat gaccttagca
    27721 ccattcgtta aaccagaagt gatttcttga ttttctgcgt cagcatttcc caatgaaacc
    27781 tcaacttttt tagccttttg ttgttcatcc acaatccaga cataattttt actatcatcc
    27841 attactagac tgctaacagg aacaagaata gccttagttt tgcttttaac ctcaatgttg
    27901 acagaaaaac cctgtttcaa atcaccaacc tcgcctgtca catcaatagt ataagggtat
    27961 ttagaacctg tattatttcc ggctgctgga ctagctgctt caccattgtt tttaggatag
    28021 tcagaaatat agcttaattt cccagtccat tttttatcag gatacacttt agaagtaaag
    28081 cttacttctt gacctacaga aaggttggct agattgtact cagacaattc tcccttgact
    28141 tgtaaatttt cattgctgac aatatgaacc ataacttggc tcgcccctgt tggagattta
    28201 gaaacattgc tattgacttc gactacagtt ccctctaggg tactgagaac agttgttgca
    28261 tccaattgac tttgagcctt gcttaattgc gccgcagcat ctgcacgcgc atcacgggca
    28321 tcacccaatt gagcgtcaat agaagcaaca gaatttccag ccactggagt tgggctttgc
    28381 accgttgcat cttctcctcc tactggcgct ggtaactgtg gagccggagc tgaagcggct
    28441 tcatttcgtg cttgattgag ttcattgata tgacgatctg ccttagctac tgctcgacta
    28501 gctgaatcat aggccgcctg cgcttctgaa ctactgtact tgactaaagc ctgcccttcg
    28561 ctgaccttat cgcccacaga aacaaggatt tcatctaaat cacccttact agcatcaaaa
    28621 taaacatatt gttcattttt tgctgttact gtccctgaca ataaaacaga ggatgccacg
    28681 cttccttcct tggcaacaac aagatgagta ggctcatctt ttagagcagt ctgagaaggt
    28741 tgtctaaaga gtaaaatccc cccggcaccc aatacaacta cactcgcagc accgattgct
    28801 gcatacagtt gccacttttt agctttacca ttctttttct tcataatgaa actccttttc
    28861 ttttttacaa tactttgcta ttataccaaa tttccctcca gcaaacaatg cagttcagat
    28921 ggaaataatg gcagttcagg attaaacaat cgttcggaat tttacttttc tattgtacta
    28981 gatatataat acactatctt aacttatttg gcaagctttt ttgcaatttt ttgtgcgtag
    29041 cagatttttg caatcaaatc aaaaaaagaa taaaatataa ctatcaaaaa agacgctcta
    29101 ctatttaaaa gattacaaag gagttttcaa tgagagaata tgatatcatt gctatcggtg
    29161 gaggtagcgg aggaatcgct accatgaacc gtgctggtga acatggagcc aaagcagccg
    29221 ttattgagga aaagaaatta ggtggaacct gtgtcaacgt cggttgtgtt cctaaaaaaa
    29281 tcatgtggta cggggcgcaa atcgctgaga ctttccatca atttggagaa gactacggct
    29341 ttaagactac tgatcttaac tttgactttg caaccctacg tcgcaatcgt gaagcttaca
    29401 ttgatcgcgc tcgttcttct tatgatggta gttttaaacg caacggtgta gacttgattg
    29461 aaggtcatgc tgaatttgta gattctcata ctgtaagcgt aaatggtgaa ctgattcgtg
    29521 ctaaacatat cgtgattgct acaggtgccc atccaagtat tcctaatatt cctggtgctg
    29581 agctaggtgg ctcttctgat gatgtatttg cctgggaaga acttccagag tcagttgcca
    29641 ttctaggtgc tggttatatc gccgttgaat tagctggcgt actccacact tttggtgtca
    29701 agacagatct ctttgttcgc cgcgatcgtc ctttacgtgg ttttgattcc tacatcgttg
    29761 aaggtttggt caaggaaatg gaaagaataa acttgccact tcatactcac aaagtccctg
    29821 ccaagttaga aaaaactgct aaaggcatta ccattcattt cgaggatggt accagtcaca
    29881 cagctagcca agttatctgg gctacaggtc gccgtccaaa cgttaagagc ttgcaacttg
    29941 aaaaagctgg agtgactctg aatgaacgtg gctttatcca agtagatgaa taccaaaata
    30001 ctgttgttga gggaatctat gctctaggtg atgtaacagg tgaaaaagaa ctgactccag
    30061 ttgcaatcaa ggccggacgt accctatctg aacgtctctt taacggaaaa actactgcaa
    30121 aaatggatta ctcaactatt ccaactgttg tcttttcaca ccctgctatc ggaactgttg
    30181 gtttgacaga agagcaagct attaaagaat acggtcaaga ccaaatcaag gtttataaat
    30241 caagctttgc atctatgtac tctgcttgca ctcgcaaccg tcaagaatcc cgtttcaaac
    30301 tcataacagc tggttcagaa gaaaaagttg tcggacttca tggaattggc tacggcgttg
    30361 atgaaatgat tcagggattt gccgttgcta tcaaaatggg agcaaccaag gctgactttg
    30421 atgcaactgt ggcaattcac ccaactgcat ctgaagaatt tgtaaccatg cgttaatcga
    30481 aacaaaagaa gctgatataa atatttctgc ttctttttta atgattttcg aatcaacaaa
    30541 aaaattatcc aacttgacta gtcacgaaaa tcggctgtta cagtttttgt taccttgttt
    30601 ttaaaaaatg gttgacatcg actcctatat gagtataata gttactatac attagaaaag
    30661 aggttaacta ttttgaaaaa agctcacgtt tatgctatcc ctgctattgg ggctgctctc
    30721 attgctgctt tggcacaaat cagtcttcca attggacctg ttcccttcac tctgcaaaac
    30781 tttgcaatcg gcttgattgc tactgtcttt agaccgagag aggctgtact ttctgctgga
    30841 ctctatcttc ttctaggtgc tatcggtctt cctgtctttg caggaggtgg agctggtttt
    30901 caggctttag ttggccctac tgcaggctat ctttggtttt atctcgttta ctctggactt
    30961 acttcctctc taaccaacag caagagtggt gttgttaaga tttttcttgc aaacctcttg
    31021 ggtgatgccc ttgtctttgt cggcgggatt ctcagcttgc atttcctagc tggaatggca
    31081 tttgaaaaag ctcttgctgt gggggttctt ccctttatca ttccagacct tggcaaactt
    31141 ctggctatta gttttattag ccgtccccta cttcaacgcc ttaaaaatca ggcttacttt
    31201 actaactaaa aaaggatatc gagttatcat gactcaatat ccttttcttt tattttgaaa
    31261 acttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggc tgctcaaaac
    31321 actgttttga ggttgtggat gaaactgacg aagtcagtaa ccatacatac ggcaaggcaa
    31381 agctgacgcg gtttgaagag attttcgaag agtattagtt gcctttaaag gcatccacca
    31441 tcgtttgaaa ttcttcattt gagagagtaa tccctttgcc cattttagta tggtctggac
    31501 tccaagcacg aatatcaaac tttgcagggg caccattaaa gctcacacgg ttaatttcct
    31561 tggtccaacc tttttcgttt tcagaaagag tcaacaagtg ctcttcgatt tcaaatgtaa
    31621 attctgccat tttcttctcc ttttttagtt tcattagttt attcgtaaaa tcttgtagat
    31681 tttaggaaaa ttttatataa tattgatata aaagaaggga ggccaatatg agacataaat
    31741 tccagcaagt tctaaataaa atacatgatt ttttaaatgg atatgaccaa cctgaccaga
    31801 ctgaaaccaa ctcccttaca gccactattg aagaggctat ccagaaacaa accgctgttc
    31861 accttatctt atctgagaca agctttacag gtgacatcat caaatatgat cagcaaggcc
    31921 agcaaattat cgtgaaaaat ttttccaaaa atgtgagccg gattatccgt ataagcgata
    31981 ttcaacgcct gcgatttgtc ccctcaactg tccaaacagc ccaaaaaaat agatttaaga
    32041 aagagtgaga tgtagttgct tcatcccact ctttttctta gcgaatttgt tcaaaatgta
    32101 aatgaactgc gatatgatct ccataaccac ttctttccaa gtcacgttgt aaacgatagg
    32161 aaatatagtg ttctgcaatg gtaatgtaac ctgcgcccaa taaacgatgt tcaaccatag
    32221 attgaatcat actgatagtc gcacgttcca ccttggcttc ttgtaaatcc aaaactacct
    32281 tcttagtgac ttgagcaaga ttttgacgca aatcatctgt caaaacataa acagtttggg
    32341 ctgccttcaa gatggcttgg taaatcttat ctggattaaa ttcagcaatt tcgccattac
    32401 gtttgattac ttgcataggt ttctccttta ttctttgttt tctttgattt ctgccagcat
    32461 tttttcttct tctactgtca gttgataatg ttcaagtaaa tccggtctgc gctcgtaggt
    32521 tttctttaaa ctctcgtaca atcgccactg acgaatcttt tcatgatggc cactcatcaa
    32581 tacatctggc acgaccatgc ctcgataatc atagggacgt gtgtactgag gatattctaa
    32641 aagacctgaa gaaaaactat catcttggtg gctagactcc ttgccaatca cttctggaat
    32701 caggcgaact gtagcatcaa tcatggtcat agctgccaat tctccaccag tgaggacata
    32761 gtcacctagg gaaatctcat ctgttaccaa ggtcttaatg cgctcatcat aaccctcata
    32821 gtgcccacag ataaagatta gctcttcctc ttgagccaaa tcttcagcat aagcctgatc
    32881 aaactgcttt ccagcaggat caaggagaat aacgcgcgga tttttctttt caatagcatc
    32941 aaaggaatcg aaaataggtt gtgctctgag caacatgccc tgaccgcctc cgtagggctc
    33001 atcatctaca tgacgggcct tttcagcatt ttctcgaaaa ttatgatact ggatatccaa
    33061 gagccctttt tctcgagcct ttccaacgat tgagtgctcc agtggagaaa acatctctgg
    33121 aaagagggtt aaaatatcaa tcttcatcgt ctaacccttc taagatttcc acatcgaccc
    33181 gtttatttgg aatatcaaca ttgagaacca ctggtgggat ataaggtaaa agcaaatcac
    33241 gtttgccttt tcgtttgacc acccagacat cattagcacc tggttgcagg atttccttga
    33301 tggttccaac caagctatca ccctcataga cttccaaacc gataatctcg tgatagtaaa
    33361 attcaccatc gtctaggtca ttcaaatctt cctcagcgac cttgagactg tatcccttgt
    33421 acttttcgat agtattgata tggtacatat ctttgaattt aataatgtca aagttcttct
    33481 gtttacggtg gctagcgatg gtcactgttt ggacaaactg atctttttca tcaaacaaag
    33541 ccagctcagc tcctttttta aaccgttctt ctgcaaaatc cgtcacagac aagactcgca
    33601 tctcaccctg taatccctgc gtattaacga ttttcccaac attaaagtag ttcatcttgt
    33661 ctcctgtaat ctcctttttt ccatcttatt ctgacaattc tcgaataata gccgcaattt
    33721 tttccgattc tgaccattgt aaataatggt gattccctcc taaaatgagt ttagtattgg
    33781 aagtccaata ttctgattct ctgtactctt tttctctata agtctgacaa aaaataaata
    33841 cagggacatg agattctatc gacaaattct caaaatcttc ctcagtaatc tctccagata
    33901 tctgaaattc tggatcttga ttttccaact ctaagccttt ttcttgcatt aattcccaga
    33961 tttttttatt cgtttcagga ctaaatgttg cttgagttaa gttcttaaaa taaagttcag
    34021 gaccacactc gtcaatcagc ctcatctgct cttccatttc tggataagga ttttctgaaa
    34081 aatcagcaaa catgactttt ttagttgtcg gttcaattgc tactaaagtc tgacacttaa
    34141 ttggtttctc gagtaatttg caagctaaaa ttccactcca actatgtaca caaagtatat
    34201 attcagaaat ccctaattct tcaagtgctt cataaaccac atctgcaaga ttatctagat
    34261 tttttccagc ttggtcatga atcggactcc tacctgtgtt cggaaaatca attgtcaaat
    34321 aaccaattgt aggaggaggt ttttcaagta taagtgaaaa attttcataa cttggtagca
    34381 aacctgctcc gtttagacaa actagcactt tcttttgctt ttgataagca acagagagac
    34441 taccaatttc tgtagatact tcaaacctct tcataaagaa atccactgat tctatataat
    34501 gaattattaa aaatccttat cctttatttt atcacgttcc aaggattttc tcaagttgga
    34561 ggaaggggac aatatctcta ctttcccttc aataatcctt ccaaattatg tttatgttgg
    34621 taattaacgg ctgcggtttt gtctttctca aagacagtct tggtaaggtc aatatgatta
    34681 atagctacga ttgcgacggt gtagtaaatg atatcagcca gttctctggc aagttcctcg
    34741 ttcgaatcct atcccttctt ttcgaccaga gcgcctattc aaaacctcgg ctacttctcc
    34801 gacttcctcc actaacttca taaagagacc ttcatcagtc cgagactgct gttaatgttc
    34861 gattaagtag ttttggaatt gcctaaacgt tcaatctttt atagtatatt gaaactagaa
    34921 tagtacacct ttacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttg
    34981 tcctgttctt gtttcatttt actatatctt ctattccaca caaaaaagcg agacatccgt
    35041 cccgcccttc ttatttttcg tcaataacga ttcttacttt tttgtattca gttgggacag
    35101 agtagacaat cgttcttatc gcagaaatag tgcgaccctt acgaccgatt acacgaccca
    35161 catcgctttg atcaagattc aaatgatatt ccaaaaattc tggtgtatcc tcaatcttga
    35221 tagttaaggc atctggttgt gaaattaagg gtttcacaat cgcaataatg agattttcaa
    35281 tcgtatccat ctgtcaacct actttaaact tattttgaaa atttagaatc gtggaatttt
    35341 ttcaatacgc cttcttttga aaggatgtta cgtactgtgt ctgaaggttg agctccatta
    35401 gccaaccatg caagaacgcg gtcttctttc aaagttactt ggttttcagc aacaagtggg
    35461 ttgtaagttc caactgtttc gatgaaacgt ccgtcacgtg gtgaacgtga atctgctacg
    35521 ttgatacggt agaaaggttt tttcttagaa cccatacgag tcaaacggat tttaactgcc
    35581 atttttaaag tctcatttct ttaatttttt atttcggtga aatagctgag ctatttagca
    35641 catgttctat tatagcagat ttctggcatg tgtcaagaaa aaaacttgac agactataaa
    35701 tttcttaaag tatttagaaa tttgttagaa taggaaataa atgtttgaaa gatgctatcc
    35761 gtgaatacta ttttagaaaa attttataaa gaacaccaag tcaaaccctt catatcgcct
    35821 gaacgagagt tggatacttg gcttctaagt cccaagcccg ttcccaagcg aaatatggac
    35881 ttattagtag atgattcact agcaggagat atcattttac tatggagaat ccagtttggt
    35941 acttttacca ctgaaacatg attttaaaaa ctcccattcg aatatgattc aaaattcgct
    36001 tagaatcaat gttttcccac tttttcaaaa aataaatttt catctaattt aaataacttt
    36061 caattaagtg tgaattttgc ttaaaatcat taaaaaacac cccatggtgt gaaccatgaa
    36121 gtgttgtaaa tgctgtgttg tagctagttc ttagcgttta gagaactggc tagctttacg
    36181 agctttctta agatctggtt tccaaaatac tttgagtaca cttatggtat tgatgcccct
    36241 aaacatctaa aaactctggt agaaaaaggg tatgctcttg tcgaaacttc ttttgactca
    36301 cttgaccatc taaataatac catgaaaaag aatatcctga agaagaaggg agttactgga
    36361 ctttctaaaa tgaaatcttg cgacctggat caagcccttc atgagcattt ttcagaagaa
    36421 gaattagctg gtcactttca tgtccttcta tggacttttt tacaatggca ttgctatcac
    36481 acccaatacc tatctaagcg cctggttcgt aaactttatt gcagctcttc ctctaaattt
    36541 cctaattgtt gaaccaattg cccgttttat actaagttct tttcagaaac catttactgg
    36601 ggaagaagtt gaagattttc aagatgatga tgaaatccca actattatct aagccagttc
    36661 tgtaaactac taatatttga aatccacttc cttttagggt acaatggtat aaatgaattt
    36721 ttgagaggat cagaatgaaa aaactagcaa cccttctttt actgtctact gtagccctag
    36781 ctgggtgtag cagcgtccaa cgcagtctgc gtggtgatga ttatgttgat tccagtcttg
    36841 ctgctgaaga aagttccaaa gtagctgccc aatctgccaa ggagttaaac gatgctttaa
    36901 caaacgaaaa cgccaatttc ccacaactat ctaaggaagt tgctgaagat gaagccgaag
    36961 tgattctcca cacaagccaa ggtgatattc gcattaaact cttccctaaa ctcgctcctc
    37021 tagcggttga aaatttcctc actcacgcca aagaaggcta ctataacggt attaccttcc
    37081 accgtgtcat cgatggcttt atggtccaaa ctggagatcc aaaaggggac ggtacaggtg
    37141 gtcagtccat ctggcatgac aaggataaga ctaaagacaa aggaactggt ttcaagaacg
    37201 agattactcc ttatttgtat aacatccgcg gtgctcttgc tatggctaat actggtcaac
    37261 caaacaccaa tggcagccag ttcttcatca accaaaactc tacagatacc tcttctaaac
    37321 tccctacaag caagtatcca cagaaaatta tcgaagccta caaagaaggt ggaaacccta
    37381 gtctagatgg caaacaccca gtctttggtc aagtgattga cggtatggat gttgtggata
    37441 agattgctaa ggccgaaaaa gatgaaaaag acaagccaac tactgctatc acaatcgaca
    37501 gcatcgaagt ggtgaaagac tacgatttta aatcttaaaa accaaaaaaa tacagtatcc
    37561 acattcggta ctgtatttct tttactctca ttcttaagtt aaattattaa aatcccatat
    37621 ttggtctatc cagccttcat aaaagtctgg ctcgtggcag accataagga tagatcccct
    37681 atattctttg agagcgcgtt tgagctcatc ctttgcatcc acatccaaat ggttggtcgg
    37741 ctcgtccagc actaaaacgt tgttttcacg attcatcaag agacagaaac gaaccttggc
    37801 ttgctctccc cctgataata cttgaatctg gctttcaata tgtttggttg tcaaaccaca
    37861 acgggcaagg gctgcacgga cttctgcttg attaagggca ggaaaggcat tccagacagc
    37921 ttcaagagga gtttggcgat taccgccttc tacttcctgc tcaaaataac caagttctaa
    37981 ataatctcca cgctccactt ccccagcgat tggcgagata atgcccaaga gactcttcaa
    38041 gagagttgtt tttccaatac cattagcacc aataatcgca accttttgat tgcgttcgaa
    38101 ggtaagattt aaaggcttag taagaggacg gtcgtaacca atttgcaagt tcttggcttg
    38161 gaagataaag cgccctggtg tacgagctgg tttgaaatca aaggatggtt ttggtttctc
    38221 actttggagt tcgataatat ccatcttatc caatttcttt tgacgagaca tagccatatt
    38281 acgagttgca acacgggctt tattacgagc cacaaagtcc ttgaggtctg caatctcttt
    38341 ctgctggcgt tcgtaggctg cctctagctg agatttcttc atagcataaa cttcttggaa
    38401 ctggtagtag tcaccagagt aacgcgtcag ctgttgattt tccacatgat agacaatatt
    38461 gataacgtca ttgaggaatg gaatatcgtg cgaaatgaga acaaaggcat tctcatagtt
    38521 ttggagatag cgcttgagcc aatcaatatg ctcagcatcc aagtagttgg tcggctcgtc
    38581 caacagcaaa atatcaggct tttcaaggag aagttttgcc aaaagcacct tggttctttg
    38641 cccacctgac aaagaagtta catccgtatc catgccaaag tccataacac caagagcacg
    38701 cgctacttcg tcaatcttag catccaaggt atagaaatca cgactctcca gacggtcttg
    38761 aagttctcct acttcttcca tgagagcatc aacatccgcg ccgtcttcag ccattttcat
    38821 atagaggtca ttgatacgag cttcagcttt gaaaagctca tcaaaagccg tacggagaac
    38881 atcacgcacc gactgtcttt cagcaaggac agagtgctga tccaagtaac cagccgtcac
    38941 atatttggac cactcaacct ttccttcatc tggcagcatt ttaccagtca cgatactcat
    39001 aaaggttgat tttccttcac cattggcacc gaccaggccg atatgttctc ccttgaggag
    39061 acggaaggac acatcttcaa aaattgcacg gtcaccaaaa ccgtgactca gatttttaac
    39121 ttctaaaata ctcattttaa ttccttatct tgtttttatg taatcgttta taaaggagcc
    39181 aagccagata gccacccaaa gtattggtcc acaaatcatc aatctcaaag acgcgattga
    39241 aatcaaagaa aaagtccaag attaattgcg tacactcgat tccaagactc acaagaaaac
    39301 taaaaagaag gacctttttt gttttccgca aatttggaaa tagataaagg agttggaaaa
    39361 tcagaggaaa aaataagaag acattgagga cattttgtaa aaaaatccaa cataattgtc
    39421 caatgtcact cacttcgccc agtttccaga gagaattgaa aggagtcaaa agaaaaacca
    39481 ggcgtccaag atgctgaata cctggagttc ccactcccac ggtagattgt tcttgaggag
    39541 taaagcaaaa atagacaatg caaatgctat agaaaatgac tccccagacc aaaatatgat
    39601 tataagtctt cttcatcatt aaggatttac cgctgcgact gccttctggc ggtcacgttt
    39661 cattgtgtta gagcgcaatt gtccacaagc tgcgtcaata tctgtaccat gctcttgacg
    39721 aaccacacag ttgacccctt ttttcttaag cgtatcatag aaagccaaca cgcgctcttt
    39781 gggactacgg ctatattggt catgctcact aactgggtta taaggaatca agtttacata
    39841 agacaatttc ttgatgttct tgagcaattc agccaattcc aaggcttgtt ctacaccgtc
    39901 gttgacttca ttaagcatga tatattcaaa ggttacacga cggtttgttg tctcaatata
    39961 gtattcaata gcagcaaaga gtttttcaat cggaaaggca cggttaattt tcatgatact
    40021 tgaacgaagt tcattgttgg gtgcgtgaag agacacggca agattgacct gaaccccttc
    40081 atcagcaaag tcacgaattt tatgagccaa acctgaggtt gaaatcatga tgtgacgagc
    40141 accgatagcc attcctttat catcattgat agtacgaaag aaattcaaga cattgttgta
    40201 attatcaaag ggctcaccga ttcccatgac aacgatatgg ctgacgcgtt catcctgacc
    40261 acgctcagca aagtatttct gaaccagcat gatttgcgct acgatttcac cgttattgag
    40321 gtcacgttgc ttcttaatca aaccagaggc acagaaggta caaccgatat tacagccgac
    40381 ctgagtggtc acacagacag ataaaccata gtgttgacgc atgagtacag tctcaattaa
    40441 cataccgtcg ggcaattcaa agagatattt gactgtacca tcagcagact cttgcacaat
    40501 acgttgtttc aagggattga ccacaaactg gtcattgagc ttagcaatca aatccttgga
    40561 aaggttggtc atttcttcaa atgactgcac acgtttacgg tagagccatt cccagatttg
    40621 atctgcacgg aatttctttt ctccctgcta caatacccat tcctgcatgg tttgatgtgc
    40681 caaactatga attgagggtt tcatttcttc tccttattct ctactcactt ctgacgaatg
    40741 acaaaatgac gttgtccctt gtcctctttc tgagaatgct ggtctttctg acgacgtcta
    40801 tttttcttat ctgcattcga ctttcgtttg gtttgagtcg gtttctttcc ttttctagaa
    40861 ggtgtttctt cttccgtctt acgcattttc ttgtcaaatg atgctcgctt aggggcttca
    40921 ttttctaaga caaaataggc acaaccataa ctacaatact ctaaaaggta gtcttgtaaa
    40981 cgactgattt tttcaagttt ttcttctgtt cggtcatcct tgtaaaaacc tcgtaggcga
    41041 agctgttcgt tgctccagtc ccccacgata taatcaaact tggttaagac ttctgaaaaa
    41101 cgctgattaa aagtcgtcac atcaaaggca tccttgatat tttcaaccaa ggaaaaagct
    41161 atcccttccg tttcgacctt atccccgtgt aaatggaact ccggaccagg aaacttgtta
    41221 tagttgtata attcaggtgc aatttctttt cgcatagata tcctttttcc acgattactt
    41281 aatactttat tctaccataa tttctagcag ttagcacgtt tctcataaaa atgaaaaaag
    41341 tctgacgatt ttgtcagacc agaatcttat aacctaaaaa gagaagaaca attcttccct
    41401 ccaactatca ttatttagca gctgcgtaca attcatctac tttattccag ttgattactg
    41461 aaaagaaagc tttgatgtag tcaggacgca cgttgcggta tttcacgtag taagcatgtt
    41521 cccaaacgtc caagcccaag attggttttt taccttctga gattggtgtg tcttggtttg
    41581 ctgttgaagt cacttcaagt ttcccttctt tgttgacaac caaccatgcc caacctgaac
    41641 caaaacgagt tgttgctgct gcagtgaagg ctgcttggaa ttcttcaaat gaaccaaatg
    41701 ttgcatcgat tgctgctgcc agttctgctg aaggagctgt tttctcagga gtcatcaatt
    41761 cccagaaaag agcgtggttc aagtgtccgc caccattgtt gataagtgct tgacggatat
    41821 cagctgggat agattctaca tcagcaagca aggcttcaag gtcttcaccg atttcagggt
    41881 gtttttctaa agctgcattg gcattgttga cataagtttg atggtgtttg tcatggtgca
    41941 aatgcattgt ttccgcatcg atgtatggtt ccaaagcgtc gtatgcatat ggaagttctg
    42001 gtaagataat agccatctgt aatacctctt tttctttcta tatgaaaatg ataacgcaaa
    42061 cattcacttt tttcaagttt tttgcttata gataaggaaa tcactgacat actttctaat
    42121 aaaataagca aatcagcaag aaacccacga caagataatc ctgacgcggg ttgtagtttc
    42181 aacaaatgtc aattgacctg actagcaatc tgtaagagtg ccttttcaaa aaggaaacct
    42241 ttttcataaa gacctgtctt aatctgatag tctgtctcaa tcaaatagga aatagcttgc
    42301 ttcagaaagc tcaaagaaag tcctctcgaa tctcttaatg caaacttgat ttgataagga
    42361 tttgggttac gtcccagata actacctaaa ctacttgcaa tctgcgattc tgtttggcca
    42421 gactccgcca aaatcttcac ctgagtaaaa gtccgaaatt gtcccagcat gactgcaatc
    42481 agtttgattt catcttcccc ttgcaaggtc aagtctctca ccaaatcgcg cgcctgatcc
    42541 atctttttag tcagaataaa ctgagttaaa tcaaaaatat tgtcctgcaa ggtcttggga
    42601 attgcgttaa caatatcctc ttcctcgata acagaatccg ccttatagga ctgtaaaaag
    42661 agaagatttt tctggatttc gctaaattga aaccccgact tgatgaggag attttcaaaa
    42721 gaatgattgg taaactgcag accttgtttc tgactccact tttggaaata ctggcgcaat
    42781 tcttgttctt ttacttctac tgcatcgaag gccttggcat cacgcttaag taatttgact
    42841 aaccgtcttt tgctatccag ctttccttct gcaaagatta tcaacttggt tgttggagaa
    42901 ggattgtcaa ggtattcctc aaatgactta agctcatcat ctgtcaaaaa gcgtttctta
    42961 gcagtcgtga tatccataaa ataatctaat atcacgattt tctcatccgc aaagaaagga
    43021 aggctgacca actccagttc cacatccttg taaactactt ctttcatatc aaagtaggca
    43081 aagttgaggt cagcagaatc atacccaatc tgtttcaaca tttgactctt catcacttca
    43141 aactgaccct gatctgtccc tgtaaatagg ctcaggctcg gtaaatttga taaagtcaac
    43201 ttctgacttt cttcaatggc tagcatcgtc ccttctttct tctgattttt cgatttaatt
    43261 tagtcaatat agcgcaattt cccacggaaa tcttctaagc tctcgtagcc tttttccacc
    43321 atgattgctt tcagttcatt ggtaatgcgg tcaaaagcac tgacgccttc tttgtgaagg
    43381 gtcgttccca cctgcaccat acttgctcca cagaggatgt gttcaaaggc atctcgacca
    43441 gtcagaacgc cacctgttcc gataatttgg atttgaggat ttaaacgttg ataaaaggcg
    43501 tgaacattgg ctagagcagt cggtttgatg tattctccac caattccacc aaaaccattc
    43561 ttaggccgaa taacgacaga ttcgtcttct atatagaggc cgtttccgat agagttaacg
    43621 cagttgacaa acttgagcgg atatttgttg aaaatagctg ccgcttggtc aaagtgaaca
    43681 atatcaaaat aaggtggcaa tttaattcca agaggtttgg tgaagtaagc aaacacttct
    43741 gccaaaatcc ggtctgttgt ctcaaaatca taggcaatct gaggtttacc tggaacattt
    43801 ggacaggaaa gatttagctc agtcagacca cgaaaatcac tctcttggac ttttttcaaa
    43861 atagtatggg tttcctctgg agacatgccg accagagata agaagaaagt tcggttcgac
    43921 tctttttcct gcaaatccaa aagataatcc aaataatagt ctaagccatt atttggcaag
    43981 cccatagagt tgatggaacc aagtggaaca tcttggtagc gtggctcagg attcccctga
    44041 cggaagtcca aggtcgctgt cttagtaaca aaggttcctg ccgctgagtt tttgacctct
    44101 tctaactcct ctatcgtcat acaagccaca cctgctgcat tcatcaagca attgtcaaac
    44161 tcaaaaccag caatttgtgt tttcgttgat accatgattc taatcctcca gatttctttt
    44221 attgctaata ttataccata attttaattc taggtttact agattctgtg gttctatcta
    44281 tttattcgga aaagaaagtc tagtacagaa gtcatgctat ggaaacagct agtgtattag
    44341 aagtttgaac aaggcttggg taacagactt ttgaatgaag tccaagcaac aaggagaaat
    44401 ctcaaccatg agtccattcc atgactctgt tgctctagaa aaccttgcaa tagtcaagtg
    44461 ataacgaata aaactttgga ttgaaatatc cccaagatta tctattacga ggagaaatct
    44521 caacctttat catttttaaa gaaatatagt aaaatgaaac aagaacagga gaaatcgatc
    44581 aggacagtca aatcgatttc taacaatgtt ttagaagttg aggtgtacta ttctagtttc
    44641 aatctactat acatgtaaat ctctactttc gcaaaatgga ttttcagaac agtatcccag
    44701 tatagttaaa aactataaaa aagagaggac gttcccctct taaaatctta ttttactgct
    44761 tctttcaaag catctacctt atccaaacgt tcccatggaa gatcaatatc tgtacgtccc
    44821 atgtgaccgt aagccgatgt ttgacggtaa attggacgct tgaggtccag catttggata
    44881 atccctgcag ggcgaaggtc aaagatttga cgagccgctt tttcaagttg actttcagct
    44941 actgttcctg taccgaaagt atcgatacga acagaaacag gttgcgcaac accgatagca
    45001 taggccaact gcacttctgc cttcttagca aggcctgctg caacgatatt cttggcaata
    45061 tagcgagccg cataagaggc tgaacgatcc accttagtcg catctttacc agagaaggca
    45121 ccaccaccat gacgagagta gccaccataa gtatctacaa taatcttacg accagtcaaa
    45181 cctgagtccc cttgaggacc accgattaca aaacgacctg tcggattgat aaagaatttt
    45241 gtcttatcat caagataaga agatggaata acttctttga tgaccttgtc aatcacatct
    45301 tgatggattt gttcattagt ggcctctgga tcatgctgag tagaaataac gactgtatct
    45361 acacgtaccg gacggtcatt ttcatcgtac tcaactgtaa cttgtgattt tgcatctgga
    45421 cggagatagc taatttctcc agacttacga agttctgcca gacgacgaac caatttatga
    45481 ctgagtgcaa ttggcaatgg catgagctct tctgtttcat ctactgcaaa tccaaacatg
    45541 agcccttggt cacctgctcc aatcaagtcc agtggatctt gatcagcatt tccacgaacc
    45601 tccaaggctt cgttaacacc ttgagcgatg tcaggagatt gttccaccaa agatgggtgt
    45661 actcccaccg tctcagcaga aaatccatat tctgtattgg tataaccaat ctctgcaatg
    45721 gtatcacgaa ccacacggtt aatatccaca taggcatttg tagaaatttc accaaaaacg
    45781 tggacagaac cagtatatac agctgtttca gcagcaacgt gcgcctctgg atcctttgct
    45841 aaaatagcat ccaaaatcgc atctgaaatt tggtctgcaa tcttatccgg atgcccctca
    45901 gatacagatt cagacgtgaa taatttacgc tctgacataa aaatgtcccc ccttaaaaaa
    45961 tattgttata gagttacaaa gtactgatag gaaaactctt cgtaataaat acctaccatc
    46021 ttatcgggac tatataactt tatcattata ccatttttaa tcgcaatttg cagtctttaa
    46081 tgtagtgttt cggtttagat agttcgttct cataaagcaa aaagttggag ctcaatactc
    46141 caacaatttc tattaaaatg tttggcgttt agctttacgc tctgcacgac cgcgagcgcg
    46201 attttcagca cgcttggttt tacggcgctt ttcatcaacc gcccattgaa ttttcttctt
    46261 ataacccggt ttgacttttt tctttttctt tttaaccaaa ccaatcattt cgatatcaag
    46321 tttatcttgt tttttctcac ggttggcacg acgatcacgg tcataggtat cttgaaattc
    46381 cccgtctttg accatcttag gactaaactt gattcccaat ttctccaact cacggatatc
    46441 cgagtcatca cttggctgat aaagggtaat agctgtacct ggtaggccat ttcgtccagt
    46501 acgaccaaca cgatgaacaa aaaaagataa gtcttgcgga atggcatcat tgatgacatg
    46561 gctgacacct tcaatgtcaa tcccacgcgc tgccaaatct gttgcgacaa tatactcaaa
    46621 atccagattt tgcacctgat tcatgattcg cttgcgttca cgaggggcaa tatcgccatg
    46681 gatttttgca accttcaagc cttgagcagt cagatatgaa tgcaattcat cagcacgcgt
    46741 tttagtgtta acaaaaatca ttgccaaata cggctgcatc aactgagtca actggtaaat
    46801 ttgagcattc ttatcatgtc ccttggtcga aatcaaccaa ttatcaatgg tgtcagaaat
    46861 aaccgttttg gtcttaattt tctccataac aggatttgat aagtattttt tcaagaatgg
    46921 ttgcagtttt tgtgggatag tcgctgagaa gaccatgaat tgcaagtctt ttggaagact
    46981 gccagcaatc ttatcaacag tttccaagaa tcccatatcc aaggtcatat ctgcttcatc
    47041 aacaacaaat gtcttggctt tatgaatagc taaatcacca gatttaacca agtcgtagat
    47101 acggcctggt gttccaataa caatatgagg ctgattgctt gccaatttct caatctggcg
    47161 agccttatcc gtaccaccca cataattaac cacacgaact tcgacatctg agtgagctga
    47221 aatctgacgc gctacttggt aaatttgagt agccaactca cgactcggtg cagtaatcac
    47281 tgcttgtaca ctatcgctag cttcatctaa ttgctggaaa atcggtaaca agaaagtatg
    47341 agtcttacct gaacctgttt ttgattctcc tactaggtca cgacctgcca aaacaatagg
    47401 aatcaacttg tcttgcacct ctgttggagt tgtaaatttt aactccttca aggcttctct
    47461 aatatagttt ttaaattgaa atttcgtaaa tgacataaca tcctcgattc tatctacctt
    47521 atcaattata ccatatttta ttccattaca gtagtctcac ttatttaggc tatttccagt
    47581 agcttctcta gtaagaaaag gctggaattt tatagttcca acctcttttc agttattatt
    47641 tccagtttaa tatagcattc aagccatagt gatcactcac ttgtagactc ttgttaccat
    47701 caaatacgac atgtaaattt tccaccgcta actctttggt agtaaagaca taatcgattc
    47761 gaaggggttc agtgttccct ttccagccat caatttcagg cggaacagta tagctaccac
    47821 ttttctcttg agcaacttca aatgcgtctt gtaagcctaa tggactagct aaaatagctt
    47881 ggtaaccttc ctgacctgct gggttgttaa aatctccagc tagtaaaagt ggcttgttca
    47941 attttttcaa gacagcctca aatcgtgccc attcttcttg gaaaccttta tcccaccaag
    48001 agagatgaac actggcaact gctagctcct tgccatcgac tacagtttca gctagggcaa
    48061 cacggcgagt atgatagtct gttggatcat ccacatctga aaccaaaatt tctctggctt
    48121 caataggtgt tttagacaag atagccacac cttcatggta gcggtcatag ccgatatggt
    48181 tataagccca ggtccagtag taatttttcc cttgctctaa caacttttca accaagagtc
    48241 taacataatg gtcttggtga ataggctcag ctgctggcaa agcttgataa aggtcattaa
    48301 cctccacctc tgacgaggtc atctcctgat tgatttcttg gaaacaaatc aaatcatagt
    48361 ccttttcaag aatatcttca agcaaaatct ggaatttttc ctctgcttct ttctccatcc
    48421 aactgtgagt attgagtgtt aaaaatttca ttcttttctc ccaaaataag aggttggaat
    48481 acagcttcca acctcaagta tattacaatt ctactttagc aactgctgtt ttagctgcaa
    48541 gagaacctgt tttttctaat ttaactgatt taattgcatc accatttgtg aagacaacta
    48601 ctgttgaagt ttcacgtcct gctgcacgga tagcatccaa gtcagctgtg acaaggagat
    48661 ctcctgctgt aactttttgt ccttcagcaa catgaactgt aaatggttta ccttcaagac
    48721 ttactgtgtc caaaccaatg tgaaccaata cttcaagacc tgcttccgtc acaataccaa
    48781 aagcatgttt tgttgggaag atgcttgata cagtacctga aactggagat acaatgtttc
    48841 catttgcagg ttctactgca aatccatcac ccatcatttt ttgagcaaat actggatcct
    48901 ttacttgttc caaagcaaca acttgaccgt ctgctactga gtaaacttcc tcagtaagat
    48961 ctttgaagtg aacagtgttt tgttgtgctt cagtcatttg gcttggaaga gtttcaggaa
    49021 tgatttcacc tgaatcaagg atatcttgga tatcagattt caaaatgtca gcttttggac
    49081 cgtagatagc ttgaacccct tgtcctttca tgacaagacc catagctcct tctgctttcc
    49141 attgctctgc atttcctact ttatctgcat ctttaacagt tacacgaaga cgagtcatac
    49201 atgcgtcaac atcaacgatg tttacacgtc caccaagaag gttgataatg tttacagctt
    49261 gagagcctgc tgcaactttc acttcactgc tggtttcttc tgaaccttca gcagtttcgt
    49321 agtttccgtt gcgccctgga gttgcgtagt tgaatttttg aatcatgaag tttgcgataa
    49381 agtacatgat tacagcaaag agaacagtta cccaaacgaa gttaacgata tccataccaa
    49441 taccagcact gattgcaata ggtgtacgag tcaagaactc gattgaaccg aatgagtgca
    49501 tacgtaggtt tacgacgtca gccatagcga aggcagcacc ttgaacaagt gagtaaacaa
    49561 gatacatagg tgttgcgatg aacatgaaca tgtattcgat tggttcagta acccctgtca
    49621 agaatgttgc aagagctgtt gcaatcatca tacctttgta tttatgtttc ttgtcagcat
    49681 caacattacg gtagatagca acaatcacac ccatcaagat accgaatgaa ccgatcattt
    49741 gtccaacttt gaaacgagct ggatgtactg tatctaacaa gtgttgatat tgactagcat
    49801 cagtaccttt aaggtttaca aggtctgtta cccatgcaag ccatagtggg tcttgaccga
    49861 atacttgagt acctttagct gcaccagtta aaatgtcata agtaccacca agagctgtgt
    49921 agttcattgg gatagtcaac atgtggtgaa gaccaaatgg caagagcaaa cgttccaaag
    49981 taccatacaa gaatggtgca agaattggag cagtttcttg tgagttggca atccagatac
    50041 cgaagttatt gatacctgtt tgaactactg gccagaaagc agcaagtaga attgcagcga
    50101 ttgctgaacg aagaataact acaaatggta cgaaacgttt cccgttgaag aatgaaagtg
    50161 catcaggaag tttacggaag ttgtagtatt tgttgtaagc agttgcccct acaaaacctg
    50221 agataatccc tacgaatacc cccatgttca aggctggagc ttcaagaaca ctgataaagt
    50281 aatcagcaac tttgattgaa ccaccaaaga aagtagttac catagcatct ggatttttca
    50341 acatatcgcc tgatacacca aagattgtac cagtgatacg gttaatcaag atgaaggcaa
    50401 gaccagcggc gaaagcacca ccagcacgtt ctttagccca gcttcctcca atggctaggg
    50461 caaacaaaat gtgaaggtta ccgataaccc cccaaccgat ttgctcaaga attccacctg
    50521 tgatgacaag tggtgcaaag gttgggttaa tcatcacgat agacttaccg attgaaatca
    50581 tcaaaccagc agccggcata accgcgataa ctaccatcaa agccttaccg aatttttgcc
    50641 aaaattcgaa agacaagaca tttttgaatg tatctttcat cattcaaatc tcctttattt
    50701 ttatttaggc aaacgtttta cgaaaacgtt tgcactttct atgatttaat tataccactt
    50761 taattttttt tgtaaaggct tttataaaaa aattacactt ttttctaaaa aatttctagt
    50821 gcgccaaatt tcaagttcaa attagccatc aagaagtctt ctctggggga cttctttgga
    50881 agctcttttc ttctgcgcat ctcttttcaa aaactcttgt agcaaaaaag gagattttac
    50941 aatctcctca taaaagcagc tattttacct aaatcttcaa gaatcggcgc atggatattc
    51001 ctgatcccaa tgaaccaatg aaaaccccaa tcacaaatag tagggcaatc atcaacggac
    51061 taaataaatc tggactaatc atggatagat tttgccctac caacgatttg ttgacagatt
    51121 ggtaaacaat ttgataaaca ataaagacca aaacagatgg tgcgatagct cccaataaac
    51181 cgataaaggc tccttctaac aagaacggtc cacggatata actgttttta gctccgacca
    51241 agcgcatgat ttgaatttcg cgactgcggg aaataatggt aatacgaatg gtatttgaaa
    51301 tcaagaaaac tgcgataaaa attaacaaag cagcaatccc tagtccccaa acacggataa
    51361 atgaagctaa cttgaagagt ctttctgtat tggcaccgcc atcttgaacc tcagagacac
    51421 cttcaatttt tttagcatct tcggctatag tttttacatc atttggagtg tttgcctcta
    51481 caatataggc atcatagaga ggattggcat ctccttcaaa gattttccag ttatctccca
    51541 ttatctcggt taatttttca tattgttctt ctttacttga aaaggtaaca cttttaaccg
    51601 tagacatgtt cttcaaagaa tcatatacct tgtggtagtc attatttgta acagtttgac
    51661 cttctttttc aattgtctga ctattatctt ccacatcctt tcggatataa actactacac
    51721 ggacattatt ttcaatatct gtagctagtt tcgctgtatt gaaaataaca gatgcaaata
    51781 ttgccaccaa ggtcaaagta atcatgactg aactgacagc agctactgtc atccaaccat
    51841 ttcgtttcaa actttttaag gcttcaaata aatggcgaaa aaatctacta atcatcgtat
    51901 ccatactctc cttttgattc gtcacgaacg acacggccat tttcaatggc aatgacacgg
    51961 tggcgcaagg tatttacaat ctggctatta tgagtcgcca tcaaaatagt tgttccttgt
    52021 aggttaatcc gttccaagag attcataatt tcccatgaat tatccggatc cagatttcct
    52081 gttggctcat cagctatcaa tactttggga ttatttacaa ttgcacgcgc aatcgcaatc
    52141 cgctgttgct ccccacctga gagttcattt gggaaagaac gaaccttatg cttcaatcca
    52201 accaagtcca aaacttccat cactcgtctt ttgatattac ggcgattttc cccgattact
    52261 tccatagcgt aagcaatatt ttcatagaca gttttctttg gtaacagttt ataatcctgg
    52321 aagacaaccc caacactacg acgtagaagc gggacatctt tctttttgat cttaaccaga
    52381 ttaaaaccag caactgatag acttccttta tcgattttta cttcacgata cagagaacga
    52441 ataaaagttg acttccctgc tcctgaaggt cctacgatgt aagcaaattc ccccggttga
    52501 acgctaaccg aaacaccgcg tagagcagtc gttccgttgt cgtatttttt aacgacatct
    52561 ctcatttcaa taattgacat gtgagttcct ttctatctta gctaattcgc cacttgagat
    52621 aagcatcgat aaaaccatct aggtccccat ccataacctt atctacctga gcaacctcat
    52681 agctagttcg gtgatctttt accatagtat aaggcgtgaa gacataagaa cggatttgac
    52741 ttccccaagt gatctccttt ttctcacctt tgagagaatc tacctccgca gccttcttct
    52801 cttgctccat ttgatagagc ttagcctgca acatcttcat ggcgcgatct ctatttccat
    52861 actgggtacg atccactgtt gattggacaa caattccagt tggaatgtgg gttaaacgta
    52921 cacctgttga aaccttattg acgttttgtc caccggcacc acctgaacgg aaggtatcca
    52981 tcttgatatc atcttcacgg atttccactt caatagtatc atccaattct ggcatcactt
    53041 ctacagatgt gaaagaggta tggcgacgtt tggcagagtc aaatggtgag attcgcacta
    53101 agcgatgaac acccatttct gacttgagga gaccataggc attaggccct tcaaatgata
    53161 aagttaccga cttaatacca gcctcatcac ctgcttggta atccaacact tccactttaa
    53221 agcctttagc attaccataa cgagtataca tacgaagcaa catatcaccc cagtcctgcg
    53281 cctcagtacc accagaacct ggatggattt ccaagatggc attgttgtgg tcataaggtt
    53341 ctgacaagag tagagtcatc tcgtagctgg tcattatctt atcaagttcg gctaactgcg
    53401 ctaccagttc atcatgcact gactcgtctt cagccaaaaa atccaataaa atttcgactt
    53461 catcctgcaa ctcttccatc ttatggaagg tattgtaagt gttttttaat tcattcaatt
    53521 cttgcgacgt tttttgggcc gcaatattat cgttccaaaa atcaggttct gtcatcttgt
    53581 tttccaagat ggcaatctct tcctctagcc cttcgaggtc aaagagaccc cctgaaagaa
    53641 gctaattttt cacgatttgc gtcaattttc tgacgaatta ctgaaatgtc cataaatact
    53701 ccttttttac atcatttcat tatagcatat tttatcattt ctttccatct tttgctctaa
    53761 tccccttttc atgaaaaaag aagcctttgg gcttcccttc ttacaagact tttgctgaag
    53821 tgcgagcgat ttcttccact tgaataccat ttgcttcaaa tttttctttc aaggctggta
    53881 aatcaattga tccatcgatt tgcacttcga taatcacctt accatcctta cgcggaatat
    53941 tgactgtatg ggagatattc aaattttctt ctacaatcaa agaaacaatt tttccaagaa
    54001 caccaacttc atcttctgta acaaagcgta cacgaatccc ttcttcgcca taacctgcaa
    54061 tttcaagaaa ggcttggaaa acgtcacggt cagtaataac tccgtatact tgatggttat
    54121 ctacgacagg gagaatacta atcttatttt tcaacatcag ataagttgca tcttctagac
    54181 tagcatagcc tgagacagtg acaacatcgc gaatcatgac atcttttact tttgtcttat
    54241 tcagaagata attcatctca tagatagaaa gacttgttgc tttagatgga cttgcttgtg
    54301 caatggttcc ctcagtcacc aaaccaacta attgatcatt ttcgataaca ggcagacggt
    54361 gcaaaccttg ctctctcatc aaatctgctg catgagatac tgttgtatct ggactaatat
    54421 aaactacctt gcgggtcata aaatctttaa ctgccatgag acttctcctt ttctattctt
    54481 atccccatta tacaatcttt ttgtaaatct atcaaacgct tacatttctt tttcgaaatt
    54541 cagaaaagta tgaataagct agcaaaaaga gctctgaaat cgagctctgt gaatgaaggt
    54601 aagaaatttt tcattcgatt ttttcaatta ttagaaatta agctttcaat gtagatgcag
    54661 atttgtttgc aatctcaatc taccgactaa aaaggtcccc cggactatat tgatgattac
    54721 ttcgtaatct ccatctgccg actaaaacaa tccactggat tgttttagcc acctagatat
    54781 gcttttctga cttcttctga tgaagcgagt tcttttcctg ttcctgatag gacgattttc
    54841 cctgtttcca gtacatatcc tcggtcagag attgcaagtg ctttattggc attttgttca
    54901 atcaagagga ccgttgttcc ttgcttctga atatcttgaa tgatatcaaa aatttcttgg
    54961 ataaagattg gggcaagtcc cattgatggt tcatctaaaa gaagaagttt tggtgttgac
    55021 atgagggcgc gtcccatggc aagcatttgt tgttcccccc ctgaaagagt ggctgcatct
    55081 tggttcttcc gttcttcaag acgaggaaag cgtgagaaaa ccttcttcaa gttagcttga
    55141 ttttcttcac gatttttctt taagaaagct cccatttcaa gattttccat aacagtcaag
    55201 ccaggaaaga cgtggcgtcc ttctggaact tgtgaaagac cacttgccac gattttctga
    55261 gctggcattt tttggatttc ttgacctaaa aattcaatct ttcctgaact tggtcgaacc
    55321 aaacctgaca aggtgcgaag aatagttgtc ttacctgcac cgttggcacc gataagggaa
    55381 acaacttctc cttcattaac ttcaaagctt acatcacgaa ctgcttggat cataccgtaa
    55441 tgcacagaaa gattttcaac ttttaacata gacattaggc ttcacctcct agataagctt
    55501 cgataacgcg tttattggtc ttaatttcgt ctggagttcc ttgagcgatt aaacggccat
    55561 attcaagtac gtagatacgt tctgttactt ccatgaccag attcatatcg tgttcaatca
    55621 acatgattgt aatcttaaac tcatctttga tacgacgaat taactcagtc aattcggctg
    55681 tttcctgtgg gttcatacct gctgctggtt catctaagaa gagaatttta ggttccgtag
    55741 caagggcacg aacaatttcc aaacgacgtt gttgtccgta ggaaagattt ttagcaagag
    55801 tctctgcatc accatctaaa tcaaagattt tcaacaattc caaagcttta gcctttaatt
    55861 ctttttcact cttgtaaaaa gctggtaagc gtaagaaact agtaaaaaca tgctgtttgt
    55921 gatggtttcc aaaagcaatc aaaacattat ctaaaactgt taaatcttta aagagacgga
    55981 tattttggaa agtacgtcca agtcccaaag aggcaatctt ataaggtgat ttcccattca
    56041 aaaggtgacc atctagggtt actgttccct cgcttggttc ataaacaccg gtcaaaaggt
    56101 tgaaaagggt ggttttccca gctccgtttg gaccgattaa tccaaccagt tccccttcgt
    56161 tcaattcaag agtcacatct ccaacagctg ttagaccacc aaaatgtttg gttaactgtt
    56221 ttacttcaag taatgccatt agttttgttc ctccttctta gattttttaa agaaacgtga
    56281 taggctcagt tcccatgttc caaggagtcc acctggtctg aaaatcatta ccaataccaa
    56341 ggccaaagcg taaataatca tacgcacact agcaacatct tggagaagca tattcaaaat
    56401 tcccagaaca atagccgaaa caatcgcacc tgtaatggaa ccgagtccac caaatacaac
    56461 aataatcaaa acgttgattg agttgatgaa ggtgtaatct ttcggtacaa cagacccgat
    56521 aaatcctgcc tgaagtgacc cagcaatact tgcagtaatg gcaccaaaga caaaagcgat
    56581 gattttaatt ttagtcgtat taaccccaac tgactcagca gcgatttcat cttcacgaac
    56641 agagagggtt gagcgaccaa ttgggctacg caagaagttc aaggttgcaa tggttgtaat
    56701 cacgacaaag aagtaaacca tttgccaagt tgtaaagtta ggaatcccta agatacctgc
    56761 cgcaccattt gtaaggcttc caccattgat gataaagata cggataattt cagaaacacc
    56821 cagagttgct accgcaagat agtccccctt caagcgcaag gttggaatgc cgacaagtaa
    56881 ggcaactgct cctgaaagca aagtccctac aagcatagct ccaaagaagg caccgtaggt
    56941 tggtgattta gaaccaataa tagctgctgc ataggcacca atcgccatga aaccagcatg
    57001 accaagtgaa aattgtcctg aaaaaccaac gattaagttg agaccaacag ccaaaataat
    57061 attaattcca atttgttgta aaatctgtac atagaataga ttaagtactc cgactgaaac
    57121 cagtacacta atcaagctat agccagctaa caaaaggagt aaccatagaa tattaacttt
    57181 taaattttcc ttcatcgttt acaccttctc tttcacattc ttaccaagga taccagctgg
    57241 gcggacaatc aagatcaaca acaagattcc ataaacaatg gcatcacgga aatctgacat
    57301 cccaaaggct gtcgcaaagg tttccaatag accaatcaca aagccaccaa gagccgcacc
    57361 aggaataatt ccgataccac caagtactgc ggcaacgaaa gatttaagac ctggagtaac
    57421 ccccatcaaa ggctcaagag agttataata aagagcaatc agaacaccag ccgcacccgc
    57481 aagagcagaa cccaaagcga aggtaaagct aatcgtacgg tttacattga tccccatcaa
    57541 ttgcgccgcg tcgctatcta ctgatactgc acgcatggct ttccccatct tagtcttttg
    57601 gacaatgact tgtaacaaaa tcatcaaaat caaggaaatg gccaaaatca ttaactgcac
    57661 atttgttaag ctaattggtc ccaaatcata tcgaactgtt tgaatcgctt gagggaaggc
    57721 acgggtattg gcaccaacca gatagaccat tccatactcc aataggaaag aaaccccaat
    57781 agccgtaatc aaaacagcaa tacgagtaga gtggcgcaaa ggtcggtaag caagaaactc
    57841 aatcacgaca ccaagaatag ctgtcgctag catagctaca ataagcgcta caaagaaatt
    57901 catttggaaa gaattgatca agaaataacc gataaaggct cccatcatat aaatatcacc
    57961 atgggcgaag ttgatgagct tgataattcc gtaaaccatg gtatatccta gggctaacag
    58021 cgcgtaaaca ctacctagaa tcaaaccatt tacgagttgt tggagcataa gattcactct
    58081 ttctatttat aatcccgagg ggtttccctc actttttgat aggttcttat actcaatgaa
    58141 aatcaaagag caaactagga aactagccac aggttgctca aagcactgct ttgaggttgt
    58201 agataagact gacgaagtca gtcacatata taatccaagg cgacgttgac gcagtttgaa
    58261 gagattttcg aagagtatta aatatcgaaa cagggagtga gtcaaaggct cattccctat
    58321 ttcaacattt ttctattatg gttttacaac ttctgctgct tcaactttac cattgttcat
    58381 ggtcatcatg taagcagttt tgactgtgtt gtggtctgca tcgaagcttg tttgaccagt
    58441 tacaccttca aaatcttttg ttttagcaag gttatccttg atttcacctg aatttttagc
    58501 accttttgct gcgtttgcta caaggtgaac tgaatcataa gccaaggctg caaatgttga
    58561 aggctcttca ttgtacttag cacggtaagc gtcaaggaag gctttagctt tagctgaaac
    58621 ttctacagta gttgagaagc ctgagataaa gtagatgttt gatgcttttt cagcagttgc
    58681 ttgttgtaca aactcctcac cgttgaatcc atcaccacca acgattggtt tgtcaattcc
    58741 catgccacgc gcttggttta caatcttacc agcctcatta tagtaaccag gaacaacgat
    58801 agcatcaaag tctttccctt tcatttttgt aagggctgct tgaaagtctg tgtcacctgc
    58861 tacgaaagtt tcatctgcaa cgatttcacc cttgtatgac tcgcggaaag atttggcaat
    58921 ccctttagca tagtcactgg cattgtcagt gtaaagaaca actttcttag catttaattt
    58981 ttcagaaaca tagtttgaga taatttttcc ttggaagcta tcttggaaag ttccaataaa
    59041 gaggtaatct tgacctttag tcaatccatc ttgagtcgca cttggtgaga tcaatggaac
    59101 acctgctttt gtagcgttcg ctaccgcagc tgcagtcgca ccagatgtcg caggtcctac
    59161 gactgctgat actttagatt gggttacaag gttagttgta actgaagcag cctcagctgt
    59221 ttcagactta ttatctttat cgactacttc gatttgtttt ccatcgatac cacctgcggc
    59281 attgatttca tcaacagcca attgggcacc tttttgttca gctgttccgt atgcagctaa
    59341 agaacctgat tcttcaaagt taaacccgat tttaattgtc ttttcctcta ctgagttacc
    59401 agcagtgttg actgctccag acttcacttc tccacaggct gcaagaagtg ctacacttgc
    59461 aagcgccaca aacgataggg caaatttttt cttcatcttt ttgtctcctt atttcttaaa
    59521 tagtctgtta agaatatacc gaattatcag aaaattgtca atgttttcct tgaacttttt
    59581 cgatgataac gttttcctat cgataaagat tgcccacaaa gggtgtttcc aactcttgga
    59641 tatgacaaac cctaactttt ttaataaatt tttccttgct caagcgtccg accaattgct
    59701 ccacttcttg agttggaaca tagagttgta agtaacgatg tttcttggaa tgataggtaa
    59761 tatctccata atcctgcagt tttttggcat cacgattata gtaaagatag ataatcaagc
    59821 cagagcgatt gactttttca aacatgataa atcctctttc taagaaatct ctccctatta
    59881 taccaaaaaa agcaaaccca gtcgagtttg ccttctatca tcattagttc aatgaattgt
    59941 tggccataat ttcatcaata aagccatatt caagtgtttc ctgggcgctc atccagttat
    60001 cacgttctgc atctgcatgg actttttcca ttgactgacc tgaattttca gccaagattt
    60061 tttccaaggt attacgagtt ttgagcaagt gttctgcagc gatagccata tcagtttgtt
    60121 gggtaccacc acctgtaccg cccattggtt ggtgaatcat gtattcagca tttggaagca
    60181 tgaaacgttt gccttttgcc ccacttgatg cgatgacagt ccccatagat gcagccattc
    60241 ccataacaat ggtttggaca tctgccttga taaagttcat ggtatctacg attgccaaac
    60301 cagctgaaac agaaccacct ggtgtattga cataaaggta aatatctttc gtactatctt
    60361 gggcatccaa gaaaagcaat tgggcaataa cagagttagc catattgtct tcaaccggac
    60421 ctgtcagcat aatgatgcgg tctttgagaa gacgtgagta aatatcgtaa gaacgttctc
    60481 cacggcttgt ttgttcaata actacaggaa tcattcattt ctccttttga gttttaattt
    60541 tgttggtcaa atgactgaag ataagactat tataatatct tggtcaaaaa aggtcaaatt
    60601 tttgctctgc tttcattaga cagaaacaaa aacccaacct cctttcgtga ctagaaatgc
    60661 ttttccaagt cattcttctt ttcgatctta ttttgtaccg aacaagcggt ctccagcatc
    60721 tccaagacct ggaacgatat aaccgtgttc gttcaaacgt tcatccaagg ctgctgtaaa
    60781 gatttctaca tctggatgag cttcttgaag ggcttttaca ccctctggag cagatacaag
    60841 gcagacaaat ttgatatttg atgcgccacg ttttttaaga gaatcaacag ccaagattgc
    60901 tgagccacct gttgccaaca ttgggtctac tacaaaaatt tgacgttggt caatgtcctc
    60961 aggcaatttc accaagtatt caactggttg aagtgtttct tcatcacggt acataccgat
    61021 gtggccaact ttagcagctg gaaccaagct caagagacca tcaaccatcc cgatacctgc
    61081 acgcaagatt gggacgatgg ccaatttctt acctgccaat tgtttttgaa ctgtttttgt
    61141 aattggtgtt tcgatttcca catcttctag tggaagatca cgaagtactt cataccccat
    61201 caacattgca atctcatcta ctagctcacg aaaagctttt gtagaagtat ctgtacgacg
    61261 caagattgac aatttgtgtt gaatcagtgg gtgattaata acttcaattt ttcccatttt
    61321 tggaattcct tctttcaatt tattcttctt attataccaa aaaacggttt aaaaatcttt
    61381 ctaaaccatt tatttttgat aatttttaca ttagatcagc ctctttaaga gctgtctgta
    61441 ctgtctcaag tggtaaatgg gtcaattctg tccctttttc ttgataaagg tattgggcgt
    61501 agtcgtccat tcggtactgg ttgatataaa ccacgcgctt gcagccgacc tgaagcaatt
    61561 gttttgtaca gttgagacaa ggaaaatggg ttacataggc tgtaaagcct ttgggaacac
    61621 cacgctcagc accttgaagg atagcattga cctcagcgtg aagggtgcga acacagtggc
    61681 cttcaatgac caaacattcg tgatcaatac aatgctcagt ccctgacacc gaaccattgt
    61741 aaccagtgga aataacctta ttatctttta ccagaatcgc gcccacttta gcacgtttac
    61801 aagtggaacg attcgcaatt agtagggctt gggctgcaaa atactcatcc caggccagtc
    61861 ttttttcagt catctctttt ctcctttttc tctatttttt aaaaaatggt aaacctaaat
    61921 ctgcaatctt ttcagctggt accttcatgc catccttgat ccattttaga aggacagaga
    61981 cgatggctga gctccagaag gaatgaagat aagagctgac accttttgat ttcccatggt
    62041 atttttctag aaattcctgc atggcttgga caaagatttt ttccagatgg taatccaagg
    62101 ccaattgaat tactctagct tcctttctgg tctcccggaa aaggtgaacc caaaccaaat
    62161 aaaggtctgt ctttaaatcg taatgatgca gctgttccat aatattgtgg acagttcgtt
    62221 taaagacgct ctctaaaatt tcctctttgg agtcataatt gcgataaaag gccgcacgcg
    62281 aaacacctgc acgtttgacc aattcagaaa tactaatctt ggtcagctcc tttttttcca
    62341 agagttgcaa gagggctgtt tcaatggctt ctctggttaa taaattggat tcttggtttg
    62401 attttctgag attttcaaga gacttttcag agattctacg ttcagacata acattttctt
    62461 tctacttgtc acaacagacg gatgatgctt ttgtttcaag agttttcatg atataattgt
    62521 aaaaaaagac agaacctttg tcaatgtata actgacaaag atggagaatt tctatgactt
    62581 ggaagattat tgctgactct ggttgtgatt atcgtcaact gccaacacca gctattaaca
    62641 caacctttgt aagtgtcccc ttaaccattc aagtagctga tcaggtcttt gttgatgacg
    62701 ccagtctcga tattgaccaa atgatggaaa ccatgtatgc aactgcagaa gcttcaaaat
    62761 cagcttgtcc aagcccagat gactatttgc gagcatttga aggtgccaaa aacattttcc
    62821 tagtaaccat cacaggtacc ctttctggca gtcacaatag tgctcaacta gcaaagaata
    62881 tttatctgga agaccatcct gacactaaga ttcatgtgat tgatagttta tctgctggtg
    62941 gtgaagttga cctactcgta gaaaaattga atgacttgat tgaccagggc ttgtcttttg
    63001 aagaagtggt tgaagctatc accgcctatc aagaaaaaac taagttgctc tttgtcctag
    63061 ccaaagtcga taacttggtg aagaacggcc gtttgagcaa gcttatcggt acggtcgttg
    63121 gccttctcaa cattcgtatg gtcggaaaag ctagtgaaac tgggactctc gaattgctac
    63181 aaaaagcaag gggatcaaag aaatcagttc aagctgccta tgatgaatta gtaaaagctg
    63241 gatatgctgg tggccgtatt gtcatggccc aacgcaataa cgaaaaatgt tgtcaacagc
    63301 tctcagagcg aatccgtgaa accttcccac aagcggatat taaaattcta ccaacctctg
    63361 gtctctgcag tttctatgca gaagagggcg gtttgctgat gggctatgaa attgattaat
    63421 tgcattcttg acaagaggtg accatcatct cttgtttttt tgtggtacaa tagagctatg
    63481 aaacattttg atactattgt catcggtggg ggacctgctg gtatgatggc tacgatttcc
    63541 agtagctttt atggacagaa aaccctcctc atcgaaaaaa atcggaaact tggaaaaaaa
    63601 ttagctggga ctggtggggg acgttgcaat gtgaccaaca atggtagctt agacaacctg
    63661 ctagctggaa ttcctggaaa cggacgcttt ctttacagtg ttttctccca gttcgataat
    63721 catgacatca tcaacttttt tacagaaaat ggtgttaaac ttaaggtcga agaccacgga
    63781 cgcgtctttc cagccagtga caagtctcgg actattatcg aagctttgga aaagaaaatc
    63841 accgaactag gtggtcaagt tgctactcaa atagaaatcg tttctgttaa aaaagtagat
    63901 gaccagtttg tccttaagtc agcggatcaa accttcactt gtgagaaact cattgtcaca
    63961 acaggtggta agtcttatcc ttcgactggt tcgactggtt ttggtcacga gattgctcgc
    64021 cattttaagc ataccatcac cgatcttgag gctgctgaaa gtcctttatt aacagatttt
    64081 ccacataaag ccttacaagg tatttctctg gacgatgtga ccctaagtta tggtaagcat
    64141 gtcatcactc atgatttact ctttacccac tttggtttgt caggtcctgc tgccctacgc
    64201 atgtctagct ttgtcaaagg tggggaggtt ctctcactcg atgttttgcc tcaactttct
    64261 gagaaggact tggttacatt tctagaagaa aatcgggaaa aatccttgaa aaacgcttta
    64321 aaaaccttgt taccagaacg cttggccgaa ttttttgtac aaggatatcc tgaaaaagtc
    64381 aaacaactga ctgaaaagga acgagaacaa cttgtccagt ccattaaaga acttaaaatt
    64441 cctgtaactg gaaaaatgtc ccttgcaaag tcctttgtta ccaagggtgg agtcagtctc
    64501 aaggaaatca atcctaaaac ccttgaaagt aagctggtac ctggcctcca ctttgcaggc
    64561 gaagttatgg atatcaatgc ccacacgggt ggctttaaca tcacttctgc cctctgtacc
    64621 ggctgggtgg cgggaagtct gcattatgat taaagattaa aggttgtgaa gaatgaacag
    64681 aagagaggca gtcgaatttg ttaacatgtg tatgattaaa aacggagata aggtcctggt
    64741 ccaagaccga gttagtcccg actggtctgg cattactttt cctggtggtc atgttgaacg
    64801 tggcgaatcc tttgtcgatg ctgtcattcg tgaagtgaaa gaagaaactg gtctgatcat
    64861 ttccaaaccc caactctgtg gtatcaaaaa ctggtatgac gacaaggatt atcgttatgt
    64921 cgtccttttt tacaagacag aacactttac tggtgaactc cagtcttcag acgaagggaa
    64981 agtttggtgg gaggactttg aaaatctttc tcatctaaaa cttgcaaccg atgatatgtc
    65041 tgatatgctt cgtgtgtttc tagaagaaga tctcagtgaa ttcttttact acaaaaacgg
    65101 tgacgactgg ctttatgatt tgaagtaaaa aataggctag gaaattccta gcctatttat
    65161 tctgcatttg tctgaacgta aaccgcaatg gcatctgacg tgtactgggc tgtttcagaa
    65221 ccaaacttgt caatgttttc cttaaactct gggttgtaga cgtaaccttt accgatatga
    65281 ccgaatacct caatagagca gtcaaatcca taagtgcgaa tggcttgcaa gagcttggct
    65341 gcttgctcct ggttttcggt tgctgttgca ggtaaaccaa cttgaagatt ttgtgccaaa
    65401 gtttgaaaga cttggttaaa ggcggccgta gcctcgtctt cgtgaccttt ttggcgttcg
    65461 agcgcttgtc ccatgacttc ttgaccatat ttctctaccg cttcttggtg gtatttttga
    65521 ttgtcttgat agctaaatcc cgtgaatttt tcctcaatgg tcatttttct ttctcctttt
    65581 tgttcttgaa tagttttttg caaggtggaa atcaaggtat ccagatgttg cctttcgcga
    65641 gttagatagt ccaactgcct agtcaaatgg ggcaataaat ctgtcctttc ttcctttaac
    65701 agctctgcta ttttctctaa agaaaagcct agatatttgt agtaaagaat gacctgaagg
    65761 cgttccaaat cctcttgact gtaggttcga tagccgtttt ccgactttaa ggggaccaag
    65821 agtcctatct tgtcatagtg atgcagggtc ttgacagaga cacctgaaag ctgcgcagct
    65881 tcttttatat ggtacatgat ttcctcctta caatgatagt ataacccctc cccttaggtc
    65941 agagtcaagc gtttttgaga aaatttttta acttttttga gaaaggtgtg aaaacttgaa
    66001 aatgattttc ttgacagacc ttagaaaaca tgataggata gtcaagtcta tcaatcaaac
    66061 agaaagctat ttgacaactc aagtagcttt ttcttatttt gaaaaaggag atcagagttt
    66121 aactatgtca gaaaaatcac aatgggggtc gaaacttggt tttattctag catctgctgg
    66181 ctggccatcg ggcttggttc cgtttggaag tttccctaca tgactgctgc taatggcggt
    66241 ggaggctttt tactaatctt tctcatttcc actattttaa tcggtttccc tctcctgctg
    66301 gctgagtttg cccttggccg tagtgctggc gtttccgata tcaaaacctt tggaaaactg
    66361 ggcaagaata acaagtacaa ctttatcggt tggattggcg cctttgccct ctttatcctc
    66421 ttatcttttt acagtgttat cggaggatgg attctagtct atctaggtat tgagtttggg
    66481 aaattgttcc aacttggtgg aacgggtgat tatgctcagt tatttacttc aatcatttca
    66541 aatccagcca ttgccctagg agctcaagcg gcctttatcc tattgaatat cttcattgta
    66601 tcacgtgggg ttcaaaaagg gattgaaaga gcttcgaaag tcatgatgcc cctgctcttt
    66661 atcgtctttg tttttatcat cggtcgctct ctcagtttgc caaatgccat ggaaggggtt
    66721 ctttacttcc tcaaaccaga cttttcaaaa ctgactagca ctggtctcct ctatgctctg
    66781 ggacaatctt tctttgccct ctcactaggg gttacagtca tgttgaccta tgcttcttac
    66841 ttagacaaga aaaccaatct agtccagtca ggaatctcca tcgtagccat gaatatctcg
    66901 atatccatca tggcaggtct agccattttc caagctcgat cccccttcaa tatccagtct
    66961 gaagggggac ccagcctgct ctttatcgtc ttgcctcaac tctttgacaa gatgcctttt
    67021 ggaaccattt tctacgtcct cttcctcttg ctcttccttt ttgcgacagt cactttttct
    67081 gtcgtgatgc tggaaatcaa tgtagacaat atcaccaacc aggataacag caaacgtgcc
    67141 aaatggagtg ttattttagg aattttgacc tttgtctttg gtattccttc agccctatct
    67201 tacggtgtca tggcggatgt tcacattttt ggtaagacct tctttgacgc tatggacttc
    67261 ttggtttcca atctcctcat gccatttgga gctctctacc tttcactttt tacaggctat
    67321 atctttaaaa aggctcttgc aatggaggaa ctccatctcg atgaaagagc atggaaacaa
    67381 ggactgttcc aagtctggct cttccttctt cgtttcttcg tttcgtcatt ccaatcatca
    67441 tcattgtggt cttcattgcc caatttatgt aatcaaaaag gacttgagta gtgaactcag
    67501 gccctttctt tttatggatg gctaacaatc aattccaaac cttgcccttc cagagtccaa
    67561 gcttcaacat cacttggtag gataaagtgg ctgccttttt gaattggata atttttcccg
    67621 tcaacagtta gctgaccttg accagccaag acactcaata agctgtagtc agctgtcttt
    67681 tcaaagtcaa cttttccagt aatttcccac ttgtaaactg cgaagaaatc attagataca
    67741 aggagagtgg aacgcaaatc atctgcttta acagttacag gacggctatt tgctggctca
    67801 ccaatgttca agacatcgat ggatttttca agatgaagtt cacgcaagtt gcctttgtca
    67861 tccttgcggt caaagtcata gacgcgatag gtggtatcgc tagactgctg ggtttcaagg
    67921 attaagatac ccgccccgat agcgtgcata gtcccgcttg gtacatagaa gaaatctcca
    67981 gccttaacag ggactttggt caacaagtca tcccagttct tgtcctcgat ttgctggcgg
    68041 agttcttctt ttgacttggc attgtgaccg tagataatct ctgaaccttc atccgctgcg
    68101 ataatgtacc agcattctgt ttttccgagt tcgccttcat gctcgagtcc ataagcatcg
    68161 tctgggtgaa cttggacact gagccagtcg ttggcatcga ggatcttggt caaaagtgga
    68221 aatacaggtt ctggacgatt gccaaataat tcacggtgtt ccgcatacaa agtagcaaga
    68281 tctgttccct cgtaacgacc attggcaact ttagagactc catttggatg ggctgagatg
    68341 gcccaatatt ctccgatttt ttcacttggg atgtcgtagc caaactcatc acgtagcttg
    68401 gctccacccc agattttttc ttgcataact gattgtaaaa ataatggttc tgacatgtcg
    68461 atctcctgtc tgatttttct cccctcatta tagcaaaaaa agagttcgaa ttgaactctt
    68521 ttttacatct tataaagcag ggagaagatt ttataaaaat agtaaacaaa tgtgctctac
    68581 ccgatgcttg caccattgct ataaatgaca tccttgtacc aatagaagga cttcttcttg
    68641 ctacgtttga gagctccgtt tcctacatta tctcgatcta catagataaa gccatagcgc
    68701 ttattcattt cccctgtgcc agctgaaacc ggatcgatac agccccaagt cgtataacca
    68761 agcaagtcaa ccccgtcttg gtaaatggca tctcgcatgg ccttgatgtg ggcctctaag
    68821 taagtaatcc gatagtcatc tgctacataa ccattctcat ccggtgtatc catagcaccg
    68881 agtccatttt ctacgataat actaaactaa aatcaaaaaa cattatataa tagtgatatg
    68941 aaatcaacta aagaagaaat ccaaaccatc aaaacacttt taaaagactc tcgtacagct
    69001 aaatattata aacgccttca aatcgttcta tagtaaaatg aaacaagaac aggacaaatc
    69061 gatcaggaca gtcaaatcga tttc
//
LOCUS       DAVLTT010000005        63329 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLTT010000005 DAVLTT010000000
VERSION     DAVLTT010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.005"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            163..3264
                     /locus_tag="VYN15_000326"
     CDS             163..3264
                     /locus_tag="VYN15_000326"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV1451708.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGQSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3346..4353
                     /gene="pfkA"
                     /locus_tag="VYN15_000327"
     CDS             3346..4353
                     /gene="pfkA"
                     /locus_tag="VYN15_000327"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV1451709.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4412..5917
                     /gene="pyk"
                     /locus_tag="VYN15_000328"
     CDS             4412..5917
                     /gene="pyk"
                     /locus_tag="VYN15_000328"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV1451710.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6142..6435)
                     /locus_tag="VYN15_000329"
                     /pseudo
     CDS             complement(6142..6435)
                     /locus_tag="VYN15_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167986.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            complement(6601..6826)
                     /locus_tag="VYN15_000330"
                     /pseudo
     CDS             complement(6601..6826)
                     /locus_tag="VYN15_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7674..8546
                     /locus_tag="VYN15_000331"
     CDS             7674..8546
                     /locus_tag="VYN15_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV1451711.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            8559..8723
                     /locus_tag="VYN15_000332"
     CDS             8559..8723
                     /locus_tag="VYN15_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451712.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPLKNETFIGYVQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(8692..9036)
                     /locus_tag="VYN15_000333"
                     /pseudo
     CDS             complement(8692..9036)
                     /locus_tag="VYN15_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9179..9490
                     /locus_tag="VYN15_000334"
     CDS             9179..9490
                     /locus_tag="VYN15_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451713.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            9494..10210
                     /locus_tag="VYN15_000335"
     CDS             9494..10210
                     /locus_tag="VYN15_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1451714.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10340..11155)
                     /locus_tag="VYN15_000336"
     CDS             complement(10340..11155)
                     /locus_tag="VYN15_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV1451715.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11152..12057)
                     /locus_tag="VYN15_000337"
     CDS             complement(11152..12057)
                     /locus_tag="VYN15_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV1451716.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            12399..12764
                     /locus_tag="VYN15_000338"
     CDS             12399..12764
                     /locus_tag="VYN15_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1451717.1"
                     /translation="MLHQGDKNSLLESLSIVERQTLKDIEVIIVNQSTEEIASISQQM
                     NLSFNIKIIDENSFAELSDMITGDYITFLSSNDSLFDWTFEKMYHAIKLSDSDVVLGH
                     FADLVDGVFYFYPLGGIIG"
     gene            12761..13765
                     /locus_tag="VYN15_000339"
     CDS             12761..13765
                     /locus_tag="VYN15_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HEV1451718.1"
                     /translation="MTENLTNVQVLQKMDDTDHRIRKQYRSLFGKLFNSKLLRKINQF
                     DINNLIWRLYIHSKTATYINFPTYIYKPVIDAKPLKDSYKIILENYENRIKDCAVLEN
                     YDIERAKKQYIQELANFSAWLKNDGEYLDSDIVYHKLIAAEKGIFPFLELDRLDFTII
                     SNNCVGGLIYKQLGFQYRTPFVGLFILPDDYYKLTKHFRYYMEQELVFEEELISPSWT
                     HEVYPLGHLGDIDIHFLHYSSIEEARTKWEKRKKRINWNNLYFKFDNKDSASEEILNK
                     MDNLPYSNKLILVNRPYKNLKSQCVIPGQEHLPELAIMSDPLNTFDIMAWLKKGGNAL
                     "
     gene            13867..15996
                     /locus_tag="VYN15_000340"
     CDS             13867..15996
                     /locus_tag="VYN15_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV1451719.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVNIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            15983..16432
                     /locus_tag="VYN15_000341"
     CDS             15983..16432
                     /locus_tag="VYN15_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV1451720.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            16491..16763
                     /locus_tag="VYN15_000342"
     CDS             16491..16763
                     /locus_tag="VYN15_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1451721.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(17117..17308)
                     /locus_tag="VYN15_000343"
     CDS             complement(17117..17308)
                     /locus_tag="VYN15_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451722.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            17736..18494
                     /locus_tag="VYN15_000344"
     CDS             17736..18494
                     /locus_tag="VYN15_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451723.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            18496..20484
                     /locus_tag="VYN15_000345"
     CDS             18496..20484
                     /locus_tag="VYN15_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1451724.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(20527..21171)
                     /locus_tag="VYN15_000346"
     CDS             complement(20527..21171)
                     /locus_tag="VYN15_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV1451725.1"
                     /translation="MLRAGVLDANNGIISIAGVVIGVASATSNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEATVSREKLLLDQDRELAKKSLYASYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLGQLFSI"
     gene            complement(21197..22192)
                     /locus_tag="VYN15_000347"
     CDS             complement(21197..22192)
                     /locus_tag="VYN15_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1451726.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRN"
     gene            22899..24374
                     /locus_tag="VYN15_000348"
     CDS             22899..24374
                     /locus_tag="VYN15_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV1451727.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSILLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(24340..25056)
                     /locus_tag="VYN15_000349"
     CDS             complement(24340..25056)
                     /locus_tag="VYN15_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEV1451728.1"
                     /translation="MLYVGIDIAKNKHDVTALNVQGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYNPLLIKKFAKSLSLRKTKTDKK
                     DAHGIALKLLSDPNREQFQHNNRQVELKILTRHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASNSRAFCRALKSSPNHQ
                     IEIRNSLDKTIDFSYSLSFS"
     gene            25311..26171
                     /gene="speE"
                     /locus_tag="VYN15_000350"
     CDS             25311..26171
                     /gene="speE"
                     /locus_tag="VYN15_000350"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV1451729.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            26168..27427
                     /locus_tag="VYN15_000351"
     CDS             26168..27427
                     /locus_tag="VYN15_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV1451730.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVITLIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWVYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            27427..28554
                     /gene="nspC"
                     /locus_tag="VYN15_000352"
     CDS             27427..28554
                     /gene="nspC"
                     /locus_tag="VYN15_000352"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV1451731.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            28551..29636
                     /gene="aguA"
                     /locus_tag="VYN15_000353"
     CDS             28551..29636
                     /gene="aguA"
                     /locus_tag="VYN15_000353"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV1451732.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            29646..30521
                     /gene="aguB"
                     /locus_tag="VYN15_000354"
     CDS             29646..30521
                     /gene="aguB"
                     /locus_tag="VYN15_000354"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV1451733.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(30702..31511)
                     /locus_tag="VYN15_000355"
     CDS             complement(30702..31511)
                     /locus_tag="VYN15_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1451734.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGTASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            31782..32003
                     /locus_tag="VYN15_000356"
     CDS             31782..32003
                     /locus_tag="VYN15_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV1451735.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            32057..32728
                     /locus_tag="VYN15_000357"
     CDS             32057..32728
                     /locus_tag="VYN15_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1451736.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKSLYYPILVHILINITAFWNVWLL
                     LFSGS"
     gene            complement(32780..32977)
                     /locus_tag="VYN15_000358"
     CDS             complement(32780..32977)
                     /locus_tag="VYN15_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1451737.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSSQPY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            32970..33878
                     /locus_tag="VYN15_000359"
     CDS             32970..33878
                     /locus_tag="VYN15_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1451738.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKSQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            33875..34336
                     /locus_tag="VYN15_000360"
     CDS             33875..34336
                     /locus_tag="VYN15_000360"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV1451739.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            34326..35213
                     /locus_tag="VYN15_000361"
     CDS             34326..35213
                     /locus_tag="VYN15_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1451740.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            35216..37099
                     /gene="cbpE"
                     /locus_tag="VYN15_000362"
                     /gene_synonym="pce"
     CDS             35216..37099
                     /gene="cbpE"
                     /locus_tag="VYN15_000362"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV1451741.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELSVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            37179..38309
                     /locus_tag="VYN15_000363"
     CDS             37179..38309
                     /locus_tag="VYN15_000363"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV1451742.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            38319..39581
                     /locus_tag="VYN15_000364"
     CDS             38319..39581
                     /locus_tag="VYN15_000364"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV1451743.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            39585..40382
                     /gene="proC"
                     /locus_tag="VYN15_000365"
     CDS             39585..40382
                     /gene="proC"
                     /locus_tag="VYN15_000365"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV1451744.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            40498..41136
                     /locus_tag="VYN15_000366"
     CDS             40498..41136
                     /locus_tag="VYN15_000366"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV1451745.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            41133..42023
                     /locus_tag="VYN15_000367"
     CDS             41133..42023
                     /locus_tag="VYN15_000367"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV1451746.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            42063..42380
                     /gene="yabA"
                     /locus_tag="VYN15_000368"
     CDS             42063..42380
                     /gene="yabA"
                     /locus_tag="VYN15_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV1451747.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            42383..43252
                     /gene="rsmI"
                     /locus_tag="VYN15_000369"
     CDS             42383..43252
                     /gene="rsmI"
                     /locus_tag="VYN15_000369"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV1451748.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            43470..44525
                     /locus_tag="VYN15_000370"
     CDS             43470..44525
                     /locus_tag="VYN15_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV1451749.1"
                     /translation="MKKYNIVDLFSGAGGLSYGFEMAGFNVLLGIDNDEKALETFQKN
                     HQNSEILCGDIANISYEEDIKPIIGEQKIDIIVGGPPCQGMSLSGPRRFDDPRNKLYL
                     SYIRLVREIQPTAFVIENVIGIVSLFKGQIKDTIIEEFSKMGYKVQFKVLLASDYGVP
                     QNRKRVIFVGTRNDGFEYPEALGTIITTEMAISDLPTLENELGEIEMSYVSEPQNDYQ
                     KLMRKRSNVVLNHVAAKHSEKVISTIALVPDGGNYKNLPKELRETRKFNVAWTRFASW
                     KPAPTIDTGHRHHFHYKYNRVPTVRESARLQSFPDDFIFYGSKTQQFRQVGNAVPPLM
                     AQQIANNLLKYLKNNEE"
     gene            44528..45928
                     /locus_tag="VYN15_000371"
     CDS             44528..45928
                     /locus_tag="VYN15_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV1451750.1"
                     /translation="MYQVPEKYYFRLHHPRPRFKNDVENVLVYMATNISYLGILPKKE
                     FSQQLNDIIKQYAGNADKTEKTINNWRTEISSLFGMMIEKEGFVYSGNRAKELTEDQD
                     LIRFFKTFLYNFEYPGGHLKDNEIVKLCQIGVQFKPAQYLLELFTEASQAEEKTIYLT
                     DEEVAHCIFNDLRCTRDREPVLEIWNRIKENRASKVAYDTKGDVIRYAKDILDYMVIA
                     SLLTVQGGRYKINSMEEQAINDFLQSDATFDGYAQFIGNASTTIEDVRNFRSAWFEYV
                     NRDLGDIDFRTNFNLYLPSDIDFTEEKTDIIGHLTEHIEYSEKISTAVVGSSGEAIVI
                     NHEKQKLREHGQEQLLHLVNFIPTQFGVGYDVQSFECDDSELRKYIEVKTTVSNASIT
                     FNSFHITPNEWRTAKSVRDRYYIYRLQISKHSKKLFIIKNLYELVKNEKMLLIERKDG
                     YDVRFSSSVGFEENLI"
     gene            45925..46965
                     /gene="dcm"
                     /locus_tag="VYN15_000372"
     CDS             45925..46965
                     /gene="dcm"
                     /locus_tag="VYN15_000372"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEV1451751.1"
                     /translation="MKKLKIASLFSGGGGTDIGFAGGFDFLGKHYADNQIEIVYANDI
                     EDSANKMFEKNFGVTPDNRNIREIKSDEIPSFDILTGGFPCQSFSVSAQNPKRLGIKD
                     EKGTLFFEMVRVLKAHQPKAFFAENVKGILSANNKEAFPLIIEEFEKAGYNVSYKLCV
                     ATKYGVPQKRERVFIVGIRKDLNFTFEFPEEPIQNVEDYTPLKVILQQDIDEKYYFSE
                     RAVQGMLNSKSGKKMNKGRAQDIEQPSNTVSSHLAKVSLNSTDPVLLENGRYRRYTPR
                     EVARIQSFPENYELLGSEGAQYRMLGNAIPPVMMWYIAEKLVSDLRNSDVIAKQQKLE
                     ESFGQLDLFEAS"
     gene            46990..47784
                     /locus_tag="VYN15_000373"
     CDS             46990..47784
                     /locus_tag="VYN15_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HEV1451752.1"
                     /translation="MELNFQDKSFIKVFFNSDGYVLNFSNSTFANFTFNSVGVNIQEK
                     YGGSKGKALQAFVDNEPDELVLKLALDLLRYYEDLPDSYYEKTEERNSQALKLKERLS
                     KYEVSQIAYLNNAAKSLSDYFDSDYIDKQMGIMNEMISRSPADAIGKAKELLESCFKH
                     ILDHEKIEYSNSNDIATLQKKVFKFLNLDSNENISAKNNQDVKVVLSGLNQIIKGINN
                     LRNDKGDGHGKGANFIELPPRYASVVVGSALTVVSFVWETYQDKQK"
     gene            47802..48365
                     /locus_tag="VYN15_000374"
     CDS             47802..48365
                     /locus_tag="VYN15_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000042158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HEV1451753.1"
                     /translation="MSKNQEKLHFQLKKFIVNVGWTHKIHAVRIDELESYIRWFRIAT
                     IIISGVVSSGLVGILWFDEYWIKLVTVFLSLVTTIIFSITKEFNFEERLALERKSVDE
                     LWNLRVLAEILLSEVVYNGKPSSEIQEFFEELKFRRDATYSQLSNASPKNVSKASKLI
                     KSRKDNDYEEDYRYFIPKELMEIKEEE"
     gene            48365..49687
                     /locus_tag="VYN15_000375"
                     /pseudo
     CDS             48365..49687
                     /locus_tag="VYN15_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398657.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
     gene            50031..51365
                     /gene="trmFO"
                     /locus_tag="VYN15_000376"
     CDS             50031..51365
                     /gene="trmFO"
                     /locus_tag="VYN15_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV1451754.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERAFADLEEFLTV"
     gene            51449..52186
                     /locus_tag="VYN15_000377"
     CDS             51449..52186
                     /locus_tag="VYN15_000377"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV1451755.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            52195..52752
                     /gene="frr"
                     /locus_tag="VYN15_000378"
     CDS             52195..52752
                     /gene="frr"
                     /locus_tag="VYN15_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV1451756.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            52812..53666
                     /gene="cvfB"
                     /locus_tag="VYN15_000379"
     CDS             52812..53666
                     /gene="cvfB"
                     /locus_tag="VYN15_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV1451757.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            53675..53890
                     /locus_tag="VYN15_000380"
     CDS             53675..53890
                     /locus_tag="VYN15_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV1451758.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            53976..54944
                     /locus_tag="VYN15_000381"
     CDS             53976..54944
                     /locus_tag="VYN15_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV1451759.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVSLYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(54922..55101)
                     /locus_tag="VYN15_000382"
     CDS             complement(54922..55101)
                     /locus_tag="VYN15_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451760.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            55137..55637
                     /locus_tag="VYN15_000383"
     CDS             55137..55637
                     /locus_tag="VYN15_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1451761.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            55640..55900
                     /locus_tag="VYN15_000384"
                     /pseudo
     CDS             55640..55900
                     /locus_tag="VYN15_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(56268..57378)
                     /gene="ald"
                     /locus_tag="VYN15_000385"
                     /pseudo
     CDS             complement(56268..57378)
                     /gene="ald"
                     /locus_tag="VYN15_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            57555..58124
                     /locus_tag="VYN15_000386"
     CDS             57555..58124
                     /locus_tag="VYN15_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1451762.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDPVLKKVAIGYI
                     INQTYWNQGLTTETNRAVIELAFEKIGMNKLVALYDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            58192..58842
                     /locus_tag="VYN15_000387"
     CDS             58192..58842
                     /locus_tag="VYN15_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV1451763.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            58826..61066
                     /locus_tag="VYN15_000388"
     CDS             58826..61066
                     /locus_tag="VYN15_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV1451764.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVFLLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLPLVYDLRKNIKGLTVLSLLITGLFFLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            61245..61433
                     /locus_tag="VYN15_000389"
     CDS             61245..61433
                     /locus_tag="VYN15_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451765.1"
                     /translation="MTATKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            61465..62052
                     /locus_tag="VYN15_000390"
     CDS             61465..62052
                     /locus_tag="VYN15_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451766.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            62056..63237
                     /locus_tag="VYN15_000391"
     CDS             62056..63237
                     /locus_tag="VYN15_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451767.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
BASE COUNT        19371 a        11212 c        13886 g        18860 t
ORIGIN      
        1 gctttctatt tttatataca atatagtata aatataaaaa tgatgacgaa aatacaaatg
       61 aatagaaaat aaattagtaa gctgatgaaa tttttctcaa gagaagccat ttataggtga
      121 aaatggtata atatagtgag aaggatagag gagaagtgta aattgatcgc acaactagat
      181 acaaaaacag tctatagttt tatggaaagc gtcatttcga tcgaaaagta tgtgagagca
      241 gctaaagaat acggctacac tcatttggct atgatggata ttgacaatct ttatggcgct
      301 ttcgactttc tagagattac aaaaaaatac ggcattcatc ctttgctagg gcttgaaatg
      361 acagtgtttg tagatgatca ggaagtgaat ttgcgctttt tagctctatc tagtgtgggc
      421 tatcagcagt tgatgaagct ttcgacagcc aagatgcagg gggagaaaac ttggtcagtc
      481 ctgtcccagt acctggagga tatcgcggtc attgtgcctt attttgatag agttgagtcg
      541 ttagaactag gctgtgatta ctatataggg gtttatccag aaacactagc aagcgaattt
      601 catcatccta tcttacctct ttatcgggtc aacgcttttg aaagcaggga tagagaagtt
      661 cttcaagttt taacagcgat taaagaaaat ctaccgctca gagaagttcc cttgcgttcg
      721 agacaagatg tctttatatc agcaagttct ttagagaaac tattccaaga gcgttttccg
      781 caagctttgg acaatttaga aaagcttatt tcaggcattt cttacgactt ggatactagt
      841 ctgaaactgc ctcgttttaa tccagctaga ccagcagtag aggagttgag agagcgtgct
      901 gaactggggc ttgttcagaa ggggttgact agtaaagaat atcaagatag actagaccaa
      961 gaattgtctg ttattcatga tatgggcttt gatgattatt tcttggttgt ttgggatttg
     1021 ttgcgttttg gacaatcgaa tggctattat atgggaatgg gaaggggttc tgcagtaggc
     1081 agtttggttt cttatgcctt agacatcacg gggattgacc cagtagagaa aaatctgatt
     1141 tttgaacgct ttcttaatcg tgaacgctat accatgcctg atattgatat tgatatccca
     1201 gatatttatc gtccagattt tatcagatat gttggtaata aatatggtag taaacatgcg
     1261 gcacaaatcg ttactttttc aacctttgga gccaagcaag ctcttcgaga tgtcttgaaa
     1321 cgctttggtg tgccagagta tgaattatct gcaattacta agaaaatcag ttttcgtgac
     1381 aatcttaagt cggcctatga gggcaatctc cagtttcgtc agcaaatcaa tagtaagtta
     1441 gaataccaaa aagcttttga gattgcttgc aagatagagg gctatccaag gcaaacctct
     1501 gtccatgcgg ctggtgttgt aattagtgac caagatttaa ccaactacat tcctctaaag
     1561 tatggtgatg aaattccact gactcagtat gatgctcatg gagttgaggc tagcggactt
     1621 ttgaagatgg actttctggg actacgaaat ttgacctttg tccagaagat gcaagagttg
     1681 cttgctgaaa cagaaggtat tcatctgaaa attgaagaaa tcgatttaga agacaaagaa
     1741 acgttagctt tatttgcctc tggtaataca aaaggtatct ttcaatttga gcaaccaggt
     1801 gccattcgtc tgcttaagcg tgtgcaacca gtctgttttg aagatgtcgt cgcgactact
     1861 tctctaaatc gaccgggtgc tagtgactat atcaataatt ttgtggcaag aaagcatggg
     1921 caggaagaag tgactgttct ggatccagta ctggaggata ttttggctcc aacctacggc
     1981 ataatgctct atcaggagca ggttatgcag gttgcccagc gacttgccgg atttagtctt
     2041 gggaaagccg atattttgcg tcgggctatg gggaaaaagg atgcctctgc catgcatgag
     2101 atgagggctt cctttattca aggttcatta gaagctggtc atactgtgga aaaagcagag
     2161 caggtctttg atgttatgga gaagtttgca ggttatggtt ttaacaggtc acacgcctat
     2221 gcctactcag ccttggcctt ccagttggct tatttcaaaa cgcattatcc agccattttt
     2281 tatcaggtca tgttaaattc ttccaacagt gattacttaa tagatgcact tgaagcaggt
     2341 tttgaagtag cctctctatc catcaacacc attccctatc acgataaaat tgccaacaag
     2401 gccatctatc taggtttgaa atccattaaa ggagtcagta atgatttagc tctctggatt
     2461 attgaaaata gaccttattc taacattgaa gattttatag ctaaattacc tgagaattat
     2521 ctgaaacttc ctctgctaga acctttggta aaagttggtc ttttcgattc atttgaaaaa
     2581 aatcgtcaaa aagtatttaa taacttagct aatctatttg aatttgtgaa agagttggga
     2641 agtttgtttg gagatgctat ttatagttgg caggaatcgg aagattggac ggaacaagaa
     2701 aaattttata tggaacaaga gcttttaggg ataggtgtca gcaaacatcc actacaagct
     2761 attgcaagta aggctattta cccgattacc ccaatcggaa atttgtcaga aaatagctat
     2821 gctattatct tggttgaagt tcagaaaata aaagtgattc gtaccaaaaa gggtgaaaat
     2881 atggccttct tacaggcaga tgatagtaag aaaaaattgg atgtcactct cttttcagac
     2941 ttatatcgtc aggttggaca ggaaataaaa gagggagcct tctactatgt aaaaggaaaa
     3001 atacaatcac gtgatggccg tctgcaaatg attgcacaag aaataagaga agcagttgct
     3061 gaacgctttt ggatacaggt gaaaaatcat gaatcggatc aagaaatttc acgcatttta
     3121 gaacaattta aaggcccaat cccagtcatc atccggtatg aagaggaaca gaaaaccatc
     3181 gtttctcccc atcattttgt agctaaatcc aatgaattag aggagaaatt gaatgaaatc
     3241 gttatgaaaa cgatttatcg ctaaaaatac ggaaaataga agaattttca acgtaaatgt
     3301 ggtataatca gtaagaatgt taaaagaaaa aggagcataa ccaatatgaa acgtattgct
     3361 gttttgacta gtggtggaga cgcccctggt atgaacgctg ccatccgtgc agttgttcgt
     3421 caagcaattt cagaaggaat ggaagttttt ggtatctatg acggatatgc tggtatggtt
     3481 gccggtgaaa ttcatcccct agatgcagct tcagtagggg acatcatttc tcgtggtggt
     3541 actttccttc actcagctcg ttacccagag ttcgctcaac ttgaagggca acttaaaggg
     3601 attgagcaat tgaaaaaaca cggaattgaa ggtgtagttg ttatcggtgg tgacggatct
     3661 taccacggcg ctatgcgttt gactgaacat ggcttcccag ctattggtct tccaggtaca
     3721 atcgataacg atatcgttgg tactgacttt acaatcggtt ttgacacagc ggttactact
     3781 gccatggacg ctatcgataa gattcgtgat acatcatcaa gtcaccgtcg tacttttgta
     3841 atcgaagtta tgggacgtaa cgctggtgat atcgctcttt gggctggtat tgcaactggt
     3901 gctgatgaaa tcatcatccc tgaagcaggc ttcaagatgg aagatatcgt agcaagcatc
     3961 aaagctggtt atgaatgtgg taaaaaacac aatatcatcg tcttagctga aggtgtgatg
     4021 tcagcggctg aatttggtca aaaacttaaa gaagctggag atacaagcga ccttcgtgta
     4081 acagaacttg gacatattca acgtggtggt tctccaactg cgcgtgaccg tgttttggcg
     4141 tcacgtatgg gtgcacatgc tgttaaactt cttaaagaag gtatcggtgg tgttgcggtt
     4201 ggtattcgta acgaaaaaat ggttgaaaat ccaattcttg gtactgcaga agaaggggca
     4261 ttgtttagcc ttactgcaga aggtaagatt gtggttaaca acccgcacaa agccgatatt
     4321 gagctatcta gcttgaataa gagcttgtca taatttacaa tttagttaat aagaccaaaa
     4381 aggtcatata tataaaggag tcacaaaaat catgaacaaa cgtgtaaaga tcgttgcaac
     4441 tttgggtcct gcggtagaaa tccgtggtgg taaaaaattc ggtgaggatg gatactgggg
     4501 tgaaaaactt gatgttgaag cttcagctaa aaacattgct aaattgattg aagctggtgc
     4561 taacacattc cgattcaact tctcacacgg cgaccaccaa gaacaaggtg agcgtatggc
     4621 aactgttaaa cttgcggaaa aaattgcagg taaaaaagtt ggtttccttc ttgatacaaa
     4681 aggacctgaa atccgtacag aattgttcga aggtgaagct aaagaatatt catacaaaac
     4741 tggtgaaaaa attcgtgttg caactaaaca aggaatcaaa tcaactcgtg aagtgattgc
     4801 gttgaacgtt gctggtgctc ttgatatcta tgatgatgtt gaagttggtc gtcaagtttt
     4861 ggttgacgat ggtaaacttg gtcttcgtgt ggttgctaaa gatgatgcaa ctcgtgaatt
     4921 tgaagttgaa gttgaaaacg atggtatcat cgctaaacaa aaaggtgtga acatccctaa
     4981 cactaaaatt cctttcccag ctcttgctga acgcgataac gacgatatcc gtttcggtct
     5041 tgaacaaggt atcaacttca tcgcaatttc attcgtacgt actgcaaaag atgtgaacga
     5101 agttcgtgca atctgtgaag aaactggaaa cggacatgtt caattgttcg ctaaaatcga
     5161 aaaccaacaa ggtatcgata acttagacga aatcatcgaa gcagctgatg gtattatgat
     5221 tgctcgtggt gatatgggta tcgaagtacc gttcgaaatg gttccagttt atcaaaaaat
     5281 gattatcaag aaagtcaatg ctgcaggtaa agttgttatc actgcaacaa acatgcttga
     5341 aacaatgact gaaaaaccac gtgcaactcg ttcagaagta tcagacgtat tcaacgctgt
     5401 tatcgacgga actgacgcta caatgctgtc aggcgagtct gcaaacggta aatacccact
     5461 cgagtcagta actacaatgg ctacaatcga caagaacgct caagctcttc ttaatgaata
     5521 cggacgtctt gattcagatt catttgagcg taactctaag acagaagtaa tggcttctgc
     5581 tgttaaagat gctactagct caatggatat caaattggtt gtaactctta ctaagacagg
     5641 tcatactgca cgtttgattt ctaaataccg tccaaatgct gatatcttag cattgacatt
     5701 tgacgaattg acagaacgtg gcttgatgtt gaactggggt gttatcccaa tgttgacaga
     5761 tgctccatct tcaactgacg atatgttcga aatcgctgaa cgtaaagcgg tagaagcagg
     5821 tctcgttgag tcaggcgatg atatcgttat cgttgctggt gtgccagtag gagaagctgt
     5881 tcgcacaaac acaatgcgta tccgcacagt acgttaagaa aaatataaaa acctatcata
     5941 tccagcttta gagcttgtgt gataggcttt ttgtatagag ggtaagaaat aggcaaaact
     6001 ttcataatgg attgatactc ttcgaaaatc tcttcaaacc acgtcagcgt cgccttaccg
     6061 tactcaagta cagcttgcgg ctagcttcct agtttgctct ttgattttca ttgagtatga
     6121 aataagatat gcacaaattg attagaaagt caaatgaatt tctacaaatg ttttagcaat
     6181 cgtaatgtac ttgtctagat tcgatctgat atattttcga tttaatgata tggtatttaa
     6241 aacctccaaa gtagcttact ccattctttt acttacgtga gtgtagatgt tatttactgt
     6301 tttagcgttt ttgtgttcca ctctaaccat tatagcattc ttctcagcta gtgtactaag
     6361 gagtgtgtgc ctgaaaatat gggaactaag gggctggttt atcggtttct ctagtttagt
     6421 atttgccttt tgcaaagtga tcttaaatgc ctttctctaa atttacatat cactattgtt
     6481 taacaaaatc taatctatct taggtcactt attctttttt tgaaatgtag aatgaacttt
     6541 ttcaaagttt ttcgaatctt ttaaaatctg tttgttttat atcgccattc tccccctttt
     6601 ttaattctcc ctatatagcc tgacaacttt cccgatggta cgaatatggt tgctttcgtc
     6661 taggtggatg tcggagtatt cgggattgag tttttttgag gtagccttgg cggagtttct
     6721 tgacatagtt agtgccgtct acttggaaga tgccgatggt attatagtca atctgtgggg
     6781 tattcttgat aaataggtag tcgctgtttc ttatctttgg ctccatggac ttgctgacga
     6841 cataagcgat tgggtcgtag tcgtctggga taatggaaac tccatatcta aatcgttgtc
     6901 ctgcatcgag cggctacctg cagagataaa ctacctaaca cgagagtaag tagtctgtct
     6961 gtagtcgtcc agtctgatga tttttacgat acttcgtttt tctgatcata cagttgcctc
     7021 tcggcatagg tcagaacttt accttgtctg ggtggttccc gttggtcgta gatagattgg
     7081 atatcgctag gagaatcctt ttgaactgga ggaaagaggg catcgatcaa gctactgaat
     7141 actttaacta agtcaaatat agtatttttc ttagtagacc taaccctttt ttcataattt
     7201 ctaatggtgt ttttacttat acctatctta gtacccaatt cttattgagt ccaaccatta
     7261 ctagtctata ttgttttata gttgattgag tttggaatag tacgctgtag ctgctaaaac
     7321 atttctagaa attaatttga ctttcctaat agagttgttc atatcttatt tcaatctatt
     7381 atgtttttca cctctaacaa tcgcaatctc ttctttatcc atgaatgaaa tcgctttcta
     7441 tttttgtaag taaagcataa cacgaaatcc acgaaaatga aaacctttgt tgtgttttcg
     7501 taaaaaattt gttgacagag cacgaaacgc ctactataat taaatcaagt ttaaggaaat
     7561 aacaaaaaaa caaatcggag ggaaagacga tgaacacatt aaatgagaaa gtaatcaata
     7621 tctgtaaagc agtagttaaa gaaactttaa tccaagacat ttaggagaaa gaaatgaaga
     7681 aatcaagaaa attagccaca ttaggaatct gttcagcctt gtttttaggc ttggctgctt
     7741 gtcaacaaca acatgctact tctgagggga cgaatcaaag gcaaagcagt tcagcgaaag
     7801 ttccatggaa agcttcatac accaacctaa acaaccaggt aagtacagaa gaggtcaaat
     7861 ctctcttatc agctcacttg gatccaaata gtgttgatgc attttttaat ctcgttaatg
     7921 actataatac cattgtcggc tcaactggct tatcaggaga tttcacttcc tttactcaca
     7981 ccgaatacga tgttgagaaa atcagtcatc tctggaatca aaagaagggc gatttcgttg
     8041 ggaccaactg ccgtatcaat agttattgtc ttttgaaaaa ttcagtcacc attccaaagc
     8101 ttgaaaagaa tgaccaattg cttttcctag ataatgatgc gattgataaa ggaaaggtct
     8161 ttgattcaca agataaggaa gagtttgata ttctattttc gagagttcca actgaggcaa
     8221 ctacagatgt caaggttcac gctgaaaaga tggaaacatt cttctcacaa tttcaattca
     8281 atgaaaaagc tcgaatgctg tctgtagtct tgcacgacaa tttggatggc gagtatctgt
     8341 ttgtaggcca cgttggggtc ttagtacctg ctgatgacgg tttcttattt gtagagaaat
     8401 tgactttcga agagccctac caagcgatta aatttgctag taaggaagat tgctacaagt
     8461 atttgggcac caagtatgcg gattatacag gcgagggact ggctaagcct tttatcatgg
     8521 ataatgataa gtgggttaaa ctttaatagt gttatgatat gacagtaatc ttaggatttt
     8581 tatttctatt tttgatgact tggtgggtta tttcaatcgt taatagccag aaaccactca
     8641 aaaatgaaac atttattggc tatgtccaaa gatacgatat tgatgggaat ggctatcaat
     8701 cattaccgtg tcctcagaac tgagaggagt tcttgaaatc gtaacaccac tttgaacaag
     8761 agttacttca acccattggc tccgccggag taagttgctt tcgtgaacac caaaatcagc
     8821 cgcaatttct tcataagtgc ggtattctca cacatattga agagtggcca taagaaggtc
     8881 ttctaggctt aatttaggtt ttcgtccacc ttttgcgtgt ttaagttgat aagctgtttt
     8941 taatacagct aacatctctt caaaagtggt acgctgaaca ccaacaagac gcttaaatcg
     9001 tgcatcagtt agttgtttac ttgcttcatc attcatagaa ctactatacc atattttgtt
     9061 tcgcaggaag tctaatgcta aaatcttatc agtgagaaga tttcttaaag tttattcttt
     9121 gtagtttcat ctgtattagt acataattta acttagagaa aataggagga ctaatcgaat
     9181 ggaattaaaa gattttacag aaaaagaaca ggaaatgatt aagaaaaggc ttacaatgtc
     9241 taatattagt gacaaagaaa ctactgagaa gattctggcg ctagtaccac aagacttgat
     9301 taagcgaatc ccgttttttg tcagaaaaca tgctacaaca cgtacgatta aacgcatttc
     9361 aattgaatac cctgaactct acgctgtagc tcaaacaagt ggtgagattc cagaaaaaga
     9421 acgcgaagaa ttgcgtcaga ttatcacaac tatctttgaa caaaagatga ataagcatag
     9481 tattaagtag agaatgaaaa aatattttat tagcggtttg ggaagcaatg cctatcatag
     9541 caaggatttt tttcaagaac tagattcgca ggtctatttt ctaaatccat atgaaaagca
     9601 tcttcgagat gaaacagaat tgaaatcatg gtttaaaaat gagattgtag aggaagaatc
     9661 tatctgtctg ataggccatt ctcttggagg agatttagct cgttatttcg catcggaatt
     9721 tgaagaagta aagaaactga ttcttttgga tggtggctat ctagatttag ataagatttt
     9781 acctttggat acagagttag aggaaactaa aaattatatc aaatctcaaa ttgtttcgga
     9841 cttagctctt cttatttcta aagagaagtc cgaagcaaag cattggtcag aaaatatgga
     9901 gaaagctgta agacagtcct atcactggaa tgttgagtat aatagatatg agttggctat
     9961 aaattatgaa aatatagaag cgatactccg cctacggaga aaaatacaag cttttaagag
    10021 agaagtggga gataccttgt ttattagtcc tcgctatcct aatggagcta catggagaga
    10081 ggaagcccta aaagaattgc cagactattt taatactatt tttttagaaa actttggcca
    10141 tgagctttat actcaagcac ctaaagaaat cgctagtcta atgaatgagt ggctcgctta
    10201 ttttctatga gctacttgta ttgctggaaa tggtataaga tgaaaatcta caagtcacta
    10261 attttcatat aacaaaaaaa cgaacaggct ctttttctgt tattcagaag agaacttgtt
    10321 cgtttttatc ttgattttct taaaaagctc tatatacata gggattttct ggtttatcga
    10381 ctttggtaaa gctgtcgatt tccaaggttg gaaggttttg tttgagttct ttatggtagt
    10441 gattgaccag ttttcctttg gctgtaatcc aggtgttgtt ttcatactgc cgggtattgc
    10501 ccttggtcag caatccatag acaccagaat ctgcgataca gtggataatg ccgaatcgga
    10561 acagaaattg actattggca tgactggggt cgttatagac aaagcctgta aactggattg
    10621 tcttgccctc aaattcatct ggatagtcgt agatagcctc catgacttcc atatagtttt
    10681 cattagtgat ctgaatacta tcttgggata agtatttatc cgccgccgtt cgcatttcct
    10741 tttcataggc tgattttgaa aaataagaac tagtatctgg tttcaaatat tggcttgtcg
    10801 tcccttcact tgtctgaata gctagatccg ttccttccga tagggggaaa tgataacctt
    10861 tagcagaaac ggtctgagaa tccaagctaa cagttgggaa agttaagccg atgacaagtg
    10921 gaatagccag aagagaaata ctcgtcatct tggccaatcg gctgttcaga tgactgtggg
    10981 ttttgacttg cttcatccag atatacaatt gaacaattgc caagataaag gaaagcacca
    11041 tggagatata ggccagatag gaatagtgca tgttgatgta ctggtttagt ttgcccgaca
    11101 gatggaggta aatagtcagt tcaaaatagc cagctaaaac taaaaatcga atcataggat
    11161 gactccaatc aagagagaat aggctaaaac gaccagagtc acaatcgtaa tgaagtgact
    11221 aataaatcgt gctttcaagt aatttttcat catgagaata tttttgatat ccagcattgg
    11281 gccaatgacg agaaaggcca gaactggtgc caaaccgaaa ctcgagagta gagaagcacc
    11341 tataaaggca tccgcctcac tacagagcga aagaagaaag gctaaaagca tcaagagcag
    11401 gatagcaaaa agaggagtcg cactgataga ggtcagaatc cgagtcggaa cgtagacctg
    11461 tattatagaa gcaaagaggc agccaaatac caaataacgc cccgtatcaa aaaattcatc
    11521 aatggcctgc acaaagactt gaaaaacttt ttttgcagaa ctcaagtaag aaaaatcatg
    11581 ctcatgacaa gccagacgat tttctttctg aatcggttct tgccagaaaa atcctagaaa
    11641 aattcctagt attacagcca caagaatgga acccagagct cgtaataggg cgacatggaa
    11701 ggagttgcca aaggcagaat aggtcgcaaa aagaacaatg ggattgataa caggtgctgt
    11761 cacaagaaaa ggaacggccg tgtaacttgg aacctttttt tccagaaaac gattgatgat
    11821 ggggacgatt ccacattcac aagaagggaa aagtataccg acaaaggtcc caaaaaagat
    11881 tctcccccaa cgatttcgag ggagaaaatg ataaaccttg tcaggtgtga tataaacttc
    11941 aatcagccct gagacaatgc ttcctatcag aacgaaggga agggcttcaa tgataatgga
    12001 gagaaaaatg gctccagttt gaagtacact agatgggagt tgttgaaaag cagtcatcta
    12061 gtttttcttt tctgctttga cttttttctc tttgtcatca gggaaagtaa cttgtttcaa
    12121 atcagggagt ttagcaaact cttcaaacat cttgtccaag tcgtctcgtt ttgtaaattt
    12181 gacagccata ggtgtacctc gattctaaat tctacctcta ttatactatt attttgcgga
    12241 aaagggaaaa gttaaaattt caaattgagt agctaagaga taatatagct tgatattacc
    12301 tgatatatat cataattgtg ctataattaa ataaaaagaa aatcattatc agaaaattat
    12361 gggaggtagt caaactgact tactcaatta gtgttgtttt gttacatcaa ggagataaaa
    12421 atagtttatt agagtctttg tcaatagtgg agagacaaac attaaaagat atagaagtta
    12481 ttattgtaaa tcaatctaca gaggagatag cttccattag ccaacagatg aatctatcat
    12541 ttaatattaa gattatagat gagaattctt ttgctgagtt gtctgatatg attacaggag
    12601 attatattac gtttctatct tcaaatgatt cattatttga ttggacattt gaaaagatgt
    12661 atcatgcgat aaaattatcc gattctgatg ttgttcttgg tcattttgct gatttggttg
    12721 atggagtatt ttacttttat cctttggggg ggataattgg ttgacagaaa atttaacgaa
    12781 tgttcaagtt ttacaaaaga tggatgatac agatcatcga attagaaaac aatatcgctc
    12841 attatttgga aaattattca atagtaagct tttacgaaaa ataaatcaat ttgatataaa
    12901 caaccttatt tggagacttt atattcactc taaaactgca acctatatta atttcccgac
    12961 atatatctat aaacctgtta tagatgctaa acctctaaaa gactcctaca aaatcatatt
    13021 agaaaattat gaaaatagaa tcaaagattg cgccgtctta gaaaactatg atatagaaag
    13081 agcgaaaaaa caatatattc aagaattggc aaattttagt gcttggttaa aaaatgacgg
    13141 tgaatattta gattctgata ttgtttatca taagttaata gctgcagaga aaggaatttt
    13201 cccttttctt gagcttgata gattagattt tacgattata agtaataatt gtgttggagg
    13261 attaatttat aaacagcttg gttttcaata tagaacacct tttgttggtt tatttattct
    13321 tcctgatgat tattataaac ttacaaagca ttttcgttat tatatggaac aagaacttgt
    13381 tttcgaagag gaacttattt caccgagctg gactcatgaa gtttatcctt tggggcactt
    13441 aggagatata gatattcatt ttctacatta ttctagtatt gaagaagcac gaactaagtg
    13501 ggaaaaaaga aaaaaacgca taaattggaa taatctttat tttaaatttg ataataaaga
    13561 ttcagctagt gaagaaattt taaataagat ggataatctt ccttattcta ataaattaat
    13621 tttagtcaat cgtccatata aaaatttgaa aagtcaatgt gttattccag gtcaggaaca
    13681 tcttccagaa ctggctatta tgtctgatcc attaaatact tttgatatca tggcttggtt
    13741 aaaaaaaggt ggcaatgctc tttaagtgca agttattgcg ctgtagcata taaatctatt
    13801 tcctacatat tttttaaatg ttctacgagt taatttgaaa cgtttagctt gtggtataat
    13861 agatttatgg ataaaaaata tgaaaaaatc tctcaggatt tgggagtgac gttaaagcaa
    13921 attgataccg ttctaagttt gacagctgaa ggggcgacta ttccctttat cgcgcgttat
    13981 cgcaaggaca tgactggtag tctggatgag gtggcgatta aggctattat tgatttggat
    14041 aaaagtctga caaatctcaa tgaccgtaag gaagctgtct tagctaagat tcaagaacaa
    14101 ggtaagttga ccaaggaatt ggaagaagct atcttagttg ccgaaaaatt agcagacgtt
    14161 gaagaactct atcttcctta taaggaaaag cgtcgtacca aggcaaccat tgcccgtgaa
    14221 gctggactct ttcctcttgc tcgcttgatt ttgcagaata tagttgactt agagaaagaa
    14281 gctgaaaagt tcgtctgtga aggatttgcg actggcaagg aagccttgac cggtgcagtt
    14341 gatattttgg tcgaagcctt atcggaagat gtgaccttgc gttctatgac ttatcaggaa
    14401 gtgctgagac actctaaact tacttctcaa gccaaggatg aaagtcttga tgaaaagcag
    14461 gtttttcaga tttattatga tttttcagag acagttggaa ctatgcaagg ctatcgtacc
    14521 ttggctctca atcgtgggga gaaacttggt gtcttgaaga tcggttttga acatgcgacg
    14581 gaccgtattc ttgccttctt tgctactcgt ttcaaggtga aaaatgctta tattgatgaa
    14641 gttgttcagc aatccgttaa gaaaaaggtc ttgcctgcta tcgagcgtcg tattcggaca
    14701 gaattaactg agaaagctga agaaggagct atccaacttt tttctgacaa tctgcgcaat
    14761 ctcctcttgg ttgctccact gaaagggcgc gtggttcttg gatttgaccc agcctttcgt
    14821 acaggtgcca agttagctgt cgtggatgca acaggaaaaa tgctgacaac tcaggttatt
    14881 tatcctgtta aaccagcatc agctcgtcaa atcgaagaag ccaagaaaga tttagcagat
    14941 ttaattggtc aatacggtgt agagattatt gccattggaa atggaacggc cagtcgtgaa
    15001 agtgaagctt ttgtagcgga agttctgaaa gatttccctg aagtcagcta tgttatcgtt
    15061 aatgaaagtg gtgcttctgt ctattctgcc agcgaacttg ctcgtcagga gtttccagac
    15121 ttgaccgttg aaaaacgctc tgccatttct atcgcccgtc gtttgcaaga tcctcttgcg
    15181 gaattggtca aaatcgatcc taagtcaatt ggtgtcggtc aataccaaca cgatgtcagt
    15241 cagaagaaac tatctgagag tctggacttt gttgtcgata cagtggttaa ccaagttggt
    15301 gtcaatgtca atacagctag cccagctctt ctttcacacg tagctggact caacaaaact
    15361 atctctgaaa atattgtcaa ataccgcgag gaagaaggaa aaatcacttc acgcgcccaa
    15421 atcaagaaag ttcctcgtct gggagccaag gcctttgagc aggctgctgg tttccttcgt
    15481 atccctgaaa gtagcaatat ccttgataat acaggagttc acccagagaa ttacactgca
    15541 gttaaggaac tcttcaaacg tttagatatt aaagacctaa acgaagaagc ccaaagcaaa
    15601 ctcaagtccc tttcagtcaa ggaaatggct caagagctag acctcggtcc agaaaccctt
    15661 aaagatatca ttgcagatct tctcaaacca ggtcgagatt tccgtgattc ctttgacgca
    15721 cctgtgcttc gccaagatgt cctagatatc aaagacctag tggtaggtca gaagctagaa
    15781 ggtgttgtgc gtaacgttgt tgacttcggt gccttcgtta atatcgggat tcacgaggac
    15841 ggcttgattc atatttctca tatgagtcgc aagtttatca aacaccctag tcaagtggtg
    15901 tcagttggag atttggtgac cgtttgggtc aagaaaattg atactgaacg tgaaaaagtt
    15961 aatctgtcgc tcctcgctcc aaatgaaact gactgattat gtcaagcagg tttcactaga
    16021 agacttcggg agagctttta tccatcatgt ccagtggaat aggcgtctac gttcgacagg
    16081 tgggcgattt ttccccaaag atgggcatct ggattttaat cccaaggttt atcagaaact
    16141 gggtatggag gtttttagga aaattgtccg acatgaactc tgtcattatc acctttattt
    16201 ccaagggaag ggctatcaac acaaggatcg ggattttaag gaacttttga aagcagtgga
    16261 tggattacgg tttgtaccat ccttgcccaa tagcaactct aaaccactca agctttatcg
    16321 ttgtcaatcc tgccagcaaa ggtatcagcg caagcgtagg attgatacca aacgctatcg
    16381 ctgtggactt tgtcgaggta aattgcttct gataaatcag cctgaggact gatgaaagcc
    16441 gagcctcccc gtgatatact atgtctaacc tagcagaaag aggaaatatc atgaacagta
    16501 aattttataa aatgagacgc aatcgcatga tttcaggagt tctggcaggt ctgtcagaca
    16561 agtggaattt tgatgttacc ctagttcgtt tcttgtttgc tatttttaca gttgcaaact
    16621 ttggacttgg cgtgattatc tatatcatcc tagcttctat catgcctacc aaggaagaaa
    16681 tcgaagcaga aatgtacgga acaggcccac gtaaacgcaa agaagcccaa gccattgacg
    16741 acaatgaagg ctggttttgg tgaggttcta cagaagattt ggaataagca aaaagcttta
    16801 aatcaatagt ctaaactgct tgatttaaag cttttttact tttatactca ataaaaatca
    16861 aagtgcaaac taggaagcca gccacaggct gtaatttagt cggcaatgtg aagttgacat
    16921 agtttgcact ttgatttttg aatagtatta ataatatttc gccagcttca tccacaaact
    16981 atagtggatt ggaactagaa taggacacct ctacttctaa aacattgtta gaaatcgatt
    17041 tgactatcct gatcgatttg tcctgttctt atttcatttt attataaaag cagtaattta
    17101 aactcagttt tttaatctat ttttgctgct gagacaatac atttttggaa aaatggtgga
    17161 tgctgataac aactgataac cagcaaataa cataagcagt gccggtaaat tctgtaccga
    17221 taaagtgtgt gtgttcaact aagagctgac cgatgaatgg agagagcaga tagagaagtc
    17281 cgatgagtat atgttctttg tgtttcatta aagcgcacct tctttcctta taggttgaac
    17341 gacttgcaag tgttaaattg aatggtatgt tatctaggta accttactaa aatgttagtt
    17401 cccgcttcct ccttttcaaa gtaagccttt tcacacttat attttacaac tttaaaaata
    17461 ggaaatcaaa tcattttcta agtaattttg cttatatttc acccaatctt acaaaaatgt
    17521 aagattaaag tctcttttgt aaggttaggt tatggcaagc ggtctttttt tgatgtaaac
    17581 tagactcata aagaacaaag gagtaacatc atgaaacaaa tcttacataa gaaaactaga
    17641 aaaccaagtc acaaagaaat tgagcgcgtt cagctgggat gcactatgat gcaagctaca
    17701 tttcatttga tgggatatta agaaaggaga ttctcatgac acttttagat gtaaaacacg
    17761 ttcaaaaaat ttataaaaca cgttttcagg gcaaccaagt agaagccctc aaggatattc
    17821 actttaccgt cgaaaagggt gactacgttg ccatcatggg tgagtctggt tctggtaaat
    17881 caactcttct caatattcta gctatgctgg ataaaccaag tcgtggtcag gtttacttga
    17941 atggaactga caccgcaacc attaaaaatt cacaggcctc tagcttccgt cgtgaaaagt
    18001 tgggctttgt cttccaagac tttaacttgc tagatactct atctgtaaag gacaatatct
    18061 tgcttccgct tgtcttgtca agaagaccta ttacagagat gatgaagaaa ttggtggtga
    18121 cagctgagaa tctgggaata aaccaattac aagagaagta cccttacgag atttctggtg
    18181 gtcagaaaca gcgtgtagca gtagcccgcg ccatcatcac agaacctgaa attctccttg
    18241 cggacgaacc gacaggagct cttgactcca agtcatctgc agccttactt gatgtctttg
    18301 atgaaatcaa tgagcgcggc caaaccattc tcatggtaac ccactcaaca gcagcagcta
    18361 gcagagctaa acgtgtactc tttatcaaag acggcattct ttacaatcaa atctaccgtg
    18421 gagagaagac agaacgtcag atgttccaag aaatctctga taccttgact gtcatggcaa
    18481 gcgaggtgaa ttagtatgtt tcgattaacc aataagttag cggtatcgaa cttgattaaa
    18541 aaccgcaaac tctactatcc ttttgcgctg gctgttctct tggcagtcac tgtcacctat
    18601 ctcttttact ctctaacctt caatcctaag attgcggaaa tccgtggagg aacaaccatt
    18661 caggctacac ttggatttgg tatgtttgtc gtcacccttg cgtcagccat tatcgttctc
    18721 tatgccaata gttttgtcat gaagaaccgt tccaaggaac taggaattta tggcatgttg
    18781 ggcttggaga agcgtcatct tatcagtatg acctttaagg agttagtggt atttgggatt
    18841 ctaactgttg gagcgggtat cggtattgga gccttgtttg acaagttaat tttcgctttc
    18901 ctgctcaaac taatgaaatt gaaggttgag ctggttgcta ccttccagac gaaagttgtc
    18961 attacagtgc ttgttgtctt cggtttgatt ttcctaggcc tcatgttcct gaatgccctt
    19021 cgaatcgccc gtatgaatgc cctccagctc tctcgtgaga aagctagtgg agagaaaaaa
    19081 ggtcgcttcc ttcctctcca aaccattctt ggttccataa gtttaggaat tggctattat
    19141 cttgccctta cggtaaaaga tcctcttaca gccttaacaa ccttcttcat agctgtttta
    19201 ctggttatct ttgggactta tctcttgttt aatgcaggga ttaccgtttt cctccaaatc
    19261 ttaaagaaaa ataagaaata ctattaccaa ccaaataacc tcatatctgt ttctaacttg
    19321 attttccgta tgaagaaaaa tgcagttgga ctagccacca tcgctatctt gtcaacaatg
    19381 gttttggtaa ccatgtcagc agcgacaagc attttcaatt cctcagaaag ctttaaaaaa
    19441 gttctaaatc ctcatgattt tggggtttca gggcaaaatg ttgaaaaaga agacttggac
    19501 aaactcttga gccagtttgc aagtgacaaa ggttataaga ttaaagaaaa agaagtattt
    19561 cgttacactt actttgctgt tgcgaatcaa gaaggaacca agttaactat ttttgaaaaa
    19621 ggacaaaacc gtgtccaacc aaaaacagtt ttcatggtat ttgaccaaaa agattatgaa
    19681 aatatgactg gtcaaaaact gtctctatca ggaaatgagg tcggactctt tgcaaagaat
    19741 gagggagtta aagaacagaa agctctaact ctaaatgatc atcaattttc tgtaaaagaa
    19801 gaatttacta aagattttat tgtcaaccat gttccaaatc agtttaatat tttgactgct
    19861 gattacaatt accttgttgt acctgattta caagcctttt tggatcaatt cccagattcg
    19921 gctatctata atcagtttta cggtggtatg aatgtaaatg ccagtgaagc agaacaactc
    19981 aaggtcgctg aggagtatga aaaatactta caaaagttta atgctcaatt aaacactgaa
    20041 ggtaactatg tgtatggtag cactctagca gatgctagtg ctcagatgag tgccctcttt
    20101 ggtggtgtct tctttatcgg tattttctta tccattatct ttatggtcgg aaccgttctg
    20161 gtcatctact acaaacaaat ttctgaagga tatgaagacc gtgagcgctt tattatcttg
    20221 cagaaagtcg gtttagatca aaagcaaatc aagcaaacca tcaacaaaca ggttttaact
    20281 gtattcttcc ttcctttgct ctttgccttc ctacatctag cctttgccta ccatatgctt
    20341 agtctgattt taaaagtgat tggtgtactg gatacgacta tgatgttgat tgtgaccttg
    20401 tctatctgcg ctatcttcct catcgcctat gtgctgattt tcatgattac ttcaagaagt
    20461 tatcgtaaga ttgtccaaat gtaaaaaaag atacctcgac ttcaaaatcg aggtatttct
    20521 tgttttctaa atgctgaaaa gttgtccgag caggaaggta actcccatag ttaagagacc
    20581 aatagcaagg ttccgaatca tagctgtttt ggttggggct tttccaagtc tagcacttgt
    20641 gtagccagtg agaagaaggg ctacaccgac gataaggacg gtagcaggga tgcggtaatc
    20701 acttggaaaa atggtcactg acagcattgg aggcaaactt ctaaggaaaa aggcaacgaa
    20761 gctagaaatg gcagcgtgcc aaggattggt aaattcttca tactcaatcc catatttttc
    20821 ctctaccaga gccttgagtg gatttttaag aaagatctta ttagtcaaga gttgggcaga
    20881 agttttgaat tctccatttt ggatataaga agcatagagg gattttttgg ctagttccct
    20941 atcttggtct agcaagagtt tttctcgcga aacggtagct tcctcggtat cttttggagt
    21001 tgaaacggat acatattctc caccagccat tgaaaaggca ccagctaaga tagccgcaaa
    21061 acctgataaa aagataatcc agatattgct cgtggcactg gcaactccga taaccacacc
    21121 agcaatggaa ataattccat tgttagcatc aagaacaccc gcacgcagga tatttaaacg
    21181 acctgcaaaa tttgaatcaa tttcgtgatt tgtttctgac gctaaatttc aagttcaagt
    21241 tagccatcca gaagtcttct ctgggtgact tgtagtccaa gcatttttta ggatagttgt
    21301 taatccactt ttcgatgaat gcgacttctt tgggagtcat tttcttggtt cccttaggta
    21361 accatctacg aatgagcctg ttgtgattct cattagttcc cctttcccaa gaggcatagg
    21421 ggtgcgcata atagatgtgc tcctcagaaa atacatcaaa caagcgattg aattccgttc
    21481 cattatctgc cgtgatggaa agaatcttgt gttgttttaa gatgagtttt agagcctgat
    21541 tgaccacatc agcactttta tttggaatca atcggatgat ctgatgtcta ctctttcgat
    21601 ccgtcaagac aagcaagcag tagtttttcg ctctcgtaag tagaaccgta tcaatctcat
    21661 aatgcccatt ctccaagcga agattgatag cttcagaccg ctgttcgatg gattgaccag
    21721 caggtttaaa gttggtgcta gcctgtttct taagcgcttt tccttttcta gggtaaagca
    21781 gatcctgttt gcttaacccc aattttccat gatgaatcca atagtaaatg gttgaaattc
    21841 ccacgttaac ccctttagcc atcaccatca tttcaggcga aaatttttgg ttatgatagt
    21901 ggagaatctt ttcctttagt tccttggtca cgcttgattt cctgaccgag cgcttgcgat
    21961 tgttttcata agactgttga gcatagtcgg cagaataaac ctctttgaag cgcccttttc
    22021 caagacattg tcggactgtc ccacgcttga tttcagtgtg gatagtttga ggagcttttc
    22081 caagcagaga ggcaatttct ctatttgatt tcccttcttt tttccatctt tcgattaagc
    22141 gacggctatc gattgtcaaa tgtttggctt ttgtagtata attgtcttgc atctctgtgc
    22201 ctttcttgtg tttgtggttg aacaacaagt ataacacaga ggtgttttct tatgcctaca
    22261 agagctatca gctagttgaa ccatctaatt tttaggaggg ctgggtggct aacttcatta
    22321 tagaactttc atttacgaac atatagtaaa atgaaacaag aacagaacaa atcgatcagg
    22381 acagtaaaat cgaattctaa caatgtttta gaagtagagg tgtactattc tagtttcaat
    22441 ctactatatt tttgtttttt atcaaaaaat actttacaag ttcttaaaaa catgatatag
    22501 taataaagct tagaaaatga gatgatgttt tctagcaaat ataaacccga gtaaaaaatg
    22561 cctacggaca ggtagggttg aatgccgaag cgtggttgaa aagccacatt attgataggg
    22621 ttaaaagcct acttttataa gttgatgtta ggacacttgt cctaattcat aaatttttag
    22681 tgtggtgaaa gcacacgtca tcttgtgaaa cgatcaataa agtacgtaat atttgctact
    22741 agagagttag gaaacatcgg gaacagacat actcaacaga aaccaaaata aacacgtcag
    22801 aagattgcag agcaggtgaa aacctgctct tttttcatga gtcaaccttt agttccttag
    22861 ttttcataag gtcctaaaaa tattgaaagg agtatgtttt gaaagagtta gatcaaaacc
    22921 aagccccaat ttatgaggcc ttggtgaagt tacgcaagaa aaggattgtt ccctttgatg
    22981 ttccaggtca caagcgtgga cggggaaatc cagaacttgt cgaactctta ggagaaaaat
    23041 gtgtaggcat tgatgtcaat tcgatgaaac ccttggataa tttaggccat cctatttcga
    23101 ttattcgtga tgcagaggag ctggctgcag atgcttttgg agctagccat gcctttctaa
    23161 tgattggtgg aacaacttca tcggtgcaga ctatgattct ggcaacctgc aaggcaggag
    23221 ataagattat tctgccacga aatgtccata aatctgctat caatgcgttg gttctatgtg
    23281 gtgccattcc catctatatc gagatgagtg tagatcctaa gattggtatc gctttaggtc
    23341 ttgaaaatga ccgagtagca caggccataa aggaccatcc agatgctaag gctatcctaa
    23401 tcaacaatcc tacttactac ggcatctgtt cagacctaaa ggggttgaca gaaatggctc
    23461 atgaagctgg catgatggtt ttagtagatg aagcccacgg agcgcatttg catttcactg
    23521 ataaacttcc aatttctgct atggatgcag gggctgatat ggcagcagtt tccatgcata
    23581 agtctggtgg gagtttgacc caaagctcca ttttacttat cggggagcag atgaattctg
    23641 aatacgttcg tcagataatt aacctgaccc agtctacatc tgcctcttac ttgttgatgg
    23701 ctagtttgga tatttcacgt cgcaacttgg cccttcgtgg taaagagtcg tttgagaaag
    23761 tcattgagct atctgagtat gcccgccgtg aaatcaatgc tatcggtggc tactatgcct
    23821 actcaaaaga gttaatagac ggtgtttcgg tttgcgattt tgacgtaact aagttgtcag
    23881 tttacactca gggtattggc ttaacaggta tcgaggttta tgacctcttg cgagacgaat
    23941 acgacattca gatcgagttt ggtgatatcg gcaatatctt ggcctatatt tccatcggcg
    24001 accgcatcca agacatcgag cgcttggttg gtgctctggc tgatattaag agactctatt
    24061 caagagatgg aaaagatttg atagcaggag aatatattca gcccgagtta gtgctgtctc
    24121 cgcaagaagc cttctattca gaaagaaaaa gtttaacttt ggatgattct gttggacagg
    24181 tctgtggaga atttgttatg tgttaccctc caggtattcc tatcttggct cctggtgaac
    24241 gcattacacg agaaattgtc gactatatcc aattcgccaa ggaacgtggt tgctccctcc
    24301 aagggacgga agatccagag gtcaatcata tcaacgttat taagagaaag acaaactata
    24361 agaaaagtca atagttttat ctaaactatt tcttatttca atttgatgat ttggcgatga
    24421 ttttagagca cggcaaaaag cccttgaatt agaagcggtc aatcgcttaa tttctatcag
    24481 cttatcaaat cctgcctcaa tccttttctg aggattaggg tagcgtgtca agagttggta
    24541 ggtatattct gaatgctttc caacgatttt atccaactca ggaaagatga tatcaagaca
    24601 acgagtgtat tgtactttcc aatcagactg ttttttcttg agacgatgaa tatgtctagt
    24661 cagtattttt agttctactt gccgattatt gtgttgaaat tgttcacgat tggggtcaga
    24721 aagaagttta agagcgatgc catgagcgtc tttcttatcc gttttagtct tgcgaagtga
    24781 taatgatttg gcaaatttct tgatgagcaa aggattgtag gtgtaaactt tatatccttg
    24841 ttcatgcagg aagttcagta gattaaaggc ataatgtcca gtatcttcaa gagcgatgag
    24901 acagtcttgg ttgagctgtc gaagagacag atctaagagt tcaaaaccag ctttattatt
    24961 tgaaaaagtg agtggtttaa gaacagtttt tccttgaaca ttcaaggctg taacatcgtg
    25021 tttattttta gcgatatcaa tgcccacata aagcatggga gtacctccag atgtagtatt
    25081 tcaagtctac ttggttatcc acgaactttt tgccttgtta ccttagacga gataaaacgt
    25141 ctatgcgtta tcaaactcat taccaattga aacaaaagct gtggttagag cctttcggaa
    25201 atcgtcaagc gattggagga aatgaactaa tccacagtgg cttattccaa gtataccact
    25261 tgggctttgg cagtagctaa ctgcgctaaa tataatataa ggagaaatag atggatttat
    25321 ggttttctga agttcatact ccagatgtca aattgtctct gagaacagcc aagcaacttt
    25381 acgctggaaa aagtgaatgg caggatatcg aagtcttgga tacgccagct tttgggaaaa
    25441 tactgatttt aaatggccat gtcttgttct cagatgcgga tgatttcgtc tacaatgaaa
    25501 tgaccgttca cgttcccatg gctgtccacc caaatccaaa gaaagtattg gttattgggg
    25561 ggggtgacgg cggtgttgcc caagtattaa cactctatcc tgaactggaa caaatcgata
    25621 tcgtggaacc ggatgagatg ttggtcgagg tctgtcgtga gtatttccca gactttgctg
    25681 cagggctaga tgatcctcgt gttaccattt actaccaaaa tgggctacgc tttttgcgaa
    25741 actgcgaaga tgattacgat attatcatca acgatgcgac agatccattt ggccatacgg
    25801 aaggactctt taccaaggaa ttctacggca atagttatcg agctctgaag gaagacggca
    25861 tcatgattta ccagcatggg agtcccttct ttgacgagga tgagtcggcc tgccgaagca
    25921 tgcaccgcaa ggtcaatcaa tcctttccaa tcagtcgggt ttatcaggcc catattccaa
    25981 ctagcccagc tggctattgg ttgtttggat ttgcatcgaa aaaataccac cctgtcaaag
    26041 attttgacaa ggaaggttgg aaaaaacgcc agcttttcac agaatactac actgcaaact
    26101 tacacgtggg agcctttatg ttgcccaagt atgttgagga cattttagaa gaagaggaag
    26161 gaaaaaaatg agtcgtttac tagttattgg ttgtgggggc gttgcccaag ttgctatttc
    26221 aaaaatttgt caagatagcg aaacatttac agagattatg attgctagcc gtaccaagtc
    26281 aaaatgcgat gacttgaaag cgaagctaga aggcaaaaca agtactaaaa ttgaaactgc
    26341 agcacttgat gctgacaagg tagaagaggt cattaccttg attgaaagct acaaaccaga
    26401 agctgttttg aatgtagctc tgccttatca agatttaacc attatggatg cttgtttggc
    26461 aacaggtgtt cactatatcg atacagccaa ctacgaagca gaagacacag aagaccctga
    26521 gtggcgtgct atttacgaaa aacgttgtaa ggaacttggt tttacagcct actttgacta
    26581 ctcatggcag tgggtttatc aagagaaatt caaagaagca ggcttgactg ctcttcttgg
    26641 ttctggtttt gacccaggtg taactagtgt cttttcagct tatgccctca aacactattt
    26701 tgatgaaatc cattatatcg acattttaga ctgtaatggc ggtgaccacg gttatccatt
    26761 tgcaaccaac tttaatccag aaattaatct ccgtgaggtt tctgcgccag gttcttactg
    26821 ggaagatggg aaatgggtcg aagtcgaagc tatgtctatc aagcgtgagt atgatttccc
    26881 tcaagttgga caaaaagata tgtatctcct tcaccatgaa gaaatcgaat cattggccaa
    26941 gaacattcca ggtgtcaaac gcattcgttt ctttatgact tttggtcaat cttacttgac
    27001 gcacatgaaa tgtcttgaaa atgttggact ccttcgtacg gataccatta actttaacgg
    27061 ccaagaaatt gttccaattc aatttttgaa agccttgctt ccagatcctg ctagccttgg
    27121 cccacgtact gtaggtaaaa ccaatattgg atgtatcttt acaggtgtca aagatggcgt
    27181 tgaaaagact atctacatct acaatgtttg cgaccatcaa gagtgctatg cagaagtcgg
    27241 gtcacaagca atttcataca cgacaggcgt tccagccatg attgggacaa aattagtcat
    27301 gaacggaact tggaaacaag ctggagtgta taaccttgag gagttagatc cagatccatt
    27361 catggaagct ttgaatgagt atggtttgcc atgggttgtg gttgaaaatc cacaaatggt
    27421 ggactaatga agttagaaca agtaccaaca ccagcctatg ttattgactt ggccaagtta
    27481 gaagctaatt gccgcattct acaatatgta caagaagagg tcggttgcaa ggtcttgctt
    27541 gcccagaagg catattccct ctacaaaact tatcccttga ttagccagta tctatcaggt
    27601 acgacagcta gtggactcta tgaggccaaa ttggcaaggg aagaatttcc tggtgaagtc
    27661 catgtatttg cgcctgcttt caaggatgca gacttggagg aattgcttgg gataacagac
    27721 catatcgtct ttaactcaga gagacagttg cgtaagcatg gggctcgttg tcgagaggct
    27781 ggtgtcagtg ttggtttgcg cctcaaccct cagtgttcaa ctcaaggaga tcacgcgctc
    27841 tatgaccctt gtgcaccagg ttctcgcttt ggagttacta tagacaagat tccgagtgat
    27901 ttgctagatt tggttgacgg acttcatttt catacccttt gcgagcaggg agcagatgat
    27961 ttacaaacaa ctttgaaagc agtagaagaa cagtttggtc cctacttaca tgaggtaaaa
    28021 tggctcaata tgggtggtgg tcatcatatt acaagagaag gttacgatgt ggatttgctg
    28081 atttcagaaa tcaagcgtat ccgaaaaact tacaatcttg aaatatatat cgagcctggt
    28141 gaagccattg cgcttaatgc gggttattta gcaactgagg tattagatat tgtagaaaac
    28201 ggtatggaaa tcttggtttt agacgcctct gcgacctgcc atatgcctga tgtacttgag
    28261 atgccctatc gtccaccttt gagaaatggc tttgaggcac aggaaaaagc ccatacctac
    28321 agactttctt ctaatacctg tctgactggc gatgtgattg gtgattatag ttttgaaaat
    28381 ccagtccaaa tcggagacag actttatttt caagacatgg ccatttattc ttttgtcaaa
    28441 aataatacct ttaatggtat tggattgcca agtctctatc tcatggacga acagggagac
    28501 tgtagcttac tcaaagcttt tggctatcaa gactttaaag ggagattatc atgatggaca
    28561 gtccaaaaaa attaggctat cacatgccag cagagtacga accccatcat ggtaccctca
    28621 tgatatggcc gactcgacca ggatcatggc cttttcaagg aaaggctgct aaaagagcat
    28681 ttactcagat catcgagacc atagcagaag gggaaagagt ctatcttttg gtggagcagg
    28741 cctatctatc tgaagcccaa tcctatcttg gagacaaggt tgtttattta gacattccca
    28801 ccaatgatgc ctgggcgcgt gatactggcc caaccattct cgtcaatgat aaaggtaaga
    28861 aattagccgt ggattgggcc ttcaatgctt ggggaggcac ctatgatggt ctttatcaag
    28921 attatgaaga ggatgaccaa gtagccagtc gttttgctga ggccttggaa aggcctgtct
    28981 atgatgctaa accttttgta ctggaaggag gcgcaatcca tagcgatggt caaggaacta
    29041 ttctcgtaac tgaaagttgc ttgcttagtc ctggtcgcaa tcctaacttg actaaagagg
    29101 agattgaaaa cacattatta gaaagtcttg gtgctgaaaa agttatttgg cttccttatg
    29161 gtatttatca ggatgaaacc aatgaacacg tcgataatgt tgctgccttt gttggtcctg
    29221 ctgagcttgt tttggcttgg acagatgacg aaaatgatcc ccagtatgcc atgtcaaaag
    29281 cagatctcga actcttagaa caggaaacag atgcaaaagg ttgtcacttc accattcata
    29341 aattgcctat ccctgcagtt cgacaagttg tgacagaaga agatttgcca ggctacatct
    29401 atgaagaagg agaagaagag cgatacgcag gtgaacgact agcagcttcc tacgtaaact
    29461 tttatatcgc caacaaggct gtcttggttc cacagtttga ggatgtaaac gaccaagtgg
    29521 ccttagatat cctcagcaag tgtttcccag accgtaaagt tgtcggaata ccagccagag
    29581 atattctctt aggtggtggc aatatccact gtatcaccca acaaattcca gaataggaga
    29641 aaaagatgag aaatgtaaga gttgcaacca ttcagatgca atgcgctaag gatgtggcaa
    29701 caaatatcca aaccgcagag cgtttagtac gtcaggctgc tgagcaagga gcccaaatta
    29761 ttctcttgcc cgagttgttt gaacatccct atttctgtca ggaacgtcag tatgactact
    29821 accagtatgc ccaatctgta gcggaaaata ctgccattca gcattttaag gtgattgcta
    29881 aggaactaca agttgtttta ccaatcagtt tctatgaaaa agatggtaat gtcttgtata
    29941 actctattgc cgtcattgat gcagatgggg aagtgctggg cgtttatcga aagacccaca
    30001 taccagatga ccattattat caagaaaaat tctatttcac gcctggtaac actggtttca
    30061 aggtctggaa tactcgctat gccaagattg gtatcggtat ctgttgggat caatggttcc
    30121 ctgaaacagc gcgctgtctt gcattgaatg gtgctgaatt gctcttttat cctacagcta
    30181 tcggttcaga gccaattttg gatacagata gttgtggtca ctggcaacgt actatgcaag
    30241 ggcacgcagc agcgaatatt gttccagtca tcgcagccaa tcgttatggt ttagaggagg
    30301 ttactcctag tgaggaaaat ggcggacaga gttccagtct tgacttctac ggttcctcct
    30361 ttatgacgga tgaaacagga gctattctag aacgagctga aagacaagaa gaagctgttc
    30421 tgttagctac ttatgaccta gacaagggag caagtgaacg tctaaactgg ggcttgtttc
    30481 gagatagaag accagaaatg tatagacaaa ttacagatta gtgtgggaga aatgagagat
    30541 tcattctact agactaactt cttattagca actataagat actatggcat ctagtaaatc
    30601 gatttttatg attcgctatt cttgtctatt gattagtccg tattttaaaa tattagcaaa
    30661 aaagcaaata gcagtaactt ctgtctattt gcttttcttt tttatagaat atatttctca
    30721 atagcacgcg caacgccgtc ttcttcgttg cttgaggtaa cggcatccgc aagagatttg
    30781 acataatcgc tggcagttcc cattgcaatc ccaagccctg caaactggag catttcgata
    30841 tcgttattag catcgcccat ggccataatc tctgaggaat caatcttcaa aatctcagct
    30901 agtcgtgaaa gagcagtagc ctttgtcgtt ccaagcggca ttgcttcata aatgacaggc
    30961 tgcgaacgaa ctccactgaa tcgttggcaa agctcttcag caaaacgctg ctcaaaatcg
    31021 tctgtttgtt cttttgttcc taaaaacata ccttggaaca tccggaactt tccactagtc
    31081 gcttcttcaa gagaaatttc agtcaggtct gaaaatacta gtttagcatc attttcaata
    31141 acttgattgg gcttgccacc gagaacaaaa taatgtgact cgtcaaaaag tgtcaactga
    31201 acatcactct tttcagcaag gtcatagagg tattcgatgt cagctggact cagttcttgc
    31261 cagtcaacca agccccagtc gctagtctgg tgagttgaac aaccgttgtt aacaatcaca
    31321 tactcattct ggaggtcgag tcccagtttt ttgtagtagg ggaggacacc gaaaaggggg
    31381 cgacccgtac agagaaccag tttgacacct ttttcaatgg ctttgtgaat agcagtaatg
    31441 tgagcttgtg ggatttcctt ggcttcattg aggagggtgc cgtccatatc caaggctagt
    31501 agtttaatca taggtcttcc ttctttatct tttgctatta ttatagcata ttttggagaa
    31561 gaaattgata gaaagcttga gactaattga ttttgcagtt taggacgttt cgatgacaat
    31621 tcaagatttg aagaggatat ttggcaaaga tatgctatac taaacttgtc aacgttgcaa
    31681 ctagacaagc ataaaaaaac tagcttaaaa tagttttttt gtaagtaggt atgagtagta
    31741 gattactcaa ctaatctgaa gaataatgga ggaaatatat catgatttta atgacaaaaa
    31801 atataaatct aacaaatgaa gaattagagc tgatacaagg tggagcagat ccctatggta
    31861 aaaatcctaa tggtaggtac gattgggaaa tagaaccagt attaactctg ccggttcatg
    31921 gattttgtcc cagaggcacc tatgatttag gatatattgg aggaggcaat catctttgca
    31981 aaggaagtgc tgcgagattt taagtaaaat ttattaggaa tatgaagaaa caagtggaga
    32041 aagcagagaa tttaatatga aaaaacgggc tattcaaatt ttactagcat tgtccttaat
    32101 tttttacaaa tcaacttggt tttggagagt tttcaatcac ctcgcaaagc cctatctacc
    32161 agcaagtcgt gaattttttc agattctgct tttgatggag agcggagttc ttttcttagc
    32221 ggtcatctat ctactggttt ttgcaggaaa gaagattttt catttcaagt ggcagctgag
    32281 gtactttatc taccttttac tgggctacat catttcgtat atgtctgact ttctcttttc
    32341 gtatttcata tccccgcctt caaatcaaat ttctttgaat gaaacgatag aaatgatggg
    32401 acgacaggag ttcccttatt tcttgctcat cgtttgcttc atcgccccta ttgctgagga
    32461 attgatttat cgcggtgtgc ttatgacaac ctttttcaaa aactcgcctt ggtacggaga
    32521 tgtcttgctt tctgctatta ttttcggtta tattcatatc aattttgctt taactcctct
    32581 tgcttttttc atttatgcta gtggaggcct tattttggct ctattgtatc gcatgaccaa
    32641 aagtctctac tatccaatac tagtacatat tctcatcaat atcactgcct tctggaatgt
    32701 atggttactc ctattttcag gaagttagct tactaaaaca atgtcggaac tttccggcat
    32761 tttctttttt cacaaatagt caacgttttt ctttccgata ctgaagtggt gtgtagccac
    32821 ttattttttt gaattgattt tgaaaataag gttggcttga gaaaggcaga tagtgaagat
    32881 agttaagaag aataggatgt tcttttttcc tttttggaaa acttctaaaa tatggtataa
    32941 tgaaaagata aagaagttgg gggtagaaga tgaacattca acaattacgc tatgttgttg
    33001 ccattgccaa tagtggtact ttccgtgaag ctgctgaaaa gatgtatgtt agtcagccga
    33061 gtctgtctat ttctgttcgt gatttggaaa aagagttggg ttttaagatt ttccgtcgga
    33121 ccagctcagg gactttcttg acccgtcgtg ggatggaatt ctatgaaaaa tcgcaagaat
    33181 tggttaaagg atttgatatt tttcaaaatc agtatgccaa tcctgaagaa gaaaaagatg
    33241 aattttccgt tgctagccag cactatgact tcttaccacc aactattacg gccttttcag
    33301 agcgctatcc tgactataag aacttccgta tttttgaatc aactactgtt caaatattag
    33361 atgaagtggc gcaagggcat agtgagattg ggattatcta cctcaacaat caaaataaaa
    33421 aggggattat gcaacgggtt gaaaagttag gtctggaggt catcgaattg attcctttcc
    33481 atacccatat ttatctctgt gagggtcatc ctttagccca gaaagaggaa ttagtcatgg
    33541 aggatttagc ggatttacca acggttcgtt tcactcaaga gaaagacgag tacctttatt
    33601 attcagagaa ctttgtcgat accagcgcta gctcacagat gtttaatgtg acagaccgtg
    33661 ccaccttgaa tggtattttg gagcggacgg acgcctatgc gacaggttct ggatttttag
    33721 atagtgacag tgttaatggc attacagtta ttcgtctcaa ggataaccta gataaccgca
    33781 tggtctatgt taaacgtgaa gaagtggagc ttagtcaagc tgggactctc ttcgtagaag
    33841 tcatgcaaga atattttgat caaaagagga aatcatgaaa aaaagagcaa tagtggcagt
    33901 cattgtactg cttttaattg ggctggatca gttggtcaaa tcctatatcg tccagcagat
    33961 tccactgggt gaagtgcgct cctggattcc caatttcgtt agcttgacct acctgcaaaa
    34021 tcgaggtgca gccttttcta tcttacaaga tcagcagctg ttattcgctg tcattactct
    34081 ggttgtcgtg ataggtgcca tttggtattt acataaacac atggaggact cattctggat
    34141 ggtcttgggt ttgactctaa taatcgcggg tggtcttgga aactttattg acagggtcag
    34201 tcagggcttt gttgtggata tgttccacct tgactttatc aactttgcaa ttttcaatgt
    34261 ggcagatagc tatctgacgg ttggagtgat tattttattg attgcaatgc taaaagagga
    34321 aataaatgga aattaaaatt gaaactggtg gtctgcgttt ggataaggct ttgtcagatt
    34381 tgtcagaatt atcacgtagt ctcgcgaatg aacaaattaa atcaggccag gtcttggtca
    34441 atggtcaagt caagaaagct aaatacacag tccaagaggg tgatgtcgtc acttaccatg
    34501 tgccagaacc agaggtatta gagtatgtgg ctgaggatct tccgctagaa atagtctacc
    34561 aagatgagga tgtggctgtc gttaacaaac ctcagggaat ggttgtgcac ccgagtgctg
    34621 gtcataccag tggaacccta gtaaatgccc tcatgtatca tattaaggac ttgtcgggta
    34681 tcaatggggt tctgcgtcca gggattgttc accgtattga taaggatacg tcaggtcttc
    34741 tcatgattgc taaaaacgat gatgcgcatc tagtacttgc ccaagaactc aaagataaaa
    34801 agtctctccg caaatattgg gcgattgttc atggaaatct gcctaatgat cgtggtgtaa
    34861 ttgaagcgcc gattggccgg agtgaaaaag accgtaagaa acaggctgta actgctaaag
    34921 ggaagcctgc agtgacgcgt tttcacgtct tggaacgctt tggcgattat agcttagtag
    34981 agttgcaact ggagacaggg cgcactcatc aaatccgtgt ccacatggct tatatcggcc
    35041 atccagtcgc tggtgatgag gtctatggtc ctcgcaagac tttgaaagga catggacaat
    35101 ttcttcatgc caagacttta ggttttactc atccgagaac aggtaagacc ttggaattta
    35161 aagcagatat cccagagatt tttaaggaaa ccttggagag attgagaaag taagaatgaa
    35221 aaagaaatta actagtttag cacttgtagg cgctttttta ggtttgtcat ggtatgggaa
    35281 tgttcaggct caagaaagtt caggaaataa aatccacttt atcaatgttc aagaaggtgg
    35341 cagtgatgcg attattcttg aaagcaatgg acattttgcc atggtggata caggagaaga
    35401 ttatgatttc ccagatggaa gtgattctcg ttatccatgg agagaaggaa ttgaaacgtc
    35461 ttataagcat gttctaacag accgtgtctt tcgtcgtttg aaggaattga gtgtccaaaa
    35521 acttgatttt attttggtga cccataccca cagtgatcat attggaaatg ttgatgaatt
    35581 actgtctacc tatccagttg accgagtcta tcttaagaaa tatagtgata gtcgtattac
    35641 taattctgaa cgtctatggg ataatctgta tggctatgat aaggttttac agactgctgc
    35701 agaaaaaggt gtttcagtta ttcaaaatat cacacaaggg gatgctcatt ttcagtttgg
    35761 ggacatggat attcagctct ataattatga aaatgaaact gattcatcgg gtgaattaaa
    35821 gaaaatttgg gatgacaatt ccaattcctt gattagcgtg gtgaaagtca atggcaagaa
    35881 aatttacctt gggggcgatt tagataatgt tcatggagca gaagacaagt atggtcctct
    35941 cattggaaaa gttgatttga tgaagtttaa tcatcaccat gataccaaca aatcaaatac
    36001 caaggatttc attaaaaatt tgagtccgag tttgattgtt caaacttcgg atagtctacc
    36061 ttggaaaaat ggtgttgata gtgagtatgt taattggctc aaagaacgag gaattgagag
    36121 aatcaacgca gccagcaaag actatgatgc aacagttttt gatattcgaa aagacggttt
    36181 tgtcaatatt tcaacatcct acaagccgat tccaagtttt caagctggtt ggcataagag
    36241 tgcatatggg aactggtggt atcaagcgcc tgattctaca ggagagtatg ctgtcggttg
    36301 gaatgaaatc gaaggtgaat ggtattactt taaccaaacg ggtatcttgt tacagaatca
    36361 atggaaaaaa tggaacaatc attggttcta tttgacagac tctggtgctt ctgctaaaaa
    36421 ttggaagaaa attgatggaa tctggtatta ttttaacaaa gaaaatcaga tggaaattgg
    36481 ttgggttcaa gataaagagc agtggtatta tttggatgtt gatggttcta tgaagacagg
    36541 atggcttcaa tatatggggc aatggtatta ctttgctcca tcaggggaaa tgaaaatggg
    36601 ctgggtaaaa gataaagaaa cctggtacta tatggattct actggtgtca tgaagacagg
    36661 tgagatagaa gttgctggtc aacattatta tctggaagat tcaggagcta tgaagcaagg
    36721 ctggcataaa aaggcaaatg attggtattt ctacaagaca gacggttcac gagctgtggg
    36781 ttggatcaag gacaaggata aatggtactt cttgaaagaa aatggtcaat tacttgtgaa
    36841 cggtaagaca ccagaaggtt atactgtgga ttcaagtggt gcctggttag tggatgtttc
    36901 gatcgagaaa tctgctacaa ttaaaactac aagtcattca gaaataaaag aatccaaaga
    36961 agtagtgaaa aaggatcttg aaaataaaga aacgagtcaa catgaaagtg ttacaaattt
    37021 ttcaactagt caagatttga catcctcaac ttcacaaagc tctgaaacga gtgtaaacaa
    37081 atcggaatca gaacagtagt agaaaagaag gttttagggc cttctttttc ctatcaactc
    37141 ttttctattt cctgttattc atgttataat ggataaatat gaataatcgg agtgagacta
    37201 tgaaatacaa acggattgtc tttaaggtgg gtacttcttc tctgacaaat gaggatggaa
    37261 gtttatcacg tagtaaggta aaggatatta cccagcagtt ggctatgctg cacgaggctg
    37321 gtcatgagtt gattttggtg tcttcaggtg ccattgcggc tggttttgga gccttaggat
    37381 ttaaaaagcg tccgactaaa attgctgata aacaggcttc agcagcggta gggcagggac
    37441 ttttgttgga agaatatacg accaatcttc tcttgcgtca aatcgtttct gcacaaatct
    37501 tgctgaccca agatgacttt gtggataagc gtcgttataa aaatgcccat caggctttgt
    37561 cggttttgct caaccgtggg gcaattccta tcatcaatga gaatgatagt gtcgttattg
    37621 atgagctcaa ggttggggac aatgacactc taagtgctca agtagcggcg atggtccaag
    37681 cagacctttt agttttcttg acagatgtgg acggtctcta tactggaaat cctaattcag
    37741 atccaagagc caaacgcttg gagagaatcg agaccatcaa tcgtgagatt attgatatgg
    37801 ctggtggagc tggttcgtca aacggaactg ggggtatgtt aaccaaaatc aaggctgcaa
    37861 ctatcgcgac ggaatcagga gttcctgttt atatctgctc atccttgaaa tcagattcca
    37921 tgattgaggc ggcagaggag accgaggatg gttcttactt tgttgctcaa gagaaggggc
    37981 ttcgtaccca gaaacaatgg cttgccttct atgctcagag tcaaggttct atttgggttg
    38041 ataaaggggc tgcggaagct ctctctcaac atggaaagag tcttctctta tctggtatcg
    38101 ttgaagcaga aggagtcttt tcttacggtg atatcgtgac agtatttgat aaggaaagtg
    38161 gaaaatcact tggaaaagga cgcgtgcaat ttggagcatc tgctttggag gatatgttgc
    38221 gttctcaaaa agccaagggt gtcttgattt accgtgacga ctggatttcc attactcctg
    38281 aaatccaact actttttaca gaattttaga ggtaaactat ggtgagtaga caagaacaat
    38341 ttgaacaggt acaggctgtt aaaaaatcga ttaacacagc tagtgaagaa gtgaaaaacc
    38401 aagccttgct agccatggct gatcacttag tggctgctac tgaggaaatt ttagcggcta
    38461 atgccctcga tatggcagcg gctaagggga aaatctcaga tgtgatgttg gatcgtcttt
    38521 atttggatgc agatcgtata gaagcgatgg caagaggaat tcgtgaagtg gttgccttac
    38581 cagatccaat cggtgaagtt ttagaaacaa gtcagcttga aaatggtttg gttatcacaa
    38641 aaaaacgtgt agctatgggt gtcatcggta ttatctatga aagccgtcca aatgtgacgt
    38701 ctgatgcggc tgctttgact cttaagagtg gaaatgcggt tgttcttcgt agtggtaagg
    38761 atgcctatca aacaacccat gccattgtca cagccttgaa gaagggcttg gagacgacta
    38821 ctattcatcc aaatgtgatt caactggtgg aggatactag ccgtgaaagt agttatgcta
    38881 tgatgaaggc caagggctat ctagaccttc tcattcctcg tggaggagct ggcttgatca
    38941 atgcagtggt tgagaatgcg attgtacctg ttatcgagac agggactggg attgtccatg
    39001 tctatgtgga taaggatgca gacgaagaca aggcgctgtc tatcatcaac aatgctaaaa
    39061 ccagtcgtcc ttctgtttgt aatgccatgg aggttctgct ggttcatgaa aacaaggcag
    39121 caagcatcct tcctcgcttg gatcaaatgc tggttgcaga gcgtaaggaa gctggactgg
    39181 aaccaattca attccgcttg gatagcaaag caagccagtt tgtttcaggt caagcagctg
    39241 agacccaaga ctttgacacc gagtttttag actatgtcct tgctgttaag gttgtgagca
    39301 gtttagaaga agcggttgcg cacattgaat cccacagcac ccatcattcg gatgctattg
    39361 tgacggaaaa tgctgaagct gcagcatact ttacagatca agtggactct gcagcggtgt
    39421 atgttaatgc ctcaactcgt ttcacagatg gaggacaatt tggtcttggt tgtgaaatgg
    39481 ggatttctac tcagaaattg cacgcgcgtg gtccaatggg cttgaaagag ttgaccagct
    39541 acaagtatgt ggttgctggt gatgggcaga taagggagta agagatgaag attggattta
    39601 tcggtttggg gaatatgggt gctagcttgg caaaatctgt cttgcagact aggacgtcag
    39661 atgagattct ccttgccaat cgtagtcaag ctaaggtaga tgctttcatt gcagactttg
    39721 gtggtcaggc ttccagcaat gaagaaatgt ttgcagaagc agatgtgatt tttctaggag
    39781 ttaagcctgc tcagttttct gaactgcttt ctcaatacca gaccatcctt gaaaaaagag
    39841 aaagtcttct tttgatttcg atggcagctg gattgacctt agaaaaacta gcaagtctta
    39901 tcccaagtca acaccgaatt attcgtatga tgcctaatac ccctgcttct atcgggcaag
    39961 gagtgattag ttatgccttg tctcctaatt gcagggctga ggacagtgag ctcttttgtc
    40021 agcttttatc caaggctggt ctcttggttg aattaggaga aagcttaatc aatgcagcga
    40081 caggtcttgc aggctgtgga ccagcctttg tctatctctt tattgaggct ttggcagatg
    40141 caggtgttca gacgggatta ccacgagaaa cagccttgaa aatggcagcc caaactgtgg
    40201 taggagctgg gcaattggtc ctagaaagcc agcaacatcc tggagttttg aaagatcaag
    40261 tttgtagtcc aggcggttcg actattgctg gcgtagcaag cttagaagcg catgcttttc
    40321 gaggcatagt catggaggca gttcatcaag cctataaacg aacacaagaa ctaggtaaat
    40381 aagaggtagc tttgactgcc tcttttatgg tggctgaaat gagaagacac aaaaagattg
    40441 tcacaaactc ctattttttt gatagaatag aagtagtaaa aaagaaatga gttagacatg
    40501 tcaaaaggat ttttagtctc tcttgaggga ccagagggag caggcaagac cagtgtttta
    40561 gaggctctgc taccaatttt agaggaaaaa ggagtagagg tgttgacgac ccgtgaacct
    40621 ggcggagtct tgattgggga gaagattcgg gaagtgattt tggatccaag tcatactcag
    40681 atggatgcga agacagagct tttgctctat attgccagtc gcagacagca tttggtggaa
    40741 aaagttcttc cagcccttga agctggcaag ttggtcatca tggatcgttt tatcgatagt
    40801 tctgttgcct atcagggatt tggtcgtggc ttagatattg aagccattga ctggctcaat
    40861 cagtttgcga cagatggcct caaacccgat ttgacactct attttgacat cgaggtggaa
    40921 gaagggctgg ctcgtattgc tgctaatagt gaccgcgagg ttaatcgttt ggatttggaa
    40981 gggttggact tgcataaaaa agttcgtcaa ggctaccttt ctcttctgga taaagaggga
    41041 aatcgcattg tcaagattga tgctagtctc cctttggagc aagttgtgga aactaccaag
    41101 gctgtcttgt ttgacggaat gggcttggcc aaatgaaaca agatcaacta aaggcttggc
    41161 aaccagctca gtttgaccgt tttgtccgta tcttagaaca agaccagctc aatcacgcct
    41221 atctcttttc aggtttcttt ggaagcttgg aaatggcgca atttttagct aagagccttt
    41281 tttgtacgga taaagttggc gtcttaccat gtgagaaatg ccgaagttgc aagctgattg
    41341 aacaggaaga gtttccagat gtcaccttga ttaagccagt caatcaggtc atcaagacag
    41401 aacgcattcg ggaattggtg ggacagtttt ctcaagcagg gattgaaagc cagcaacagg
    41461 tctttatcat cgagcaagcg gataaaatgc atcccaacgc agccaattct ctgctcaagg
    41521 tcatcgaaga accccagagt gaagtttata ttttcttctt gactagcgat gaggaaaaga
    41581 tgttaccgac aatccgaagt cggactcaga tcttccactt taaaaagcaa gaagaaaaac
    41641 ttatcttact cttagaacaa atgggacttg ttaagaaaaa agcgactctt ttagctaagt
    41701 ttagtcaatc gcgagctgaa gcagaaaagt tggcacatca ggcaagtttt tggaccttgg
    41761 tcgatgaaag tgaacgcctg ctgacttggt tagtagctaa gaaaaaagaa agttatctac
    41821 aggttgccaa attagccaac ttggcagatg ataaggaaaa acaggatcag gttttacgga
    41881 ttcttgaagt tctctgtggg caggacctct tgcaggtaag agtaagagtg attctacaag
    41941 atttactaga agctagaaaa atgtggcaag ctaatgtcag ctttcaaaat gccatggaat
    42001 atctggtctt gaaagaaata taaactcaaa aatgaatgat aaagaaagga aagggctgtt
    42061 ttatggacaa aaaagaatta tttgacgcgc tggatgattt ttcccaacag ttattggtaa
    42121 ccttggccga tgtggaagcc atcaagaaaa atctcaagag cctggtagag gaaaatacag
    42181 ctcttcgttt ggaaaattct aagttgcgag aacgcttggg tgaggtggaa gcagatgctc
    42241 ctgtcaaggc caagcatgtt cgtgaaagtg tccgtcgcat ttaccgtgat ggatttcacg
    42301 tatgtaatga tttttatgga caacgtcgag agcaggacga ggaatgtatg ttttgtgacg
    42361 agttgctata cagggagtag gcatgcagat tcaaaaaagt tttaaggggc agtctcccta
    42421 tggcaagctg tatctagtgg caacgccgat tggcaatcta gatgatatga cctttcgagc
    42481 tatccagacc ttgaaagaag tagattggat tgctgctgag gatacgcgca atacaggtct
    42541 tttgctcaag cattttgaca tttccaccaa gcagatcagt tttcatgagc acaatgccaa
    42601 ggaaaaaatt cctgatttga ttggtttctt gaaagcaggg caaagtattg ctcaggtctc
    42661 tgatgccggt ttgcctagca tttcagaccc tggtcatgat ttagttaagg cagctattga
    42721 ggaagaaatt gcagttgtga cagttccagg tgcctctgca ggaatttctg ccttgattgc
    42781 cagtggttta gcgccacagc cacatatctt ttacggtttt ttaccgagaa aatcaggtca
    42841 gcagaagcaa ttttttggct tgaaaaaaga ttatcctgaa acacagattt tttatgaatc
    42901 acctcatcgt gtagcagaca cgttggaaaa tatgttagaa gtctacggtg accgctccgt
    42961 tgtcttggtc agggaattga ccaaaatcta tgaagaatac caacgaggta ctatctctga
    43021 gttattagaa agcattgctg aaacgccact caagggcgaa tgtcttctca ttgttgaggg
    43081 tgccagtcag ggtgtggagg aaaaggacga ggaagacttg ttcgtagaaa ttcaaacccg
    43141 catccagcaa ggtgtgaaga aaaaccaagc tatcaaggaa gtcgctaaga tttaccagtg
    43201 gaataaaagt cagctctacg ctgcctacca cgactgggaa gaaaaacaat aaagggagac
    43261 aggatgtaat aattctgtct gtttctgttt aacttaatta gtgatgataa tattcggagt
    43321 ctaaataata gaattgattg agtagtgaat aaataaaaac aatgttcatt cagtttacgt
    43381 tgaatatata taatgtactc tattagaatt atttttaagt acgcagtatg gtataattat
    43441 atatgagaaa atagtgtgga gtttatcagt tgaaaaaata taacattgta gatttatttt
    43501 caggagcagg tggtctatct tatggattcg agatggctgg atttaatgtt ctattaggaa
    43561 ttgataatga cgaaaaagcc ttagaaacct ttcaaaaaaa tcatcagaat tcagaaatat
    43621 tatgtggaga tattgcgaat atatcttatg aggaagatat aaaaccaata attggagaac
    43681 aaaaaattga cataattgta ggtggtcccc cttgtcaggg gatgtcgctt tctggaccta
    43741 gaagatttga tgatccaagg aacaaacttt atttgtctta tattcgattg gttcgagaaa
    43801 tacagccaac tgcttttgtc attgaaaatg tgattgggat tgttagtttg tttaaagggc
    43861 aaataaaaga tactattata gaagaatttt cgaaaatggg ttataaggtt cagtttaaag
    43921 tgttgctggc ctctgactat ggagttcctc aaaatagaaa acgtgttatt tttgtgggga
    43981 cgaggaatga tggatttgaa tatcctgaag cattgggaac aatcattaca acagagatgg
    44041 caatttctga tttaccaaca ttagaaaatg aacttggcga gatagaaatg tcttatgttt
    44101 cagaaccaca aaatgactat caaaaactaa tgcgaaaacg ttcaaacgta gttttgaacc
    44161 acgttgcagc caagcattca gaaaaagtga taagtacaat tgcccttgtc cctgacggtg
    44221 gaaattataa aaatctcccg aaggaattac gagaaacaag aaaatttaat gtcgcttgga
    44281 cacgatttgc tagttggaag ccagctccta cgattgatac ggggcataga catcatttcc
    44341 actataagta taatcgtgtg ccaacagtga gggaatctgc tcgtctacaa tcttttccag
    44401 atgattttat cttttacgga agtaaaacac agcaatttag acaagttggt aatgctgttc
    44461 ctcctttaat ggctcagcag attgcaaaca atttactgaa atatttaaaa aataacgaag
    44521 agtaactatg tatcaagttc cagagaaata ttattttaga ctacatcacc caagacctcg
    44581 ttttaaaaat gatgtcgaaa atgtacttgt ttatatggca acgaatattt cttatttggg
    44641 aatattgcct aaaaaggaat ttagtcagca actaaatgac attatcaaac aatatgcagg
    44701 aaatgcagat aaaacagaga aaacaatcaa taattggcga acagagattt cttctttgtt
    44761 tggaatgatg attgagaaag aaggctttgt ctattcagga aatagggcta aggaattgac
    44821 tgaagaccaa gaccttattc gcttttttaa aacctttttg tataattttg aatatcctgg
    44881 tgggcatcta aaagataacg agattgttaa actttgtcaa atcggagttc aatttaagcc
    44941 agctcagtat ctactggaac tatttacaga agcctcacaa gctgaagaaa aaactattta
    45001 cctcaccgat gaagaagtcg cccattgtat ctttaatgat ttgagatgta ctcgtgatag
    45061 agagcctgtt ttggaaatat ggaatcgtat caaagagaat agagcgtcta aagtagctta
    45121 cgatactaaa ggagatgtta ttcgatatgc caaagatatt ttagattaca tggtgatagc
    45181 gagtttacta actgttcaag gtggtaggta taaaataaat tctatggaag agcaagcaat
    45241 aaatgacttt ttgcaatcag atgctacctt tgatggctat gctcaattta ttggaaatgc
    45301 ttctacaaca attgaagatg ttcgaaattt tagaagtgct tggttcgaat atgtcaatcg
    45361 tgatttagga gatattgatt ttaggacaaa ctttaatctc taccttccaa gtgatattga
    45421 ttttactgaa gagaaaacag atattatcgg acatctaact gaacacatcg aatacagcga
    45481 gaaaatatct accgctgttg tagggagttc gggagaagct attgttatca atcatgaaaa
    45541 acaaaaatta cgagaacatg ggcaagaaca gttgctccat ctggtgaatt ttattccaac
    45601 acagtttggt gtcggctacg atgttcaatc ttttgagtgt gatgattctg agctgagaaa
    45661 gtatattgaa gtcaaaacaa ctgtcagcaa tgcttctatt acttttaatt cgtttcatat
    45721 cacaccaaac gaatggcgaa ctgctaaatc tgtgcgtgat agatactata tttatcgttt
    45781 gcagatttct aaacatagca aaaaattgtt tattatcaag aatttgtatg agttagtcaa
    45841 aaatgagaag atgcttctga ttgagagaaa agatggatat gatgtccgtt tttcatcgtc
    45901 agttggcttt gaggagaatt taatttgaag aaactaaaaa ttgcctctct ttttagtgga
    45961 gggggtggaa cggatattgg ttttgctggt ggatttgatt ttttaggtaa acattatgcc
    46021 gacaatcaaa ttgagattgt ctatgcaaat gatattgaag acagtgccaa taaaatgttt
    46081 gaaaagaatt ttggtgttac tccagacaat cgaaatatcc gagaaataaa atcagatgaa
    46141 atcccatctt tcgatatttt aacgggaggt tttccttgtc aatcattttc tgttagtgct
    46201 caaaatccga aacgcttagg aataaaagac gaaaaaggga cattgttttt tgagatggtg
    46261 cgagtgttaa aagctcatca accaaaagca ttttttgccg aaaatgttaa gggaattttg
    46321 tctgcaaaca ataaagaagc ctttcctcta attattgaag agttcgaaaa agctggttat
    46381 aatgtttctt ataaactttg cgtagccacc aaatacggcg ttccgcaaaa gagagagcgt
    46441 gtgtttattg ttggtattcg aaaggatttg aattttactt ttgaatttcc tgaagagcct
    46501 attcaaaatg tagaagatta tacaccacta aaagtaattc ttcagcaaga tattgatgaa
    46561 aagtattatt ttagtgagag ggctgtgcaa ggaatgctaa atagtaaatc tggcaaaaaa
    46621 atgaataaag gacgagcaca agacattgaa cagccgagta atacggttag ttctcactta
    46681 gcaaaagtat ccttaaatag cactgaccct gttttgttag aaaatggacg ttaccgtcgc
    46741 tatactccaa gagaggttgc acgtattcag tcgtttccag aaaactatga attgcttggt
    46801 tcagaaggtg ctcaatatag aatgctgggg aatgctattc caccagtaat gatgtggtat
    46861 attgctgaaa agttagtgtc agatttacga aatagtgatg taattgcaaa gcaacagaaa
    46921 ctcgaagaaa gttttggtca actggatttg tttgaagcga gttgatgttt taaatctagg
    46981 gaacttgata tggaattaaa ttttcaagat aagagtttta taaaagtatt ttttaatagt
    47041 gacggttatg tattaaattt ttctaactct acttttgcta attttacttt taattcagta
    47101 ggagtaaata ttcaagagaa atatggaggt tcaaaaggga aagctttaca ggcttttgta
    47161 gataacgaac cagatgaact ggttttaaaa ttggctttag atttacttag atattatgaa
    47221 gaccttcctg actcatatta cgagaaaact gaagagagga actctcaggc attgaaattg
    47281 aaagagagac tttcgaaata tgaagtctca caaatagcct acttaaataa tgctgctaaa
    47341 tctttatctg actattttga tagcgactat atagataagc aaatggggat tatgaatgaa
    47401 atgatttctc gctctccagc ggacgctatt ggaaaagcta aggaattgtt ggaatcgtgt
    47461 tttaaacata ttttagacca tgaaaaaatt gagtattcta attctaatga tattgcaact
    47521 ttgcaaaaga aagtctttaa atttttaaac ttggattcta atgaaaatat ttcagcaaaa
    47581 aataatcaag atgtgaaggt ggttctaagt ggtttgaatc aaattatcaa gggtattaac
    47641 aatcttagaa atgataaagg tgatggtcat ggtaagggag ctaactttat agaattgcca
    47701 ccaaggtatg cttcagttgt tgtaggttct gcattaacgg tagtgtcatt tgtttgggaa
    47761 acataccaag ataagcaaaa atagtaaagg agggagattt aatgtcgaaa aatcaagaaa
    47821 aattacactt tcaacttaaa aaatttatag taaatgtagg ttggactcac aaaattcatg
    47881 cggttagaat tgacgagtta gaaagctata ttcgatggtt tagaatagca acaataatca
    47941 tttctggagt tgtctcttct ggcttagttg gaatactttg gtttgatgaa tattggataa
    48001 agcttgttac agtattttta tcattagtca cgacaataat ttttagcatc acaaaggagt
    48061 ttaactttga ggaacgacta gctttggaga ggaaatctgt tgatgagctt tggaatctta
    48121 gagtgttagc tgaaattctt ttatctgagg tggtttacaa tggaaaacca tccagtgaaa
    48181 tccaagaatt tttcgaagaa ttaaaatttc gaagagatgc tacttatagt caactttcta
    48241 atgcttctcc caaaaatgta tccaaggctt caaaactaat aaaatcgaga aaagataatg
    48301 attatgagga ggattataga tactttattc caaaagaatt gatggaaatt aaggaggaag
    48361 agtaatgtct ttatctaatg attttaaaga attttgcgaa gacgaactcc ccatgacgga
    48421 tgaggaatgg gaaaaatggg agaatagatt aaaagagatt acgaaacgac ttaatcgaaa
    48481 attttattcc ttagatgagc ttgacgatca agaaactgac aacggtttga ttgttggtag
    48541 tgtggggaga acgacggctg ttcgaaatgt tagtgatttt gattatattt tttctctacc
    48601 atcagaagtg tatagatgat ttgattctta tgagggcaat ggtcaatcag cactcctaca
    48661 ggaaataaaa aacgaattac taaaaagata cccaaataca aaaataaaag gagacggaca
    48721 ggtcgttgtt attgattttt cggatggtgg aaaaattgag ttagttccag ctttcgaaaa
    48781 atctgatggt aattttaaat atcctgattc tcgtaacgga ggttcttgga aaactactaa
    48841 accaaagtct gaaattgaaa aatgcaaatc tttaaattcc aattttaata gtcatttttc
    48901 taacttaaca aggctcatac gacaatggaa aaatcatatg ggcttttcat ttaaggggtt
    48961 gttgatagat actttgatat ctgatttaat tgatgataaa ggtatttctg aaatatatta
    49021 ttctgattat aatattctct tgaaagatat ttttgaatac ttttcaaatc aagataaaaa
    49081 tagagagtat tggtatgctt taggtagtaa tcaaaagatt tataataatg atggagcaaa
    49141 atttgtcaat aaagctaagc aggctctaaa gaaaatagaa gacgcttcag aagagaaact
    49201 tactgaagtt tatagacagc tatttggtag aaaattcgct caatctactt ctacaacaaa
    49261 tcgagcttcg aatgaagaat ttattgatga attgtttaat gttaatatcg aatataatat
    49321 tgttttggag tgtgaaatta cacaagatgg ttttcgaaaa gcacttcttt cagacttttt
    49381 aaaaagtaga tttaagatta aaaatagaaa atctcttgat tttgaaatta taaaatcaga
    49441 tattccagat aatcttttgt ctgatgttaa atattattgg aaagtgagaa atattggagc
    49501 tgaggcgatt agaagaaatt gtgagcgtgg tgctattttt tcaggtaaaa taaaacatca
    49561 cgaagattct cagtttaaag gagaccacta tgttgaatgt tatgctgttt tagataatac
    49621 ggttatagca agagatagaa taacagtccc tatcgatccg ttatgtggaa aagattttat
    49681 agagtagcat ataattgatt cttaactgga atactctcta tctctttaca tcaagaaaat
    49741 gactaaacag ggaagtttgc cttcttccct ttttttgtta tactagtaga agaaaaaaat
    49801 agaaagattt gtgggagtga aaaagtccag gggacttttt cagcttgagc aaagaaattc
    49861 gagagcgagg aaagtccggg ggactttttc agcttgagcc aagaaattcg agagcgagga
    49921 aagtctgggg gactttttca gcctgagcca agaaactcga aagcttgtaa gtctgattgg
    49981 ctttttcaat gtgaatctta acttcacact cccaaagagg tattagtgtc gtgtctcaat
    50041 cttatatcaa tgttatcggt gctggtttgg caggttctga agcagcttac caaatcgcag
    50101 agcgtggtat tccagttaaa ctatatgaaa tgcgtggtgt caagtctaca ccccagcata
    50161 aaacagacaa ttttgctgag ttggtttgtt ccaattcttt gcgtggggat gctttgacaa
    50221 atgcagttgg tcttctcaag gaagaaatgc gtcgcttggg ttctgttatc ttggaatctg
    50281 ctgaggctac acgtgttcct gccggtggag cccttgcggt ggatcgtgat ggtttctctc
    50341 aaatggtgac cgaaaaagtg gtcaaccacc ccttgattga agtggtgcgt gatgaaatta
    50401 cagaattgcc aacagatgtt attacagttg tggcgactgg tcccttgact agcgatgccc
    50461 tggctgaaaa gattcatgcc cttaataatg gcgatggctt ctatttctac gatgcagcag
    50521 cgcctattat cgatgtcaac actatcgata tgagtaaggt ctatctcaaa tctcgttatg
    50581 ataagggaga agcagcctat ctcaatgctc caatgaccaa gcaagagttt atggatttcc
    50641 atgaagcctt ggtcaatgcg gaagaagcac cgctcaattc ttttgaaaaa gaaaagtact
    50701 ttgaaggatg tatgccaatc gaagttatgg ccaaacgtgg cattaaaact atgctttatg
    50761 gccctatgaa gccagtcggt cttgagtatc cggacgacta cacaggacct cgtgatggag
    50821 aatttaaaac accttatgcg gttgtgcaac ttcgtcagga taatgcagct ggtagcctat
    50881 acaatattgt tggtttccag acccacctca aatggggaga acaaaagcgt gtcttccaaa
    50941 tgattccggg tcttgaaaat gcggagtttg tccgttatgg tgtcatgcat cgcaattctt
    51001 acatggattc accaaatctt cttgagcaga cttaccgttc caagaaacaa ccaaatctct
    51061 tctttgctgg tcagatgacg ggggtggaag gctatgttga gtcggcggct tcgggcttag
    51121 ttgcgggaat taacgcagct cgtctcttca aggaagaaag cgaggttatt ttccccgaga
    51181 cgacagcgat tggaagctta gctcattaca ttacccatgc cgacagcaaa catttccaac
    51241 caatgaatgt caattttggg atcatcaagg agttggaagg cgagcgtatc cgtgataaga
    51301 aggctcgtta tgaaaaaatt gcagagcgtg cctttgccga cttagaggaa tttttgactg
    51361 tctaattttt ttgaaagaat tgttcatgat actataaaaa tcttagaaat tgtgataaaa
    51421 taggtaggat gaaagaagga gagtgaaaat ggcgaatccc aagtataaac gtattttaat
    51481 caagttatca ggtgaagccc ttgccggtga acgtggcgta gggattgata tccaaacagt
    51541 tcaaacaatc gcaaaagaga ttcaagaagt tcatagctta ggtatcgaaa ttgcccttgt
    51601 tattggtgga ggaaatctct ggcgtggaga acctgcagca gaagcaggta tggaccgtgt
    51661 tcaggcagat tacactggaa tgcttgggac tgttatgaat gctcttgtga tggcagattc
    51721 attgcaacaa gttggggttg atacgcgtgt acaaacagct attgctatgc aacaagtggc
    51781 agagccttat gtccgtggac gtgcccttcg tcaccttgaa aaaggccgta tcgttatctt
    51841 tggtgctgga attggttcac cttacttctc gacagataca acagcggccc ttcgtgcagc
    51901 tgaaatcgaa gcagatgcca tcctcatggc taaaaatggt gtcgatggtg tttacaatgc
    51961 cgatcctaag aaagataaga cagctgttaa gtttgaagaa ttgacccacc gtgacgttat
    52021 caataaaggt cttcgtatca tggactcaac agcttcaacc ctctcaatgg acaacgacat
    52081 tgacttggtt gtcttcaaca tgaaccaatc aggcaacatc aaacgtgtcg tatttggtga
    52141 aaatatcgga acaacagttt caaataatat cgaagaaaag gaataagaaa gaatatggct
    52201 aacgtaatta ttgaaaaagc taaagagaga atgacccaat ctcaccaatc acttgctcgt
    52261 gaatttggtg gtatccgtgc tggtcgtgcc aatgcaagct tgcttgaccg tgtacatgta
    52321 gaatactatg gagtcgaaac tcctcttaac caaatcgctt caattacgat tccagaagcg
    52381 cgtgttttgt tggtaacacc atttgacaag tcttcattga aagacatcga acgtgccttg
    52441 aacgcttctg atcttggtat cacaccggct aatgacggtt ctgtgattcg cttggttatc
    52501 ccagctctta cagaagaaac tcgtcgtgac cttgctaaag aagtgaagaa ggtcggcgaa
    52561 aatgctaaag tggctgtccg caatatccgt cgcgatgcta tggacgaagc taagaaacaa
    52621 gaaaaagcaa aagaaatcac tgaagacgaa ttgaagactc ttgaaaaaga tattcaaaaa
    52681 gtaacagacg atgctgttaa acacatcgac gacatgactg ctaacaaaga gaaagaactt
    52741 ttggaagtct aaaaataaac agaaaaactc agttggcatt gctggctgag ttttattcga
    52801 aagaaggaaa tatgaataca aatcttgcaa gttttatcgt tggactgatc atcgatgaaa
    52861 atgaccgttt ttactttgtg caaaaggatg gtcaaaccta tgctcttgct aaggaagaag
    52921 gtcaacatac agtaggggat acggtcaaag gttttgcata cacggatatg aagcaaaaac
    52981 tccgcctgac aaccttagaa gtgactgcca ctcaggacca atttggttgg ggacgtgtca
    53041 cagaggttcg taaggatttg ggtgtctttg tggatacagg ccttcctgac aaggaaatcg
    53101 ttgtgtcact cgatattctc cctgagctca aggaactctg gcctaagaag ggcgaccaac
    53161 tctacatccg tcttgaagtg gataagaaag accgtatctg gggcctcttg gcttatcaag
    53221 aagacttcca acgtcttgct cgtcctgcct acaacaacat gcagaaccaa aactggccag
    53281 ccattgttta ccgtctcaag ctgtcaggaa cttttgttta cctaccagaa aataatatgc
    53341 ttggttttat tcatcctagc gagcgttacg cagagccacg tttggggcaa gtattagatg
    53401 cgcgcgttat tggtttccgt gaagtggacc gcactctgaa cctctccctc aaaccacgct
    53461 cctttgaaat gttggaaaac gatgctcaga tgattttgac ttatttggaa agtaatggcg
    53521 gtttcatgac cttaaatgat aagtcatctc cagacgacat caaggcaacc tttggcattt
    53581 ctaaaggtca gttcaagaaa gctttaggtg gtcttatgaa ggctggtaaa atcaagcagg
    53641 accagtttgg gacagagttg atttagggag gcttatgaga aaatcatttt acacttggct
    53701 catgaccgag cgcaatccta aaagtaacag tcccaaagca attttggcag acctcgcttt
    53761 tgaagaggca gcttttccaa aacatacaga tgattttgat gaggtcagtc gctttttgga
    53821 ggagcatgcc agtttctctt ttaacctagg agattttgac agcatttggc aggaatatct
    53881 agaacactag catttattca ttgggtttgg gctagtaatt tctccatccc tctgctataa
    53941 taaaaagaaa taaaaggatt agagaggttc tttatttgaa ggaacattca atagacattc
    54001 aactgagtca tccagatgac ctgtttcatc tttttggttc caatgaacgc catcttcgtt
    54061 tgatggaaga agagcttgat gttgtgattc atgctcgtac ggagattgtc caggttttgg
    54121 gagaagagtc tgcctgtgag gaagcccgtc aagttattca ggctttgatg gtcttggtaa
    54181 atcgtgggat gaccgttggt acgccagatg tagtcactgc gattagcatg gtcaaaaatg
    54241 atgaaattga caagtttgtc tccctttacg aagaagaaat catcaaggat aatactggga
    54301 agcctatccg agtcaaaacc ctagggcaaa agctttatgt ggacagtgtc aaacagcatg
    54361 atgtgacctt tggaattggg ccagcaggta cagggaagac cttccttgca gtgaccttgg
    54421 cagtgactgc ccttaaacgt gggcaagtca agcgaattat cctaactcgt ccagcggtgg
    54481 aagcgggaga gagtcttgga tttcttccgg gtgatcttaa ggagaaggtg gatccttacc
    54541 ttcgtcctgt ttacgatgcc ttgtatcaaa ttcttgggaa agaccaaacg actcgtctca
    54601 tggagcgtga aattatcgaa attgcgcccc ttgcctatat gcgtggtcgg accttggatg
    54661 atgcctttgt cattctcgat gaggcgcaaa acacgaccat catgcagatg aagatgttct
    54721 tgacgcgttt aggctttcat tctaagatga ttgtcaatgg agatatcagt cagattgacc
    54781 tgccacgcaa tgtcaagtca ggtttgattg atgcccaaga gaaactcaag aacatccatc
    54841 agattgactt tgttcatttt tcagctaagg atgtagttcg ccatccagtt gtcgctcaaa
    54901 ttatccgagc ctatgaatat tctactgaag ttgcacacga ctgattttga ggaagttcgc
    54961 ctgcaaaaga atatactttt gagagaggaa aatccagttg tataggctaa aggttttatc
    55021 caaaggtctg agacaacgat taggcacgat ggaaagaact tttatgtggc tgatgacgat
    55081 cagtgcatct tcctgtgtca taatcacagg gcacaagaaa gtaggaattt gaaaagatga
    55141 ttgaccaact atctaagtat tacagttgta ggatactaac tgaaaaggat attccaagta
    55201 ttttatcttt atatgaaagt aatcctctgt attttcagca ttgtccacca gagccaaatt
    55261 ttgcaactgt aaaagaggac atgctttgtc tacctgaagg taaagctaag gctgataagt
    55321 tttttgttgg attttggaat ggatctgacc ttgtggctgt tatggatttt gtctatgcat
    55381 atcctgatga ggagactgtt tttattggtt tgtttatggt tgatcaagcc tatcagagga
    55441 aagggattgg tagtcatatt gtgacagaag cactagctta ttttgctaag aactttcgaa
    55501 aggcacgttt ggcttatgtt aagggaaatc cgcaatctca gcatttttgg gaaaagcagg
    55561 gctttaaatc aattggatgc gaggttaagc aagaactcta tacggttgtt atcgctgaac
    55621 agagcctaga agattagaaa tggcatcaag taagaactat ttggaatttg ttttggaaca
    55681 attatcagga ttagatgatg tgacttaccg ttccatgatg ggggagtata ttctttactt
    55741 ccgcggcaag attattggcg gcatttatga cgatcgcttt ttagttaaac ccgtgcaagc
    55801 agtcttagat aagattgacc aatcttcttt tgagtttcca tacaaaggtg ccaaagaaat
    55861 gatttgagtg gaagaacttg ataataagat gtttctataa gacctgattt tagctatgta
    55921 taaccaactg ccaacgccca aacctaaaaa gaaaaaagca agggtgaacg aagtaaaaaa
    55981 gaagtctgct aaggccctgt ctttgcacgg gtaaaatttt atatataaaa agaagctggg
    56041 actaaagagc tcagcttcct ttggtttata taattgtcat tacaagacga agtggttggg
    56101 cgaaactctg ttgactttat tcaatttaga gtttcttatg cacaattgag tctggaacga
    56161 aagtctccag ttgcaaagta tacagtacaa taaaccaacg atgtaatagc tgatgacaca
    56221 aagcacagtg ggtaggactt gtgaagtcac ccttttcttt tcaaaattta tactaaatca
    56281 ttgatatcag tgtagtcacg attaagtcct tgagcaactg gtaggctagt caagtaacct
    56341 tgataagtgg tcacaccttg acgcaagcct tcatcttcag agattgcttg tgcgaatcct
    56401 ttgccagcca aagcttcgat ataaggaaga gtgacattgg ttagggcgat ggttgaagtg
    56461 cgggtaaccg caccagggat attggcaacg gcatagtgga gaacaccgtg tttttcatag
    56521 acgggttcat cgtgcgttgt cacacggtca gctgtttcga taaggccacc ttggtcaaca
    56581 gcaaggtcaa cgatacagag cctggacgca tttgtttgac catctcatct gtcaccaatt
    56641 ccggtgcttt tgcaccaggg atgagaatgg ctccaatcac cacatcagca tctctcacac
    56701 ttgcttcaat gttgaatgaa ttagacataa gagtttgaat ttgacttcca aagacttctt
    56761 ctagaactga gagacgcttg gcactaatat ctaaaatagt cacttgagca ccaagaccaa
    56821 gggcgatgcg ggcagcatgt gtaccgacga caccaccacc gatgatagtt acttttcctt
    56881 ttggaacacc tggtacacca ccaagtagaa caccagagcc accagcttgc ttagtaagga
    56941 agtgagctcc gatttgaaca gccatacgac ctgcaacctc actcatagga acgaggagcg
    57001 gtagttgtcc ttgattgtca cgaacagttt cataggcaat tcctgttgtt tttgctgcta
    57061 acatagcatc tgctaattct ggagcagcgg ccatgtgcaa gtagggaaga gaagaagaac
    57121 gtcgcgcaag taaccgtatt cagaacttaa aggttctttt actttcacaa ccaactctgc
    57181 tgcccaagct tcaccagcag tagcgacaat ctcagctcct tgcttttgat agtcagcatc
    57241 agtaaagcca gaaccgagac cagcatttgt ttcgataagg acacgatgac cacgactaac
    57301 taagctatga acacctgcag gtgtgagggc gacacggttt tcgttatttt taatttcttt
    57361 tgggattccg attaacattg agataaccta cctttcaatt gacggtcttg ttttggttgt
    57421 cacattccag ttcataaatc aaaaatgtga cggtttcatt gtatatgaaa ccgcttcaaa
    57481 aatcaagaaa aacttgtcat ccaaattttt ttatgctaga ctagtgaaaa tcaagctcta
    57541 atggagggaa aagtatggaa tcaatatttg tgaaatttgc ccagtatccg tctatagaaa
    57601 cggagcgttt attgcttaga cctgtaactt tggatgatgc ggaagcaatg tttgactatg
    57661 cctcggacaa gggtaataca cgttacactt ttccaaccaa tcaaagcttg gaagaaacca
    57721 agaataacat tgctcagttc tacttggcta atcccttggg acgttgggga atagaactaa
    57781 aaagcaatgg tcagtttatt ggaaccattg acttacacaa gattgatcct gttcttaaga
    57841 aggtagctat tggttatatt atcaaccaaa cgtattggaa tcaaggatta acgacagaaa
    57901 ccaatcgtgc tgtgattgag ctagcttttg agaagatagg aatgaataag ttagttgctt
    57961 tatacgataa ggctaatccc gcatcaggaa aggtcatgga gaaatcagga atgcgttttt
    58021 cccatgcaga accatatgct tgtatggacc agcatgaaaa aggccgaatc gtgacaagag
    58081 ttcattatgt cttgaccaag gaagactatt ttgcaaataa ataagcagtt gaaaagaaat
    58141 ttttcgactg ttttttcttc ctcttacgaa taatctaaga gaggagaaaa tatggaagca
    58201 attatcgaga aaatcaaaga gtataaaatc atcgtcatct gtactggtct gggcttgctt
    58261 gtaggcggat ttttcctgct aaagccagct ccacaaacac ctgtaaagga aacgaatttg
    58321 caggctgaag ttgcagctgt ttccaaggat ttggtatccg aaaaggaagt gaacaaggaa
    58381 gagaaggaag aaccagttga acaagatcta atcacagtag atgtcaaagg tgctgtcaaa
    58441 tcgccaggga tttatgactt gcctgtaggt agtcgagtca atgatgctgt tcagaaggct
    58501 ggtggcttga cagagcaagc agacagcaag tcgctcaatc tagctcagaa agttagtgat
    58561 gaggctctgg tttacgttcc tactaaggga gaagaagcag ttagtcaaca gactggttcg
    58621 gggacagctt cttcaataag caaggaaaag aaggtcaatc tcaacaaggc cagtctggaa
    58681 gaactcaagc aggtcaaggg actgggagga aaacgagctc aggacattat cgaccatcgt
    58741 gaggcaaatg gcaagttcaa gtcagtagac gagctcaaga aggtctctgg cattggtggc
    58801 aaaacaatag aaaagcttaa agactatgtt acagtggatt aagaatttct ctattcccct
    58861 aatttacctg agttttctat tactttggct ttattacgct attttctcag catcttatct
    58921 tgctttgttg ggctttgttt ttctgctagt ctgtctcttt atccaatttc cgtggaaatc
    58981 tgctggtaaa gttctaataa tttgcggaat ctttggattt tggtttgttt ttcaaaattg
    59041 gcaacagagt caagcgagtc aaaatctggc ggattctgtt gaaagggtac ggattttgcc
    59101 tgatactatt aaggttaatg gtgatagtct atcctttcgt ggcaagtcta acggtcgtgc
    59161 tttccaagtc tattataaac tccagtccga ggaggagaaa gaagcctttc aagctttaac
    59221 cgacctgcat gagataggac tagaagggaa gctttcggag ccagaagggc agagaaattt
    59281 tggtggcttt aattaccaag cctatctgaa gactcaggga atttaccaga ctctcaatat
    59341 caaaacaatc cagtcacttc aaaagattgg cagttgggat ataggagaaa acttgtccag
    59401 tttacgtcga aaggctgtgg tttggattaa gacgcacttt ccagacccta tgcgcaatta
    59461 catgacagga ctcttgctgg gacatctgga caccgacttt gaggagatga atgagcttta
    59521 ttccagtcta ggaattatcc acctctttgc cctatctggc atgcaggtag gttttttcat
    59581 gaatggattt aagaaacttc tcttgcgatt gggcttgacc caagaaaagt tgaaatggct
    59641 gacttatccc ttttccctta tctatgcggg actaactgga ttttcagcat cggttattcg
    59701 cagtctcttg caaaagctac tggctcaaca tggggttaag ggcttggata attttgcctt
    59761 gacagtgttt ctcctcttta ttgtcatgcc aaactttttc ttgacagcag gaggagtctt
    59821 gtcctgcgct tatgctttta tcctgaccat gaccagcaaa gaaggggagg ggctcaaggc
    59881 tgttgctagt gaaagtctag tcatctcctt gggcatattg cccattctat ccttctattt
    59941 tgcggaattt caaccttggt ctatcctttt gacctttgtc ttttcctttc tatttgactt
    60001 gaccttctta ccgctcttgt ctatcttatt tgtcctttcc tttctctatc cagtcattca
    60061 gctgaacttt atctttgaat ggttggaggg cattattcgc ttggtctcac aggtggcaag
    60121 taggcctcta gtctttggac aacccaatga atggctttta atcctattgt taatttcttt
    60181 gcctttggtc tatgatttga ggaaaaacat taaaggatta acagtattga gtttattgat
    60241 tacaggtctc tttttcctta ccaagcatcc actggaaaat gaaatcacca tgctggatgt
    60301 ggggcaagga gaaagtattt tcctacggga tgtaactggg aaaaccattc tcatagatgt
    60361 aggtggtaag gcagaatctt ataagaaaat caaaaaatgg caagaaaaga tgacgaccag
    60421 caatgcccag cgaaccttga ttccctatct caaaagtcgg ggagtagcta agattgacca
    60481 gctaattttg actaacacgg acaaggagca tgttggagat ttgtcagaga tgaccaaggc
    60541 tttccatgta ggggagattc tagtatcaaa agacagtctg aaacagaagg aatttgtggc
    60601 agaattacag gcgactcaaa caaaggtgcg tagtatgata gtaggggaga acttgcccat
    60661 ttttggaagt cagttagaag ttctatctcc aaggaaaatg ggagatggag gacacgatga
    60721 taccctagtt ctgtatggga aattcttgga taagcaattt ctcttcacgg gaaatttgga
    60781 ggagaaagga gagaaggact tgctgaagca ctatccagac ttgaaagtaa atgttttgaa
    60841 agctagccaa catggcaata aaaaatcatc aagtccagcc tttctagaaa aactcaaacc
    60901 agagcttact cttatctcag ttggaaagag caatcgaatg aaactccccc atcaggaaac
    60961 attgacacga ctggaaggta tcaatagcaa agtttatcga actgaccagc aaggagctat
    61021 acgttttaag gggttggata gttggaaaat cgaaagtgtt cgataggaag gataaatgtt
    61081 gtagattagt gaaataaact aaaaatttgt tgcataataa tgataaaaat ggtataatga
    61141 aaacgtattc aatattgagt atataaaatc attaaaaatt agcaaaagtt gttttattag
    61201 ttagtttata atctattggt cttcttcagt ccagtgtatc tgctgtgaca gccactaaaa
    61261 gttacaagta tgattggaat acggttttgg aatatagtac caactatcac gaccatcagt
    61321 atgcttggat tccggaatgg tctcgttatt acagctattc tgagtataaa gttggcggag
    61381 gctggaacta cgctcgttat gaggtcataa actactatac tggaggttat taatccttaa
    61441 agagtgagaa aaggagggct ggatatgtta aatcttactc atgttacctt aaaaacgcga
    61501 caagtcatct tgcaagatgc ggattttacc tttaaaaagg gtaggattta tggccttctt
    61561 gctatcaatg gctcgggaaa gacgacacta ttccgagcta tgagcaagtt gcttcccctt
    61621 agtagtggac acatcgcagt tcctccttct ttgttttatt atgagagcgt tgaatggctg
    61681 gatggaaact taagtgggat ggactacctt cgtctcataa aaaacatctg gaagtcagac
    61741 ctaaacttga gagatgaaat cgcctactgg gaaatggctg actatatcag tcttcccatc
    61801 cgcaagtatt ccttaggcat gaagcaacgc ttggtgattg ctatgtattt tctcagtcag
    61861 gccaaatgct ggctcatgga tgagattaca aatggcttag acgagtatta tcgacagaag
    61921 ttttttgata ggctagcaca aatcgataga caagaacagc tggttctttt aagttcccac
    61981 tataaggaag agttggttga tatctgcgat agagtagtaa ccattcatca ggggcagata
    62041 gaagaggttt agtttatgaa agatgttagt ctatttttat tgaaaaaagt tttcaaaagt
    62101 cgtttaaact ggattatctt acttttattt gcatctgtac tcggtgttac cttttattta
    62161 aatagtcaga ctgcaaactc acacagcttg gagagcaggt tggaaagtcg cattgcagcc
    62221 aacgagaggg ctatcaatga aaatgaagag aaactctccc aaatgtctga taccagctcg
    62281 gaggaatacc agtttgctaa aaataattta gacgtgcaaa aaaatctttt gacgcgaaag
    62341 acagaaattc taactttact aaaagaaggg cgctggaaag aagcctacta tctgcagtgg
    62401 caagatgaag agaagaatta tgaatttgta tcaaatgacc cgactgctag ctctggctta
    62461 aaaatggggg ttgaccgcga acggaagatt taccaagccc tgtatccctt gaacataaaa
    62521 gcacatactt tggagtttcc gacccacggg attgatcaga ttgtctggat tttagaggtt
    62581 atcatcccaa gcttgtttgt ggttgcgatt atttttatgc taacacaact atttgcagaa
    62641 agatatcaaa atcatctgga cacagctcac ttatatcctg tttcaaaagt gacatttgca
    62701 atatcctctc ttggagttgg agtgggatat gtaactgtgc tgtttatcgg aatctgtggc
    62761 ttttcttttc tagtgggaag tctgataagt ggttttggac agttagatta tccctaccca
    62821 atttatagct tagtgaatca agaagtaact attgggaaaa tacaagatgt attatttcct
    62881 ggcttgctct tagctttctt agcctttatc gtcattgtgg aagttgtgta cttgattgct
    62941 tactttttca agcaaaaaat gcctgtcctc tttctttcac tcattgggat tgttggctta
    63001 ttgtttggca tccaaacaat tcagcctctt caaaggattg cacatctgat tccctttact
    63061 tacttgcgtt cagtggagat tttatctgga agattatcta agcagattga taatgtcgat
    63121 ctaaattgga gcatggggat ggtcttactt ccttgcctga ttatcctttt gttagtgggg
    63181 attctattta tcgaaagatg gggaagttca cgtaaaaagg aagtttttaa agtttagttt
    63241 tcctataggg aagctaaaga aaaactaaca tagggagaga atcaacttgg ttctctcttt
    63301 ttgattcgaa aaccaaacca aaatacaaa
//
LOCUS       DAVLTT010000006        62764 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLTT010000006 DAVLTT010000000
VERSION     DAVLTT010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62764
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.006"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            291..1142
                     /locus_tag="VYN15_000392"
     CDS             291..1142
                     /locus_tag="VYN15_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1451768.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYIWNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLSEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKVFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVEILEKE
                     INDFSNL"
     gene            complement(1364..1714)
                     /locus_tag="VYN15_000393"
                     /pseudo
     CDS             complement(1364..1714)
                     /locus_tag="VYN15_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1854..2189)
                     /locus_tag="VYN15_000394"
     CDS             complement(1854..2189)
                     /locus_tag="VYN15_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451769.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(2280..3590)
                     /gene="der"
                     /locus_tag="VYN15_000395"
     CDS             complement(2280..3590)
                     /gene="der"
                     /locus_tag="VYN15_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV1451770.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(3604..4317)
                     /locus_tag="VYN15_000396"
     CDS             complement(3604..4317)
                     /locus_tag="VYN15_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV1451771.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(4314..5210)
                     /gene="dnaI"
                     /locus_tag="VYN15_000397"
     CDS             complement(4314..5210)
                     /gene="dnaI"
                     /locus_tag="VYN15_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV1451772.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(5211..6380)
                     /locus_tag="VYN15_000398"
     CDS             complement(5211..6380)
                     /locus_tag="VYN15_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV1451773.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLVLHAPLSSQD
                     FLEHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     EQKAKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            complement(6381..6854)
                     /gene="nrdR"
                     /locus_tag="VYN15_000399"
     CDS             complement(6381..6854)
                     /gene="nrdR"
                     /locus_tag="VYN15_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV1451774.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            6994..7359
                     /locus_tag="VYN15_000400"
     CDS             6994..7359
                     /locus_tag="VYN15_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1451775.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            7364..8059
                     /locus_tag="VYN15_000401"
     CDS             7364..8059
                     /locus_tag="VYN15_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451776.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDTEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            8076..8843
                     /locus_tag="VYN15_000402"
     CDS             8076..8843
                     /locus_tag="VYN15_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451777.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(9196..10395)
                     /locus_tag="VYN15_000403"
     CDS             complement(9196..10395)
                     /locus_tag="VYN15_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1451778.1"
                     /translation="MRNMWVVIKETYLRHVKSWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILVHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMASRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(10392..11285)
                     /locus_tag="VYN15_000404"
     CDS             complement(10392..11285)
                     /locus_tag="VYN15_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451779.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPIQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            11402..11482
                     /locus_tag="VYN15_000405"
                     /pseudo
     CDS             11402..11482
                     /locus_tag="VYN15_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            11992..12180
                     /locus_tag="VYN15_000406"
                     /pseudo
     CDS             11992..12180
                     /locus_tag="VYN15_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            12595..13212
                     /locus_tag="VYN15_000407"
     CDS             12595..13212
                     /locus_tag="VYN15_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV1451780.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(13532..14419)
                     /locus_tag="VYN15_000408"
     CDS             complement(13532..14419)
                     /locus_tag="VYN15_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1451781.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(14568..16451)
                     /locus_tag="VYN15_000409"
     CDS             complement(14568..16451)
                     /locus_tag="VYN15_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1451782.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            16828..18282
                     /locus_tag="VYN15_000410"
     CDS             16828..18282
                     /locus_tag="VYN15_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1451783.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            18263..19228
                     /locus_tag="VYN15_000411"
     CDS             18263..19228
                     /locus_tag="VYN15_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1451784.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(19263..20537)
                     /locus_tag="VYN15_000412"
     CDS             complement(19263..20537)
                     /locus_tag="VYN15_000412"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV1451785.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKYQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(20537..21709)
                     /locus_tag="VYN15_000413"
     CDS             complement(20537..21709)
                     /locus_tag="VYN15_000413"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV1451786.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(21840..22088)
                     /locus_tag="VYN15_000414"
     CDS             complement(21840..22088)
                     /locus_tag="VYN15_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451787.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(22156..22780)
                     /locus_tag="VYN15_000415"
                     /pseudo
     CDS             complement(22156..22780)
                     /locus_tag="VYN15_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(22842..23291)
                     /locus_tag="VYN15_000416"
     CDS             complement(22842..23291)
                     /locus_tag="VYN15_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1451788.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(23293..24051)
                     /locus_tag="VYN15_000417"
     CDS             complement(23293..24051)
                     /locus_tag="VYN15_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1451789.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(24166..26145)
                     /gene="pknB"
                     /locus_tag="VYN15_000418"
     CDS             complement(24166..26145)
                     /gene="pknB"
                     /locus_tag="VYN15_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV1451790.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIILTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(26142..26882)
                     /locus_tag="VYN15_000419"
     CDS             complement(26142..26882)
                     /locus_tag="VYN15_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV1451791.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(26897..28210)
                     /gene="rsmB"
                     /locus_tag="VYN15_000420"
     CDS             complement(26897..28210)
                     /gene="rsmB"
                     /locus_tag="VYN15_000420"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV1451792.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(28203..29138)
                     /locus_tag="VYN15_000421"
     CDS             complement(28203..29138)
                     /locus_tag="VYN15_000421"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV1451793.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGCDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPKEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(29151..31547)
                     /locus_tag="VYN15_000422"
     CDS             complement(29151..31547)
                     /locus_tag="VYN15_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV1451794.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEELVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(31613..31927)
                     /locus_tag="VYN15_000423"
     CDS             complement(31613..31927)
                     /locus_tag="VYN15_000423"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV1451795.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(31952..32578)
                     /gene="gmk"
                     /locus_tag="VYN15_000424"
     CDS             complement(31952..32578)
                     /gene="gmk"
                     /locus_tag="VYN15_000424"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV1451796.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(32708..34321)
                     /locus_tag="VYN15_000425"
     CDS             complement(32708..34321)
                     /locus_tag="VYN15_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV1451797.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(34590..34820)
                     /locus_tag="VYN15_000426"
     CDS             complement(34590..34820)
                     /locus_tag="VYN15_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV1451798.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            complement(35058..36155)
                     /locus_tag="VYN15_000427"
     CDS             complement(35058..36155)
                     /locus_tag="VYN15_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV1451799.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQSMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARENVLPEVIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNPSIAEQNFGRVPIRIETN"
     gene            complement(36165..36911)
                     /locus_tag="VYN15_000428"
     CDS             complement(36165..36911)
                     /locus_tag="VYN15_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1451800.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(37014..37367)
                     /gene="rsfS"
                     /locus_tag="VYN15_000429"
     CDS             complement(37014..37367)
                     /gene="rsfS"
                     /locus_tag="VYN15_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV1451801.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(37380..37880)
                     /locus_tag="VYN15_000430"
     CDS             complement(37380..37880)
                     /locus_tag="VYN15_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1451802.1"
                     /translation="MKMAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(37881..38474)
                     /gene="yqeK"
                     /locus_tag="VYN15_000431"
     CDS             complement(37881..38474)
                     /gene="yqeK"
                     /locus_tag="VYN15_000431"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV1451803.1"
                     /translation="MSYQDYINCSREALLEKMVEFLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVVYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(38474..39103)
                     /locus_tag="VYN15_000432"
     CDS             complement(38474..39103)
                     /locus_tag="VYN15_000432"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV1451804.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(39155..39466)
                     /gene="yhbY"
                     /locus_tag="VYN15_000433"
     CDS             complement(39155..39466)
                     /gene="yhbY"
                     /locus_tag="VYN15_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV1451805.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(39680..40786)
                     /gene="yqeH"
                     /locus_tag="VYN15_000434"
     CDS             complement(39680..40786)
                     /gene="yqeH"
                     /locus_tag="VYN15_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV1451806.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSNALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAREEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            complement(40789..41379)
                     /locus_tag="VYN15_000435"
     CDS             complement(40789..41379)
                     /locus_tag="VYN15_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV1451807.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(41331..42239)
                     /locus_tag="VYN15_000436"
     CDS             complement(41331..42239)
                     /locus_tag="VYN15_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1451808.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESETVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFV
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(42296..42856)
                     /locus_tag="VYN15_000437"
     CDS             complement(42296..42856)
                     /locus_tag="VYN15_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV1451809.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            42995..44213
                     /gene="sstT"
                     /locus_tag="VYN15_000438"
                     /pseudo
     CDS             42995..44213
                     /gene="sstT"
                     /locus_tag="VYN15_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            44281..45234
                     /locus_tag="VYN15_000439"
     CDS             44281..45234
                     /locus_tag="VYN15_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1451810.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(45425..45649)
                     /locus_tag="VYN15_000440"
     CDS             complement(45425..45649)
                     /locus_tag="VYN15_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HEV1451811.1"
                     /translation="MIEILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLIFMVITYK"
     gene            complement(45654..45833)
                     /gene="asp4"
                     /locus_tag="VYN15_000441"
     CDS             complement(45654..45833)
                     /gene="asp4"
                     /locus_tag="VYN15_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HEV1451812.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(45835..47172)
                     /gene="gtfB"
                     /locus_tag="VYN15_000442"
     CDS             complement(45835..47172)
                     /gene="gtfB"
                     /locus_tag="VYN15_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HEV1451813.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIAGALPAVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQETMQTVLGG"
     gene            complement(47165..48676)
                     /gene="gtfA"
                     /locus_tag="VYN15_000443"
     CDS             complement(47165..48676)
                     /gene="gtfA"
                     /locus_tag="VYN15_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HEV1451814.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDEDKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(48688..51060)
                     /gene="secA2"
                     /locus_tag="VYN15_000444"
     CDS             complement(48688..51060)
                     /gene="secA2"
                     /locus_tag="VYN15_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HEV1451815.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLLDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKEYHAKGNPLLVFVGSVEMSQLYSSLLL
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDMIYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWIEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(51053..51493)
                     /gene="asp3"
                     /locus_tag="VYN15_000445"
     CDS             complement(51053..51493)
                     /gene="asp3"
                     /locus_tag="VYN15_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HEV1451816.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYLDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(51490..53025)
                     /gene="asp2"
                     /locus_tag="VYN15_000446"
     CDS             complement(51490..53025)
                     /gene="asp2"
                     /locus_tag="VYN15_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HEV1451817.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKALREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(53009..54589)
                     /gene="asp1"
                     /locus_tag="VYN15_000447"
     CDS             complement(53009..54589)
                     /gene="asp1"
                     /locus_tag="VYN15_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HEV1451818.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEPNGQIHMHHIMDDRGFVSSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNVVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLADVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(54599..55816)
                     /gene="secY2"
                     /locus_tag="VYN15_000448"
     CDS             complement(54599..55816)
                     /gene="secY2"
                     /locus_tag="VYN15_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HEV1451819.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYFYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNDTYRPLI"
     gene            complement(55873..56550)
                     /locus_tag="VYN15_000449"
     CDS             complement(55873..56550)
                     /locus_tag="VYN15_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1451820.1"
                     /translation="MGISVAKGEYITIVDSDDIVKENMIETLYQQVQEKDADVVIGNY
                     YNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFNSSAFILPTFKLIKKELFN
                     EVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSGSIMRTEFDLSWARDIVE
                     VFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLTDTEEYKDICFRLKLFFDA
                     EQRNGKS"
     gene            complement(56535..56777)
                     /locus_tag="VYN15_000450"
     CDS             complement(56535..56777)
                     /locus_tag="VYN15_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1451821.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGQHKLKIWGLV"
     gene            complement(56777..57973)
                     /locus_tag="VYN15_000451"
     CDS             complement(56777..57973)
                     /locus_tag="VYN15_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV1451822.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNSGVLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMAGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            complement(57982..59202)
                     /locus_tag="VYN15_000452"
     CDS             complement(57982..59202)
                     /locus_tag="VYN15_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HEV1451823.1"
                     /translation="MRNTKRAVVFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(59233..61677)
                     /locus_tag="VYN15_000453"
     CDS             complement(59233..61677)
                     /locus_tag="VYN15_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HEV1451824.1"
                     /translation="MNKTIVLAGDRNYTRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYARYFIADYIQEDTVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNAGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELGRAYNLQVGHDIVALYNNWQEHLAF
                     NDKPVVIHFTTYRKPWTTLTANRYRDLWWEFHDLEWSQILQHHMGEFELISPLDKEFS
                     CLTLTNSQDLEGIEELVTALPDVVFHIAAWTNMGDKLIKLAVYDNVRLHPQIVPPVLD
                     KLERSVDLYLDINYSHVVGTILEDMKILEKPILSFDTTEHGNTGQLVFKKDEVSVMVQ
                     AIKDYRRDGRFLSCYEGSDFHCLTFTNSQELQKIDYLVKNFTMVTFHIAAWTVMGPML
                     QELAKKYKNVKLYPEVKSDQFEELKSQMDVYLDINLHNSTSEVVKEISSLNKPMLAFY
                     TSQNGNHGQHLYSSEHPERLLQAFHALIKGETLGEPEKPIKVIGIDQTLDYVIKNKSS
                     LVRFGDGEVNLMWGLPIPYQNHDLELANQLKHIVGLESDEKLVVCLPDAFDDRFVFTW
                     WATPFWKEHMNVYMDFYKELCKGSWYGSTFISRPYIDYEDKSKAKGQFEKLKSIWENR
                     DILIVEGITSRSGVGNDLFNKVKSVKRIICPSHNAYSVVDNIQEEIMKHAEGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEHNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            complement(61687..62697)
                     /locus_tag="VYN15_000454"
     CDS             complement(61687..62697)
                     /locus_tag="VYN15_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1451825.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYLYMYNLSDILIVPSEQMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWFQDTPLRVFSNKGEASSNARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTHQNDGESNQYYTLNISHKVSTYLTAGIPVIVPSNLSTAKFIV
                     DQGLGFMANSLEEVHEIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     ID"
BASE COUNT        18453 a        13990 c        11351 g        18970 t
ORIGIN      
        1 tctcctcctt acctataagc tataaaatat ttaagtttgg ctataataaa actacaaaaa
       61 ataagtatgt caaacttaac taaagaatat aaataacaca tcaattagtc actcccaaaa
      121 ccatatatca aaccatggta ttaaaggctc ccaatcatta caatatataa caaaattaag
      181 tgaatcttct atttccatga cttttccctc ctttttgata taataatacc acctttttct
      241 acgtttttta taaatgtaga aaatattcac atttacctag gaggaacaat atgagatggg
      301 attatggaca gatttttaaa gaaattcgaa agtcaaaagg attgacccaa caagatgtat
      361 gtggacaagt catacatcgg acaactctaa caaatattga acacggtaaa gttattccca
      421 gttttgaaaa catggtattt cttcttgaac aaattgatat gagcttggca gaattcaagt
      481 atatatggaa cgaataccat cctagtaaaa ggcgagatat tattgtagag agccaaaatc
      541 cgtctacttt tcaagatact agaaaaatgg ttgaactcac tgagaaatgt caaaaatatc
      601 ttaagacaca tcacgatgtt cctattcaaa atatctatcg tcatacaaaa attgtcacag
      661 agttacgaac taaaggattc aaaaacaacc acgtcttgaa agatttgtct gaagaaattt
      721 gggactatct tgaacctatg gatacatggt acattagtga tttgaaattg cttggaacca
      781 ttctcttttt ctttccttct gaaaatcttc cccttcttat tgatagaatt atgaaaacca
      841 tcgagaaata taaatacttc cgagaaacaa aagtattttt atcatctttt ttagccaatc
      901 tctccactgt atattttcaa catcatttat tcaaagaatg tgaaacaatc accctacaac
      961 ttttggtatt agcagaagaa ttaaaaatat acgatattct tggattctct caagtacgct
     1021 tgggaatact acaacataac tccgatttga ttgataaagg aataacttta ttacgactaa
     1081 ccaaagaaga ggcattagtt gaaatactcg aaaaagaaat taatgatttt tcaaacctat
     1141 aatttgtaat aactctcatc attttattat agtagattgt aatagaatgt gaacgaatca
     1201 attaggggat ctaaagcatt ttataccaat gttttataag ttgtattgta ttattccata
     1261 ttcaatccac tatacaagat gaatatttct ctcaagtttc ataatcaaaa taaaaatgac
     1321 tgtatctata gctccataaa aaaatcatag atacagtcat tttttagttc ctacaccttc
     1381 ctttatgcac acctttagac ttccctagtt cccgtctcaa gtcaagcatt tttttgaaac
     1441 agatatagtc taaccagtca ctagcaaaag cgataagtag taataatagc caaatacctc
     1501 ataacttgat atctgtcaaa tttctcaaga cgatattgaa aaacagaact gaaaaaactg
     1561 tccaagcaag gctaaaaaga gcatagaggg tgatgtaaat ccagtaaaaa tagtaaaaaa
     1621 ttgggaaaaa tttactttct ctattatcct tgtcaatcca gctgaaaaag taaaaacagg
     1681 gtaataagat tatcatttta aacaagtgtt ccatcacaag cctccttttt taaattgttt
     1741 tctttagttt cgttctatta aatgttatta ccaatataaa ccttggaata gcgtgtaata
     1801 aatgatttta gaggtaccat aagccacctc ctacaaatag aaaccgatat aaatcaatgc
     1861 cttccaccct tagacttccc tagttcctgt ctcaagcgaa acatttcttt gaaacaggaa
     1921 taagttaacc aattcatacc aatagctagc agaataaaaa gaaaccaaat gccccataac
     1981 ttgatatctg tcacatttct caagacggta ttgaaaaaca gaactgaaac aactgtccaa
     2041 gcaaggctaa aaagagaata gaaggggatg taaaaccagt aaaaataata aaaaattgga
     2101 aaaaacttac tatttctgtt ggccttctca atccagttat caaaataaaa gtacggtgct
     2161 aaaagtaaga atttaaacaa atgttccatc accgacatca ccctccttct tttgatagcg
     2221 ttttctatta ttttattata tcaaaaaaat ccggaactgt cattccagat tctacttttt
     2281 tatttgcgtt ttcttgcgat gagatgaatc ggtgttccct caaaaacaaa ggccttgcgg
     2341 atttgatttt ccaagaaacg caggtaagaa aagtgcatga gttcttcttc attgacaaag
     2401 atgacaaagg ttggtggttt ggttgccact tgggtcgcat agaaaatctt gagacgtttt
     2461 cctttgtctg tcggtgttgg gttgatggca atggcatcca tgatgacatc gttcaagaca
     2521 gctgatggaa tacgtgtatt ttgactttcg ctgatttgct taatcatctc aggaagtttg
     2581 tggagacgtt gcttggttaa agctgataca aagataatcg gtgcgtaagg caggtattgg
     2641 aactgctcac ggatatcttc ttcccagttt ttcatagtgt ggttatcttt ttcaagcgta
     2701 tcccacttgt tgaccacgat aatcatccct ttaccagctt catgggcaaa tcctgcgata
     2761 cgcttgtcgt actcacgaat gccttcttcc gcattgatga ccatcaagac cacatctgaa
     2821 cggtcaatag cacgcatggc acgcataaca gagtatttct cagtattttc ataaacctta
     2881 ccagacttac gcataccagc cgtatcaatc atggtaaact cttgaccatc tgtatctgta
     2941 aagtgggtat caatggcatc acgagttgtt ccagcaacag gactagcaat aacacggtct
     3001 tctcccaaga tagcattgat caagcttgat tttccaacgt taggacgacc aatcaagcta
     3061 aacttaatga catctggatt ttcttcctca tattcatttg gaagattttc tacgatcgca
     3121 tctagcacat cccctgtacc gattccatgg acagatgaga taggcaatgg ttcacccaaa
     3181 ccgagagcat agaaatcata gatatcattt ctcatctcag ggttgtccac cttgttgact
     3241 gcgaggataa ctggtttgtg ggtcttataa agcttacgag ctacgtattc gtctgcatca
     3301 gtaattcctt ccttaccaga cacgacaaaa acgataacat ctgcttcttc catggcaatt
     3361 tctgcctggt gcttgatttg ttccatgaaa ggagcatcga catcatcaat tcctcctgta
     3421 tcaatcatgc taaaagaacg attgagccac tcacccgttg cataaatacg gtcacgtgtc
     3481 actccttcga catcttctac aatggagatt cgctcaccag cgatccgatt aaatagggtt
     3541 gatttcccaa cattgggacg tcctacaatg gcaatagttg gtagggccat aatttctcac
     3601 tttctacaat aatttcttct gttcaagatt ttttctagtt gagcttggtt cagcttgacc
     3661 aaactgttct gctaggcgct gactccagct tgtggtcgca cgcgccccag catagtcagc
     3721 ctgaacacgg tcataagctt ggattgcctc agttgactgt tcttggtatt cttcctcaaa
     3781 gacaacattc tctagtggca gtcttggttt catatcatga tgttgatttg gcacacccag
     3841 tgccatccca aagacagaat aggtgtagtc aggtaggtta aagagctctg ccacttcttc
     3901 agacttgtat cgaaccaaac cgataatcac accaccatag cccaagcttt cagctgccaa
     3961 caaggcgttt tgtccagcaa gagctgcatc gaccgaacta atcaagagac cttccacacc
     4021 ttggggttgg aaggtgtcgg tatgaagtcg ggctcccttt tctgctcggt tcaaatctcc
     4081 gacaaagaga aggaaaacag cagactggcg aatggcttct tgaggtacca attcatacaa
     4141 ggcatctttc ttctcttgac ttcgtaccac aatcacagag taggattgga aattcttcca
     4201 agatgatgcc atctgggctg ctgtcaaaat ctcatttaag tctacttggg gaatttcttg
     4261 ctctttaaac ctgcgcactg aagtatgagc cttcatcaat ttaatggttt ctgtcatcga
     4321 cggtttactc cttctaaacg agtctcctca gccaaataac ggatgcgttc catgacccgt
     4381 ctggcttccc aggtttcgtc atttccatgt ttcactttcg caaaatgctt ctccaaatct
     4441 tcaaagttga agttggatgt gaaaaaggtc ggtaaatttt cctgcatccg atattggaga
     4501 atgacctgca ggatttcgtc acgcacccaa acggttgatt gctcggcgcc aatatcatct
     4561 aaaatcagga cctcagacag cttaatctca tccaccaagg tcttaacatt gccatcactg
     4621 atagcatttt tgacatcaat gacaaagcta ggatagtgga ggagagtgga tgatacacca
     4681 cgtttttctg ataaatcatg agctagggca gccaccatga aacttttacc cacaccaaag
     4741 tctccataca agtaaagacc tttcaaatta ttggggtaat cgttaacaaa ttctatcatt
     4801 ctttttagaa cagttaagcg ctgaacatca tcacgataaa catctaaaaa actgacattt
     4861 ttcaggctag atggaaaatt aattaagttg agacgtttct tgatagccgc ttctttttca
     4921 gctgcgatta gttcaggagt ttcttcataa gaaacatctg catagccatg gttcatgact
     4981 aatataggct tgtagccttt ggcaatataa tctgtatctc ctcggaggaa tttatctctc
     5041 tcagtgatgt attggttaaa cttggaaata ctacggttca actcgtcctg attgagggat
     5101 tcttgctgga caaaggccgc aacatcagga tccttcatga ttttctgaac taaatcttga
     5161 tagtgaaaac gacttggttg acgtttgagt acatctccga cactttccat ctaatcacct
     5221 ccgttatcta attttgctaa taattctagg gtttggcgtt ccatctcttc taattcctca
     5281 gcggatgacg tatttttata ttcaggatta ctccatttag gaatattggt ttttgctggg
     5341 gcagtctgat tctgtttttg tgtttttgct ttctgttctc gctcacggat gcgcaagact
     5401 gccttttctg ccgaatgaat cttttgatag gcatagtcat tggctacctt catggcatat
     5461 ttctcattga tatttgccga atcgacctta ttaaaggtca ataaaagaat gatattgatg
     5521 acttcgtcca gcaagcccaa gccagccatc tgttgcaaga gttctctttc tgtttgggta
     5581 atggttccct tgcgtgtttg cttgatttct gccaagaact gcagggcagt tttacttttg
     5641 gcttctttga taatggttgt ttccttaaga ctaaagtcag aggaaactgg tttttgagca
     5701 attttttccc gcatgcgttt ggttgaaata acctgagaaa cagctgttga cttggccaat
     5761 tgataggttt caaaccaagt ccatttcttc tcctcggcaa tagcaaagag gtttaagaca
     5821 tcggactgct catccgcaaa acgaagtcca tctcgagcca tcagctggcg aaaatggtcc
     5881 aagtcaaaat cgttggccac tttcttcttg agaccaaggt cttcttgact gcctagttct
     5941 gccaattctg gaaagacttg attgagtgag acaggtattt cttcaccatc agcactttca
     6001 actttcaaat cctccacagc tacatcgcca atctttttct ctaagagtct gcgataaaca
     6061 ggatgctcca agaagtcttg actagataga ggagcatgga ggactagctg ataaacatcc
     6121 cccttttgat agagggtcaa gagattaaaa gcagataaga ttttcaatga ttttatcagt
     6181 ctatccatcc caaagttaag atggttgaga atgcttgaaa aaagatattc ctttctacca
     6241 ttatcccaaa aactgattgt ataaagataa aggctcagtg cctcctgacc gataatcggg
     6301 aggtagcact gtaccagaga tgaggtatct tgcgacaccc gattattctt tagataagaa
     6361 aaacggtcaa ttggcttcat ttatctttcc tttttctttt tagaggactg ggtgatttgt
     6421 tggagcaagc tctctaactc actgacatcc ttaaaactac gatagacact agcaaaacgt
     6481 acataggtaa tctcgtccaa ttcagccaac tcctccatga cgagtgaacc aatgtcctca
     6541 ctttgaattt cattttcatt tcgaccacgg agtttctgtt cgatacgatt gactaccatg
     6601 ttgatttcat cacttgacac aggacgtttc tgggctgagc ggataatccc attaaagatt
     6661 ttatctctgg agaattgttc ccgtgtgcca tcttttttaa caaccactaa ggttctttct
     6721 tctactcgtt cgtaggttgt aaaacggtgt tggcattcgt cgcactcacg tcttctacga
     6781 atggtgttcc cttcttctgc ttggcgacta tcgataacac ttgacttggt agccccacat
     6841 tttggacaac gcatcctttc cctccttatc gttttctttt cattatacca ttttttaagc
     6901 gattcccaaa acaattcttc tttttgcttg acaagttttt tgttttgttg tattatttaa
     6961 ttaagacaaa aaggtaaaag aaaggagact aagatgtcct ggacatttga caacaaaaaa
     7021 cccatctatt tacagattat ggagaaaatc aagcttcaga ttgtttccca tacactggaa
     7081 cccaatcaac aacttccaac cgtgagggag ctagctagcg aggctggtgt caatcccaat
     7141 accatccaaa gagccttatc agaccttgaa cgagaaggat ttgtctacag caagcgaaca
     7201 actggacgat ttgtgactaa ggataaggag ctaatcgctc agtcacgcaa acaattatca
     7261 gaagaagaat tggaacactt cgtttcctcc atgacccatt ttggctatga aaaagaagaa
     7321 ctaccaggcg tagtcagtga ttatattaaa ggagtttaag cctatgtcat tactagcatt
     7381 tgaaaatgta tccaaatcat atggagcaac accagccctt gaaaatgttt ctcttgacat
     7441 tccagctgga aaaattgtcg gccttcttgg gccaaacggc tcaggaaaaa caaccctgat
     7501 taaactaatt aatggcctct tacaaccaga tcaaggacgt gtcctcatca acgacatgga
     7561 cccaagccca gcaaccaagg ccgttgtagc ttatttgcct gatacgacct atctcaatga
     7621 gcaaatgaag gtcaaagaag ccctaaccta cttcaagacc ttctataaag atttcaatct
     7681 tgaacgcgcc catcatctac ttgcagacct gggcattgat gaaaatagtc gtctcaagaa
     7741 actatcaaaa ggaaacaaag aaaaggttca actgattttg gttatgagcc gtgatgctcg
     7801 tctctatgtt ttggatgaac ccattggtgg ggtggatcca gcagcccgtg cttatatcct
     7861 caataccatt atcaacaact actcaccaac ttctaccgtt ttgatttcta cccacttgat
     7921 ttctgatacc gagccaatct tggatgaaat tgtcttccta aaagacggaa aagtcgtccg
     7981 tcaaggaaat gtagatgata ttcgctacga gtcaggtgaa tccattgacc aactcttccg
     8041 tcaggaattt aaggcctaag caaaggagat tatttatgtt ttggaattta gttcactacg
     8101 aatttaaaaa tgttaacaag tggtatttag ccctctacgc agccgtgcta gtcctttctg
     8161 ccctcatcgg aatacagaca caaggcttta aaaatctacc ttaccaagaa agtcaggcta
     8221 ctatgctact ttttctagct acagtctttg gtggcttgat gcttacactt gcgatttcaa
     8281 ccattttctt gattattaaa cgcttcaaag gtagtgtcta cgaccgacaa ggctatctga
     8341 ctttgacctt gccagtttct gaacaccata tcatcacagc caaactaatc ggtgccttta
     8401 tctggtcatt gattagcacc gctgtattgg ctctaagtgc tgttattatt ctggctttaa
     8461 cagctccaga atggattcct ctttcttatg tgattacatt tgtagaaaca catctccctc
     8521 agatctttct tacaggtata tccttcctac taaataccat ttcaggaatc ctctgcatct
     8581 acctggctat ttccattgga cagcttttca atgaataccg tacagcactc gctgttgcag
     8641 cctacattgg tatccaaatc gtcattggat ttattgaact tttcttcaat cttagttcca
     8701 atttctatgt caattcactg gtaggactca atgaccattt ctatatggga gcaggtatag
     8761 ccattgttaa agaactcata ttcatagcta tcttttatct cggaacctac tacatcttga
     8821 gaaataaggt taatttgctt taaataattt ttacctagat atgtaacata ctcatagaac
     8881 aaaagagacc aggcaaaaag tctttaaaat tagaaaacgc atagtatcaa gtgttaaaaa
     8941 tccttgatat tatgcgtttt ttgtgagctg acttatttcc tttcgctata tcgcaaaatg
     9001 aaataagaac ggaacgatgg gattttggaa ttcaaatcaa tttataagaa tgttttagaa
     9061 gtaatattat cctattccag attcagttca ctatacaatt gagttttcaa gcaacctgtt
     9121 tacataatgt gtacataatt aggttcgtga ttccaccctt ttcaccttta aaaacctcgc
     9181 tttcgcaagg ctcttctatt tataagataa ggcacgttta aaggttttcc aaatccctaa
     9241 atcatccgtt tgaagaacga gactagcata catgcgtccg ataaatcctg ttgctaccac
     9301 cgcaaaaatc actgtaatag caagtgaaat ccatgcttct gctccccccg catagccatt
     9361 aatcgttcga aacggcataa agaaggtcga aataaaggga atataagaac caatcttcaa
     9421 gaggagattg tcaccagctg cacctagagc tgtcactcca aaaaaaccac ccataatcaa
     9481 aatcatcaaa ggcgacaagg ctttccctga gtcctcagga cgagaagcca tagatcctag
     9541 gaaggctgcc aagactacgt acatgaaaag actgatcaaa ataaagagca gggtattcag
     9601 tgagatagca tctcccaagt gaaccaaaat accagactga gccaagaatg gcaaatcttt
     9661 aaagagcaaa acggcagcca gaccacctac aacatagatc ccaatatgcg ttaaaatcac
     9721 tagaaacaga gccatcatcc gcgcatagaa atagtgactt gcccttatgc tagaaaaaac
     9781 gacttccata attttggtgc ctttttcact ggcaacttcc tgagctgtta cacccgcata
     9841 ggtaatcaga atcatataaa gaaagaatcc taaggcacct gctgcaattg tttgaataaa
     9901 ctttttattt tccttggctt catcaatctt ttctgtgaat tgaattgtct gcgctaagcg
     9961 tttttcctgc tcttgagaca aggaagcagt tgaacgatta agctgatttt gcagttcatt
    10021 gagtgtacct gtaacctcaa atttaattcc attttcaagc gatgtttcgc catgataaac
    10081 tgcctttaga acactatctt cttgatcaat ggtcaaataa ccttttaatt tttcttcttt
    10141 aattgcttct ttggcacttg cttcgtcttt atagtcgaag ttaacaccat ttacattctt
    10201 cagtccttct gctacagatg gcactgttgt cactactgcc actttattat ttttagccat
    10261 agaagaacct tggatatgcc caattcctac agagattcct aaaaagagga acggcgaaat
    10321 caccataaag aagaaactcc atgacttgac atgtcgaaga taggtttcct tgattacaac
    10381 ccacatattt ctcatacttc cactcctgat tctagtttaa agatttcatc gatagttggc
    10441 gcttgttggt caaatgttgc gatatattga ccttgagtca agattgggaa gagttccctt
    10501 ccagcgctct catcctccaa aatcaatttc caactgcctt gtttggtcaa gctcacctgt
    10561 ttgacatgag gaagattttc caattcttcc ttgcttcgtt cacttgaaac aaagagacgc
    10621 gttttcccgt attgattgcg gacatcctga attggtccgt gcaagaccac acggccatct
    10681 cggatcatca gaatatcgtc acaaagttcc tcaacattgg tcatgacatg gtcagaaaag
    10741 ataatggttg ctccgcgctc tttttcctga aaaatgactt gtttgagcaa ttctgtatta
    10801 actgggtcca atccactaaa aggctcatcc aagataatca ggtctggttc atgaatcaga
    10861 gtaataatga gctgaatctt ctgctgattt ccttttgaca gactcttgat tttatctgtc
    10921 agctttcctt ttacttccaa cctcttcatc cattgaggga gtttttcttt gacttctttg
    10981 gcatccatgc cttttagagt cgccaagtag cgaacttgtt caagaactgt caatttaggc
    11041 atgagactgc gttcttcagg cagataacca atccgagcat aggtctcctg acgaatatcc
    11101 tgaccatcca gaccgatttc tccctgatat tctaggaatt ttaaaatact atggaaaatc
    11161 gttgtttttc cagcaccatt ttttccgact agtcccaaaa tacgacctgg tcgcgcttga
    11221 aagtcaatac caaacaaaac ttgcttggat ccaaaacttt tctctagact tcttacttct
    11281 agcatctttc acctccgaaa tttcttgcac tcattatact cctttttgat agcctttaca
    11341 atgttttttg tccattttta gaagactatt gctgtgtaaa atatggcctg gagcactttt
    11401 atactcaatg acaatcaaag agcaaactag gaagctagcc gtagactgct caaagtacag
    11461 ctttgaggtt gcagataaaa ctgacgaagt cagctcaaaa cactgttttg aggttgtgga
    11521 tagaactgac gaagtcagta actatatcta cggcaaggcg aagctgacgt ggtttgaaga
    11581 gattttcgaa gagtattagt gataaatcca ttatacagca gcaaacttaa tttatacctt
    11641 ccgctcctca actgtctatt tttaatcctg aattgttatt tgagtaactc ctttttcctc
    11701 gtaaagtttt cttcctctaa aacttctgga aaaaggctaa tagtttcaga caacattttt
    11761 ataagaaaca agttcatctg tcatttcaag aaggagtaat cctttatcta ctaatggacg
    11821 gaacagaatt caaccgcttg tccgatatgt tttctaagga ttatatagta aaatgaaata
    11881 agaacaggac aaattgatca ggacagtcaa attgatttct aacaatgttt tagaagtaga
    11941 tgtatactat tctagtttca atctgctata tctattatgc acaccactat aggatctaat
    12001 aaaaatcaca acaagttcat tcatagatgg ttacctcagg gaactaagaa aacgactaca
    12061 aaggaagtcg cattcatcga aaagtggatt aacaactatc ctaaaaaatg cttgaactac
    12121 aagtccccca gagaagactt ctggatgact aacttgaact tgaaatttag caataattaa
    12181 ttcaccatct aactatattt agtaattatt tcagaactga ttaatattaa aattaactaa
    12241 caattcaaag gattcatact agccataaat tacgtccatc agagagagac tcttactact
    12301 tttagatttt agtctttcta gcttcagaat acatctaaac tttagggaaa atgactattc
    12361 gaaaacgcga atgcctcaaa attatctcag ataagctatt cgaaacttag aatgctttta
    12421 aatttatgga attgcgatta ttcgaaacct agaatgcata taacctttag ttgacagacc
    12481 tattctaagt ctcgaagggc tatttacttt ctattcctta tcaaaaaaga ctcattcccc
    12541 ctttctcctc caaaatatgg tatagtagaa atatactatc tatgaggagt ttacatgtca
    12601 caggataaac aaatgaaagc tgtttctccc cttctgcagc gagttatcaa tatctcatcg
    12661 attgtcggtg gggttgggag tttgattttc tgtatttggg cttatcaggc tgggatttta
    12721 caatccaagg aaaccctctc tgcctttatc cagcaggcag gcatctgggg tccacctctc
    12781 tttatctttt tacagatttt acagactgtc gtccctatca ttccaggggc cttgacctcg
    12841 gtggctgggg tctttatcta cgggcacatc atcgggacta tctacaacta tatcggcatc
    12901 gtgattggct gtgccattat cttttatcta gtgcgcctat acggagctgc ctttgtccag
    12961 tctgtcgtca gcaagcgcac ctacgacaag tacatcggct ggctagataa gggcaatcgt
    13021 tttgaccgct tctttatttt tatgatgatt tggcccatta gcccagctga ctttctctgt
    13081 atgctggctg ccctgaccaa gatgagtttc aagcgctaca tgaccatcat cattctgacc
    13141 aaacccttta ccctcgtggt ttatacctac ggtttgacct atattattga ctttttctgg
    13201 caaatgcttt gacacgtaaa aaatccgttt ggtttcccaa gtggattttt aaagcgtaga
    13261 ttaactatag cttgatacta aatatacttt ggtatggaaa ttatgcatat ttttcgatag
    13321 tgaggcgagg acttacctag cctttccgcc gtgatagaaa cacctgaaat ctaatggttt
    13381 caggtattcg gaaactttga gacactaggc tcaaagttta ggtatggaat ttcgaagaaa
    13441 gtcgctaccg tccgtaatca cttaaggaaa ggctcaaaaa tattgttttc aaccacaaaa
    13501 tccgtttggt ttcccaagcg gattttgtgc tttattttga aacttctttt gcaagaacaa
    13561 agttcccaag tgtggcagaa ccatttcctg cgactgctgg cgtcacgata tagtcacgca
    13621 catctggtac tggtaggtaa ccattaagaa gagatgtaaa tttctcacgg acacggtcca
    13681 gcatatgttg ttgagccatg acccctccac caaagacaat cacgtctggg cggaaagtca
    13741 ctgtcgcatt aaccgcagct tgagcgatat agtaggcttg aacatcccaa acagggttgt
    13801 tgagttcaat attttcccca cgtacacctg tacgagcttc caaacttgga ccagctgcat
    13861 aaccttctag acatccctta tggaaaggac aaacaccctt aaactctttt tcaatatcca
    13921 ttgggtgtct agcaacataa taatgaccca tttcagggtg acccacacca ccgataaact
    13981 caccacgttg gatgacgcct gcaccgatac ctgtaccgat tgtgtagtaa accaagtttt
    14041 cgatacgacc accagcattg ttacgggcaa ccatttcacc gtaagcagag ctgtttacgt
    14101 ctgttgtgaa gtacattggc acgtttaggg cgcgacgaag ggcaccaagc aagtctacat
    14161 ttgcccagtt tggttttgga gtcgtcgtga taaagccata agtttttgag tttttgtcaa
    14221 tatcaatcgg cccaaatgaa ccaactgcaa gaccagcaag gttatcgaat tttgagaaga
    14281 actcaatggt tttatcgatt gtttcgattg gagttgttgt tggaaattgt gttttttcta
    14341 caacgttaaa gttttcatca ccgacagcac agacaaactt tgtaccgccc gcttccaagc
    14401 ttccatataa ttttgtcatg ataaacctct tgtttttatt ttctttatta tagcatactt
    14461 cgaaagtcta aatgtctcta ttttttagat tttcctctgt aaatcttact atctaataaa
    14521 aacgaacaaa catgtcattt gttcgttttc acattagaga ggattgatta gattttcact
    14581 tcgatcacag catccccctt cgaaactgaa cctgttgcga ctggagctac tgaagcgtag
    14641 tcagctgtat ttgtaacgat aaccattgtt gtatcatcaa gtccagctgc agcgattttg
    14701 tttgagtcaa atgttccaag aacatcgcca gctttcacct tattaccttg agcaactttt
    14761 gcttcaaaac cgtcaccgtt catagataca gtgtcaatac caacgtgaat caaaacttca
    14821 gcaccatttc ttgttttcaa accaaaagcg tgccctgttg gaaaggcaat tgaaacttca
    14881 gcatcagcta gtgcatagac cacgccttga cttggtttca cagcgatacc ttgtcccata
    14941 gctccacttg agaagactgg gtcattgaca tcagcaagag cgacaacatc accgacgata
    15001 ggagttacaa gtgtttcatt ttgaagagct gctggcgcaa cttcttcttt ttcttcagcc
    15061 acttcagctt gttttgcagc tgcagttgcg tctacttcat cttcgtaacc aaacatgtaa
    15121 gtaagagcaa aaccaagggc aaatgataca gctaccataa gaaggtattg tggaagttgt
    15181 ccgttaccaa cataaagcat tgtaccaggg atgatggtga taccattacc agtaccagca
    15241 agtccaagga tagaagccaa tccaccaccg attgcaccag caatcaatga aaggaagaat
    15301 ggtttacgga agcgcaagtt caccccgaag atagcaggct ctgtaatacc taggaaggca
    15361 gaaagagcag ccgggaaagc aagtgttttc agttttggat tttttgtttt aacaccaacc
    15421 gcaacagtag cagcaccttg agctgtcata gcagctgtga tgatagcgtt gaatgggtta
    15481 gcatggtcag cagcaagtaa ttgcacttca agcaagttga agatgtggtg cacacctgac
    15541 acgacgatca attggtgaac cccaccaatc aagaaaccac caagaccaaa tggcatgcta
    15601 agaatcgctt ttgtagcaat aaggatgtag ttttcaacaa cgtggaaaac tggtccaatg
    15661 acaaagagtc caaggataga catgaccaaa agtgtcacga atggtgttac caagaggtca
    15721 atgacatctg gaacaacctt gcggacagct ttttcaaatt tagctccgac aaccccgatg
    15781 atgaaggctg gaagaacgga accttgcaaa ccaacaacag ggatgaaacc aaagaagttc
    15841 atcgctgtta cttcaccacc ttgagcaact gcccaagcgt ttggaagtga gccagagaca
    15901 agcatcatac caagaacgat accaacggca ggatttccac caaatacacg gaaggttgac
    15961 cacacaacca aacctggcaa gatgatgaag gctgtatctg tcaagatttg tgtgtaagtt
    16021 gcaaagtcac ctggaagtgg catttcaaga gcgttgaaaa gaccacgcac acccatgaag
    16081 agacctgtcg ctacgataac tgggatgatt ggaacgaaaa catcaccgaa agtacggata
    16141 gcacgttgga accagttccc ttgtttagca acttctgctt tcatgtcatc cttagatgat
    16201 gttggtaagc caagtacaac aacttcatcg tacattttgt taactgtacc tgtaccaaag
    16261 ataatttggt attgccctga gttaaagaaa gcaccttgaa ctttttccaa gttctcaatc
    16321 acttctttat tgattttctc ttcatctttg accatgacac gtagacgagt cgcacagtgg
    16381 gcaacactat tgacattttc acgtccgccc aaggcatcga tgactttttt tgcaatttcc
    16441 tgattgttca tttgcaaaaa tctccttata taacattttg ttcttgtttg aaagcgattt
    16501 tattcgccct tacgactatt attttatcat gttttaaaaa tatgtcaagc gttttgcaga
    16561 aaaaatattc tatccactta gtgggcaagt tttagattga ttgtttttga ctgtttcatc
    16621 aggaattcct tgaaaaataa gtttgaaacc ttggttaaaa agtcttttat ttcattatct
    16681 ttcacatttt cgtaaaaatt tgattgattt cctgtattta ttttatgata atcgtttgac
    16741 agtttttcct cttttttaac ataaaaggct tgcatttttt atcgaaaaca gttactatta
    16801 aaagtgataa gatttttgga ggaatgaatg gaatggacaa ctgagcgtcg ttacagactt
    16861 tatcaagatt ggacgcaaga agaaattcaa catataaagg aaaatatggc acaatctcca
    16921 tggcatactc attaccatgt tgagccaaaa acaggacttc tcaacgaccc aaatggcttt
    16981 tcttactttg atggcaagtg gatcctcttt taccagaatt ttccttttgg tgcagcccac
    17041 ggtttgaaat cttgggcaca gctagaaagt gatgatttgg ttcactttaa agaaactgga
    17101 atcaaagttt taccagatac tccattagat agccacggtg cctactctgg ttctgccatg
    17161 caatttggcg ataacttatt cctattttat acaggaaatg ttcgcgatga aaactggatc
    17221 cgtcacccat accagatcgg tgctttgatg gacaaggagg gtaagattac aaagattgac
    17281 aagatcttga ttgaccagcc agcagactct actgaccact tccgcgatcc acaaattttt
    17341 aactttaaag gtcaatacta tgctgtcgtc ggtggacagg acttggagaa aaaaggcttc
    17401 gtccgtctct acaaggctgt caataacgac tacacaaact ggcaagcagt tggcgacctt
    17461 gactttgcta acgaccgtac tgcctacatg atggaatgtc ctaatctggt ctttgtagag
    17521 gaacatcctg tccttctcta ctgtccacaa ggattggata agaaagttct agactacgat
    17581 aatatctttc caaatatgta taagattggg gcttcctttg accctaaaaa tgccaaaatg
    17641 gtagatgtgt ctcaacttca aaacatggat tacggtttcg aagcctatgc aactcaagcc
    17701 ttcaacgctc ctgatgggcg tgctctagca gttagctggc ttggtttgcc agatgtttct
    17761 tacccatctg accgttttga ccaccaagga accttctctt tggtcaagga actcactatc
    17821 aaagacgaca agctctacca gtatccagtc gctgctatta aggaccttcg tgcttctgaa
    17881 gaagccttct caaaccgttc ccaaaccaag aacacttacg aacttgaact caacttggaa
    17941 gctaatagcc agagcgagat tgtcttactt gctgataaag aaggtaaggg actttcaatc
    18001 aactttgacc ttgtaaacgg tcaagtgaca gtggatcgta gccaggctgg agaacagtat
    18061 gcccaagaat ttgggacaac tcgttcttgc cctatcgaga atcaggctac tactgctaca
    18121 atcttcatcg ataactctgt ctttgaaatt ttcatcaata aaggagaaaa agtattttct
    18181 ggtcgtgtct tcccacatgc ggaccaaaat ggtatcctga tcaaatctgg aaacccaact
    18241 ggaacttact atgaattaga ttatggtcgc aaaactaact gatgtcgcca aacttgcagg
    18301 cgtcagtcct actaccgttt ctcgggttat caataaaaaa ggatatctat ctgagaaaac
    18361 catccaaaaa gtcaatgaag ccatgagaga attaggctat aaacccaaca acctggctcg
    18421 tagtctgcaa ggaaaatcag ctaagttaat cggcttgatt ttccccaata tttccaatgt
    18481 tttctatgca gaattgattg ataaattgga acaccaactc ttcaaaaatg gttacaagac
    18541 catcatctgc aacagtgaac atgattctga gaaggaacgc gaatacatcg aaatgttgga
    18601 agccaatcag gtagacggca tcatttctgg tagtcacaac ctaggaatcg aagactacaa
    18661 tcgtgtgaca gcgccgatta tttcctttga ccgaaaccta tcgccagaca tccctgttgt
    18721 ctcctctgac aactatgctg gtggggttct tgctgcccaa accttggtca agacaggtgc
    18781 ccagtctatc atcatgatta cagggaatga caattccaat tcgccaaccg gactgcgcca
    18841 cgctggtttt gcatccgtac tcccaaaagc tcctattatc aatgtttcca gtgacttttc
    18901 tcccgtcaga aaagaaatgg aaatcaagaa tatcttgacc cgggaaaaac cagatgccat
    18961 ttttgcttcg gatgatttga cagctattct ggtcattaaa atcgctcaag aattgggcat
    19021 ttctgtccca aaagagctca aggtcatcgg ctatgatggg acctacttta tcgaaaatta
    19081 ctaccctcaa ttggctacta tcaagcaacc tttggaagag attgcttgtc tcactattga
    19141 tcttctcttg caaaagattg aaggcaagga agtcgccaca actggttact tcttaccagt
    19201 tacgctatta ccaggaaaaa gtatttaaac acaagaaaac tcagaccgat tcgtctgagt
    19261 ttttatgatc ttaaattttc gagatagcgc tgggctgtct ctaggttaaa ggttttatct
    19321 gagatgaggc gctctactag gggagcaact tcagattcac tagccccagc taggagagct
    19381 agggatttgg cctgtagttt catgtggcct tgctggatgc ccgtacttac caaggctttg
    19441 agggctgcaa aattttgagc aagaccgatg gacacgataa tctgggctaa ttctctggca
    19501 gaaggatttc ctagtagatc atgactgaga gctacacgtg ggttgaggcc gatagagcca
    19561 cccttagtcg ctacaggcat gggcagggtc atctcaccga ccaattcttc tctttcaagg
    19621 tccagcgtcc agcagctaag accttgatag cgtccatctc gactggcaaa ggcatgggcc
    19681 ccagcttcga tggcacgcca gtcattacca gtggcaatca aaatcgcatc aataccatta
    19741 aaaattcctt tattatgagt agcagctcgg taaggatcag cctgcgcaaa ctgactagcc
    19801 aacgcaattt tctccgcaat ctctcgtcct tgatactttt ggcggctcaa gtagcgaaag
    19861 gcgatgcgac agcttgcagt caccagagaa tcagtcgcgt agttggacag gattcccatg
    19921 agactctgtc cctgactgag ttcttctaag actggtttca aggcttccag catggtgttg
    19981 agcatattgg cacccatggc ttcctgggta tcgacatgaa tataaacaac gagaaagtct
    20041 ggttcgcctt ttatctgctc gacatgcaga tcacgcgccc cacccccacg tttaacgata
    20101 gaaggatagg cttgattggc aagctccaag agctccgctt tcttgctggc aatcttctct
    20161 tgcgctagtt taggattagc aacttgataa agggctacct gcccaatcat ctggcgctga
    20221 tggacttgtg cagtaaaacc acctgcacgc ttgatgattt tgctggcata gctggccgcc
    20281 gcaaccacag agggttcttc tgtcacatag ggaacggtgt attcctgacc gttgacaagt
    20341 acctccggaa ccagcgaata aggcagagaa aaagttccca ccacattctc actcagctgg
    20401 tctgccacag tcacactcat ctgttcatcc ttctccagac tagcttgtct ctcaggacta
    20461 aggagcgcct gagcttttag cagctcgagg cgctcttggt atgatttttt agaaaatcca
    20521 ttccaactta tcttcattat ttttcaacct tgctataacg gcgttggtgg tcaagaattt
    20581 caaccaaggc aaaatcttga ttttcatagc cagcaaactg ggcagagttt gtttcatcca
    20641 agtttacttc ctcaaaaaag accttttcat agtctgcaac ggataaggca gttcgttggt
    20701 tgagcttgtt caaacggtct ttatccaaat aagcttcata tccttcaacc aattcaccac
    20761 tgaagaactc agccacagct ccacttccgt aactataaag ggcgatttta tccccagctt
    20821 tcaagctatc tgtattttcc aagagagaca aaagtccaag gaaaagtgaa cctgtgtaga
    20881 tattccccac cttttgactg tagagaatag actggtcaaa atgcttttgt aagaggtctt
    20941 ttttctcttg aggcaggctc ttatccatga tttttttcaa gccttttagc gctaatttag
    21001 gataaggcaa gtggaaacaa acagccgcaa aatcatccaa agtaagctgg tagcgttttt
    21061 gatattcaag ccaagtcgtt ttcaaactat ccaagtattg ttgggtagaa tagacaccat
    21121 ttacataagg agttgtcgag taatttggtc gccagaaatc catgatgtca cgggtctgag
    21181 ctacattgtc attattaaag gccatcatgc gtggattttg tgtaatcaac atagctacac
    21241 ttccagcacc ttgagttggt tctcctggag tttcaatacc gtatttggca atatcactgg
    21301 caatgaccaa gaccttggac tccggagaat tttccacatg caatttggca taatggaggg
    21361 cagcagtcgc cccatagcag gcttctttaa tctcgaaact acgagcaaag ggctggatgc
    21421 ccagcaagcc atgcacaaag acggccgcag ccttactctg gtcaattcct gactcggtcg
    21481 ccacaatgac catgtcaact tcttgtcttt cttgctcagt taaaatagag tcactagcac
    21541 tggccgccaa ggtcacgata tcctcagtta ggggcgcaat actcaattcc ttgagtaaga
    21601 gtcctttact taatttttca gggtcaattc ccctcgcttc tgctaagtct tgtaatttca
    21661 agacatattg actggtcgca aaaccaatct tatcaatacc gattgtcata tttacctctg
    21721 ttttatcatt catgtaaaaa atcgttctat actattttat cacaaatggc agtaaaagag
    21781 agaaaaaaga cttgattcac caaatcaagc ctcttattgg tcatcatttt aaagaatgat
    21841 tagttgctag agagttcacc gatataagta gctttataag ctccattcac agttatcagc
    21901 tcctggagga tcaaatttcc tgagtaagtc cttcccatct catctacaaa tttttgataa
    21961 aactgactgg tcggaatttc tctgacatcc ttatcaaatg tcttatcaag tgttttacta
    22021 accttctcag caatcaattg atgctcttgc catccacttt gaaactctga gcccgaacta
    22081 gaaaccatga ctgggataaa caacaaggtc agtagactta cagacaataa ggaaaatagt
    22141 agacttcctg caaaactaga atcctagttc atgattgata ataccagcaa tcaaattcat
    22201 tcgtaatccg aagcgtttac gatgatttcg ataggttgtt gaaaatattt taaacgtttt
    22261 tactttggca aagatgttct caaccttgct tctctcctta gatagcgcat ggttataggc
    22321 tttatcttca gctattagcg gcttgagttt gctggattta cgtggagttt gtgcttgagg
    22381 atatatcttc atgggccctt gataaccact gtcagccaag attttaccag cttgtccgat
    22441 atttctgcga ctcattttga acaacttcat atcatgacaa tagttcacag tgatatccaa
    22501 agaaacaatt ctcccttgac ttgtgacaac cgcttgagcc ttcatagcgt ggcatttctt
    22561 tttaccagaa tcattcgcta attctttttt tagggcgatt gatttgtact tccgtcgcat
    22621 caatcattac cgtgtcctca gaactgagag gagttcttga aatcgtaaca ccactttgaa
    22681 caagagttac ttcaacccat tggctccgac ggcttaagtt gctttcgtga ataccaagat
    22741 cagccgcaat ttcttcataa gtgcggtatt ctcgcacata tagaaagcgt tgttaattta
    22801 tttatctcat ttttcagaaa attcttttat ttctgtaaag tctacgatac tcgatgtgtc
    22861 tttatataat gatacagtct gagaatcact gttccgctag ccattccaat agagattacc
    22921 agagccaaca tgacaaccaa ggtcgcactt gccagtgctt tattatagtc ccctgtcaca
    22981 aaaaaggcag ttgttcggta ggagagataa cctggaacca gcggtgccaa aatggccaag
    23041 ataaagacca cagcaggtgt cttataaaga atacttaaaa tctggctgac acaagaacca
    23101 ataatggctg caatgaaggt agctacaatg acattggtcg gttccttgag caagagatag
    23161 attagccaga cagtcatgcc caaaatccct ccaggtaaga gcatagaccg ttgcacattg
    23221 agtacgatta aaaaagtgat aatggcaaga aaacttgcta ctgcttgtaa taaaaaggtt
    23281 gttagtgtca tattagttca tcaataccaa ggcgacagaa gttcctgccc ctaaagcgag
    23341 ggtaatgagc agggattcaa acatcttact cataccagag tttatgtggt tggtcataat
    23401 atcacggacc gcattggtca aggcaatacc tggtacaaac ggcatgaccg caccagctat
    23461 aatcaaatct gccgttgaag gaaaacctgt gtagcgagcc caaaactggg caattatccc
    23521 aaagacaaag gctccagcaa aggctgtcac aaagggaatt cggataaatt tttccacata
    23581 gagggaaaag gcaaaaccaa ataaggtcgc cactcctgcc ccaagtgcgt cgtagatatt
    23641 tccgctaaac ataactgaaa agaaaggagc actaaaggtc gcagccagag ttacctgcaa
    23701 cttagtatag ggaaggggtt gagcttgcaa ggccgtcaat tgcttaaagg ctgtttctaa
    23761 gtcaatctgc cccccaacta gctgacgaga aatctggttc acatcgcaga ctttttcgat
    23821 gttataagaa gaggaggtca cgcgcttcat gcgcgaaata ttggtatttt caatagagaa
    23881 aaagatagcg gcaggcatgg caaggacatt gcaatccaca atcccctgcg aatgcgcgat
    23941 tcgaatcatg gtatcttcta cacgatggat ttctgagcca cttttaagga gaatagtccc
    24001 cgctagcata atcacatcaa tgacggcatt taattctttt gattcttcca tgctttcctc
    24061 cttttatcaa ctccctctat tctatcacaa atctggactc aaaaaaaatc tttgccatga
    24121 aatcatgaca aagattgatt actcattttg attatccatc tacttttaag gagtagctga
    24181 agttgtttta ggtttgtaga ttgaaatctt gactctagtc ttatttaggt ctaccttttc
    24241 acctgctcta ggactttgtt caacaaccat gccttctgca ctacctgcag gcgctgtcgt
    24301 cacttctaca acttctatat tagcttcctt aatcccaaca atttgaatca aattgttctt
    24361 agtaaactcc aagctggaac caatgtaact cggcatggca acacttgtaa cttttttagc
    24421 tactgtcaag acaatttgag taggtttact cacatcataa gtcgttccgg cacctggact
    24481 ttgtttcata atcgttcctg gttcgctttc gctggactct tcttcctcta tcttaatcaa
    24541 attctcagga accttcttct gcttgagttc tgagattact tctgtagagt tccgtccaat
    24601 atagttccct aattgaatcg tcgtagcttt tttagctact gtcaaaataa tttgagttgc
    24661 cttgctcaag tcataggtcg taccttctgg tagactttgc ttcaggaccg ttccagcctc
    24721 actctcattc gactcttctt cctcaatttt aatcaaatta tctggaactt ttttctcttt
    24781 taattccgcg ataacatcag aagatttccg gccgacataa ttactaattt ggaaggattg
    24841 tttgcctgat gagacaacca gattaatttt cgttccttct tttcgaccag ttccagcgcc
    24901 aggatctgta cggataatcc gcccttcttc caccttttca ctagcctctg tcttctcctc
    24961 accaatctca aaattggctt ttttgagcgt tgccttggcc tctgcaactg tctgacctgc
    25021 cacatctgga atggcaatgg ttgcaggagt tctggatagt atccaaataa gagaagctgc
    25081 caccaataca aggctggcca acaaaatcag gtaacgcatc ttaaatctat gttttttcgg
    25141 tgcttgtggt tggtaagttt cctctgtcac agcctggctt gggtttttga ttgatttgtg
    25201 ttctgtctgc gcttgaacct taggaataga tgtcaaggta ctctgagaaa ccttcggcaa
    25261 ggtcttggta tctgccttgc tcgtttcatc aaagattaac ttactttcat ttctacgatt
    25321 gtaggacaag ctactagaca agtctacata catctctgaa accgagcgat agcgattggt
    25381 caacttttta gcagttgcct tgataataac attttctaaa gcctgaggta cagatggatt
    25441 ttctgcaata acggacggca ggggtttctg gaaatgctgg agggcaatgg tcaccgcgct
    25501 atccccgtca taagggatat ggcctgtcaa catctcatag aaaataatcc ccatggcata
    25561 gatatcactc tgcacagtcg ccttcgaacc acgcgcctgc tctggtgaca agtaatgaac
    25621 tgagcccaac atcgagttag tctgggtcag acttgtctct gcaaaggcta cagcaatccc
    25681 aaagtctgtg accttggccg tcccatctgg tgtcaaaagg atattttgag gtttcaagtc
    25741 cctgtgaaca attcctcgag tatgggccaa gcgcatagcc aagagaattt gtcccatgat
    25801 acggactgct tcttcattag aaagaggata atgttccttg atatagcgtt tgaggtctag
    25861 tccagcaaca tactccattg caagatactg ttgaccgtct tcctcaccaa tatctgttat
    25921 ccgaacgata tgaggatggt ctagatctgc catagctctc gcttcacgct gaaaacgagc
    25981 tacagctatc gggtccgtct ggtagttggt cctcagaacc ttcactgcca cttcttcccc
    26041 atctaagatt aagtctttgg ctaggtagac atccgccatg cctcctcgac caatctgttt
    26101 gacaatccga tagcgtccgg caaaaatctt gccgatttgg atcattctgc atcctcctcg
    26161 ttcatagaaa caagggcaac cgtaatgttg tctaaacctc ctgcattgtt agcaaaacga
    26221 acaagtgtct ccgttttatc tgctaaagga atatcactgg ttacaatatc acgaatctca
    26281 ctgcctgaaa tcatgttggt caagccgtca ctattgagca agagatagtc acctgactca
    26341 aggataactg tcccaaaatc aggctgaatt tcatcttttt gcccaataga ctgggtgata
    26401 atattttttt gcggatgagc ttctgcctct tctggtgtca attgaccagc cttgagcaat
    26461 tcattaacca aggaatgatc gctcgtcaac tgatggtatt cttctccacg aatcaagccg
    26521 atacgcgaat caccaatatg agcatagata gcctgattat caataatagc aaggacttcc
    26581 aaagtagttc ccatgcctct gtaagcttca tcctgaccaa gctggtgaat cttttgattt
    26641 tcaatttcta ggtaatgggc gaaccattca cgcacttcat tgactgtatc gatctgggta
    26701 tcaacccaag ctacacccag gtctgtgacc gccatttcac tagcgatatt ccctgcacga
    26761 tgacctccca tcccatcagc taaaataatc atggtacgtc cagctctatt gacatagtgg
    26821 ttgacatagt cttggttatt tgttcgtttc tgaccaacat ctgttaataa tgaaatttcc
    26881 atgtgtcagt tccttcctaa tccgatatct tgcgaaattg actgatgaag aatccatcac
    26941 ttccatacaa ttcaggtgta atgaggatac agccgtcttt catgatatcc ttacattcat
    27001 gttctagttt tacctgctcg aactcgggat gactctctaa aaaggcctta acaacttgaa
    27061 aattctcctc tgagacgata gtgcaggtgc tataagttat tataccacct ttgcctagta
    27121 tttgacaaac actacctaat atttctaact gaatttcctg caaggacgcg aaatctgccg
    27181 tttctttatt gtatttgata tctggttttc ggcgcaaaag accgattcct gaacaaggag
    27241 catccaccaa aatcttatca aaggaatcct ggtcaaaaaa ctcatgcacc tttctggcat
    27301 ccaatttttg agtttgaacc cgatctgcaa ctcccagacg ttgggcattt tcttgaatta
    27361 aatccaactt gtggtcgtac aagtccagag cagtaacctg acctgtcgta agataagagg
    27421 ctatatgggc tgttttccca cctggagccg cacaggcatc aagcactcgc tcatcacctt
    27481 gtaaatcaag cgtcggagca accagctgac tggactcgtc ttggatggta atggctccat
    27541 ccgcaaacaa attatgccct gcaaaatgcc cctgctcctt aaccagacca gtggttgcta
    27601 aaagggaatc attcgcctcc aacaaggctt ggatttcctc ttttcgactt aggtctgtta
    27661 cacgaatact ggctttgttt cgcactaaca ggctttcaaa gatggctttt gctctctcct
    27721 ctccgtattc ttccttgagt ttggcaacta gccaaactgg gagagaatag gcaatggagt
    27781 cacgcttgtt ttttcgcttg atgctagcaa tatctggcca gccttcacgc aagatacggc
    27841 gaaggacagc gttgaccaat ttttcactgc cttttttacg gagtttggct aattccactg
    27901 cttcattgac cacagcatga tctggaattt tgtccaaata gcggagttgg taggcactca
    27961 tgagaagaag gacatagagc cagctgtcta actggtctct gtcttcgata aagtgggata
    28021 ggtaccattc cagagtcagt ttacgggcta ccgttccata gactagctcg gtcactaagc
    28081 ccttgtctgc tgcagagagc tgactcccct tgaggtgttt atttaaggca atatttgaat
    28141 atgcttgatt cacaaaaaca tcctctagca ctgctagagc taaacttcta gccgtttcta
    28201 ctttagtcac caaatcgttc tcctacagtc aatgtacgtc caactccatt gaggaaggaa
    28261 gcaatgtcca tcttaggctt accagctggc tgcacttgtt tgagggatag agccccttca
    28321 gccgttgcga caatcaattc tttcttgccg atagagagaa tctcacctgg atttccctga
    28381 ccttctactg gtagggcttc ataaatctta aagcggtcgc ccttaaggaa agtatgggca
    28441 acaggccagg ggttcattcc acgaatttgg ttaaagagtt gacgattggt tttgttccag
    28501 tccagttttt cttcctttgg ctttatattt ggagagaagg taacctgact cgtatcctgc
    28561 ggttcaggtt tgatatcacc agcaatatag gcaggcagag tgtccaaaag caaatcacaa
    28621 ccaactagcg ccaatttttc aaacaaggtg ccaacattgt cctcatctgt gatcggaatg
    28681 ctgcgacgag aaatcatatc tcctgcatcc atttccttaa ccatttccat gatggtcaca
    28741 ccagcttcct catccccttg aatcaaggca taatggatag gcgcaccacc acggtgtcta
    28801 ggaaggaggg aggcatgaac gttgacagca aagtccatgc tatcaaggag tttgcttggg
    28861 agaaactgcc caaaagcagc agtcacaatt ccatctgctc ctagcttcat aagatcttcc
    28921 atctctggac ttccagataa tttttcaggt tggtagatag atagtcctgc ttccttggca
    28981 gcctgcttga ctggggtttc ttggataact tttttacgac caacagcacg gtctggctgg
    29041 gtcacaacgg ctagaatttc gtaacggtca tctgtcaaaa gtccttttaa gactgttgct
    29101 gaaaagtcgg gggtccccat aaagattagt tttgtcatat cttctccttc ttataaaaat
    29161 tgctgcggct catggtcaat gctgagacgg agctcactat tttcccgttc ttgagtcaag
    29221 gccaagacct ggttgagggt cggccccagc tcatcttcta aacggtattt aattaaaatc
    29281 tggtaatgat agaggttgtg ggtacgggca atcggttttg gcgttggccc cagaatggga
    29341 ctggtctctg acaagcctga ccgcaaaatg ttcatgactt cataggcacg tttgaaaacc
    29401 tcttcttctt tcttgtgaga aagggtaata ccaatcgtga aatagtaagg tggatagccg
    29461 agttgtcgtc tgattcccat ttcataggca taaaagcctt cgtaatcttg atccttggca
    29521 aatcgaatag catagtgctg cgaattgtag gactgtatca agacttgacc tgctttttca
    29581 gcccgacctg ctcgacctgc cacctgagtc aagagctgga aggttctctc agaagaacgg
    29641 aaatcaggca gattcaaggc cgtatccgca tttagaactc cgactagggt aacattggga
    29701 aaatccaaac cctttgcaat catctgagta ccaagtaaaa tatccgcttc ccctcgccca
    29761 aactggtcaa gcaaggcttg gtgactgcct ttctttcgag tcgtatccac atccatcctc
    29821 aaaatgcgag cttggggaaa gagttctgct agctcatcat aagccttctg agttcccgtc
    29881 ccatagtaac gaatactgcg gctcttacag ttaggacaga cctgaggaat atccttcgag
    29941 aaaccacaat aatggcagtt catagtcttg gtatccatat gcaaggtcag agaaatatcg
    30001 cagttgggac aagtatccac cgtcccacac tcccgacaca tgacaaagct agaataacca
    30061 cggcgattga gcatgagaac cacctgctct tttttaacca gacggtcttg gatagcctct
    30121 agcaaaggag gcgtaaagtt tgacgtctca ttttgtccga tatagtctcg aaagtcaatc
    30181 acttgaacct cagggattgt agccaaagga ttggcacgtt gggttagacg taagtgttga
    30241 tagacgcctt tgccagcacg tgcccggctc tctaagctcg gcgttgcaga tccaagtacc
    30301 agagttgctt gattatactg agcccgtaaa atagctacct ctctggcatg gtaacgggga
    30361 ttgctgtcct gcttataagc cgcttcatgc tcttcatcaa taatcatgac acccagattt
    30421 ttcagaggag caaagatagc agatctggca ccaacaacaa cttgggcatc gccacgctcc
    30481 accttgcgcc attcatcata cttttcacca ttggataatc ctgagtgaag aatggctacc
    30541 ttgtccccaa aacgtgctat aaaacgctcg gtcatctgag gagtcaagga aatctcaggt
    30601 accagcaaaa tagctgtctt gcccttatcc agggcacctt ggataatctg caagtaaacc
    30661 tcggtcttcc cacttcctgt aatcccttga agtagaaagg gaggttgaga actgccaata
    30721 gaactcacaa ccgcatcacg cgcctgtctt tgttctggat ttaactccaa aggtctactt
    30781 gcttcaattc cttcaaaata agcagccgag cgttgaactt ccttttggac tatggtaaca
    30841 gcaccttgat ccacaaagaa gttgacttgc tctcgcgagt aggactctaa caagctagcc
    30901 aaggaagcgc tctctggatg agacagcaga taatctctca gttccaactt tttcttggca
    30961 cgtgtagaaa tctcaacacc ttctaattga gcatggtcaa cctcatacca agactgggtc
    31021 ttgaccttct tttgatcgac tgcctgatat tccagaccaa gcaggccttt tctagtcaaa
    31081 cgcatcattt cagcttgctt ggcaaggtct agtgaagaaa aggctagcga atcttctgaa
    31141 ccaaacaggc gcactagttc ttcctgactc aagccttcca gaggatagag aatcttgtca
    31201 tagctagaat tcagaaatcc tggaagcata gccttgagga tagaaatttt gtaggagaag
    31261 acagatttgc gtaactcctc agccagccag agttgttctg gcgtgagaac aggagaaaaa
    31321 tccagcacct ctgcaatatc ttttaaatct tgctccatct cttctccatc tgattgggac
    31381 tccaaaccaa gaacaatccc ttgaatcagg cgattcccct taccaaaagg cacatgaacc
    31441 cgcatcccaa cttccagcat tccctcaaat tcctccggaa tcctgtaact atagggctgg
    31501 tccgtctgca tcaagggcac atctacgata atcttagcta gggccatcgt ctcacctcct
    31561 ccttgtcagt acattcttgc aatagaaaaa ataagattga gtccccccaa ccttaaattt
    31621 tttcaccatc ttctttttct ttagcaattt gctctttgat tttcttttct tcttcttctt
    31681 tgcggcgttt ttcttcttcg atacggcgac gcactgcttc acgttttcct tctggatctg
    31741 ggtgaattgt aacgtttcct gattcgattt cttctaaagc gcgaagagtt gatttttcag
    31801 acttaaaacc ttgagttgct ggggcacctg cttccaattc gtgggcacgt tttgcttcca
    31861 agattacgag tgaatatttt gaaggaacct tgtcgagcaa ggtatcaata gagggtttta
    31921 acatcatttg cttgtaccta ttttctaaat tttatcgggt agttggagat tttggtaaca
    31981 tctcctgata gtgaccaatg acacgatcca cacagaagtg ttctgcttca atcacacatt
    32041 tgacacgttc agcagctagg ggcacctgat cgttgacaat cgcataatca tactcacgca
    32101 tgagggcaat ttcttccttg gccttttcga ttcgttgggc aatcacttct gcactatctg
    32161 ttccacgacc taccaagcga tcttgcaatt catccaaatc tggtggtgtc aggaagataa
    32221 agacagcatc tggaaccttt ttcttgacct gaagagcacc ctgaacttca atttcaagga
    32281 aaacatcgat tcccttgtcc aaggtttcat tgacataggt cagaggagtt ccatagtagt
    32341 tgccgacata ttctgcgtat tccaacatct gtccttgacg aatcagctct tcaaattctt
    32401 cacgagtacg gaagaaatag tcaacaccgt ccacttctcc aggacgttgt gcgcgtgtcg
    32461 tcatcgatac agaatattga aattggtttt cagaactctc aaaaatctct cttctaaccg
    32521 ttccttttcc aacccctgaa ggaccagaaa aaacgattag taagcctcgg tctgccattg
    32581 tgtctccttt tagtcaatct gtgaaataac atttctctag aataatggca aaaagccaga
    32641 ttatccttta cagtctttct atctagtgta acaaaaaagc agtaattttt caactgctct
    32701 ttcttattta tttagcataa tctactgcac gaagctcgcg aatcacggtt accttgatat
    32761 ttcctggata atcgagattg ttttcaattt tcttacgaac tttgtgagcc aagattgtga
    32821 ctttgtcgtc cttgattttt cctggattga ccatgatacg aatttcacgt cctgcttgaa
    32881 gggcaaagct agtttgcact ccttcaaagc cgttagcaat ttcttccaaa tcatggagac
    32941 gcttgatgta gctttcaaga gactcactac gagcacctgg acgggctgcg ctcaaggcat
    33001 ctgctgcagc gacgataact gctatcacgc tctcagcttc aacatctccg tggtgactag
    33061 caatcgtatt caccacaact gggggttcct tgtacttacg ggccaattcc ataccgattt
    33121 caacgtggct accttcaacc tcatggtcaa tggctttccc gatatcgtga aggaatccag
    33181 cacgacgggc aagagccgca ttttcaccaa gttcgctcgc catgatacca gccaacttag
    33241 caacctcaat cgaatggcgc aaaacatttt gtccatatga agtacggaac tgcaaacgtc
    33301 ccataatctt catcaagtct ggatgaaggt ttggcgcacc aatttcatag gcagcagcct
    33361 caccgtattc acgaatctta ttgtcaatct cttgacggtt tttctcaacc aactcttcga
    33421 tacgagctgg atgtatacga ccatctttga gcaacatttc catagtcata cgggcaatct
    33481 cacgacgaat cggatcaaat cctgacaagg tcaccacttc tggtgtatcg tcgataatca
    33541 catcgacccc tgtcaaactt tcaaaggtac gaatgttacg accttcacga ccaataatgc
    33601 gtcccttcat agtatcgtct ggcagatgaa ctgttgagtt tgttgactcc gctacatatt
    33661 caccagcgat acgttgcata gcttgaacca agatgtcctt ggccattttg tcagaacgtt
    33721 ccttgacctc ttgctcagct tcgcgaatgc gactggcaat ctccctggtc aagttttcct
    33781 ctgtctgagc caagataata tctcgtgctt ctgcctgaga cagagcacca atacgctcta
    33841 gttctgcttc tttttgtctt tcgacttcct ctaattgctc ttcacgcgca tcaaggtttt
    33901 tcgctctatc agaaatactt tgttcttttt gttcaagtgt ttgttcttta ctcgtcaaat
    33961 tgtcgtcctt acggtcaagg ctagtagctc tctctgtcaa acgactttcg atttgtttga
    34021 gttcttgacg ttctgatttg aattcagcgt ccacttcttc acggtatttt ctggcttctt
    34081 ctttggcctc caatagtgct tcttttttaa gagacttgct ttcacgtttg gcttcattaa
    34141 caagtaaatc cgcttcacgc tcagcttgtc cacgtaaatt agttgcttct tgttcagcat
    34201 ttaaaagcat caactctgca gcttcctgag atgatttcat cttagctgag atgctgacat
    34261 atccaatgac taaaccaatg atgacggcaa aaacagcaat cgcaagcgac atgatttcca
    34321 tgtttttacc tcattttatt gttattccga atgacataca ttcttttaca ttctaccata
    34381 aaaaagtgat tttcacaaac ctaaaataga atatgttttg gggaatttgg aacacatttg
    34441 caaaaataaa cttgttgttt agaaatagta gtttagtaga gacttgagaa aaagcctact
    34501 ttacagtaga cttcctaatg attatgcaat acaagaagtt tgtttctaac aacagcaaga
    34561 tttcactcag gtattctctg taaatgagac tagtgtcctg cgcgaatttt atccattcct
    34621 cgcaaaacct tgtctgataa ctccttattt tgggcgattc tcagggtttc ctgaatactg
    34681 tcccattcgc tctttgaaag aactacaatg tcctcatctg gatttttatt gaccaccgtc
    34741 aaaggctcaa attcatcatt taccttcttc atgtagtcct ttaaatgatt tcggaatgtt
    34801 gagtaaagga ctgcttccat aaccatacct cgttttagct cttttccact attatacaca
    34861 aaaagaaaga aattgtcagg aacttgtaca agattttctt ttctatctat ttatactcaa
    34921 tgaaaatcaa agagcaaact aggaaactag ccgcaggctg tacttgagta cggcaaggcg
    34981 acgttgacgc gatttgaatt tgattttcga agagtattat tcgtaaaaaa tctcaaaaag
    35041 cctacctttt agtagactta gtttgtttct attctaatcg gcactcttcc aaaattttgc
    35101 tctgctatac ttggatttcc tagttggtaa atctggtctg ctttttgggt catagcatcc
    35161 caaggttctt tgccaattcg gctgactaga ctgacctgac ctttcaaaga cttgagatgt
    35221 tgcctacctt tttcagtaaa tccaaggaca tgaatgactt ctggcaagac attttctcta
    35281 gcctgcatca aaatataggt caataggcgt ctgacacgcg ccttggtgta acgtttggta
    35341 gtcactaact cgaccaattc ttccacagac tgggctgttt taatagcttc tttaatgcgc
    35401 acagccattt cttgattgac ctgatagatg gtggttaggt cgggatttga caagatttga
    35461 tagcggagca agggaaaata gtcttcccag atcaccttac tggcctgctc aaatagggca
    35521 acagaaggca taaaacgttc taagaaatct tggtccttct gatgttgacg gagggctgtc
    35581 gccgaggcaa agtccacatc tttattcaca gaatggtaac ctgccccctg acgctgaatc
    35641 ggatgcagct tgatatttcg tcctgcaacc gcctttgcat aggccagagc aagaacatga
    35701 ttgggggtat tacctgaaaa atcaagacca gcaaattcct tccacataga ttgggttttc
    35761 tggggatagg aaagggaatc aggcagattt tccacaaatt tctccatctc agcacctttc
    35821 tctgtgtata agtcagcgat tttctgataa tctcgaactt cctctgtccc aaaaactaga
    35881 ctatcaatgc ccaagcgatc caagatatcc acagctcctt gaccaaagaa atcagctgcc
    35941 tgaacactga ctaaaaaggg caattccact accaagtctg cgccattttc cagcgccatc
    36001 tgggcccttg tccacttatc cacaatagca ggctctccac gctgcatgaa attccctgac
    36061 atggcaacaa ttttcagtcc ctctgcctga tccagcaggt atttatggcc attatgaaaa
    36121 ggattgaact ccgcgataat acctgtgatg gtcatgctaa tctcctactt ctgcgccaca
    36181 aaaaaccaac gggtgctagt ttctgttggt tccttatcct caaagtctgc atagagtttg
    36241 aaggacttga atccagcctg ttccagtaag atatcatagg tcaagatctc ataggtcctc
    36301 tcctcatgta cttcatcgtg gcgactaaag gaaccgtcag cctccttgat aaagaaagtc
    36361 agctcatgca cgatggagtg aggagcttcg tcctcatatg tatcccaaag catggcaaaa
    36421 tcttccgcat tttcatggta ggaatagcca gggaatactt catctgtctg gtaggtcgag
    36481 tgcacgtcaa agatgaaaac tccctcttca ttcagcgcat tgtacacgtc cttaaagacg
    36541 tcccctactt ccacctcatc ctgcatatag cagatagagt ccgaataaca cgtgacaaaa
    36601 tcgtatttcc ctgccttgga caaattcagc atattacctt ctataaaagc aatcttttgc
    36661 ttggctgaag ttgctctctt ctccgcaatc ttcaacatat ccgcactcaa gtcaagtcca
    36721 gtcacatcaa aaccagcctg agagaagcgc actgattgaa ttcctgtccc acaagccaat
    36781 tccaagagtt tctttctctc cttggtctta ggcaaatgac gcagagaaaa attcgtccat
    36841 ttgtcgtata aactatcgtc catgaccgca tcatagaccg ccgcaaaggt ttcataagtc
    36901 gccataatca tgataccaag agctccatgg taaacaccac tagcccttta cctttctatc
    36961 aatttttcta aaataagcaa agaaacccag ttgattacaa ctgagttcat cttctaagca
    37021 agagcttctg aaatatctac tgaattcgcc tcatgccata acttctctag attataatgg
    37081 gcacgcattt cttctgaaaa gatatgcacg acaacagcac cgaggtccag taagacccag
    37141 cctccagctg catcgccttc gacatggcta cctttaaagc ctgcttgagc tactttttca
    37201 cggatattag ctgcgatagc gtccaactga cggctattca ttgagctagt gatgacaaag
    37261 tagtccgtca cactagtcaa atcttgtaca tcaagtgcga ggatatcctc cgcacgtttc
    37321 tcatcagccg ctttcacgac tagttctagt aattcttttt cgttcattta atcctctttt
    37381 tagaaaatat gtttgtaatc taggacatct gcaaagcgct cctcccaaat gtcctcataa
    37441 aattcattaa tcgtttctgc tggaatgtca tccccatcaa aggttgtgac agcaccttct
    37501 ggaacaataa gctgatagcc atattcaaag gcaaccttga cagaggtatc cacacaatat
    37561 tctgtctgca taccacataa aactaatttt tcaatcccct gcttatccaa gtattctttt
    37621 aagccagttt ctttgaaaat actgttatat ttcttctgaa agaccttttc agcaggtttt
    37681 cgatttaaaa gcgcagataa ctgccaatct tctgatgttt gagcttcaga gttctcaata
    37741 tgttgaacat agataatttc aatattcttg cttctagcct ggttttgtaa ataagaaatt
    37801 ttttccaata gactttttgt ctggaaccca gtttctacta aaacattctg aacatcaatg
    37861 attataaaag ccatcttcat ttagttctct ttcaaatagt gcacaaaggc gttataggtt
    37921 tcaagggttt ggggatagat ggggaatccc tgatgagcta gatactccac ggtacgagct
    37981 gtttcgtagg ccaccgcctt attgagcgat agacttgcaa tctcacgcgc cacatctact
    38041 ccaggaaagg ctcgattgtg ctcgatatag tctgctacat agacaacctt atctaggtct
    38101 gtcatctgac cagcaccgac tgtatggact tcaatggctc gcaggatttc tgaatcatgc
    38161 aaatccaaat cttcctgaat tttgtaaatt ccgaccatac catgccagac attattgccc
    38221 cagtttttga ggtcagggtc tagctggtaa cggtcaatca aggctagaaa ttcctgattt
    38281 gacaactttt tagcatagtc atgaagaaga cctgctagac ttgctttctc aacatctaca
    38341 ccaaagcgct gagctaattc catagcggca cgctccacac ccaagcaatg ggttaagcgt
    38401 ttttcaggta gaaactctac cattttttcc aacaaggcct cacgggagca gttgatatag
    38461 tcttgatagg acatcagtag agcccctcct tctcgatgta gtctagcact ggctgaggta
    38521 ggagaaagtt gggtttccga ccttgggcaa ggaagtcccg caccatgctg gacgagatat
    38581 ccatgagcgg tacgtccacc cagataactg gataggaagt ccctaccttg tagcgtggac
    38641 gctgaacccc cacaaactga accatgtcaa ccagttcatc aattcggtac cacttaggca
    38701 gatagtcaac catgtcggca ccgatgataa agtaataatc cgtatctgga ttcttctctg
    38761 tcaaaatctt catggtgtcg taggtgtagg aaataccctt gcgctccaac tcaatggttt
    38821 caatgactag gccgtcaatt ccctcaattg ccaactcaag catcttgaga cgatggtgtt
    38881 cagggatggt ttccttttta tcaacgtgag gaggttggta ttcaggcatg agaagaactt
    38941 gatccagtcc caactgttgc cgtacttgat ccgcaacaat gagatgggca ttgtgaacag
    39001 ggttaaaatt cccccctaaa atcccaactt gtttgcgttt tttctccttg atttctggct
    39061 ccaactctac cttggtaaag ggagtcaata gttcgattgt cataggctag tcccctttat
    39121 ttctctataa aaacagttat ttggagtttc ggtcttagat ttctttgact ttcttagaaa
    39181 tcttgcgatt ttctttcttg ctagattgtt taaacaaaat caagatgcgt cctatttttt
    39241 ggactgtatc cacaccgatt tcttcttcca aaatttcagc tacttcgtgg atgttttcat
    39301 ctgtgttttg taagagagta accttgatta attcacgcgc atcaagagct tgacggacgc
    39361 tggttttgat ttggtcgttg agtccatttt tcccgatttg gatgataggt ttgagggtgt
    39421 gtgcctggct gttgaggaag gcacgttgtt ttgatgttaa tgacataaat ttcttccttg
    39481 tttttggata gttattttag gtggtgaggg acggtcggaa ctaattttcc aaagatttca
    39541 tctttgaaaa atggatttcc tgacctcaca attgagcctt ggtctcaatt gtgccccttg
    39601 ccaatctaca gattggcaat cacaccacgg caataactat cgctatatga gctcactttg
    39661 ttcgctcagc gattttgttt taaataattg cttttcgtgt gacgacggcg acgccttctg
    39721 gtgcccagac ggcgactttt gctgtgcctg ttacacgaat ccatcctagg cctgagatga
    39781 ctaggtctgt cttatcttta atggtaaaga catgctggac tagccttggg aaatcttctt
    39841 tttccttgct atttggtggt gtcagaagag ttcccaggtg cttatcgtag aaagcactag
    39901 ctccttcaag cttgctacga tggagtttga gttcattatc aaagaaagca gtaaatcctt
    39961 gcttttctcc tgctataaag tcaaagcgtc ccaaaccacc taaaaatagg gtttgctcag
    40021 gattaagctg ataggtctta ggcttgattt cctttttagg actgacatac ttgaggtttt
    40081 tggccgtcaa gtagtgagcc atctggtggc ggtggataat tcccggcgta tcgtaaatat
    40141 aagatccgtc gtcaagcgga atctctattt tgtccaaggt tgtccctggg aagcgtgaag
    40201 tagtgatgac attctgatca cccgtgattt cttggataat agcattgatt agagttgatt
    40261 ttccaacgtt ggtcacaccg accacataga catcgcggcc cttacggtag tgttcaatct
    40321 tatcaatgac ttccttaatg gcatgtttat tttgtgctga agttaggacc acatcgactg
    40381 gacgaagacc ttcttcacgg gcacgtttca tgagccactg gctaatctta ccagacttaa
    40441 ctgacttagg aaggatatct tttttatttc ctaccaagag gacatcattg cccgagacga
    40501 aacgtggtaa acctgggatg acagatccat taaaatcaaa gatatcaatg acattgacca
    40561 ctaaggcatt actgtctccc acctcgtgca agagcttgag gaaatcatcg ttcgtcaact
    40621 ggacatctgt gatttcattg tagtggcgga gacggaaaca gcgttggcaa tagacttcgc
    40681 cagtctccaa acctttttca agtgccgact ggggggtaaa accaagacca gctttatctg
    40741 tcgtctgaat ggttgctcca caaccaatac agagaatttc ttccatagtt aaattccttt
    40801 tttatatgta atcggtccgt acttttcagt gatttttctc ataacacgac gctcacgagt
    40861 tcggttaatc tgcgttttga ttgagtcatg ttggaccaag ggtttgacta aaattgaccg
    40921 aatccctgca cggtgggctg ctcgtatatc tgtcatgagc tggtcgccaa ccatgaccac
    40981 ttcctttttg tcatagtgga attccttcat agcacggtca ataccaaatg tgaagggctt
    41041 caaggcccag taaacgtaat caatcccaaa tttctcaact gctcgttgaa cgcgtttttt
    41101 ggtgttattt gacactacga taatgccaat acccgcgtcc cgaaggtcat gtagccattg
    41161 cttcatctct ggcgttccat cagggttgtt ccaagcaatg agggtattat ccaaatcgac
    41221 caaaacagcc ttgattccct gcgcctgcag gcttgggact gtcagatcat agactgcttc
    41281 cacagcaaaa tctggtatat aattttcaat cgccattctg gctccttttc ttaacttttt
    41341 ttcgcaattt tccttagtaa caaggataaa acaatccaca aacctgcact agccaaactg
    41401 atatagagcc aagcatgggg ctcatctgtt aaaggtaagg gaacattcat tccgaaaaag
    41461 cctgtcacga ctgccaaaac agctagcaag actgaaatga tagtcaaggt tgtcaaattg
    41521 tcattcagat tattgtttag aatattgttg taagaggctg aaagctgctg taaaatctga
    41581 gagattaggt ctgtcatgga taccagctga tgagcctcaa tcatggcatc atcaaactgt
    41641 tctctctcaa tctcatcaaa actacgatac aaggcatgac cttgaatatg ctctaacaaa
    41701 atccgatttt gtttggcagc tgccgtcaga taaaccatac cagtctccaa atcagacagg
    41761 acaaagaggt ttttcttggt agttcgctgg cgcaagaggt cattgacctc atccctactc
    41821 ttgtccatct gctcaatgac aggatagtag gcattgctga taatttccag actggcaaag
    41881 agaaacttat aaatcgaaag cgtgtcatgg ttctccagat aacgagtcat ctgttcaatg
    41941 acataggcgt tcttggtatt actaatggta atcaggcgac gatgctcgac aataaaggtc
    42001 atgggaaaag tctcatagta ggccttgtcc ttttttacgt ctaagacatt atagataaag
    42061 gtaaccgtct cactttcacg gtggtagtcc atgtgggcgc gctcgtttct atccagtgcg
    42121 tattcaatgg tttccttgtc caaaccgtaa atttcagaaa ggtcttctag tttattcaac
    42181 tttcctaggt ctaggtctat ccaggtacaa ccattgccca actgcttttc taaaaccatc
    42241 ttttctcctt attaaactcc ctctattgta ccacaaatta cttaaaataa caggtctagt
    42301 ctgtgcgtga gaaattgcta acaactgtga tatttcggtt agggacaaag tgaagggctt
    42361 gctcctcgct acgaagctgt gtcgtacgaa ttcccacact gacaacctta cccgatacag
    42421 taatcggtcc atttgtcaga acgacctcat ctcccacatc cagttgacgt tcaaagagga
    42481 tgaaaaagcc attgatgaca tcagacagaa agccttgggc tcccatacca atcgctaccc
    42541 cagcaatacc agctccagcc agcaaactag aaactggcaa acctaaaatc gacaaaatgc
    42601 agtagagtaa aaagaaatat agcgtataat taaacacatt ttctagtaaa cgtgagatgg
    42661 ttttttggcg tccaacatca tgacgagaca tttttagaga aggtttgaca attctctgca
    42721 ccatggtatg aagcattttt ttagcaatat aaaatacaat caaaagcagt aaaagagaaa
    42781 tgaccttggt tagaatattc tcgataatgg ttgtcacatc tagcttttca atataagcct
    42841 gaataaattt ttgcatataa aactccttta tttcattata ccatattttc atcagtctca
    42901 ttctccataa atattcaaaa aatagacaga aaattcttga ttttgtctat catttatact
    42961 ataatcataa tcactacaca aaaaggagat tattatgaaa agaatcattc atgcttggaa
    43021 taaggcaagc cttgtcaagc gtatcttgat tggtatgctt tgtggggaat cctaggactg
    43081 acccttccta atctctcagg gattgggcta ctcggggatt tattcgttgg aggtctaaaa
    43141 gctgttgctc ctatcctagt ctttgccctc gttgccaatg ccctttccca acatcaaaag
    43201 ggacaagata gcaatatgaa aactgttgtt ttcttgtata tcctatgata gggactttcg
    43261 ccgctgctct tgtagctgta ctagcaagtt tcatcgtccc tattgaaatt accctaaata
    43321 gtgccaatac tgaaattgca ccaccagatg ggattgggca ggtcctcagc aacctcttgc
    43381 tcaaactggt tgacagccca gtcaacgccc tgcttactgc taactatatt ggaatcttat
    43441 cttgggcagt catttttgga atcgctatga gagaagccag taaaaccagt aaaaatagta
    43501 aagaattgct aaaaactatc gctgacgtga cttctaaaat tgtcgaatgg atcatcaatc
    43561 tggctccatt tggaatcctt ggtcttgttt ttaaaaccat ttctgacaag ggagtcggaa
    43621 gccttgccaa ctacggtatt ttattggttc cattagtaac gactatgctt tttgttgccc
    43681 ctgtggtcaa ccctttgatt gccttcttct ttatgagacg caatccttac tctctagttt
    43741 ggaactgcct ccgtgtcagc ggtgtgacag cctttttcac tcgtagttct gcgactaaca
    43801 ttcctgtcaa catgaaactc tgccatgacc ttggactcaa cccagatacc tattctgttt
    43861 ctatcccact cggttctact atcaatatgg ctggagtagc gattaccatt aacgttttga
    43921 cccttgttac agttaacact cttggaattc ctgttgactt tgccacagcc tttgtcctca
    43981 gtgtggtagc agctatctca gcctgtggtg cttcaggtat tgccggaggt tccctccttc
    44041 ttatcccagt tgcttgtagc cttttcggta tttctaacga tattgccata caagttgttg
    44101 gggttggttt tgtgattggt gtcatctaag aatcatgtga aacagccctt aactcttcta
    44161 cagatgtcct ctttaccgcc gttgccgaat acgcagcaac ccgtaaaaaa taactcatca
    44221 aggcaagcct gctcatgtct tgtcttttac gcttttattc taacttatta ggaaattctt
    44281 atgtctatta gccaacgtac gaccaagctc atcttagcta cctgtcttgc ctgcctgctt
    44341 gcttattttc tcaatctttc gtcagcagtt tcggctggaa ttatcgctct cttgagccta
    44401 tctgatacgc gtagaagtac tttaaaactg gctcgcaatc gtcttttttc tatgcttcta
    44461 gctctggcta tcggtgttct agcttttcac ttgagcggat ttcatatctg gagtctcggc
    44521 ctctatctgg ccttctacgt tcctttagcc tacaagatgg gctgggaaat tggcatcaca
    44581 ccaagcactg ttttggttag ccatctcttg gttcaagagt caacctctcc agaccttcta
    44641 gtcaatgaat tccttctctt tgctattggt acaggatttg ccttgcttgt taatctctat
    44701 atgccttcac gagaagagga aatccagcac taccacacgc tggtggaaga aaagttaaaa
    44761 gatatcctcc agcgcttcaa atactattta tccagaggag acggacgcaa ccgagcacag
    44821 ctggtagcag aattagacac gcttttgaaa gaagccctca gactggtcta tttggatcac
    44881 tctgaccacc tctttcacca gaccgactac catatccact actttgagat gagacaacga
    44941 caaagtcgta tcctgagaaa catggcccaa cagattaaca cttgtcacct tgccgccagt
    45001 gaaagcctga tcttagcgca actcttttca aaaattgcag gtcaactgag ccagaccaat
    45061 cctgcttctg atttgctaga tgaaattgaa cgttatctgg aagtcttccg gaaccgcagt
    45121 ctgcccaaga caagagaaga atttgaaacc cgcgccaccc ttcttcaact cctacgtgaa
    45181 gccaaaacct tcatccaagt aaaagttgat ttttaccaaa aatatagaca gtaatactct
    45241 tcaaaccacg tcagcgtcgc cttgctgtat atatgttact gacttcgtca gttctatcca
    45301 caacctcaaa acggtgtttt gagcagcctg cggctagctt cctagtttgc tctttgattt
    45361 tcattgagta taaaaaagaa aacttcagac caatccacaa aaggtgaata tctgaagttt
    45421 tcttttattt ataagtaatc accataaaga ttaatagtag aacaaataaa gccaaactca
    45481 ccaataaagt gagcaccttg accaaggtgt tgctctgcca gtagcttggt ttaccaatat
    45541 tactagtggc atccatggaa aatagttgat tttgacgggg ttgtatagtt accaatacaa
    45601 tcaaagcaag agataggata atagctaaaa caattagtat ttcaatcata gatctacctc
    45661 aaaattccca gcaaagtaaa gagcaaacca atcagaatca tcaaacccag taaaagtgaa
    45721 aaagtcttac taatcttttc ccctcgggtt tctttttcct tcttgatggg tttttgtttc
    45781 aactcttcca tgcggccttc aacgtctttg taaaataaat cttcctctga catgttagcc
    45841 tcctaaaaca gtttgcatgg tttcctgata tctcaccaag tcaacataat ttgcatgttg
    45901 gccttgtttg ccaagtgcct gacgcatttg atcaacatct gaaagggcca atttaatggt
    45961 ctcaaccaaa gcagcaactt cactactttc aaatagatgg tctggagcga tataaagtct
    46021 attgtgcacc gtctgattaa agccaagaat caagagattg tgctcaaagg cctgacgcac
    46081 tgcctgtagt aactcattac tgtggtttat atccaagtaa atatccgaca gttgatacag
    46141 ctcctgaatc ttctgtggac tagcattctg gtaaaggacc acattaggat agcgaagcat
    46201 gtctaagagc ttagaagaca tctctgtcac cgctgcaata cggaaagtga cagcaggcaa
    46261 ggctcctgcg attgcttcta cttgctcaat ctgatctgaa ttggtcaaga ttaaggcatc
    46321 tcgtcttagg aaattatcac gtttgaactg gtaatgataa cccaagtgca caaactgatc
    46381 atggtatttc tcgtcagtta actctaaagc gcgctcataa gtcgccttat ttggaatgat
    46441 gatcttctta gtacgcacat tatcactttc caaaatcaac tgcatattac ctggaatggc
    46501 atcatagaga ggttcctgcc ataccaagac atccgagcca gatttatctg gatgatggaa
    46561 ggaaaccaag aaaggagtcg ctagagtatt aaagataagc tgactggtat ctatttccaa
    46621 atcttgcaaa aagaaggtga taaattcaac tttatttgca aagtaacgca tggactgacc
    46681 aggcaaagtc aataagatat cacccgtcac atggttttcc agtaaaactt gttggccatt
    46741 gacatcttgg taaactgtca taatcggctc gctatctgcg ctataagtgg ttttagcaaa
    46801 gcaagcacca aagcgattgt agtggtcaac ctgacgtact cgaccttcta ggtctttcca
    46861 gtctacctgt ttaaccaagc gagcctgcat tccatcaaca taatgaatga cagccctctc
    46921 ctgcgtcaca tcttcaatac aagcagactg attatctcct aaaatttccc aaaaatctga
    46981 aacgggaact tggttaaaat agagaggttt tccatcctcg taacctagat aataggtaaa
    47041 aggagaaagc agaccatcag gcagaaaacc atctgcatcg atgaccactc caagttgaga
    47101 aagaccagta gcgactagac tttcatgtaa atctcgactt tcttgactgt aactatcata
    47161 aagttcaatc atggagcacc tcctctactg ttttcttcca cttttctaaa atttctttgg
    47221 tcaagaagcc ttctgcaatt tgataagaat aggcacgcat agcttccaaa cgattttctt
    47281 gatacaattg acaaatctta gcggcataag cttgcttgat ttggtcttct acatggtcag
    47341 atgaacttgg aatcaaataa ccattttgcc catcctctat aaaggtctga ttaccataag
    47401 gcacatcaaa accaattaga ggtagacctg aaccaatagc ttccatcaag gtcagaccaa
    47461 atccttcgct ggtagaagcc gttaagtaga cctcatactg gctataaatc tgcgaaagtt
    47521 ccgcatgccc cttgagttgg atatagtcct ctgcctgatg atttgcaata atttctctaa
    47581 gcagagaatc ttctccacca ctaccataga tatcaaaggt tagttccggt aactccttat
    47641 gagcttcaat cacagctttc acaagccaat caatgtgctt ttctttggca agacgtgaag
    47701 ccgtaatcaa tgaaaatggt ttgcgccctt gacttgaatc tgtcaaggaa tcaatactgc
    47761 ctacaggaat ggtaacaatc tttggctgat gctgagtata tttggcaaat tgctcttgta
    47821 gaacttcatt ttgtctatca gtagacacga taaagaagtc aaccttatct gcattggtaa
    47881 actgatagtc ataatagtta ttccaaagga tatagtcctc atttgtagca ttttcactat
    47941 aatgctccgc atgaacaact accgctagat gtgctgtctg tgcttcctca aacacaacct
    48001 gtccaatacc tgtctcccta tccagaataa ccaaatcaga cttgttcaaa ttcaaagatt
    48061 tcataaaggc acgcacaaaa gcttgctttc catagaaaat cttatccttg aaatgataaa
    48121 cttcttcctt cccttgattc atcaagatat catagactgg agtcccgtct tcattgtaaa
    48181 aagttcgttg gtataagact gcaacattgt ccttgggagc aaaatactcg ctacaataac
    48241 gcgtataaga aaagtaatcc ttccgaatca ggtttccctt aaaaacatac tcggcatgtt
    48301 gaaccaagtc cttgtcctca tccaccaaat aacaggttac aaacttatct tggtcaaaaa
    48361 agaagacacg taaaaccttg ccattttttt ctctgtgact ttcttcacca ccaaagtaag
    48421 ccaagacatc atccactgtc acgctagtag gcgcaatttt gatgtctgtg aaatgattat
    48481 aaagccagat aacctgatta tcatcaaaac caatattggc tgttaagtgc tgaatattat
    48541 cggctaaaat catatctgta aagataaact tagaggacag atttaatttc cgaaaaacac
    48601 cagcacgata ggcttgagcg tattcaacac cgctactagc ccaaccaatt cctaaattta
    48661 tattgtaaat tgtcatattt tctcctctta tggaaaatga gtcacgattt caccttttgg
    48721 agtgacctca accagcccca tcaggagatt acgcaccata tccgcacgga tttgttcttt
    48781 catagcttca aagcccgcgt aggcttcttg atagtactct acgattggat ttttctgact
    48841 agcagattga ccaccgatag ccatggatag ctgttgtaga tagtctacct gctctatcca
    48901 gttgtcatca atggctttaa gcagtgaaag tcgtaaaaac tgttcatata agtcatgttg
    48961 attaagtaat tctttctttt cagaaagttc tttatcaatc acctgcttca taaagctacg
    49021 aactgcagtt ttgtcagtta catctatata atctggaacc tctttaacat gaaaactaat
    49081 attggtcaca ataaagtgaa acagtaattc acgactagca tagtgatcag ccgctacctc
    49141 ttctgtatat ctctcaatga tatccacaac aacatcctct aagtcacgag aaccatctat
    49201 tagacgatta cgctccttgt aaatcatatc ccgttgaata ttcatacttt cagcatattc
    49261 tagagtctga cgacgtgccg aacggccagc actatcacta gcatgttgag ccttttcgac
    49321 tagtttccgg tatttacgac ctttcaatac ttccggttga gtcatatctt gaacctgata
    49381 gtctttgtac tttttatgca cccaagatgg accaaatttc ttgataacat catcctctaa
    49441 ggatacaaaa aatttactca taccaggatc tccctgacga ccagaacggc cacgaatttg
    49501 taggtcgatc cgctgacttt ccatccgctc agtcccaata acaatcaagc ccccaagctc
    49561 tgcgactcct ttaccaagct tgatatccgt accacgtcct gccatagagg tagccactgt
    49621 cacagccccc atctgacctg actcggagat aatctgagcc tcacgcgccg cattattagc
    49681 atttaaaaca ttatgggcaa ttccctctct gagcaagagt gacgaataaa gttgagacat
    49741 ttcaactgag cctacaaaaa cgagtaaagg atttccctta gcatggtatt ccttgatgta
    49801 ctccaaggat gcatacactt tttcaggtaa agtgatatat agattatctg gatagtcaat
    49861 ccgttgtctc ggacgattgg ttggaatgcg tactacagac atattgtaag tttcaataaa
    49921 ctctttttcc gcgaccttac ctgtccctgt cataccagat attttattaa acatcttaaa
    49981 aagactctga taggtgatcg aggccatagc ccgcgtctca ggagataatt tgacatgttc
    50041 cttggcttca atagcctgat ggagacctcc ttgaagttta gtcatttcca ttagacgccc
    50101 tgttccctta tcaaccagta ccatctcatt tccacgaatg atatagtcct tatctttagt
    50161 aaagagctta tgagctcgaa tcgcataaac caaatgacga gcaaaagacg catgctcttc
    50221 cttgtataaa ttatcaatcc ctaggaaatt ctcagcagac ttggccccct tagtagtgag
    50281 ccaaacctcc tctttctcct ctttaaagat ataatcctct ccttcgacca aggttgttac
    50341 aagtgtatca atgatcgcat agtaattaga ctgaacacga ggagaacccg caataatcag
    50401 aggagtttgt gcactatcaa gcaagatatc atcaatttca tcaataatca catagttaaa
    50461 cggtcgtaaa aacttacctt cttcattcga ggctaggtta tcatttagat aatcaaaacc
    50521 taaattacta ttggttgtgt agatgatatc cgaagcatag ataagcttct tttcttcagc
    50581 tttcatctcc ttctttggat cttccgtaaa tggtacacca atggtcaatc ctagaaaacg
    50641 ataaacttgg cccatttcct cggcatcacg ctttgataaa tactcattag gagtcacaac
    50701 catcactcct tctcctgaaa aagcgttcaa atagacaggc atggtagctg tcaaggtctt
    50761 accttccccc gtattcatct cagcaacatt tccatagtgc atgacaatag ctcccatgac
    50821 ttgaacatca taggggaaca tccctaaaat ccgcttatct gcttcacgca ccacagcaaa
    50881 agcttcaacc aaaatatcgt ctagactttc tccctcggaa agacgctgac gaaactctac
    50941 tgttttagct actaattctt gatccaaaag agaggacatc ttgcctttca gggcattaat
    51001 ctgctttaaa atctttttca ctttcctaag ctggaaatct tgacctaaac gtctaaacac
    51061 ttctgatctc cttgatagaa aaatgataaa aagttaagga ctcaaatcca gcacttaaaa
    51121 gagaaacttg ataagtataa ctatcttctg gataagtaaa tatgaaatct ttcgcttttt
    51181 ctaccttttt ttctaaaata tcaccatagc ggtcaaaaaa agttatcttg gtataaactc
    51241 cattttcagg ctggcaatca aaaaccagtg atagttgata ctcctgcttt ctttttaata
    51301 agggaagctg aggttgggtt cgtgcagcct ggtaattgac actagaaaac caagtcttta
    51361 gaatctcacc agatggcaat agaggattat acagacgaac acttttgtca aggtaataag
    51421 atacagttgt tccatacata taagtcccac caacttctcc ccaataaata gactgtctct
    51481 gtgtaataat catcttttct cccttccaaa accagtctct aagaccattc tataaaagtg
    51541 caaaaaccaa gaaatattgg tatctgtatc atcattgtgt cgtccagcag ttcctttaga
    51601 taaaatcttc gcacctgtat tacacagata agacactaat tgttcatagg cttgtggatc
    51661 catttcttca tctttcatat aggataaacc aaaggttgtc tttgaaaaat ttgcttgttt
    51721 aaaaattttc caaaaacgct gatccaactc cgtcatatct tgagaacttg tcccacctgt
    51781 atgatgaatt aaacaatcaa aagctaagtt agagacaccc ggtgcgtcca aacgtccacg
    51841 actagctata gttcctaaat tagccaaggg cttaccaact atgatggcat ggggttcaaa
    51901 agaagcacca taatagagag ccggaaacgt tcccatagaa agacctgata aaatcaaatc
    51961 cttatgatca aagcctaaat aatcaagata gtgagtgatc gtatccttta cttttccctc
    52021 tagctcatcc gttccgagat aaaaagctcc cccctctaaa cgtggatcag aaaataaaat
    52081 gaagggacat ccaagagttt tcatcataaa gtaaccctcg aatccttctg caggtcgata
    52141 acctgcaaaa tagacagtca aaggcggttt aaaatcacct ggatggaaga aatagtttat
    52201 ttcatcacgc ttggaatcat gtaggatatt tccaccaagt acaaacttac caaattgttt
    52261 tcgactccat cgttggtgaa gattacctag tttgatagtt ccacgacctc ttgcttcaac
    52321 agatatcgag agaaagtagt ctccgtctcg actatccata aaaagtgctt gctccaagtc
    52381 tttttcagat actattactt cttcaaagaa atcatcaaca gacccactcc acattttacg
    52441 gataaccaaa cgaaagtcac aattaccttc cttctcatat tcaagccaca actcaatagg
    52501 gagtgttttt tgcaccataa tattataagc ccaataggca agctgggcaa aatcttgccc
    52561 aaactcacct tccaaactga cataatccaa tccttgataa gaaatagctc ctgtaaaatt
    52621 tggattgact tgtatcgtcg gaggaaagag tttatcacca tacccaccgc caaaaagaga
    52681 tttacttaaa tcattgatta attgttgggg acttaaaaaa tcaattgctt gtgcacatcg
    52741 tttttttaga aaatccacaa cctctctatc atttatttgt agattctggt tatagaacaa
    52801 agtataaggt tcaaaatatt ttacatagga aaataagtct ctggaatact gaccatcttc
    52861 tattaaaact gcatgaaaac ggttaatatc ttctttttcg attatttcac gaagggcttt
    52921 tgatgagttt gggtaaaaat aataccaact catattttca ggtatgtcat agtgattttc
    52981 ccaattggca agtcctatct gtaaaatatt aagttccttt gacattttta acctcctcta
    53041 tccatttctc taattttcca agaaattgtt gtcctgtgtg ctccttaatc ttatcaattg
    53101 aatatatcaa ggactcattc cactccttca acctatctgt gtaataatgt gcagccttag
    53161 aaaattctgt aacatctgct aacaaataac cattttttaa atgttccaca tagacggttt
    53221 caactaggtt gatttgagga attcctgcac taatcccagc aatctgtgtg tagagatgag
    53281 gatgtctatt taaatccaca atcaaacgga caaattctag tgtttttatc aaatctaact
    53341 catcattcaa gttaacaaac tgtaagcgta agtcctggtg ttgattttct tccagaggat
    53401 tttctgcatc accataatca atcgcctttc ccaggttttc ggattgaatg ttttcttgga
    53461 tgaaagactc aacaatccct tcaaccacat tcatttgctc ctgactagca gcaaaggctc
    53521 caaaaatcac ctcagtatcc ttattttcag cgacaaagga caagacttga agcagagctt
    53581 gattatcaat cccctgctca aaatccagtt gaaaataaat gatggattct ttcttagttt
    53641 ggcttcgtcc caatcgtaat cgggtgtcaa aagatgataa atgataacat tgatgcattc
    53701 gttcaggata caactcctgc aacaatcgta aactatcctc tctatccacc aaaatcaaat
    53761 ccgatttttc aaaagttaca tctaaatccc taaaggtatc ttgaggatta cgtccaatga
    53821 acagactcaa cagtttagga ttagtactag gtaaacgatc tagtaccaac tggtcatgat
    53881 gagaatgaga aggaagcata aaaatatcct gatccttcac atacgtttgc agataattct
    53941 caaaaaattc tgccaccaga tctcccatat tttgataggt aagcatttta aagcgataac
    54001 ccaaaattgg attgacttct acctgtcctc cttcttttaa acgctctcta aattgccaaa
    54061 ctcccttagg attcaaatat tcttgatagg ctgcttgccc atcttcaaaa aagataatgc
    54121 tcgatacaaa ccctcgatca tccatgatat ggtgcatatg tatttgacca ttcggttcaa
    54181 aatactgtat atcactgatg aagccttcaa ctccatgttc aaccttagca aatttcttcc
    54241 catttttttg aacgataatc gtaaagggac tataaataaa ttcacagtca tcatcccact
    54301 caatatctct aatgcttaaa acttgggtat ggagattatg aaaatcttgc ataacatcaa
    54361 aaacggaata agtatccgtt tctaacacac catgtctata taaaaaataa cgtagatgag
    54421 gctggtaagc taatactaat agacgagaat ctatatcttg ctcttgaaag agccggatct
    54481 ggtgaaaggt atcatcaaac tctagacgaa aatgagaaaa ataccatgga gtgatatctg
    54541 catgccatgt tctttctgac ccataccaag ctggaataaa ataatacata aaagtctcct
    54601 aaatcaaggg tctataggta tcatttagcc ttaaagcctt gacctcgtct ctaatcgtaa
    54661 aaatcatgcc cccgaacatc ataaataagc ctggaatcat tgccaatcgt aataactttt
    54721 catcaaacaa aacaaaaagc atgggaccac ctgccataac cacattaaag agaccaccta
    54781 tgactgagaa acgaaggacc aatcgattaa taaatcgact agtatccgca cctggataaa
    54841 taccataaat gtattctcca gattttttca tacggtctgc aatctcttct ccattcatcg
    54901 taacaaaagc aaaaatgata ctaaataaaa ataagaccga aatataaaca tagacccaca
    54961 aaggctttcc aatcataaat tcctttgata aagccgctaa ccctgaatga ttagggaaaa
    55021 taaatcccaa caagatgaac aaataagctg gtacactaag aaaactcatc acatacatat
    55081 aaggcatccc acctgcagga ttcaacatga tttcgagata aaaatagcgt ttaaatcgat
    55141 tgtgtaagcc aattttatta acaggaacca aatagcgagc tcgatacata agggcaagta
    55201 aataagaaaa gacaagggtt aataaagcaa gtaacacaat aatccctgtt ggaatgtgta
    55261 ctgtctgaaa tgtttccaaa acatcctgag gaatatttaa aaccatactg gataggagaa
    55321 tgactataga acctccaatc cccatactcg catttaaatc tgacaaccaa acaagaaaaa
    55381 atgttcctgc tatcagcaat attgtattca ttagaacaac caatattgca gaataggagg
    55441 attgtactgg cagtctcaag ctaactgcca atgattgaat gacagctatc atcaaggtca
    55501 ggtacatttt acggcgatct tgtatttcta tagacgtaga tgttaaaccc aaccgtttag
    55561 aaaaagaaaa catctgccat aaaatcatag ctgacatcca aggggacaat ccaacagaaa
    55621 aaattgacaa acttcttaga tttccacctg ttagggcggc tgagaatgct agataggctg
    55681 ttgaacctcc taaaaaatct ttagtattta ggtcaacaaa agggagagta atacgacttc
    55741 ccaatacata gataaacagt agaaataagg taaatagtcc tttttttact gctattgacg
    55801 aataaatctt agtcataaaa cactcccctc accttcattg tttgtgatat ggtaaataac
    55861 aattctttta tttcaacttt taccatttct ttgttctgca tcaaaaaaca actttaatct
    55921 gaaacaaata tctttatatt cctcagtatc tgttaattga tggtattcta aagtttgctt
    55981 ataatctttt aaaagattga caaatcgaat acgcagaacg gagacatcca aaccagccaa
    56041 gacacaatcc gatattttct tagaaaacac ttcaacaata tctcttgccc aggaaagatc
    56101 aaattccgtt ctcatgatgc ttcctgaacg tcttctatac agatagagat tatcgtttat
    56161 aaagacgatt ttagaggcta aaagataaaa gcgatgcata gttgcttcat catcaaagcg
    56221 gcgaccattt gaaaagtgaa cttcattgaa taattctttt ttaatcaact taaatgtcgg
    56281 caatataaag gccgagctat tgaatttcca atctcctgct tgacggttca taatttcttg
    56341 tatagctaat tcttcgacgc aaaaatcttg ccctgttaca taaaaataaa aattcccgtc
    56401 actttcgtca taattatagt aattccctat aacaacatct gcatcctttt cttggacttg
    56461 ctgataaaga gtttcaatca tattttcttt tacgatatca tctgaatcaa caatcgtgat
    56521 gtactctccc ttagctacac taatccccat atttttaact tgtgctgccc ccccttattt
    56581 tcttgatgca atactcgcac acgattatct tgcatcataa aagcatcaca aatttcccca
    56641 gaattatccg tagaaccgtc atcaactaaa ataatttcta tattttgata ggtttgcttc
    56701 agaatatgct cgacacactc cactaaatat tttcccgtat tgtatatcgg taccacaaca
    56761 ctaattaatt cactcattac tctatctcta tattcttcat tctatccact aaatcatctg
    56821 gtctctccac agaaaaaata ccgtcataga gtccatcatc catactttta cgtgtgatat
    56881 caaaagcgaa gattttcttg ccactttctt gtgcccttgt aactacatta aaaacctctc
    56941 cacctgtatt aatatctaaa taaactatag aatcgtccaa tagccaatca attctactat
    57001 gtaatacatt ttgatatact gttacattcg tatactgtga tagagaggtc agctcctcag
    57061 aacaatcaca cggtgcagcc aaatgaaaat gccaatcagg taaccgttgt actaaatact
    57121 ctaaatgttt tatatctgca ctccatgtca caagcatcac ttgtttttta gactgattgc
    57181 ttctttcaaa ataatttaaa tcggaacgtt gaaaagcaat ctctgaccaa tccaaatctc
    57241 tataaaccca ccataattca cgtagtctag atatactata tgtattccaa ggtttatcat
    57301 gactagcata gtgaacaatt gtaggtggat tgtcatctag acgttcacat tcttgagcaa
    57361 ggtgataaat atcaacaccc gccatataat tatatgtttt atctaaggct agccaattat
    57421 cctcaaaata aatatttaaa atactctgat ccccaagatg aacaacttga ttctgctcgg
    57481 ccgctaattc caataaacta ttgacaatag aatgttcttt ccactttgca acatccatta
    57541 ataaaactcc agaattaaat ccagattttc gtccttcata ggcatagaca tcatcaacag
    57601 caccaattga atatcctttg agatctatct caaacaaagt agctagttcc ccagttacaa
    57661 tgatatcgga atccagatac aataccctat cagattcaac cacttctgtc gcaaaaaatc
    57721 taaagtaaga agcataattt atatgaggtc ctgttttata gctttcaaaa agttctttat
    57781 caatgtgtac actgcgaatt gtagaattca caacttccat ttttctcccc aataatttaa
    57841 accattcagg agctatatca ctgttgagaa tataaaaatc aacatctcta ttgtgataca
    57901 atacagactt tatagtcgtc tctaaaggaa taagataggc attatctgcc gctaatacta
    57961 ttgattttct catactgttc tctacctcat gtaagatctg attgctgcaa ccattttttt
    58021 cggaatggag cttggataga taccttcata tgaaatctca gaaagatttt cagagcaagt
    58081 attgtcgaaa gctatcattg gttttttgta cttaagcaca aactcatatg catcttctaa
    58141 ttttcgatca tgattcaaat ccaaatacaa atctgaagct attactattt gttccaataa
    58201 cattggtaag gaatttggat atacggtaac attaggaaaa cgcgttaaag ctagtagttc
    58261 atttgccata tttgtataag caacaatatg aaaatgaact tctggcaatt gctccgccaa
    58321 ataatcgatt ttctcgacac accaagaatt cgttaaatta acacattgca acttaaatat
    58381 ttgtgattta ctaggatact tcacactctt tgaaaaccat tcatttaaaa taacagacca
    58441 atccatcaaa gagtattccc accaaacttc tcttagacgt ccaacagaaa attgattcca
    58501 aggcttatcc tgagaaatat agtgtaaaat tagtggcagt ggttcgagcg gaatatcaaa
    58561 aatgaattga tgtttaaagg ctgccgcccc ataatcatat cctatttgaa aattatattg
    58621 atcttcaagg gaactatatt gatctttaaa caacatattc aaaattgact ggtctccttc
    58681 ttccacattc tcatgttctt tttctgttaa gtcaatcaat ttttgtcgaa tagtttcaga
    58741 tccccatttt ttgttgttaa tcaagagaac accagcattg aagccgactc ctgctccaaa
    58801 gcaagaacga gctgctgcca aataattttc acctaagtct aattcaaaca aatcggtcaa
    58861 atcaccagtc acaatcaaat cactatctag atagagaact ttatcttctg ttacaaaatc
    58921 tggaataaaa tagcgtgcaa atgtcatatg attgatatga ggtaatttat tagaccaatt
    58981 catttgaaac tgtgagccaa ttaacttgca gtcaatcaag tcgcccccca tctcttgtaa
    59041 atatattctt atttgactaa accattcctg aggaatgtcc tgatttagca gataaatttt
    59101 caaatgacta ttgtgtctac agagtgactt catcgccgtt tcgatttgtc gaatataagc
    59161 gtaatcacct gcaaatacta cagcgcgttt ggtatttctc attttaaatc cttatcattt
    59221 attttaaata gtctagttta atattcgtgc aacaatctga ctgttatagg tttcatcatc
    59281 aataaattca atatcttggt cgaaattatg ttctgcagta tgtttatgag aaaatttaac
    59341 cttagtttta gctcccattt tcatccattc atactctgag tcaatatggc ctacatccaa
    59401 aacttgatag cccatctggc atagattata actcagaact tttgctgtag gacccagcat
    59461 acataaaatc agtcttcctt cagcatgttt cataatttcc tcttgaatgt tatcgacaac
    59521 ggaataagca ttatgagatg gacaaataat ccttttcaca gatttgacct tattaaataa
    59581 atcatttcca accccagagc gagatgtaat cccctctaca atcagaatat ccctattctc
    59641 ccaaatactc tttagctttt caaattgtcc ttttgcctta ctcttatctt cataatcaat
    59701 gtatggacgc gagataaagg tagagccata ccatgaaccc ttacacaact ctttataaaa
    59761 atccatataa acattcatat gttctttcca gaatggtgta gcccaccaag taaagacaaa
    59821 acgatcgtca aaagcatcag gtaaacaaac cactaatttc tcgtcactct caagacccac
    59881 aatatgtttt aattggttag ctaactctag atcatgattt tgataaggta taggcaaacc
    59941 ccacatcaaa ttgacttctc cgtctccaaa acgaactaat gaggacttat ttttgataac
    60001 ataatccaga gtctgatcaa ttccgataac cttgattggc ttctctggtt ctcccaaagt
    60061 ctctcctttt atcaatgcat gaaatgcttg aagaagcctt tctggatgct cacttgaata
    60121 taaatgttga ccatgatttc cattttgtga agtataaaat gccagcattg gtttattcaa
    60181 tgatgatatc tccttgacaa cctcactagt agaattgtgt aggttaatat ccaaataaac
    60241 atccatttga gatttgagtt cttcaaattg atcgcttttc acttcaggat atagcttaac
    60301 atttttatat ttttttgcta gttcttgtaa cattggtccc ataactgtcc aagctgcgat
    60361 atggaatgtt accatagtaa aattcttaac aagataatct attttttgca attcttgaga
    60421 atttgtaaat gttaggcaat ggaaatcact accttcataa caacttagga atcttccatc
    60481 tcttctgtaa tctttaatcg cttgaaccat gactgaaact tcatcttttt tgaatactag
    60541 ttggccagta ttcccatgtt cagtcgtatc aaatgataga attggctttt ctaagatctt
    60601 catatcctct aaaatagtac ctaccacatg actgtagtta atgtccagat ataaatctac
    60661 acttctctcc agcttatcta atacaggagg aacaatttgt ggatgcaatc ttacattatc
    60721 atacacagct aattttatca gcttatcacc catattcgtc caagccgcga tatgaaatac
    60781 cacatcaggt agagctgtaa ctagctcttc tatcccttct aaatcttggg aattcgttaa
    60841 ggttaagcaa gaaaattcct tatctagagg cgatattagt tcaaattctc ccatatggtg
    60901 ttgtaaaatc tgactccact ccaaatcatg gaattcccac cataaatcac gataacgatt
    60961 ggctgtcaag gtggtccagg gttttctgta ggtcgtaaaa tgaatcacca ctggtttatc
    61021 attaaaagcc agatgttcct gccaattgtt atacaaagcc acaatatcat gccctacttg
    61081 taaattataa gctcgaccta gttctaacca atcatcttgc aagacttgat tgaaaatcgt
    61141 ttgatcacca ttaaaatgct cgaaacggcc ttcttcaact tccttcattg taacaatgct
    61201 ctgttcaatt agtcgttctt ttaatttctc ttgacgccat tttttattgt tgattaataa
    61261 aacacctgca ttaaatgtaa ttccatctgt atctttaact gctgcgagtg atttttcttc
    61321 taaacaaata ctaaataatt tctctaaaga agtatttaca atcaaatcac tgtctaaata
    61381 taaaaccgta tcttcttgga tataatctgc aataaaatat ctagcatagg taatgctact
    61441 aatgtggtct tgcttttccc aatcttgaaa cacagtttgt tcaggtagct tcacatcgat
    61501 aatctcacta cctaacatgc gagctatttt tcgtggcttt cgaaaccaat ctggcatgat
    61561 atcttgattt aaaatataaa tcttaacatc tcgattgtgg tatagaatag attttatggt
    61621 tgtttctaac tgcctggtgt aattacgatc accagctaat acaattgttt tgttcatttc
    61681 actcccttaa tcaattccca agtgataaat cgcatctacc aatagctttt tagtgaaata
    61741 accttctttt agcaaataac taaaggtttt tatccgattc gtcatttctt gatattcttg
    61801 tagattcatt ttatcaacta tctcatgaac ttcctctaga ctattcgcca taaaacctaa
    61861 gccctgatct actataaatt tagcagttga taagttgctc ggtacaatga ctgggatgcc
    61921 cgctgtcaga taggtactaa ccttatgaga tatatttaaa gtatagtatt gattgctttc
    61981 tccgtcattt tgatgggttc cccagacaag accaaagcca ccttttgata attctagcaa
    62041 cagttcctca tcttttttcc atccttcaat gctaagattt ctagcattgg aactagcttc
    62101 ccctttattt gaaaacaccc tcaaaggcgt atcttgaaac caattttgta agtctggaaa
    62161 acgctctaaa cttccagcaa aaaaaagttc ttttttaaaa gcaggggtgt ataaggataa
    62221 atcatgagga tgatcccaca tcccttgaac aagaatcttc ttagtcgtca atccttcttc
    62281 catcaggcgt gttttcatct gttcagatgg aacaatcaaa atatccgata gattatacat
    62341 atacagatag tctttcatga gatagtaatt actatcaaac atgaggggaa caacatcatg
    62401 gataaaacaa ataattttca cctgcatatc cttcagctta tcaaacaaga gacgatcaaa
    62461 ctcaaagcca ttccaagttg gagactgaaa gactaagata tcaccaatag agatactggc
    62521 cataatacca tccagacgct tattcatttc agaaggacta tctgaagcaa tgttgtaaaa
    62581 ataaatacca acctctctaa atcccagttg actagctatc ttttgaacag cattttgagc
    62641 taagataacc gtactatcac cagccatgcc gtataaattt gttaaatgta gtttcatatt
    62701 tcttatcttt ttaaaattca ctttaagaat agaaaactct ttttctttaa tctgattttt
    62761 agaa
//
LOCUS       DAVLTT010000007        50448 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLTT010000007 DAVLTT010000000
VERSION     DAVLTT010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50448
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.007"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(195..653)
                     /locus_tag="VYN15_000455"
     CDS             complement(195..653)
                     /locus_tag="VYN15_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV1451826.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(650..1090)
                     /locus_tag="VYN15_000456"
     CDS             complement(650..1090)
                     /locus_tag="VYN15_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1451827.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1446..3395
                     /gene="mutL"
                     /locus_tag="VYN15_000457"
     CDS             1446..3395
                     /gene="mutL"
                     /locus_tag="VYN15_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV1451828.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(3720..4187)
                     /locus_tag="VYN15_000458"
     CDS             complement(3720..4187)
                     /locus_tag="VYN15_000458"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV1451829.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(4188..5393)
                     /locus_tag="VYN15_000459"
     CDS             complement(4188..5393)
                     /locus_tag="VYN15_000459"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV1451830.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(5413..6048)
                     /gene="ribE"
                     /locus_tag="VYN15_000460"
     CDS             complement(5413..6048)
                     /gene="ribE"
                     /locus_tag="VYN15_000460"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV1451831.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(6033..7133)
                     /gene="ribD"
                     /locus_tag="VYN15_000461"
     CDS             complement(6033..7133)
                     /gene="ribD"
                     /locus_tag="VYN15_000461"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV1451832.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(7267..7381)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7538..8131
                     /gene="ruvA"
                     /locus_tag="VYN15_000462"
     CDS             7538..8131
                     /gene="ruvA"
                     /locus_tag="VYN15_000462"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV1451833.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            8141..8704
                     /locus_tag="VYN15_000463"
     CDS             8141..8704
                     /locus_tag="VYN15_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV1451834.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKLFATRANAQ
                     VFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            8701..9378
                     /locus_tag="VYN15_000464"
     CDS             8701..9378
                     /locus_tag="VYN15_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1451835.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIIMV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(9532..10563)
                     /locus_tag="VYN15_000465"
     CDS             complement(9532..10563)
                     /locus_tag="VYN15_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV1451836.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIIPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(10818..11501)
                     /locus_tag="VYN15_000466"
     CDS             complement(10818..11501)
                     /locus_tag="VYN15_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV1451837.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(11513..12457)
                     /locus_tag="VYN15_000467"
     CDS             complement(11513..12457)
                     /locus_tag="VYN15_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1451838.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            12589..15420
                     /gene="uvrA"
                     /locus_tag="VYN15_000468"
     CDS             12589..15420
                     /gene="uvrA"
                     /locus_tag="VYN15_000468"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV1451839.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            15413..16474
                     /locus_tag="VYN15_000469"
     CDS             15413..16474
                     /locus_tag="VYN15_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1451840.1"
                     /translation="MNKRVQAFLAKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            16606..17004
                     /gene="spx"
                     /locus_tag="VYN15_000470"
     CDS             16606..17004
                     /gene="spx"
                     /locus_tag="VYN15_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV1451841.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            17070..17639
                     /locus_tag="VYN15_000471"
     CDS             17070..17639
                     /locus_tag="VYN15_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1451842.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGTATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            17726..17992
                     /locus_tag="VYN15_000472"
     CDS             17726..17992
                     /locus_tag="VYN15_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV1451843.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            17996..18415
                     /gene="ruvX"
                     /locus_tag="VYN15_000473"
     CDS             17996..18415
                     /gene="ruvX"
                     /locus_tag="VYN15_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV1451844.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            18431..18736
                     /locus_tag="VYN15_000474"
     CDS             18431..18736
                     /locus_tag="VYN15_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV1451845.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            18995..20245
                     /locus_tag="VYN15_000475"
     CDS             18995..20245
                     /locus_tag="VYN15_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1451846.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLHPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTDFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            20242..20799
                     /locus_tag="VYN15_000476"
     CDS             20242..20799
                     /locus_tag="VYN15_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV1451847.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            20945..22477
                     /gene="cls"
                     /locus_tag="VYN15_000477"
     CDS             20945..22477
                     /gene="cls"
                     /locus_tag="VYN15_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV1451848.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            22555..22698
                     /locus_tag="VYN15_000478"
     CDS             22555..22698
                     /locus_tag="VYN15_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451849.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            22735..24273
                     /locus_tag="VYN15_000479"
     CDS             22735..24273
                     /locus_tag="VYN15_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1451850.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            24393..26600
                     /gene="nrdD"
                     /locus_tag="VYN15_000480"
     CDS             24393..26600
                     /gene="nrdD"
                     /locus_tag="VYN15_000480"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV1451851.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLVDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLSEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            26612..26752
                     /locus_tag="VYN15_000481"
     CDS             26612..26752
                     /locus_tag="VYN15_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451852.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKYSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            26796..27302
                     /locus_tag="VYN15_000482"
     CDS             26796..27302
                     /locus_tag="VYN15_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1451853.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            27295..27885
                     /gene="nrdG"
                     /locus_tag="VYN15_000483"
     CDS             27295..27885
                     /gene="nrdG"
                     /locus_tag="VYN15_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV1451854.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            27882..28499
                     /locus_tag="VYN15_000484"
     CDS             27882..28499
                     /locus_tag="VYN15_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV1451855.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTSAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTAGLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFRPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            28765..29073
                     /gene="rpsJ"
                     /locus_tag="VYN15_000485"
     CDS             28765..29073
                     /gene="rpsJ"
                     /locus_tag="VYN15_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV1451856.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            29290..29916
                     /gene="rplC"
                     /locus_tag="VYN15_000486"
     CDS             29290..29916
                     /gene="rplC"
                     /locus_tag="VYN15_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV1451857.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            29941..30564
                     /gene="rplD"
                     /locus_tag="VYN15_000487"
     CDS             29941..30564
                     /gene="rplD"
                     /locus_tag="VYN15_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV1451858.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            30564..30860
                     /locus_tag="VYN15_000488"
     CDS             30564..30860
                     /locus_tag="VYN15_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV1451859.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            30878..31711
                     /gene="rplB"
                     /locus_tag="VYN15_000489"
     CDS             30878..31711
                     /gene="rplB"
                     /locus_tag="VYN15_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV1451860.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            31815..32096
                     /gene="rpsS"
                     /locus_tag="VYN15_000490"
     CDS             31815..32096
                     /gene="rpsS"
                     /locus_tag="VYN15_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV1451861.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            32108..32452
                     /gene="rplV"
                     /locus_tag="VYN15_000491"
     CDS             32108..32452
                     /gene="rplV"
                     /locus_tag="VYN15_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV1451862.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            32465..33118
                     /gene="rpsC"
                     /locus_tag="VYN15_000492"
     CDS             32465..33118
                     /gene="rpsC"
                     /locus_tag="VYN15_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV1451863.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            33122..33535
                     /gene="rplP"
                     /locus_tag="VYN15_000493"
     CDS             33122..33535
                     /gene="rplP"
                     /locus_tag="VYN15_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV1451864.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            33545..33751
                     /locus_tag="VYN15_000494"
     CDS             33545..33751
                     /locus_tag="VYN15_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV1451865.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            33776..34036
                     /gene="rpsQ"
                     /locus_tag="VYN15_000495"
     CDS             33776..34036
                     /gene="rpsQ"
                     /locus_tag="VYN15_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV1451866.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            34062..34430
                     /gene="rplN"
                     /locus_tag="VYN15_000496"
     CDS             34062..34430
                     /gene="rplN"
                     /locus_tag="VYN15_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV1451867.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            34508..34813
                     /gene="rplX"
                     /locus_tag="VYN15_000497"
     CDS             34508..34813
                     /gene="rplX"
                     /locus_tag="VYN15_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV1451868.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            34837..35379
                     /gene="rplE"
                     /locus_tag="VYN15_000498"
     CDS             34837..35379
                     /gene="rplE"
                     /locus_tag="VYN15_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV1451869.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            35397..35666
                     /gene="rpsN"
                     /locus_tag="VYN15_000499"
     CDS             35397..35666
                     /gene="rpsN"
                     /locus_tag="VYN15_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV1451870.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            35951..36349
                     /gene="rpsH"
                     /locus_tag="VYN15_000500"
     CDS             35951..36349
                     /gene="rpsH"
                     /locus_tag="VYN15_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV1451871.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            36541..37077
                     /gene="rplF"
                     /locus_tag="VYN15_000501"
     CDS             36541..37077
                     /gene="rplF"
                     /locus_tag="VYN15_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV1451872.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            37161..37517
                     /gene="rplR"
                     /locus_tag="VYN15_000502"
     CDS             37161..37517
                     /gene="rplR"
                     /locus_tag="VYN15_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV1451873.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            37535..38029
                     /gene="rpsE"
                     /locus_tag="VYN15_000503"
     CDS             37535..38029
                     /gene="rpsE"
                     /locus_tag="VYN15_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV1451874.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            38001..38225
                     /gene="rpmD"
                     /locus_tag="VYN15_000504"
     CDS             38001..38225
                     /gene="rpmD"
                     /locus_tag="VYN15_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV1451875.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            38370..38810
                     /gene="rplO"
                     /locus_tag="VYN15_000505"
     CDS             38370..38810
                     /gene="rplO"
                     /locus_tag="VYN15_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV1451876.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            38823..40133
                     /gene="secY"
                     /locus_tag="VYN15_000506"
     CDS             38823..40133
                     /gene="secY"
                     /locus_tag="VYN15_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV1451877.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            40284..40922
                     /locus_tag="VYN15_000507"
     CDS             40284..40922
                     /locus_tag="VYN15_000507"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV1451878.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            41039..41257
                     /gene="infA"
                     /locus_tag="VYN15_000508"
     CDS             41039..41257
                     /gene="infA"
                     /locus_tag="VYN15_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV1451879.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            41282..41398
                     /gene="rpmJ"
                     /locus_tag="VYN15_000509"
     CDS             41282..41398
                     /gene="rpmJ"
                     /locus_tag="VYN15_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV1451880.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            41416..41781
                     /gene="rpsM"
                     /locus_tag="VYN15_000510"
     CDS             41416..41781
                     /gene="rpsM"
                     /locus_tag="VYN15_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV1451881.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            41799..42182
                     /gene="rpsK"
                     /locus_tag="VYN15_000511"
     CDS             41799..42182
                     /gene="rpsK"
                     /locus_tag="VYN15_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV1451882.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            42225..43160
                     /locus_tag="VYN15_000512"
     CDS             42225..43160
                     /locus_tag="VYN15_000512"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV1451883.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            43172..43558
                     /gene="rplQ"
                     /locus_tag="VYN15_000513"
     CDS             43172..43558
                     /gene="rplQ"
                     /locus_tag="VYN15_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV1451884.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            43823..44089
                     /locus_tag="VYN15_000514"
     CDS             43823..44089
                     /locus_tag="VYN15_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV1451885.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAIVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            44099..45436
                     /locus_tag="VYN15_000515"
     CDS             44099..45436
                     /locus_tag="VYN15_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV1451886.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMRVNGASSVDFISRGGQIPAPIHSFKN"
     gene            45680..46372
                     /locus_tag="VYN15_000516"
     CDS             45680..46372
                     /locus_tag="VYN15_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1451887.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(46475..48121)
                     /locus_tag="VYN15_000517"
                     /pseudo
     CDS             complement(46475..48121)
                     /locus_tag="VYN15_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(48111..49203)
                     /locus_tag="VYN15_000518"
                     /pseudo
     CDS             complement(48111..49203)
                     /locus_tag="VYN15_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(49216..50337)
                     /locus_tag="VYN15_000519"
                     /pseudo
     CDS             complement(49216..50337)
                     /locus_tag="VYN15_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
BASE COUNT        15185 a         9515 c        11048 g        14700 t
ORIGIN      
        1 aatctgaaat aactgttatg atatagcaga ttgaaactag aatagtacac ttttacttct
       61 aaaacattgt tagaaatcga tttgactgtc ctgattgatt tatcctgttc ttatttcatt
      121 tcactatagt aaggtgcagc aggataaagc aaaaccgaga agtttctttc tcggttttgc
      181 ttattatgag gttcctattt tctatgctcc aagagttgat tgatgtgatc tactttttta
      241 gcctctcttt tatagagaat agcccagatg atgagataga caatcgcaaa ctcgataatg
      301 agctggaggt agaaaatcca gtggaagggg aaccaaccag caagagttgc tagtgggaca
      361 aagccagcca gcataaggaa gaaatgagtc agagtggcac gaagcatgct ccagtcacgg
      421 ctgaataagc ggttgccaaa gttgaagagc ataccgatgg ctgcccagat aagtgtgcag
      481 tagagcaaga ccagggcacc gtgaacctga tgctgatcca tcacttggcc gatgagagag
      541 tagggattta gtggtgcgta ggtatttggt gcataaatga gtgaaaagag gatggagagg
      601 atgaggccga taagaacacc ggcagctgca tcgtgaaata cttgtttttt catagttcta
      661 atttctcctt gatggttttt agataacggc gtgaagagta ggtgaagctt tcgtttttca
      721 agaaaatttc taccagaccg tttggcgtga gcttgaggtg agagatggaa tcgatattga
      781 tgatttctga ttgggaaatt tggataaaat tggttggcaa gagtttaaga acctgataga
      841 gtcgcaaatc aatgctgtag gtctgactcg cggtttctgc tagaaccttc cgattctcga
      901 tatagaagcg ctgaatcttg ccaatctcaa ctagatagac ctgatcatcg atttttcctt
      961 tgattttttc tctttggtcc agattttctg cgaactcgat gactttctgg actttttcgg
     1021 tttcttgagg tgcttggaca atcagctttt cctcctcgta agtctcacta atctgtagtt
     1081 ctactttcat aaatttctct ccttgttttt catacaaaat taatctcact tcttgtacac
     1141 ctttattaat actcttcaaa aatctcttca aaccacgtca gcgtcgtctt gccgtaggat
     1201 agttgttgac tttgtcagtt ttatctacaa cctcaaaaca gtgttttgag ctgtctgcgt
     1261 ctagctttct agtttgctct ttgattttta ttgagtatac cactatttta ctccctctgg
     1321 caagggactt tgtctatgtg gagggattgg gctcctatgt ggtggagttt ttctgttctt
     1381 tctgaaatat ggtataatag cactaattaa tttctaggaa aatagataca gaaaggggct
     1441 gaaagatgtc tcatattatt gaattgccag agatgctggc aaaccaaatc gcagctgggg
     1501 aggtcattga acgtcctgcc agtgtggtta aagagttggt agaaaatgcc attgacgcgg
     1561 gctctagtca gattatcatt gagattgagg aagctggtct caagaaggtt caaatcacgg
     1621 ataacggtca tggaattgcc cacgatgagg tggagttggc cctgcgtcgc catgcgacca
     1681 gtaagataaa aaatcaagca gatctctttc ggattcggac gcttggtttt cgtggtgaag
     1741 ccttgccttc tattgcgtct gttagtgtct tgactctgtt aacggcggtg gatggtgcta
     1801 gtcatggaac caagttagtc gcgcgtgggg gtgaagttga ggaagtcatc ccagcgacta
     1861 gtcctgtggg aaccaaggtt tgtgtggagg atctcttttt caacacgcct gcccgtctca
     1921 agtatatgaa gagccagcaa gcggagttgt ctcatatcat tgatattgtc aaccgtctgg
     1981 gcttggccca tcctgagatt tcttttagct tgattagtga tggcaaggaa atgacgcgga
     2041 cagcagggac tggtcaattg cgccaagcaa tcgcagggat ttacggtttg gtcagtgcca
     2101 agaagatgat tgaaattgag aactctgacc tagatttcga aatttcaggt tttgtgtctt
     2161 tacctgagtt gactcgggct aaccgcaatt atatcagcct cttcatcaat ggccgttata
     2221 tcaagaactt cctgctcaat cgtgctattt tggatggttt cggaagcaag cttatggttg
     2281 gacgttttcc actggctgtc attcacatcc atatcgaccc ttatctagcg gatgtcaatg
     2341 tgcatccaac taagcaagag gtgcggattt ccaaggaaaa agaactgatg accctggttt
     2401 cagaagctat tgcaaatagt ctcaaggaac aaaccttgat tccagatgcc ttggaaaatc
     2461 ttgccaaatc gaccgtgcgc aatcgtgaga aggtggagca aactattctc ccactcaaag
     2521 aaaatacgct ctactatgag aaaactgagc cgtcaagacc tagtcaaact gaagtagctg
     2581 attatcaggt agaattgact gatgaagggc aggatttgac cctgtttgcc aaggaaacct
     2641 tggaccgatt gaccaagcca gcaaaactgc attttgcaga gagaaagcct gctaactacg
     2701 accagctaga ccatccagag ttagatcttg ctagcatcga taaggcttat gacaaactgg
     2761 agcgagaaga agcatccagc ttcccagagt tggagttttt cggacaaatg cacgggactt
     2821 atctctttgc ccaagggcga gatggacttt acatcataga tcagcacgct gctcaggaac
     2881 gggtcaagta cgaggagtac cgtgaaagca ttggcaatgt tgaccagagt cagcagcaac
     2941 tcctagtgcc ctatatcttt gaatttcctg cggatgatgc cctgcgtctc aaggaaagaa
     3001 tgcctctctt agaggaagtg ggcgtctttc tagcagagta cggagaaaat caatttattc
     3061 tacgtgaaca tcctatttgg atggcagaag aagagattga atcaggcatc tatgagatgt
     3121 gcgacatgct ccttttgacc aaggaagttt ctatcaagaa ataccgagca gagctggcta
     3181 tcatgatgtc ttgcaagcga tctatcaagg ccaatcatcg tattgatgat cattcagcta
     3241 gacaactcct ctatcagctt tctcaatgtg acaatcccta taactgtcct cacggacgtc
     3301 ctgttttggt gcattttacc aagtcggata tggaaaagat gttccgacgt attcaggaaa
     3361 atcacaccag tctccgtgag ttggggaaat attaaaagta taaaaaagtc tgggaaaaat
     3421 tttcaaaatc agaaaaacgc ataaaatcag gtgttcaaaa accttgattt tatgcgtttt
     3481 atcatggaaa tagttacttc atgttttcct aattcttttc gaaactcttt ttaaaccacg
     3541 tcagttttat cagtaatctc aaaacagtgt tttgagctaa ttttgccagt tttgtctgta
     3601 acatcgaagt tgtgttttac cactctgcga ctggtttcct agtttgctct atgattttca
     3661 cagagtatta aaatgcgatt ttgccaagtt tctttattcg tctaaaagta gagtctgttc
     3721 tatgcgtcta atgtacgaat taggttgacc atttcaatag ctccttgtgc acactcagaa
     3781 cccttatttc ctgctttggt accagctcgt tctatggctt gttcaattgt atctgtcgtt
     3841 agcacaccaa acataacagg aatttcgcta tttaaactga tttgggcgat tcccttagat
     3901 acctcgctac atacataatc ataatgactt gtattccctc taatgacagc tcccaagcag
     3961 ataattgcat catatttttt actttttgcc atttttgatg caatcagtgg tatttcaaaa
     4021 gctcctggaa cccaggctac ctctatatct ttctcgttta cattctctct tttgagatta
     4081 tctagtgctc cagataataa ttttgaagtt ataaattcat taaatctcgc tacaacaata
     4141 cctattttaa tattgtttgc tactaaatta ccttcataag tgttcattta tttttcctcc
     4201 atatttaaaa tgtgacccat tcgatttttc tttgtttcta aataaaaact atcgtaagga
     4261 ttggcttcta tttcgattga tattctactg gaaatggtaa ttccatattt ttctaactgt
     4321 tcaaccttgt caggattatt tgtcagtaaa tgaagtgact gaagtcccag atctttaagc
     4381 atttgtgctc caatatgata ttctcttaaa tcaccttcaa agcctaatgc aagattggca
     4441 tcaagcgtat ccatgccttg atcttgtaaa tgataggctt ttaatttatt gataagtcca
     4501 attcctcgtc cctcctgtcg caagtaaagt aagacacccg aaccattctc aacaatcatt
     4561 ttcatagctt tatcgaattg ctgtccacaa tcgcaacgta aagagcctaa aacatctcct
     4621 gttaaacatt cggagtggac ccgacataat acattggctt catcctctat gtttcccata
     4681 ataagagcaa gatgatgttc cccatttagt ttatctatat agctaattgc tttgaaatta
     4741 ccgtatctag taggcatatt gacagttgaa actcgttcta ccagctgatc atatactttt
     4801 ctatattctt gtaattcttt gatggtaatt agtggaatgt tgtgtttctt cgaaaactga
     4861 attaaatcat ctgttctcat cattttgcca tcatgattca ttatttcaca acataggcca
     4921 cactctttta gtccagctaa ttttaataaa tcaacagttg cttctgtgtg tccatttctt
     4981 tctagaacac cacctttttt tgcaattaaa ggaaacatgt gtcctggcct gcgaaaatca
     5041 gagggtgtta tatcttcagc tacacacata cgtgcggtca gtcctctttc ctcggcagaa
     5101 atacctgtgg tcgtttcttt ataatcaatt gaaactgtaa aagcagtctt atgattatct
     5161 gtattgtttt caaccatagg tgaaagcatt aattgattag ctaaactttc gctcataggc
     5221 atacaaatta atcctttggc ataagtagcc ataaaattaa cattttctgt tgtagctgct
     5281 tgtgcagaac aaattaagtc tccttcattt tctctatcct tgtcgtctat aacaagaaca
     5341 agtcgtccct tctgcaatgc ttctaatgct tcttgtattt ttcgatattc cattgactga
     5401 ttatcctttc tgctaaaatc cattttgata taatagttcc ttagatattt ctgattttgg
     5461 agagttatcc atcagttttt gcacatattt acctaagata tcattttcaa gatttactgt
     5521 actcccgact tgtttactct taagaatggt ttgttccaag gtatgaggga taacagatac
     5581 tgaaaagttt actttggaga ctttagcgac agtcagacta atgccgtcaa ttgtaataga
     5641 tcctttttca actattaaat ctaaaatttc tttttgtgtg ttgatttgat accatacagc
     5701 attatcatct ttttttattg acgagatttt tcctgtacca tcaatgtgtc ctgtaacgac
     5761 gtgaccccca agtcgaccgt tgacagataa ggctctttct agattcacct cacttccatg
     5821 ttttaataga gtaagagctg ttcgactcca tgtttcattc attacatcaa ctgtaaagga
     5881 ttgatggttg aaatgagtaa ctgtaagaca gataccattt actgctatac tatcgcctaa
     5941 atggatatcc gttaatattt ttgaggcttt aattgatagt ttacaattac gagagtcttt
     6001 ctgtattctt tcaacttttc cgatttcttc aattattcct gtgaacatgg ataaatcact
     6061 tcactttcta tgagatagtc atttcctatt tgagaaaaag cataaggttt caatctaata
     6121 gcgtcatttg gcaaagaaat gccttcacct ccgacaggaa acttggcact gcctccaaaa
     6181 atttttggtg caatatatat tttcagctca tcaacaattt gttgttccaa agcactccaa
     6241 ttcattagac tgcccccttc tagaactagg ctatcaatct gcatgtttcc tagatgttgc
     6301 attaaactcg ataagtctat atgattgcct tttttcttta tggaaagtat ttcacagcca
     6361 tgattttgat atagcttcat tttatttttg tcttcagagg aagtggcaat gtaagtttta
     6421 atatcatttg ctgtttttac gattttagag gtaagaggag ttcgtaaatg tgtatcgcat
     6481 atgatacgga taggattttt cccttcctcc aatctacatg tcagcaaagg atcgtcttga
     6541 ataacagtat tgactcccac cataattgca ctaacatggt gtcgtaactg atgcacatgc
     6601 tttcttgctt cttcttcagt aatccatttg gattgatttg ttttagtggc tatttttcca
     6661 tccattgaca ttgcatattt cataaaaaca tagggtacat gctgggtaat atactttcta
     6721 aaacttttta ttaagttaag acactcattt tctaaaattc caacagtaac ttgaagatta
     6781 ttttcctcaa gtatctttac tccttttcca gatacaatag gattacagtc taggcttcca
     6841 atgactactc ttgtaatacc actatcgatt atagcatcta tacagggagg tgttttcccg
     6901 aagtgacaac agggttcaag tgttacataa agcgtcgctc cgacagggga ttctctacag
     6961 tttttaagag catttctctc agcatgtggg ccaccaaaaa actcatgata accttgtccg
     7021 atgatgtgat tatcttttac aataactgcg ccgaccatag gattgggatt gacgtaacca
     7081 gccccttttt gtgccagttt tattgctaat ttcatatatt ttgaatcgct catctcacta
     7141 cctccaaaaa aatatgcctt gaatagggga ctactcaagg catacaaaag aaaacttatg
     7201 cgattaacaa aaatgctctg aaatgacaag taatcatttc agagcacgca aaaagcacaa
     7261 atatactttt atcttctttc atccagacta tactgtcggc tttggaattt caccaaatca
     7321 tgcctttcgg ctcgtgggct ataccaccgg tagggaattt caccctgccc tgaagatagt
     7381 tattcaatta cagatgatta tagtacttaa ttttgaatat gtcaacagat aaataccgat
     7441 tgtttttgat atactgtatt tgtgataatc gattctcgct cctcggataa agaaaatatg
     7501 atatactaga taaacgaaat aagagagaag gaatactatg tacgcatatt taaaaggaat
     7561 cattaccaaa attactgcca aatacattgt tcttgaaacc aatggtattg gttatatcct
     7621 gcatgtggcc aatccttatg cctattcagg tcaggttaat caggaggctc agatttatgt
     7681 gcatcaggtt gtgcgtgagg acgcccattt gctttatgga tttcgctcag aggatgagaa
     7741 aaagctcttt cttagtctga tttcggtctc tgggattggt cctgtatcag ctcttgctat
     7801 tatcgctgct gatgacaatg ctggcttggt tcaagccatt gaaaccaaga acatcaccta
     7861 cttgaccaag ttccctaaaa ttggcaagaa aacagcccag cagatggtgc tggacttgga
     7921 aggcaaggta gtagttgcag gagatggcct tcctgccaag gtcgcagtgc aagcaagtgc
     7981 tgaaaaccaa gaattggaag aagctatgga agccatgttg gctctgggct acaaggcaac
     8041 agagctcaag aaaatcaaga aattctttga aggaacgaca gatacagctg agaactatat
     8101 caagtcggcc cttaaaatgt tggtcaaata ggagcagaga atgacaaaac gttgttcgtg
     8161 ggtcaagatg accaacccac tctacatcgc ctatcatgat gaggagtggg gccagcccct
     8221 ccatgatgac caagcgttgt ttgagttgtt gtgtatggaa acctatcagg caggcctgtc
     8281 ttgggaaacg gtactcaaca aacgccaagc tttccgagaa gcctttcata gctatcaaat
     8341 tcactcagtc gcagagatga ctgacactga attggaagcc atgctggaga atccagctat
     8401 cattcgaaat agagccaagc tttttgctac acgcgctaac gcccaagtct ttctacagtt
     8461 acaggcagag tacggctctt ttgatgccta tctttggtct tttgttgagg ggaaaactgt
     8521 cgttaacgat gttcctgatt atcgccaagc gccagctaaa acacccttat ctgagaaatt
     8581 agccaaagat ctcaaaaaac gaggcttcaa gttcacaggc ccagtcgccg tattgtcttt
     8641 tctacaggct gcagggctag ttgatgacca cgagaatgat tgtgagtgga aaggtcttaa
     8701 atgatgtcta acaaaaataa gggaattctg atttttgcga ttctctatac agtcctcttt
     8761 gtgtttgatg gcgttaaatt gctggcttct ttaatgccat ctgtcattgc aaattatctt
     8821 gtttatgtag ttttagcttt atatggctcc ttcttgttca aggatagatt gatccaacaa
     8881 tggaaggaga ttagaaagac taaaagaaaa ttcttctttg gcgtcttaac aggatggctc
     8941 tttctcattc tgatgactgt tgtctttgaa tttgtatcag agatgttgaa gcagtttgtg
     9001 agactagatg gacaaggtct aaatcagtct aatattcaaa gtacctttca agaacaacca
     9061 ctactgatag ctgtttttgc ttgtgtcatt ggacctctgg tagaagaatt atttttccgt
     9121 caggtcttat tgcattactt gcaggaacgg ttgccaggtt tactaagcat tattatggta
     9181 ggacttgttt ttgctctgac tcatatgcac agtttggccc tatcagagtg gattggtgca
     9241 gttggttact taggtggagg ccttgccttt tctattattt atgtgaaaga aaaagagaat
     9301 atctactatc ccctacttgt tcacatgtta agcaacagcc tctccttaat cattttagct
     9361 atcagtatag taaaatgaaa taagaacagg acaaatcaat caggacagtc aaatcgattt
     9421 ctaacaatgt tttagaagta gatgtgtact attctagttt caatttgctg taatatgtga
     9481 tgaaaatgcc agtaatgata ccgagaaaaa gctgagaaac ttttcccagc tttatttgtt
     9541 atagtcaaag cgaatgactt gttcctgtgc atctacatga gcatggaccc caaagggtat
     9601 aattgctctt ggagttgcgt ggccgacatt cagattatag acaatcggga tattgctgtc
     9661 aatgatatcc aatagtgcct ctttatagtc gtcatggaaa gtttcatcca taggttttcc
     9721 gaccaagagt ccattgatga ccgcgaatat gccagtgtcc tttaaagtta gcaacatctt
     9781 tttgaagtct tctggcttag gcttttcttc gcttgtttcg agcaagagga ttttcccttc
     9841 ccagtctgac aagtcaggga aaagtttgta tttttggcag agctccgtgc tatctgcgta
     9901 tcgagagttg tcaaagatat cgtagaggga ttcgaggcaa ccaccgagga ttttcccctc
     9961 gaattgggcc cttccttgca acaagtcaaa acctgtattt gtatgactga cacgaggtgt
    10021 tcccagggcc gtgggactaa aatcagttcg ttcctcatac caaacgtcac tagggcggat
    10081 ttctgaaatt cttcccgtct caatcaattc tttaaagtag tgaaggctat aggctagcat
    10141 ttctttgtct aattcacaaa tgtctgctaa aaaggattga ccataaaaag tcttgattcc
    10201 taatttatgc aacatgaggt ggttcatggt tgtatccgag aagccaagaa aaattttttg
    10261 cttgataacc ttttggagtt ggtcattttc aaaaagataa ggtagcaagc gataggtatc
    10321 gtctccaccg atggcacata ggatcatgtc gatgctatca tcagaaaagg catgaatcaa
    10381 atcctctgca cgagcttcag gatggtcctt gataaagtct aatcctttta acgaatgggg
    10441 caaaaagatg ggattgagtc ccagatcctt gagacgttgg atacccaagt ccacttcgtg
    10501 tttgacaaaa tcctctccga taatgccact agataaacta acaataccaa tagtagaaac
    10561 catatctcat cctcctagaa atagattgag cctattttat cacaaaatat aagagaaagc
    10621 tatgtgggat ttcagaagaa tacttttaat actcttcgaa aatctcttca aaccacgtca
    10681 gttttatctg caacctcaaa gctgtgcttt gagcaacctg cagctagctt cctagtttgc
    10741 tctttgattt tcattgaata taactcaaaa aagtaagtga aaaagcaacc gcacctgcag
    10801 ttgcttttat cgttttctta ttcttgatag cgtgttggtc ctgcacttgc actacggata
    10861 ttcaagcgtt tcttgagata gaagcgaagg gctaggaggg ctgctccaat aatagctagt
    10921 ggcaatggat ccagtactgg gttaaggcta gctggtagga agcttgttgc aaagaagaca
    10981 agcaaccaaa ggaacataga agctaggata actagtacag atttccagaa aggtggacgt
    11041 tgactgcgat ccatatctgg tccatagtat tggtaaacaa agtagtacat caagtagaag
    11101 gcaaatccac caaccagtcc aactaataga agagtaatca atccatagcc gaaagcttgg
    11161 tctgccgcaa agaaggttgt gagggcgctg acaagggcaa agaggctagt gatgaaaaga
    11221 gctgagtcca taatcatcag ttttgggtca tcattttctt ttggatgctc tttttcgtac
    11281 tgctctttga cagtgaagct atgagcccaa tgagttggtg cgccgtatag ggaacgggca
    11341 gttgtacctt tagattgctc ctcaaggatt tggggaatga cttcctcaaa aatagtctgg
    11401 atttcagcgt ctgttttccc atctttgatg aattgttggg tagcaatgtg gacaaactct
    11461 tggtttttct tagttaattt ttgtagatca atttgagaca taggaactcc tcttagaacc
    11521 attttttatg gatgagatag agagtgagcg agacactcat agcaaaggcg ataaagacga
    11581 ttaaccagaa ggcatttggc tctccgttta gggggatttc attatcctta aagttcatcc
    11641 cgtaggcaga aaagaccatg gttgggatgg acatgacgat ggtcacaagg gccaaggttt
    11701 tcatgatgtt gttctggttg ttagaaatga tagaggcaaa ggtctctgtc atagaatgca
    11761 agacgtttcc ataaatatct gccatctcga tggcctgttg ggtttcaatc agggtgtctt
    11821 caagcaggtc ttcgtcctca aggtatttct tgatattgct ggttgaactg gtcaatttct
    11881 taatcacgcg ctcatttgtt ttgagggagg ccttgaaata gacgatagtt ttttccaatt
    11941 ccatgagctc aatcaattct tcattacgag ttgattgatg cagttgactt tcgatttgtt
    12001 cactcttgcg gtcgattgaa cgaagggctg ttaggtaaag ctctgcattg cgataaagaa
    12061 tttgaaagat aaaacgtgaa cgcatgaagg tatagaaatt acgcaatcga cggttgataa
    12121 agacatcaag gacaggtagt ggttccaaac acgtagtgat aatggtttcc tcagtgatga
    12181 taataccaag cgggatggtt acgtagtagg tgcggttatt tctttcctcc gtgaccggca
    12241 cgtctacgat aatcagggta tactcgtctt caatggtaat acgagacatt tcttccgcat
    12301 cgagcggtgc tcgaaggtcg gcaatatcaa tatcgaaggt gttggcgatt tcgagtgatt
    12361 cattttgagt cggattgacg agattgatcc aagtacccgg ttcaagcgta tcgatctctt
    12421 taaattcagt tgttgtagag agaaaaactt gtttcatatc ccttatcctt tctcattttt
    12481 cagatttttt cacactgtac tattatacta caaaatcggc cttttgggta atagaatctc
    12541 actttttttg gtataatggt aagcaataat ggactagaaa gaacaaagat gcaagataaa
    12601 attgtcattc atggggcgcg tgcccataat ttaaaaaata ttgatgtgga gattccgcga
    12661 gacaagttgg ttgtcgtgac tggcttgtca ggttcaggga agtccagtct ggcttttgat
    12721 accctctatg cggagggaca acgtcgctat gtagagagtt tgtccgccta cgctcgtcag
    12781 ttcttgggaa atatggaaaa accagatgta gatgccattg atggtctcag cccagctatt
    12841 tccatcgacc agaaaacgac tagtaaaaat cctcgctcga cggtgggaac gacgactgaa
    12901 atcaatgact atctgcgtct cctctacgca cgtgtgggga cgccttactg tatcaacgga
    12961 catggagcta tcaatgcttc ttctgtggag caaatcgttg ataaggtttt ggagttacct
    13021 gaacgccagc gcttgcagat cttggctcct gtcatccgca agaaaaaagg ccaacataag
    13081 agtgttatcg agaaggttca gaaagacggg tatgttcgtg ttcgtgtgga tggggaagtc
    13141 tatgatgtga ccgaagtgcc agagttgtct aagagcaagc aacacaatat cgatgtcgtg
    13201 gttgaccgta ttgttatcaa ggagggcatt cgtagccgtc tctttgattc cattgaagct
    13261 gcccttcgta tcgcagaagg ttatgtgatt atcgacacca tggacgactc tgagttgttg
    13321 ttctctgagc attatgcctg tccagtttgt ggatttactg tcccagagtt agaacctcgt
    13381 ctcttctctt tcaatgctcc ctttggctct tgtagtgagt gtgacggctt ggggattaag
    13441 ctggaggtgg atactgattt ggtagtgcca gatgccagca aaaccttaca tgagggagcg
    13501 ctggcacctt ggaatcctat ctcatccaac tactatccaa acatgttaga gcaggccatg
    13561 aaagtctttg gagtggctat ggataagcct tttgaggacc tgtcagaaga agataagaac
    13621 ttgattctct acggctcaga tggtaaggaa ttccatttcc attatgaaaa tgaatttggt
    13681 ggtgtgcgcg atatcgacat tccgtttgag ggagttatca ataatatcaa acgtcgttac
    13741 catgaaacca atagcgatta cactcgcact cagatgcgtc tctacatgaa tgagctgacc
    13801 tgcggaacct gtcaaggcta tcgtctcaat gaccaggcct tgtctgtccg tgtgggcggc
    13861 cagcaagggc cacatattgg agaaatctca gacctgtcta tcgctgacca cttggacttg
    13921 gtgagccagt taactttgtc tgaaaatgaa gccatcattg ctcgtcccat tctcaaggaa
    13981 atcaaggatc gtttgacctt ccttaataat gtgggtctta actatctaac cctgtcacgt
    14041 tcagcaggaa ccctttcagg tggggaaagt cagcgcattc gtttggcaac ccagattggt
    14101 tccaacctat caggtgtcct ctatatccta gacgagccgt caatcggtct tcaccagagg
    14161 gacaatgacc gcctgattgc cagtctgaaa aagatgcgtg acttgggcaa tactcttatc
    14221 gtggtggaac acgacgaaga taccatgcgt gaagctgatt atctgattga cgttggtcct
    14281 ggtgccggtg tttttggtgg tgagattgtt gcagcaggta cacctaagca agtggctcgc
    14341 aacagcaagt ctatcacagg tcagtacttg tcaggcaaac gtgtcatccc agtaccagaa
    14401 gagcgccgtg tcggaaatgg tcgttttatt gaagtgatag gagcgcgtga gaacaacttg
    14461 caaaatgtca cggctcgctt tccactagga aaatttatcg cagtgacagg tgtgtcgggt
    14521 tcagggaaat cgactctaat caacagcatt ctcaaaaaag ccattgccca gaagctcaac
    14581 cgtaattcag acaaacctgg taagtttaag actattacag ggattgagca tgtcgaccgt
    14641 ttgattgata ttgaccagag ccctatcgga cggacgccga ggtctaaccc agctacctat
    14701 acaggagttt ttgacgatat acgtgacctt tttgctcaga caaatgaagc caagattcga
    14761 ggctacaaga aggggcgctt cagtttcaac gtcaagggag gtcgctgtga agcttgctca
    14821 ggtgacggga ttatcaagat tgagatgcac ttcttgccag atgtttatgt ggcttgtgaa
    14881 gtttgccacg gaacccgcta taacagtgaa accctagaag ttcactacaa ggaaaagaat
    14941 atttcgcagg tcttggatat gacggtcaac gatgcggtag aatttttcca acacattccg
    15001 aaaattcaac gcaaactcca gaccatcaag gatgtagggc taggctatgt gaccttggga
    15061 cagccagcta ccaccctttc tgggggagaa gcccaacgta tgaagttagc tagcgaactc
    15121 cacaaacgct cgacaggaaa atctttctac attctggatg agccgacgac agggcttcat
    15181 acagaggaca ttgctcgcct gctcaaggtt ttagctcgct ttgtagacga tggcaataca
    15241 gtcctcgtca tcgagcacaa tctggatgtt atcaagacgg cagaccatat cattgacttg
    15301 ggacctgagg gcggtgtcgg tggtggaacc atcatcgtaa caggaactcc agaagaagta
    15361 gctgccaacg aagccagcta tacaggacac tatttgaaag gaaagttaca tcatgaataa
    15421 acgcgtacaa gcatttctag ctaaaatgca agaaaaagaa ctagatggtg tcatcatcaa
    15481 caatcttaaa aacgtctatt atttgactgg tttttggggc tcaaacggaa cagtctttat
    15541 cagccgtgac cgtcaggtct tagtgacaga ctctcgctat atcatcgcag ctaagcaaga
    15601 aaccagtggt tttgagattg tggctgatcg tgatgaattg gctgtcattg caggaattgt
    15661 taaggacatg ggcttgactc gtatcggttt tgaagatgag atttcagtgt cttattacca
    15721 ccgtatgcag gcagcttttg caggtttgga cttgcttcca caaactcagt ttgtggaagg
    15781 tcttcgtatg attaaggatg aggcagagat tgcagcgatt cgcaaggctt gttctatctc
    15841 agaccaagct ttccgcgatg cgcttgactt tatcaaacca ggaaaaactg aaattgagat
    15901 tgccaacttc cttgatttcc gcatgcgtga gttgggagca tctggcttat cttttgatac
    15961 gatcctagct agcggtatca attcttctaa accccatgcc catccaatgc acaaaccagt
    16021 ggagttggga gaagccatta ccatggactt cggctgtctc tatgaccact atgtcagtga
    16081 tatgacccgg actatctatc tagggcatgt tagcgatgag caggcagaga tttacaatac
    16141 ggttctaaaa gctaaccaag ccttgattga ccaagctaag gcaggcttag gtttccgtga
    16201 ctttgacaaa atccctcgtg atattatcat tgaggcaggt tatggcgact actttactca
    16261 cggcattggc cacggtattg gtctggatat ccatgaggaa ccctacttta gccagacttc
    16321 tacagaaact attaagacag gtatggcctt gaccgatgaa ccaggtatct atatcgaagg
    16381 caaatatggc gttcgtatcg aggatgatat cctgattaca gagacaggtt gtgaattatt
    16441 gaccctagct ccaaaagagt tgatagtcat ttagttgttt gtcaagaaaa aagtacgaaa
    16501 atgacgaaaa aagtcaaaaa aaattaaaaa taggtcgcaa gtcggatgtt ttttatggta
    16561 taatagacta aactgatagt aacatgtagc gaaaggggta ggtacatgat taaaatttat
    16621 acagtctcaa gttgtactag ctgtaaaaaa gcaaaaacct ggctcaatgc ccaccagtta
    16681 agttataaag aacaaaacct tggtaaagaa ggaattacga gagaagaatt actggatatt
    16741 ctaaccaaaa cagataacgg aatagccagc atcgtttcgt ctaaaaatcg ctatgccaaa
    16801 gcccttggag tggatattga agatttgagt gtcaatgaag ttctcaatct gattatggaa
    16861 acaccgagaa ttttaaagag cccaatcctt gtagatgaaa aacgcctgca agttggctac
    16921 aaggaagacg atattcgtgc cttcctacca cgctctgtcc gtaatgtaga aaatgcagaa
    16981 gcacgtttac gtgcagctct ataaacatca aggctgggag cacttcccag tcttattcta
    17041 ttttaatttc aaaaagaaag aagagagaaa tgaaaaaaat agttcttgtt agtctagctt
    17101 tcctttttgt cctggttggt tgcggacaga aaaaagaaac tggaacagct acaaaaacag
    17161 aaaaggatac gcttcagtcg gcattgccag ttattgaaaa tgccgagaag aatacagttg
    17221 taaccaagac tttggtcttg cccaagtcag atgatggtag ccagcagaca caaacaatta
    17281 cttacaaaga caagactttt ttgagtctaa ctatccaaca aaaacgtcca gtctctgatg
    17341 agttgaagac ttatattgac caacatggag tggaggaaac tcaaaaagct cttcttgaag
    17401 cggaggagaa ggataagtct atcattgaag ctcgtaaatt ggcaggtttc aaacttgaaa
    17461 caaaactatt gagcgcaacg gaacttcaaa caacgactag ttttgatttt caagttctgg
    17521 atgtcaagaa ggcttcccag ttggaacatc tgaagaatat tggtttggaa aatcttttga
    17581 aaaatgaacc aagcaaatat atttcagata gattggcaaa tggcgcgaca gaacaataga
    17641 aaatccaaat aaatagactg cctgaattgt agaaggtaag gaattatgct ataatggtac
    17701 tattctaagg aaagagggtg ttagaatggg atttactgaa gaaacagtac gttttaaatt
    17761 ggacgattcc aataaaaaag aaattagcga aactttgaca gatgtttatg cttcgttgaa
    17821 cgataagggt tacaacccaa ttaaccaaat cgtaggttac gtattgagtg gagaccctgc
    17881 ctacgttcct cgttataata atgcacgaaa tcaaatccgt aagtatgagc gtgatgaaat
    17941 cgttgaggaa ttggttcgct actacctcaa aggacaagga gtcgatctat aacctatgag
    18001 aattatggga ttggacgtcg gttcaaaaac ggtaggggtg gcgattagcg atccgcttgg
    18061 ttttacagct caagggcttg aaatcatcca gataaatgaa gaacaaggcc aatttggttt
    18121 tgaccgcgtt aaggaattgg ttgatactta caaggtggaa cgatttgtag tgggcttgcc
    18181 taaaaacatg aacaatacaa gtggaccgcg cgtagaagct agtcaagcct acggagcaaa
    18241 gctagaagag ttttttggtt taccagtaga ctatcaggat gaacgcttga caacagtggc
    18301 tgctgagcgc atgttgattg aacaagcaga tatcagtcgc aataagcgca agaaagtcat
    18361 tgataagtta gcagctcagc tgattttaca aaattattta gatagaaaat tttaatataa
    18421 aggagaggct atgtcacacg atcataacca cgaccacgaa gaacgtgaac taatcacact
    18481 agtagatgag caaggaaatg aaaccttgtt tgaaatcctt ttgacaattg atggaaaaga
    18541 agaatttggt aaaaactatg ttcttctagt accagttaac gcagaagaag acgaagacgg
    18601 acaagttgaa atccaagctt actcattcat tgaaaatgaa gatggaacag aaggcgaatt
    18661 gcaaccaatc ccagaagact cagaagacga atggaacatg attgaagaag tcttcaacag
    18721 ctttatggag gagtgataca gtctgggaga ctgtatcagc ccaactccca gaaatgggga
    18781 agagttggaa cgtccagtga acatttttac cccaactctt agaaattgag aagagttgga
    18841 acatctagtg gatgttttta gcccatattc acattcatag tggctagtta ttagctaacc
    18901 aggtaagagg tcgggacgaa aatcctggcc ttgtttttat tagtaaccat actttaatgc
    18961 gataattgat tggacttttg tcaaggagat gtgtatgttt gaagtagaag aatggcttca
    19021 tagtcggatt ggtttgaatt ttcgatcagg tttgggccga atacagcaag cggtggattt
    19081 gttaggaaat cctgagcagt cttaccctat tatccacgta acagggacta atgggaaagg
    19141 atctaccatt gcttttatga gggaattatt tatggggcat ggcaaaaaag ttgcgacctt
    19201 tacctcccct catatcgtct ctatcaatga ccgaatctgc attaatgggc aacctatagc
    19261 agacgcagac tttatccgtt tggctgatca ggtcaaggag atggagaaaa cgcttctgca
    19321 aactcctgac cagttgtcct tttttgaatt gctgaccttg gttgcttttc tttattttag
    19381 ggagcaagag gtggatttgg ttttattaga agtgggaatt ggtggcttac ttgacacgac
    19441 caatgtggta actggagagc ttgctgtcat cacctccatt gggcttgacc atcaagaaac
    19501 cttgggtgat agtctagaag caattgcaga gcagaaagct ggtattttca aggctggtaa
    19561 gaaggcagtg attgcgaaat tgcatccaga agctaggctt gtctgtcaga aaaaagccga
    19621 atctttagct gttaaccttt atcaggcagg tcaagatttt ttaatgctga atggtgattt
    19681 ttcaagctct ttactaaatc tttcacagct gaacataggc ttagaaggag tctatcagca
    19741 ggagaatgca gccttggcgt tgcaaacttt tcttcttttt atgggagaag gaaaggaagc
    19801 tgttgatgaa caggctgtaa gaaaggcctt ggaacagacc cattgggctg gtcgcttgga
    19861 gcgtattcgc ccacagattt acttggatgg tgctcataac ctccctgcct tgactcgctt
    19921 ggttgagttt atcaaagaaa aagagcagga aggctatcga cctcaaatcc tctttggatc
    19981 cttgaaacgt aaggattatc aagggatgtt gggttatctg actgaaaatt tacctcaagt
    20041 ggaactcaaa atgaccgact ttgactatca agggtctttg gacgagacag atgtaacagg
    20101 ttaccatgta attccctctt accgagaatt tatcagcagt ttcgaagaaa gggcagacgc
    20161 tcaagacttg ctgttcgtta cagggtctct ctattttatc tcagaagtac ggggctacct
    20221 gctggaccgt gagcagataa attgaccccc ttttttgaac ttgttatact aggggaattg
    20281 ctggttagag aaaatttctc taaattggta gcagaaagga aattcatcat gaaattaaaa
    20341 agattcacac tttctcttgc ttctctagca agttttagtc tcttagtagc ttgttcacaa
    20401 agagctcaac aggttcaaca gcctgttgct cagcagcagg tccaacagcc tgctcaacaa
    20461 cctgctcaac agaataccaa tactgcaaat gcaggaggta accaaaatca agcggctcca
    20521 gtacaaaacc aacctgttgc tcaaccgacc gatattgatg ggacttatac tggtcaggat
    20581 gacggagacc gtatcacttt agtggtaact ggaacgactg gtacatggac tgagctcgaa
    20641 tctgacgggg atcagaaagt caaacaggtt acatttgatt cagcaaatca acgcatgatt
    20701 attggcgatg atgtcaaaat ttacactgta aacggtaatc aaatcgtcgt agatgatatg
    20761 gatagagacc catcggacca aatcgtttta actaaataag actatgcaag tagaaagggc
    20821 tggatttttc agccttttta cttttaccta gaaaataatc ataaatactt gccttctacc
    20881 gaatacctgc gttatactag tatcaattac ttgtttttag cattcaaact atcaaggagg
    20941 ggatatgaaa tataggaaat tccagttatt gatgtccaag tatggcttta gtctttcgat
    21001 tatgctactt gaactttgtc ttgtttttgg tctctttctt tatttaggac gcatggctcc
    21061 cattttatgg attactgtcc tcattctact gagtatcatc acaatcattt cgatagtcaa
    21121 ccgtaatacg actcctgaga ataaggtaac ctggttgtta gtagcctttg taccagtatt
    21181 tggtcccttg ctctatctga tgtttggtga aaggcgattg tccaaaaaag aaatcaaaca
    21241 actgaagaag ctaggctcta tgcatttcca agaagcaaat agccagctac taaaagagaa
    21301 attaaaagaa agtgacaagg cagcctatgg agtcatcaag tccttattga gtatggatac
    21361 caatgctgac atctatgatc aaactgcctc tacatttttt cctaacggag aagctatgtg
    21421 gaaaaagatg gtagaagatc ttaaaaaggc tgagaaattt attttcttgg aatattacat
    21481 tatagaagaa ggtttgatgt ggaatcgcat actagatata ctagagcaaa aggtagctca
    21541 gggtgtagag gttaagatgc tctatgatga tatcggctgt atggctactt taacaggaga
    21601 ttatgcacat cgacttcgtc agctgggcat cgaggcccat aaattcaata aagttattcc
    21661 tcgtttgaca gtggcttata ataacagaga tcatagaaaa atattgattg ttgatggtca
    21721 gatagcctat actggtgggg tcaatctggc agatgagtac attaaccacg tcgagagatt
    21781 tggttattgg aaggatagtg gaattcgctt agacggacta gcagtaaaag ctctgacacg
    21841 cttatttttg accacttggt acattaatcg aggagaaatt agtgattttg atcaatatca
    21901 tttagaaaat cattctatcc cgagtgacgg tttaaccatt ccatacggaa gtggacccaa
    21961 gccaattttt cgagcgcagg tagggaaaaa agtttatcag agtttaatca atcaagcaac
    22021 agaatcggtc tatattacga caccttattt gattatagat tatgatttaa cagagacaat
    22081 caaaaatgca gctatgagag gggtcgatgt tcgaattatc accccttaca taccagataa
    22141 gaagttcatt cagttagtca cgagaggagc ttatcccgac cttctttctg ctggtgttcg
    22201 gatttatgag tatagtccag gttttattca tagtaagcag atgttggtag acgaagattt
    22261 tgcggtggtg gggacaatca atctcgacta ccggagcttg gtacaccatt atgaaaatgc
    22321 agtcttactc tataaaactc cttctataag ggaaatcgcc cgagattttc gaaatatatt
    22381 tgcagattct caggaagtct atcctcattc tatcaaaacg agctggtatc aaaagcttgt
    22441 aaaagaaatc gcccagctat tcgcccctat cttataagaa atctagaact taggatacaa
    22501 accagaccta tttttcttgt cttttacgaa tagaaagaaa gaggagggga attcatgcta
    22561 actaaggaag aagtgaatga tatgattgag ttcaaacaga cacatttaca ccgctttcgg
    22621 gaaattgaaa cctttgtgaa actatgcaaa aaatcactca aacagccatc gcaagctgac
    22681 aatcctagga ctttttgata tactaagaca gataaattga acaggagaaa cgatatgagt
    22741 gtgtatggta gagtagaaga agttcataag gagaatcgtg aacctctaga ataccaaatc
    22801 gaacaagaat cgcatcatcg tgaatcaagt cgtcttcctt tggtgaaaat tttactatgg
    22861 agtacgcttg taacggggat aactctagga gtgccgctat tactcgactt aatgagtgca
    22921 caagaagtgc aggattttta tgcaggttgg gcgcttcatc agacagggaa gatttacagc
    22981 gactattatg gaagtcaagg tttgctttat tatttgctga cttacgtgag tcagggcgga
    23041 tttttctttg ccatctttga gtggttagcc ttggtagcag gaggattttt cctttttaga
    23101 tcagcggaca ccttgacaga gcaaggagac caagctggac atctggtgac tattttttac
    23161 atgctagtta caggtcttgc ttttggtgga ggctatgcga ctcttttagc gcttcctttc
    23221 ttattcgcag cctttagttt agttgcggct tacctaagca atccaagcca tgataaggga
    23281 tttgtacgga ttgggctagc tttggcaggc ggatttttct ttgctccctt atcatcgctc
    23341 ctgtttattg ctgtagtgag tttaggcttg ttggtcttta accttgggca tagacgtttt
    23401 gtgcatgggt tttatcagtt tcttgcagtg gctttaggtt tttcacttgt cttttatcca
    23461 actgcctact atagtgctgc aacaggaagt tttggggatg cgattagtgg tattcgttat
    23521 cctattgaca gtattcgctt tgattttact tctaaaattt tagagaatat gtttttttat
    23581 ggcttgttgt cccttggttt gggatttgtg gtttgtatct ttttaggtct ctttcaatcc
    23641 aaacccttta aactatacgt catttcggtt cctgcaagtc ttgtggtaat tttaggtttg
    23701 attttacttt tcttttcaca agagcctctg cacgcttctt atttgatggt cgtcttccct
    23761 gttttcctac ttttattggt aaccaatatt aagagtcaac agagggggcg tagtgctaga
    23821 agaagccgaa gagaaacgcc agttagccta tggagtcgtt tcttcaaagg aaatctatat
    23881 ctgctagttt ttgggtttgt ctatcttttg tctgttcctt ttttgatgaa gtttgtcctt
    23941 tatccagtac cttatcaaga acgtaatcgt cttgctgatt tggtaaaaga ggagacaaat
    24001 acggaagatg ctatctatgc atgggatgat actgcgactc tttatcgtaa gagtgagcgc
    24061 ttgtcgccat cggcgatttt gtccccgttg cactatacag caactgagga aaatcgtaat
    24121 aagttactta atgacttgaa agaaaaacaa cctaaggtga ttgtggtaaa tgacaaggtg
    24181 gtagtctggt ctgaagtgga aacactctta aaagaaaatt accaacaagt aaagactgat
    24241 tactcagagt ttaaagtcta taaaattaaa taaccaaatc aatatcttgt gtatttttaa
    24301 aaattttagg atttttaaca caagatattg atttttcttt ttagagtggt ataatacttt
    24361 ttagaaagaa cattttagaa aagagcatgc gtatgattgc actagaagaa aaaattacaa
    24421 ttttgccaac tctcttcgtc gagaaacgag atgggagacg tgttgtattt gatgtggaca
    24481 agattgacaa ggctctccac aaggcggctg acaaggttat ggatgtgaca cccctggttg
    24541 aaaaacgcct caatgatctg actgagcgaa ttattacaga aattcatagt cgctttccac
    24601 agggaattaa gatttacgaa attcaaaata tcgtagaaca tgaactcctt gaagccaaag
    24661 aatatgcgct ggctgaggag tatattactt atcggacaca gagggatttt gagcgctcaa
    24721 aagcgacgga tatcaacttt agtattcata aacttctcaa caaagaccag acagttgtca
    24781 atgaaaatgc taataaagac agtgatgtct ttaacactca gcgtgatttg acagcaggga
    24841 ttgttgggaa atcaatcgga ctgcaaatgc ttcctaagca cgtagccaat gcccaccaaa
    24901 agggggatat ccactatcac gatttggact acagtcccta tacccctatg accaactgct
    24961 gtttggttga ttttaagggt atgttggaaa atggttttaa gattggaaat gcagaggtag
    25021 agagtcccaa gtctatccag actgcgacag cacagatttc tcaaatcatt gccaacgttg
    25081 cttctagcca gtacggtggc tgttcagctg accgtatcga tgaaattttg gcgccttatg
    25141 cagagaagaa ctatcaaaaa catctcaaag atgcagaaga gtgggtattg tctgaaaaac
    25201 gggaagatta cgcttggaag aaaacgcaaa aggacatcta cgatgccatg caatctcttg
    25261 agtatgaaat caatactctc ttcacttcaa atggacaaac accttttact tcgttaggtt
    25321 ttggtctggg aaccagtcgt tttgaacgag aaattcaaaa agctatttta aacattcgca
    25381 tcaagggtct tggttcagaa caccgtacgg ctatctttcc taaacttatt ttcactctga
    25441 aaagaggcct taatttagag gaaggaactc ccaactacga catcaagcag ttggctcttg
    25501 agtgtgcaac caaacggatg tatccagatg ttttatctta cgataagatt gttgacttga
    25561 caggatcctt caaggtgcct atgggttgcc gttctttcct ccaaggatgg aaggatgaaa
    25621 atggtgtaga agtcaattca ggtcgcatga atctgggtgt tgtgacggtt aatctgcctc
    25681 gtattgctct tgagtctgaa ggtgatatga ataagttctg ggaaatcttc aacgagcgaa
    25741 tgaatatcgc agaagatgct cttgtttacc gtgtcgaacg cactaaagag gcgacaccag
    25801 caaatgctcc tattctttat cagtacggtg cttttggcca tcgtctaggt aaagaagaaa
    25861 gtgttgacca gctctttaag aatcgtcgtg cgaccgtttc gctgggctat atcggcttgt
    25921 atgaagtagc gacagttttc tttggtaaca gctgggaaag taatccagat gctaaggaat
    25981 tcacgctaga catcattcac gatatgaaac gccgtgtaga agagtggtca gaccaatatg
    26041 gctaccattt ctctatctac tcaacaccat ccgaaagtct gacagaccgt ttctgccgac
    26101 tagatataga caagtttggc tctattcctg atatcacaga caaggaatac tacaccaact
    26161 ctttccacta cgatgttcgt aaaaatccaa caccgtttga aaaattggac tttgagaaag
    26221 tctatccaga agcaggtgcg tcaggtggtt tcatccatta ttgtgagtat ccagtccttc
    26281 agcaaaatcc aaaggccttg gaagctgtct gggattatgc ttatgaccgt gtaggctatc
    26341 taggcaccaa tactccgatt gaccgttgct acaagtgtga ctttgaaggg gattttgaac
    26401 caactgagag agggtttgct tgtccaaact gtggcaatag cgatcctaaa acagtagacg
    26461 ttgttaaacg gacttgtggc tatcttggca atcctcaagc aagaccgatg gtcaacgggc
    26521 gtcacaagga aatcgctgcg cgtgtcaaac atatgaatgg ttcaacgatt aaaatagctg
    26581 ggcatcaagt aacaaattag aaagaaatga aatggggaaa tatcaactag acgataaggg
    26641 gcgcgcacaa gtgacccgtt atcacgagaa atactctaaa ggtggagctg gtaagaaaga
    26701 acgcttgctt agcttcagag aacaattttt aaacaagaac aagaaaaaat aaaagtgaga
    26761 gccagctctc gcttttctca tagtgggagg taaggatgga attacgcaga ccaagattag
    26821 cggataagaa agctgtttta gatatgatga cagagtttga aaagagccaa tcagcccatg
    26881 atggaggatt ttgggataca gagaactttg tgtatgaaga gtggttggaa agcaatcagg
    26941 aacaggaaat ggggattaat ctgcctgaag gatgggttcc tgcaattcag ttagtggctt
    27001 tttctgagaa aggtcaagca gttggatttc ttaatctccg gttgcgcctc agtaactttc
    27061 tactagaaga aggtgggcac attggctact ccatccgtcc atctgaaaga ggcaagggtt
    27121 atgcaaaaga gactctccgt cagggcttgc aagttgctaa ggaaaagaac atcaagaaag
    27181 ctctggtgac ctgtagcgtg aataatcctg ctagcagagc agtcattcta gcaaatggtg
    27241 gaatatttga ggatgctcac aatggagtcg agcgttattg gatagaggta gcgaatgaat
    27301 aatccaaaac cacaagaatg gaaaagcgag gaacttagtc aaggtcgtat cattgactac
    27361 aaggccttta actttgtgga cggcgaaggc gtgcgcaact ctctctatgt atcaggctgt
    27421 atgtttcact gcgagggatg ttataatgtt gcgacttggt cttttaatgc tggcattccc
    27481 tatacagcag aattagaaga gcagatcatg gcagaccttg cccaacccta tgttcaaggc
    27541 ttgactttgc tgggagggga accttttctc aatactggca ttctcttgcc tctagttaaa
    27601 cgcatccgaa aggaattgtc agacaaggac atttggtcct ggacgggcta cacttgggaa
    27661 gaaatgatgt tggaaactcc agataaactg gaactcttat cattgattga cattcttgtc
    27721 gatggacgat acgatcgaac taagagaaat ctcatgctcc agtttcgagg ttcgtccaac
    27781 caacgaatta tcgatgtgca aaaatcgctc aaaagtgggc aagtagtgat ttgggacaag
    27841 ctcaatgacg gaaaagaaag ctatgaacag gtgaagagag aatgaagaaa aaagacttag
    27901 tagaccaact agtctcagag atcgagacgg ggaaagtcag gacactggga atatacggtc
    27961 atggagcttc aggtaaatca acctctgcac aggaattgta ccaagcttta gattctacta
    28021 cagtaaattt gctagaaaca gatccctata tcacctcagg acgccatctg gtagtaccca
    28081 aggacgcgcc gaatcaaaag gtgacagccg gtctgccagt ggcgcatgaa ctggagagtt
    28141 tgcagagaga tatccttgcc ttgcaggcga gtatggatgt cttgacaatt gaagaacctt
    28201 ggaaggctag tgaggtcttg tctggagcca aaccaatttt gattgtcgaa gggatgtctg
    28261 ttggctttcg acccaaggaa ctctttgaaa aaaccatctg tttctacacg gatgaggaga
    28321 ccgaattaaa gcgacgcctt gctagagata cgactgtgag aaatcgtgat gcatccttta
    28381 tattggctag ccatcagatg agacgggagc agtatctgcg atactataaa gaaactgagt
    28441 ctaaggcgga tatcttagtg gatcaatcag aagataaatt tgatgtcaag aggacttaac
    28501 ttatgtatag aagaaatata gaagaaaatc cctaatttta gaaagaaaaa gtaggaaaac
    28561 agtttcatcc caaaaaaacg aaaaaaccta acaaatccct tgcaatcgca ggggatttgt
    28621 gttattctat tatggtgctg taaattacag ccttagtttt gatgcaagag gttgcgacac
    28681 gctcggttgc attgccacgc aacaccgtgt cggttttctt gtggagctag cctattatct
    28741 taaatagacg aaaaggagaa aaagatggca aacaaaaaaa tccgtatccg tttgaaagct
    28801 tacgaacacc gtacgcttga cacagcggct gcaaaaatcg tagaatcagc tactcgtaca
    28861 ggtgcacaag ttgcgggtcc aatcccactt ccaactgaac gtagcctcta cacaatcatt
    28921 cgtgcgactc acaaatacaa agactctcgc gaacaatttg aaatgcgtac acacaaacgt
    28981 ttgatcgata tcgttaaccc aactcaaaaa acagttgatg ccttgatgaa attggatctt
    29041 ccaagtggtg taaacgtaga aatcaaactt taatctaaaa tataaaagag cagaggctgg
    29101 tgtttcaatc taattgaaca cgggctaaac tcggtgtgaa aaagataaac ttcctagtgt
    29161 ctgctagaca ctgcgtcagt ttcctatttt caagttgagt ttgacgccct ttgtatctta
    29221 gacttgagca taaaaaacgc tcgttaaaaa ctttttgaat aaaaaatata gaaaaggaac
    29281 tattttctca tgacaaaagg aatcttaggg aaaaaagtgg gaatgactca aatcttcact
    29341 gaagctggcg aattgatccc tgtaacagtt attgaagcaa ctccaaacgt tgttcttcaa
    29401 gttaaaactg ttgaaacaga cggatacaac gctatccaag ttggtttcga tgacaaacgc
    29461 gaagtattga gcaacaaacc tgctaaagga catgtagcga aagctaacac ggctcctaag
    29521 cgcttcattc gtgaattcaa aaacgttgaa ggcttggaag ttggtgctga aattacagtt
    29581 gaaacattcg cagctggaga cgttgttgac gtaactggta cttctaaagg taaaggtttc
    29641 caaggtgtta tcaaacgcca cggacaatca cgtggaccaa tggctcacgg ttctcgttac
    29701 caccgtcgtc caggttctat gggacctgtt gcacctaacc gcgtattcaa aggtaaaaac
    29761 cttgcagggc gtatgggtgg cgaccgcgta acaattcaaa accttgaagt tgtacaagtt
    29821 gttccagaaa agaacgttat ccttatcaaa ggtaacgtac caggtgctaa gaaatctctt
    29881 atcactatca aatcagcagt taaagctggt aaataataaa gaaaggggaa atcagtcaca
    29941 atggcaaacg taacattatt tgaccaaact ggtaaagaag ctggccaagt tgttcttagc
    30001 gatgcagtat ttggtatcga accaaatgaa tcagttgtgt ttgatgtaat catcagccaa
    30061 cgcgcaagcc ttcgtcaagg aacacacgct gttaaaaacc gctctgcagt atcaggtggt
    30121 ggacgcaaac catggcgtca aaaaggaact ggacgtgctc gtcaaggttc tatccgctca
    30181 ccacaatggc gtggtggtgg tgttgtcttc ggaccaactc cacgttcata cggctacaaa
    30241 cttccacaaa aagttcgtcg cctagctctt aaatcagttt actctgaaaa agttgctgaa
    30301 aacaaattcg tagctgtaga cgctctttca tttacagctc caaaaactgc tgaatttgca
    30361 aaagttcttg cagcattgag catcgattct aaagttcttg ttatccttga agaaggaaat
    30421 gaattcgcag ctctttcagc tcgtaacctt ccaaacgtga aagttgcaac tgctacaact
    30481 gcaagtgttc ttgacatcgc aaatagcgac aaacttcttg tcacacaagc agctatctct
    30541 aaaatcgagg aggttcttgc ataatgaatt tgtatgatgt tatcaaaaaa cctgtcatca
    30601 ctgaaagctc aatggctcaa cttgaagcag ggaaatatgt atttgaagtt gacactcgtg
    30661 cacacaaact tttgatcaag caagctgttg aagctgcttt cgaaggtgtt aaagttgcca
    30721 atgttaacac aatcaacgta aaaccaaaag ctaaacgtgt tggacgttac actggtttta
    30781 ctaacaaaac taaaaaagct atcatcacac ttacagctga ttctaaagca atcgagttgt
    30841 ttgctgctga agctgaataa tctaaggagg aaatatcgtg ggaattcgtg tttataaacc
    30901 aacaacaaac ggtcgccgta atatgacttc tttggatttc gctgaaatca caacaagcac
    30961 tcctgaaaaa tcattgcttg ttgcattgaa gagcaaggct ggtcgtaaca acaacggtcg
    31021 tatcacagtt cgtcaccaag gtggtggaca caaacgtttc taccgtttgg ttgacttcaa
    31081 acgtaataaa gacaacgttg aagcagttgt taaaacaatc gagtacgatc caaaccgttc
    31141 tgcaaacatc gctcttgtac actacactga cggtgtgaaa gcatacatca tcgctccaaa
    31201 aggtcttgaa gtaggtcaac gtatcgtttc aggtccagaa gcagatatca aagtcggaaa
    31261 cgctcttcca cttgctaaca tcccagttgg tactttgatt cacaacatcg agttgaaacc
    31321 aggtcgtggt ggtgaattgg tacgtgctgc tggtgcatct gctcaagtat tgggttctga
    31381 aggtaaatat gttcttgttc gtcttcaatc aggtgaagtt cgtatgattc ttggaacttg
    31441 ccgtgctaca gttggtgttg tcggaaacga acaacatgga cttgtaaacc ttggtaaagc
    31501 aggacgtagc cgttggaaag gtatccgccc aacagttcgt ggttctgtaa tgaaccctaa
    31561 cgatcaccca cacggtggtg gtgaaggtaa agcaccagtt ggtcgtaaag caccatctac
    31621 tccatggggc aaacctgctc ttggtcttaa aactcgtaac aagaaagcga aatctgacaa
    31681 acttatcgtt cgtcgtcgca acgagaaata atattaaact agtcgcttaa gcaactagta
    31741 aatccgccag ctcggtagcg ctccatagga gtgcaagccg ctgtggtaca acatttaaag
    31801 gagaaaatat aaaaatggga cgcagtctta aaaaaggacc tttcgtcgat gagcatttga
    31861 tgaaaaaagt tgaagctcaa gctaacgacg aaaagaaaaa agttattaaa acttggtcac
    31921 gtcgatcaac gatcttccca agtttcattg gttacactat tgcagtttat gacggacgta
    31981 aacacgtacc tgtttacatc caagaagaca tggtaggcca caaacttggt gaatttgcac
    32041 caactcgtac ttacaaaggt cacgctgcag acgacaagaa aacacgtaga aaataaggag
    32101 aacataaatg gcagaaatta cttcagctaa agcaatggct cgtacagtac gtgtttcacc
    32161 tcgtaaatca cgtcttgttc ttgataacat ccgtggtaaa agcgtagccg atgcaatcgc
    32221 aatcttgaca ttcactccaa acaaagctgc tgaaatcatc ttgaaagttt tgaactcagc
    32281 tgtagctaac gctgaaaaca actttggttt ggataaagct aacttggtag tatctgaagc
    32341 attcgcaaac gaaggaccaa ctatgaaacg tttccgtcca cgtgcgaaag gttcagcttc
    32401 accaatcaac aaacgtacag ctcacatcac tgtagctgtt gcagaaaaat aaggaggtaa
    32461 aatcgtgggt caaaaagtac atccaattgg tatgcgtgtc ggcatcatcc gtgattggga
    32521 tgccaaatgg tatgctgaaa aagaatacgc ggattacctt catgaagatc ttgcaatccg
    32581 taaattcgtt caaaaagaac ttgctgacgc agcagtttca actattgaaa tcgaacgcgc
    32641 agtaaacaaa gttaacgttt cacttcacac tgctaaacca ggtatggtta tcggtaaagg
    32701 tggtgctaac gttgatgcac tccgtgcaaa acttaacaaa ttgactggaa aacaagtaca
    32761 catcaacatc atcgaaatca aacaacctga tttggatgct caccttgtag gtgaaggaat
    32821 tgctcgtcaa ttggagcaac gtgttgcttt ccgtcgtgca caaaaacaag caatccaacg
    32881 tgcaatgcgt gctggagcta aaggaatcaa aactcaagta tcaggtcgtt tgaacggtgc
    32941 agatatcgcc cgtgctgaag gatactctga aggaactgtt ccgcttcaca cacttcgtgc
    33001 agatatcgat tacgcttggg aagaagcaga tactacatac ggtaaacttg gtgttaaagt
    33061 atggatctac cgtggtgaag ttcttccagc tcgtaaaaac actaaaggag gtaaataacc
    33121 aatgttagta cctaaacgtg ttaaacaccg tcgtgagttc cgtggaaaaa tgcgcggtga
    33181 agcaaaaggt ggaaaagaag tagcattcgg tgaatacggt cttcaagcta caactagcca
    33241 ctggatcact aaccgccaaa tcgaagctgc tcgtatcgcc atgactcgtt acatgaaacg
    33301 tggtggtaaa gtttggatta aaatcttccc acacaaatca tacactgcta aagctatcgg
    33361 tgtgcgtatg ggatctggta aaggggcacc tgaaggttgg gtagcaccag ttaaacgtgg
    33421 taaagtgatg ttcgaaatcg ctggtgtatc tgaagagatt gcacgtgaag cgcttcgact
    33481 tgctagccac aaattgccag ttaaatgtaa attcgtaaaa cgtgaagcag aataaggaga
    33541 aggcatgaaa cttaatgaag taaaagaatt tgttaaagaa cttcgtggtc tttctcaaga
    33601 agaactcgcg aagcgcgaaa acgaattgaa aaaagaattg tttgaacttc gtttccaagc
    33661 tgctactggt caattggaac aaacagctcg cttgaaagaa gttaaaaaac aaatcgctcg
    33721 tatcaaaaca gttcaatctg aagcgaaata atagactagg gaaggagaaa tttcaatgga
    33781 acgcaataat cgtaaagttc ttgttggacg tgttgtatct gacaaaatgg acaagacaat
    33841 cacagttgta gttgaaacaa aacgtaacca cccagtctat ggtaaacgta ttaactactc
    33901 taaaaaatac aaagctcatg atgaaaacaa tgttgccaaa gaaggcgata tcgtacgtat
    33961 catggaaact cgcccgcttt cagctacaaa acgtttccgt cttgtagaag ttgttgaaga
    34021 agcggtcatc atctaatcaa acctgaaagg agaaaactga aatgattcaa acagaaactc
    34081 gtttgaaagt cgcagacaac agcggtgctc gcgaaatctt gactatcaaa gttcttggtg
    34141 gttcaggacg taaatttgca aacatcggtg atgttatcgt ggcatctgta aaacaagcta
    34201 ctcctggtgg tgcggttaaa aaaggtgacg ttgttaaagc agttatcgtt cgtactaaat
    34261 caggtgctcg tcgtgctgat ggttcataca tcaaatttga cgaaaacgca gcagttatca
    34321 tccgtgaaga caaaactcct cgcggaacac gtatctttgg cccagttgca cgtgaattgc
    34381 gtgaaggtgg cttcatgaag atcgtgtcac ttgctccaga agtactttaa tttttaggaa
    34441 caaactagtc ccctagcttc aagctagggt gcccttatgg gcgtaagaaa aatcaaggag
    34501 aaacctaatg tttgtaaaaa aaggcgacaa agttcgcgta atcgctggta aagataaggg
    34561 aacagaagct gttgtcctta ctgcccttcc aaaagtaaac aaagttatcg ttgaaggtgt
    34621 taacattgtt aagaaacacc aacgtccaac taacgagctt cctcaaggtg gtatcatcga
    34681 gaaagaagca gctatccacg tatcaaacgt tcaagttttg gacaaaaatg gtgtagctgg
    34741 tcgtgttggt tacaaatttg tagacggtaa aaaagttcgc tacaacaaaa aatcaggcga
    34801 agtgcttgat taatcacgaa ggaaaggaga agtataatgg caaatcgttt aaaagaaaaa
    34861 tatcttaatg aagtagttcc tgctttgaca gaacaattca actactcatc agtgatggct
    34921 gtgcctaaag tagataagat tgttttgaac atgggtgttg gtgaagctgt atcaaacgct
    34981 aaaagccttg aaaaagctgc tgaagaattg gcacttatct caggtcaaaa accacttatc
    35041 actaaagcta aaaaatcaat cgccggcttc cgtcttcgtg aaggtgttgc gatcggtgca
    35101 aaagttaccc ttcgtggtga acgtatgtac gaattcttgg ataaattggt atcagtttca
    35161 cttccacgtg tacgtgactt ccacggtgtc ccaacaaaat catttgatgg acgcgggaac
    35221 tacacacttg gtgtgaaaga acaattaatc ttcccagaaa tcaacttcga tgacgttgac
    35281 aaaactcgtg gtcttgacat cgttatcgta acaactgcta acactgacga agagtcacgt
    35341 gcattgctta caggccttgg aatgcctttt gcaaaataat ataggaggta aatctaatgg
    35401 ctaaaaaatc aatggtagct agagaggcta aacgccaaaa aattgttgac cgttatgctg
    35461 aaaaacgtgc tgcattaaag gcggcagggg actacgaagg tttatctaaa ttacctcgca
    35521 acgcttcacc gactcgttta cataatcgtt gtagagttac ggggcgccca cattcagttt
    35581 accgcaaatt tggtctgagt cgtatcgctt ttcgcgaact tgcgcataaa ggtcaaattc
    35641 ctggtgtaac aaaagcatct tggtaattta agatatcaag ggcgtcaaaa ctccaagtaa
    35701 aaataggaaa cttgacgaag aaactaaagt ttctaggaaa gtttatcttt ttcacacaga
    35761 gtttagcccg ggttcaattg ggcttgccaa tttgaacacg agctacagct ttggcaaaaa
    35821 agaccaattt gctttggagc attgcttctg cattaaattg tctatttttg ctcgtgctgt
    35881 tacgctcttt gtatcatgta ttaactagca agtgcaactt gcaaactact agtaagagga
    35941 gaaaaacaaa atggttatga ctgacccaat cgcagacttc ctaactcgta ttcgtaatgc
    36001 taaccaagct aaacacgaag tacttgaagt acctgcatca aacatcaaaa aagggattgc
    36061 tgaaatcctt aaacgcgaag gttttgtaaa aaacgttgaa atcatcgaag atgacaaaca
    36121 aggcgtcatc cgtgtatttc ttaaatacgg accaaatggt gaaaaagtta tcactaactt
    36181 gaaacgtgtt tctaaaccag gacttcgtgt ctacaaaaaa cgtgaagacc ttccaaaagt
    36241 tcttaacgga cttggaattg ccatcctttc aacttctgaa ggtttgctta ctgataaaga
    36301 agcacgccaa aagaatgttg gtggtgaggt tatcgcttac gtttggtaaa atcaagatac
    36361 aaagctcgta aagaacaaag caaaattagg aagttggaga agtttgttta caaacaagcc
    36421 aacttatcta ttttgcacag ttcttagagc gtgttcagtt cagctcttga actaaataag
    36481 tatctgaacc ccgtgaaaac tggccgtttt ggcctgacaa tttaacagga gaaaataaac
    36541 atgtcacgta ttggtaataa agttatcgtg ttgcctgctg gtgttgaact cgctaacaat
    36601 gacaacgttg taactgtaaa aggacctaaa ggagaactta ctcgtgagtt ctcaaaagat
    36661 attgaaatcc gtgtggaagg tactgaagta actcttcacc gtccaaacga ttcaaaagaa
    36721 atgaaaacta tccacggaac tactcgtgcc cttttgaaca acatggttgt tggtgtatca
    36781 gaaggattca agaaagaact tgaaatgcgt ggggttggtt accgtgcaca gcttcaagga
    36841 tcaaaacttg ttttggctgt tggtaaatct catccagacg aagttgaagc tccagaagga
    36901 attacttttg aacttccaaa cccaacaaca atcgttgtta gcggaatttc aaaagaagta
    36961 gttggtcaaa cagctgctta cgtacgtagc cttcgttcac cagaaccata taaaggtaaa
    37021 ggtatccgtt acgttggtga attcgttcgc cgtaaagaag gtaaaacagg taaataatgt
    37081 tgagtggttg atcatcaacc accaacctat tttccaactt tgtgcatagc acacgattta
    37141 aaactaaaga ggtgaaaact gtgatttcaa aaccagataa aaacaaactc cgccaaaaac
    37201 gccaccgtcg cgttcgcgga aaactctctg gaactgctga tcgcccacgt ttgaacgtat
    37261 tccgttctaa tacaggcatc tacgctcaag tgattgatga cgtagcgggt gtaacgctcg
    37321 caagtgcttc aactcttgat aaagaagttt caaaaggaac taaaactgaa caagccgttg
    37381 ctgtcggtaa actcgttgca gaacgtgcaa acgctaaagg tatttcagaa gtggtgttcg
    37441 accgcggtgg atatctatat cacggacgtg tgaaagcttt ggctgatgca gctcgtgaaa
    37501 acggattgaa attctaatag gaggacacta gaaaatggca tttaaagaca atgcagttga
    37561 attagaagaa cgcgtagttg ctgtcaaccg tgttacaaaa gttgttaaag gtggacgtcg
    37621 tcttcgtttc gcagctcttg ttgttgttgg tgaccacaat ggtcgcgtag gatttggtac
    37681 tggtaaagct caagaagttc cagaagcaat ccgtaaagca gtagatgatg ctaagaaaaa
    37741 cttgatcgaa gttcctatgg ttggaacaac aatcccacac gaagttcttt cagaattcgg
    37801 tggagctaaa gtattgttga aacctgctgt agaaggttct ggagttgccg ctggtggtgc
    37861 agttcgtgcc gttgtggaat tggcaggtgt ggcagatatt acatctaaat cacttggttc
    37921 taacactcca atcaacattg ttcgtgcaac tgttgaaggt ttgaaacaat tgaaacgcgc
    37981 tgaagaaatt gctgcccttc gtggtatttc agtttctgat ttggcataag aaaggggata
    38041 aaatggctca aattaaaatt actttgacta agtctccaat cggacgcatt ccatcacaac
    38101 gtaaaactgt tgtagcactt ggacttggca aattgaacag ctctgttatt aaagaagata
    38161 acgctgctat ccgtggtatg attacagcag tatctcactt agtaacagtt gaagaagtaa
    38221 actaatgaag ttttagggga tgtgcactgt accatcccct aaaactagat atagtcatct
    38281 atgatgacat cgtataggcg agttgatggg ggagacaacc ttttctccct tatcggcgct
    38341 agcattttac aaaagaggag aaaataaaaa tgaaacttca tgaattgaaa cctgcagaag
    38401 gttctcgtaa agtacgtaac cgcgttggtc gtggtacttc atcaggtaac ggtaaaacat
    38461 ctggtcgtgg tcaaaaaggt caaaaagctc gtagcggtgg cggagttcgc cttggttttg
    38521 aaggtggaca aactccattg ttccgtcgtc ttccaaaacg tggattcact aacatcaacg
    38581 ctaaagaata cgcaattgtg aaccttgacc aattgaacgt ctttgaagat ggtgctgaag
    38641 taactccagt tgttcttatc gaagcaggaa ttgttaaagc tgaaaagtca ggtattaaaa
    38701 ttcttggtaa cggtgagttg actaagaaat tgactgtgaa agcagctaaa ttctctaaat
    38761 cagctgaaga agctatcact gctaaaggtg gttcagtaga agtcatctaa gagaggtgac
    38821 ctatgttttt taaattatta agagaagctc ttaaagtcaa gcaggttcga tcaaaaattt
    38881 tatttacaat ttttatcgtt ttggtctttc gtatcggaac tagcattaca gttcctggtg
    38941 tgaatgccaa tagcttgaat gctttaagtg gattatcctt cttaaacatg ttgagcttgg
    39001 tgtcggggaa tgccctaaaa aacttttcga tttttgccct aggagttagt ccctatatca
    39061 ccgcttctat tgttgtccaa ctcttgcaaa tggatatttt acccaagttt gtagagtggg
    39121 gtaaacaagg ggaagtaggt cgaagaaaat tgaatcaagc tactcgttat attgctctag
    39181 ttctcgcttt tgtgcaatct atcgggatta cagctggttt taataccttg gctggagctc
    39241 aattgattaa aactgcttta actccacaag tttttctgac gattggtatc atcttaacag
    39301 ctggtagtat gattgtcact tggttgggtg agcaaattac agataaggga tacggaaacg
    39361 gtgtttccat gattatcttt gccgggattg tttcctcaat tccagagatg attcagggca
    39421 tctatgtgga ctactttgtg aacgtcccaa gtagccgtat cacttcatct atcattttcg
    39481 taatcatttt gattattact gtattgttga ttatttactt tacaacttat gttcaacaag
    39541 cagaatacaa aattccaatc caatatacta aggttgcaca aggtgctcca tctagctctt
    39601 accttccgtt aaaggtaaac cctgctggag ttatccctgt tatctttgcc agttcgatta
    39661 ctgcagcgcc tgcggctatt cttcagtttt tgagtgccac aggtcatgat tgggcttggg
    39721 taagggtagc acaagagatg ttggcaacta cttctccaac tggtattgcc atgtatgctt
    39781 tgttgattat tctctttaca ttcttctata cgtttgtaca gattaatcct gaaaaagcag
    39841 cagagagcct acaaaagagt ggtgcctata tccatggagt tcgtcctggt aaaggtacag
    39901 aagaatatat gtctaaactt cttcgtcgtc ttgcaactgt tggttccctc tttcttggtg
    39961 tgatttccat tttaccgatt gcagctaaag atgtatttgg tctttctgat gttgttgcct
    40021 ttggtggaac aagtctcttg atcattatct ctacaggtat cgaaggaatc aagcaattgg
    40081 aaggttacct attgaaacgt aagtatgttg gtttcatgga cagaacagaa taaaagtatt
    40141 tactgaatca gtaaatactg agggagtgga ggtttaaact ctgacatttg taagagttgg
    40201 atctcccctc ttctattttg tttttaaata ggggtgaaaa gactttttgc ttctatttaa
    40261 aaataaaata aggagatcaa atcatgaatc ttttgattat gggcttacct ggtgcaggta
    40321 agggaactca agcagcaaaa atcgtagaac aattccatgt tgcacatatc tcaacaggtg
    40381 atatgttccg cgctgcaatg gcaaatcaaa ctgaaatggg tgttcttgct aagtcatata
    40441 ttgacaaggg tgaattggtt cctgacgaag ttacaaatgg aatcgtaaaa gaacgccttt
    40501 cacaagatga tattaaagaa acaggattct tattggatgg ttacccacgt acaattgaac
    40561 aagctcatgc cttggacaaa acattggctg aacttggcat tgaactagaa ggtattatca
    40621 atattgaagt gaaccctgac agcctcttgg aacgtttgag tggccgtatc atccaccgcg
    40681 taactggaga aactttccac aaggtcttta acccaccagt tgactataaa gaagaagatt
    40741 actaccaacg tgaagatgat aagcctgaga cagtaaaacg tcgtttggat gttaatattg
    40801 ctcaaggaga accaatcatt gctcactacc gtgccaaagg tttggttcat gacatcgaag
    40861 gtaatcaaga tatcaatgat gtcttctcag atattgaaaa agtattgaca aatttgaaat
    40921 aaagcgtttt tcacacttgc aaaaatccgc tacaaatgtt atactgaaat agtctgactt
    40981 ataattgttg tctctgtgtc tagaggcatc gaatcgaaat ttatggaggt gcttttgcgt
    41041 ggcaaaagac gatgtgattg aagttgaagg caaagtagtt gatacaatgc cgaatgcaat
    41101 gtttacggtt gaacttgaaa atggacatca gattttagca acagtttctg gtaaaattcg
    41161 taaaaactat attcgtattt tagcgggaga tcgtgttact gtcgaaatga gtccatatga
    41221 cttgacacgt ggacgtatca cttaccgctt taaataatcg aaaaacttgg agggataaga
    41281 aatgaaagta agaccatcgg tcaaaccaat ttgcgaatac tgtaaagtta ttcgtcgtaa
    41341 tggtcgtgtt atggtaattt gcccagcaaa tccaaaacac aaacaacgtc aaggataaga
    41401 tagaaaggag aaaacatggc tcgtattgct ggagttgata ttccaaatga caaacgcgta
    41461 gtaatctcat tgacttatgt ttatggtatc ggacttgcaa catctaagaa aattttggct
    41521 gctgctggaa tctcagaaga tgttcgtgta cgtgatctta catcagatca agaagatgct
    41581 atccgtcgtg aagtggatgc aatcaaagtt gaaggtgacc ttcgtcgtga agtaaacttg
    41641 aacatcaaac gtttgatgga aatcggttca taccgtggta tccgtcaccg tcgtggactt
    41701 cctgtccgtg gacaaaatac taaaaacaac gctcgcactc gtaaaggtaa agctgttgcg
    41761 attgctggta agaaaaaata atataggagg taaaagtctt ggctaaacca acacgtaaac
    41821 gtcgtgtgaa aaagaatatc gaatctggta ttgctcatat tcacgctaca tttaataaca
    41881 ctattgttat gattactgat gtgcatggta atgcaattgc ttggtcatca gctggtgctc
    41941 ttggtttcaa aggttctcgt aaatctacac cattcgctgc tcaaatggct tctgaagctg
    42001 ctgctaaatc tgcacaagaa cacggtctta aatcagttga agttactgta aaaggtccag
    42061 gttctggtcg tgagtcagct attcgtgcgc ttgctgccgc tggtcttgaa gtaacagcaa
    42121 ttcgtgatgt gactccagtg ccacacaatg gtgctcgtcc tccaaaacgt cgccgtgtat
    42181 aatcatcgca ttacactgct tttcgtttaa gagggagtaa ctaaatgatc gagtttgaaa
    42241 aaccaaatat aacaaaaatt gatgaaaata aagattatgg caagtttgta atcgaaccac
    42301 ttgaacgtgg ctacggtaca actcttggta actctcttcg tcgtgtactt ctagcttctc
    42361 taccaggagc agctgtgaca tctatcaaca ttgatggtgt gttacatgag tttgacacag
    42421 ttccaggtgt tcgtgaagac gtgatgcaaa tcattctgaa cattaaagga attgcagtga
    42481 aatcgtacgt tgaagacgaa aaaatcatcg aactggatgt tgaaggtcct gctgaagtaa
    42541 cagctggtga cattttgaca gatagcgata ttgaaattgt aaatccagat cattatctct
    42601 ttacaatcgg tgaaggttct tctctaaaag cgactatgac tgttaacagt ggtcgtggat
    42661 atgtacctgc tgatgaaaat aaaaaggata atgcaccagt tggaacactt gctgtagatt
    42721 ctatttatac accagttaca aaagtcaact atcaagtgga acctgctcgt gtaggtagca
    42781 atgatggttt cgacaaatta acccttgaaa tcttgacaaa tggaacaatt attccagaag
    42841 atgctttagg gctttcagca cgtattttga cagaacatct tgatttgttt acaaatctta
    42901 ctgagattgc taagtcaact gaagtgatga aagaagctga tactgaatct gacgaccgta
    42961 ttttagatcg tacgattgag gaactggact tgtctgtgcg ttcatacaac tgtttaaaac
    43021 gtgccggtat caatactgtg catgatttga cagaaaaatc tgaagcagag atgatgaaag
    43081 tacgaaatct tggacgcaag agtttggaag aagtgaaact caaactcatt gatttgggtc
    43141 ttggattaaa agataaataa aggaggaata catggcttac cgtaaactag gacgcactag
    43201 ctcacaacgt aaagcaatgc ttcgcgattt gacaactgac cttttgatca acgaatcaat
    43261 cgtgacaact gaagctcgtg ctaaagaaat ccgtaaaact gttgaaaaaa tgattactct
    43321 aggtaaacgt ggtgatttgc atgcacgtcg tcaagcagct gctttcgtac gtaatgaaat
    43381 cgcatctgaa aactatgatg aagcaactga taagtacact tctactacag cacttcaaaa
    43441 attgttctca gaaatcgcac ctcgttatgc tgaacgtaac ggtggataca ctcgtatcct
    43501 taaaactgaa ccacgtcgtg gtgatgcagc gccaatggcg atcatcgaat tagtataaaa
    43561 tcatcaattt tgttgagtgt tatgatgatg gagtcttgtg ctcttagtct agctctggtc
    43621 taccgctagg atttcggtcc tagcgggaac actcatcata agttgggata gtagacgctt
    43681 gtttacgaaa ttgttttttt cttaagaaca acttcgtaag caggcgtttt tgagtatttt
    43741 cgttagaatt atgctatact atttgaaaag aatcctgttt aatgttaagg tttcttattt
    43801 taagaagaat tggagtttgc ttatgaaagc gattataact gttgttggta aagataaatc
    43861 tggaattgtt gcaggtgttt ctggtaaaat tgcagaatta ggattgaata ttgacgatat
    43921 ctctcaaact gtcttggatg aatattttac gatgatggct attgtatcta gtgatgaaaa
    43981 gcaagatttt acctatcttc gtaatgaatt tgaagctttt gggcaaactt tgaatgtaaa
    44041 aatcaatatt cagagtgcag cgattttcga agctatgtat aatatctagg aggttatcat
    44101 ggatattaga caagttactg aaaccatcgc catgattgag gagcaaaatt tcgatatcag
    44161 aaccattacc atggggattt ctcttttgga ctgtatcgat ccagatatca atcgtgctgc
    44221 ggagaaaatc tatcaaaaaa ttacgacaaa ggcggctaat ttagtagctg ttggtgatga
    44281 aattgcggct gagttgggaa ttcctatcgt taataagcgt gtatcggtga cacctatttc
    44341 tctgattggg gcagcgacag atgcgacgga ctacgtggtt ctggcaaaag cgcttgataa
    44401 ggctgcgaaa gagattggtg tggactttat tggtggtttt tctgccttag tacaaaaagg
    44461 ttatcaaaag ggagatgaga ttctcatcaa ttccattcct cgcgctttgg ctgagacgga
    44521 taaggtctgc tcgtcagtca atatcggctc aaccaagtct ggtattaata tgacggctgt
    44581 ggcagatatg ggacgaatta tcaaggaaac agcaaatctt tcagatatgg gagtggccaa
    44641 gttggttgta ttcgctaatg ctgttgagga caatccattt atggcgggtg cctttcatgg
    44701 tgttggggaa gcagatgtta tcatcaatgt cggagtttct ggtcctggtg ttgtgaaacg
    44761 tgctttggaa aaagttcgtg gacagagctt tgatgtagta gccgaaacag ttaagaaaac
    44821 tgcctttaaa atcactcgta tcggtcaatt ggttggtcaa atggccagtg agagactggg
    44881 tgtggagttt ggtattgtgg acttgagttt ggcaccaacc cctgcggttg gagactctgt
    44941 ggcacgtgtc cttgaggaaa tggggctaga aacagttggc acgcatggaa cgacggctgc
    45001 cttggccctc ttgaacgacc aagttaaaaa gggtggagtg atggcctgta accaggtcgg
    45061 tggtttatct ggtgccttta tccctgtttc tgaggatgaa ggaatgattg ctgcagtgca
    45121 aaatggctct cttaatttag aaaaactaga agctatgacg gctatctgtt ctgttggatt
    45181 ggatatgatt gccatcccag aagatacgcc tgctgaaact attgcggcta tgattgcgga
    45241 tgaagcagca atcggtgtta tcaacatgaa aacaacagct gttcgtatca ttcccaaagg
    45301 aaaagaaggc gatatgattg agtttggtgg tctattagga actgcacccg ttatgagggt
    45361 taatggggct tcgtctgtcg acttcatctc tcgcggtgga caaatcccag caccaattca
    45421 tagttttaaa aattaagaaa ataggagaaa ttttaagttc tatttaagat tagatgtgta
    45481 tactataatc attaaataaa gacctcctaa tattatttga aacagataac actgaattag
    45541 tttgaatttg attttcatct aatatcttta tttaatgaac tcctaaactt tttcataata
    45601 atctccttca aaagtcgcct gtatgggtgg cttttatttt atcattcatg atataataga
    45661 agcaaacgga ggacggaaaa tggtaaaagt acgattgtat ttggtacgtc atggcaagac
    45721 catgtttaac acgattggtc gcgcgcaagg ttggagcgat actcccttaa ctgctgaagg
    45781 tgaacgaggg attcaagagt taggaatcgg tttgcgagaa tctgatctac agtttgagcg
    45841 cgcttattcg agtgattctg gtcgtaccat tcagaccatg ggaattatcc ttgaagaact
    45901 tggcttgcag gggaaaatcc cttatcgcat ggacaagcgt atcagagaat ggtgtttcgg
    45961 tagttttgat ggagcctatg atggcgatct tttcatgggc attattcctc gtatctttaa
    46021 tgtggaccac gttcaccaat tgtcttatgc tgaactggct gagggcttgg tagaggtcga
    46081 tacagctggt tgggctgaag gctgggaaaa actcagtggc cgaatcaagg aaggctttga
    46141 aatgattgca aaagaaatgg aagatcaagg tggaggtaac gcccttgttg tcagccatgg
    46201 aatgactatt ggaaccattg tttatctgat taatggcatg catccgcatg gtctagataa
    46261 tggtagcgtg acgattcttg aatatgagga cggtcagttt agggttgaag ttgtcggtga
    46321 ccgtagttac cgagagctag gacgtgagaa gatggaagaa ggctctattt aatcagtcta
    46381 gacttgcttg ccatgagcta gggatttgat aagaatatca agataagaaa aaacagccga
    46441 gggtactcct ttcggctgtt tttgatgtgg aaaactaaag tgtaatgcta ttgcttttag
    46501 agattttcat aaacaagagc aaggaaccta ctgttagaac agtcaggata gttgacaagg
    46561 ctgcggctac accgtaattt cctctgagaa cctctgtata aatagctaca gtcattgttc
    46621 ttgttttgac attgtagagg aggatagaag tagagagttt tgaaatcatt gtgacccaag
    46681 ataagatggc tccagaaatg ataccagata gcatcattgg agttgtaatc ttagcaaagg
    46741 tattgagacg actacttcct aagctttcag cagcttcttc aatacttggt gctatttgtt
    46801 gtaagctagc aacagatgag cgaatagtat aaggtaatct tctgacagat agagacataa
    46861 tcaagatgaa agcagtccct gtaatcataa gaaatccact tccaaataga ccagtattga
    46921 aggaagaaat gaaggcaatc cctagaacgg ttcctggtac aatataaggt accatactga
    46981 ggctgtcaat taagtttgta aacaaattcc gttttctaac ggctaggtag gagataaatg
    47041 tcgcaaatag aacaactaga actaaggcaa tcaaagggat acgaatggta ttgaaaatag
    47101 cagatcccat acgatggaaa gctaccttgt aactgtttgg agaataacct ttaacagata
    47161 ccatacctga tgtttttagg aaagaggtat aaattaagta gatttgaggt aaaacagaga
    47221 taaagataat tccgtagact gttgcataaa tggcagctat ttttcctttt gtagtttttt
    47281 taggctcaat tggatggagc agattcatgc tgaaactgta gcggtttgca atgtgttttt
    47341 ggataaggaa aattgccaag gcaatgataa tcgccataat tgcaaaagca gaatttcctc
    47401 caacctcgct aataaattgg gtataaatca ggacagggaa agtccgatat ccttcgccaa
    47461 tcaacatagg cgttccaaag tctgagaatg ctctcataaa tacaagcaag gagctgctag
    47521 taaggttgga actaggagag gtaaaacaac cgttacgata cgcttaaatc cgaaggaccc
    47581 ccatgctttc agctgcttca agtagagaat tgtcaatact gttcattgtt ccagcaacat
    47641 atagaaatac cagtgggaat agttgcagtg taaagacaag tacaattcct ttgaatccat
    47701 aaatatcgat agctggaaga tgaagggcat ttgtcaaaaa tttagtgatg accccatttc
    47761 gtcctagcaa gagaacccag gagtaggctc ctacgaaagg agctgacatg gaagcaatga
    47821 taatcaatat ttgtagaaat ttctccccct tgaagtcata catagagaag agataagcta
    47881 atagggttcc tacaactaag gaagtgacag tagcggtaat ggaaaccttg aaactgttga
    47941 ctagtgtctc agagtagtag actttactaa agaaagtgac aaaattagct agtgagaatt
    48001 atccttcatg tataagtgct tacttgagca cggtaatgat aggataaacg agaaagacaa
    48061 gataggtaag aaagatgaag aaagaggagg ctgtccaaat atttagtttt ttacattcca
    48121 tggttgactc cttttatcag gttttgggaa ccatctgcag aaaagatgtt taatttttgc
    48181 gtattgattc gtagacgaat acgattgtct ttttgtagat cttcttcaaa agttgattct
    48241 tcactaactt gaatttttga ggcaaaacct gtctcaatga aatactccgt atttagtcca
    48301 agatagacgc tatcgctaat agttccttcg atatctccag attcatcttt gataaactct
    48361 tcgggacgaa tgcttacatg aatagcttgc tcctcaacct gatcaagagc tagcattcga
    48421 agggcatagc catctgaaaa agacgatata agcgccgtcg ctccgttttt caagattggc
    48481 agggataata tttgtgcgtc cgataaaggt tgccacaaac tcattagctg gtttatgata
    48541 gagttctttt ggtcggccga tttgttggat caccccatct ttcataacag caatttggtc
    48601 tgaaatagcc atggcttctt cttggtcgtg ggttacataa acagttgtaa ttcccacttc
    48661 gtgttggatt tctcggatgg cttgacgcat atccaagaga agtttggcct ccagattact
    48721 aagtggctcg tccatgagga gaacacttgg attaaccgct aaggcgcatg ccaaggtgac
    48781 acgttgttgt tgtccaccac tgagtttatc gggctttcga tccgcatatt gagcaatttg
    48841 catgagttca agatacttgt tggtctgttg aatcaattct tcttttggaa ccttcttttg
    48901 cataagacca aaagcaacgt tgtctcgaac agtcaaatgt gggaaaatag cgtagttttg
    48961 gaaaaccatc ccgatattgc gtttgctggg ttccatatta ttgatttttg tatcatcgaa
    49021 gtaaaattct ccatctttga tactgttgaa acctgcaatc atacgaagaa gggtcgtttt
    49081 cccacatcct gaagctccaa gaagggtaaa gagacttcct tttggaattg taatgttcaa
    49141 attctcaata acagggacat cgtggtagat ttttttggcg ttaataattt cgatctcact
    49201 catagtgaac ctcttttact gtttagattg gatatctgta aagacttcgt tgtatttctt
    49261 aacgatatct gatttattct tgatgacata atcataatct tcagtgagtg ttttgatttt
    49321 gtcaattggt ttcatgtttt cgcttgtttt agcattttta cgaacaggac ggttagtagt
    49381 ggttgtacca agtgtatctt gtacttcttg agagataata aaatcgataa atttcttggc
    49441 attttccata tttttagatt ttttaacgat agcagcacta gcaggtagga agacggttcc
    49501 ttcttttgga tagactacct taatgttagc tccgtcattt aagagtttaa ctgctggatc
    49561 ttcataagag agaccaacag tcatttctcc atcagcgact gctttataga caccagatga
    49621 acttaaaccg attttatagt atattgaaac tagaatagta cacatctact tctaaaatat
    49681 tgttagaaat cgatttgact gtcctgatta atttgtccta ttcttatttc attttactat
    49741 accatcaata agtgtgaaaa gatcttttac ataagaccaa gccttatcat ctttgtaacc
    49801 accttgagct tgtagcatat ttgttaattg agcaaaggcg ctagaagagt ttgctgggtc
    49861 agcagttgcg attttttctt ttagttcagg tttgagaaga tcgttatatc cttcgatgtt
    49921 catgccttta gttaaatcag ggtggacgat taaaacacta ccatctagtg tataaggagt
    49981 agagaagcca gttgtgtttt gatattcttt gataacatta tcattttctt ttgaaatata
    50041 gttttcaaag agttctccgt gggtagcata ttgtgtataa gaaccaccaa aggtaacatc
    50101 agctacagga acttcttttt ctgactctag ttttttgaaa agttctccag taccagcttg
    50161 aatcagttct attttgatac catatttttc ttcaaaggca ggaatagttg ctccaattaa
    50221 gccttctgag tttggtgaat aaacgactag cgaaccaccg tctcctttat cagatgaact
    50281 gtcatcggca gattcattag aagaacaagc agcataatac atccatttct ttttcatgat
    50341 ggatacctcc gttgtgttat ttaagtttat tttaaaacaa tgtaagcgtt tttaaaacct
    50401 acaattctat tctatagtgt attgaatcta taacagtaca ctttgact
//
LOCUS       DAVLTT010000008        49781 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLTT010000008 DAVLTT010000000
VERSION     DAVLTT010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49781
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.008"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(87..1448)
                     /gene="dnaA"
                     /locus_tag="VYN15_000520"
     CDS             complement(87..1448)
                     /gene="dnaA"
                     /locus_tag="VYN15_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV1451888.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(1661..2419)
                     /locus_tag="VYN15_000521"
     CDS             complement(1661..2419)
                     /locus_tag="VYN15_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV1451889.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(2477..3658)
                     /locus_tag="VYN15_000522"
     CDS             complement(2477..3658)
                     /locus_tag="VYN15_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEV1451890.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            3841..4320
                     /gene="rlmH"
                     /locus_tag="VYN15_000523"
     CDS             3841..4320
                     /gene="rlmH"
                     /locus_tag="VYN15_000523"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV1451891.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            4364..4437
                     /locus_tag="VYN15_000524"
     tRNA            4364..4437
                     /locus_tag="VYN15_000524"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4398..4400,aa:Arg,seq:tct)
     gene            4602..4727
                     /gene="comC"
                     /locus_tag="VYN15_000525"
     CDS             4602..4727
                     /gene="comC"
                     /locus_tag="VYN15_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV1451892.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRISRIILDFLFLRKK"
     gene            4748..6073
                     /locus_tag="VYN15_000526"
     CDS             4748..6073
                     /locus_tag="VYN15_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1451893.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYVFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVIFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            6070..6822
                     /locus_tag="VYN15_000527"
     CDS             6070..6822
                     /locus_tag="VYN15_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1451894.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            6874..6945
                     /locus_tag="VYN15_000528"
     tRNA            6874..6945
                     /locus_tag="VYN15_000528"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6907..6909,aa:Glu,seq:ttc)
     gene            6951..7024
                     /locus_tag="VYN15_000529"
     tRNA            6951..7024
                     /locus_tag="VYN15_000529"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6985..6987,aa:Asn,seq:gtt)
     gene            complement(7065..7607)
                     /locus_tag="VYN15_000530"
     CDS             complement(7065..7607)
                     /locus_tag="VYN15_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV1451895.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            7786..8553
                     /locus_tag="VYN15_000531"
     CDS             7786..8553
                     /locus_tag="VYN15_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV1451896.1"
                     /translation="MIGISLIPALYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            8638..8913
                     /locus_tag="VYN15_000532"
     CDS             8638..8913
                     /locus_tag="VYN15_000532"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451897.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFLQQYQQI"
     gene            9003..9317
                     /locus_tag="VYN15_000533"
     CDS             9003..9317
                     /locus_tag="VYN15_000533"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV1451898.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(9418..11970)
                     /locus_tag="VYN15_000534"
     CDS             complement(9418..11970)
                     /locus_tag="VYN15_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV1451899.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSYYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIENQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(12032..13654)
                     /locus_tag="VYN15_000535"
     CDS             complement(12032..13654)
                     /locus_tag="VYN15_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1451900.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            13860..14885
                     /gene="trpS"
                     /locus_tag="VYN15_000536"
     CDS             13860..14885
                     /gene="trpS"
                     /locus_tag="VYN15_000536"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV1451901.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEENKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSGVKGA
                     MGLHYFN"
     gene            15037..16515
                     /gene="guaB"
                     /locus_tag="VYN15_000537"
     CDS             15037..16515
                     /gene="guaB"
                     /locus_tag="VYN15_000537"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV1451902.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(16566..17663)
                     /gene="recF"
                     /locus_tag="VYN15_000538"
     CDS             complement(16566..17663)
                     /gene="recF"
                     /locus_tag="VYN15_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV1451903.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNRN"
     gene            complement(17666..18034)
                     /locus_tag="VYN15_000539"
     CDS             complement(17666..18034)
                     /locus_tag="VYN15_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV1451904.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SCRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            18193..19443
                     /locus_tag="VYN15_000540"
     CDS             18193..19443
                     /locus_tag="VYN15_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1451905.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKGWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            19440..20723
                     /locus_tag="VYN15_000541"
     CDS             19440..20723
                     /locus_tag="VYN15_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1451906.1"
                     /translation="MTKVVFEKKYYPAVKEMIYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLYLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            20765..21586
                     /locus_tag="VYN15_000542"
     CDS             20765..21586
                     /locus_tag="VYN15_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1451907.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            21597..22142
                     /gene="pgsA"
                     /locus_tag="VYN15_000543"
     CDS             21597..22142
                     /gene="pgsA"
                     /locus_tag="VYN15_000543"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV1451908.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            22139..22966
                     /locus_tag="VYN15_000544"
     CDS             22139..22966
                     /locus_tag="VYN15_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1451909.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVIFITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            22951..23790
                     /locus_tag="VYN15_000545"
     CDS             22951..23790
                     /locus_tag="VYN15_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1451910.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRIFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            23783..24577
                     /locus_tag="VYN15_000546"
     CDS             23783..24577
                     /locus_tag="VYN15_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1451911.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            24636..25454
                     /gene="mreC"
                     /locus_tag="VYN15_000547"
     CDS             24636..25454
                     /gene="mreC"
                     /locus_tag="VYN15_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV1451912.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            25454..25948
                     /gene="mreD"
                     /locus_tag="VYN15_000548"
     CDS             25454..25948
                     /gene="mreD"
                     /locus_tag="VYN15_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV1451913.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            26042..27220
                     /locus_tag="VYN15_000549"
     CDS             26042..27220
                     /locus_tag="VYN15_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV1451914.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            27444..28223
                     /gene="rpsB"
                     /locus_tag="VYN15_000550"
     CDS             27444..28223
                     /gene="rpsB"
                     /locus_tag="VYN15_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV1451915.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAALETQADSIEEIVEVVEGDNA"
     gene            28302..29342
                     /locus_tag="VYN15_000551"
     CDS             28302..29342
                     /locus_tag="VYN15_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV1451916.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            29588..29875
                     /gene="tnpB"
                     /locus_tag="VYN15_000552"
     CDS             29588..29875
                     /gene="tnpB"
                     /locus_tag="VYN15_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1451917.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(30066..30353)
                     /locus_tag="VYN15_000553"
                     /pseudo
     CDS             complement(30066..30353)
                     /locus_tag="VYN15_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            30344..30742
                     /locus_tag="VYN15_000554"
     CDS             30344..30742
                     /locus_tag="VYN15_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1451918.1"
                     /translation="MKAPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEGWARM
                     GLPITRKEIVNWHIKASQYYLEPLYNLLRERLLTQSLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(30939..31859)
                     /gene="cysK"
                     /locus_tag="VYN15_000555"
     CDS             complement(30939..31859)
                     /gene="cysK"
                     /locus_tag="VYN15_000555"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV1451919.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(32144..32779)
                     /locus_tag="VYN15_000556"
     CDS             complement(32144..32779)
                     /locus_tag="VYN15_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV1451920.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            32835..34133
                     /locus_tag="VYN15_000557"
     CDS             32835..34133
                     /locus_tag="VYN15_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1451921.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQVVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLDLYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            34130..34792
                     /locus_tag="VYN15_000558"
     CDS             34130..34792
                     /locus_tag="VYN15_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV1451922.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            34872..35420
                     /gene="raiA"
                     /locus_tag="VYN15_000559"
     CDS             34872..35420
                     /gene="raiA"
                     /locus_tag="VYN15_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV1451923.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            35556..37529
                     /locus_tag="VYN15_000560"
     CDS             35556..37529
                     /locus_tag="VYN15_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV1451924.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDTFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDHVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            37526..37978
                     /gene="rplI"
                     /locus_tag="VYN15_000561"
     CDS             37526..37978
                     /gene="rplI"
                     /locus_tag="VYN15_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV1451925.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            38022..39374
                     /gene="dnaB"
                     /locus_tag="VYN15_000562"
     CDS             38022..39374
                     /gene="dnaB"
                     /locus_tag="VYN15_000562"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV1451926.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            39376..39642
                     /locus_tag="VYN15_000563"
     CDS             39376..39642
                     /locus_tag="VYN15_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451927.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            39731..41077
                     /gene="cbpD"
                     /locus_tag="VYN15_000564"
     CDS             39731..41077
                     /gene="cbpD"
                     /locus_tag="VYN15_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV1451928.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      41160..41262
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            41333..41623
                     /locus_tag="VYN15_000565"
     CDS             41333..41623
                     /locus_tag="VYN15_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV1451929.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVPMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            41586..42344
                     /locus_tag="VYN15_000566"
     CDS             41586..42344
                     /locus_tag="VYN15_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1451930.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            42382..43389
                     /locus_tag="VYN15_000567"
     CDS             42382..43389
                     /locus_tag="VYN15_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1451931.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            43389..44117
                     /locus_tag="VYN15_000568"
     CDS             43389..44117
                     /locus_tag="VYN15_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1451932.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            44236..44694
                     /locus_tag="VYN15_000569"
     CDS             44236..44694
                     /locus_tag="VYN15_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV1451933.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            44696..47128
                     /locus_tag="VYN15_000570"
     CDS             44696..47128
                     /locus_tag="VYN15_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1451934.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            47770..48423
                     /gene="rr06"
                     /locus_tag="VYN15_000571"
     CDS             47770..48423
                     /gene="rr06"
                     /locus_tag="VYN15_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV1451935.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            48420..49760
                     /gene="hk06"
                     /locus_tag="VYN15_000572"
     CDS             48420..49760
                     /gene="hk06"
                     /locus_tag="VYN15_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV1451936.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
BASE COUNT        15604 a         8111 c        10435 g        15631 t
ORIGIN      
        1 cagcctttaa acaagtcata tcaagttttt tagcttgttt aaaaaatgtg gataaaaaag
       61 ataaaaaact aaaagttatc cacaaattat ttgattttct ttttgattga ttcaatttct
      121 aaacgtaaat tatcgtcttg atcaatcaaa gattttattt tggcatgggc atgaatgact
      181 gtggtatgat cttttccccc aaattccttc ccaatttttg gaagactatt atctgttagt
      241 tctctagata aatacatggc tacttgacgg gccaaaacaa tattttgaag gcgtctactt
      301 cccttcattt ctttgatact aacaccataa aagttaccaa cttcagtttg gattttatca
      361 attgggatga cgagcatttg gctaacatct tgtttgcggg ctctaatggc ttctgcagca
      421 atatcaatag tgatatcctt gatttttttt actctggcaa ttaaagtgat gtcgttgatg
      481 gctccctcaa gatctcgaac atttgaatca aattgcccag ctaggtattc tagagtatca
      541 ctttggaaat tgtagcctaa atgttccgtt ttactttgta aaatggcaat acgtgtttca
      601 aagtcagggg gtgtgatagt ttgtgtcaat ccccaactaa aacgcgtgac aagcctctcc
      661 tcgagccctt ctagatgttt tggactacga tcactcgtta ggacaatctg tttttgcttg
      721 tcatgaaggg cgttaaaggt attgaaaaat tcttcctgag ttgcgacttt ttttccgctg
      781 agtgactgga tatcatcgat taacaaaaga tcaagactac gataggtctt tttaaacttt
      841 tccatttccc caagtcttag gtgatcaaga aagtcattaa taaagctttc ggcagggata
      901 tatttaacac gcgcattagg aatatttttt agaatttcat ttccaatagc gtttaataag
      961 tgagtcttac caaggcctgg tcctccatag ataaaaagag ggttataggt cagagccaaa
     1021 tcttcagaga cagctaaagc ggctgataca gcccaaacat ttccatcccc ttgaataaag
     1081 ttatcaaagg tatacttttc ttttaatccc gtatctgaat aaggaataga tactaacttt
     1141 ggactatagt cataaagagt taaatttgta gcttcttcaa cttgtgagct agtcgtatct
     1201 tgaggtttgg tgaaaatata gtggggagtt atttcagcgt cataaatttc aaaaccagct
     1261 actacaataa tatcttttag ttgtttttcc cagaccattt ccatttcaga gcgaggtaga
     1321 aatatagtgg caacattttc ctctaccttg ataagttcag cttgaatagc atagaaatca
     1381 tacatggatc gagtcagtct ttcttgtgca aattctaata tacgattcca aaattgtttt
     1441 tctttcaatc ctttctcctc ctttactatt taaaagttta atactagaga tattttacca
     1501 tagatagcaa gaattttcca caagctgtga aaaataatcc acaatgttac taaactttat
     1561 ccacaggttg gggataaaag aagaaattat tgatttatta agctttttat cgaaaaacat
     1621 agtggataac cttgtgagat aaaaaaataa aagaacagcc ttatttcagg ctgttgataa
     1681 ttctactata ttcttcttga tttgaaaaag aaataatgat ttttccactg tcttttttag
     1741 atagtttaat ttctacatct aatccgagta gttttcttaa ctgtttttct tcattttgta
     1801 tgaaatgatt agttttttgc tgtttctttt gttttttctc tgtcagaaga gcttctaact
     1861 tccttacaga aatatcttct tctataatcc gttgaaagaa atagtcttgt tgttccttat
     1921 ttaacccaac tagggaacgc gcatgggctt gtgatagttt gccattttct acttctgaga
     1981 gaatctgttc tggcaaggaa agtaaacgaa tggagttgct gatatatgga cgagacttgc
     2041 ccatcttatc tgcaatttca gcatgggtga atcctttctc tacgagagat tcataggcgc
     2101 gtgcttcttc tattgggttt aaattttctc tctgtaaatt ttcaataatg gactggacca
     2161 tcatctcttg gtctgaaatc tgtttaacaa cagctgggat agaccgtaga ccagctaaaa
     2221 gtgaagcccg atagcgtctc tctcctgcaa ggatttcata accaataaca ggagattgac
     2281 gaacaataat cggttgaatg accccatttt ctttgataga ctgtgctagt tcatctagtt
     2341 tttctctatc aaattctttt cggggttgat agggattttt ttgtatatct gtgatagaaa
     2401 tcatttcaaa tttttccatg attctacact aacacatctt ttctcttatg taaagctttc
     2461 tttacataga tgtcaattaa gattctaaat cacctgaact cttgttaagt ttgatagagg
     2521 tagtttcttc tttcccgtta cgatagtagg ttatcttaat ggtgtctccg atagaatggt
     2581 tgtaaagagc actttgtaag tctgttgatg aagcaatctc tttgtcatct acttttgtaa
     2641 ttacatcgta tttttcaagg tgaccattgg caggcatatt actttgtacc gaacgaacaa
     2701 ttacaccaga tgtaacatta cttggaatat tgagtcttct gatgtcgctt gtactcacat
     2761 tagataaatt aaccatctgg attcccaaag ctggacgcgt cacttttccg tttttttcta
     2821 actgttcaat aatattgata gcatcatttg caggaattgc gaaaccaaga ccttctacag
     2881 atgttcctcc atttgtagca attttacttg aggtaattcc gataacctgc ccttgaatat
     2941 tgatcagtgg gccgccagag ttacctgggt taatagcagt atcagtttgg atggcttttg
     3001 tagaaatagc ttgtccatct tccgatttta aggatacatt tctattgaga ctggatacga
     3061 taccttgagt gacagtattt gcatattcag aacctaacgg gctaccgatg gcaatagcag
     3121 tttctcctac agttaactta ctagaatcac caaactcagc tactgttgtc actttttctg
     3181 aagagatttt gacgacagca atatcagaga aagtgtcagc tccgacaatt tctccaggta
     3241 ctttagtccc atctgacaat cgaatatcta ctttgctggc gccatttata acgtgattgt
     3301 tggtgacgat gtaagcttct ttatcattct ttttataaat aactccagat ccttcactag
     3361 agattcgctg agaatctgtg tcagtatcat cattgccaaa tacgctattt tgtctgtttg
     3421 ccgaataagt aataacagaa acaacagcat cttttacttt gttaacagcc tgtgttgttg
     3481 aattttcgtt cttataggca gtttgtgtaa tagtactatt gttgttagag ttgtttacac
     3541 tacttttttg agttagttga gttattgaaa aactacccaa ggctccacta aaaaagctaa
     3601 tgacgataac gactaataat tgaaaccatt ttttgtaaaa tgtttttaga tgtttcatat
     3661 ttgcctccat atgtttgaat tactgaaagt ataaactgac tagcttaatt ataacttaaa
     3721 cacaaaagtt ttacacaaac tgtggataac tcttttgaaa ttgtgatttt cttaattgaa
     3781 atctattttt tattttgtga ataagatgtg aaaaaataga gaatatgtta gaatagagtc
     3841 atgaaaatta aagttgtaac agttgggaaa ctgaaagaaa agtatttaaa agatggtatc
     3901 gcagagtatt caaaacgaat ttctagattt gctaagtttg aaatgattga gttatcagat
     3961 gaaaaaacac cagataaggc cagtgaatca gaaaatcaaa agattttaga aatagaaggt
     4021 cagagaattt tatcaaaaat tgctgaccgt gatttcgtta ttgtgttagc cattgaaggg
     4081 aaaactttct tctcagaaga atttagtaag cagttagaag aaacttctat aaaaggattt
     4141 tctactctta cttttattat tgggggaagt ttaggattat catcatctgt aaaaaataga
     4201 gccaatcttt ctgtcagttt tggtcgccta accttacccc atcagttaat gagactagtt
     4261 cttgttgaac aaatctatcg cgcttttacg attcagcagg gattccccta ccataaatag
     4321 aaaattgact tttaattgaa tttttggtag aataattgta ttaggtctca tagctcagct
     4381 ggatagagca ttcgccttct aagcgaacgg tcgcaggttc gaatcctgct gggatcaata
     4441 taatagcaaa gctgggaatt ttcccggctt ttttcttaaa aaagtacact ttgggagaaa
     4501 aaaatgacag ttgagagaat tttatctaaa acgaaattcc attttgtata atggtttttg
     4561 taagttagct tacaagaaaa aacattttag gagattttat tatgaaaaac acagttaaat
     4621 tggaacagtt tgtagctttg aaggaaaaag acttacaaaa gattaaaggt ggggagatga
     4681 ggatttcaag aatcatcctt gattttcttt tcctacgaaa aaagtaatga aataaggaga
     4741 aagagtaatg gatttacttg gatttgggac agttattgtt cattttttaa ttattagtca
     4801 cagttaccgt ttaatttgta aaggtcgaat aaatagaaaa gaattatacg tttttggtgc
     4861 ttatacatta ctaactgaaa tagtacttga attttccttt tatcttctat atttagataa
     4921 aatagggatt gaaagatttt tatttccttt gggcttatat tcctattttc gatggatgaa
     4981 acagtatgag agggatagag gactattcct aagtttacta ctatctcttt tatatgagag
     5041 cactcataac tttctgtccg taattttctc ctctataaca ggagataatt ttgttttaca
     5101 atatcatttc ccattctttt tcgttgtgac ggtgttaacc tattttgtta cattaaaaat
     5161 catttactat ttccatttgg aactagccta ttttgacaag gactaccttt atcctttctt
     5221 gaaaaaagta ttttttgctt tactattgct acatattgta tctttcgttt cagatatggt
     5281 aagtacgatt aaacatttga atagttttgg aagtattttg tcatctattg tctttatctc
     5341 tctccttttg accttctttg caatgaattc tcataaagtt caaatggaga aagagattgc
     5401 tttgaagcag aagaaatttg aacagaaaca tttacagaat tacacagatg aaattgttgg
     5461 tctgtataat gaaatccgtg gttttcgaca tgattatgct ggaatgcttg tcagcatgca
     5521 gatggcaatt gacagtggta atttacagga aattgacaga atttacaatg aagttttagt
     5581 caaagcaaat cataaattgc gttcagataa gtacacttac tttgatttga acaacataga
     5641 agactcagct ttacgaagtt tggttgctca gtcaattgtc tatgctcgaa ataatggtgt
     5701 agagtttaca ctggaagtaa aagatacgat taccaagctt ccaattgaac tattggattt
     5761 ggttcgtatc atgagcgttt tattgaataa tgctgtcgaa ggatcggctg atagctataa
     5821 aaagcagatg gaagtagcag ttattaagat ggaaactgaa acagttattg tgattcagaa
     5881 ttcatgtaaa atgacgatga ctccttcagg agatctattt gccttaggat tctccactaa
     5941 gggaagaaat cgcggagtcg gattaaataa tgtgaaagaa ctactagata agtacaacaa
     6001 tattatttta gaaacagaga tggaaggcag tacatttaga caaatcatta gatttaagag
     6061 ggaatttgaa tgaaagtttt aattttagaa gatgttattg aacatcaagt gagactagag
     6121 agaatattgg atgaaatttc gaaagaatcg aatattccaa tatcatacaa gacaacggga
     6181 aaagtccgtg aatttgaaga atacattgaa aatgatgaag taaatcagct ttatttccta
     6241 gatatcgata ttcatggaat tgagaaaaag ggatttgaag tggctcagct cattcgtcat
     6301 tacaatcctt acgctattat cgtctttatc actagtcgat cagagtttgc gactctaacc
     6361 tataaatacc aggtatcagc cctagatttt gttgataagg atatcaatga tgagatgttt
     6421 aagaagagaa ttgagcaaaa tatcttctac acgaagagta tgttacttga aaatgaagat
     6481 gttgtagatt atttcgacta caattacaag ggaaatgatt taaaaattcc ttaccatgat
     6541 attttgtata ttgaaacaac aggggtatct cataaattgc gcattattgg taagaatttt
     6601 gcaaaagagt tttatggtac catgacagat attcaggaaa aggacaaaca tactcagcga
     6661 ttttattctc ctcacaagtc atttttggta aatataggca atatcagaga aattgatcga
     6721 aaaaacttag aaattgtttt ctatgaagac catcgttgtc ctatttcaag attaaaaatt
     6781 agaaaattaa aagatatttt agagaaaaaa tctcaaaagt gattgacaat tagcaagaaa
     6841 ttgatataat ggttatatct gctacagata gaaggtccgt tggtcaaggg gttaagacac
     6901 cgccttttca cggcggtaac acgggttcga atcccgtacg gactatttta tccgccatag
     6961 ctcagttggt agtagcgcat gactgttaat catgatgtcg taggttcgag tcctactggc
     7021 ggagtataga taaaagggaa cacagctgtg ttcctctttt tgtatcaatt tgtatcacca
     7081 agcattttca taaggaagtc tgttatttct tgagaacttt ctttttttcc atgtgcaatc
     7141 caagtttggc agacaccaaa aagtgcatga gttagataga tgctactata ttctaattca
     7201 gtggtattta gattcagttg cataaatcgc ttttgtaaat ctgtactaag catgatatga
     7261 agtttatttc gtaagaaatt ttggatttct ttagtcccat tttcagaaag aagggcagcc
     7321 agaagtggtt ctgactctag atattcaaaa acttctaaaa tagcgtctct tttgtgatga
     7381 gcatgttttt gaaaaatata ttcaaatgta tggaatagct tgctttgata gtgctcaatc
     7441 atatcatact tatccttata gtgagtatag aagctggaac gactaattcc ggctttttct
     7501 actaatttga cagtagaaat tttatcaaat ggctgttcca tcagtaattg taccatagca
     7561 ttttcaatag ttcgctttgt ttttaagcgt ttgttacttt cttgcatatt tcctccttgt
     7621 aaacaaatta gactatatgt ctaaaaatat attttttatc ttgtaattta gattttttaa
     7681 tgtataatct attatatcaa aattttagac aatgtgttta aaaaaggaga aattatgttt
     7741 aaagaatgga aagcaattta aaaaaaacca acctttatta ttgtcatgat cgggatttct
     7801 cttattccag ctctgtacaa tatcatattt ttgtcatcaa tgtgggatcc atatgggcaa
     7861 ttgtctgact tacctgtggc agttgtaaat aatgataaag aggcttccta taatggtaat
     7921 actatggcaa taggaaaaga catggtgtcc aatttaaaag aaaataaaac cttggatttt
     7981 cattttgtag atgaagagga aggaaagaag ggattggaag atggcgatta ctatatggta
     8041 gtgactttac caagtgattt atctgaaaaa acaactacat tatccaatat tcaatcgaca
     8101 gcagcttatc aatcattgac aagtgagcaa caaactgaga taagtgattc tgtatctcaa
     8161 aattcaactg atagtattca atcggctcag tcaattgtag ctttagtaca agatttacag
     8221 ggaagtttag aaaacttaca aaatcaatct tctaatcttt cgactttaaa aaatcaatct
     8281 aatcaagtat cacctattac ttctacttct ttgataggat tgtcaagtgg attaacagag
     8341 atacaaggag atgttactag caaattagtt cctgccagtc agtcgattgc atcaggtgta
     8401 aacgcatata ctacaggtgt tgataaagtt tctcagggcg caagtcaact aagtgaaaaa
     8461 aatgccacct tgacaggtag tttggataaa ctagtttcag gctcaaacac cttgacacaa
     8521 aaatcttcta gattgacagc aggagttggt taattacaat caggatctgg gcaattagca
     8581 gacaaatcca gttagttact ttcaggtgct tctccattag agaatagagc taataaattg
     8641 gcagatggat ctgggaaact agcagaaggt ggaacaaagt taacttctgg attggaagat
     8701 ttacagacag gacttgcttc tttaggacaa ggactaggta atgctagtga tcaactcaaa
     8761 tcagtatcaa cagaatctaa aaatgcagag attttgtcaa atccactcaa tctttcaaaa
     8821 acagacaatg atcaagttcc tgtaaatgga atcgcaatag ctccttatat gatatcagtt
     8881 gctctttttt tgcagcaata tcaacaaata tgatatttgc gaaattgcct tcaggacgtc
     8941 atccagagag ccgttgggct tggttgaaat cttgagctga aataaatggt attatagctg
     9001 ttttggcagg aattttggta tatggaggag ttcagcttat tggtttaact gctaatcatg
     9061 agatgagaat atttattctc atcatcctaa caagtttagt attcatgtct atggtgacca
     9121 ctttagcaac gtggaatagc cgtataggag cttttttctc acttattttg cttttactac
     9181 agttagcatc aagtgcaggt acttatccac ttgctttgac aaatgatttc tttagatcta
     9241 ttaatccctg gttaccaatg agctattcag tttcgggatt acgacaaaca atctctatca
     9301 acaagtcatt ttcctagctg tcatactagt tctatttact agtttaggta tgctagccta
     9361 tcaacataag aaaatggaag aagattaaaa aaatcgaccg attaactggt cgatttttta
     9421 tgccttagat gactttcgtc tgtgattata gattccaaat agtaagagag aagtaaagga
     9481 acagattgct ccagtaataa aaccattggg aatgaaggaa agtgtaatag ttcctttccc
     9541 cttgggaatg tcaactttca taaatccagt ttgagcttgt ttaatttcta ttttcttacc
     9601 atcttggtag gcagaccaac ctttgtcata aggaatggtg aagaaaatag atgtatcttg
     9661 ttggacatca tatgtagcaa aaaccttgtt tttagaagtt gatactgtga caggttgttc
     9721 tttaattttt tgaattgcct cggtgaaagt tttggtatct aaacgataga aggtaggaga
     9781 ttcaaatgat acttgtgaat ttccagggaa actaacattg atattgaaag tttttttctc
     9841 tttagtatat cctagattaa agaaggagaa gacattatca gttgtaaaag tctttttttc
     9901 accatttaca aggatgtcaa ccttcttttg tttatcgtta gaaaagtgaa ggtttatgaa
     9961 agagagataa acttggctgt tttctggaac ttcaatttga tactggattg ctgcatcttc
    10021 atttgaagaa cttgttacac taatcaaatc attagtattt tctatttttt ctgttttttc
    10081 ataaggtatt ggagaaaaat aatcaaaatt gacgttagca agttgattta aaaatgaggc
    10141 ctgattatcc aaggtatgtt cattgaactt gacatcattg taaacagatt gactagcaac
    10201 tgcaatcgga agagagtatt gattttcata tagggtaaga ttatcttttt gatagatatc
    10261 tttaaaacca tacttatcaa taggactgtc tgagatattg tactggatac caaataaact
    10321 atcagccaaa atactattat ttgcatatcg gagattgaga ttagtcccag aggatttaaa
    10381 accaagttta tctaaagtag agcttgatga acgatttcga acagatgaaa attgagagat
    10441 tccattgtag ttgaatttca tactgtcatt tcctgtctga gtttgtagtt tttcagtacg
    10501 agtaaattga ttttcaatat atgttgagaa agattccata gctgggatat ctcgactata
    10561 agcacttcga gaagcaaatc cccattcctt agcaattccg tccatttgag atgaagcatt
    10621 taaactcatt tcaaccagta taaataaaga gattagaatg gcaaatagat tcacagatat
    10681 aaactttttg ataactgcaa ggagtaaaag agaatagaca accaaaaatt caagagtaag
    10741 cagaatattc aaatctgtta aaaaagaata atacgatttt agatagatgg tagctaaaaa
    10801 tcctgttact acaagaaaaa gcgaaactaa aaaattccag actttaagtt ctttcagacg
    10861 ctttaagact tctgctgctg tgtaaattaa caaggtagag aaaatccaag catagcgatg
    10921 taaaaacatg tttggagtat gcatgccttg ccaaaataag tcaagagctt ctatgtaaaa
    10981 gcttgcaatt agaaatgcaa agaatattac atatatgagt ttcacgtgaa acttaataga
    11041 tttcagcgta aaaaataaaa tggtcaaaat aaagggaagt agtccaacaa aaatcattgg
    11101 gatggcccca tactttgttg tgtcaaagga accaatgaat tgcttagcaa agagatcaag
    11161 ataccagcta ctttcagttt gaaactttgt aacttcagtc aatttttccc catgtgtctg
    11221 taaatcaaat agagtgggaa gagtcataat caaactagcc ataccagcta aaaaggagat
    11281 aactatgaaa tcaagaacag atgattttcg agtcttaaag tcccacgaaa tttgacagag
    11341 ataccagaaa ataagaaaca atactgtcat atatccaaaa taataatttt gaataaataa
    11401 gattgacaga cttgtaaagt acaataggag tttcttttca gttatcagta gatgtaaacc
    11461 agttataatt aaaggaatca agataaaaac atctagccag gtttttatct ctaattgact
    11521 gacagtgaaa ctcatcagag cataggaagt agataaggct agttttaaag tctgagggat
    11581 agattgaaac aatttattca aactaaaaaa ggttgacaga ccaatcaatc caaattttaa
    11641 gagagtggtc agatagacag catctggcat attcgttaga tcaaaaaagt aaaccagagg
    11701 cgcgagaaaa ctacccaagt aataactaga tagggcatag aagtttagcc ctagaccact
    11761 tgtaaaggtg taaaacagac tactatttcc atgtaggata tttcgtaagg ctacatcaaa
    11821 aataacgtat tgatgaaagc catctcctaa tagaggagag ttgtcgctat tccagtagat
    11881 accttgagat agatatactc cagacataat cactacagga atgatgaaag aaataaaata
    11941 ggttcgatat gtttttaaaa atgatttcat gttacctcgt agaatgatag aaaactcagt
    12001 tggttaaccc aactgagttt tgaagtttta tttagtcttt ccaaagttct ttaacttttg
    12061 cttgtacttc tgcattttct aggaattcat cgtaggtttc atcgatacgg tcaatgacgc
    12121 catttttaga taagacaatg atatgattag ccaaagtttg aataaattcg tggtcatggc
    12181 tggcaaagat gattgattct ttaaagtttt tcaatccatc attcaagctt gagatagatt
    12241 ccaagtccaa gtgatttgtt ggatcatcaa gtacaaggac atttgatttt aagagcatga
    12301 gttttgaaag catgacacga actttttctc cccctgacaa gacatttaca ggtttgttaa
    12361 cttcatctcc agagaagagc atacggccga ggaagccacg taggaaagta ttgtcatctt
    12421 cttctttact tgcgaattga cgcaaccagt caagaattga ttctcctcct gcaaaatcag
    12481 ctgagttatc ttttggtagg taagattgac tagttgtaac tccccacttg acagttcctt
    12541 catagtcaat atctcccatg attgcacgaa ttaatgcagt cgtttgaata tcattttgtc
    12601 caataagtgc tgtcttatca tctggacgca agatgaaact aatattatcc aagatagttt
    12661 caccatcaat ctttacagtt agattttcta ctgtcaagag atcattacca atctcacgtt
    12721 ccgctttaaa gttgataaat ggatatttac gactagatgg tacaatctct tctagctcaa
    12781 tcttatcgag cattttctta cgtgatgttg cctgccttga cttagaagca ttggcagaga
    12841 aacgagcaac gaattcttgc aattgtttaa ttttttcttc tgctttagca ttacggtctg
    12901 ctagcaattt agcagcaagc tcagaagatt ccttccagaa gtcgtagttt ccgacataga
    12961 gtttgatttt tccaaagtca aggtcggcca tgtgagtaca aactttgttt aagaagtgac
    13021 ggtcgtggga tactacgata actgtgttat caaagtcaat caagaagtct tctaaccaag
    13081 taatcgattg gatatccaaa ccgttagtag gctcgtccaa gagaagaaca tctggtttac
    13141 caaaaagtgc tttggcgagg agaaccttta ctttttcacc gttggccaat tcgctcatgt
    13201 tttggtagtg taattcttct ggaatgttta ggttttgaag tagttgagag gcttcactct
    13261 ctgcttccca acctccaagt tcggcaaact ctccttcgag ttcggcagca cgaaccccgt
    13321 cctcgtctga gaaatcttcc ttcatgtaga tagcatcttt ctctttcatg atgctataaa
    13381 gtttttcatt tcccatgata acgacatcaa tggcacgttc atcttcgtag tcaaagtgat
    13441 tttgacgaag aacagagaga cgttcatctg gaccaagaga gatgtgacca gtagtaggtt
    13501 cgatatctcc agctaaaatt tttaaaaagg ttgattttcc ggcaccatta gcaccgatta
    13561 atccgtaagt atttccttct gtaaatttga tattgacatc atcaaaaagt ttgcgatcac
    13621 taaaacgtag tgaaacatca gatactgtaa gcaatgtttt tctcctatat gtgtaatata
    13681 tttattctac tagaaaatac agaaatattc aaatttttat ttgtcaattt tgtgtaaatt
    13741 atatttacag tatcctttac acaaatctgt aaaaagcaag gctgatttat tttgataaat
    13801 tacggttatt tcattaaaaa aatgctataa ttgaaaggac tatatcgaag gagaacaaaa
    13861 tgactaaacc cattatttta acaggagacc gtccaacagg aaaattgcat attggacatt
    13921 atgttggaag tctcaaaaat cgagtattat tacaggaaga gaataagtat gatatgtttg
    13981 tgttcttggc tgaccaacaa gccttgacag atcatgccaa agatcctcaa accattgtag
    14041 agtctatcgg aaatgtggct ttggattatc ttgcagttgg attggatcca aataagtcaa
    14101 ctatttttat tcaaagccag attccagagt tggctgagtt gtctatgtat tatatgaatc
    14161 tagtttcgtt agcacgtttg gagcgaaatc caacagtcaa gacagagatt tctcagaaag
    14221 gatttggaga aagcattccg acaggattct tggtctatcc aatcgctcaa gcagctgata
    14281 tcacagcttt caaggctaat tatgttcctg ttggaacaga tcagaaacca atgattgagc
    14341 aaactcgtga aattgttcgt tcttttaaca atgcatataa ctgtgatgtc ttggtagagc
    14401 cggaaggtat ttatccagaa aatgagagag cagggcgttt gcctggttta gatggaaatg
    14461 ctaaaatgtc taaatcacta aataatggta tttatttagc tgatgatgcg gatactttgc
    14521 gtaaaaaagt aatgagtatg tatacagatc cagatcatat ccgcgttgag gatccaggta
    14581 agattgaggg aaatatggtt ttccattatc tagatgtttt tggtcgtcca gaagatgctc
    14641 aagaaattgc tgatatgaaa gaacgttatc aacgaggtgg tcttggtgat gtgaagacca
    14701 agcgttatct acttgaaata ttagaacgtg aactgggtcc tattcgtgag cgccgtattg
    14761 aatttgctaa ggacatggga gaagtttata atatgattca aaaaggtagt gaaagagcgc
    14821 gtgaagttgc gggtcaaacc ctatctgggg taaaaggggc aatgggactt cattacttta
    14881 actaagttta ttttacaaga aactatcttt tctatctcga agaaaagata gttttttatt
    14941 tacccctgta acatttgaca aatttttata gaatggtatg atagatacaa tataaaaaga
    15001 gtcaagctca aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga cactaaattt
    15061 ttgaaaaaag gttttacctt tgatgatgta ttgcttattc cagctgaaag tcatgtgttg
    15121 cctaacgatg cagatttaac aactaaattg gcagataatt tgactttaaa tatcccaatt
    15181 attaccgctg ccatggacac agttacagag agtcaaatgg ccattgctat tgctcgtgca
    15241 ggcggtctcg gagttatcca taaaaacatg tcaattgctc aacaagcaga cgaggttcgt
    15301 aaggtaaaac gttctgaaaa tggagttatt attgatccgt tcttcttgac gcctgaacat
    15361 acaattgctg aagcagatga gcttatgggt cgttaccgca tcagtggtgt tccagttgtt
    15421 gaaacacttg aaaatcgtaa attggttggt attttgacaa accgagatct tcgttttatt
    15481 tcagattata atcaaccaat ttcaaaccat atgactagtg aaaatcttgt tactgcacct
    15541 gtgggtacgg atcttgcaac ggctgagagt attcttcaag agcatcgtat tgaaaaactt
    15601 ccgttggttg atgaagaagg cagtctttct ggtttgatca ctatcaaaga tattgaaaaa
    15661 gttattgagt ttccaaatgc ggctaaagat gagtttggtc gtcttctagt tgcaggtgca
    15721 gtaggtgtta cttcagatac atttgaacgt gcagaggctc tttttgaggc aggagcggat
    15781 gcgattgtta ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa aattgccgag
    15841 attcgtgctc atttcccaga tcggactttg attgctggaa atattgctac tgctgaaggt
    15901 gcacgtgccc tttatgaagc gggtgtagac gttgttaagg ttggtattgg accaggttct
    15961 atctgtacta ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc tatctacgat
    16021 gctgcagctg ttgcgcgcga atatggtaaa acgattattg ctgacggtgg gatcaagtat
    16081 tctggagata ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct tggatctatg
    16141 tttgctggaa ctgatgaagc tccaggcgaa actgaaatct tccaaggacg taaattcaaa
    16201 acttaccgtg gtatgggatc aattgctgct atgaagaaag gttcaagcga ccgttatttc
    16261 caaggttctg tcaatgaagc aaacaagctc gttccagaag gaattgaagg tcgtgttgct
    16321 tataaaggag cggcagctga tattgttttc caaatgattg gtggtattcg ctctggtatg
    16381 ggttactgtg gtgcagctaa ccttaaagaa ctacacgata atgctcaatt tattgaaatg
    16441 tctggtgctg gtttgaaaga aagccatcct catgatgtgc aaattactaa tgaggcacca
    16501 aattattcta tgtaaaaaac aatgaaaaga actccagtga aaacaggagt tcttttacaa
    16561 tgttgtcaat ttctatttac agcagcttta ccatcctgaa tagtgaagat acttagattt
    16621 tctggcagat tttgaagatg gtctaagctt gttgttgtga taaaggtttg gattgattga
    16681 gaaatcgttt ctaataattt taactgtcta gtgttgtcaa gttcactcat cacatcgtca
    16741 agcagtaata tcggagattc tgtggtaatg ctttccatta attcgatttc tgctaatttt
    16801 atcgagagga cgagactacg atgttgacct tggcttccga aactagcatc catcccattt
    16861 atataaaaag aaatgtcatc tcgatgagga ccgacaccag tattcttttt aaataaatct
    16921 ctggatctac ttttttctaa agcaattttg aaagattcgg ataagttttg tttgtcagtt
    16981 atattgacag aagattgata ggatattgac aactcttcga tctgattaga gagttcaaaa
    17041 tgtttcttac gcccaaatga ttctagtttt tttatgaaat ctaagcggtg attcattaca
    17101 cgacatccat aatcaactag ctgatcatct aacacagaaa ggaatgtttc atctattttt
    17161 tgagctgatt ttaggtaagt gtttctttgc tttaggatgt ggttataatt ggttaagtca
    17221 gataaataga ttggcttaat ttgcccaagt tccatatcaa tgaattttcg tcgaatcgaa
    17281 ggtgctcctt taattagttg taaatcttca ggagcaaata agacaacatt catgtgtcct
    17341 acataatctg aaaggcgtgc ctgttttaag tgattaactt ttgttacacg gcctttttgt
    17401 gttagttcga tttctagggg aatggatcca gtttttttct gaacgagacc tgaaagatga
    17461 agttgttcct catcaaaatg aatgagattt ttatctgttc gagttcgatg actacgcgtt
    17521 aaggctaaaa aatagatagc ctctaacatg tttgtttttc cttgtgcatt acgtcccaaa
    17581 aagacattca atttaggatt aaagtctatt ttcgtttctt tgtaattacg aaaagtcttg
    17641 agagatagat gttgtagcca catgattatc taccagggaa tcgtggagct tgttggcttt
    17701 taggtgatga agcaggtttc gatttgtctt ttttaactcc cttattcatc tttttgacaa
    17761 gtttagcgat ccgttctttt tcaactttat cagcttggta ttcatcttgt tcttcagaag
    17821 taggttgtgt caacaagatg tcaatgttca tgtcagggat gtcaacttta tcgccaatac
    17881 gaagtttttt tccacgacaa ctctctaatt ccctattaaa gtaaacagaa tgttcagaga
    17941 gaaatgattt aatagctcct ccgctatgtg taattccaag ttctttgagt agtgcttgga
    18001 gggtaataaa ttcttcaaat aatttgtatt ccataattca cctcaatctt tggtattata
    18061 ccatattttc ctaaaaatag tgagagagac agctagaaat gtaagcgatt tttatttcaa
    18121 aagtgttaca gggaacaaga aaatttcagg ttttcgtgat ataatagaag tctgtatata
    18181 aggaggtaaa tcatggagtt agtgcatgga atttcaacac attttatcca atcaaaaaag
    18241 tttaaaacaa acaaaattac cgtgcgtttt accgctccat tatcccttga tacgattgca
    18301 ggtcacatgt tgagtgcaag tatgctagag actgctaatc agatgtaccc cacttctcaa
    18361 gatttgagga gacacttggc cagtctatac ggtacagata tgtcaaccaa ttgtttcaga
    18421 agagggcaaa gccacattat agaattgaca tttacctatg ttcgtgatga gtttttaagt
    18481 aggaaaaacg tgctaacctc tcagattttg gaacttgtaa aagaaactct tttttcaccc
    18541 gcagtagttg ataatgggtt tgatccggcc ttatttgaaa ttgagaaaaa acaattgcta
    18601 gcaagtttag cagctgatat ggatgattct ttttattttg cacataaaga attggataaa
    18661 ttgttttttc atgatgaacg tcttcaattg gaatatagtg atttacgaaa tcgtatttta
    18721 gctgaaactc cacaaagttc ttattcttgt ttccaagaat ttttagccaa tgatcgaata
    18781 gatttctttt tcctaggtga ttttaatgag gttgaaattc aaaatgtatt agaatcattt
    18841 ggctttaaag gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta ttctaatatc
    18901 cttcaggaag gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt aggttatcat
    18961 taccgttcta aatatggtga tgaacaacat ttacccatga ttgtaatgaa tggtttactt
    19021 ggtggatttg ctcactctaa gctctttaca aatgtccgtg aaaatgctgg attagcttat
    19081 accatttcaa gtgagcttga tttatttagt ggattcttga ggatgtatgc tggtatcaat
    19141 cgagaaaatc gtaaccaggc tcgtaaaatg atgaataatc aactgcttga tttaaaaaaa
    19201 ggttatttta cagagtttga gttaaatcag accaaggaaa tgattcgttg gtcgttgtta
    19261 ctttctcaag ataatcaatc ttcattgatt gaacgtgctt atcaaaatgc cttatttgga
    19321 aaatcttcag cagactttaa aggttggatt gcaaaactcg agcaagttga caaagatgct
    19381 atttgtagag cagctaataa tgtgaaacta caggcgattt actttatgga aggaatagaa
    19441 tgacaaaggt tgtttttgaa aaaaaatact atccagctgt aaaagaaatg atttatcgaa
    19501 ctcgtttggc caacggattg acagttgctc ttttgcctaa aaaggaattt aaagaggttt
    19561 acgggagtgt cactgtacag tttggttcgg tagatacgtt tgtcacagaa gttgacggag
    19621 atgtaaaaca atatcctgca ggaattgctc attttcttga acataaatta tttgagagag
    19681 aagattctag tgatttgatg tcggctttta cgagtctagg tgcagatagt aatgccttta
    19741 caagctttac aaaaacaaac tatctttttt cagcaacgga ttatttttta gaaaatttat
    19801 atttacttga tgaattggta acatcagcac actttactga agcttccatt ctgacagagc
    19861 aggatattat tcagcaagaa cgagaaatgt accaagatga tccagattcg tgtttattct
    19921 tttcaacttt agcgaatttg tatcctggta cacctttagc aactgatata gttggaagtg
    19981 aggagtccat ttcccaaatc aatctaacta atttgcaaga aaattttaca aagttttaca
    20041 aacctgtaaa catgtctctg tttttagttg gtaattttga tgtggagcga gtacaggact
    20101 attttgaaag caaagaactg aaagattcag attttcagga agtagcaaga gaaaagttgt
    20161 ttttacagcc tgtaaagcca acagatagta tgagaatgga agtatcttct cccaaactag
    20221 cgattggagt tagaggtaag cgagaagttt ctgaagcgga ttgctatcga catcatattt
    20281 tattaaaatt attgtttgca atgatgtttg gttggacttc ggatcgtttt caaaaatgtt
    20341 atgaatcagg taaaattgat gcatccttat ctctggaagt tgaagtaaca agtcgctttc
    20401 attttgtcat gttgacaatg gatacgaaag agccagttgc tttgtctcat caatttagga
    20461 aggctattcg taattttaca aaggatttag atattacaga ggaacattta gatattatca
    20521 aaagagagat gtttggcgaa tttttcagta gcatgaactc tcttgaattt attgcaacgc
    20581 aatatgatgc ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt ttacaggaaa
    20641 ttactttaga ggatgtcctt gatgctggac atcatttaat agatgatggt gacatagttg
    20701 attttacaat attcccatcg tagtaaccta ttataataga cactagaaag aagggatgac
    20761 aagtatgaga aaaaaaacaa ttggagaggt tttacgatta gctagaatca atcagggatt
    20821 gagtttagat gaattgcaga aaaagacaga aatccagtta gatatgttgg aagcaatgga
    20881 agcagacgat ttcgatcaac ttccaagtcc tttttacacg cgttctttct tgaaaaaata
    20941 tgcatgggct gttgagttag atgaccaaat tgttttggat gcttatgatt ctgggagtat
    21001 gattacttat gaggaagtag atgttgatga agatgagttg acaggtcgta gacgttcaag
    21061 taagaaaaag aagaaaaaaa catcattttt acctttattt tattttatcc tttttgcttt
    21121 atcgatttta atttttgtga cttattatgt ttggaactat attcaaactc aaccagagga
    21181 gccttctctt tctaattaca gtgtggttca atcaacaagt tcaactagct ctgttcccca
    21241 ctcctcaagt agtagttctt ctagtataga atcagctata agtgtatcag gcgaaggaaa
    21301 tcatgtagaa atcgcttata agacaagtaa ggaaacagtt aaattgcaat tggcagtttc
    21361 agatgttaca agttgggtca gtgtttcaga aagcgaactt gagggcggtg taaccttatc
    21421 gccaaagaag aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa caattacgtt
    21481 aggtgttgta aaaggtgttg atttgacagt agataatcag actgttgatt tatcgaaatt
    21541 aacagctcag actggacaaa tcactgtaac ctttactaaa aattaaggaa aaacgaatga
    21601 aaaaagaaca aattcccaat ctcttaacaa taggtcgaat tctctttata cctattttta
    21661 tctttatttt aacgatagga aattcgatag agagtcatat agttgcagct attatctttg
    21721 ctgttgccag tattaccgac tatttagatg gatatttagc tcgtaaatgg aatgtggtca
    21781 gtaattttgg taaatttgca gatcctatgg cggataagtt actagttatg tcggctttta
    21841 ttatgttgat tgagttaggt atggctccgg cttggattgt tgcagtgatt atctgtcgtg
    21901 agttagctgt gacaggttta aggcttttat tggttgaaac tggtggaaca attttagcag
    21961 cagcaatgcc tggaaaaatt aaaactttta gtcagatgtt tgccattatt ttcttgctat
    22021 tacattggac tttgcttggt caagttctac tttatgtagc cttatttttc actatctact
    22081 ctggctatga ctatttcaag ggtagtgcct atgtatttaa agggacattt ggttcgaaat
    22141 gaaatcaata attgatgtaa aaaatctttc ttttcgctat aaagaaaatc agaactacta
    22201 cgatgtgaag gatattacgt ttcacgtgaa acgtggagaa tggctttcga ttgtagggca
    22261 taatggtagt ggtaaatcaa cgacggttcg attaattgat ggcttactgg aagcagaatc
    22321 cggagagatt gtaattgatg gccaacgttt gactgaggaa aatgtttgga atatacgtcg
    22381 tcaaatcggt atggtttttc aaaatccaga caatcaattt gttggagcga ctgttgaaga
    22441 tgatgttgct tttggtttgg aaaatcaggg actttctcgt caagaaatga aaaagagagt
    22501 agaagaagct ctggctttag ttggcatgtt ggactttaaa aagagagagc cagcgcgtct
    22561 atcaggtggc caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa gaccagctat
    22621 tttaatctta gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag aacttattgg
    22681 gacagtaaaa ggaattcgaa aagactatga tatgacggtc atttttatta cccatgattt
    22741 ggaagaagtc gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa ttgaatcaac
    22801 tagtagtcca agggagcttt tctctcgaaa tgatttagat caaattggat tagacgatcc
    22861 ttttgctaat caattaaaaa aatctttgag ccagaatggc tatgatttac ctgaaaatta
    22921 tttgacagaa agtgagctag aggataagct atgggaattg ctctagaaaa tgtgaatttt
    22981 acatatcaag aaggtactcc cttagcttca gcagctttgt cggatgtttc tttgacgatt
    23041 gaagatggct cttatacagc tttaattggg cacacaggta gtggtaaatc aactatttta
    23101 caactcttaa atggtttatt ggtaccaagt caagggagtg tgaggatttt tgatacctta
    23161 atcacctcga cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt tggcttggta
    23221 tttcagtttg ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt tgcttttgga
    23281 ccgcaaaatt ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga gaaactggct
    23341 ctggttggaa ttgatgaatc actttttgat cgtagtccgt ttgagctgtc agggggacaa
    23401 atgagacgtg ttgccattgc aggcatactt gccatggagc cagctatatt agtcttagat
    23461 gagccaacag ctggtctaga tcctctaggg agaaaagagt tgatgaccct gttcaaaaaa
    23521 ctccaccagt cagggatgac catcgtcttg gtaacgcatt tgatggatga tgttgctgaa
    23581 tatgcgaatc aagtctatgt aatggaaaag ggacgtttag taaagggggg caaaccaagt
    23641 gatgtctttc aagacgttgt ttttatggaa gaagttcagt tgggagtacc taaaattacg
    23701 gccttttgta aacgattggc tgatagaggc gtgtcattta aacgattacc gattaagata
    23761 gaggagttca aggagtcgct aaatggatag tatgattttg gggcgttata tcccagggga
    23821 ttcgattgtt caccgattgg atccacgtag caaattgctt gctatgatgc tactgatttt
    23881 gattgtgttt tgggctaata accccttgac gaatctgatt ctttttatag cgacagggat
    23941 atttattgcc ttgtcaggag tatctctttc attttttatt cagggcttga agtctatgtt
    24001 tttcttgatt gccttcacaa ctatttttca actatttttc atttctaatg ggaatgtttt
    24061 atttgaattt tcgtttgtga gaatcacgga ttatgctttg caacaagctg ggattatttt
    24121 ttgtcgcttt gtattgatta ttttcttttc aactttgtta accttaacaa ccatgccttt
    24181 aagtttggca tcagctgtcg aagctttatt agcaccttta aagcgtgtga aagttccagt
    24241 tcatgaaatt ggattgatgc tgtctatgag tttgcgtttt gtcccaacct tgatggatga
    24301 tacgactcgg attatgaatg cacagaaagc tcgtggagtg gattttggag aaggaagcat
    24361 cgttcaaaaa gtaaaggcga tgattcccat tttgattcct ctttttgcga caagtttaaa
    24421 acgtgcagat tccttggcta tcgctatgga agcgcgtggc tatcagggtg gaaaaggcag
    24481 aagtcaatac cgacaattga aatggactct gaaggatacg ctgaccattc ttgttattct
    24541 cgtacttggt tgttgtttat ttttcttaaa atcttagtag ctttcaggaa ttgataaaaa
    24601 gttactgtaa cagtttttga tataaaggta gggatatgaa ccgttttaaa aaatcaaaat
    24661 atgtcattat tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg acgacttatt
    24721 caagtacaat tgtgacaaaa ttaggagatg gaatctcatt ggttgataga gttgtacaaa
    24781 aaccttttca gtggtttgat tctgtcaaat cagatttggc tcatttgaca cgaacatata
    24841 atgaaaatga aagtttgaag aaacagcttt accaattaga agttaaatca aatgaggtgg
    24901 aaagtttaaa gacagaaaat gaacaactgc gccaattgct tgatatgaag tctaaattgc
    24961 aagccacaaa gactttagca gcagatgtta ttatgcgttc tccggtatct tggaagcagg
    25021 agttgacctt agatgcaggc agatcaaaag gtgcttctga gaacatgtta gctattgcaa
    25081 atggtggctt gattgggagt gtttcaaaag tagaggagaa ctctactata gtcaaccttc
    25141 tgacaaatac ggaaaatgct gataagattt ctgttaaaat tcaacatggc tctactacaa
    25201 tttatggaat tattattggc tatgacaagg aaaatgacgt tcttaaaatt agccaattaa
    25261 atagtaatag cgatattagt gcgggagata aggtgactac tggtggatta ggaaacttta
    25321 acgttgctga tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca gactatttga
    25381 cacgagaagt aactgttaaa ttgagtgcag atactcataa tgtagatgtg atagaattag
    25441 tggggaattc ataatgagac agttgaagcg agttggagta tttttattgc ttcctttctt
    25501 tgttctaatt gacgcccata ttagccagct tctgggctca tttttccccc atgtacattt
    25561 ggctagtcat tttctttttc tatttctctt atttgagacg atagaagtat cagagtatct
    25621 ctacctagtc tattgttttg ttataggctt ggtttatgat gtttactttt tccatctaat
    25681 agggattaca actctcttat ttatcttatt gggagccttc cttcataaat tgaatagtgt
    25741 tattttgttg aatcgttgga caagaatgct agctatgatt gtgctgacat tcctgtttga
    25801 aatgggtagt tatcttttgg cttttatggt agggttgaca gtagatagca tgtcgatttt
    25861 tatagtctat agcttggtac cgacgatgat tttaaatttt ttatggatta ctgtttttca
    25921 atttattttt gaaaaatatt atctataaga acgacatata aatgtaacaa aggcgtaata
    25981 tttattaggc ctttttttgg tatactagta ttgtctttaa aagaaggagt atctacgtaa
    26041 tatgaagaaa aaaatcttag cgtcactttt attaagtaca gtaatggttt ctcaagtagc
    26101 tgttttaaca actgcgcatg cagaaacgac tgatgacaaa attgctgctc aagataataa
    26161 aattagtaac ttaacagcac aacaacaaga agcccaaaaa caagttgacc aaattcagga
    26221 gcaagtatca gctattcaag ctgagcagtc taacttgcaa gctgaaaatg atagattaca
    26281 agcagaatct aagaaactcg agggtgagat tacagaactt tctaaaaaca ttgtttctcg
    26341 taaccaatcg ttggaaaaac aagctcgtag tgctcaaaca aatggagccg taactagcta
    26401 tatcaatacc attgtaaact caaaatcaat tacagaagct atttcacgtg ttgctgcaat
    26461 gagtgaaatc gtatctgcaa acaacaaaat gttagaacaa caaaaggcag ataaaaaagc
    26521 tatttctgaa aaacaagtag caaataatga tgctatcaat actgtaattg ctaatcaaca
    26581 aaaattggct gatgatgctc aagcattgac tacgaaacag gcagaactaa aagctgctga
    26641 attaagtctt gctgctgaga aagcgacagc tgaaggggaa aaagcaagtc tattagagca
    26701 aaaagcagca gctgaggcag aggctcgtgc agctgcggta gcagaagcag cttataaaga
    26761 aaaacgagct agccaacaac aatcagtact tgcttcagca aacactaact taacagctca
    26821 agtgcaagca gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc gtccaacata
    26881 cagtacaaac gcttcaagtt atccaattgg agaatgtaca tggggagtaa aaacattggc
    26941 accttgggct ggagactact ggggtaatgg agcacagtgg gctacaagtg cagcagcagc
    27001 aggtttccgt acaggttcaa cacctcaagt tggagcaatt gcatgttgga atgatggtgg
    27061 atatggtcac gtagcggttg ttacagctgt tgaatcaaca acacgtatcc aagtatcaga
    27121 atcaaattat gcaggtaatc gtacaattgg aaatcaccgt ggatggttca atccaacaac
    27181 aacttctgaa ggttttgtta catatattta tgcagattaa tttacagagg gactcgaata
    27241 gagccctctt ttcaggtttt accgtgacaa tccctattaa aaattatatc aaaatagctt
    27301 gaaaatattg gaaaagtatg gtagaatgaa aattgtcgtg tgaacgataa tactcattct
    27361 tgatgaattg tgaagcagtt gcccttgggt cgttttgcga gttgaagtca agaagaggaa
    27421 aaaaacaaaa aggagaaata ctcatggcag taatttcaat gaaacaactt cttgaggctg
    27481 gtgtacactt tggtcaccaa actcgtcgct ggaatcctaa gatggctaag tacatcttta
    27541 ctgaacgtaa cggaatccac gttatcgact tgcaacaaac tgtaaaatac gctgaccaag
    27601 catacgactt catgcgtgat gcagcagcta acgatgcagt tgtattgttc gttggtacta
    27661 agaaacaagc agctgatgca gttgctgaag aagcagtacg ttcaggtcaa tacttcatca
    27721 accaccgttg gttgggtgga actcttacaa actggggaac aatccaaaaa cgtatcgctc
    27781 gtttgaaaga aattaaacgt atggaagaag atggaacttt cgaagttctt cctaagaaag
    27841 aagttgcact tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggc ggtatcgaag
    27901 atatgcctcg tatcccagat gtgatgtacg tagttgaccc acataaagag caaatcgctg
    27961 ttaaagaagc taaaaaattg ggaatcccag ttgtagcgat ggttgacacc aatactgatc
    28021 cagatgatat cgatgtaatc atcccagcta acgatgacgc tatccgtgct gttaaattga
    28081 tcacagctaa attggctgac gctattatcg aaggacgtca aggtgaggat gcagtagcag
    28141 ttgaagcaga atttgcagct ttagaaactc aagcagattc aattgaagaa atcgttgaag
    28201 ttgtagaagg cgacaacgct taatttatac aaatagtaat tacctaggag ggcggggctt
    28261 agcccggctc tcctattttc aaaaaatata ggagaattaa aatggcagaa attacagcta
    28321 aacttgtaaa agagttgcgt gaaaaatctg gtgccggtgt tatggacgct aaaaaagcgc
    28381 ttgtagaaac agacggtgac atcgaaaaag cgattgaatt gcttcgtgaa aaaggtatgg
    28441 ctaaggcagc taagaaagct gaccgtgttg ctgcagaagg tttgactggt gtttatgtta
    28501 acggtaatgt tgcagcagtt attgaagtaa acgctgaaac tgacttcgtt gcaaaaaacg
    28561 ctcaattcgt tgaattggta aatactacag ctaaagtcat tgctgaagga aaacctgcta
    28621 acaacgaaga agctcttgct ttgataatgc cttcaggtga aactcttgaa gctgcatacg
    28681 tatctgcaac agcaactatc ggagagaaaa tctcattccg tcgctttgca ttgattgaaa
    28741 aaacagacgc acaacacttt ggagcatacc aacataacgg tggacgtatc ggtgttattt
    28801 cagttgttga aggtggagac gaagcacttg ctaaacaatt gtcaatgcac atcgcagcga
    28861 tgaaaccaac agttctttct tacaaagaat tggatgagca attcgttaaa gatgagttgg
    28921 cacaattgaa tcacgttatc gaccaagaca acgaaagccg tgcaatggtt aataaaccag
    28981 ctcttccaca cttgaagtat ggatcaaaag ctcaattaac tgatgatgtt attgctcaag
    29041 ctgaagctga catcaaagct gaattggctg cagaaggcaa accagaaaaa atctgggaca
    29101 aaattattcc aggtaaaatg gatcgcttca tgcttgataa cactaaagtt gaccaagctt
    29161 acacacttct tgcacaagtt tacatcatgg atgacagcaa gacagttgaa gcataccttg
    29221 aatcagttaa cgcttcggta gttgagtttg ctcgctttga agttggtgaa ggtatcgaga
    29281 aagctgcaaa cgacttcgaa gctgaagttg cagctacaat ggcagcagcc ttgaataact
    29341 aataatagaa aggaagcaaa ttgcttcctt ttttgtatag ggcttagatt tttcctgaaa
    29401 ttgttttttc cccagtctca ctcgattaga ataattaaaa caaaaagccc tataataagg
    29461 gctaagtgca tttaggagac tatacttcaa attcatagta agcgcgtcat aacaaggtat
    29521 ctatcctaat tccccaactt ccagtatact agataaaaaa taattatcgg aggaaaggta
    29581 ttgtactatg ataattcaac taagtgattt aggtcaagtt caccttgttt gtggcaagac
    29641 agatatgagg cagggaatag actcattagc ctatgtagtt aaaacccact ttgaattgga
    29701 ttctttctcc ggtcaagtct ttctcttttg tggtggacgt aaagaccgct ttaaagccct
    29761 ttactgggat ggtcaaggat tttggctact atataaacgc tttgagaacg gaaaactgac
    29821 ttggctaagt acagaaaagg atgtcaaagc tctcgcacct gaacaagtag actagcttat
    29881 gaagggcttt tctatcactc caaaaatata gtagattgaa actagaatag tacacctctg
    29941 cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttgtcc tgttcttatt
    30001 tcattttact ataaatccat cagaaagtcg tgatttctat tgaaatgagg actttctttt
    30061 tacactcatc tgctttcaaa aagcattcta gtccgtctcc gattaacgat ggactttatc
    30121 acctccttct ccagtccttg tatgacatct tccaaagttc gaaaggcttt attcttaaat
    30181 ccacgtttac gaatctcttt ccacacttgt tcaatggggt tcatctctgg tgtgtatgga
    30241 ggaataaatg aaaagccaat attagtcgga atctttaagg tacttgattt atgccatata
    30301 gcattgtcca taacgagtaa aagataatca tctggataag cttgtgaaag ctcctattcc
    30361 taaagcccct ttagcgcata actttggctc agcttctatt atcgctcaca ccatccatca
    30421 gaagtttaat ctgaaggtac ccaattatcg ccaagaagaa ggttgggcta ggatgggttt
    30481 accaatcaca cgtaaggaaa ttgttaattg gcatatcaag gcgagtcaat actatttgga
    30541 gcccctttat aacctcttgc gagagagact attgacgcag tccttacttc atgcggatga
    30601 aacttcttat agggtgctag agagtgatag tcagctgact tactattgga cttttttgtc
    30661 tgggaaagct gagaaacaag ggattacgct ttaccatcat gtcctaatcg atttgttcat
    30721 atcttatttc aatccattat aaatagtgag aaatatctat cctatcttct agaatgtctt
    30781 ccaaacgtgg aaactctcgt aaacaaagag gttttagagg cctatttacc atggactaaa
    30841 gttgtacaag aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttctct
    30901 agtctggaga tttttcaata gacttcgtta ttggatggtt acaattcata aagtgctgta
    30961 gagagataac gttcaccgtt atctggtgct agggcaagga cttttttacc tgtacctaat
    31021 tttttggcaa cctcaatggc tccgtagata gctgcagctg aggaaatccc tacaaggaag
    31081 ccttcttttc caccaatttc acgtccgagt gcaagagcgt catctgatgt tacacgaacg
    31141 ataccatcat aggctttagt atcaagtgta tcaggaataa atccagctga gataccttga
    31201 attttgtgag gaccaggttt ttcaccagat agaatagcag attcatctgc ttctactgca
    31261 aaaacttgaa tgttagaatt ttctgatttg agtgcatgag aaacaccaga aatcgttcca
    31321 ccggtaccta ctccagcaac aaaggcatct aatccatctt taccgaaagc agctagtatc
    31381 tcagctcctg ttgttctttc gtgtacttct ggattagctg gattgtcaaa ttgaagagga
    31441 aggaaaccat cacgttcagc agcgatttct tgagccttag caatagcacc tttcattccc
    31501 tcgctaccag gagttaggac gagttcagca ccataagctt ggataatttt acgtcgttct
    31561 acactcatag tttcaggcat aacgatgacg actttatacc ctttagcagc acctacccat
    31621 gaaagtccaa taccagtgtt tccacttgtt gcttcaacaa tagtagaacc aggtttcaga
    31681 ataccatctt gttcagcttt ttcaatcatg ctaagggcaa tacggtcttt tacagatgaa
    31741 ccaggattaa atgcttcaag ctttatatag acgtctgcag caccttctgg cacgatgttg
    31801 ttaagtttaa caatcggtgt ttgaccgatt aattcagtaa tgttgttata aatagacata
    31861 tgaatacctc tttgtataag atatctttag tataacgcta tccataccat ttgtaaaata
    31921 tagaaatcct atcgaagcga taggatttct atatatcata gatcaaagtc attaattttc
    31981 aagtgattgc gttcagctaa ttctagtaaa taggtgtgaa ggaaaacgat atcaggtttc
    32041 gtttgaattg cttcattttc tagtatattt tggtacgcat ctttttattt tgctcgctaa
    32101 agtagttgtg agaatgtcaa cgaaacgctg tattattcat tgtttacact aagtttacag
    32161 gaacttcaac ctctcgtaaa ccttggtcag ttaaagtgac ttttccatta aaaaactcca
    32221 caagtgcagc tttaatagtt tctttttctt ctttatcaac ataaatcatc gtatcgactt
    32281 gatctgtaaa gtttgtatcc agctccatga gatcatgttc tttaaggaag ttactgtact
    32341 cttggtactg agcataagac atttgaatag caatgccagc ctgttctttt atttcaataa
    32401 taccaatttc tttgacagct aaggcgacac tgccggcgta agcacgaatt agtcctccag
    32461 cgcctagttt aataccacca aagtagcgtg tcacgaccac acagacattg gtgagattgt
    32521 gattttctag taccccaagc atgggaacac cagcagtacc actaggctca ccatcatcac
    32581 ttgtacgttt aatttcacta cgttctccaa taataaaggc agagcagtta tgtgtcgctt
    32641 tgtagtgttc ttttttgatg gcagtaatga agtcacgagc ctcttcttcg ctataaacac
    32701 gcttggcatg gcagataaag cgagattttt tgatttcttc ttggacttga ccgtcctctt
    32761 taattgtcct aaattccatg atttaattgt actaaaaaat catctaaagt gctagttttt
    32821 acgaataaag aagtatgaaa gtaaatttag attatctcgg tcgtttattt actgagaatg
    32881 aattaacaga agaagaacgt cagttggcgg agaaacttcc agcaatgaga aaggagaagg
    32941 ggaaactttt ctgtcaacgc tgtaatagta ctattctaga agaatggtat ttgcccatcg
    33001 gtgcttacta ttgtcgagag tgcttgctga tgaagcgagt cagaagtgat caaactttat
    33061 actattttcc gcaggaggat tttccaaagc aagatgttct caaatggcgc ggccaattaa
    33121 ctccttttca agagaaggtg tcagagggat tgcttcaagt agtagacaag caaaagccaa
    33181 ccttagttca tgcggtaaca ggagctggaa agacagaaat gatttatcaa gtagtggcta
    33241 aagtgatcaa tgcgggtggt gcagtgtgtt tggctagtcc tcgcatagat gtttgtttgg
    33301 atctgtacaa gcgcctgcaa caggattttt cttgcgggat agctttgcta catggagaat
    33361 cggaacctta ttttcgaaca ccactagttg ttgcaacaac ccatcagtta ttgaagtttt
    33421 atcaagcttt tgatttgctg atagtggatg aagtagatgc ttttccttat gttgataatc
    33481 ccatgcttta ccacgctgtc aagaatagtg taaaggagaa tggattgaga atctttttaa
    33541 cagcgacttc gaccaatgag ttagataaaa aggtccgttt aggagaacta aaaagactga
    33601 atttaccgag acggtttcat ggaaatccgt tgattattcc aaaaccaatt tggttatcgg
    33661 attttaatcg ctacttagac aagaatcgtt tgtcaccaaa gttaaagtcc tatattgaga
    33721 agcagagaaa gacagcttat ccgttactca tttttgcttc agaaattaag aaaggggagc
    33781 agttagcaga aatcttacag gagcaatttc caaatgagaa aattggcttt gtatcttctg
    33841 taacagagga tcgattagag caagtacaag cttttcgaga tggagaactg acaatactta
    33901 tcagtacgac aatcttggag cgtggagtta ccttcccttg tgtggatgtt ttcgtagtag
    33961 aggccaatca tcgtttgttt accaagtcta gtttgattca gattggtgga cgagttggac
    34021 gaagcatgga tagaccgaca ggagatttgc ttttcttcca tgatgggtta aatgcttcaa
    34081 tcaagaaggc gattaaggaa attcagatga tgaataagga ggctggtcta tgaagtgctt
    34141 gttatgtggg cagactatga agactgtttt aacttttagt agtctcttac ttctgaggaa
    34201 tgatgactct tgtctttgtt cagactgtga ttctactttt gaaagaattg gggaagagaa
    34261 ctgtccaaat tgtatgaaaa cagagttgtc aacaaagtgt caagattgtc aactttggtg
    34321 taaagaggga gttgaagtca gtcatagagc gatttttact tacaatcaag ctatgaagga
    34381 ttttttcagt cggtataagt ttgatggaga cttcctgtta agaaaagttt tcgcttcatt
    34441 tttaagtgag gagttgaaaa agtacaaaga gtatcaattt gttgtaattc ccctaagtcc
    34501 tgatagatat gctaatagag gatttaatca ggttgagggc ttggtagagg cagcaggctt
    34561 tgagtatctg gatttattag agaaaagaga agagagagcc agttcttcta aaaatcgttc
    34621 agagcgcttg gggacagaac ttcctttctt tattaaaagt ggagtcacta ttcctaaaaa
    34681 aatcctactt atagatgata tctatactac aggagcaact ataaatcgtg ttaagaaact
    34741 gttggaagaa gctggtgcta aggatgtaaa aacattttcc cttgtaagat gaggaaaaaa
    34801 tttgcaaaaa cagaatgaaa gcgttataat aaaatcataa aaacaaaaat gtttagaaag
    34861 aaggtactca tatgattaaa tatagtatcc gtggtgaaaa cctagaagta acagaagcaa
    34921 ttcgtgatta tgtagtttct aaactcgaaa agatcgaaaa gtacttccaa ccagaacaag
    34981 agttggatgc ccgaattaac ttaaaagttt atcgtgaaaa aacggctaaa gtggaagtaa
    35041 cgattccgct tggatctatt actctccgcg cagaagatgt atctcaagat atgtatggtt
    35101 caattgacct tgtaactgat aaaattgaac gtcagattcg taaaaataaa acaaaaatcg
    35161 agcgtaaaaa taaaaataag gtagcaactg gtcaattatt tacagatgct ttggtggaag
    35221 attcaaatgt tgtccagtct aaagttgttc gttcaaaaca aattgattta aaaccaatgg
    35281 atttggaaga agcaattcta caaatggatt tattggggca tgatttcttt atctatgtgg
    35341 atgttgaaga tcagacaacc aatgtgattt atcgtcgtga ggatggcgaa attggtttgt
    35401 tagaggttaa agaatcttaa tttcaatatg tgtaaaggta ggtttactga attgtaaact
    35461 acctttttct tataattgat agaattactg attacacttt taaaaagtcg ctttttgagg
    35521 ggtattatgg tataatgggt gccaagaggt tttgaatgaa aaaattttat gtaagtccaa
    35581 tttttcctat tctagtagga ttgattgcgt ttggagtctt atccactttc attatttttg
    35641 ttaataataa tctgttgacg gttttaattt tgtttctttt tgtaggaggc tatgtttttt
    35701 tatttaagaa actgagagtg cattatacaa ggagtgatgt agaacagata cagtatgtaa
    35761 accaccaagc ggaagaaagt ttgacatctc tattggaaca aatgcctgta ggtgttatga
    35821 aattgaattt atcttctgga gaggttgagt ggtttaatcc ctatgctgaa ttgattttga
    35881 ccaaggaaga tggtgatttt gatttagaag ctgttcaaac gattatcaag gcttcagtag
    35941 gaaatccgtc tacttatgcc aagcttggtg agaagcgtta tgctgttcat atggatgctt
    36001 cttccggtgt tttgtatttt gtagatgtat ccagggaaca agccataaca gatgaattgg
    36061 taacaagtcg accagtgatt gggattgtct ctgtggataa ttatgatgat ttggaggatg
    36121 caacttctga gtcagatatt agtcaaatca atagttttgt agctaatttt atatcagagt
    36181 tttcagaaaa atacatgatg ttttctcgtc gggtaagtat ggatcgattt tatctattta
    36241 ctgactacac ggtgcttgag ggcttgatga atgataaatt ttctgttatt gatactttca
    36301 gagaagagtc gaaacagaga cagttgccct tgaccttaag tatgggattt tcttatggcg
    36361 atggaaatca tgatgagata gggaaagttg ctttgctcaa tttgaacttg gctgaagtac
    36421 gtggtggcga ccaggtggtt gttaaggaaa acgacgaaac gaaaaatcca gtttattttg
    36481 gtggtgggtc tgctgcttca atcaagcgta cacggactcg tacgcgcgct atgatgacag
    36541 ctatttcaga taagattcgg agtgtagatc atgtttttgt agtcggtcac aaaaatttag
    36601 acatggatgc tttgggctct gctgtaggta tgcagttgtt cgccagcaat gtgattgaaa
    36661 atagctatgc tctttatgat gaagaacaaa tgtctccaga tattgaacga gctgtttcat
    36721 tcatagaaaa agaaggagtt acgaagttgt tgtctgttaa ggatgcaatg gggatggtga
    36781 ccaatcgttc tttgttgatt cttgtagacc attcaaagac agccttaaca ttatcaaaag
    36841 aattttatga tttatttacc caaaccattg ttattgacca ccatagaagg gatcaggatt
    36901 ttccagataa tgcggttatt acttatatcg aaagtggtgc aagtagtgcc agtgagttgg
    36961 taacggaatt gattcagttc cagaattcta agaaaaatcg tttgagtcgt atgcaagcaa
    37021 gtgtcttgat ggctggtatg atgttggata ctaaaaattt cacctcgcga gtaactagtc
    37081 ggacatttga tgttgctagc tatctcagaa cgcgcggaag tgatagtatt gctatccagg
    37141 aaatcgctgc gacagatttt gaagaatatc gtgaggtcaa tgaacttatt ttacaggggc
    37201 gtaaattagg ttcagatgta ctaatagcag aggctaagga cacgaaatgc tatgatacag
    37261 ttgttattag taaggcagca gatgccatgt tagccatgtc aggtattgaa gcgagttttg
    37321 ttcttgcgaa gaatacacaa ggatttatct ctatctcagc tcgaagtcgt agtaaactga
    37381 atgtacaacg gattatggaa gagttaggcg gtggaggcca ctttaatttg gcagcagctc
    37441 aaattaaaga tgtaaccttg tcagaagcag gtgaaaaact gacagaaatt gtattaaatg
    37501 aaataaagga aaaggagaaa gaagaatgaa agtaatcttt ttagcagatg ttaaaggaaa
    37561 aggtaaaaaa ggcgaaatta aggaagtacc aacagggtat gcgcaaaact ttcttatcaa
    37621 aaagaatcta gccaaagaag cgactgctca agctgtaggt gaacttcgtg gtaaacaaaa
    37681 atcggaagaa aaagctcacg ctgagatgat tgcagaaggg aaagcaatta aagcacaact
    37741 tgaagcagaa gaaactgttg tagaatttgt tgaaaaagtt ggtccagatg gtcgtacctt
    37801 tggttctatt accaataaga agattgcaga agaattacaa aagcaatttg gaattaagat
    37861 tgataaacgt catattcaag tacaagctcc gattcgagcg gttggtttga ttgatgtgcc
    37921 agtgaaaatc tatcaagata tcacaagtgt aatcaatctt cgtgtgaaag aaggataagt
    37981 ttacaccttc ttgacaagat tgtaaaagga agggaagtct gatggcagaa gtagaagagt
    38041 tacgagtaca acctcaagat atcttagctg agcaatccgt tttaggggct atctttattg
    38101 atgagagtaa acttgttttt gtgcgagaat acattgagtc tcgggacttt tttaagtatg
    38161 cccatcgttt gattttccaa gccatggtcg atttatccga tcgtggtgat gccatagatg
    38221 caacaacggt tcgtactatc cttgataatc aaggtgattt acagaatatt ggtggcttgt
    38281 cttacttggt tgagattgtc aattctgtgc caacttctgc taatgcggag tattatgcta
    38341 agattgttgc agaaaaagca atgctacgtc gtttaattgc caagttgaca gagtctgtca
    38401 accaagctta cgaagcgtca caaccagctg atgaaattat tgctcaggca gaaaaagggc
    38461 tgattgatgt cagtgaaaat gcaaatcgaa gcgggtttaa gaacattcga gatgtgttga
    38521 atctcaactt tggaaatctg gaagctcgct cgcaacaaac gaccgatatt acaggtattg
    38581 cgacaggtta tcgtgatttg gatcatatga caacaggact tcatgaggag gagttgatta
    38641 tcttagcagc tcgtccagca gttggtaaga cagcatttgc cttgaatatc gctcagaata
    38701 ttgggactaa gttggacaaa acggttgcta ttttttcact cgaaatgggt gcggaaagct
    38761 tggtagaccg tatgttagct gcagaaggct tggtggagtc acattctatc cgtacagggc
    38821 aattgacaga tgaggagtgg caaaaatata ctattgctca gggtaatcta gctaacgcca
    38881 gtatctatat cgatgatacg ccaggtattc ggattacaga gattcgttct cgttctcgta
    38941 aattggctca agaaactgga aatcttggtt tgattttgat agactatttg caacttatca
    39001 cgggaactgg tcgagaaaat cgtcaacaag aagtttctga aatttctcgt cagttgaaaa
    39061 tactagccaa ggaattgaag gttccagtaa tcgctctgag tcagctttct cgtggtgtag
    39121 aacaacgtca ggacaagaga ccggtcttgt ctgatattcg tgaatctggg tctattgagc
    39181 aggacgctga tatcgtagct tttctctatc gcgatgacta ctatgaacgt ggtggtgaag
    39241 aagaggaggg tatcccaaat aataaggtgg aagttattat cgagaaaaac cgtagtggag
    39301 ctcgtggaac agtggaattg attttccaaa aagaatacaa taaattttca agtatctcaa
    39361 agagggaggc ataagatgtc agatgcattt acagatgtag ccaagatgaa aaaaatcaaa
    39421 gaagaaatca aggcacatga gggacaagtc gtagaaatga ctttggagaa tggtcgtaag
    39481 cgccaaaaaa atagattggg taagctaatt gaagtttatc catccctatt tattgtggag
    39541 tttggggatg tggaaggaga taaacaagtt aatgtttacg ttgaatcctt tacttactca
    39601 gatattctta cagaaaagaa tttgattcat tatcttgact aaagtgagaa attttctcac
    39661 tttttctttt ttctccgaat aatttaggtg aaggcaatca tcgctttata ttatttttta
    39721 aggaggaaga atgaaaattt taccgtttat agcaagagga acaagttatt acttgaagat
    39781 gtcagttaaa aagcttgttc cttttttagt agtaggattg atgctagcag ctggtgatag
    39841 tgtctatgcc tattccggag gaaatggatc gattgcgcgt ggggatgatt atcctgctta
    39901 ttataaaaat gggagccagg agattgatca gtggcgcatg tattctcgtc agtgtacttc
    39961 ttttgtagcc tttcgtttga gtaatgtcaa tggttttgaa attccggcag cttatggaaa
    40021 tgcgaatgaa tggggacatc gtgctcgtcg ggaaggttat cgtgtagata atacaccgac
    40081 gattggttcc attacttggt ctactgcagg aacttatggt catgttgcct gggtgtcaaa
    40141 tgtaatggga gatcagattg agattgagga atataactat ggttatacag aatcctataa
    40201 taaacgaatt ataaaagcaa acacgatgac aggatttatt cattttaaag atttggatgg
    40261 tggcagtgtt gggaatagtc aatcctcaac ttcaacaggc ggaactcatt attttaagac
    40321 caagtctgct attaaaactg aacccctagt tagtgcaact gtgattgatt actattatcc
    40381 tggagagaag gttcattatg atcaaattct cgaaaaagac ggctacaagt ggttgagtta
    40441 tactgcctat aatggaagct atcgttatgt tcaattggag gctgtgaata aaaatcctct
    40501 aggtaattct gttctttctt caacaggtgg aactcattat tttaagacca agtctgctat
    40561 caaaactgaa cccctagtta gtgcaactgt gattgattac tattatcctg gggagaaggt
    40621 tcattatgat cagatacttg aaaaagacgg ctacaagtgg ttgagttata cggcttataa
    40681 cggaagtcgt cgctatatac agctagaggg agtgacttct tcacaaaatt atcagaatca
    40741 atcaggaaat atctctagct atggatccaa taatagttca actgtcggtt ggaagaaaat
    40801 aaatggtagt tggtatcatt tcaaatcaaa tggttctaaa tcaacaggat ggctgaaaga
    40861 tggttctagc tggtattatt tgaaattatc tggtgaaatg cagacaggat ggttaaagga
    40921 gaatggctcg tggtattatc tgggtagttc aggggcaatg aaaacaggct ggtaccaggt
    40981 ctctggtaag tggtattatt cttactcttc aggcgcctta gctgttaata cgacggtgga
    41041 tggctacaga gtaaacagtg atggagaacg agtatagaaa attggagtag gagaaatttc
    41101 ctgctctttt ctgtaagcag tttccttgac atttttctta ttttgcgcta tcatatatac
    41161 atataatata tgggagtctg tgtacagtct gagaggaagt gttaaacttc gaccgcacct
    41221 gatctgggta atgccagcgg agggaacgat acttagtcta attttgcacc ttttccatgt
    41281 atggtaaagg tttttctttt ttttaaaagg aaaacgagaa gaggaggttc ttatgaaagc
    41341 aagcattgcc ttgcaagttt tacccctagt acaggggatt gatcggatag ctgttattga
    41401 tcaggtcatt gcttatctgc aaactcaaga agtgccgatg gtagtgacac catttgaaac
    41461 ggtcttggaa ggggagtttg atgagcttat gcgcattcta aaagaagcgc tggaagtggc
    41521 agggcaggag gcagacaatg tctttgccaa tgtcaaaata aatgtaggag agattttaag
    41581 tattgatgag aaacttgaga agtatactga gacgacacat tagtctattg ggctttctcg
    41641 gagtcttgtc aatctggcag ttagcaggtt ttcttaaact gctccccaag tttatcctgc
    41701 cgacacctct tgaaattctc cagccctttg ttcgtgacag agaatttctc tggcaccata
    41761 gctgggcgac cttgagagtg gctttactgg ggctgatttt gggagttttg attgcctgtc
    41821 ttatggctgt actcatggat agtttgactt ggctcaatga cctgatttac cctatgatgg
    41881 tggtcattca gaccattccg accattgcca tagctcctat cctggtcttg tggctaggtt
    41941 atgggatttt gcccaagatt gtcttgatta tcttaacgac aacctttccc atcatcgtca
    42001 gcattttgga cggttttagg cattgcgaca aggatatgct gactttgttt agtctgatgc
    42061 gggccaagcc ttggcaaatc ctgtggcatt ttaaaattcc agtcagcctg ccctactttt
    42121 atgctggtct gagggtcagt gtctcctacg cttttatcac aacagtggta tctgagtggt
    42181 tgggaggctt tgaggggctt ggtgtttata tgattcagtc caagaaattg tttcagtatg
    42241 ataccatgtt tgccattatt attctggtgt cgattatcag tcttttgggt atgaagctgg
    42301 tcgatatcag tgaaaaatat gtgattaaat ggaaacgtac ttaaaataga gcgtttttga
    42361 aaaagaaaag aggaaatcaa aatgaagaaa acatggaaag tgtttttaac gcttgtaaca
    42421 gctcttgtag ctgttgtgct tgtggcctgt ggtcaaggaa ctgcttctaa agacaacaaa
    42481 gaggcagaac ttaagaaggt tgactttatc ctagactgga caccaaatac caaccacaca
    42541 gggctttatg ttgccaagga aaaaggttat ttcaaagaag ctggagtgga tgttgatttg
    42601 aaattgccac cagaagaaag ttcttctgac ttggttatca acggaaaggc accatttgca
    42661 gtgtatttcc aagactacat ggctaagaaa ttggaaaaag gagcaggaat cactgccgtt
    42721 gcagctattg ttgaacacaa tacatcagga atcatctctc gtaaatctga taatgtaagc
    42781 agtccaaaag acttggttgg taagaaatat gggacatgga atgacccaac tgaacttgct
    42841 atgttgaaaa ccttggtaga atctcaaggt ggagactttg agaaggttga aaaagtacca
    42901 aataacgact caaactcaat cacaccgatt gccaatggcg tctttgatac tgcttggatt
    42961 tactacggtt gggatggtat ccttgctaaa tctcaaggtg tagatgctaa cttcatgtac
    43021 ttgaaagact atgtcaagga gtttgactac tattcaccag ttatcatcgc aaacaacgac
    43081 tatctgaaag ataacaaaga agaagctcgc aaagtcatcc aagccatcaa aaaaggctac
    43141 caatatgcca tggaacatcc agaagaagct gcagatattc tcatcaagaa tgcacctgaa
    43201 ctcaaggaaa aacgtgactt tgtcattgaa tctcaaaaat acttgtcaaa agaatacgca
    43261 agcgacaagg aaaaatgggg tcaatttgac gcagctcgct ggaatgcttt ctacaaatgg
    43321 gataaagaaa atggtatcct taaagaagac ttgacagaca aaggcttcac caacgaattt
    43381 gtgaaataat gacagaaatt agactagagc acgtcagtta tgcctatggt caggagagga
    43441 ttttagagga tatcaaccta caggtgactt caggcgaagt ggtttccatc ctaggcccaa
    43501 gtggtgttgg aaagaccacc ctctttaatc taatcgctgg gattttagaa gttcagtcag
    43561 ggagaattgt ccttgatggt gaagaaaatc ccaaggggcg cgtgagttat atgttgcaaa
    43621 aggatctgct cttggagcac aagacggtgc ttggaaatat cattctgccc ctcttgattc
    43681 aaaaggtgga taaggcagaa gctatttccc gagcggataa aattcttgcg accttccagc
    43741 tgacagctgt aagagacaag tatcctcatg aacttagcgg tgggatgcgc cagcgtgtag
    43801 ccttactccg gacctacctt tttgggcaca agctctttct cttagatgag gcctttagcg
    43861 ccttggatga gatgacaaag atggaactcc acgcttggta tcttgagatt cacaagcagt
    43921 tgcagctaac aaccctgatc atcacgcata gtattgagga ggccctcaat ctcagcgacc
    43981 gcatctatat cttgaaaaat cgccctgggc agattgtttc agaaattaaa ctagattggt
    44041 ctgaagatga ggacaaggaa gtccaaaaga ttgcctacaa acgtcaaatt ttggcggaat
    44101 taggcttaga taagtagaaa aatagggagt tggtgaagat tatcctttac cagcgccctt
    44161 tttcttttaa aaatgagaaa atttcggtat aatagtcaaa caaggtcaag gtttaaagag
    44221 agaggtgggt ttgttatgag atttaaaaat acatcggatc atattgaggc ctacatcaag
    44281 gcgattttag atcaatctgg tatcgtggag ttgcaacgga gtcagttggc agataccttt
    44341 caggttgttc ctagtcagat taactacgtg atcaagacac gctttacgga aagtagaggc
    44401 tacttggttg aaagtaagcg tggtggcgga ggctacattc gtataggacg gattgagttt
    44461 tctagtcatc atgaaatgct ccgggagctg ctttactcga ttggtgagcg agtcagtcaa
    44521 gaaatttatg aggatattct ccagcttttg gttgagcagg aattgatgac caagcaggag
    44581 atgaatttgc tagaatcagt agctttggat cgcgttttag gagaagaagc tccagttgtt
    44641 cgagcaaaca tgctacgtca gatcatacaa gaggtagata gaaaagggaa gtaagatgaa
    44701 ctattcaaaa gcattgaatg aatgtatcga aagtgcctac atggttgctg gacattttgg
    44761 agctcgttat ctagagtctt ggcacttgtt gattgccatg tctaatcaca gttatagtgt
    44821 agcaggggca actttaaatg attatccgta tgagatggac cgtttagaag aggtggcttt
    44881 ggaactgact gaaacggact atagccagga tgaaaccttt acggaattgc cgttctcccg
    44941 tcgtttgcag gttctttttg acgaagcaga gtatgtagcg tcagtggtcc atgctaaggt
    45001 gctagggaca gagcacgtct tctatgcgat tttgcatgat ggcaatgcct tggcaactcg
    45061 tatcttggag agggctggtt tttcttatga agacaagaaa gatcaggtca agattgctgc
    45121 tcttcgtcga aatttagaag aacgggcagg ctggactcgt gaagatctca aggctttacg
    45181 ccaacgccat cgtacagtag ctgacaagca aaattctatg gccaatatga tgggcatgcc
    45241 gcagactcct agtggtggtc tcgaggacta tacgcatgat ttgacagagc aagcgcgttc
    45301 tggcaagtta gaaccagtca tcggtcggga caaggaaatc tcacgtatga ttcaaatctt
    45361 gagccggaag actaagaaca accctgtctt ggttggggat gctggtgtcg ggaaaacagc
    45421 tctggcgctt ggtcttgctc agcgtattgc tagtggtgac gtgcctgcgg aaatggctaa
    45481 gatgcgcgtg ttagaacttg atttgatgaa tgtcgttgca gggacacgct tccgtggtga
    45541 ctttgaagaa cgcatgaata atatcatcaa ggatattgaa gaagatggcc aagtcatcct
    45601 ctttatcgat gaactccaca ccatcatggg ttctggtagc ggaattgatt cgactctgga
    45661 tgcggccaat atcttgaaac cagccttggc gcgtggaact ttgagaacgg ttggtgccac
    45721 cactcaggaa gaatatcaaa aacatatcga aaaagatgcg gcactttctc gtcgtttcgc
    45781 taaagtgacg attgaagaac caagtgtggc agatagtatg actattttac aaggtttgaa
    45841 ggcgacttat gagaaacatc accgtgtaca aatcacagat gaagcggttg aaacagcggt
    45901 taagatggct catcgttatt taaccagtcg tcacttgcca gactctgcta tcgatctctt
    45961 ggatgaggcg gcagcaacag tgcaaaataa atcaaagcat gtaaaagcag acgattctga
    46021 cttgagtcca gctgacaagg ccttgatgga tggcaagtgg aaacaggcag cccagctaat
    46081 cgcaaaagaa gaggaagtgc ctgtctataa agacttggtg acagagtctg atattttgac
    46141 caccttgagt cgcttgtcag gaatcccagt tcaaaaactg actcaaacgg atgctaagaa
    46201 gtatttaaat cttgaagcag aactccataa acgggttatc ggtcaagatc aagctgtttc
    46261 aagtattagt cgtgccattc gccgcaatca gtcaggaatt cgcagtcaca agcgtccgat
    46321 cggttccttt atgttcctag gacccacagg tgtcggtaag accgagttgg ccaaggcttt
    46381 ggcagaagtt ctctttgatg acgaatcagc ccttatccgc tttgatatga gtgagtatat
    46441 ggagaaattc gcagccagcc gtctaaatgg agctcctcca ggctatgtgg gttacgaaga
    46501 aggtggggag ttgacagaga aggttcgcaa taaaccctat tccgttctcc tctttgatga
    46561 ggtagagaag gcccatccag atatctttaa tgttctcttg caggttctgg atgacggtgt
    46621 cttgacagat agcaagggac gcaaggtcga tttttcaaat accattatca ttatgacatc
    46681 gaacttaggt gcgactgccc ttcgtgatga taagactgtt ggttttgggg ctaaggatat
    46741 tcgttttgac caggaaaata tggaaaaacg catgtttgaa gaactgaaaa aagcttatag
    46801 accggaattc atcaaccgta ttgatgagaa ggtggtcttc catagcctat ctagtgacca
    46861 tatgcaggaa gtggtgaaga ttatggtcaa gcctttagtg gcaagtttgg ctgaaaaagg
    46921 cattgacttg aaattacaag cttcagctct gaaattgtta gcaaatcaag gatatgaccc
    46981 agagatggga gctcgcccac ttcgcagaac cctgcaaaca gaagtggagg acaagttggc
    47041 agaacttctt ctcaagggag atttagtggc aggcagcaca cttaagattg gtgtcaaagc
    47101 aggccagtta aaatttgata ttgcataaaa gaataaaagt atcagcatct gaccataagt
    47161 cacagtggag tgaaactcaa tgaaaatcaa agagcaaact aggcagctag ccgcaggttg
    47221 ctcaaaacac tgttttgagg ttgcagatag agctgacgtg gtttgaagag attttcgaag
    47281 agtatgaaac taaaacctat agcttctaaa cgatccgtgg ttttcaccat tcaacacaaa
    47341 attcatatgt ttattaccct ccgtcgtatt tgtcttagag cgtgtgtagt agaaaaagag
    47401 cagtcttatc tgaaattttt attctttcaa aagagacctg tttctttttt gcatgtcaaa
    47461 tccgttctag ctggtatttg aaaaatcaaa ctaatactca atgaaaatca aagaacaaac
    47521 taggaagcta gccgcaggtt gctcaaaaca ctgttttgag gttgtagata gagctgacgt
    47581 agtttgaaga gattttcgaa gagtataagc tgcaagatga atgattttct tgtattgacg
    47641 ttgttgttga caaaaagtag cggataaatg aaatccattc cattatcata gatgataggc
    47701 tggtaggaaa ttttcaaata gcatacagga aatagatgta tggagttctg gtagtagaaa
    47761 gggagagaga tgaacatttt agttgcagat gacgaggaaa tgattagaga aggaattgca
    47821 gcatttctga cagaagaggg ttatcatgtc attatggcta aggatggaca agaggtcttg
    47881 gaaaaatttc aagatctccc tatccatctc atggtactgg atttaatgat gcctaggaag
    47941 agtggttttg aagtgttaaa agaaatcaat caaaagcacg atattcctgt catcgtcttg
    48001 agtgctctgg gagatgaaac tactcagtca caggtatttg atctctatgc tgatgatcat
    48061 gtgacaaaac ctttttcttt ggtactgctt gtcaagcgta ttaaggcgct tatcagacgt
    48121 tactacgtca tagaggatct ttggcgatat caggatgtaa cagtggattt tacctcttac
    48181 aaagcacatt ataaaaatga agaaattgat ctcaaaccaa aggaattact ggtactaaag
    48241 tgtttgattc agcataaaaa tcaagtttta agtagagagc agatattgga agaaatttca
    48301 aaagatgtag ctgatttacc ttgtgatagg gtcgttgatg tctatattcg tactcttcgc
    48361 aaaaaattag ctttagattg tatcgtgact gtgaaaaatg ttgggtataa gattagctta
    48421 tgataaaaaa tcctaaatta ttaaccaagt cttttttaag aagttttgca attctaggtg
    48481 gtgttggtct agtcattcat atagctattt atttgacctt tcctttttat tatattcaac
    48541 tggaggggga aaagtttaat gagagcgcaa gagtgtttac ggagtattta aagactaaga
    48601 catctgatga aattccaagc ttactccagt cttattcaaa gtccttgacc atatctgctc
    48661 accttaaaag agatattgta gataagcggc tccctcttgt gcatgacttg gatattaaag
    48721 atggaaagct atcaaattat atcgtgatgt tagatatgtc tgttagtaca gcagatggta
    48781 aacaggtaac cgtgcaattt gttcacgggg tagatgtcta caaagaagca aagaatattt
    48841 tgcttttgta tctcccatat acatttttgg ttacaattgc tttttccttt gttttttctt
    48901 atttttatac taaacgcttg ctcaatcctc ttttttacat ttcagaagtg actagtaaaa
    48961 tgcaagattt ggatgacaat attcgttttg atgaaagtag gaaagatgaa gttggtgaag
    49021 ttggtgaagt tggaaaacag attaatggta tgtatgagca cttgttgaag gttattcatg
    49081 agttggaaag tcgtaatgag caaattgtaa aattgcaaaa tcaaaaggtt tcctttgtcc
    49141 gcggagcatc acatgagttg aaaacccctt tagccagtct tagaattatc ctagagaata
    49201 tgcagcataa tattggagat tacaaagatc atccaaaata tattgcaaag agtataaata
    49261 agattgacca gatgagccac ttattagaag aagtactgga gtcttctaaa ttccaagagt
    49321 ggacagagtg tcgtgagacc ttgactgtta agccagtttt agtagatatt ttatcacgtt
    49381 atcaagaatt agctcattca ataggtgtta caattgaaaa tcaattgaca gatgctacca
    49441 gggtcgtcat gagtcttagg gcattggata aggttttgac aaacctgatt agtaatgcaa
    49501 ttaaatattc agataaaaat gggcgcgtaa tcatatccga gcaagatggc tatctctcta
    49561 tcaagaatac atgtgcgcct ctaagtgacc aagaactaga acatttattt gatatattct
    49621 atcattctca aatcgtgaca gataaggatg aaagttccgg tttgggtctt tacattgtga
    49681 ataatatttt agaaagctat caaatggatt atagttttct cccttatgaa cacggtatgg
    49741 aatttaagat tagcttgtag acagattagt tttttattaa a
//
LOCUS       DAVLTT010000009        48612 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLTT010000009 DAVLTT010000000
VERSION     DAVLTT010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48612
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.009"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(213..1199)
                     /locus_tag="VYN15_000573"
     CDS             complement(213..1199)
                     /locus_tag="VYN15_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1451937.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1209..2009)
                     /locus_tag="VYN15_000574"
     CDS             complement(1209..2009)
                     /locus_tag="VYN15_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV1451938.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2262..3104)
                     /locus_tag="VYN15_000575"
     CDS             complement(2262..3104)
                     /locus_tag="VYN15_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1451939.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLYTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3106..4398)
                     /locus_tag="VYN15_000576"
     CDS             complement(3106..4398)
                     /locus_tag="VYN15_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1451940.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4509..5780)
                     /locus_tag="VYN15_000577"
     CDS             complement(4509..5780)
                     /locus_tag="VYN15_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1451941.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6330..7847
                     /gene="malQ"
                     /locus_tag="VYN15_000578"
     CDS             6330..7847
                     /gene="malQ"
                     /locus_tag="VYN15_000578"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV1451942.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            7873..10131
                     /gene="glgP"
                     /locus_tag="VYN15_000579"
     CDS             7873..10131
                     /gene="glgP"
                     /locus_tag="VYN15_000579"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV1451943.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGENSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11176..11748)
                     /locus_tag="VYN15_000580"
     CDS             complement(11176..11748)
                     /locus_tag="VYN15_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451944.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGIYLAQLWDKNDAIPNNGRINF"
     gene            complement(12369..13217)
                     /locus_tag="VYN15_000581"
     CDS             complement(12369..13217)
                     /locus_tag="VYN15_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1451945.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13369..13647
                     /locus_tag="VYN15_000582"
     CDS             13369..13647
                     /locus_tag="VYN15_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451946.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13649..15712
                     /locus_tag="VYN15_000583"
     CDS             13649..15712
                     /locus_tag="VYN15_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1451947.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15790..17046)
                     /locus_tag="VYN15_000584"
     CDS             complement(15790..17046)
                     /locus_tag="VYN15_000584"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV1451948.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17188..19650
                     /locus_tag="VYN15_000585"
     CDS             17188..19650
                     /locus_tag="VYN15_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1451949.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSRARR"
     gene            19715..20626
                     /locus_tag="VYN15_000586"
     CDS             19715..20626
                     /locus_tag="VYN15_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1451950.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            20856..21554
                     /gene="dapD"
                     /locus_tag="VYN15_000587"
     CDS             20856..21554
                     /gene="dapD"
                     /locus_tag="VYN15_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV1451951.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21622..22752
                     /locus_tag="VYN15_000588"
     CDS             21622..22752
                     /locus_tag="VYN15_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV1451952.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22764..23303
                     /locus_tag="VYN15_000589"
     CDS             22764..23303
                     /locus_tag="VYN15_000589"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV1451953.1"
                     /translation="MKSELRKQVLQGMKAISQEQKQFIDQTLTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDLQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23287..23964
                     /locus_tag="VYN15_000590"
     CDS             23287..23964
                     /locus_tag="VYN15_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV1451954.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIILRYATRNPYIQQLGQSYMTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRLYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(24031..24930)
                     /gene="galU"
                     /locus_tag="VYN15_000591"
     CDS             complement(24031..24930)
                     /gene="galU"
                     /locus_tag="VYN15_000591"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV1451955.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDEATGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMNDYEKTHAST
                     IAVMPVPHEDVSSYGVIAPQDEGKDGLYSVETFVEKPAPEETPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFARKFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(24952..25968)
                     /locus_tag="VYN15_000592"
     CDS             complement(24952..25968)
                     /locus_tag="VYN15_000592"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1451956.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVAVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            26180..26561
                     /locus_tag="VYN15_000593"
                     /pseudo
     CDS             26180..26561
                     /locus_tag="VYN15_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(26735..27160)
                     /locus_tag="VYN15_000594"
     CDS             complement(26735..27160)
                     /locus_tag="VYN15_000594"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1451957.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(27228..27878)
                     /gene="phoU"
                     /locus_tag="VYN15_000595"
     CDS             complement(27228..27878)
                     /gene="phoU"
                     /locus_tag="VYN15_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1451958.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(27893..28645)
                     /gene="pstB"
                     /locus_tag="VYN15_000596"
     CDS             complement(27893..28645)
                     /gene="pstB"
                     /locus_tag="VYN15_000596"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1451959.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(28647..29462)
                     /gene="pstA"
                     /locus_tag="VYN15_000597"
     CDS             complement(28647..29462)
                     /gene="pstA"
                     /locus_tag="VYN15_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1451960.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(29455..30318)
                     /gene="pstC"
                     /locus_tag="VYN15_000598"
     CDS             complement(29455..30318)
                     /gene="pstC"
                     /locus_tag="VYN15_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1451961.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(30436..31311)
                     /locus_tag="VYN15_000599"
     CDS             complement(30436..31311)
                     /locus_tag="VYN15_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV1451962.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(31478..32809)
                     /locus_tag="VYN15_000600"
     CDS             complement(31478..32809)
                     /locus_tag="VYN15_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV1451963.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(32810..33517)
                     /locus_tag="VYN15_000601"
     CDS             complement(32810..33517)
                     /locus_tag="VYN15_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1451964.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(33601..34086)
                     /locus_tag="VYN15_000602"
     CDS             complement(33601..34086)
                     /locus_tag="VYN15_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1451965.1"
                     /translation="MAPTDKEDLIRTLELAPHIEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVVPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            34072..34629
                     /locus_tag="VYN15_000603"
                     /pseudo
     CDS             34072..34629
                     /locus_tag="VYN15_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(34944..36635)
                     /locus_tag="VYN15_000604"
     CDS             complement(34944..36635)
                     /locus_tag="VYN15_000604"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV1451966.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            36771..37217
                     /gene="argR"
                     /locus_tag="VYN15_000605"
     CDS             36771..37217
                     /gene="argR"
                     /locus_tag="VYN15_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1451967.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            37268..39802
                     /gene="mutS"
                     /locus_tag="VYN15_000606"
     CDS             37268..39802
                     /gene="mutS"
                     /locus_tag="VYN15_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV1451968.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     VSSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKST
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            39949..41643
                     /gene="patA"
                     /locus_tag="VYN15_000607"
     CDS             39949..41643
                     /gene="patA"
                     /locus_tag="VYN15_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV1451969.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(41973..42236)
                     /locus_tag="VYN15_000608"
                     /pseudo
     CDS             complement(41973..42236)
                     /locus_tag="VYN15_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            42434..44200
                     /gene="patB"
                     /locus_tag="VYN15_000609"
     CDS             42434..44200
                     /gene="patB"
                     /locus_tag="VYN15_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV1451970.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            44339..45028
                     /locus_tag="VYN15_000610"
     CDS             44339..45028
                     /locus_tag="VYN15_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1451971.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            45032..45211
                     /locus_tag="VYN15_000611"
     CDS             45032..45211
                     /locus_tag="VYN15_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451972.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            45198..46547
                     /locus_tag="VYN15_000612"
     CDS             45198..46547
                     /locus_tag="VYN15_000612"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV1451973.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            46671..48131
                     /locus_tag="VYN15_000613"
     CDS             46671..48131
                     /locus_tag="VYN15_000613"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV1451974.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELVAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            48145..48543
                     /locus_tag="VYN15_000614"
     CDS             48145..48543
                     /locus_tag="VYN15_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1451975.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNTYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYW"
BASE COUNT        14339 a         9230 c        10525 g        14518 t
ORIGIN      
        1 tatccacaac ctcaaaacag tgttttgagc aacctgcggc tagcttccta gtttgcactt
       61 tgattttcat tgagtataaa aagatcttgg gaaaagactc aatttcagta gaaaaggaag
      121 taaatcttcc cacaataaaa cgcatagtat caagtttttt caatacctga tagtatgcgt
      181 tttttgcttt taacgacttt ttgcccagtc tcttattttt cgataatttt gtgggcgatc
      241 aattgacggt aacaaatttg tttattgttt ttattatcat taataatctg gagaatagtt
      301 tcaagggaaa cacgaccaag ctctaaacta ttgatatcga cataggctgc caagttgagc
      361 ttgggattaa ccgagtcaaa gctgagaaca gggacatcca gctggtgttt ggcaatatag
      421 ttacaaacac cttcagctag gaggctatcg gttgtgatga tagcatcaat ttgtggatcg
      481 tgcttgaata atcgcttgct aaatttatag cccttttctt ccagaaactc gtcggcaaag
      541 tagatgcgat tgttgtcagt ggtaagtttg taatgtttaa gcgcctgttc atagcctgtt
      601 aaacggtctt tggtcacgaa gagcttttta cttcctccga taaaggcaat gcgtttgcag
      661 ccttttttga tgaaatattc agtcgcatca aaaccagctt gaacattgtc gttgtcgaca
      721 agtgggatga aaggagatag agatttacct aagataagga aggggaactg ttcttctgcg
      781 acgagtttta cgagagggtc ttcttcttgg gcatagagaa agattagccc atctacacgc
      841 ttgccgtaga ccatttgtga aatagcgttg agacgctcct tctcatcttt ccctgttgct
      901 atctgaatgg catagtggtt ttcagatgcg acttgagaga tgccacgtag aaccgatgga
      961 aagaaaggat tctggtagaa ggcgtctgag tcatcaggaa gaactaatcc gataacctga
     1021 gtatagctgc ttaccaagct acgagcgttg aggtttgggt ggtagttgag ttccttcata
     1081 gctttgcgaa cgcgtttttt tgtttcgtcg ctaatggttg atttattttg aataacacgg
     1141 gttacggttg aaggcgaaac accagcagcc ttggccacgt ctttaatcgt aacgggcata
     1201 aaaatctcct atttatggta atttggatca cggaaatgtg ttttataaaa gatagtgacc
     1261 agatacagaa caaaaagaat attttgtaca gtaatcaggg ttgtcatatt ttggccaaat
     1321 aatcccaaaa taagtgtaat cagagtcggc aatcctaaac agttcaagat aaagtgatag
     1381 cactctttaa aggttctaaa tgaaaagagg cgtgatttct tagtgatata aaggagaaga
     1441 ctagctccta gagagacgat aaagaaattc aaaccaaaga ggaagctcgc accgagaact
     1501 aggaagaggc tgatatagac acgattttgt tggtaccagt ctttagaaat tgcttgggtc
     1561 aagctgtctt tgcttttgaa actctcagtc tgaatggctc ggtaagagat gcgggtcagt
     1621 tccttgcttt ccttgctgat gactagttca tttgtatcga aatgcagttg caagtcctta
     1681 ggtaattcct tgatttgact tggaccaatc acaacagaag gggcttgact agctgttcca
     1741 gtataagtta atgtgccatc gacaattgta gcatgttcag agagatcctg gacaacctta
     1801 tctgtcagag gttcatagac attatcgata aaagtttcta gcggataggt ctcctgggag
     1861 ctgttttgga tagcaatggg taccatagac aagctgataa ggaagatact ggtaaagaga
     1921 agttgaaacc agttgagctc gaaacgtttg gacaggggct tacgaaaccc ccaaatactt
     1981 gaaaaatagg aaaatggata tggaagcata ggtatctttc taaaaggtgt tttctatatg
     2041 agtattatta tatagagaaa tgcgctttat ttcaagtcta ggagaaaaat tgcttgctac
     2101 aaggatatta tttacagtga caattgctaa taatcaatga aaatcaaagt gcaaactagc
     2161 cacaggttgc tcaaagcaca actttgaggt tggagataaa gctgacgtgg tttgaagaga
     2221 ttttcgaaga gtataaaatg aaaaagggtg gcggggataa attatccctt gtcgccacca
     2281 cttgtaagtc ctgaaacaaa gttcttttgt aggaagaaga agagaataca gattggaagg
     2341 gcgatgagga tagcacctgc tgagaagtag gcaatcttca agtttttcgc attgttaacg
     2401 aaggtttgga gacctacggc aacagtaaag tattctttct cacgaagcaa gaaactagag
     2461 aggatgtagt ccccgaaagg tcccatgaag gcccagagag cttgtacggc aaccattggg
     2521 cgaacaagtg gtagaacaat ttgccagaag cggcggaagt gtcctgcacc gtctagtttt
     2581 gcagattcgt ctaaagacat tggcactgta tcgaagtagc ctttcatgag ccaagcattc
     2641 atcgggatac caccaccaac gtagaggaag atgaggaacc agttgtggtt aagggcgttc
     2701 aacataagcg ccataacgaa gaaggctgtc aaagcggcca tagttggcac catttggatg
     2761 attaagaaga agaccaaact ttgtttacga gccaagaagt tgtaacggct gtaagcataa
     2821 ccagcaagta cgatgatact tgtttgaaca gccatggtaa ttaaggcgat aatcaaagtg
     2881 ttgaggtacc aagtaccgta caaggtttca gtgaagaggc ctttaaagtt atcaaaattg
     2941 aggtcgatat tagtatatag tttaaaggct gagacgttac ctgctttaaa ggctgacata
     3001 atggtaatca acagtggata gataattaca attgatagac caatcaggta aaggtaagta
     3061 aggctttgag tcagtctacg tttgagttta attgagttat tcatcttaga cgtcctccat
     3121 atcaaatgcg tgtagtttct tgaatgcgat catagagatt gagatgacaa tgatagagat
     3181 aatcaaggta acagctgccg ccattgagta ttgaggagat gtacctgttg tcaaacggta
     3241 gatccatgag atcaagatat cggttgaacc agctccacct ccgacactac caggtcctcc
     3301 accattgaag aggtacatga tagagaagtt gttaaagttg aaggtgtatt ggctaatcaa
     3361 agtaggtgcc gcaacagcca aaatcattgg gaaagtgatg ttgcggaatt tttgccaagc
     3421 gttggcaccg tcaatataag ctgcttcgta aaggtcgtta ggaatagatt gcaagatacc
     3481 caaagtcaaa acgtagatgt atgggaatcc gagccaacct tgcatcataa tcaaggcaat
     3541 cttagtccaa gttgggtctg ttttccaagg aataagagct ccatcaagga aaggaaggaa
     3601 tttagccaag attggcaata cttgagtgtt gatagcaccg acactatcgt taaacatatt
     3661 tgagaatgtc aagatagtga tgaaggctgg gacagcccaa ggaagaagga aaataacacc
     3721 aaagatacgt tttcctttga taaatggttg gttggcaatg atagctgtga agataccaat
     3781 tacgatttgt aaagtagaag ctgccaaagc ccaaatgata gtccaagaaa gaacagaacc
     3841 aaaggcagaa cggaaggtac tcaagctcca aatgtttgta aagttggtca aaccaaccca
     3901 gtccaacaac ttgtttggtg gcaagtgttg gaagtcgtag ttggtaaagg cgatcatcaa
     3961 ggttacgata actgggaaga taatcgcgaa ggtcatggca acataagatg gaatgatcaa
     4021 gaggtaaggg aagccatttt cataaatccc tttgatcatg tctttgagtg tgcgtggaac
     4081 tggaattcca ttgttaatgc gttttgcaat cgtatgtgca tctttgatat ttgagaaata
     4141 aaagagtaca taaacgatta caaagattag atggaaggca ccacgaatca gcataaagag
     4201 ggaattatca cgacctggtt tgtcaccaag agtgatgagg ttgctcaatt caggggttgc
     4261 aagtgctagg aagtaaagga caaatacgat ggttacacca aggaagataa aacctttggc
     4321 tttttgttta ttgtaaatct gtcctaaccc aggaatgata gacagcaggg ctgctttact
     4381 aggttgttgc ttttccatat taactccttt cataggatac tactttttta taagaaagct
     4441 aaattatttg tgtctctatt gataaattca aagggggatt tgatttccac cccccttgaa
     4501 caaatttttt attcaccaaa tttttgtttg attgtttctt tgatcaatgt tacagcatcg
     4561 ttagcagctg ttttagcatc tttttgacca cttacagcat caaagagcat atttttcgct
     4621 ggatcccaaa ctgcagacat ttgagagatg tttggcagtg gttgagtgtt cttgaactgt
     4681 ttgataacag ctgttgtcaa ctcatcgttt ttaccttcag cgtatgaacg agcctcagta
     4741 ttagctggga tttcgttagt cttatcatat aatacttttt gttgttcagt tgcaacaagg
     4801 aagtctacaa atttttgaga agcttcaagg ttcttaacgg cttgaggaat gacccaagct
     4861 ttaccaccac cgaatgcagc atattctttt ccatttggaa gagttgggat agttgcaact
     4921 ccgtagttta ctttagcatc tttaaaggct tgagctttcc aaggtccgtc gatgatagca
     4981 gctgttttac cttcttggaa ttgagtttgg attaagtttc cagcaccttc tgtatcttgc
     5041 atacctttag gccatttttc gtaccaagat ttagcgtagt tgatacctgc gatagaaccg
     5101 tcgtttgcaa gaccgatgtc tttagcgtct ttaccgtttt ggccaaagac gtaagcaccg
     5161 ttaccggcaa gaagtccata tgtatagtag aagtttgtcc agtcagctag gaaggcagta
     5221 gttttaccat cttcaccagc gaatgcgtat ttgctatctt tagcaaggtt ttccaagtca
     5281 gcaaatgttt ttggagcatc tttcaccaag tctttgttgt agtacataac aagtgactcg
     5341 ataacggcag gagcaccgta aactttacca ttagcagctg ttacaagaga tttagttgtg
     5401 tcgtctgttt tagcaccatc gctcaatttc acttctgaaa gttgtccgtc agaaccaagg
     5461 ctacctacac ggtcgtatgg agccatcata acatcaggga cattaccaga ttggttgtca
     5521 agagaaagtt tatcaagacc tcctagagca tcaccagttt taagagtgac ttttactcca
     5581 gcttcttttt cataagcttt agcaacctct tcaatatagc tcttatatcc ctcgtctaca
     5641 tatacagtga gttctttgac ttcagatgaa ccagaatcag caggcttatc agcagttttg
     5701 cttccgcaag ctaccaaaag caagctagca agtgtaacag ttccaagcac cgcagtgctc
     5761 ttcataaatt tagatgacat agtgtattcc tcccaaagaa tagcaagttt tattgataag
     5821 gaaacgcaaa cgttttcctt tatgagctta gtatagcaca aatagaaaac ggttgcaagt
     5881 attttttgta aaaattttaa aaaattttta agcttgattt gatagcataa ttttgcattt
     5941 taatagaaga aaagtatgaa atagataaga atacagtatt tttaataaaa atatatggaa
     6001 tctgtctaaa gagggaaacc aggaggggct acctccctgg ttctaatccc tatctatttt
     6061 ctatggacgt ttgtgctttg ttacatataa attcaagctc cctaaggagg ttttgtactt
     6121 tgtagactgt ctcgtgagag tcaaacctta ggattagata gttttaagtt atctttgcta
     6181 aaatgagtta gtctccttaa aaataatcaa aaaagttttt taaaaacgct tgcaattatg
     6241 cttgaaaagg agtatactta taagtaacgc aaacgtttgc gtctgcaaaa tacgcaacgt
     6301 tccattattt taacacacga ggtgctatta tgaaaaaacg tcaaagtggt gtgttgatgc
     6361 acatctcttc tcttccagga gcttacggaa tcggatcatt tggtcaaagt gcttacgact
     6421 tcgttgattt cttggtccgt acaaaacaac gttactggca aatccttcca ttaggagcaa
     6481 ctagttacgg ggattctcct taccaatctt tctcagcctt cgcaggaaac actcatttta
     6541 tcgatttaga tatcttggtg gagcaaggtt tgttggaagc aagtgacctt gaaggagttg
     6601 actttggtag cgatgcgtct gaagttgact atgctaaaat ctactatgca cgtcgtcctc
     6661 ttttagaaaa agctgtgaaa cgtttctttg aagtcggaga tgttaaagat tttgagaaat
     6721 ttgctcaaga caaccaatca tggcttgagc tctttgctga gtatatggct atcaaagagt
     6781 attttgacaa tcttgcttgg actgaatggc cagatgcaga tgctcgtgct cgtaaagctt
     6841 cagcacttga aagctatcgt gagcaattgg cagacaagtt ggtttaccac cgtgtgactc
     6901 aatacttctt cttccaacaa tggttgaaat tgaaagctta cgctaacgac aaccacatcg
     6961 aaatcgttgg ggacatgcca atctacgtag cggaagattc aagtgatatg tgggcaaatc
     7021 cacatctctt caaaacagat gtcaatggta aggctacttg tatcgcagga tgcccaccag
     7081 atgagttttc tgtaactggt cagctttggg gtaacccaat ctatgactgg gaagcaatgg
     7141 acaaagacgg ctacaaatgg tggattgaac gcttgcgtga aagcttcaaa atctacgata
     7201 tcgttcgtat cgaccacttc cgtggcttcg aatcttactg ggaaatccct gctggttccg
     7261 atacagcagc acctggtgag tgggtgaaag gtccaggcta caagcttttt gcagccgtta
     7321 aggaagaact tggtgagcta aacatcatcg cagaagacct tggcttcatg acagatgaag
     7381 tgatcgaatt gcgtgaacgt actggcttcc caggaatgaa gattcttcaa tttgccttca
     7441 acccagaaga cgaaagcatt gatagcccac acttggcacc tgctaactca gttatgtaca
     7501 caggaacaca cgataacaat acggttcttg gttggtaccg taatgagatt gatgatgcga
     7561 ctcgtgagta catggctcgt tacacgaacc gtaaagaata cgaaacagtg gtacacgcta
     7621 tgcttcgtac agtattttca tcagttagct ttatggcaat tgcaactatg caagatttac
     7681 tagaattgga tgaggcagct cgtatgaact tcccatctac ccttggtgga aactggtctt
     7741 ggcgtatgac tgaagatcaa ttgacaccag ctgtcgagga aggtttgctt gacttgacaa
     7801 caatttatcg ccgaattaat gaaaatttgg tagatttaaa gaaataagac aataatcagg
     7861 agacaactaa acatgttatc actacaagaa tttgtacaaa atcgttacaa taaaaccatt
     7921 gcagaatgta gcaatgaaga gctttacctt gctcttctta actacagcaa gcttgcaagc
     7981 agccaaaaac cagtcaacac tggtaagaaa aaagtttact acatctcagc tgagttcttg
     8041 attggtaaac tcttgtcaaa caacttgatt aaccttggtc tttacgacga tgttaaaaaa
     8101 gaacttgcag ctgcaggtaa agacttgatc gaagttgaag aagttgaatt ggaaccatct
     8161 cttggtaatg gtggtttggg acgtttggct gcctgcttta tcgactcaat tgctactctt
     8221 ggtttgaatg gtgacggtgt tggtcttaac taccactttg gtcttttcca acaagttctt
     8281 aaaaacaacc aacaagaaac aattccaaat gcatggttga cagagcaaaa ctggttggtt
     8341 cgctcaagcc gtagctacca agtaccattt gcagacttta ctttgacatc aactctttac
     8401 gatattgatg ttactggtta tgaaacagcg actaaaaacc gcttgcgttt gtttgacttg
     8461 gattcagttg attcttctat tattaaagat ggtatcaact ttgacaagac agatatcgct
     8521 cgcaacttaa ctctcttcct ttacccagat gatagtgacc gtcaaggtga attgctccgt
     8581 atcttccaac aatacttcat ggtttcaaac ggtgcgcaat tgatcatcga cgaagcaatc
     8641 gaaaaaggaa gcaacttgca tgaccttgct gactacgcag ttgtccaaat caacgatact
     8701 cacccatcaa tggtgattcc tgaattgatt cgtcttttga ctgcacgtgg tatcgatctt
     8761 gacgaagcaa tctcaattgt tcgtagcatg actgcctaca ctaaccacac aatccttgct
     8821 gaagcgcttg aaaaatggcc tcttgaattc ttgcaagaag tggttcctca cttggtacca
     8881 atcatcgaag aattggaccg tcgtgtgaag gcagagtaca aagatccagc tgttcaaatc
     8941 atcgatgaga gcggacgtgt tcacatggct cacatggata tccactacgg atacagtgtt
     9001 aacggggttg cagcactcca tactgaaatc ttgaaaaatt ctgagttgaa agccttctac
     9061 gacctttacc cagaaaagtt caacaacaaa acaaacggta tcactttccg tcgttggctt
     9121 atgcatgcta acccaagatt gtctcactac ttggatgaga ttcttggaga tggttggcac
     9181 catgaagcag atgagcttga aaaactgttg tcttatgaag acaaagcagc tgtcaaagaa
     9241 aaattggaaa gcatcaaggc tcacaacaaa cgtaaattgg ctcgtcactt gaaagaacac
     9301 caaggtgtgg aaatcaatcc aaattctatc tttgatatcc aaatcaaacg tcttcacgag
     9361 tacaaacgcc aacaaatgaa cgctttgtac gtgatccaca aataccttga catcaaagct
     9421 ggtaacatcc ctgctcgtcc aatcacaatc ttctttggtg gtaaagcagc tccagcctac
     9481 acaatcgctc aagacattat ccatttaatc ctttgcatgt cagaagttat tgctaacgat
     9541 ccagcagtag ctccacactt gcaagtagtt atggttgaaa actacaacgt tactgcagca
     9601 agtttcctta tcccagcatg tgatatctca gaacaaatct cacttgcttc taaagaagct
     9661 tcaggtactg gtaacatgaa attcatgttg aacggagctt tgacacttgg tactatggac
     9721 ggtgctaacg tggaaatcgc tgagttggtt ggagaagaaa acatctacat cttcggtgaa
     9781 aattcagaaa ctgttatcga cctttacgca aaagcagctt acaaatcaag cgaattctac
     9841 gctcgtgaag ctatcaaacc attggttgac ttcatcgtta gtgatgcagt tcttgcagct
     9901 ggaaacaaag agcgcttgga acgtctttac aatgaattga tcaacaaaga ctggttcatg
     9961 actcttcttg atttggaaga ctacatcaaa gtcaaagagc aaatgcttgc tgactacgaa
    10021 gaccgtgacg catggttgga taaagtcatc gttaacattt ctaaagcagg attcttctca
    10081 tctgaccgta caatcgctca gtataacgaa gacatctggc acttgaacta atactcttcg
    10141 aaaatctctt caaaccacgt cagctttatc tgcaacctca aagcggtgct ttgagcaacc
    10201 tgcggctagc ttcctagttt gctctttgat tttcattgag tataagatac aaatttatac
    10261 taatacatct tgtaaaaaag cgagtttcaa ttgaaattcg cttttttaaa tgctgtggat
    10321 ttgggtcaat cttgtctaaa aatagggaaa tcctagatac agtgaaggct ttaaatgctg
    10381 gtttttactg tcttcagcct tatatttttt cgtagttggt tacctcacat ctattatatt
    10441 cgcttacata aagtattata atataattgt aggaaagaag gtgtttttat gatatacaca
    10501 cttaaattgg tgttgtttat tacctttctt gtaataagct tgttacctga taagattttt
    10561 ggaaaaaata aaaaaatttg gaaaatagtt tttgcaatat tgacggcagt ggcagcattg
    10621 tcatttatgt actaagttat tttaagaatg tagggaaata aaccctacat tttttttagt
    10681 tttttctgtt ttctaaattc tatttatcca agagcttcaa catttcttgc ttcttcgctt
    10741 caagttctgc acgcttttct tcgatttcgg catgtttttt ctcgagttca gaacaacttg
    10801 catcattgct aaattctttt cgccatcagg agatagggtg agtctacatg tctattactc
    10861 acccaaagca gtcctacaaa gcaggaattt tctgttactt ttttggaaat agtaacgttt
    10921 atacagcttt gacacttcgt atcaaagcgc caaacacact ccgagggatt tacagaaagc
    10981 agaaaaggaa tgatctggta taagatcatt ccttttctct ctttttcttt aagtaattat
    11041 atacaatgta cgacgaagtc gtcattgcaa tgctgatcca ccacctaaag ggaactttaa
    11101 acaacattga taagataaag aatataaaca acgaaaatac gttataccca attaatttta
    11161 ttgtatatct catgattaaa agttaatcct tccgttgtta ggaatggcat catttttatc
    11221 ccataattgt gctaaataaa tccccggtga taataaattc atagcgaatt ctaaagcaac
    11281 atcatttaca aaccaactac ctagatatct agaaattgct gaacgaatag cactttttgc
    11341 tgcatgtttt ccttttactt taattagatt tgcaaggcct gcagtagttc ctcctaatgc
    11401 taaagctatt gcagtatcta atagagcacc catttgatta actgtaatac cttgccaagc
    11461 tgctctaaat ggagagtatg taggtgggat tgtataatcg ccttgtaatt gtcggttaat
    11521 tacttctttg atccattgtt gtgagacgtc tggatgaaaa gattggattt cgtttgcaag
    11581 tgtattgatt tgttcttctg ttagagaagt gacaggttga agttccatat ttgtttcaat
    11641 ttgtgatact tgttcagaag cgtatacagc tgaaacactt ggaatcgctg atacaattaa
    11701 cacaattgac gtcaaaaaaa ccgaaataaa tttcattaat ttgttcatga gcttttctcc
    11761 tttttatttg tatctgctta cattttatca tatactgtta ttatagtcaa aaaaatatgc
    11821 tattatgtta aaaaatattt ttcaaaatat aaatggacgg atttattttg gattttattt
    11881 gttattttga cctgcctcta tattggtaac catgatttgt ttactctcaa tcatcaagaa
    11941 ttctcttttc gtggtagcgt ttggggtctg gtactggcct tatatcactt attgttcatt
    12001 gataagtttg taatttcgaa tcgaaaataa agattagaac tatgattgac tggctacttt
    12061 taatattgat tttggaggaa gattttgtct ctattattta ttattttaaa tttatctatt
    12121 ttgtacaaga tttattcttt gagacgggag aaatcgaaat acttgattta tacggcctat
    12181 atcatatttg gggtaaatgt agtatatggt attcaatggt tattaagaga actgatttca
    12241 actatttccc cttaatgtgt atggaaacta taacaaaacg cataagatta aggtttgtgt
    12301 acctgttctt atgcgttttt ataatattga agattttcgg taagttttat acctttggga
    12361 agtctagttt agaatgcttt cccaaccaaa atctctgctt cgatggtaat ctctgtcagt
    12421 tggctccagt caatcttgct ctggtcaacg tgaaagagga gaggagtcat actgagtagg
    12481 gcttggagtt gttctgctgt gatagtctta gtcagagagg cagtttgact agataggatg
    12541 gtaaagtgtt cctggaaatg ctccttgata tcttggttag aatactcctt gtttgtcagc
    12601 tggtcctgta ctctttgacg gatttctttg aggtgatttt cagttgggat aacctttatc
    12661 aagataccgt ctttggataa aacgcgacga aattctccat agttggcagg tgagaagata
    12721 tcaagcagaa tatccatgtt agcgtctttt ataggaagtc gtgccaagtc gccaacaaac
    12781 caattgactg cccagttggg ttcactttta gcagcgattt ggactgaatc tttggagatg
    12841 tcaaaggcat agaaagtttt ttcagagtga ctttcttgta gtttgcgaga atagaatcct
    12901 tcaccacaac cgatatccaa aattgttgtg gtagtttttg agcttgcaag caagtcagat
    12961 acagcatcta agatagcttg gtaaaagccg gcttctagga tttgttgacg gttttgaaaa
    13021 ttttccttgt tatagttagc agattgcttg atttgaggtg ctagattgac atagccaaat
    13081 ttcgccaagt caaaagaatg acggttgcag cacttgaaat tagtctctaa cagagtcaga
    13141 ttttcttgac agataggaca ggcaaaggca gtcgcagaag caaaacgctg aagtttgggc
    13201 ttgagatttg tattcatagt ttaagtgtat caaaagaggc aaatgaaagc aactttagga
    13261 ataagtagat gggagattca gtagaaataa aactaattct ccaatttata gaatgaaatt
    13321 gcttttatat ctaaattgct atataataat gataaggagg aaataagtat gttaaaagaa
    13381 gtattaaccg ttgcaaaagt tgcgaaaaaa tcttcattat ttttgggtgg tgtcgcattt
    13441 ggtacccttg gtttgaaaat cttagcaagt aaggaagcta aaaaaggtta ttctaaagct
    13501 ttggctaagg cttacaagtt gaaagacgag ctagatgcat ctgtttctgt tgtgaagcaa
    13561 catggagacg atgtcttgca agatgccaaa tatttgtacg agcaagagaa aaaagaagag
    13621 caattagata gccttatagg tgaataatat gtcttttaaa gtgctacata gaggatacca
    13681 acatatccga ctatcatctt ctttttcact taccttggat attcaagact atcttcgttc
    13741 cttggcgaga gatgaaaagg ggattgagtc tatccagttt tacatggatc aacagcactt
    13801 tactctacgc ataaaagaag gcttttctgt attagataat gcagaagcct ttttaaaaag
    13861 aattgataaa gggaaagttt ctgagttgat gactcttccc attcgtagag aagagagtgc
    13921 ttattctatt gtttcaggtg cagcggttaa gcgtgtactt tttcgtagtt ttgtgccgta
    13981 tcctattcgc tatatatgga cttgttatca ggctttgggt tatattagag aagcctatca
    14041 aacactagcg cgtaaggaac taactatgga agtcttggac tgttcggcta ttttattgtc
    14101 tttgtttatg aaccaatcca agacagctag caatatcatg tttatgcttg atttggggaa
    14161 tcatttagat cagtggtcct tgaaaaaaac tgcaacagat ttagaacaga gtcttcttgc
    14221 aaaagagagc gatgtattcc tagtacaggg cgatacggtt gttagtataa agagttccga
    14281 tgttcaaata ggagatgtct tgatcttatc tcaaggaaat gaaattctgt ttgatgggca
    14341 agtagtttca ggtttaggta tggtcaacga aagttccttg acaggagaga gttttccagt
    14401 tgaaaaaaga gagtctgatt tggtttgtgc aaatacagta ttagaaactg gagagttacg
    14461 cattcgtgta acagataatc agatgaacag ccgtatttta cagctgattg agttgatgaa
    14521 gaaatctgaa gaaaacaaga aaacgaaaca acgctatttc atcaagatgg cggataaagt
    14581 cgtcaaatat aatttcttgg gggctgggct gacttaccta ttgacaggtt ctttttctaa
    14641 ggctatttct ttcctattgg tcgatttctc ctgcgctttg aaaatctcta ctcctgtagc
    14701 ttatttgaca gttatcaagg aggggttgaa ccgtgaaatg gtgattaagg atggagatgt
    14761 tctggagaaa tatctggaag ttgatacttt cttgtttgat aagacaggaa caatcacaac
    14821 tagttatcct atagttgaaa aggtgttacc ttttggagac tatagtgagg aagatattct
    14881 cagaatcagt gcctgtcttg aggaacacat ttatcatcct attgctaatg ccatcgtcaa
    14941 gcaagctgag atagagggaa ttgaacatga ggaaatgcat gggaaactcc aatatatcgc
    15001 aagcaagggg atcaaatctc atatagatgg ccaaccagtt cttattggga attatgtctt
    15061 gatgcaggat gagcagattc atatcagttc agaacaaaat gctttaattg aagagtacaa
    15121 gagtcactac aatctcttat ttttggctta tcaaaatgaa ttgattggaa tgttctgcat
    15181 tcatactcct ttgagaaaag aagcaaaaac agccttggat aaacttaagg cacaggggaa
    15241 aaaattgatt ctggcaacag gagacacctt gattaggaca gaggaattag tcaaagattt
    15301 gccctttgat caggtctata cagacttgaa acctgatggg aaatttgagt tagtagagaa
    15361 actgcagaaa gcaggtcaca ctattttgat ggttggagat ggattgaatg actcagcggc
    15421 tttaactcta tcagatatcg gtgtggtgat gaatgagagt gcagatattt ctaagcagat
    15481 gagtgatatc ttattgttag ataatcgttt ggatttcttc caagagttgg attcgttatc
    15541 atcatctttg caaacactca tcaagaaaaa tattcaagat accgttgtcg taaatagtag
    15601 tttgattggc tttggcttat ttaattggtt cagtccttca aatctctcta tcttacataa
    15661 tctaacaacc ttgcgcattg tcttgcgtag cttgtctatt aaaaatagat agatgagagt
    15721 tattaacagc aaaaaggagt tacctttctc gaggttaact cctttgttta tagataaatg
    15781 ttgaatagtt tagtaagtca atacaaagta ttttttcttc ccacgacgga taacagtcag
    15841 ttcattttct aacttatcag cgtcactcaa gacatagtca aggtcttgga tgcggtcgcc
    15901 gtttacgtag atggctccgt tttggacgtc ttcacgggct tggcgttttg agttaactat
    15961 accagatgag acgagcagtt ccacgatatt gttatgttcg tctgcctgta cttggtagtt
    16021 tggcacacca cgaagtcctt gtttgagctc tttgacagaa aggtttttga tgtttcctgc
    16081 aaagagttgc tcagtgatgt taagtgcttc tttgtaggct tcttctccgt gaacaagtgt
    16141 aacaacttca cgagccaaga ctttttgagc caagcgttcg tgtggcgctg cttcaaattg
    16201 tttacgaata tcttcaatct catcaagtga caagaaagta aagattttca agaagcgaac
    16261 agcgtcagcg tccatcacgt tcatccagaa ttggtacatt tcgtatggag aagtcttttc
    16321 gggattgagc cagacggcat ttccttctga tttaccaaat ttcttaccag ttgcatctgt
    16381 gattagtgga acagtgataa cgtgaccagt cttgtccgcc ttacgacgaa gcaattcggt
    16441 accagctgtc atatttcccc actggtcaga accaccgatt tgaagagtga cattatggtc
    16501 ttggttaagg acgaagaagt cgtacccttg catgatttgg taagcgaact cagtgtaaga
    16561 aattcctgtt tcgatccgtt ttttaacaga ttccttactc atcatgtagt tgaccgtgaa
    16621 gtattttcca atatcacgga ggaagtcaat gaagctgatg ctgccaaacc agtcgtagtt
    16681 gttgaccatg acagccttgt tttcgccatt ttcaaagtca agaaaacgag aaagttgtcc
    16741 ttggatagac ttgacccagc catctactgt gtcttttgtt tggagactac gttcagcatc
    16801 tttgaaggac ggatctccga tgagacctgt agcaccgcca acgagcgcat aaggtttgtg
    16861 acctgctagt tgcaagcgac gacttgtcaa gattgcgaca aggtggccta ggtgaaggct
    16921 gtcagcagtt ggatcgtagc cagtataata agaaacttga ccttcttcta gggctttacg
    16981 caaagcttct tcatcagtcg tttgaaatat caaaccacgc tcttttagct catcaaaaat
    17041 gtgcatgtgt cttttctcct ttttaaaatt attgtttcta cctattgtat cacaaacttg
    17101 ggcaatagcc tagcagaata gggaagaaag tggctatttt attgaaaatt tcccttttgt
    17161 ggtataatag atagagtgag gaaatccatg caaaatcaat taaatgaatt aaaacgaaaa
    17221 atgctggaat ttttccagca aaaacaaaaa aataaaaaat cagctagacc tggcaagaaa
    17281 ggttcaagta ccaaaaaatc taaaacctta gataagtcag ccattttccc agctatttta
    17341 ctgagtataa aagccttatt taacttactc tttgtactcg gttttctagg aggaatgttg
    17401 ggagctggga ttgctttggg gtacggagtg gccttatttg acaaggttcg ggtgcctcag
    17461 acagaagaat tggtgaatca ggtcaaggac atctcttcta tttcagagat tacctattcg
    17521 gacgggacgg tgattgcttc catagagagt gatttgttgc gcacttctat ctcatctgag
    17581 caaatttcgg aaaatctgaa gaaggctatc attgcgacag aagatgaaca ctttaaagaa
    17641 cataagggtg tagtacccaa ggcggtgatt cgtgcgacct tggggaaatt tgtaggtttg
    17701 ggttcctcta gtgggggttc aaccttgacc cagcaactaa ttaaacagca ggtggttggg
    17761 gatgcgccga ccttggctcg taaggcggca gagattgtgg atgctcttgc cttggaacgc
    17821 gccatgaata aagatgagat tttaacgacc tatctcaatg tggctccctt tggccgaaat
    17881 aataagggac agaatattgc aggggctcgg caagcagctg agggaatttt cggtgtagat
    17941 gccagtcagt tgactgttcc tcaagcagca tttttagcag gacttccaca gagtcccatt
    18001 acttactctc cttatgaaaa tactggggag ttgaagagtg atgaagacct agaaattggc
    18061 ttaagacggg ctaaggcagt tctttacagt atgtatcgta caggtgcatt aagcaaagac
    18121 gagtattctc agtacaagga ttatgacctt aaacaggact ttttaccatc gggcactgtt
    18181 acaggaattt cacgagacta tttatacttt acaactttgg cagaagctca agaacgtatg
    18241 tatgactatc tagctcagag agacaatgtc tccgctaagg agttgaaaaa tgaggcaact
    18301 cagaagtttt atcgagattt ggcagccaag gaaattgaaa atggtggtta taagattact
    18361 actaccatag atcagaaaat tcattctgcc atgcaaagtg cggttgctga ttatggctat
    18421 cttttagacg atggaacagg tcgtgtagaa gtagggaatg tcttgatgga caaccaaaca
    18481 ggtgctattc taggctttgt aggtggtcgt aattatcaag aaaatcaaaa taatcatgcc
    18541 tttgatacca aacgttcgcc agcttctact accaagccct tgctggccta cggtattgct
    18601 attgatcagg gcttgatggg aagtgaaacg attctatcta actatccaac aaactttgct
    18661 aatggcaatc cgattatgta tgctaatagc aagggaacag gaatgatgac cttgggagaa
    18721 gctctgaact attcatggaa tatccctgct tactggacct atcgtatgct ccgtgaaaag
    18781 ggtgttgatg tcaagggtta tatggaaaag atgggttacg agattcctga gtacggtatt
    18841 gagagcttgc caatgggtgg tggtattgaa gtcacagttg cccagcatac caatggctat
    18901 cagaccttag ctaataatgg agtttatcat cagaagcatg tgatttcaaa gattgaagca
    18961 gcagatggta gagtggtgta tgagtatcag gataaaccgg ttcaagtcta ttcaaaagct
    19021 actgcgacga ttatgcaggg attgctacga gaagttctat cctctcgtgt gacaacaacc
    19081 ttcaagtcta acctgacttc tttaaatcct actctggcta atgcagattg gattgggaag
    19141 actggtacaa ccaaccaaga cgaaaatatg tggctcatgc tttcgacacc tagattaacc
    19201 ctaggtggct ggattgggca tgatgataat cattcattgt cacgtagagc aggttattct
    19261 aataactcta attacatggc tcatctagta aatgcgattc agcaagcttc cccaagcatt
    19321 tgggggaacg agcgctttgc tttagatcct agtgtagtga aatcggaagt cttgaaatca
    19381 acaggtcaaa aaccagggaa ggtttctgtt gaaggaaaag aagtagaggt cacaggttcg
    19441 actgttacca gctattgggc taataagtca ggagcgccag cgacaagtta tcgctttgct
    19501 attggtggaa gtgatgcgga ttatcagaat gcttggtcta gtattgtggg gagtctacca
    19561 actccatcca gctccagcag ttcaagtagt agttctagcg atagcagtaa ctcaagtact
    19621 acacgacctt cttcaagggc gagacgataa ttctctaaat gaagtggcca atcaatggat
    19681 tgccactttt ttcctttcgt gttacaataa gggtatgaat cagtatcaga aaaagattgt
    19741 taacggaaaa atttattcgc tcctatccgg cttaatatgg ggaatctgtg gaattttagg
    19801 agagtacttc tttactcatt atcaggtgtc ttcgggctgg attacctcta tgcgtttgac
    19861 actggcaggg agtcttgtac tcatttggtc tgcaatacaa ttaaaatcgc aagtgctaga
    19921 tatttggcga gacaagaaaa attacctgcc ctttttagcc tatgctattt tggggatttt
    19981 ttcagttcag tattttttct atctctgtgt agaatactca aatgctacga cagcaactat
    20041 tttacagttt attagccctg tctttatcct cttttataat cgcttggttt atcaaaaacg
    20101 agcgtcaaaa agcgctgttt tctatgtttt ggttgccatg ctgggtgttt gcttgatggc
    20161 gacaaaggga gatctctctc agttatccat gacgccgcta gctcttataa caggtttgct
    20221 gagtgccatg ggtgttatgt ttaatgttat cttgccccaa ccttttgcta agcgttatgg
    20281 ttttgttcct acggttgggt gggggatgat tttggcaggt ttgtttagca atgtcctctc
    20341 gccggtttat cagctttcct ttactcttga tatttggagt atcttgattt gcctcattat
    20401 cgctttcttt ggaacggctt ttgctttttt catttccatg aaggctgtgt ccttggtttc
    20461 tcctttggtg gtttccgtta tcagtgccag tgaacctctc tcttctgctc tcttgagtgt
    20521 tttgttctta ggattagtag tggattggtc cctccttcta gctatagcct tgattatttt
    20581 acccatgata tttttgtcta tagaagaagc gaaagaaagt agataaaaag tcttttctta
    20641 attctaaaag tgtgctatac tagaatagtc aataaaacac ggggagatag ttgtgaagag
    20701 tgtttttagg ttgtatcggt aggggcttgc ttttaccgac agcacgtttt atctcacaac
    20761 cctaaaaaat catacctaaa aacagacaaa aaggtttcaa atttgaggcc ttttttggta
    20821 gaataggtat cattataacg aaccaggagg cacctatgac tgctacaaaa atgaacgctc
    20881 aagaaattat ccaatttatc gccaatgctg aaaagaaaac cagtgtcaaa gtaacctttg
    20941 aggggcaact cgcaactgct gtgcctagct ctgttgtcaa actaggaaat gtcctattcg
    21001 gagactggaa ggacgtggct ccgcttcttg aaggtttggt agaaaatcaa gattatgttg
    21061 tcgagcaaga tgctcgtaat tctgcagttc ctttgctaga taagcgtgct atcaacgctc
    21121 gtatcgagcc aggtgctatt atccgtgacc aggtggaaat tggtgacaat gctgttatca
    21181 tgatgggagc tgttatcaat atcggtgctg aaatcggtgc tggaaccatg attgacatgg
    21241 gtgccatcct tggtggccgt gctatcgttg gaaaaaatag ccacgttggt gcaggtgcag
    21301 ttttggcagg tgtgattgag ccagctagtg ctgaaccagt ccgtgtcgga gacaatgttc
    21361 ttatcggtgc taatgcagtg gttatcgaag gagtccaaat cggtagtggt tcagttgtcg
    21421 ctgcaggagc tatcgttacc caagatgtcc cagaaaacgt ggtagtagca ggtgttccag
    21481 ctcgtatcat caaagaaatt gatgcccaaa cccaacaaaa aacagcgcta gaggatgcgc
    21541 ttcgtacctt gtaattgtaa aagtaaaaaa gaggcggaac cctttttcca gcctctttct
    21601 gctatatcgg aggacagata gatgttagat ttgattcaga ctagacgagc tttacaccag
    21661 attccagaga ttggcttgga ggagttcaag actcaggctt atttgctgga tgtgattgag
    21721 aaattgacta cgggcaagga ttttgttcaa attcgtactt ggcggacagg gattttggtc
    21781 tacctgcagg gaagtcagcc ggagcgaacc attggttggc ggacagatat tgatggcctg
    21841 cctatcgtcg aacaaacagg tctacctttt gcttctcaac accaaggtcg catgcatgcc
    21901 tgtggccatg attttcatat gaccattgcc ttaggctgtc ttgagcgcgc ccttgaggag
    21961 caacccaaga ataatctgct ctttctattt cagcctgctg aagaaaatga agctggtggt
    22021 atgctcatgt atgaggatgg tgcttttgga gattggttgc caaaccaatt ctatggtctc
    22081 catgttcgtc cagatttgaa agtcggccag attgcgacta atactcatac actctttgca
    22141 ggaacttgcg aggtgaagat ccgtttcaaa ggcaaaggtg gccacgcagc ttttcctcat
    22201 gaagccaatg acgccttggt ggcggctagt tactttgtga cccaagtgca gtcagttgtt
    22261 agccgcaatg tcaacccaat cgagggagca gtggtgacct tcggcgtttt tcaagctgga
    22321 accaccaaca atgtcatcac agacacagct tttttacatg gaactattcg tgccttgaca
    22381 caggacatga gtctcttggt gcaaaagagg gtaaaaacag ttgcagaagg ggttgcagct
    22441 gcctttgata tggaagtcga agtggaactc aaacaaggtg gatacctacc tgttgagaac
    22501 aatccagcct tggcgcgtga actgatggac ttctttgacg aaaaagacgg aatcgagttg
    22561 attgatatcg aacctgctat gacaggcgag gactttggtt atctcctttc aaaggttgat
    22621 ggcgtgatgt tttggctagg tatcgatagt ccctacgctc ttcatcaccc tcaaatgagt
    22681 cctaaggaag aagtcttagc tattggggtg gctgcggtgt ctagtttcct gaaaaagaag
    22741 gcagcagaat agagggcttg tctatgaaat cggaattacg caagcaagtc ttgcaaggaa
    22801 tgaaggctat atctcaagaa caaaaacagt ttatagatca aactttaacc gagcggcttt
    22861 tacaccatcc cttctatcaa gaagccaagg tcatcgcaac ctacctctct ttttctcatg
    22921 agtttcaaac gcgggaactg attgagcagg cgctgaagga cggcaagaag gttttaatac
    22981 ccaaaactta tcccaagggg cgcatggact ttgtagtcta tgatctgcag cagttggtaa
    23041 aaactgcctt tgccttactg gagccacagg gagatttgga agtggtggat gtatctcaga
    23101 ttgatttgat tcatgttcct ggcctggctt ttacgacgga tggatatcgg attggatatg
    23161 gtggaggtta ttatgaccgc tatctggaac atttttctgg tcatactttg agtacggttc
    23221 atccttgtca aattcaggac tttatacctg aaaaccatga tattcctgtt caggaggtat
    23281 taattgatga aggaaatctt tgatagacgt taccctgtga cgagtttctt cctcttagtg
    23341 acggccttgg tatttttact aatgttggtc actgcaggcg ggaactttga cagggcagat
    23401 acattatttc gatttggagc catgtatggg ccagctattc gcctctttcc cgagcaggtt
    23461 tggcgtctct tgtctgccat ttttgttcat attgggtggg aacatttcat tgttaatatg
    23521 ctttcacttt attatcttgg aaggcaggta gaggagattt tcggttctaa gcagtttttc
    23581 tttctctatc ttttatcagg aatgatgggc aatctctttg tttttgtatt tagtcctaaa
    23641 tccttagcag caggcgcctc tacctctctt tatgggctat ttgccgcgat tatcattctt
    23701 cgctatgcaa cgcgtaatcc ttatatccag cagttgggcc aatcctatat gacacttttt
    23761 gtggttaaca ttattggaag tgttctgatt ccagggatca gcctagcagg ccatatcggt
    23821 ggagcagttg gtggcgcatt tctagcagtt atctttccag ttagaggaga aaaacggctg
    23881 tataacacca gccagagatt aggagcggta gtcttgttcg taggactcgc cattttgctt
    23941 ttctacaagg gaatgggaat gtgacgaagt tgaaagaaaa tttgtgtaat gaaaaaagat
    24001 aaggcatttt ttgaacctta tctttttatt ttattccttc tcagtcaatt cttttccaag
    24061 ttggatgagg taattcttca aatcatcttt gacttgtgga tgtttgaggg cgtagtcaat
    24121 agatgttttc ataaagccaa acttatcccc aacgtcgtaa cgagctcctg taaatttacg
    24181 ggcaaaaaca cgctgtgttt tattaagagt atcgattgca tcagtaagtt ggatttcatt
    24241 tccagcacca ggagcttgct tttcgagaat ctcaaaaatt tctggtgtga gtagatagcg
    24301 accgatgatt gccaaatcac ttggagtctc ctcgggagct ggtttttcaa caaaggtttc
    24361 aacactgtaa agaccatctt ttccttcgtc ttgaggagca atgactccat atgatgaaac
    24421 gtcttcgtgt ggtacgggca tgacagcaat ggttgatgcg tgtgtctttt cgtaatcatt
    24481 catcagttgt tttgtcaaag gaacggcctt ctcgtctgtg atgtccatca agtcatcacc
    24541 cagcataaca acaaaaggtt catttcctac aaaagctttg gcttgtaaga cagcgtctcc
    24601 aagaccacga gggtgagttt ggcggatgaa atgaaggcgc atgccagttg cttcatctac
    24661 caattttaac aaatccgttt tgcctttttc cttaagattg tattcaagct caaagtttga
    24721 atcaaagtgg tcctcaatag aacgttttga tttaccagtg acaactagaa tatcttcaat
    24781 acctgatttg agagcctctt ccacgataaa ctggatagtt ggtttgtcta cgattggcaa
    24841 catttctttg gcaagggcct tggttgctgg taaaaatcga gttcctagtc cagcagcagg
    24901 gataactgcc tttctaactt ttgatgtcat aaaaatcctt tctatagagg gttaagacca
    24961 ctcattttct gctttaaatt cattgttcat gatgtcataa atggcatctt tgatattggt
    25021 tccgtgataa ataacttggt aaatagcctg tgtaatgggc atatagactc caagttcttg
    25081 ggctagttca taggctgctc gagtcgttga aattccttcg attaccatgc ccatattagc
    25141 ttctatatca gctagggatt ctcctcgtcc gagagcatct ccagctctcc agttacgaga
    25201 gtggatggaa gttcccgtta cgatcaaatc tcccacacca gataagccgc tataggtcaa
    25261 tggactggcc ccgagtgcta cccctaggcg ggtgatttct gctaaacctc gagcgatgat
    25321 ggctgcctta gcattatcac caaatccaag accatgtaaa gctccagcac cgacagcaat
    25381 aatattttta agagcaccag cagtttcaac cccgataaca tccgtattgg tataaagtcg
    25441 gaagtagtga ttactaaata gctcctgaac gtattgagct gtttgtaaat ctttagaagc
    25501 agcagttatt aaagttaggt cacgcacaat ggtctcttct gcatgactag gccctgaaac
    25561 agcgacgata tcactacgga gatgttcagg aatttcttct tcaagaatgg ttgataatcg
    25621 tttatggcta tcaggttcta atccctttga tgcgtgcatg atgataacct tatggtccaa
    25681 ggtttgtgca acttgctggg caacaagtcg tgtcactttt gttgggacaa caaacaaaat
    25741 cgcatccaca tttttcaatg tttctgctaa gtcggtgtag gcaatgatat tttcgtctag
    25801 aacgacatct ttaaagtagt gcttattagt atggtgtgta ttaatttcat tgatttgctc
    25861 gggaagattt ccccaaatac gtacctcgtg tccattgtca tttaagactt gtgaaagggc
    25921 ggttccccaa gaaccaggcc ccaagacggc gacggtttgt ttttccatga tttcctcctt
    25981 gatagatttc tttctcttat tctatcatat tctaggggat tttgcacttg cattactggg
    26041 gtatggtgga aaaatacaca aagaccgaga tgaagggata aactcttagt ctttagttaa
    26101 agtgagaaga aatctgatag atagtttgat tcagtatatg cttataatag aggtaaacaa
    26161 ctcaggaagt tcttgtaggt tgcgagagtt tggcgaaaaa attaaaagat tacgtttggc
    26221 taaaaaaatc agtcgttcag aattttgtgg tgatgagtct gaattaagta tccgtcaatt
    26281 aattagaatt gaaaatggag aatccagacc aatactaaca aagttaaaat atattgctga
    26341 acgtttggag gttgaagatt acaagttgat gccaagttat atagagttgg ataaggaata
    26401 cctagaattg aagtatttct tgatgaggac tcctacatac gaagatgaaa ctatcaccca
    26461 aaagaaagag agtgtttttg ataagatttt tgaagagtat tatgataggc tacctgagga
    26521 agaaagattt atcatcccaa attattcata tctggcacta acgaactaca cagttcaaaa
    26581 attaccagaa aagctagttg aaatactgtc cttctggtga ttttgcttaa tttctgatgt
    26641 tcgagacatg attgaggaga tttgtcttga ttttttccta aaaaagggca gactcctccc
    26701 ttggtttgat gctcgatttt taaaataagg tgacttattc tgttaggcat gttttcccct
    26761 gccctctagc tctatatgga acagggagta tcagatttat ctggcagatt gtatcaaata
    26821 aggcttgaaa ctgttttgaa taggcatata gacttgagaa tttgagaata tgtcgtctag
    26881 cagtagagac atattttccg gcaatatgaa ggaagagacg tcgaaaacgc ttgatagtca
    26941 aggcctttac ttcatcacca gctagctgct ttaaaaagag gtagagatta taagccagac
    27001 agcccatcat catacgtact tcattcttaa tcatggtcga actatctgtc ttatccccaa
    27061 agaatcctgc tttcctttct ttgataaagt tttcagcatt ccctcgttca cgatagaatt
    27121 gaaacagctc ctcactatct acactgctta aattggtcaa atgaactttt ttacaaccat
    27181 aaaaaagagc acttaatcgt actcttctct tttaaggatt agttgaatta attcaaatcc
    27241 actagttctc ctgtttctag gtagactagg cgttcacaaa tgttagcaat gtaatcagcg
    27301 aagcgttcca gatgccctat gatataaagg tattgagttc cattgggaat tgaggtttct
    27361 tggtctttca taagtccaat gatttccttt gataaggcat aataatattg gtcaatctgt
    27421 tcatcttttt gagcaatact aatagctttt gaggcttggt gcaaaggaaa ggcaaccaat
    27481 aaatcggcta gcatgctgag ggataattta cccatttggt gtaactgttc ttcgtcaggg
    27541 gctagttgat tttcttttag ttgcaaaaca gctttggcaa tgcctgccat atggtctccc
    27601 atacgttcaa ggtctgaaca agaagacatg atgctaatca caaatcgaag gtcagacact
    27661 tgtggctgct gcaaggctaa caaacgggca caggtcaatt cgatagcgct ttgaccttgg
    27721 ttgatagcat gatccttatt gataattagc tctgccatct ccttgtcttt ggaggctaag
    27781 gccagtaagg cttttgaagc tgtttcaagg acaagttgcc ctagtcctaa aaaggattgt
    27841 tctaattcat gcaattctaa gtcaaattga tttctcatag gtttttcctt ccttatccga
    27901 accgtcctga aatatagtct tctgtgcgct gatcttttgg attggtaaac acgtcaacgg
    27961 tatctccaaa ttcgcaaatt tctcctgtta agaaaaaagc agttttatct gaaatacgtg
    28021 aagcttgttg catgttatgg gtaacaatga taatcgtata atcctttttt agttgctgaa
    28081 tgaggtcttc aatttttaaa gtggagatag ggtctaaggc tgaagtcggc tcatccatta
    28141 acagaatatc aggttctact gctaaagctc gcgcaatgca aaggcgttgc tgctgaccgc
    28201 cagataagga catggcactc tttttaagat cgtctttgac ttcttcccaa atggctgccc
    28261 cttttaaaga tttctccact aaggcatcta attgtttttt gtctcgaata ccatgtgtcc
    28321 ttggaccata agccacgtta tcatagatag acatggcaaa gggattaggc tgttgaaaaa
    28381 ccatccctac acgcttgcgt agctgattaa ggttgaattt gctactataa atatcttgct
    28441 catctaagag gacttggcct tcaatatggc aagaaggaac caaatcgttc atccgattaa
    28501 gggtttttag aaaagttgat ttgccacaac cagatgggcc tatcaaggca gtaatctgtc
    28561 tttctggtaa ttgaatcgaa atatttttta aggcttgaaa atccccgtaa aataagtcta
    28621 ggtgtctaac tgaaaatgtt cccatactag gaagctcctt tcacaagttt tcgagataat
    28681 aagcttgata gagtatttat cattaaaaca gtaataatca aaatcacacc ggtagcatag
    28741 gcttcattga catgtagccc ctcacttgac agcatataca tatgcagggc tagagaacga
    28801 cctgaagaca tgagactact tggcgtattg gtagaggtac ctaatgtata catgagggca
    28861 gctgtctcac caacgatacg gccaatagct agtatcactc cagctaaaat acctggcatg
    28921 gcaactggta gaacaattct aaaaacagtc cgtaacttac ctgccccaag tccataactt
    28981 gcttgacgca tgctatcact aacagataaa agggcttctt ctgttgagcg aataatgact
    29041 ggcaacacca tgatgactga ggttaagatt cctgataaca gagagtattg aaaacctaag
    29101 aagactacaa agaagagcat gccaaacaga ccaaaaacaa tggaaggaat cccagacaag
    29161 gtatctgagg ccaatcgcat gattttaaca caaagggaat ctttttttgt atattccaca
    29221 agataaaaac cagcaaaaat ccctatgggc aaggctaaaa gaagagcacc aaagaccaga
    29281 ataacggtgg aaataatcgc tggcataagg gaaatgttct cagaagtata agtccaagaa
    29341 aagagggata gacttagatg aggtaagcct ttgatgagga taaaaccaat gattaaaaag
    29401 agagagccaa aggttaaagc tgaaaaacaa taaacgagaa gttttagcag gtatttactc
    29461 ataagatgat tttcctttca agtaggcaaa gtaggcatta atcaagagaa taaggaaaaa
    29521 gagaactgct gaggttgcaa taagggcttc cctatgctga cctgatgcgt aagccatttc
    29581 cagaacaata ttggttgtta aggttctggt tcctgaaaag agtccacttg gaataatcgg
    29641 ctggttgcct gccaccaaaa taactgccat ggtttcacct actgcgcgac cgattcctaa
    29701 aataactgct gataaaatac cagatctcgc agctggcaag atgacactaa aaatactccg
    29761 ttcatgacta gctcctagag ccaagctacc agaataatac gttttgggaa ctgttcggat
    29821 agcagattct gacaaactga taatggttgg caaaatcatt attcctaata gtaacgaagc
    29881 ggttaggaca ctcatgccat ttcctaaaaa ggttctaatc caaggcacca ataattgtag
    29941 gccgaaaaaa ccataaacaa tagatggaat ggccgccatc aagttgatag ctgattttaa
    30001 gaagccatag acgggctttg gacaataata aaccataaac accgatgtca agatgcctgt
    30061 tggcacccca atcacaatcg ctcctaaggt aattaataag gaaccaacga tcattggtaa
    30121 aataccatag cttgccggaa tgttcgttgg cgaccaatca ctgcctaata aaaaacgggc
    30181 aaagccgtag ttagccatga aaggtaagcc attactaaaa ataaagaaac agattagcaa
    30241 aatagctaca acagctactg ttgcactcat gaaaaaaatt gccctaaaaa ctgcttcttt
    30301 gaaggcttgt tttatcacat cttgtccttt ctagtgaaga aagtaaggga gatacgacac
    30361 ctccctactt gccttcttta tcttattgta cgatgaaacg tctgcatctc tttagagatt
    30421 tatggagcaa acattttatt taatcttgtc ccaggtggtt aatttgccac taaaaacgtc
    30481 tgcaagttca gccatactga cttggcttgc cttattgtca ttattgacca caacagcaat
    30541 accgtctaaa gcaatagcat catgggtgag actcttacct tcttcaggag ttaattccct
    30601 agaaaccata ccaatatcag cggttttctc cttaacagcg gtaatacctg ctgaagatcc
    30661 attagaggta atatcaatcg taacttctgg attttctttt ttataagctt ctgctaattt
    30721 ttccattaaa gaagatactg aagtggaacc tacaacagac aacttgcctg ataagtgttg
    30781 gcttgtatat tctgtggttt cggttttagc ttcaataaat ttattatctg tgaccacttg
    30841 ttgaccttgt ttggagtgga taaagctgat aaaatcttga cctagcttgg aaagattaga
    30901 agaccaaaca atgttgaagg gacgttgaag agggtattca ccatctaaaa ctgtgtctcg
    30961 actagccttg acaccatcaa tctctaaagc cttgacagat ttcgttaaag atcccaagga
    31021 gatgtagccg atagcattag cattcccttg aactgctgag agaacacctt ctgtactatt
    31081 ttgaatcaca gctgttttgg cagtgttgtc aattttttta tcaccgtctt ttttgagaat
    31141 ccctgtgatt tctgtgaagg caccccgtgt tccagagcca ttttctcgtg aaatcacctc
    31201 aatcgttcct gaagctgact gtttggaagc agctgactga ttgccacagg caacaagccc
    31261 aaatcctgat aagccaatgg ctgcaagagt aagcattttt ttgaatttca taataatcac
    31321 ctttatctct atgtattttt cttgtgtagg cttactacat ttatagtcta acaagtcttt
    31381 gtaaaggttt atccctgatt catgtaaaga ttgtgtaaag aatcaaaaaa agccactttt
    31441 gaaaaatggc tgctcctaaa aatagcttta aaaattatta gtcctgtgcg aaagattggt
    31501 taggaagaaa aatcgtgaag caactgcctc tgccaagctg actcgtcacc gtgacttggc
    31561 cacctaataa ttgactgagt tctttgacaa tggcaaggcc aagaccagtg ccaccagttt
    31621 gtctgcttcg acctttatta actcggtaaa aacgttcaaa aatacgatcc tgctctaatt
    31681 gactaatacc aatccctgta tctgatacag aaatcttaat gccttcgttc accttttggg
    31741 tcttgacctc aatttttccc ccttgttcag tgtaacggat ggcattggat aaaagattga
    31801 gtaagatttg ggaaagtaat tgactatctg atacgagggt gacatcatct ggcacctgca
    31861 cctttagctg taaatccttc ttcttgagct gaggttgcaa gctttgagtc aaatcctgta
    31921 caaattctgc caaagaaagg gtcgtccatt gtataggcat ttgttgagcc ttagataagg
    31981 taagaagatg ctcaacaata tgctcaagac gcaaactttc tttgtaaata atgtctagaa
    32041 agtcatcctt gagcgcttct tcttcagctg acatcccctt aatggtttca gcaaagccct
    32101 taatcgaagt aactggtgtc ctcaattcat gggaggcatt tgagacaaag gctaaattta
    32161 acttttcata agttctaatc gttgttaaat catatagcaa gacgagcaca gcttccacag
    32221 attgggtggg gctaaaaacg ggaactgctg tcacttctaa aatcaagtca ccctcatgaa
    32281 acccacttac ttcttgtttt aaccttgttt tttgatcaaa ggcttggtga actaaattcc
    32341 gaatatccat ccgtttgagg tcatcaagtg aacttatgtc gccgtccaca tcgggaaaat
    32401 aatgaggcag agagcgactg gataataaca tctgaccttg agcggaaact aaaaacgtcc
    32461 ccatggttag gtgcgacaga agaacctcca ttgtttcggc tagatccttg tattgctgat
    32521 cctgttggga gactttggtt tttaggccag acacatactg agccaaagac tttaagtctt
    32581 cttgcccttt ttctaaaaag tattcactac tggtcaagag aggttggtgc aaggtctcaa
    32641 aagcaacttc ccatttccaa aggcaaaaga gccagtagcc acctagtccc aaagaaaggg
    32701 ctagaagaaa gagaccgatg cctttactga tccaagttaa tgccatccct gcaatcagaa
    32761 tgaggctaac acttagattg actagccaaa attgaaggta gcgtttcatc tataactcct
    32821 tgaacttata accataaccc cgaatggttc gaataaattg aggggcttta ggattgtctt
    32881 caattttttc cctcaactta ccaatatgaa cgtccaccaa acgtgtttcc tgcccaaagt
    32941 cataccccca gatacgttcc aaaagacgct ctctagtcag tgtcatgttg ggatgtttca
    33001 taagatagag caagagttca aattcttttg gggtcaaact cagtaactta ttcgccttgt
    33061 agacttcatg acgctcaggg tatactttca aggtcccaaa tagccaagaa tcgtcagcga
    33121 tattatctga atcatctcct tcttgttctc ctttagttcg cctgaggaca gccttgacac
    33181 gcgccagcaa ttctctaggg ctaaaaggct tggtcaggta gtcatcagcc cctaattcca
    33241 aggccaaaac cttatcaaat tcatcacttt tcgcagaaac catcataatt ggagttttga
    33301 cgcctttggc tctcagccgc ttacaaactt ccatgccatc taattgtggt aacatgatat
    33361 caagcaagat aaaatcaaag ggttctgttt ctgccaaagc taaggccttc cgtccatttg
    33421 tcaccaattg agtagaaaag ccttccttac ttaaatggta gtcaagcaat ttcagaatgt
    33481 gttcttcatc atccactaat aagacttgtt ttgtcatcta ttatctccta ttggtaacat
    33541 tataacacaa ttatcagaaa tcctaacatt gctaaatcag attaaatttg cctatcaaga
    33601 ctagtatctg gtcaaacgct caatcatctc cttgtgctct ggataggtcg ccagtagatc
    33661 taccctttca aataattcaa aatcctcaaa ttcaaaacca ggaacaacaa gacaagaaac
    33721 cagagcatca tccttatcaa ctgttgatcc ccaaatagtg cccttaggaa cacagtagtg
    33781 aagttgttgc cctttggata tgtccaggcc taaagtgact gcttcgtagt gaccatctgc
    33841 tgtaatcatg tgaacagtaa gtggggatcc tgcatgaaaa taccagattt catctgctgt
    33901 caatcggtga aaatgtgaag gattcgtttc ttctaataag aaataaatac tggtataaag
    33961 cgcccttccc ttaccagcaa ggtttatagt gtctgaagct ttttttgttt gtctaaaata
    34021 gccaccttca atatggggag ctaactctag agttcttatc aagtcttctt tatccgtcgg
    34081 agccaatggg ttgaagtaac tcttgttcaa agtggtttta cgattttaag aactcctctc
    34141 agttctgagg acacggtaat gattgatgcg acggaagtac aaatcaatcg ccctaaaaaa
    34201 agaattagcg aattattctg gtaaaaaaaa tgccacgcta tgaaggctca agcgattgtc
    34261 acaagtcaag ggagaattgt ttctttggat atcgctgtga actattgtca tgatatgaag
    34321 ttgttcaaaa tgagtcgcag aaatatcgga caagctggta aaatcttggc tgacaatggt
    34381 tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc cagcaaactc
    34441 aagccactaa cagttgaaga taaagcctat aaccatgcgc tatccaagga gagaagcaag
    34501 gttgagaaca tctttgccaa agtaaaaacg tttaaaatga tttcaacaac ctatcgaaat
    34561 catcgtaaac acttcggatt acgaatgaat ttgattgctg gcattatcaa tcatgaacta
    34621 ggattctagt tttgcaggaa gtctattatt tggttaggtg aattagtgaa gcgtttaggc
    34681 aagtgtctct ggttacgacg tcatggactc taaatcgatt atatttaggg gtcatgacta
    34741 gtgaagcagt tagctagttc gcatataagc ggctagcgtc taacaattag gaactttagt
    34801 tccaataact ttaagattac gacgttttag gacataaatc gatcatattt atgtcctaaa
    34861 actagtgaag cgcctagcca aagtccgaat aggatttggc gttagttact tagattgctt
    34921 tgcaatcaag taactttggc gatttacatc ttctctggcg cttctactcc aagcaagcga
    34981 agggcttctt tgagaacgac tgcggttgcg tagctgaggg ctagacggct gtcgcgttct
    35041 gggctttcat ccaagatacg tgtatgtgca tagtatttgt taaaggattg agccaggcta
    35101 attgcaaatt tagcaatgat agaaggttca aagttatctg ccgcacggtt gataatacgt
    35161 gggaagtctt gaatgagttt aatgatttcc cagctttcag tatcattcaa gctatagttg
    35221 ccagctgttt ctggtttgaa atcggctttg cgtaagatag attggatacg agcgtaggca
    35281 tattgaacgt aaggtccagt ttcaccctcg aaggatacca tagcttctag gtcgaagtcg
    35341 tatccatttg tacggtcagt tttgaggtca tagaatttaa tggctccaac cccaacagca
    35401 tgtgctactt ggtctttgtt ttctagttca ggatttttag cctcgatttg gaccttggca
    35461 cggctaacag cctctgcaac agtaggctct agcaagatga cattcccttt acgagtagag
    35521 agcttcttcc cttcttttgt aaccagacca aaaggaacgt gggtaatgtc gtcactccaa
    35581 tcgtagccca tctcttgcaa gacagctttg agttgtttaa agtgggcaga ttgctcttga
    35641 ccaacgacgt agatagattt agcaaattgg tattcatttt tacggtagag ggctgcagcc
    35701 aagtcacgtg tgatatagag agttgcacca tcagacttct tgatgagagc tggatgttca
    35761 attccatatt tctcaagatt cacaacttgg gcaccttctg attcaagaag tagtcctttt
    35821 tcagaaagaa tgtctacaac tgcatccatc ttatcattgt agaaggcttc tccgttatag
    35881 ctgtcaaatt caaccttcaa ttcattgtaa aggcggttaa attccactaa actttcatcg
    35941 cggaaccatt gccaaagagc gagagcttcc tcatctccat tttcaagttt acggaaccat
    36001 tcgcgcgctt cttcatccaa gctagggtca ttttcagctt cagcgttgat gcggacatag
    36061 agtttaagga gttcatcgat tggatgagct tttacagctt cttcgtcgcc ccatttttta
    36121 taggcaacaa tcaacatccc aaattgttta ccccagtctc ccaaatggtt gaccttgacc
    36181 gtttgataac cgattttttg gaaaatatgt gacaagctat ctccgataac agttgaacgc
    36241 aggtggccaa tagaaaatgg tttagcgata ttcggactag acatgtcgat aacaacattt
    36301 tcttgtttac caatattttg gtcagcatag tgttcttttt cagtggtaac agcttgcaat
    36361 acttgagcag aaatggcaga tttatcaagg aaaaagttaa cgtaaggtcc tgttgcgaca
    36421 actttttcaa aggcttggct gttcattttt tcagccagtt cagccgcaat catttgtggt
    36481 gctttacgtt cgacttttgc aagagaaaaa gcagggaaag caatgtctcc catttctgag
    36541 tttttagggg tttccagtaa ctttaaaata gcctcttggt ccaggctatc aatgatgcta
    36601 gataattcgc tagcaatcaa ttcttttgta ttcattaaga gctccttttt ggacttttct
    36661 actattttat cacaatttta aagaaagaag aaaaaatttt tgaaatctcc tgtttttttg
    36721 gtataatatg gttataaata tagttataaa tatgcacgca agaggatttt atgagaaaaa
    36781 gagatcgtca tcagttaata aaaaaaatga ttactgagga gaaattaagt acacaaaaag
    36841 aaattcaaga tcggttggag gcgcacaatg tttgtgtgac gcagacaacc ttgtctcgtg
    36901 atttgcgcga aatcggcttg accaaggtca agaaaaatga tatggtgtat tatgtactag
    36961 taaatgagac agaaaagatt gatttggtgg aatttttgtc tcatcattta gaaggtgttg
    37021 caagagcaga gtttaccttg gtgcttcata ccaaattggg agaagcctct gttttggcaa
    37081 atattgtaga tgtaaacaag gatgaatgga ttttaggaac agttgctggt gccaatacct
    37141 tattggttat ttgtcgagat cagcacgttg ccaaactcat ggaagatcgt ttgctagatt
    37201 tgatgaaaga taagtaaggt cttgggagtt gctctcaaga cttatttttg aaaaggagag
    37261 acagaaaatg gcgatagaaa agctatcacc cggcatgcaa cagtatgtgg atattaaaaa
    37321 gcaatatcca gatgcttttt tgctctttcg gatgggtgat ttttatgaat tattttatga
    37381 ggatgcggtc aatgctgcgc agattctgga aatttcctta acgagtcgca acaagaatgc
    37441 cgacaatccg atccctatgg cgggtgttcc ctatcattct gcccaacagt atatcgatgt
    37501 cttgattgag cagggttata aggtggctat cgcagagcag atggaagatc ctaaacaagc
    37561 agttggggtt gttaaacgag aggttgttca ggtcattacg ccagggacag tggtcgatag
    37621 cagtaagccg gacagtcaga ataatttttt ggtttccata gaccgcgaag gcaatcaatt
    37681 tggcctagct tatatggatt tggtgacggg tgacttttat gtgacaggtc ttttggattt
    37741 cacgctggtt tgtggggaaa tccgtaacct caaggctcga gaagtggtgt tgggttatga
    37801 cttgtctgag gaagaagaac aaatcctcag ccgccagatg aatctggtac tctcttatga
    37861 aaaagaaagc tttgaagacc ttcatttatt ggatttgcga ttggcaacgg tggagcaaac
    37921 ggtatctagt aagctgctcc agtatgttca tcggactcag atgagggaat tgaaccacct
    37981 caaacctgtt atccgctacg aaattaagga tttcttgcag atggattatg cgaccaaggc
    38041 tagtctggat ttggttgaga atgctcgctc aggtaagaaa caaggcagtc ttttctggct
    38101 tttggatgaa accaaaacgg ctatggggat gcgtctcttg cgttcttgga ttcatcgccc
    38161 cttgattgat aaggaacgaa tcgtccaacg tcaagaagta gtgcaggtct ttctcgacca
    38221 tttctttgag cgtagtgact tgacagacag tctcaagggt gtttatgaca ttgagcgctt
    38281 ggctagtcgt gtttcttttg gcaaaaccaa tccaaaggat ctcttgcagt tggcgactac
    38341 cttgtctagt gtgccacgga ttcgtgcgat tttagaaggg atggagcaac ctactctagc
    38401 ctatctcatc gcacaactgg atgcaatccc tgagttggag agtttgatta gcgcagcgat
    38461 tgctcctgaa gctcctcatg tgattacaga tgggggaatt atccgaactg gatttgatga
    38521 gactttagac aagtatcgtt gcgttctcag agaagggact agctggattg ctgagattga
    38581 ggctaaggag cgagaaaact ctggtatcag cacgctcaag attgactaca ataaaaagga
    38641 tggctactat tttcatgtga ccaattcgca actgggaaat gtgccagccc actttttccg
    38701 caaggcgacg ctgaaaaact cagaacgctt tggaaccgaa gaattagccc gtatcgaggg
    38761 agatatgctt gaggcgcgtg agaagtcaac caacctcgaa tacgaaatat ttatgcgcat
    38821 tcgtgaagag gtcggcaagt acatccagcg tttacaagct ctagcccaag gaattgcgac
    38881 ggttgatgtc ttacagagtc tggcggttgt ggctgaaacc cagcatttga ttcgacctga
    38941 gtttggtgac gattcacaaa ttgatatccg gaaagggcgc catgctgtcg ttgaaaaggt
    39001 tatgggggct cagacctata ttccaaatac gattcagatg gcagaagata ccagtattca
    39061 actggttaca gggccaaaca tgagtgggaa gtctacctat atgcgtcagt tagccatgac
    39121 ggcggttatg gcccagctgg gttcctatgt tcctgctgaa agcgcccatt taccgatttt
    39181 tgatgcgatt tttacccgta tcggagcagc agatgacttg gtttcgggtc agtcaacctt
    39241 tatggtggag atgatggagg ccaataatgc catttcgcat gcgaccaaga actctctcat
    39301 tctctttgat gaattgggac gtggaactgc aacttatgac gggatggctc ttgctcagtc
    39361 catcatcgaa tatatccatg agcacatcgg agctaagacc ctctttgcga cccactacca
    39421 tgagttgact agtctggagt ctagtttaca acacttggtc aatgtccacg tggcaacttt
    39481 ggagcaggat gggcaggtca ccttccttca caagattgaa ccgggaccag ctgataaatc
    39541 ctacggtatc catgttgcca agattgctgg cttgccagca gaccttttag caagggcgga
    39601 taagattttg actcagctag agaatcaagg aacagagagt cctcctccca tgagacaaac
    39661 tagtgctgtc actgaacaga tttcactctt tgatagggca gaagagcatc ctatcctagc
    39721 agaattagct aaactggatg tgtataatat gacacctatg caggttatga atgtcttagt
    39781 agagttaaaa cagaaactat aaaaccaaga ctcactagtt aatctagctg tatcaaggag
    39841 acttctttga caattctcca cttttttgct agaataacat cacacaaaca gaatgaaaag
    39901 gagctgacgc attgtcgctc ccttttgtct attttttaag gagaaagtat gctgattcag
    39961 aaaataaaaa cctacaagtg gcaggccttg gcttcgctcc tgatgacagg cttgatggtt
    40021 gctagttcac ttctgcaacc gcgttatctg caggaagtat tagacgccct ccttactggg
    40081 aaatatgaag ctatttatag tatcggggct tggttgattg gtgtggccgt agtcggtcta
    40141 gttgctggtg gactcaatgt tgtcctcgca gcctatattg cccaaggagt ttcatccgac
    40201 cttcgggagg atgccttccg taaaattcaa accttttctt atgctgatat tgaacaattt
    40261 aatgcgggaa atctagtcgt tcgaatgaca aatgatatca accagattca gaacgttgtc
    40321 atgatgacct tccaaattct tttcagactt cccctcttgt tcatcggttc gtttatccta
    40381 gcggttcaaa ccttaccttc tctgtggtgg gtgattgttc tcatggtagt cttgattttt
    40441 ggtttgactg ctgtcatgat gggaatgatg gggcctcgtt ttgccaagtt tcaaaccctt
    40501 cttgagcgca tcaatgccat tgccaaggaa aatttacgtg gcgttcgtgt ggtcaagtcc
    40561 tttgtccaag aaaaagagca atttgctaag tttacagagg tctcagacga gctttttggt
    40621 caaaaccttt acattggtta tgccttttca gtagtggaac cctttatgat gttggttggt
    40681 tacggggcgg tcttcctctc tatttggctg gtcgcgggaa tggttcagtc ggatccgtct
    40741 gttgttggtt ccatcgcttc ttttgttaat tacctaagcc agattatctt taccattgtt
    40801 atggttggat ttttgggaaa ttctgtcagc cgtgccatga tttccatgcg tcgtattcga
    40861 gaaattcttg acgcagagcc agctatgacc ttcaaggata tcccagatga agagttggtt
    40921 ggaagcctta gctttgaaaa tgtgaccttt acctatccaa tggacaagga accgatgctg
    40981 aaagatgtga gctttactat tgaacctggt caaatggttg gtgtagttgg agcgactggt
    41041 gcaggaaagt caaccttggc tcaattgatt ccacgtctct ttgatccaca gaacggggcc
    41101 attaaaatcg gtggcaagga tattcgagaa gtgagtgaag gaaccctgcg taaaacagtt
    41161 tccatcgttc tccaacgtgc cattcttttt agtggaacga ttgcagataa cttgagacag
    41221 gggaagggaa atgctactct atttgaaatg gagcgcgcag ccaatattgc ccaggctagt
    41281 gaattcattc atcgtatgga gaaaaccttt gaaagtccag ttgaagaacg gggaaccaat
    41341 ttctctggtg gacaaaaaca aaggatgtcg attgcgcgtg ggattgtcag caatccacgt
    41401 attctgattt ttgacgattc gacctcagcc ttggatgcca aatcagagcg cttggtgcaa
    41461 gaagctttga ataaggactt gaaggggacg acaaccatta ttattgctca aaaaattagc
    41521 tcggttgtcc atgcagacaa gatcttggtt ctaaatcaag gacgattgat tggtcaaggc
    41581 acgcatgcag acttggttgc caacaatgcc gtttaccgtg aaatctatga aacacagaaa
    41641 tgaaagacaa actataagaa aagtcaatag ttttatctaa attatttctt atttcaattt
    41701 gatgatttgg cgatgatttt agagcacggc aaaaagccct tgaaaaagtc cattttttca
    41761 aaggtaatcc tgtgttgatt tcagaaatta catcactttt tgttcgtcaa atggcagctc
    41821 ttttttagga tataaaacag ggttcggata agtttttttg caaggtggat gatggctaca
    41881 ttgtaatgtt ttccttattc taacttagtc ttaagatagg ccttaaaagc aggtgaaaag
    41941 cgagggcatg ctttggcagc ttgtatgagt gcctaccgca gatgagggga accccgtttg
    42001 atcattcttc cagctaaatc aatctgatct gactgataaa tagaagaatc cagtccagcg
    42061 aaagcttgta attgagcaag attatcaaag gcatgaatat ttcgaatctc ggctaaaatg
    42121 accgccccta aacgattccc aatcccagta accgtcgtga tgatcgagtt gaactcagcc
    42181 atcaagtcat tgacacatgt ttccgccttg tcaatgagcc tcttgtaatg tttgatgttt
    42241 tcattacacg agataaaacg tttatgcgtt atcaaactca tgaccaattg aaacaaaaag
    42301 ctgtggttag atcctttcgg aaattgtcaa gcgattggag gaaatgaact aatccacagc
    42361 ggcttattcc aagtatacca cttgggcttt ggcagtagct aactgcgcta aatataatat
    42421 aaggaggagt aaaatgaaga cagttcaatt tttttggcat tattttaagg tttacaagtt
    42481 ctcatttgta gttgtcatcc tgatgattgt tctggcgact tttgcccaag ccctctttcc
    42541 agtcttttct ggacaagcgg tgacgcagct agccaattta gttcaagctt atcaaaatgg
    42601 caatccagaa cttgtatggc aaagcctatc aggaatcatg gtcaatcttg gcctgctggt
    42661 tttggttcta tttatctcta gtgtaatata catgtgtctc atgacgcgcg tgattgcaga
    42721 atcgaccaac gagatgcgca aaggcctctt tggtaagctt gctcagttga cggtttcttt
    42781 ctttgaccgt cgacaagatg gcgatatcct gtctcatttt accagtgatt tggataatat
    42841 cctccaagcc tttaacgaaa gcttgattca ggtcatgagc aatattgttt tatacattgg
    42901 tctgattctt gtcatgtttt cgagaaatgt gacgctggct ctcatcacca ttgccagcac
    42961 cccattggct ttccttatgc tgattttcat cgtgaaaatg gcacgcaaat acaccaacct
    43021 ccagcagaaa gaggtaggga agctcaacgc ctatatggat gagagcatct caggccaaaa
    43081 agccgtgatt gtgcaaggaa ttcaagagga tatgatggca ggatttcttg aacaaaatga
    43141 gcgcgtgcgc aaggcaacct ttaaaggaag aatgttctca ggaattcttt tccctgtcat
    43201 gaatgggatg agcctgatta atacagccat cgtcatcttt gctggttcgg ctgtactttt
    43261 gaatgataag tctattgaaa caagtacagc cctaggtttg attgttatgt ttgcacaatt
    43321 ttcacagcag tactaccagc ctattatcca agttgcagcg agttggggaa gtcttcagtt
    43381 ggcctttact ggagctgaac gaattcagga aatgtttgat gcagaggagg aaatccgacc
    43441 tgaaaaggct ccaaccttca ctaagttgca agaaagtgtt gaaatcagtc atatcgattt
    43501 ttcatacttg cctgataaac ctattttgaa agatgtcagc atttctgccc ctaaaggcca
    43561 gatgacagca gttgttgggc cgacaggttc aggaaaaacg actattatga acctcatcaa
    43621 tcgcttttat gatgttgatg ctggtggtat ttattttgat ggtaaagaca ttcgtggcta
    43681 tgacttagat agtcttagaa gcaaggtggg aattgtattg caagattcgg tcttgtttag
    43741 cggaacgatt cgagacaata tccgatttgg tgtgccagat gctagtcagg aaatggttga
    43801 ggtagcagca aaagcaaccc acattcacga ctatatcgaa agtttgcctg ataagtacga
    43861 tactcttatt gatgatgacc agagcatctt ttcaacaggg cagaagcaat tgatttcaat
    43921 cgctcgaacc ctgatgacag atccagaagt tctcattctc gatgaagcaa cttcaaacgt
    43981 agatacggtg acagaaagca agattcagca tgccatggag gtggttgtag caggtagaac
    44041 tagtttcgtc attgcccacc gcttgaaaac cattctcaat gcagatcaga ttattgtcct
    44101 taaagatgga gaagtcattg aacgtggtaa ccaccatgaa cttttgaagc taggtggctt
    44161 ttattcagaa ctctatcaca atcaatttgt tttcgaataa gaaagaagtt gtcctatgtg
    44221 ggcagctttt tcttgtccat aaaaaatctt tatcacagcc ttaaaaaaaa catattagac
    44281 gaaagtcatt ttgagtgata tgataggact atcgttagca ttcgaaagga gaggcatcat
    44341 ggctagaacg gttgtaggag ttgctgcaaa tctatgtccc gtagacgcag aaggcaaaat
    44401 cattcattca tctgtatctt gtagattcgc agagatcatt cgtcaagtcg gtggtctccc
    44461 tttagtcatt cctgttggtg atgagtcagt tgtacgtgat tatgtggaaa tgattgacaa
    44521 actcattttg acaggaggcc aaaatgttca tcctcagttt tatggagaga aaaagaccgt
    44581 cgagagcgat gattacaatc tggtccgtga cgaatttgaa ttggcactct tgaaggaagc
    44641 gcttcgtcag aataaaccaa ttatggcaat ctgtcgcggt gtccaacttg tcaatgttgc
    44701 ctttggtgga accctcaatc aagaaatcga aggtcactgg caaggactac ctttcgggac
    44761 atctcactct attgagacag tagaaggaag cgtggtggct aagctatttg ggaaagaaag
    44821 tcaggtcaac tcagtccatc gtcaaagcat taaagatttg gcacctaatt tccgtgtaac
    44881 tgctattgat tcaagagacc aaactattga agcgattgag tctatcgacg agcaccgcat
    44941 tatcggttta cagtggcatc cagagtttct ggttaatgaa gaagatggca atttagaatt
    45001 atttgagtat ttattgaatg aactgtaacg attggaacat ctggtcgttc tttcttttat
    45061 tttttcaaaa tttttagaat gtggcatttt acgcaaacgt ttgaattctg ataaaaattg
    45121 gagaaattcg acaaaaaaac ttgaaaaaaa cgaaggtaag cgttatgata gaaaagaaga
    45181 aatattggag gaagaacatg tcacatatta aatttgatta ttcaaaagtt ttagacaaat
    45241 ttgttgcacc acatgaagtg gaatacatgc aatcacaagt aacagcagca gatgaattga
    45301 tccgtaaagg aactggtgct ggtagcgact tcttgggatg gttggacctt cctgaaaaat
    45361 acgatcgcga agaatttgac cgcatcttga aagctgctga gcaaatcaag tcagacagcg
    45421 atgttttggt tgtgatcggt attggtggat cttaccttgg tgcaaaagca gcaatcgact
    45481 tcttgaatca ccattttgct aacttgcaaa caaaagaaga acgcaaagct ccacaaatcc
    45541 tttacgcagg aaactcaatc tcatctactt accttgctga cttggtagag tatgttgcag
    45601 acaaagactt ctcagtaaac gtaatttcta aatcaggtac aacaactgaa ccagcgattg
    45661 ctttccgtgt ctttaaagaa ctcttggtta agaaatacgg tcaagaagaa gctaacaaac
    45721 gtatctatgc aacaactgac cgccaaaagg gtgctgttaa ggttgaagca gacgctaacg
    45781 gttggggaac atttgttgtt ccagatgata tcggtggacg cttctcagta ttgacagccg
    45841 ttggtttgct tccaatcgca gcatcaggag ctgacatcaa agctcttatg gaaggtgcga
    45901 atgcagctcg caaagactac acttcagaca aaatctctga aaacgaagct taccaatacg
    45961 cagctgttcg taacatcctt tatcgtaaag gctatgcaac tgagatcttg gtaaactatg
    46021 agccatcact tcaatacttc tcagaatggt ggaaacaatt ggctggtgaa tcagaaggaa
    46081 aagaccaaaa aggtatctac ccaacttcag ccaacttctc aactgacttg cactcacttg
    46141 gtcaatttat ccaagaagga actcgtatca tgtttgaaac agttgtccgt gttgacaaac
    46201 ctcgtaaaaa cgtgcttatt cctactttgg aagaagacct tgacggactt ggttaccttc
    46261 aaggaaaaga cgttgacttt gtaaacaaaa aagcaactga cggtgttctt cttgcccaca
    46321 cagatggtga tgtaccaaac atgtatgtga ctcttccaga gcaagacgct ttcactcttg
    46381 gttacactat ctacttcttc gaattggcaa ttgccctttc aggttacttg aatgctatca
    46441 acccatttga ccaaccaggt gttgaagctt ataaacgtaa catgtttgcc cttcttggaa
    46501 aaccaggatt tgaagaattg agcaaagaac ttaacgcacg tctataatag aagaaaagag
    46561 tggtttgccc actcttttta ctctctttat ccatagaaat tggactcagc caagacttgt
    46621 gatataatat agaaagcaaa aaggcagacg cctagataat aggagaaact atgtcaaaag
    46681 atatccgcgt acgttacgca ccaagtccaa caggactact acacatcgga aatgctcgta
    46741 cagcattgtt taattacttg tatgcgcgcc atcatggtgg aacatttctc atccgtatcg
    46801 aagatactga ccgtaaacgc catgtcgagg atggtgaacg ttcacaactt gaaaaccttc
    46861 gctggttagg catggattgg gatgaaagtc cagaatcaca tgagaattat cgccagtctg
    46921 agcgtttgga cttgtatcaa aaatacatcg accaactatt agctgaagga aaagcctaca
    46981 aatcttacgt tacagaagaa gagttggtag ctgaacgtga acgtcaagaa gtagctggcg
    47041 aaacaccacg ctacatcaat gaataccttg gtatgagtga agaagaaaaa gcagcttaca
    47101 tcgcagaacg tgaagcagca gggatcatcc caactgttcg tttggctgtc aatgagtcag
    47161 gtatctacaa gtggcatgat atggtcaaag gcgatatcga atttgaaggt ggcaatatcg
    47221 gtggtgactg ggttatccaa aagaaagacg gttacccaac ttacaacttt gccgttgtta
    47281 tcgatgacca cgatatgcaa atctctcatg ttatccgtgg agatgaccat attgctaata
    47341 caccaaaaca gcttatggtc tatgaagctc ttggttggga agctccagag ttcggtcaca
    47401 tgaccttgat tatcaactct gagactggta agaagttatc taaacgtgat actaatacac
    47461 ttcaatttat cgaagattac cgaaagaaag gttaccttcc agaagcagtc tttaatttta
    47521 ttgctcttct tggttggaac ccaggtggtg aagatgagat tttctctcgt gaagaactca
    47581 ttaaactttt tgatgaaaac cgcctcagca agtcaccagc agcctttgat cagaaaaaac
    47641 tagactggat gagcaatgat tatatcaaga atgcagacct tgaaaccatc tttgaaatgg
    47701 caaaaccatt cttagaggaa gcaggccgtt tgactgacaa ggctgaaaaa ttagttgagc
    47761 tctataaacc acaaatgaaa tcagtagatg agattatccc attgacagat cttttcttct
    47821 cagatttccc agaattgaca gaagcagagc gcgaagtcat gacgggtgaa acagttccaa
    47881 cagttcttga agcattcaaa gcaaaacttg aagcgatgac agatgataaa tttgtgacag
    47941 aaaatatctt cccacaaatt aaagcagttc aaaaagaaac aggtattaaa gggaaaaatc
    48001 ttttcatgcc tattcgtatc gcagtttcag gcgaaatgca tgggccagaa ttaccagata
    48061 caattttctt gcttggacgt gaaaaatcaa ttcagcatat cgaaaacatg ctaaaagaaa
    48121 tctctaaata aagaggatac aataatggac atctgggaaa agatgtacga agaagcacag
    48181 aaactataca atccacatga agtatcagac tttgtttatg ccaatcatgt tgtagctgca
    48241 gtagaagcag aagatggaca aatatttaca ggattctgta tggagggaac ctgtggtgtt
    48301 ttccatctct gcgcagaacg ggcggccctc tttaatacgt accaattttc aggacaaact
    48361 aaggttaaga aagtattagc ctttcgagac aaaccacctt atggtggaag ttcagccatg
    48421 ccttgcggtg cttgtagaga attcctttta gagcttaatg ctgaaaataa agatgcagaa
    48481 ttcatgatgg actataatat aagaaaaaca gttaaagtcg cagaactaat cccttattgg
    48541 tgaggagaag aacgtgcttc taagtttaat gagcgataga agagtcagta taattctggc
    48601 tttttttact at
//
LOCUS       DAVLTT010000010        46958 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLTT010000010 DAVLTT010000000
VERSION     DAVLTT010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46958
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.010"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(46..813)
                     /locus_tag="VYN15_000615"
     CDS             complement(46..813)
                     /locus_tag="VYN15_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HEV1451976.1"
                     /translation="MTNTAKKLTILSANLNFYMSNKVQKKTSEKIVKMLLSEEQNPKP
                     TFIALQEVGNRVIYKVEKDEIEDYSVNIERIENKLFNEGYGVIRPKQYGKEKDASNPV
                     NTRLFYLKKSVESIKELTPLGLGIKEDFYNRQCGGIFTINNQTIAVYSLHFKWQKDER
                     GAFWKKYIEIAESNKYNHLILAGDFNESLINVTTELSDKITKMKNYMVDASHDLPTWK
                     DKQLDHIFITPNTKIENYSTLDNDFSDHKALQVTIIV"
     gene            1218..1718
                     /locus_tag="VYN15_000616"
     CDS             1218..1718
                     /locus_tag="VYN15_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451977.1"
                     /translation="MKNERRERWTQLSSQRMSRVLWTIELIANLSSHNYEYKDEWLGY
                     LFDSIKQKGDEIKEVFQNPTDALSNKLISEFEFPKEMFRSQPSPKELKFKNVAERRIT
                     KLYKEMNYFSRLANTKNYTYDSIDVDFLFDCYSNKYYELVSWFPPFIKDRVCNDINVA
                     DFPSER"
     gene            1746..2024
                     /locus_tag="VYN15_000617"
     CDS             1746..2024
                     /locus_tag="VYN15_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451978.1"
                     /translation="MNYWNDIKNIITEWHSIDYRVTEREDFETVKLRAIRDFQHYLKL
                     LDENTEEGYQEVIRLFTFSKFYGEELCNDEKLNKLSRDIRGRLKQFRS"
     gene            2286..3563
                     /locus_tag="VYN15_000618"
     CDS             2286..3563
                     /locus_tag="VYN15_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV1451979.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            3639..5123
                     /locus_tag="VYN15_000619"
     CDS             3639..5123
                     /locus_tag="VYN15_000619"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV1451980.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALRERLAA
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNDAVKTAELMNALNTQGQYELTDFDAEILELFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTNDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVCHKTTVAAADMQVAVEAYLGL"
     gene            5184..6464
                     /locus_tag="VYN15_000620"
     CDS             5184..6464
                     /locus_tag="VYN15_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1451981.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMILKG"
     gene            6468..7091
                     /locus_tag="VYN15_000621"
     CDS             6468..7091
                     /locus_tag="VYN15_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1451982.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFEAER"
     gene            7253..8431
                     /locus_tag="VYN15_000622"
     CDS             7253..8431
                     /locus_tag="VYN15_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1451983.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALDVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVALSTDSTTPEGQPAETTSPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATETTATSSEAKEVASSNGATAAVSTYQPEETKTISTTYEAPAAPDYAGLAVAK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            8859..9284
                     /locus_tag="VYN15_000623"
     CDS             8859..9284
                     /locus_tag="VYN15_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1451984.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            9295..9663
                     /locus_tag="VYN15_000624"
     CDS             9295..9663
                     /locus_tag="VYN15_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEV1451985.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELA
                     HPSVSLLFKNQGIYKALLGVFLLYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            9770..10413
                     /gene="pcp"
                     /locus_tag="VYN15_000625"
                     /pseudo
     CDS             9770..10413
                     /gene="pcp"
                     /locus_tag="VYN15_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(10440..11297)
                     /locus_tag="VYN15_000626"
     CDS             complement(10440..11297)
                     /locus_tag="VYN15_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV1451986.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            11427..12569
                     /gene="tgt"
                     /locus_tag="VYN15_000627"
     CDS             11427..12569
                     /gene="tgt"
                     /locus_tag="VYN15_000627"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV1451987.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            12670..14487
                     /locus_tag="VYN15_000628"
     CDS             12670..14487
                     /locus_tag="VYN15_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1451988.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            14640..15791
                     /gene="nagA"
                     /locus_tag="VYN15_000629"
     CDS             14640..15791
                     /gene="nagA"
                     /locus_tag="VYN15_000629"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV1451989.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVGDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            15954..17012
                     /locus_tag="VYN15_000630"
     CDS             15954..17012
                     /locus_tag="VYN15_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1451990.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLDTAVSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            17163..17528
                     /locus_tag="VYN15_000631"
     CDS             17163..17528
                     /locus_tag="VYN15_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV1451991.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            17604..18545
                     /locus_tag="VYN15_000632"
     CDS             17604..18545
                     /locus_tag="VYN15_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV1451992.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            18493..19509
                     /locus_tag="VYN15_000633"
     CDS             18493..19509
                     /locus_tag="VYN15_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV1451993.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            19511..19837
                     /gene="comGC"
                     /locus_tag="VYN15_000634"
     CDS             19511..19837
                     /gene="comGC"
                     /locus_tag="VYN15_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV1451994.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQVDGRITEEQAKAYKEYHDKNGGA
                     NRKVND"
     gene            19830..20234
                     /locus_tag="VYN15_000635"
     CDS             19830..20234
                     /locus_tag="VYN15_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV1451995.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTNLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            20239..20499
                     /locus_tag="VYN15_000636"
     CDS             20239..20499
                     /locus_tag="VYN15_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1451996.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            20462..20923
                     /locus_tag="VYN15_000637"
     CDS             20462..20923
                     /locus_tag="VYN15_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1451997.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            20901..21311
                     /locus_tag="VYN15_000638"
     CDS             20901..21311
                     /locus_tag="VYN15_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1451998.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKSEEKPEKKENS"
     gene            21448..22035
                     /locus_tag="VYN15_000639"
                     /pseudo
     CDS             21448..22035
                     /locus_tag="VYN15_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            22096..23049
                     /locus_tag="VYN15_000640"
     CDS             22096..23049
                     /locus_tag="VYN15_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1451999.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGAIFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            23100..24290
                     /locus_tag="VYN15_000641"
     CDS             23100..24290
                     /locus_tag="VYN15_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV1452000.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            24439..24810
                     /gene="rnpA"
                     /locus_tag="VYN15_000642"
     CDS             24439..24810
                     /gene="rnpA"
                     /locus_tag="VYN15_000642"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV1452001.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYQEGNGSEKETKVD"
     gene            24785..25609
                     /locus_tag="VYN15_000643"
     CDS             24785..25609
                     /locus_tag="VYN15_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1452002.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNEVTSDITADSADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            25628..26614
                     /locus_tag="VYN15_000644"
     CDS             25628..26614
                     /locus_tag="VYN15_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV1452003.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     ANRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            26665..27288
                     /locus_tag="VYN15_000645"
     CDS             26665..27288
                     /locus_tag="VYN15_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV1452004.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            27419..28876
                     /locus_tag="VYN15_000646"
     CDS             27419..28876
                     /locus_tag="VYN15_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1452005.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSFMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            28899..29180
                     /locus_tag="VYN15_000647"
     CDS             28899..29180
                     /locus_tag="VYN15_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1452006.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            29257..29742
                     /locus_tag="VYN15_000648"
     CDS             29257..29742
                     /locus_tag="VYN15_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1452007.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELDDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            29759..30424
                     /locus_tag="VYN15_000649"
     CDS             29759..30424
                     /locus_tag="VYN15_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV1452008.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            30428..31291
                     /locus_tag="VYN15_000650"
     CDS             30428..31291
                     /locus_tag="VYN15_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV1452009.1"
                     /translation="MVRPIGIYEKATPTHCTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            31293..31997
                     /locus_tag="VYN15_000651"
     CDS             31293..31997
                     /locus_tag="VYN15_000651"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV1452010.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKTWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            32176..33849
                     /locus_tag="VYN15_000652"
     CDS             32176..33849
                     /locus_tag="VYN15_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1452011.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            33961..35052
                     /gene="ulaG"
                     /locus_tag="VYN15_000653"
     CDS             33961..35052
                     /gene="ulaG"
                     /locus_tag="VYN15_000653"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV1452012.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKINVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            35166..37142
                     /gene="tkt"
                     /locus_tag="VYN15_000654"
     CDS             35166..37142
                     /gene="tkt"
                     /locus_tag="VYN15_000654"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1452013.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASVYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            37259..37558
                     /gene="yajC"
                     /locus_tag="VYN15_000655"
     CDS             37259..37558
                     /gene="yajC"
                     /locus_tag="VYN15_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1452014.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            37605..38033
                     /locus_tag="VYN15_000656"
     CDS             37605..38033
                     /locus_tag="VYN15_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV1452015.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            38035..38445
                     /locus_tag="VYN15_000657"
     CDS             38035..38445
                     /locus_tag="VYN15_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452016.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            38746..41397
                     /gene="adhE"
                     /locus_tag="VYN15_000658"
                     /gene_synonym="adhC"
     CDS             38746..41397
                     /gene="adhE"
                     /locus_tag="VYN15_000658"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV1452017.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(42305..42613)
                     /locus_tag="VYN15_000659"
     CDS             complement(42305..42613)
                     /locus_tag="VYN15_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1452018.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEVHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(42610..42918)
                     /locus_tag="VYN15_000660"
     CDS             complement(42610..42918)
                     /locus_tag="VYN15_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1452019.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(42923..44218)
                     /locus_tag="VYN15_000661"
     CDS             complement(42923..44218)
                     /locus_tag="VYN15_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1452020.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGIVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(44236..45645)
                     /locus_tag="VYN15_000662"
     CDS             complement(44236..45645)
                     /locus_tag="VYN15_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1452021.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            45803..46531
                     /locus_tag="VYN15_000663"
     CDS             45803..46531
                     /locus_tag="VYN15_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1452022.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
BASE COUNT        14484 a         8304 c        10057 g        14113 t
ORIGIN      
        1 aaaactgcaa cggttctaat tttaaataat ttcatttcgg aactcctaaa ctataatagt
       61 cacctgcaaa gctttgtggt cactgaaatc attatcgaga gttgaatagt tttcgatttt
      121 ggtatttggt gtgataaaaa tgtgatcaag ttgtttatcc ttccatgttg gtaagtcatg
      181 actggcatct accatataat ttttcatttt tgttattttg tcagacaatt cagtagttac
      241 attgattaag ctctcgttaa aatcgcccgc caaaataaga tgattatact tgttagactc
      301 agcaatttca atatattttt tccaaaatgc acctctttca tctttttgcc atttgaaatg
      361 aagagagtaa actgcaatag tttggttatt gatagtaaaa ataccaccac attgtctatt
      421 atagaaatct tcttttattc ctaatcctaa gggagttaat tctttgatag attcaactga
      481 tttttttaag taaaacaatc gagtatttac aggattgctc gcatcttttt cttttccata
      541 ttgcttaggg cgtatcactc cgtatccttc attaaatagt ttattttcta ttcgttctat
      601 attcacactg taatcttcaa tttcatcttt ttctacttta taaataacgc gattacccac
      661 ctcctgcaat gctataaaag ttggtttggg gttttgttcc tctgacaata acatttttac
      721 gatcttttct gatgttttct tctggacttt attactcata taaaagttta aattggcact
      781 caaaatagtt aatttttttg ctgtattagt cataacagag ttcctcctgt tgatagatat
      841 tttttatttt aggttaaatt ttagttcaat tattgatatt tatttggtga ttctctactt
      901 gtcgcgatag atttcatttt tatgttaatt atcaaatctg tcccatgttt cacagtcatc
      961 tttgatgtca tcttcattac aaagtagaac atcataaaaa taatcgaaag cttcttgttc
     1021 ttctactacc atggcaaaca cctcatatat aggcttgtaa acctttttta ttaaatatgt
     1081 aatataatta tataccatac aaaggtatcg gtcaagcaaa aaaccttatt aattagaata
     1141 aaaatattta gggttttatt tttacggatt ttgatatata atatcattta gtattatttt
     1201 ataattagga gaagacaatg aaaaatgaac gcagagagcg atggacacag cttagctcac
     1261 aaagaatgtc acgagtatta tggacaatag aattaattgc aaatctatct agtcacaact
     1321 atgaatataa agatgaatgg cttggatatt tatttgattc aatcaagcag aaaggagatg
     1381 agataaaaga agtatttcaa aatcctaccg atgcattatc taataaattg atttcagaat
     1441 ttgaatttcc aaaagaaatg tttcgttctc aacctagccc aaaagaatta aaatttaaaa
     1501 atgttgcaga aagaagaatt actaagctat ataaagaaat gaactatttt agccgattgg
     1561 ctaataccaa aaattataca tacgactcta ttgatgttga ctttctattt gattgttact
     1621 caaataaata ctacgaattg gtgagctggt ttcctccatt tataaaagac agagtttgca
     1681 atgatattaa cgtagctgat tttccaagtg aaagatagtt aaattctatg atttggagaa
     1741 ggaaaatgaa ctattggaat gatattaaaa atataataac agaatggcac tctattgatt
     1801 acagagttac ggaacgagaa gattttgaaa cagtaaaact aagagcaatt agagattttc
     1861 aacattatct aaaattactt gatgaaaaca ctgaagaagg ataccaagaa gttataagat
     1921 tatttacatt cagcaaattc tatggtgaag aactgtgtaa tgatgaaaaa ctgaacaaat
     1981 tgagtagaga tataagaggg agattaaaac aattccgttc ctaaaatgtt actaaaaata
     2041 aaaaaactat cgtttttgtg atagaggtaa ctttttgaaa aggctatttg actggcttta
     2101 tatacttatg aaacgttaag agtccaactc aaaatccagt gtccgcaagg acgtgccggt
     2161 tcgaccccgg ccgccggtat agtatagtgt taggaacgtt gttattcttc gttccttttt
     2221 tatattattt ttggtataat tatagttatt caaattttgt ttagattgag aaagtgtagg
     2281 gtagtatgtc ttgttctatc gatttattaa aacatcggta tttgaaaaat attaaagaaa
     2341 atcctgaatt gtttgtcgga attgagttgg agtatcctgt tgcaagttta gaaggggatg
     2401 ctacagatgt tgaagttata aaggatctat ttcattattt agtttctact ttggatctca
     2461 ccgtagcaaa ggtagatgat tttggcaatc tgatccagtt agtagatccg ataagtcagg
     2521 atgctatttt atttgaagtt tcctatacaa cgattgagtt tgcatttggt aaggctgaaa
     2581 cgattcaaga ggtcgaaaat cgtttcaata attatatgaa tgtaattcag agaaagttag
     2641 ctgaatcaaa tcatgctatt gttggctgtg gtatccatcc caactgggat aaaaatgaga
     2701 attgtccagt ggcttatcca cgctatcaga tgttgatgga ttatttgaat ttgagtagaa
     2761 atattattaa atcagattta catcatttcc ctgaatatgg tacttttatc tgtgggagcc
     2821 aggttcagct ggatatttca aaaaccaact acttacgggt gattaatgct tttactcaaa
     2881 ttgaagcggc taaggcttat ttatttgcaa actctgaatt ttcgggtgcg gattgggata
     2941 cgaaaatttc aagggatatt ttctgggaag aatctatgca tggtatctat ccagagaatg
     3001 ttggggtcaa tgctagactc cttaatgatg aagctgattt ttttgactat ctaaatcatt
     3061 ctgcgatttt tactgcggaa cgtgatgggc agacctatta tttttatcct attcaggctg
     3121 gggactattt ggctacgcct gaaatccaag catttgctct gaatggggat gaggttatta
     3181 tttaccccca agagaaggat tttgaaactc atcgtagtta ccagtaccaa gacttaacga
     3241 ctcgaggaac agttgagttt cgtagtgtgt gtacacagcc acttgatagg acttttgctt
     3301 ctgcagcttt tcacttggga ttattggtta atttagacaa gttagaagct tacttagaaa
     3361 cagcaccttt ctttaaagta tttggttatg attacaagtc tttaaggaga caattttcta
     3421 agaaaaatct tacagatgag gaagaaacta cgattattga attttccaaa gacttactcc
     3481 tactagctga ggagggacta gtggtgagaa ataaggaaga aatgacctat ttacagcctt
     3541 tgagagaaga attgagccta taatttctct tataaaggga gaattttctg aaaaatcatg
     3601 atataatgga cgagactata gataaaggat agagagtaat gacattagtt tatcaatcaa
     3661 cgcgtgatgc caacaataca gtaactgcca gccaagcaat tttgcaaggt ttggcgacgg
     3721 acggcggttt gtttacaccg gttacttatc caaaggtaga tttggacttt gacaaattga
     3781 aagatgcttc ttaccaggaa gttgctaagc tagttttgtc agcattttta gatgacttta
     3841 cagctgagga gttggactac tgtatcaaca atgcctacga tagcaaattt gatactccag
     3901 ctattgcacc attagtgaaa ttagatgggc aatacaattt ggaacttttc catggttcaa
     3961 cgattgcctt taaggatatg gccttgtcta ttttgccata ctttatgacg actgctgcta
     4021 agaaacatgg tttggagaac aagattgtta tcttgacagc gacatctggt gacacgggga
     4081 aagctgctat ggcggggttt gcggatgtgc ctggtactga gattatcgtc ttttatccaa
     4141 agggtggtgt cagcaaggta caagagttgc aaatgaccac tcagaatggt gacaatactc
     4201 atgttatcgc tatagatggt aactttgacg atgcgcaaac caacgtgaag cacatgttta
     4261 acgacgtggc tcttcgtgaa agattagcgg ccaacaagtt gcaattttca tctgctaact
     4321 ctatgaatat cggtcgtttg gtgccacaga ttgtttatta tgtttatgcc tatgctcagt
     4381 tggtcaagac tggtgagatc gtggctggtg ataagattaa cttcacagta ccaacaggaa
     4441 actttggaaa tatcttggct gccttttatg ccaaacaaat cggtctccca gttggtaaat
     4501 tgatctgtgc ttcaaatgac aacaatgttt tgacagactt cttcaagaca cgtgtttacg
     4561 acaagaaacg tgagtttaag gtaacaacca gcccatctat ggatatcttg gtatcttcaa
     4621 acttggagcg tttgattttc catcttttgg ggaatgatgc ggttaagacg gctgaactca
     4681 tgaatgcctt gaatacacaa ggacaatatg aactgactga ttttgatgca gagattctgg
     4741 agctctttgc agctgaatat gcgactgagg aagaaacagc ggcagaaatc aagcgtgttt
     4801 atgagttaga ttcttatatt gaggatccac atacggcggt tgcctcagca gtttatagaa
     4861 aataccaagc ggttactaat gatgcgacta agacagtgat tgcttcaaca gctagtccct
     4921 acaagttccc agtagttgca gtagaagctg taactggaaa agcaggttta acagactttg
     4981 aagctttggc tcaattacat gaaatctcag gcgttgcagt gccaccagca gttgatgggc
     5041 ttgagacagc tcctgtttgt cacaagacaa cagtggcagc tgctgacatg caagtagcgg
     5101 ttgaggctta tttaggactt taagatagag ggagtaaact cggttgggaa accaactgag
     5161 tttcttttca tcaggaggag agattgttta agaaaaataa agacattctt aatattgcat
     5221 tgccagctat gggtgaaaac tttttgcaga tgctaatggg aatggtggac agttatttgg
     5281 ttgctcattt aggattgata gctatttcag gggtttcggt agctggtaat attatcacca
     5341 tttatcaggc gattttcatc gctctgggag ctgctatttc cagtgttatt tcaaaaagca
     5401 tagggcagaa agaccagtcg aagttggcct atcatgtgac tgaggcgttg aagattacct
     5461 tactattaag tttcctttta ggatttttgt ccatcttcgc tgggaaagag atgataggac
     5521 ttttggggac ggagagggat gtagctgaga gtggtggact gtatctatct ttggtaggcg
     5581 gatcgattgt tctcttaggt ttaatgacta gtctgggagc cttgattcgt gcaacgcata
     5641 atccacgtct gcctctctat gttagttttt tatccaatgc cttgaatatt cttttttcaa
     5701 gtctagctat ttttgttctg gatatgggga tagctggtgt tgcttggggg acaattgtgt
     5761 ctcgtttggt tggtcttgtg attttgtggt cacaattaaa actgccttat gggaagccaa
     5821 cttttggttt agataaggaa ctgttgacct tggctttacc agcagctgga gagcgactta
     5881 tgatgagggc tggagatgta gtgatcattg ccttggtcgt ttcttttggg acggaggcag
     5941 ttgctgggaa tgcaatcgga gaagtcttga cccagtttaa ctatatgcct gcctttggcg
     6001 tcgctacggc aacggtcatg ctgttggccc gagcagttgg agaggatgat tggaaaagag
     6061 ttgctagttt gagtaaacaa accttttggc tttctctgtt cctcatgttg cccctgtcct
     6121 ttagtatata tgtcttgggt gtaccattaa ctcatctcta tacgactgat tctctagcgg
     6181 tggaggctag tgttctagtg acactgtttt cactacttgg gacccctatg acgacaggaa
     6241 cagtcatcta tacggcagtc tggcagggat taggaaatgc acgcctccct ttttatgcga
     6301 caagtatagg catgtggtgt atccgcattg gaacaggata tctgatgggg attgtgcttg
     6361 gttggggctt acctggtatt tgggcagggt ctctcttgga taatggtttt cgctggttat
     6421 ttctacgcta tcgttaccag cgctatatga tcttgaaagg ataggaaatg caaaaaacag
     6481 cttttatttg ggatttagac gggactttat tggactctta cgaagcgatt ttatcaggga
     6541 ttgaggagac ttttgctcag ttttctattc cttatgataa ggagaaggtg agagagttta
     6601 tcttcaagta ttcggtgcaa gatttgcttg tgcgggtggc agaagataga aatctggatg
     6661 ttgaggtgct aaatcaggtg cgtgcccaga gtctggctga gaagaatgct caggtagttt
     6721 tgatgccagg tgcgcgtgag gtgctagctt gggcagacga atcaggaatt cagcagttta
     6781 tatatactca taaggggaac aacgctttta ccattctcaa ggacttgggg gtggaatcct
     6841 attttacaga gattttaacc agtcagagtg gctttgtgcg gaagccaagt ccagaagcgg
     6901 ctacctatct gctagataag tatcagttga attctgataa tacttattat ataggggatc
     6961 ggactctgga tgtggaattt gcccagaata gtgggattca aagtatcaac tttttagagt
     7021 ctacttatga agggaatcac aggattcaag cgttagcaga tatttcccgt atttttgagg
     7081 ctgaacgata aaaagattgt gtcagttttg tgacagagac ctaacaaact atttcaagta
     7141 acctagtttg ttacaaggaa tagacagttc tgttaaatag gcccgagagg gctttttttc
     7201 tacatttttt gtgttatcat agacaggtac tcatttgaaa ggatttgaaa gaatgaagaa
     7261 aagaatgtta ttagcgtcaa cagtagcctt gtcatttgcc ccagtattgg caactcaagc
     7321 agaagaagtt ctttggactg cacgtagtgt tgagcaaatc caaaacgatt tgactaaaac
     7381 ggacaacaaa acaagttata ccgtacagta tggtgatact ttgagcacca ttgcagaagc
     7441 cttggatgta gatgtcacag tgcttgcgaa tctgaacaaa atcactaata tggacttgat
     7501 tttcccagaa actgttttga caacgactgt caatgaagca gaagaagtaa cagaagttga
     7561 aatccaaaca cctcaagcag actctagtga agaagtgaca actgcgacag cagatttgac
     7621 cactaatcaa gtgaccgttg atgatcaaac tgttcaggtt gcagaccttt ctcaaccaat
     7681 tgcagaagct ccaaaagaag tagcatcaaa ttcagaagtt gcagagacag tgactgctgc
     7741 agaagaagtg gcactatcta cagactctac tacgccagag ggacaaccag ccgaaacaac
     7801 tagtccagtt gaagaagtag ctcctcaggc aacgactcta gctgagaagc aggaaacaca
     7861 agtgagctct caaaccgagt cagcagtgga agcaactaca atgccagtag aagaaaaagc
     7921 aaccgaaaca actgcaacaa gttcagaagc aaaagaagta gcatcatcaa atggagctac
     7981 agcagcagtt tctacttatc aaccagaaga gacgaaaaca atttcaacaa cttacgaggc
     8041 tccagctgcg cccgattatg ctggactggc agtagcgaaa tctgaaaatg caggtcttca
     8101 accacaaaca gctgccttta aagaagaaat tgctaacttg tttggcatta catcctttag
     8161 tggttatcgt ccaggagaca gtggagatca cggaaaaggt ttggctatcg actttatggt
     8221 accagaaagt tcagaattag gggataagat tgcggaatat gctattcaaa acatggccag
     8281 ccgtggcatt agttacatca tctggaaaca acgtttctat gctccattcg atagcaaata
     8341 tgggccagct aacacttgga acccaatgcc agaccgtggt agtgtgacag aaaatcacta
     8401 tgaccacgtt cacgtttcaa tgaatggata aacccgactt ggtaacatca ttttgacgaa
     8461 tgagatctag ctttcgtgat aggaagcgat tctcgttcgt tttttctttg tcatactctt
     8521 cgaaaatctc ttcaaacaac gtcagtttta tctgaaacct caaagctgtg ctttgagcaa
     8581 cctgcgacta gcttcctagt ttgctttttg attttcattg agtatcaatt tgaatggaaa
     8641 atggaaagtt atcatcttgt aatgagttaa gcaacattct tgcaatctat tttatagtag
     8701 attgaaacta gaatagtaca caactgcttc taaaacattg ttagaaatcg atttgactgt
     8761 cctgatcgat ttgtcctgct cttatttcat ttcactatac tttatattat aattgactgg
     8821 tcaaatattg ataaatcaat aaaaagagag gggaagaaat gctagagatt caagatttac
     8881 tgtatcaact ccgcttgtct gagcaagcga gtacgcaatt gtttgaaaaa aggcttggga
     8941 ttagtttgac acggtatcag attttactgt ttttgctgga gcattctcct tgtaaccaaa
     9001 tggcggttca ggagcgtttg aaaattgatc aggctgcttt gacacggcat ttcaagattt
     9061 tggaaacgga aggtttggtg gagcgtcatc gtaatcctga aaatcagcgg gaagtgttgg
     9121 tagaggctgc gaagtatgcc aaggagcagt tagtggtgaa tccccctctg caacatatca
     9181 aggttaagga agagatggaa agtatcttaa cagagtttga gagaacagaa ctcagccgtt
     9241 tattaaataa attggttttg ggtattgaaa atatagaaat ttaaggagaa atagatgtca
     9301 attattacaa ttattttaac aacgatcgtt gctttggagc atttttacat tttttatttg
     9361 gaaagtattg ccacgcaatc agatgcgact agtcgtgtat ttaatatgga aaaggaagaa
     9421 ttggctcatc cgtcagtaag tttattgttc aaaaatcaag ggatttataa ggctctgcta
     9481 ggagtctttc tcttgtatgg catttatttc tcacagaatt tagaaattgt gactattttt
     9541 gtcttatttg tgattggtgc tgcgacttac ggctctttaa cagcggataa aaaaattatt
     9601 ttgaagcaag gtggatcagc tattttggcc ttgattagta ttttactctt taaatacact
     9661 tgaaggtcga ttctaatctc gctaatcctt ttcaatccag aataagggaa atatgttata
     9721 cttgttttta agaaaaaagt ctcattgaat tggttttgag gagttagaaa tgaaagtatt
     9781 agtgacaggt tttgagccct ttggagggga aaagggcaat ccagctttgg aggccattaa
     9841 aggtttacca gctgaaatcc atggtgctga ggtccgttgg ctagaggtgc ctacagtttt
     9901 tcacaaatct gctcaagtat tggaagaaga gatgaatcgt tatcaacctg actttgtcct
     9961 ttgtattggg caagctggtg gaagaactag tttgacacct gaacgagtgg ccattaatca
    10021 agacgatgca cgcatttctg ataacgaaga taatcaaccg attgaccgtc ccattcgccc
    10081 agatggtgct tcggcctact ttagtagttt gccgattaaa gcgatggttc aagctataaa
    10141 aaagaaggat taccggcctc tgtttccaat acggcaggga cttttgtctg cagccatttg
    10201 atgtatcagg ctctctattt ggtagaaaag aaatttccat atgttaaggc aggttttatg
    10261 catattcctt atatgatgga acaggtggtg aacagaccga ctactccaac tatgagttta
    10321 gtggatattc ggcgagggat agaagcagca atcggcgcta tgatagaaca tggagatcag
    10381 gaactcaagt tggtaggcgg agaaattcat tgatagaaaa aagcttgagg ggaaaacctt
    10441 caagcttttg gacgttttcg agccaatact gctcggtaaa acataatttt agtgcattgg
    10501 atataaggta ggagtgaaaa actagcaatg ccaaaggtaa tccaattgag gaagtaccaa
    10561 ggaagaagct gtaaatctag gacaaagtgc tggaacttgt agcccttcat aaaggaacgg
    10621 ctagttttta ggattcgtct tggtgggacc tgtcctaggt ctagactata acagagaaga
    10681 aattccacct gtgaataggc ataatactgt ggaatataga ggatattccc tacaatgatc
    10741 aagatgagac ttgcaagaaa gtagagtcca aagaccatga ggaaacgctc ggtttcaact
    10801 gatgagagat ctagatttgg aaactcagga tgtagggtga cgaatttttt ggctaaaaag
    10861 ctactataaa agaggaggta aatcccaagt aaattaggga tactccataa aaagagatag
    10921 aaacgtttga gaagtagggt caaaaaggtt tgagaaaagc gctcctcatc aaagagagct
    10981 aggctgtttt ttacagatgg ctccgtttta gaatctttca tgagtgtcag tgttgcatag
    11041 acggaactgg tcaaaagaat agtcccgata aaggagacta gtagaggaaa gaggtaggct
    11101 tgaagtattt ggccaagtat gctgaaaaat ggctgttcta aaacagtccc gtggatccga
    11161 gataagggat taagaaaact agataagatg accagcatac tgggaaggat atagaggaga
    11221 aagagacggg gggtgtcagc ctgaaaatgt tttgactcct gacgaattgt ttttaaatca
    11281 atttttggat agttcattct cttattatac catagttctt atacatagtt cgtgacagtt
    11341 cctacttttt ttgataaaat catacagtgt gtccttgggc acactgtatg aactgggact
    11401 gtctttccca gcttcggagg taaaaaatgt cagattcacc aatcaaatat cgtttgatta
    11461 agaaagaaaa acacacagga gctcgtctag gagaaatcat cactccccac ggtacctttc
    11521 cgacacctat gtttatgcca gttgggacac aagccactgt caaaactcag tcacctgaag
    11581 aattgaagga gatgggttcg ggaattatcc tatcaaacac ctatcatctc tggcttcgcc
    11641 ctggagatga actcattgca cgcgctggtg gtctccacaa gttcatgaat tgggaccagc
    11701 ctatcttgac agatagtggt ggttttcagg tttattcttt agcagatagc cgtaatatca
    11761 cagaagaagg agtaaccttt aaaaatcatc taaatggttc taagatgttc ctatccccag
    11821 aaaaagccat ctctattcag aataatctgg gttcagatat catgatgtcc tttgatgaat
    11881 gtcctcagtt ttatcaacct tatgactacg ttaagaaatc gatcgagcgt accagccgtt
    11941 gggctgagcg tggtttgaag gctcaccgtc gtccacatga ccaaggtttg tttggaattg
    12001 tgcaaggtgc aggatttgaa gaccttcgcc gccaatcagc tcatgatctt gtcagcatgg
    12061 atttctcagg ctactctatc ggtggtttgg cagtgggaga aacccatgaa gagatgaatg
    12121 cggtcttgga ctttacaact caactgctac ctgaaaataa acctcgttat ctgatgggtg
    12181 tgggagcgcc agatagcttg atcgatgggg tcattcgtgg ggtggatatg tttgactgtg
    12241 tcttaccgac tcgaattgct cgtaacggga cttgtatgac cagtcaagga cgtttggttg
    12301 tgaaaaatgc ccagtttgct gaggacttta cgccactgga tcctgagtgt gattgttaca
    12361 catgtaataa ctatacacgc gcttaccttc gtcacctgct caaggctgat gaaacctttg
    12421 gtatccgctt gactagctac cacaatcttt acttcttgct taacttgatg aagcaagtgc
    12481 gacaagccat catggatgac aatctcttgg aattccgtga gtattttgtg gaaaaatatg
    12541 gctataataa gtcaggacgt aatttctaaa atggaattga tataagctaa aaatcctaag
    12601 ttttctctta ggatttttct tctttttttg atagaataaa gtgtacaatg aaaggaagaa
    12661 taaactcgta tgcgcattaa atggttttcc ttggttagga ttacaggttt acttttggta
    12721 ctcttgtatc acttctttca gacgatcttt cctggaggat ttttcggggt agatgtcttt
    12781 ttcacatttt caggtttcct gattacagct ctactcattg aagaattttc taaaaaccat
    12841 gagattgatt tgataggatt ttttagaaga cgcttttatc ggattgtgcc acctgtggtt
    12901 ttgatggtct tggtgaccat gccttttact ttcttggttc gccaagacta tgttgctgga
    12961 attggtggcc agattgcgag cgtcttaggc tttatgacca acttctatga actcctaaca
    13021 ggtgggagtt atgaatctca gttcattcct catttgtttg ttcataattg gagtttggca
    13081 gttgaggttc actactatat tctttgggga ttggcagttt ggttcttatc caaacaagct
    13141 aaatcaaatg gtcagttgaa ggggatggtc tttctcttat ctgctgttgc cttcttgatc
    13201 agtttcttct ccatgtttat tggtagtttt ctagtgacct cttattcctc tgtttatttc
    13261 tccagtttaa ctcatgtcta tccattcttt ttgggaagta tgttagcaac tattgtaggc
    13321 gttcgtcaga cgacttccct cgtcaagcag ttggataaaa tctgggattt acgaaagact
    13381 ttggtagttt ttggaggagg ctttggtttc ctagttcttt tgactttctt tgtcaaattc
    13441 acttatcttt ttgcctatct tatcggcttc ttacttgcca gtcttgcagc tcttgccatg
    13501 attctggcgg cgcgtgtctt acatgaaaag acacatcata tacaggagcc gaagattatc
    13561 agctttttag cggatactag ctatgcggtt tatcttttcc attggccttt ctatatcatt
    13621 ttctcacagt tgacatcaaa tcttcttgct gtattactga ctctgatttg ttcttatggc
    13681 tttgccagtc tgtcattcta tgtattggaa ccttggattg caggcaagaa cacacctatt
    13741 gtccaaaccc ttcgtcccct gccttatatt cacgcaattc ttgcagcagg tacaggaatc
    13801 ttgaccatca ttgtctgcac ggtgaccttg ttggcaccac aagtgggagc gtttgagaca
    13861 gacttgactg tcaatggctt gaagcaagct gcaacaaata ttggccagac caaggtgatg
    13921 gcagaacggg cagatgcaaa cagtttggga attgctgatg gcactatgtt aattggtgac
    13981 tcagtggctt taagggcaaa tacagcacta cagacagctc ttcctggagc acagattaac
    14041 gcgcaggtca gcgtaacaac caagaccgca aatgaaatca tgctaaataa tagccagaat
    14101 aaatttttac ctaagacggt ggtcattgcg actggggtaa ataatcctga gaattacaag
    14161 gatgactggg acagtatcgt gaaaaatctt cctaagggac accatatgat tttggtgact
    14221 ccttatgagg gagataagac aaaagagacc tatgccatcg ttgagaaggc tgctgcctat
    14281 atgagagaat tggcagagaa gacaccttac attacgatag cagattggaa tcaagttgcg
    14341 aaagagcatc cagaaatttg ggcaggaaca gaccaggttc atttcgggag tgagagtagc
    14401 actatcgaag caggagcaaa attgtatgca gatacgattg ccacagcttt gcagacagct
    14461 caagacaagc cggttaaatc aaaataactt gtattaaaaa agagaagagt tggagaaatc
    14521 cagctctttt aaaatatctc caaaaaatag gtctatacca tttacaaata aaaaagaaag
    14581 gtttataatg taattgacat aataaattgt agaatcaatc ttttaaggag gttaacatta
    14641 tgcctaacta tattaaagcg gatcagtttt tctacccaca cggagttcgt cgaggtggtt
    14701 acttggaact tgtggacggc aagtttggga aacatgtaga gcagattcct gaaggggctg
    14761 aggtgattga ctatacaggt tatagcattg ccccaggtct tgtggatact catattcatg
    14821 gatatgcagg tgtagatgtg atggacaaca acattgaagg tacattgcat actatgagtg
    14881 aaggacttct tagtaccggt gttaccagtt tcttacccac aactttaaca gccacttatg
    14941 agcaattgct tgcagtcact gaaaatcttg gaaaccatta taaagaagca acaggtgcta
    15001 agattcgtgg gatttattat gaaggtccat atttcacaga aacttttaag ggggcacaaa
    15061 atccaactta tatgagagac ccgggtgttg aggagtttca ttcttggcaa aaagcggcaa
    15121 atggcttgct taataaaatt gcccttgcac cagaacgtga tggggtgggg gactttgttc
    15181 gtacagttac gggcgaaggt gtgacggttg ctcttggaca ttcaaacgcg acttttgatg
    15241 aagccaaaaa agcagtcgat gctggagcga gtgtttgggt gcatgcctac aatggaatgc
    15301 gtgggttgac tcaccgtgaa ttgggtatgg ttggagccat gtaccaattg ccacatacct
    15361 atgcagagtt gatctgtgat ggccaccacg tagatccaaa ggcttgcgaa attcttatca
    15421 aacaaaaagg aacagaaaac atcgctctta tcacagactg tatgacagct gggggattgg
    15481 aagacggaga ttatatgttg ggagaattcc cagttgtcgt tgcaaatgga actgcacgcc
    15541 tcaaatcgac aggtaacttg gcaggttcta tcctcaaact caaagatggt ttgaagaatg
    15601 tggtcgaatg gggaattgcg aatccgcatg aagcagtcat gatggccagc ttcaacccag
    15661 ctaaatccgt tcacatcgat gatgtctgtg gccaaatccg tgaaggctac gacgctgact
    15721 tcatcgtatt agataaagat ttggaattgg tagcaaccta cctagatggc gtaaaacgtt
    15781 atcaagcata agagagaaag cagaagttag agactaactt ctgctttttt atgcagggta
    15841 ctttactggt aaataaaaag ttaaaaaaaa tcacaaaaaa gcttgaagaa acaaagaaaa
    15901 aggcttacaa ttgaactata aatattacaa ataaaaaaac ggaggagtgc tttatgaaag
    15961 cctatactta tgttaaacca ggacttgctt cttttgttga tgtagacaaa ccagttattc
    16021 gcaagccaac agatgctatt gtgcgtattg taaaaaccac tatttgtgga acagacctcc
    16081 atattatcaa aggggatgtt cctacttgcc aaagtggtac cattcttggc cacgaaggga
    16141 ttgggattgt tgaagaagtt ggggaaggag tttccaactt caaaaaaggt gacaaggtct
    16201 tgatttcttg cgtctgtgcc tgtggtaaat gctactactg taaaaaagga atttatgctc
    16261 actgtgaaga cgaagggggc tggattttcg gtcacttgat tgatggtatg caggctgaat
    16321 atctacgtgt ccctcatgca gataatactc tttaccatac tccagaagac ttgtcagatg
    16381 aagctttggt tatgctgtca gacattctgc ctactggata tgaaattggt gtcttaaaag
    16441 ggaaagtaga acctggttgc agcgtagcca ttattggttc aggtccagtt ggattggctg
    16501 ctcttttaac agcccaattc tattcaccag ctaaattgat tatggtggac ttggatgata
    16561 accgtttgga tactgcagta tcctttggtg ctactcataa ggtaaactct tcagaccctg
    16621 aaaaagcgat aaaagaaatt tatgatttga cagatggtcg cggtgtagat gtcgctattg
    16681 aagctgtagg gattcctgca acatttgatt tctgtcaaaa gattatcggt gtagacggaa
    16741 cggttgccaa ctgtggtgtg catggtaaac cagttgaatt cgatttagat aaactttgga
    16801 ttcgcaacat caatgtaaca actggtttgg tatctacaaa tacgactcca caattgttga
    16861 aagcacttga aagtcataag attgaaccag aaaaattggt aactcactat ttcaaactca
    16921 gtgaaattga aaaagcctat gaagtcttca gtaaggcagc agaccaccat gccattaagg
    16981 tcattatcga aaacgatatc tcagaagcct aagtagtaaa aatatttttg tacataagta
    17041 aatagaaatt cagtcatcca tcagatagct ggatttttta tcaaaaaatt aagaaatgag
    17101 catatttctt tccttgtctg gcggaattgg ttataatata cggtacaaag gaatgaatga
    17161 atatgtatcg tgttatagaa atgtacggag attttgaacc gtggtggttc ttagaaggtt
    17221 gggaagaaga tattgtagca agtagaaaat ttgaccagta ttatgatgct ctcaaatact
    17281 acaaaacttg ctggtttaga ttggaacaag aatcccctct ttataaaagt agaagcgact
    17341 tgatgaccat tttttgggac ccggaagacc aacgctggtg tgatgaatgt gatgagtatt
    17401 tacaacaata ccattctttg gctcttttgc aggatgagca ggttatccca gacgaaaaac
    17461 tacgctcagg ctatgaaaaa caaaccagtc aggaaaggaa tcgttcttgc cgtatgaaat
    17521 taaaatagag aaaagtaact tttttggagt tgcttttttt atttttctaa cgctttgcga
    17581 atagtatagg tgaggaggta agtatggttc aagaaattgc acaagaaatc attcgttcgg
    17641 ctcggaaaaa aggggcgcaa gacatttatt ttgtccctaa gttagatgcc tatgagcttc
    17701 atatgagggt aggagacgag cgctgtaaaa ttggtagcta tgattttgaa aagtttgcag
    17761 ccgttatcag tcactttaag tttgtggcgg gtatgaatgt gggagaaaaa agacgtagtc
    17821 aactgggttc ctgtgattat gcctatgacc agaagatagc gtctctacgt ttatctactg
    17881 taggcgatta tcgggggcat gagagtttgg ttatccgttt gttgcacgat gaggagcagg
    17941 acttgcattt ttggtttcag gatattgaag aattaggcaa gcagtacagg caacggggac
    18001 tctatctttt tgctggcccg gttgggagtg gtaagacgac cttgatgcat gaattgtcca
    18061 agtcactctt taaaggacag caagttatgt ccatcgaaga tcctgtcgaa atcaagcagg
    18121 acgacatgct tcagttgcag ttgaacgaag caatcggcct aacctatgaa aatctaatca
    18181 aactttcctt gcgtcatcga ccagatctct tgattatcgg agaaattcgt gacatcgaga
    18241 cggcgcgtgc agtggtcaga gctagtttga caggtgcgac agtcttttca accattcacg
    18301 ccaagagtat ccgaggtgtt tatgagcgtc tgctggagtt gggtgtgagt gaagaagaat
    18361 tggcagttgt tctgcaagga gtctgctacc agagattaat cgggggagga ggaatcgttg
    18421 actttgcaaa cagagattat caagaacacc aagcagccaa gtggaatgag caaattgacc
    18481 agcttcttaa agatggacat atcacaagtc ttcaggctga gacggaaaaa attagctaca
    18541 gctaagcaaa aaaatatcat caccctattt aacaatctct tttctagcgg ttttcatctg
    18601 gtggagacta tctccttttt agataggagt tccttgttgg acaagcagtg tgtgacccag
    18661 atgcgtacag gcttgtctca ggggaaatca ttctcagaaa tgatggaaag tttgggatgt
    18721 tcaagtacca ttgtcactca gttatctcta gctgaagttc atggcaatct tcacctgagt
    18781 ttgggaaaga tagaagaata tctagacaat ctggccaagg tcaagaaaaa gttaattgaa
    18841 gtagcgacct atcctttgat tttgctgggt tttcttctct taattatgct ggggctacgg
    18901 aattacctgc tcccacaact ggatagtagc aatattgcca cccgaattat cggtaatctg
    18961 ccacaaattt ttctaggcat ggtagggctt gtttccgtgc ttgccctttt agcactaact
    19021 ttttataaaa gaagttctaa gatgagtgtc ttttctatct tagcacgcct tccctttatt
    19081 ggaatctttg tgcagaccta cttgacagcc tattatgcac gtgaatgggg gaatatgatt
    19141 tcacagggaa tggagctgac gcagattttt caaatgatgc aggaacaagg ttcccagctc
    19201 tttaaagaaa tcggtcaaga tctggctcaa accctgaaaa atggccgtga attttctcag
    19261 acgataggaa cctatccgtt ctttaggaag gaattgagtc tcatcataga gtatggggaa
    19321 gttaagtcca agctgggtag tgagttggaa atctatgctg aaaaaacttg ggaagccttt
    19381 tttacccgag tcaaccgcac catgaatttg gtgcagccac tggtttttat ctttgtggca
    19441 ctgattatcg ttttacttta tgcggcaatg ctcatgccca tgtatcaaaa tatggaggta
    19501 aatttttaaa atgaaaaaaa tgatgacatt cttgaaaaaa gctaaggtta aagcttttac
    19561 attggtggaa atgttggtgg tcttgctgat tatcagcgtg cttttcttgc tctttgtacc
    19621 taatctgacc aagcaaaaag aagcagtcaa tgacaaagga aaagcagctg ttgttaaggt
    19681 ggtggaaagc caggcagaac tttatagctt agaaaagaat gaagatgcta gcctaagaaa
    19741 gttacaagta gatggacgca tcacggaaga acaggctaaa gcttataaag aataccatga
    19801 taaaaatgga ggagcaaatc gtaaagtcaa tgattaaggc ctttaccatg ctggaaagtc
    19861 tcttggtttt gggtcttgtg agtatccttg ccttgggctt gtccggctct gttcagtcca
    19921 cttttgcggc ggtagaggaa cagattttct ttatggagtt tgaagaactc tatcgggaaa
    19981 cccaaaaacg cagtgtagcc agtcagcaaa agactaatct aaatttagat gggcagacgc
    20041 ttagcaatgg cagtcaaaag ttgacagttc ctaaaggaat tcaggcacca tcaggccaaa
    20101 gtattacatt tgaccgagct gggggcaatt cgtccctggc taaggttgaa tttcagacca
    20161 gtaaaggagc gattcgctat caattatatc taggaaatgg aaaaattaaa cgcattaagg
    20221 aaacaaaaaa ttagggcagt gattttactg gaagcagtag tcgctctagc tatctttgcc
    20281 agcattgcga ccctcctttt gggacaaatt caaaaaaata ggcaagagga agcaaaaatc
    20341 ttgcaaaagg aagaagtctt gagggtagct aagatggccc tgcagacggg gcaaaatcag
    20401 gtaagcatca acggagttga gattcaggta ttttctagtg aaaaaggatt ggaggtctac
    20461 catggttcag aacagttgtt ggcaatcaaa gagccataag gtcaaggctt ttaccttgtt
    20521 agaatcccta cttgccctca ttgtcatcag tgggggatta ctcctttttc aaactatgag
    20581 tcagctcctc atttcagaag ttcgctacca gcaacaaagc gagcaaaagg agtggctctt
    20641 gtttgtggac caacttgagg cagaattaga ccgttcgcag ttcgaaaaag tagaaggcaa
    20701 tcgcctatac atgaagcaag atggcaagga catcgccatc ggtaagtcaa agtcagacga
    20761 ttttcgtaaa accgatgcta gtggacgggg gtatcagcct atggtttatg gcctcaaatc
    20821 agctcagatt acagaggaca atcaactggt tcattttcgt ttccagtttc aaaaaggctt
    20881 agaaagggag ttcatctatc gtgtggaaaa agaaaaaagt taaggcaggt gttctcctct
    20941 acgcagtcac catagcagcc atctttagtc ttttgttgca attttacttg aaccgacaag
    21001 tcgcccacta tcaagactat gctttgaata aagaaaaatt ggttgctttt gcaatggcta
    21061 aacgaaccaa ggataaagcc gagcaagaaa gtggggaaca ggtctttaat ctaggtcagg
    21121 taagctatca aaacaagaaa acaagcttgg tgacgactgt tcgtacgtct aagagccaat
    21181 atgagtttct gtttccttca gtcaaaatca aagaagagaa aagagataaa aaggaagagg
    21241 tagcgactga ttcaagcgaa aaagcggaga aaaaatcaga agagaagcct gaaaagaaag
    21301 agaattcata gtcaattcaa ctataatgcg ttgaatccag aatagtccac tgtagtttct
    21361 agaaaattgc tggaaatgga tgttaagctc caattcattt gtttatatct tatttcagtt
    21421 tactatactt tgtgctaaat taaagatatg aaacatgatt ttaaccacaa agcagaaact
    21481 ttcgattccc ctaaaaatat cttcctcgca aacttggtat gtaaagcagc cgagaaacag
    21541 attgatcttc tatcagacaa agaaatttta gatttcggtg gtggcacggg tctattagct
    21601 ttgcccctag ccaagcaggc taagtcagtt actcttgtag acatttctga gaaaatgttg
    21661 gagtaagctc gtttgaaagc ggagcagcaa gcaatcaaga atatccagtt tttggagcaa
    21721 gatttaccga aaaatccctt ggagaaagag tttgattgcc ttgctgttag tcggcttctt
    21781 catcatatgc ctgatttgga tgcggatctc tcactgtttc atcaacattt gaaggaagat
    21841 aggaaactca tcattgctga ttttaccaag acagaagcta atcatcatgg atttgattta
    21901 gctgaactgg aaaacaagct aattgagcat agtttttcat ctgtgcatag tcagattctc
    21961 tatagcgctg aagacctgtt tcaagggaat cactcagaat tctttttaac agtatcccaa
    22021 aaatcactcg cctagtcagg gagtgatttt tctataagga tggaaaaaag aagggaaatt
    22081 tgataagata ggaatatgga ttttgaaaaa attgaacaag cttatatcta tttactagag
    22141 aatgtccaag tcatccaaag tgatttggcg accaactttt atgacgcctt ggtggagcaa
    22201 aatagcatct atctggatgg tgaaactgag ctaaaccagg tcaaagacaa caatcaggcc
    22261 cttaagcgtt tagcactacg caaagaagaa tggctcaaga cctaccagtt tctcttgatg
    22321 aaggctgggc aaacagaacc cttgcaggcc aatcaccagt ttacgccaga tgctattgcc
    22381 ttacttttgg tatttattgt ggaagagttg tttaaagagg aggaaattac tatcctcgaa
    22441 atgggttctg ggatgggaat tctaggcgct attttcttga cctcgcttac taaaaaggtg
    22501 gattacttgg gaatggaagt ggatgatttg ctgattgatc tggcagctag catggcagat
    22561 gtaattggtt tgcaggctgg ctttgtccaa ggagatgccg ttcgcccaca aatgctcaaa
    22621 gaaagcgatg tggtcatcag tgacttgcct gtcggctatt atcctgatga tgccgttgcg
    22681 tcgcgccatc aagttgcttc tagccaagaa catacttacg cccatcactt gctcatggaa
    22741 caagggctta agtacctcaa gtcagacgga tacgctattt ttctagctcc gagtgatttg
    22801 ttgaccagtc ctcaaagtga tttgttaaaa gaatggctga aagaagaggc gagtctggtt
    22861 gctatgatta gtctgcctga aaatctcttt gctaatgcca aacaatctaa gactattttt
    22921 atcttacaga agaaaaatga aatagcagta gagccttttg tttatccact tgctagcttg
    22981 caagatgcaa gtgttttaat gaaatttaaa gaaaattttc aaaaatggac tcaaggtact
    23041 gaaatataaa atagattttg ttataatagt tgaaaacgct taaaaagggg tatcatgtta
    23101 tgacaaaaac aattgcaatc aatgcaggaa gttcaagttt gaaatggcaa ttatacttaa
    23161 tgccagaaga aaaagtattg gcgaaaggtt tgattgaacg tatcggtttg aaagattcaa
    23221 tttcaactgt aaaatttgac ggccgttctg aacaacaaat tttggatatt gaaaatcata
    23281 tacaagccgt taaaatttta ttggatgact tgattcgttt cgatattatc aaggcttatg
    23341 acgagattac aggtgttgga catcgtgttg ttgctggtgg agaatatttc aaagaatcaa
    23401 cagttgttga gggagatgtt ttagaaaaag ttgaagagtt gagtttgttg gctcctctac
    23461 acaacccggc caatgcagca ggtgttcgtg ccttcaagga attgttgcca gacattacca
    23521 gtgtagttgt ttttgatact tccttccaca caagtatgcc agagaaagct tatcgctacc
    23581 ctctaccaac aaaatattac acagaaaaca aggttcgtaa atacggtgct catggtacaa
    23641 gtcaccagtt tgtagcagga gaagctgcaa aactcttggg acgtccatta gaagacttga
    23701 agttaattac ctgtcatatt ggtaacggag gctcaattac agctgtgaaa gccggcaaat
    23761 ctgtagacac ttctatgggg ttcactcctc ttggtggtat tatgatggga acgcgtacag
    23821 gggatattga tccagctatc attccttatt taatgcaata tacagaggat tttaacacac
    23881 cagaagatat cagtcgtgtt cttaaccgtg aatcaggtct tttgggagtt tctgctaatt
    23941 ctagcgatat gcgcgatata gaagcagctg tagcagaagg gaatcacgag gctagcttgg
    24001 cttatgaaat gtatgttgac cgtatccaaa aacatatcgg tcagtacctt gcagtgctaa
    24061 atggagcaga tgccattgtt ttcacagcag gtgtcggtga aaatgcagag aatttccgtc
    24121 gtgatgtaat ctcagggatt tcgtggtttg gttgtgatgt tgatgatgaa aagaatgtct
    24181 ttggcgttac aggagacatc tcaacagagg cagctaaaat ccgtgtcttg gttattccaa
    24241 cagatgaaga attagtcatt gcccgtgacg ttgaacgctt gaaaaaataa gtgaaactaa
    24301 aaaaatattc aatacaagga gttgggaaag ttatttttcc agcttctttt tctgatgaaa
    24361 ttgtccaaaa ccttgctatg attggctttt ttgaaaaata tggtataata gtagtaattt
    24421 aatagatgga gttgagtttt gaagaaaaac tttcgtgtaa aaagagagaa agattttaag
    24481 gcgattttca aggaggggac aagttttgct aatcgcaaat ttgtggtcta ccaattagaa
    24541 aaccagaaaa accattttcg agtaggtcta tcagttagca aaaaactggg gaatgccgtc
    24601 actagaaatc aaattaagcg acggattcgg catattatcc agaatgcaaa agggagtctg
    24661 gtagaagatg tcgactttgt tgtcattgct cgaaaaggag tcgaaacctt gggatacgca
    24721 gagatggaga aaaatctact ccacgtatta aaattatcaa agatttacca ggaaggaaat
    24781 gggagtgaaa aagaaactaa agttgactag tttgctagga ctgtctctgt taatcatgac
    24841 agcctgtgca actaatgagg taactagcga tattacagcc gattcggctg atttttggag
    24901 taaattggtt tacttctttg cggaaatcat tcgcttttta tcgtttgata ttagtatcgg
    24961 agtggggatt attctcttta cggtcttgat tcgtacagtc ctcttgccag tctttcaggt
    25021 gcaaatggtg gcttctagga aaatgcagga agctcagcca cgcattaagg cgcttcgaga
    25081 acaatatcca ggtcgagata tggaaagcag aaccaaacta gagcaggaaa tgcgtaaagt
    25141 atttaaagaa atgggtgtca gacagtcaga ctctctttgg ccgattttga ttcagatgcc
    25201 ggttattttg gccctgttcc aagccctatc aagagttgac tttttaaaga caggtcattt
    25261 cttatggatt aaccttggta gtgtggatac aacccttgtt cttccgattt tagcagcagt
    25321 attcaccttt ttaagtactt ggttgtccaa caaagctttg tctgagcgaa atggcgctac
    25381 gactgcgatg atgtatggga ttccagtctt gatttttatc tttgcagttt atgcgccagg
    25441 tggagtcgcc ctatactgga cagtgtctaa tgcttatcaa gtcttgcaaa cctatttctt
    25501 gaataatcca ttcaagatta tcgcagagcg cgaggccgta gtacaggcac aaaaagattt
    25561 ggaaaataga aaaagaaaag ccaagaaaaa ggctcagaaa acgaaataaa taaggaggaa
    25621 tctggtaatg gtagtattta caggttcaac tgttgaagaa gcaatccaga aaggattgaa
    25681 agaattagat attccaagaa tgaaggctca tatcaaagtc atttctaggg agaaaaaagg
    25741 ctttcttggt ctatttggta aaaaaccagc ccaagtggat attgaagcga ttagtgaaac
    25801 gactgttgtc aaagcaaatc aacaggtagt aaaaggcgtt ccgaaaaaaa tcaatgattt
    25861 gaacgagcct gtgaagacgg ttagtgaaga aaccgttgac cttggtcatg tggttgatgc
    25921 tattaaaaaa atagaggaag aaggtcaagg tatttctgat gaagtcaagg ctgaaatctt
    25981 aaaacatgaa agacatgcca gcactatctt agaagaaact ggtcacattg agattttaaa
    26041 tgaacttcaa atcgaggaag cgatgaggga agaagcaggc gctgatgacc ttgaaactga
    26101 gcaagatcaa actgaaaatc aagacttgaa agagatgggc ttgaaggtcg agcaaagtta
    26161 tgatattgcc caggtggcta cggatgtgac tgcctatgtt caagcgattg tggatgacat
    26221 ggatgttgag gctacacttt caaatgatta taaccgtcgt agcatcaatc tacaaattga
    26281 caccaacgaa ccaggtcgta ttatcggcta ccatggtaaa gtcttgaagg ccttgcaact
    26341 gttggctcaa aattatcttt acaaccgcta ttccaaaacc ttctacgtta caatcaatgt
    26401 caatgattat gtcgaacacc gtgcagaagt cttgcagacc tatgcgcaaa aattggcgaa
    26461 tcgtgttttg gaagaaggtc gcagtcataa aacagatcca atgtcaaata gcgaacgcaa
    26521 gattatccat cgtattattt cacgtatgga tggcgtgact agttactctg aaggtgatga
    26581 gccaaatcgc tatgttgttg tagatacaga ataagtaaaa tcagggttga cctgattttt
    26641 tgctagttag aggaggttaa actgatgttg aataagataa gagactatct agacttttct
    26701 ggtttgcagt accgtagtcc tgataaagcg ggagcagagc gagagaagat gctggcgttc
    26761 cgccacaaag gacaagaggc ccgaaaggct tttacagaac tggccaaagc ctttcaagca
    26821 agccatccag aatggcaact ccaacagact agtcagtgga tgaatcaggc ccagcgtttg
    26881 agaccacatt tttgggttta tctacagaga gacggacaag tgacagaacc tatgatggcc
    26941 ttacgtttgt atgggacatc tactgacttt ggaatttctt tggaagtcag tttcatcgaa
    27001 cgtaagaagg atgagcaaac actgggcaag cagaccaaag ttttagacat tccaaccgtt
    27061 aaagggattt attatctaac ctactctaat ggtcaaagtc aacggtggga ggcgaatgaa
    27121 gaaaagcgtc gtactttacg cgagaaggtg agaagtcaag aagttcgaaa agttttagtg
    27181 aaggtagatg ttcctatgac agaaaattcg tctgaagaag aaatcgtaga aggcttattg
    27241 aagtcttatt ctaaaattct tccctattat ctagctacga gaaaataaga taatttgtaa
    27301 aacatcataa atcatacagt ccaagagtga acagtccgct gtgtaattct tggtcttttt
    27361 gtttgcgctt tcgcattata taataaactt acaaaaacaa ttcaaaagga gaacaattat
    27421 ggaagtcgtt tcaagtgttc taaattggtt ttctagcaat attttgcaga atcccgcatt
    27481 tttcgtaggt ttattggtgt tgataggata tgcacttttg aaaaaacctg cccatgacgt
    27541 tttttcaggg tttgttaaag caacagtagg gtatatgttg cttaacgtgg gtgctggtgg
    27601 tttggttaca acctttcgtc caatcttagc agctcttaac tacaaattcc aaattggtgc
    27661 agcggttatc gacccttact ttggacttgc tgcagcaaac aacaaaattg cagcagagtt
    27721 tccagatttt gttggaactg caactacagc tctattgatt ggttttggaa taaatatctt
    27781 gctcgtagct cttcgaaaga ttacgaaggt aagaaccctc tttattactg gtcacatcat
    27841 ggtacaacaa gctgcaacag tatcttttat ggttctattc ttagtaccac aattgcgcaa
    27901 tgcttacggt acagcagcga ttggtatcat ctgtggactt tactgggcag ttagttcaaa
    27961 tatgactgtt gaggcaactc aacgcttgac tggtggtggc ggatttgcga ttggtcacca
    28021 acagcaattt gcaatctggt ttgtagataa agtagcagga cgctttggta agaaagaaga
    28081 aagtttagac aatcttaaat tacctaagtt cctctcaatc ttccacgata cagttgttgc
    28141 atctgctacc ttgatgctcg tattcttcgg agccattctt ttaatcttgg gtccagacat
    28201 tatgtctaat aaagaagtca tcacttcagg aactctattc aatcctgcta aacaagattt
    28261 ctttatgtac attatccaaa cagcctttac cttctcagtt tacttgttcg ttttgatgca
    28321 aggtgtccga atgttcgtat ctgagttgac aaacgccttc caaggtattt caaacaaatt
    28381 gttgccaggt tcattcccag cggttgacgt tgcagcttct tatggatttg gttctccaaa
    28441 tgctgtcctg tcaggattta tctttggttt gattggtcaa ttgattacaa ttgttttgct
    28501 catcgtcttt aaaaatccga ttcttattat tacaggattt gtaccagtgt tctttgacaa
    28561 tgcagccatt gcggtctacg ctgataaacg cggcggatgg aaagcggctg ttatcctttc
    28621 ctttatatca ggtgtccttc aagttgctct aggagctctt tgtgtggccc ttctcgattt
    28681 ggcatcttat ggtggctacc atggaaatat cgactttgaa ttcccatggc ttggatttgg
    28741 atatatcttc aaataccttg gtattgttgg ttatgtactt gtgtgtctct tcttgcttgt
    28801 tattcctcaa cttcaatttg ccaaagcaaa agataaagag aaatattaca acggtgaagt
    28861 tcaagaagaa gcttagtatc tagaaaagga gaaataaaat ggttaaagta ttagcagcgt
    28921 gcggaaatgg aatgggttca tcaatggtta tcaagatgaa ggttgaaaat gctctccgta
    28981 agcttaatca aacagatttt acagtcaatt catgcagtgt cggtgaagct aaaggtttag
    29041 cagtaggata tgacatcgta atcgcttctc ttcatttgat tcaagaattg gaagggcgaa
    29101 ctaatgggaa gttaattgga cttgataact tgatggatga taaagaaatc accgaaaaac
    29161 tcagtcaagc actacagtaa aaggttggag ggggctggac agaaactgag agttatcgtt
    29221 tctgtccttc tccctcttta aataaaggag gcagatatga atttaaaaca agctttaatt
    29281 gacaatgact cgatccgact aggtttagag gctaacaatt ggaaagaagc agtcaaggta
    29341 gcagtagatc ccttaattga aagtggggca attttgccag agtattacga tgctatcatt
    29401 gaatcgactg aagagtatgg gccttactat atcttgatgc caggtatggc tatgccccac
    29461 gctagacctg aagctggtgt gcaaagtgat gccttttcat tgattacctt acaaaatcct
    29521 gttgtatttt cagatgggaa agaggtatct gttttgttgg cactagcagc aacaagctca
    29581 aaaattcaca caagtgtagc cattccacaa attattgccc tgtttgaatt agacgattct
    29641 attgcacgtt tacaggcttg ccagactaaa gaagatgtct tggctatgat tgaagaatct
    29701 aaggatagcc cttatctcga aggattggat ttggaaagtt agaaagagga ataaagaaat
    29761 gacaaaaaga atacctaatt tacaagttgc attagaccat tcagacttgc aaggagcgat
    29821 taaagcagct gtttctgttg gtcaggaagt agatattatc gaagctggaa ctgtttgctt
    29881 gcttcaagtt ggaagtgaac tggctgaagt cttgcgtagc cttttcccag ataagattat
    29941 tgtggcagac acaaaatgtg ctgatgctgg tggaacagtt gctaaaaata atgcggttcg
    30001 tggagcagac tggatgactt gtatctgttg tgcaaccatc cctactatgg aagcagctct
    30061 aaaggctatc aagactgaac gaggagaacg aggcgaaatc cagatcgagc tttatggcga
    30121 ttggactttt gaacaagctc agctttggct agatgcaggt atttcacaag ctatttatca
    30181 ccaatctcgt gatgctcttc ttgctggtga aacttggggt gaaaaagacc ttaataaggt
    30241 taaaaaactc attgacatgg gcttccgtgt atctgtaaca ggtggtctag atgtagatac
    30301 tctcaaactc tttgaaggtg ttgatgtctt tacctttatc gcaggtcgtg gaattacaga
    30361 ggctgcggat ccagcaggag cagcgcgtgc cttcaaggat gaaatcaaac gaatttgggg
    30421 gtaaatcatg gtacgtccaa ttggaattta tgaaaaggca accccaacac actgtacttg
    30481 gctagaacgt ttaaattttg ccaaggagtt aggctttgat tttgtcgaga tgtctattga
    30541 cgaacgtgac gagcgtttag caagacttga ctggagtaag gaagaacgct tggaagttgt
    30601 caaagcaatc tatgaaactg gtgttcgtat tccttctatc tgtttttcag gccatcgtcg
    30661 ctacccattg ggttcaaaag atccagttct agaggaaaaa tctctagaac tcatgaaaaa
    30721 atgtatcgaa ttagctcaag acttgggagt tcgtacgatt caattagctg gttacgatgt
    30781 ttactatgag gaaaagtcac cccagacacg ccaacgtttt atcaaaaatt tgagaaaagc
    30841 ctgtgactgg gctgaagaag ctcaggtggt acttgctatt gaaattatgg atgatccttt
    30901 catcaatagc atcgaaaaat atttggctat agaaaaagag attgactctc ccttcctctt
    30961 tgtatatcca gatattggta atgtgtctgc atggcataat gatatctata gtgagtttta
    31021 tcttggtcat catgccatcg cagctctcca tctcaaggat acttatgcag tgacagaaag
    31081 ttcaaagggc cagttccgag atgtaccttt tgggcaaggt tgtgtcaaat gggaagaagc
    31141 tttcgatatt ttaaaggaaa ccaattataa tggacctttc ctaatcgaaa tgtggtctga
    31201 aaattgtgaa acagtagaag aaacacgcgc agccattcaa gaggcgcaag cttttctcta
    31261 tccactcatt aagaaagcag gtttgatgta agatgaatca agtaatcaat gctatgcgta
    31321 aacgagtttg tgatgccaat caatcattgc caaaacatgg acttgtcaaa tttacctggg
    31381 ggaatgtatc tgaagtcaat cgcgaactcg gtgtcattgt tatcaaacca tcaggcgtgg
    31441 attatgacga attgacacct gaaaacatgg tagtgactga tctagatggt aagatcctag
    31501 aaggggattt aagaccatct tccgacctcc caactcatgt gcaattatat aagacttggt
    31561 cagaaattgg tagtgtggtt cacacccatt cgacagaagc tgttggttgg gctcaggcag
    31621 gtcgtgatat tcctttctac ggaacaaccc atgcagatta tttctacggt tcaatccctt
    31681 gcgcccgtag tttgaccaag gacgaagtag aagtggccta tgaaaaagat actggcctgg
    31741 ttatcgtaga agaatttgaa catcgcggac ttaacccggt tgaagtacca ggaattgttg
    31801 tacgcaatca cggtccattc acctggggca aaaatccaga gaatgctgtt tatcactctg
    31861 tcgtactaga ggaagtatca aagatgaatc gctttacaga acaaatcaat ccaagagttg
    31921 gacctgctcc ccagtacata ctagaaaaac actaccaacg taaacatgga ccaaatgctt
    31981 attatggtca aaagtaagaa cgatgaagga ggagaaaaag ataaatttag ctcctctttt
    32041 tacatttgat ttttattgag agtaaagttg gagttgaagt aattttaaaa gattttttag
    32101 aaatagcgct tgatatatat atggtaaaat aaaaagaatt gctgtgatat caatagattt
    32161 gggggatttt ttaatatggt actggataag gcaagttgtg atttgcttca atatttgatg
    32221 gatcaagaaa cgtccaaaac gattatggcg atttcgaaag atttgaaaga gtcaagaagg
    32281 aaaatttatt atcacattga caaaatcaat gctgctctgg gtgacgaggc gcttcacatc
    32341 attagtattc cacgaattgg tattcactta acggaagagc agagagatgc ttgttgtaaa
    32401 ctattatcgg aagtagattc gtacgattat atcatgagtg cgcatgaacg tatgatgata
    32461 atgttactat ggataggtat ttctaaagaa cgtattacga ttgaaaaatt gatagagtta
    32521 acagaggtat ctaggaatac tgttctcaat gatttgaata gcattcgtta tcaactaact
    32581 ttggaacaat atcaggtgac cttgcaagtg agcaagtcac agggatacca ccttcatgcc
    32641 caccctctta ataaaattca gtatcttcaa tcgcttctat atcatatttt tatggaagaa
    32701 aatgccactt ttgtatctat tttagaagat aagatgaaag agaggttaga tgatgagtgt
    32761 ttgctttctg ttgaaatgaa ccaatttttt aaggaacagg ttcctttagt tgaacaagat
    32821 ttagggaaga aaataaacca tcatgaaata acttttatgt tgcaggttct accttatttg
    32881 ctgttaagct gtcataatgt tgaacagtat caagaaagac atcaggatat agagaaagaa
    32941 ttttctttga taagaaaaag aatagagtat caggtgtcta agaaattagg agaacggttg
    33001 tttcaaaagt ttgaaatttc tttgtcagga cttgaagttt ctcttgtagc tgttctcctc
    33061 ctctcctatc gtaaagattt ggatattcat gcagaaagtg atgattttcg gcaattaaaa
    33121 cttgctttag aagaatttat ctggtatttt gaatcacaaa tccgaatgga gattgagaac
    33181 aaggatgatt tgttacgaaa tttgatgatc cactgtaaag ccttgttatt tagaaagact
    33241 tacggtattt tttctaaaaa tcctctaaca aaacaaattc gatccaagta tggagaatta
    33301 tttttagtca ctagaaaatc tgcggaaatt ttagaaggag catggtttat tcggctaaca
    33361 gacgatgata ttgcctattt gacgattcat attggaggat ttttaaaata tacaccatcg
    33421 tctcaaaaaa atatgaaaaa agtttatctc gtttgtgatg aaggtgttgc ggtttcgaga
    33481 cttttgctga aacaatgcaa actttatttt ccaaatgagc aaattgacac tgtatttaca
    33541 acagaacaat ttaagagtgt ggaagatatt gcacaagttg atgtagtgat tactactaat
    33601 gatgatttgg atagcagatt tccgatttta agggttaatc ctatccttga agcagaagat
    33661 attttgaaaa tgctagacta tcttaaacac aatatatttc gtaataagag caaaagtttc
    33721 agtgaaaatc tttctagtct tatttcgtct tatattgtag acagcaagtt ggctagtaag
    33781 ttccaagaag aggttcaaac acttataaat caagaaatag tagttcaagc ttttttggaa
    33841 gatatttgaa ggacagtcca atgatgaaca caaacctgtg tttttcttgg tcttttttag
    33901 tgttttgaag ggtggtatac taatctcaaa gataacaatt atatccaaag gaggcaacat
    33961 atgccaaacg tcaaagaaat tacaagagag tcatggattt tagccacttt cccagagtgg
    34021 ggaacatggt tgaacgaaga aatcgaagaa gaagtcgtac ctgaaggcaa ctttgccatg
    34081 tggtggctag gcaactgtgg tacttggatt aagacaccag ctggtgctaa cgttgtcatg
    34141 gacctttggt caaaccgtgg aaaatcaacc aaaaaagtga aagatatggt tcgtgggcac
    34201 caaatggcaa atatggcagg tgttcgtaag ttgcaaccaa acttgcgtgt tcagccaatg
    34261 gttatcgatc catttgctat caacgaacta gactattact tagtttcaca cttccacagt
    34321 gatcatatcg acccatacac agctgcagca attctcaaca atcctaagtt agagcatgtt
    34381 aagtttatcg gtccttacca ctgtggacga atctgggaag gatggggtgt tccaaaagaa
    34441 cgtatcatcg ttgttaaacc aggtgacact atcgaattaa aagatatgaa gattcatgca
    34501 gtagaatcat ttgaccgtac ttgcttggta actctcccag tgaacggtgc tgatgagaca
    34561 ggcggtgaac ttgctggctt ggctgttaca gatgaagaaa tggctcaaaa ggctgttaac
    34621 tatatctttg aaacaccagg tggaaccatc tatcatggtg cagattctca cttctcaaac
    34681 tattttgcaa aacatggtaa agactttaaa attaatgttg ctttgaataa ctatggtgaa
    34741 aatccggtag gtatccaaga caaaatgaca tctatcgacc ttcttcgtat ggcagaaaat
    34801 ctgcgtacca aagtcattat cccagttcac tatgatatct ggtctaactt catggcttct
    34861 actaatgaga ttctagaact ttggaaaatg cgaaaagatc gcttgcaata cgatttccat
    34921 ccatttatct gggaagttgg cggtaagtac acttatcctc aagatcaaca cttagtagaa
    34981 taccatcatc cacgtggttt tgatgattgt tttgaacaag actctaacat tcaatttaaa
    35041 gctttgctat aatataaaaa tattctttgg aggttatccg tatgttgcat gatacggata
    35101 attttcatat aatagtaaaa tagaatgtgt gattcaataa tcacctcaaa tagaaaggaa
    35161 attctatgtc aaatctatct gttaatgcaa ttcgttttct aggtattgac gccattaata
    35221 aagccaactc aggtcatcca ggtgtggtta tgggagcggc tccgatggct tacagcctct
    35281 ttacaaaaca acttcatatc aatccagctc aaccaaactg gattaaccgc gaccgcttta
    35341 ttctttcagc aggtcatggt tcaatgctcc tttatgctct tcttcacctt tctggttttg
    35401 aagatgtcag catggatgag attaagagtt tccgtcaatg gggctcaaaa acaccaggtc
    35461 acccagaatt tggtcatacg gcagggattg atgctacgac aggtcctcta gggcaaggga
    35521 tttcaactgc tactggtttt gcccaagcag aacgtttctt ggcagccaaa tataaccgtg
    35581 aaggttacaa tatctttgac cactatactt acgttatctg tggagacgga gacttgatgg
    35641 aaggtgtctc aagcgaggca gcttcatacg caggcttgca aaaacttgat aagttggttg
    35701 ttctttatga ttcaaatgat atcaacttgg atggtgagac aaaggattcc tttacagaaa
    35761 gtgttcgtga ccgttacaat gcctacggtt ggcatactgc cttggttgaa aatggaacag
    35821 acttggaagc catccatgct gctatcgaaa cagcaaaagc ttcaggcaag ccatctttga
    35881 ttgaagtgaa gacggttatt ggatacggtt ctccaaacaa acaaggaact aatgctgtac
    35941 acggcgcccc tcttggagca gatgaaactg catcaactcg tcaagccctc ggttgggact
    36001 acgaaccatt tgaaattcca gaacaagtat atgctgattt caaagaacat gttgcagacc
    36061 gtggcgcatc agtttatcaa gcttggacta aattagttgc agattataaa gaagctcatc
    36121 cagaactggc tgcagaagta gaagccatca tcgacggacg tgatccagtc gaagtgactc
    36181 cagcagactt cccagcttta gaaaatggtt tttctcaagc aactcgtaat tcaagtcaag
    36241 atgccttgaa tgttgtggca gctaaattac caacctttct aggtggatca gctgaccttg
    36301 ctcactcaaa catgacttat atcaagacgg atggacttca agacgatgcc aatcgcttga
    36361 atcgtaacat tcagtttggt gttcgtgaat ttgcaatggg aacaatcttg aacgggatgg
    36421 cccttcatgg tggacttcgt gtatacggtg gaactttctt cgtcttctct gactatgtga
    36481 aggcagctgt ccgcttgtca gccttacaag gacttcctgt gacttatgtc tttacccatg
    36541 attcaatcgc agttggggaa gatggtccga ctcatgaacc agttgagcat ttagcaggtc
    36601 ttcgtgctat gccaaatcta aatgttttcc gtccagcaga tgcgcgtgaa actcaagcag
    36661 cttggtacct tgcagtgaca agtgagaaaa caccaactgc ccttgtcttg acacgtcaaa
    36721 acttgactgt tgaagatgga acagacttcg acaaggttgc taaaggtgct tatgttgtat
    36781 atgaaaatgc agccgacttt gataccatct tgattgcgac aggttcagag gttaatcttg
    36841 ctgtctcagc tgctaaagaa ttggctagtc aaggcgaaaa aatccgcgta gtcagcatgc
    36901 catctacaga tgtctttgat aaacaagatg cagcttacaa ggaagaaatt cttccaaatg
    36961 cagtccgccg tcgtgttgca gtcgaaatgg gtgcaagtca aaactggtac aaatatgttg
    37021 gtctcgatgg tgccgttcta ggtattgata ccttcggagc ctctgcccca gcaccaaaag
    37081 tattggcaga atatggcttt actgtagaaa atcttgtaaa aattgttcga aacttgaaat
    37141 aatcctaaaa atcagggcgt aagctctggt ttttcttacc agaaaagtaa ggtacaatct
    37201 tgtaaaagta gctgaaattt gatatagtag tcctatgtaa aagacaaagg agaaaacaat
    37261 gaatccaaat attacttttt taatcatgct tgtaggtatg atggccttga tgttctttat
    37321 gcaacgttct caaaagaaac aagctcaaaa gcgtatggaa agcttaaata aactacaaaa
    37381 aggctatgaa gtgattacaa tcggtggact ttatggaaca gtcgatgaag tagatacgga
    37441 gaagggaaca atagttcttg acgtagatgg agtttacttg acttttgaac tagctgctat
    37501 caagacagta ttaccgctga aagaaacagc ttcactagaa ggcgcaattg aaaaataaga
    37561 cgggatcacg aactcccgtt tttctataaa agaaaggaaa tgggatgaaa aaattagtct
    37621 ttgtctgtct gggaaatatt tgccgtagcc ctatggccga gtttgttatg aaatcaatga
    37681 cagataacta cgaaatccaa agtcgagcaa cttcctcttg ggaacatggc aatccgattc
    37741 ataaggggac tcagggaatt tttcaagagt atgagattcc ttatgacaag aacaagacat
    37801 cgcttcagat tagtaaggaa gattttgaag cctttgatta tattatcgga atggacgctt
    37861 caaatatttc tgacttacgt cagatgtgtc cagtagactg tcaagataag atttactcat
    37921 tttcatctga aagtgttcca gacccttggt atacaggaga ttttgaagaa acctatcgac
    37981 gtgttcaaga gggctgtcaa gcttggttag aacgtttaga aaaggagagt taaggtggaa
    38041 aatcttacga atttttacga aaagtatcgt gtctatctga ctcgtccacg attagagctt
    38101 ttggcagtag ttaccattgt tttctgtgct gtactcgtct tttttctaaa tattccagga
    38161 aaaggtgtct taaaactcga taatggaacg attgtttatg atggcagtct tgtccgtggt
    38221 aaaatgaatg gtcaaggtac cattaccttc caaaatggag accaatatac aggtggcttc
    38281 aacaatggag ccttcaacgg aaaaggtacc tttcaatcta aagaaggctg gacctacgaa
    38341 ggtgattttg taaatggtca ggctgaagga aaagggaaac taacaacaga acaagaagtc
    38401 gtttatgaag gaacttttaa acaaggcgtt tttcaacaaa aataaagcct ccttatccaa
    38461 aggaggtatt attagaacca caaggtaagc gcttacctgt aaatcccttt ctttccaaat
    38521 ccctcttcca agcaagtttg tgaaataaaa aatatttgaa ataaatttca caaactttaa
    38581 agataaaacc tgataagaaa agaaaatgag aaaagtttca caagagttta aaaattcttt
    38641 gtgaaatgtt tatgaaactg tttacaaagt tgaaataatg cgttataata aacttgtgaa
    38701 aaaattaaca aaggatatcg ttccttgaaa gctatggagg aaaatatggc tgataaaaaa
    38761 actgtgacac cagaggaaaa gaaactcgtt gctgaaaaac acgtagatga gttggttcaa
    38821 aaagctctag ttgcccttga agaaatgcgt aaattggatc aagaacaagt tgactacatc
    38881 gttgccaaag catcagtagc agctttggat gcccacggag aattggcttt acatgccttt
    38941 gaagaaacag gacgtggtgt atttgaagac aaagcaacta agaacttgtt tgcctgtgaa
    39001 cacgtagtaa acaacatgcg ccacactaag acagttggcg ttatcgaaga agacgatgta
    39061 acaggattga ctcttattgc tgaaccagtt ggtgttgttt gtggtattac tccaacaaca
    39121 aacccaacat caacagcaat cttcaaatca ttgatttcat tgaagacacg taacccaatc
    39181 gtctttgcct tccatccatc agcacaagaa tcatctgctc atgcagctcg tatcgtccgc
    39241 gatgcagcta tcgcagctgg tgctcctgaa aactgtgtgc aatggattac tcaaccatct
    39301 atggaagcaa caagtgccct tatgaaccac gaaggtgttg cgacaatcct tgcaacaggt
    39361 ggtaatgcca tggttaaggc ggcttattca tgtggtaaac cagctcttgg ggtaggtgcc
    39421 ggaaacgttc cagcttatgt tgaaaaatca gcaaacattc gtcaagcagc acacgatatc
    39481 gtcatgtcta aatcatttga taacggtatg gtctgtgcat ctgaacaagc agttatcatt
    39541 gataaagaaa tttacgatga atttgtagca gagttcaaat cttaccacac ttactttgta
    39601 aacaaaaaag aaaaagctct tcttgaagag ttctgcttcg gcgtcaaagc aaacagcaaa
    39661 aactgtgctg gtgcaaaatt gaacgctgac atcgttggta aaccagcaac ttggattgca
    39721 gaacaagcag gatttacagt tccagaagga acaaacattc ttgctgcaga atgtaaagaa
    39781 gttggcgaaa atgagccatt gactcgtgaa aaattgtcac cagttattgc agttttgaaa
    39841 tctgaaagcc gtgaagatgg tattactaag gctcgtcaaa tggttgaatt taacggtctt
    39901 ggacactcag cagctatcca cacagctgac gaagaattga ctaaagaatt tggtaaagct
    39961 gttaaagcta ttcgtgttat ctgtaactca ccttctactt ttggtggtat cggggacgtt
    40021 tacaatgcct tcttgccatc attgacactt ggatgtggtt cttacggacg caactcagtt
    40081 ggggataacg ttagtgccat taacctcttg aatatcaaaa aagtcggaag acggagaaat
    40141 aacatgcaat ggatgaaact tccttcaaaa acatactttg aacgtgattc aattcaatac
    40201 cttcaaaaat gtcgtgacgt tgaacgtgtc atgatcgtta ctgaccatgc catggtagag
    40261 cttggtttcc ttgatcgtat catcgaacaa ctggaccttc gtcgcaataa ggttgtttac
    40321 caaatctttg cggatgtaga accggatcca gatatcacaa ctgtaaaccg tggtactgag
    40381 attatgcgtg ccttcaaacc agataccatc atcgcactcg gtggtgggtc tccaatggat
    40441 gctgccaaag taatgtggct cttctacgag caaccagaag tggacttccg tgaccttgtc
    40501 caaaaattca tggatatccg taaacgtgcc ttcaagttcc cattgcttgg taagaagact
    40561 aaattcatcg cgattccaac tacatctggt acaggatctg aagtaacacc atttgccgtt
    40621 atctctgata aagcaaacaa ccgtaaatac ccaatcgctg actactcatt gacaccaact
    40681 gtggcaatcg tagatcctgc tttggtattg acagttccag gatttgttgc tgctgatact
    40741 ggtatggacg tattgactca cgcgacagaa gcatacgtat cacaaatggc tagtgactac
    40801 actgatggtt tagcacttca agccattaaa ttggtctttg aaaatctcga aagctcagtt
    40861 aagaatgcag acttccactc acgtgagaaa atgcataacg cttcaacaat cgctggtatg
    40921 gcctttgcca atgccttcct aggtatttct cactcaatgg cccataagat tggtgcgcaa
    40981 ttccacacaa tccacggtcg tacaaatgcc atcttgcttc catacgttat ccgttacaac
    41041 ggtacacgtc cagctaagac agcaacatgg cctaagtaca actactaccg tgcagatgaa
    41101 aaataccaag atatcgcacg catgcttgga cttccagctt ctactccaga agaaggggtt
    41161 gaatcttacg caaaagctgt ttacgaactc ggtgaacgta ttgggatcca aatgaatttt
    41221 agagaccaag gaattgacga aaaagaatgg aaagaacatt ctcgtgaatt agccttcctg
    41281 gcttatgaag accaatgttc accagctaac ccacgtcttc caatggtaga ccatatgcaa
    41341 gaaatcatcg aagatgcata ctatggctac aaagaaagac caggacgccg taaataattg
    41401 tttatcagtc tagaagcaag acaaaaactc aatttgaggg aaagatccag taatttttct
    41461 atgataaaag gcatcctatc aaggtttttg aacacctgat aggatgcctt tttatgatat
    41521 tgaggccttt ttgccctttt tgaaaaacta gaatagaaac aaaatatata atagattgaa
    41581 actagaatag tacacatctg cttctaaaac attgttagaa ttcgatttga ctgtcctgat
    41641 cgatttgtcc tgttcttatt tcattttaat atataaaaaa tatagtatag tagactgaat
    41701 ctaaaatagt acgaaacaat tgctaaaaca tttatagaaa ttaattttac tttcctgata
    41761 gagttgttca catcttattt caattcacta tagtttaatt taagagtagt atttactaag
    41821 gcccaattaa aatcaaagag caaacgagaa aacgatgaca aggtgtgttg ctttttgatt
    41881 tctaaagagt ataatgatag atctctataa aataagtgcg aaggaaatga gcttttataa
    41941 tcctttcgtt ttaaaatact atctcagata ttcttatatc gacaagaagt ttttgagtca
    42001 ttccctcatc atacatatta aataaatagt ggctcattca atttttcact agaataataa
    42061 gctagtatag taaactgaaa taagatataa acaaataaat tggagcttaa catccatttc
    42121 cagcaatttt ttagaaacta cagtggacta ttctagattc aacatattat aaaaactaga
    42181 gtaaaagaaa aggattggat cttgtgtaat gcaggatcca atcctttcaa tcattttgtc
    42241 caacttttgg aggttcctac aatgtagccg tcattaataa agacagatgg gaacgacagt
    42301 gttcctattt attttgatag agatcgatga attctttaga tagcaactga ataatctccg
    42361 ttgaagccat ttggtcttct gcatgcataa atagcaagga gaatcctatt ttttctccag
    42421 tagcttcttt ttgtatgaga ttagagtgaa tcttgtgcac ttctactaag gagtcttccg
    42481 cttcttcaac tttaattttc gcttctttta aatttcctgc cttagctagt tggatggctt
    42541 caataaagga tgatttggct gctccactat tggcaatgag ctgaaaacag atatattcca
    42601 tttcttctgt catcttattt ctcctatcca tgcaagtgct tgttccagaa cttttgctcc
    42661 attcatcatt ccgtaatccc gcatatcaat ggtatctaca gggatatttc ctgcaatttc
    42721 tttcacagca agtaactcat aacgaatttg tggcccaatt agaatgacat ctgcttcatg
    42781 gatattcttt ttcgcttctg tcattgattt tgcttggata gaaatttcaa tcccacgttc
    42841 agtcgcactt tgttgcattt ttttaacaag catacttgtc gacattcccg cattacatac
    42901 taataaaatt tgtttcataa tcttaacctt ccatttcttg ttcaacaact ttgtcattaa
    42961 ctttgataaa tggaatgtat agaagaactc caagtgcaaa gatgatgaat tgaactagaa
    43021 ctgctctcac gtcccctgct gttgctaacc atgcatttaa gaatactggt gtagtccaag
    43081 gaacttgtat aaatgcagga ctcatgaatc ctgtaactgt tgctaagtag ctgattaaaa
    43141 taccaaggac tggaactgtg ataaatggaa tagctaatga aatgttataa acgattgggt
    43201 aaccgaataa tactggttca ttgatattga agataccagg tccaaaagat aatttagcca
    43261 cgtttttaga gacagcattg cgactcacta agaatgttgc tattaataaa cataatgtag
    43321 atccactacc acccattaaa gcgaatgttt gtatttgtga taagttgatg atgtgtggaa
    43381 tggcttgtcc attatttgct gcagtgatgt tttcagtaat gttaattaat agtaatggtt
    43441 ctaagatggc actgtaaata actgcttggt gaataccaaa tagccataac atatttccta
    43501 aagagtaaat aataatgacc ccgattaagc ttgtaccaat atgacgaatt ggttcttgaa
    43561 taaagattgt aatgattgag attaagttca ttccagttat attgaataat aatgctgaaa
    43621 caatcccaaa taaggagatg acagtcatga ctggaagtaa tacgctaaat gatctactaa
    43681 cagctggtgg aatattttca ccaaggttca tttgtaaagc tttaacgttt gataattcaa
    43741 tgaataattc tgttgcaata atcgctacga taaccccggc gaacattgcg cctgtacctg
    43801 tgttgttgaa tgaaagaaca cctgaaatgt ttaccgcatc ttttgctccg tcaggaacta
    43861 cagaaactgt atttggcatc atcacaatta aagaaactaa tgatagcatt gatgctgcta
    43921 acgggttttc gaaatctctg tttttagcta agaaataacc aaccattaca gcaataatca
    43981 tacctgaaat acttaaagta ccgtttgcaa ttgttattcc ccaatattgg aatcttgtta
    44041 atgtatcccc ttggaaaatc cacttaaata ccgtgttgtt caaaagaacg attaaacctg
    44101 ccaaaatata taatggcatt actgttacga atgcatctct tagggttttt aaatgaattt
    44161 ggttccctag tttaccagca aaggtggcaa attgatctat aaattttgag tttttcatct
    44221 gaatatctcc tctctttact cctcaatttc tacttcaaaa ccgttattgt cacttacttt
    44281 gcgataccat cttcctgagc tcttgatggt tctcttttgc gtttctaaat caacggagat
    44341 aaatccgtaa cgattcttat atgcattatt ccaagaccag caatcaaatg cggtccaagc
    44401 gtggtatcca aaacagtgac ttccctcttc aatggcttta tgtagccatc ttaaatgttc
    44461 ttcataaaat tcaatacgat acacgtcatc gataactcca ttttcaccga taaaccgtgc
    44521 ttcgttttca acacccattc cgttttcact gataaaccat ggaatattat catattcttc
    44581 cttcacaatc atagcaatat cataaatggc tttcggaaaa atttcccaac cacgatatgg
    44641 attcatgcga cgctccggcc attcatactc tttgaagtat tggtctggca tccagggcgt
    44701 ctgatattcc tcaggatttg cttgtgcttg aacacgtttt ggatggtagt agtttactcc
    44761 aagaaaatca accgtatttg atttcatcag ttgaagctct ttttcggtat gactccataa
    44821 cacgccatct ctctctagct gttttaccaa tctttctggg aaagttcctt taacagctgg
    44881 attcaagaag actttgttaa agaagtcatc tgtaaatcga cttgcttcta agtcttctgg
    44941 agaattactt cttggataag caggtgtcaa gtttaaaata atcccaatct ttccatcaag
    45001 tcctaatgag cgatatagtt gaatcacttt tgcactagca aggtttagat tatagatgac
    45061 ttgtacggcc tcttttccct ttccttttag atttggataa tggaaagcat ataagtatcc
    45121 tgcttctgga atgaccattg gctcattgaa agttgtccag taatgaacct tatctccaaa
    45181 gcatgtgaaa gcagtcttgg caaacttcac gaataactcc actacatgtt tgctttccca
    45241 accaccgtat ttttgaagaa gttccactgg taaatcaaaa tgatgtaaat tcatcacaag
    45301 atccatctgg ttctttttag cttcttcaat gatggcattg tagaaagcaa taccttttgg
    45361 atcaggctca cctgtctcta aattcttgat gagtcgactc cattggatgg aagtgcggaa
    45421 agaattaact ccaatttcct tcatcaagtg gaaatcttcg gtgtaagtat gaaaaaagtt
    45481 actggctaca agaggtccga cattatcgaa aaaatcttct ggatgcgttt tgaaccagta
    45541 gtccatcaca ttttcatgta cttttccata ttgaccttct gtctgaggtc cgctagaagc
    45601 agctccccac caaaacagat taggaaatac taactttttt ttcatgctca acctcctttc
    45661 tattattcta tacataaagt atagcataac tttaaaattt gtctagacat ttttaaaaat
    45721 tgttgataca tatcttgtgt ttgcctcatt tcttgaactt tgttatacta ctattagaat
    45781 attatagaga gaaccagatt aaatgagtac aaaatattta tttatttaca atgagattcg
    45841 tgaaaagatt ctttgtaata aatataccat gaacgaacaa ttgcctgatg aaatgacatt
    45901 agctaaacag tttgcctgta gtcgaatgac gatcaaaaaa gctttagact tgttagtttc
    45961 tgagggctta atttttagaa aacgtgggca gggaaccttt gttctctctc gtggcagctc
    46021 aaaaagaaaa ttaatcgttc cagaaagaga tatccgggga ctgacaaaaa tatctgaaga
    46081 tgctcattct acaattgact cgaggattat tcacttcaaa ttagaatttg caaatgaatt
    46141 tttagcagaa aaactacagg tcgctttgca gagtccagtt tataatattt accgcctgcg
    46201 tattattgac ggtaaacctt atgttctgga acaaacttat atgagtaccg atgttattcc
    46261 aggtattact gaagatattt tacaaaaatc gatttacaat tacattgaag gaaagttagg
    46321 attgcatatt gccagtgcta caaaaatctt acgagcttct tctagttcag aaaatgagca
    46381 acattacttg cagctccttc caacggaacc ggtatttgaa gtagaacaag tggcttattt
    46441 ggataatgga actccgtttg agtactcgat tagtcgtcat cgctatgatt tatttgaatt
    46501 taattctttt gcattacgac attcctccta ggagaaaatg tgaaaatgaa gccaatcttt
    46561 tacaggctct agtttaagaa aaatttaaaa cagggcaaga aggtcccatc tatgcttaaa
    46621 tggtttctct tttctaaata agatgacttt aaaagagtga tcgttttatc catcatgttg
    46681 aaaaatatct tcgtatagct tatagagtag gtactgaaat tgttcacctg atatacttct
    46741 tatagttatt tagttttaaa tagtgtttca aacattctta cactgacgag aagtttttga
    46801 gtcttttctt gtaacacata tagtatattg aggttagaat agtagactgt gacttctaaa
    46861 aaattgctag aaatgaattt caatctccca atttatttgt tcatatcttc ttttaatata
    46921 ttaaataaat tctgaatcat aatcatttaa aaaaattt
//
LOCUS       DAVLTT010000011        46858 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLTT010000011 DAVLTT010000000
VERSION     DAVLTT010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46858
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.011"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            128..6562
                     /locus_tag="VYN15_000664"
     CDS             128..6562
                     /locus_tag="VYN15_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV1452023.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAMETSQDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKE
                     ENSNKSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKELSSLKNTKVLYT
                     YDRIFNGGAIETTQDNLNKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSI
                     NAPFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDK
                     IPHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNA
                     QIFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRA
                     LRKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQ
                     TVEFDKVNIGGQSFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLD
                     LRGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEG
                     TKSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNV
                     GDEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVI
                     NGKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLEKPVLKNLKGDDKIDLTSLTKIAL
                     QNTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYG
                     SISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDG
                     KQIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFES
                     VEEMEALSSNGKKTDFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDG
                     KPKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAESTS
                     GSKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVV
                     SREHFIRGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPAT
                     KIRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLI
                     TKDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTY
                     AGEGQGRNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEK
                     GMISYYLVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIE
                     GKSLFNIHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIA
                     YDDGTDLEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIE
                     IKATKYDFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKE
                     TKSEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSNLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYINGKEYTSFNDIKQIIDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
     gene            7188..7664
                     /locus_tag="VYN15_000665"
     CDS             7188..7664
                     /locus_tag="VYN15_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1452024.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            7702..8007
                     /locus_tag="VYN15_000666"
     CDS             7702..8007
                     /locus_tag="VYN15_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1452025.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            8055..9530
                     /locus_tag="VYN15_000667"
     CDS             8055..9530
                     /locus_tag="VYN15_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV1452026.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            9553..9630
                     /locus_tag="VYN15_000668"
                     /pseudo
     CDS             9553..9630
                     /locus_tag="VYN15_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            9880..16581
                     /locus_tag="VYN15_000669"
     CDS             9880..16581
                     /locus_tag="VYN15_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV1452027.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVEEYEVDKWEIAEEDKVKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKAVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTANVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPASEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(16829..17685)
                     /locus_tag="VYN15_000670"
                     /pseudo
     CDS             complement(16829..17685)
                     /locus_tag="VYN15_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125496.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(17895..18254)
                     /locus_tag="VYN15_000671"
     CDS             complement(17895..18254)
                     /locus_tag="VYN15_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV1452028.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            18277..18855
                     /locus_tag="VYN15_000672"
     CDS             18277..18855
                     /locus_tag="VYN15_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846832.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEV1452029.1"
                     /translation="METRNRGIYRKVRLLRLWVIFVIMKVIKSYNTLNDYYRKLFGEK
                     TFKVPIDAGFDCPNRDGTVAHGGCTFCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKW
                     PDVQKYLVYFQNFTNTHEKVEVIRERYEQAINEPGVVGINIGTRPDCLPDETIEYLAE
                     LSECMHVTVELGLQTTYEATSDLINRAHSYEL"
     gene            18874..19302
                     /locus_tag="VYN15_000673"
     CDS             18874..19302
                     /locus_tag="VYN15_000673"
                     /inference="COORDINATES: protein motif:HMM:NF027524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452030.1"
                     /translation="MRKYPKIEIVSHLINGLPGETHEMMVENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLMSQDEYVRVICDQLEIIPKHIVIHRITGDAPRDMLIG
                     PMWSLKKWEVLNSIEMEMRRRGSVQGCKVVKQEFENEKTT"
     gene            19286..19843
                     /locus_tag="VYN15_000674"
     CDS             19286..19843
                     /locus_tag="VYN15_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1452031.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            19836..20090
                     /locus_tag="VYN15_000675"
     CDS             19836..20090
                     /locus_tag="VYN15_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452032.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            20102..22156
                     /locus_tag="VYN15_000676"
     CDS             20102..22156
                     /locus_tag="VYN15_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV1452033.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFVSLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            22335..23195
                     /locus_tag="VYN15_000677"
     CDS             22335..23195
                     /locus_tag="VYN15_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV1452034.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            23406..24116
                     /gene="ccdA2"
                     /locus_tag="VYN15_000678"
     CDS             23406..24116
                     /gene="ccdA2"
                     /locus_tag="VYN15_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1452035.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQTS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            24136..24702
                     /locus_tag="VYN15_000679"
     CDS             24136..24702
                     /locus_tag="VYN15_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV1452036.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            24713..25825
                     /gene="msrB"
                     /locus_tag="VYN15_000680"
     CDS             24713..25825
                     /gene="msrB"
                     /locus_tag="VYN15_000680"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1452037.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            26093..26830
                     /locus_tag="VYN15_000681"
     CDS             26093..26830
                     /locus_tag="VYN15_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1452038.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            26827..28518
                     /locus_tag="VYN15_000682"
     CDS             26827..28518
                     /locus_tag="VYN15_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1452039.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMIAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            28634..29197
                     /locus_tag="VYN15_000683"
     CDS             28634..29197
                     /locus_tag="VYN15_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV1452040.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKS"
     gene            29219..34687
                     /locus_tag="VYN15_000684"
     CDS             29219..34687
                     /locus_tag="VYN15_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1452041.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAEAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAQPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKSAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQEDNSKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETVNQPVEQPKVETPAVEKQTEPTEEPKVEVTTVETREEVIPFETKE
                     QEDDTLKRGTRQVVQKGVEGKKQITETYKTIRGEKTNEAPIVKETVIEQPQDEIIKKG
                     TKGLEKPTLQWANTEKDVLKKSATASYTLTKPAGVEIKSIKLALKDKDGQLVKEVTVA
                     ENNLNATLDKLKYYQGYTLSTTMVYDRGEGEETEKLEDKQIQLDLKKVEIKNIKETSL
                     MNVDAEGNETDKSLLSEKPTDVSQLYLRVTTHDNKVTRLAVSSVEEVVVDGKTLYKVV
                     AKAPDLVQRRADDTLSEEYVHYFEKQLPKVNNVYYNFNELVKDMQANPTGEFKLGADL
                     NAANVKPNGKSYVTKPFKGKLLSNDGGRFTIHNIERPLFANIEGGKIHDINLANVNIN
                     MPWADKVAPIANVIKNNATIENVKVTGNVLGKDWVSGFIDKIDGSGKLINVAFIGNVT
                     SVGTGGNFLTGIVGENWKGYVERAYVDAHIKGKRAKAAGIAYWSQNQGNNFTIGSEGA
                     IKKSVVKGTIDVEKPIEVGGAVGSFTYHGSIEDTVSMMKVKNGEIFYGSKDIDDDPYY
                     TGNHVNRNYVVIGVSEGTSTYRYSNQHNRIKPITQSEADVKIAETAITADKFTITDPI
                     VNKLNALTTRDNEYRTTQDYKATREQAYRNIEKLQPFYNKEWIVNQGNKLVEGSNLLT
                     KEVLSVTGIKSGQFVTDLSDIDKIMIHYSDGAKEELNVTRQESNVQQVREYSITDLDI
                     LYTPNMVEKDRAQLMTDVKSKLSSVELESDGVRQLLVKRDTKKDANANSVGRQNGYIR
                     DLFLEESFSEVKANLDKLVKQILENEDHQLNDNELAERALLKKVEDNKAKIMMGLAYL
                     NQYYAFKYDELSIKDIMMFKPDFYGKTASVIDRLINIGSAENNLKGDRTQDAYRGIIS
                     GATGKGSLHDFLTYNMKLFTNETDINVWFKKAIEKNAYVVEQPSTNPAFANKKYRLYE
                     GINNGQHGRMILPLLNLKNAHLFMISTYNTISFSSFEKYGKDTDEKREKFKSEINKRA
                     KEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHNSPNGWASRHGHIDGKPDYAP
                     IREFFGRINKYHGYKYGYGAYAYIFAAPQPMDAVYFVMTDLISDFGTSAFTHETTHVN
                     DRMAYYGGHWHREGTDLEAFAQGMLQTPSVSNPNGEYGALGLNMAYERQNDGNQWYNT
                     NPNDLTTRAEIDNYMKGFNDTLMLLDYLEGEAVLNKANQDLNNAWFKKVDKQLRGAST
                     KNQYDKVRDLTADEKNITLNSVDDLVDNNFMTKHGPGNNVYDPTGFGTAYVTVPITAG
                     IYGGNTSEGAPGSMSFKHNTFRMWGYYGYEKGFLNYASNMLKNESRQAGHNTLGDDFI
                     IKKVSDNKFSTLEDWKKAYFKEVVDKAKEGFNPVTIDSTTYSSYDDLKNAFAAAVEKD
                     KATLKNGSVKSDNTVALKEKIYKKLLQQTDSFKTSIFR"
     gene            34748..36469
                     /gene="pabB"
                     /locus_tag="VYN15_000685"
     CDS             34748..36469
                     /gene="pabB"
                     /locus_tag="VYN15_000685"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV1452042.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLTVHKVPLLGEYLLYFTVHDRVETSPVPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRSHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            36470..37087
                     /locus_tag="VYN15_000686"
     CDS             36470..37087
                     /locus_tag="VYN15_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1452043.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFFELLK"
     gene            37137..37895
                     /locus_tag="VYN15_000687"
                     /pseudo
     CDS             37137..37895
                     /locus_tag="VYN15_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            38022..38981
                     /locus_tag="VYN15_000688"
     CDS             38022..38981
                     /locus_tag="VYN15_000688"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV1452044.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            39078..39917
                     /locus_tag="VYN15_000689"
     CDS             39078..39917
                     /locus_tag="VYN15_000689"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV1452045.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTSFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(39965..40135)
                     /locus_tag="VYN15_000690"
     CDS             complement(39965..40135)
                     /locus_tag="VYN15_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV1452046.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            40256..41140
                     /gene="miaA"
                     /locus_tag="VYN15_000691"
     CDS             40256..41140
                     /gene="miaA"
                     /locus_tag="VYN15_000691"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV1452047.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            41133..42371
                     /gene="hflX"
                     /locus_tag="VYN15_000692"
     CDS             41133..42371
                     /gene="hflX"
                     /locus_tag="VYN15_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV1452048.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     NYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            42364..42987
                     /locus_tag="VYN15_000693"
     CDS             42364..42987
                     /locus_tag="VYN15_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV1452049.1"
                     /translation="MTDIKALALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            43002..43931
                     /locus_tag="VYN15_000694"
     CDS             43002..43931
                     /locus_tag="VYN15_000694"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV1452050.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            43952..44707
                     /locus_tag="VYN15_000695"
     CDS             43952..44707
                     /locus_tag="VYN15_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV1452051.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(44761..45669)
                     /locus_tag="VYN15_000696"
     CDS             complement(44761..45669)
                     /locus_tag="VYN15_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1452052.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            45733..46002
                     /locus_tag="VYN15_000697"
     CDS             45733..46002
                     /locus_tag="VYN15_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV1452053.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            46002..46382
                     /locus_tag="VYN15_000698"
     CDS             46002..46382
                     /locus_tag="VYN15_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1452054.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            46471..46698
                     /locus_tag="VYN15_000699"
     CDS             46471..46698
                     /locus_tag="VYN15_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452055.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
BASE COUNT        15051 a         8369 c        10193 g        13245 t
ORIGIN      
        1 taacaattat atataaatgt actactctat ttcctagata atacttagta aaacttttta
       61 taacaaaggc tagcaaagtt aaagtttatt atctattgga agttatataa atatgtaagg
      121 aattaaaatg aaaaaaagta cagtattgtc attaaccaca gctgcagtta ttttagcagc
      181 ctatgcccct aatgaggtag tcttagcaga cacatctagc tctgaagatg ctttaagcat
      241 ctctgataaa gaaaaagtag tagtagataa ggaaacagaa aataaagaga aacataaaga
      301 tattcataat gctatggaaa cttcacagga tactgaagaa aagaaaacaa caattattga
      361 ggaaaaagaa gttgttagta aaaatcctgt gatagacact aaaactagca atgaagaagc
      421 aaaaatcaaa gaagaaaatt ccaataaatc ccaaggagat catacggact catttgtgaa
      481 taaaaacaca gaaaatccca aaaaagaaga taaagttgtc tatattgctg aatttaaaga
      541 taaagaatct ggagaaaaag caatcaagga gctatccagt cttaagaata caaaagtttt
      601 atatacttat gatagaattt ttaacggtgg tgctattgaa acaactcaag ataatctgaa
      661 taaaattaaa caaatagaag gtattacatc ggttgaaagg gcacaaaaag tccaacccat
      721 gatgaatcat gccagaaagg aaattggagt tgaggaagct attgattacc taaagtctat
      781 caatgctccg tttgggaaaa attttgatgg tagaggtatg gtcatttcaa atatcgatac
      841 tggaacagat tataggcata aggctatgag aatcgatgat gatgccaaag cctcaatgag
      901 atttaaaaaa gaagacttaa aaggaactga taaaaattat tggttgagtg ataaaatccc
      961 tcatgcgttc aattattata atggtggcaa aatcactgta gaaaaatatg atgatggaag
     1021 ggattatttt gacccacatg ggatgcatat tgcagggatt cttgctggaa atgatactga
     1081 acaagatatc aaaaacttta acggcataga tggaattgcg cctaatgcac aaattttctc
     1141 ttataaaatg tattctgacg caggatctgg gtttgcgggt gatgaaacaa tgtttcatgc
     1201 tattgaagat tctatcaaac acaacgttga tgttgtttcg gtatcatctg gttttacagg
     1261 aacaggtctt gtaggtgaga aatattggca agctattagg gcattaagaa aagcaggcat
     1321 tccaatggtt gtcgctacgg gtaactatgc gacttctgct tcaagttctt catgggattt
     1381 agtagcaaat aatcatctga aaatgaccga cactggaaat gtaacacgaa ctgcagcaca
     1441 tgaagatgcg atagcggtcg cttctgctaa aaatcaaaca gttgagtttg ataaggttaa
     1501 cattggagga caaagtttta aatacagaaa tataggggcc tttttcgata agaataaaat
     1561 cacaacaaat gaagatggaa caaaagctcc tagtaaatta aaatttgtat atataggcaa
     1621 ggggcaagac caagatttga taggtttgga tcttaggggc aaaattgcag taatggatag
     1681 aatttataca aaggatttaa aaaatgcttt taaaaaagct atggataagg gtgcacgcgc
     1741 cattatggtt gtaaatactg taaattacta caatagagat aattggacag agcttccagc
     1801 tatgggatat gaagcggatg aaggtactaa aagtcaagtg ttttcaattt caggagatga
     1861 tggtgtaaag ctatggaaca tgattaatcc tgataaaaaa actgaagtca aaagaaataa
     1921 taaagaagat tttaaagata aattggagca atactatcca attgatatgg aaagttttaa
     1981 ttccaacaaa ccgaatgtag gtgacgaaaa agagattgac tttaagtttg cacctgacac
     2041 agacaaagaa ctctataaag aagatatcat cgttccagca ggatccacat cttgggggcc
     2101 aagaatagat ttacttttaa aacccgatgt ttcagcacct ggtaaaaata ttaaatccac
     2161 gcttaatgtt attaatggca aatcaactta tggctatatg tccggaacta gtatggcgac
     2221 tccaatcgta gcagcttcta ctgttttgat tcgaccaaaa ttgaaggaaa tgcttgaaaa
     2281 acccgtatta aaaaatctta aaggtgatga taaaatagac cttacaagtc ttacaaaaat
     2341 agccctacaa aatactgcaa gacctatgat ggatgcaact tcttggaaag aaaaaagtca
     2401 atactttgca tcacctagac agcagggggc ggggctaatt aatgtggcca acgctttgag
     2461 aaatgaagtt gtagcgactt tcaaaaacac ggattctaaa ggtttggtaa attcatatgg
     2521 ttccatttct cttaaagaaa taaaaggtga taaaaaatac tttacaatta agcttcacaa
     2581 tacatccaac aggcctttaa cctttaaagt ttcagcatca gcggtgacta cagattctct
     2641 aactgacaga ctaaaactgg atgaaacata taaagatgaa aaatctccag atggtaagca
     2701 aattgttcca gaaattcatc cagaaaaagt caaaggggca aatattacat ttgagcatga
     2761 cactttcact ataggggcaa attctagctt tgatttaaat gcggttataa atgttgggga
     2821 ggctaaaaat aaaaataaat ttgtagaatc atttattcat tttgagtcag tagaagaaat
     2881 ggaagcatta agctccaatg gcaagaaaac cgacttccaa ccatctttat caatgcccct
     2941 aatgggattt gctgggaatt ggaaccacga accaatcctt gataaatggg cttgggaaga
     3001 aggatcaaaa tcaaaaacaa tggaaggtta tgatgatgac ggtaaaccaa aaattccagg
     3061 aaccttaaat aaggggattg gtggagaaca tggtatagat aaatttaatc cagcaggagt
     3121 tatccaaaat agaaaagata aaaatagaac atctctagat caagatccag acttatttgc
     3181 ctttaacaac caaggtgttc atgcagaatc cactagtggt tctaagattg ctaacattta
     3241 tcctttagat tcaaatggaa atcctcaaga tgctcaacta gaaagaggac taactccatc
     3301 tccacttgtt ctaagaagtg cagaagaagg actaatttca attgtaaaca ccaacaaaga
     3361 aggagaaaac caaaaagacc ttaaagttgt atcaagagag cacttcataa gaggaattct
     3421 aaattctaag ggaaatgacg ctaagggtat caaatcatcc aaactaaaag tttggggtga
     3481 cttgaaatgg gatggactca tctataaccc aagaggtaga gaagaaaatg ccccagaaag
     3541 taaggataac caagatccag ctactaagat acgaggacaa tttgaaccga ttgcggaagg
     3601 tcaatatttc tataaattta aatatagatt aactaaagat tacccatggc aggtttccta
     3661 tattcctgta aaaattgata acacagcccc taagattgtt tcggttgatt tttcaaatcc
     3721 tgaaaaaatt aagctaatca caaaggatac ttatcacaag gtaaaagatc aatacaagaa
     3781 tgaaacttta tttgctagag atcaaaaaga acatcctgaa aaatttgatg agattgcaaa
     3841 tgaggtgtgg tatgcaggag ctgctcttgt taatgaagat ggagaggttg agaaaaatct
     3901 tgaagtaact tatgcaggtg agggtcaagg aagaaatagg aagcttgata aagatgggaa
     3961 tactatctat gaaattagcg gagcaggaga tctaagagga aaaatcatcg aagtaatcgc
     4021 cctagatgga gcaagcaact ttaccaaaat ccataggatt aaatttgcta atcaagctga
     4081 tgaaaaaggg atgatttcct attatctagt agatcctgat caggattcat ctaaatacca
     4141 aaagcttggc gaaattcctg aatctaaatt taagaattta aaaaatgtta aagatgatag
     4201 cctaaacaaa gagacagctg aggtggaaaa taacctttta gtagataatc agtctatcga
     4261 aggaaaatct ctctttaata ttcataaaac tatttcaaca attagagact ttgaaaataa
     4321 agacctaaag aaactcatta aaaagaaata taagcaagaa gacgactttg taaatggtgg
     4381 aacaagaaca gtagagcgtg attataaata cgatgataaa ggaaatataa tagcctacga
     4441 tgatgggact gatctagaat atgaaactga gaaacttgac gaaatcaaat caaaaattta
     4501 tggtgttcta agtccgtcta aagatggaca ctttgaaatt cttggaaaga taagtaatgt
     4561 ttctaaaaat gccaaggtat attatgggaa taactataaa tctatagaaa tcaaagcgac
     4621 caagtatgat ttccactcaa aaacgatgac atttgatcta tacgctaata ttaatgatat
     4681 tgtggatgga ttagcttttg caggagatat gagattattt gttaaagata atgatcagaa
     4741 aaaagctgaa attaaaatta gaatgcctga aaaaattaag gaaactaaat cagaatatcc
     4801 ctatgtatca agttatggga atgtcataga attaggggaa ggagatcttt caaaaaacaa
     4861 accagacaat ttaactaaaa tggaatctgg taaaatctat tctgattcag aaaaacaaca
     4921 atatctgtta aaggataaca tcattctaag aaaaggctat gcactaaaag tgactaccta
     4981 taatcctgga aaaacggata tgttagaagg aaatggagtc tatagcaagg aagatatagc
     5041 aaaaatacaa aaggccaatc ctaatctaag agtcctttca gaaacaacaa tttatgctga
     5101 tagtagaaat gttgaagatg gaagaagtac ccaagctgta ttaatgtcgg ctttggacgg
     5161 ctttaacatt ataaggtatc aagtgtttac atttaaaatg aacgataaag gggaagctat
     5221 cgataaagac ggaaatcttg tgacagattc ttctaaactt gtattatttg gtaaggatga
     5281 taaagaatac actggagagg ataagtccaa tgtagaagct ataaaagaag atggctccat
     5341 gttatttatt gataccaaac cagtaaacct ttcaatggat aagaactact ttaatccatc
     5401 taaatctaat aaaatttatg tacgaaatcc agaattttat ttaagaggta agatttctga
     5461 taagggtggt tttaactggg aattgagagt taatgaatcg gttgtagata attatttaat
     5521 ctacggagat ttacacattg ataacactag agattttaat attaagctga atgttaaaga
     5581 cggtgacatc atggactggg gaatgaaaga ctataaagca aacggatttc cagataaggt
     5641 aacagatatg gatggaaatg tttatcttca aactggctat agcaatttga atgctaaagc
     5701 agttggagtc cactatcagt ttttatatga taatgttaaa cccgaagtaa acattgatcc
     5761 taagggaaat actagtatcg aatatgctga tggaaaatct gtagtcttta acatcaatga
     5821 taaaagaaat aatggattcg atggtgagat tcaagaacaa catatttata taaatggaaa
     5881 agaatataca tcatttaatg atattaaaca aataatagac aagacactaa acattaagat
     5941 tgttgtaaaa gattttgcaa gaaatacaac cgtaaaagaa ttcattttaa ataaagatac
     6001 gggagaggta agtgaattaa aacctcatag ggtaactgtg accattcaaa atggaaaaga
     6061 aatgagttca acgatagtgt cggaagaaga ttttatttta cctgtttata agggtgaatt
     6121 agaaaaagga taccaatttg atggttggga aatttctggt ttcgaaggta aaaaagacgc
     6181 tggctatgtt attaatctat caaaagatac ctttataaaa cctgtattca agaaaataga
     6241 ggagaaaaag gaggaagaaa ataaacctac ttttgatgta tcgaaaaaga aagataaccc
     6301 acaagtaaac catagtcaat taaatgaaag tcacagaaaa gaggatttac aaagagaaga
     6361 tcattcacaa aaatctgatt caactaagga tgttacagct acagttcttg ataaaaacaa
     6421 tatcagtagt aaatcaacta ctaacaatcc taataagttg ccaaaaactg gaacagcaag
     6481 cggagcccag acactattag ctgccggaat aatgtttata gtaggaattt ttcttggatt
     6541 gaagaaaaaa aatcaagatt aggacaaaag ctatagaaaa aaatggttta tgtactgaga
     6601 ttagatagtg aggtgatgac atagttttgt gaaaacagcc atttataatt caattattta
     6661 gtttacttca ctattgatac tatttggagt tattaatgga cttagtttag ataactaatg
     6721 aattgattga aagggttagt attgacaata ttggtcatat tgattagaaa atagagtcta
     6781 tcaaaattta aaggctaata gaggtgatga gacaatttca aggaattaag tagcgtttgg
     6841 ttgcttaatt cctttttatt tggaaggaag tttttcgtaa ccgcccaata acgaagtcta
     6901 ttggacggtt acgatatgat cactgacttc gtcagttcta tctacaacct aaaaacagtg
     6961 ttttgaacaa cctgcggcta gctttctagt ttgctctttg attttcattg aatattagaa
     7021 cagcaaaaat gcttggagta tttgtttgtg tgtttgtttt tatataacaa actataaaca
     7081 aaacaaaaat ataaaaaaag agacaaaaaa gaacagaaag taattgacaa cggtttcata
     7141 tagtgttata cttatggcat aaagttaatg gaaagaaggg aaaacttatg gtattagatt
     7201 atttctttga caaaaacctt gtgttttgct tagaagcgga taatcaagaa caactctttg
     7261 atcaggttgc aactttattg gaagaacgag aaattgtcac tccaacttat cgtgaagcct
     7321 tgatcacgcg tgaaaagtca tttccaactg gtttagatat ggaatttcta ggaaaggact
     7381 tgccaaatgt agcgattcct catacagata ttgttcataa tctagctgag aaagtggtgg
     7441 ttgttcgatt agaaaaacca gtaacttttc acaatatgat agctcctgat aaggaagtag
     7501 aagtatcctt gctcttcttt atcatcaata actcaagttc aagtcaaaca aatattctgg
     7561 ctcagttgat ggactttttc acaggaaatg gacatcttga agacctatca aaaatttccg
     7621 aaccagaaaa actttatgct tacattgctg aagcaaccgc ttaatcttgt ctattaaaaa
     7681 ataaaatcgg aggaaatcca aatgattaaa attcttgctg cctgcggtgc aggtgttaac
     7741 tcaagtcacc aaattaaaag tgctctagaa gaagaacttt caaaccgtgg ttatgatgtt
     7801 cactgtgatg cagtcatggt gaaagatgta aacgaagacc ttatgaaagg ttacgatatc
     7861 tttacaccaa tcgctgcaac agaccttggt tttgaaccag gtatcccagt tatcgaagct
     7921 ggaccaatct tattccgtat cccagcaatg agcgctccag tatttgacaa tattgaagca
     7981 gctattaaag aacacggatt aagctaattc taatttgtta acattcatat aacataaaaa
     8041 agggaggaac tgttatggat gcaatctttg acctaatcgg aaaggttttc aatcccatct
     8101 tagaaatggg tggacctgtc atcatgttaa tcattttgac agtattggct ttactttttg
     8161 gagtgaaatt ctccaaagcg cttgaaggtg gtatcaaact tgccatcgct cttacaggta
     8221 tcggtgctat catcggtatg ctaaatggtg ctttctcagc atcacttgca aaattcgttg
     8281 aaaacactgg tatacaattg agtattaccg acgttggttg ggcaccactc gcaacaatca
     8341 cttggggttc tgcttggaca ctatacttct tgctcatcat gttgattgtc aacgtagtga
     8401 tgcttgctat gaagaaaacc gatacacttg atgtcgatat ctttgatatc tggcacttgt
     8461 ctatcacagg tctcttgatt aaatggtatg ctgataacaa tggtgtgagt caaggggttt
     8521 cactctttat tgctacagca gctatcgtcc ttgtcggtgt gttgaaaatt atcaactctg
     8581 acttgatgaa acctacattt gatgaccttc ttaacgcccc aagttcatca ccaatgacat
     8641 caactcacat gaactacatg atgaacccag ttatcatggt tttggataag atttttgaaa
     8701 aattcttccc aggccttgat aaatatgact ttgatgctgc taaattgaac aagaaaatcg
     8761 gtttctgggg atctaaattc ttcatcggtt tcatccttgg tatcgttatt ggtattatgg
     8821 gaactccaca tccaattgca ggtgttgcag atgcagataa atggcgtctt gttatcaaag
     8881 gatggttgtc tcttggtttg actgccggtg tatctttgga actcttctca cttatcggtt
     8941 catggttcat cgcagccgta gaaccactat cacaaggtat tacaaacgtt gctactaaac
     9001 gtcttcaagg acgtaaattc aatatcggtc ttgactggcc attcatcgct ggtcgtgctg
     9061 aaatctgggc ttgtgccaac gtacttgcac caatcatgtt gattgaagca gtgcttcttt
     9121 caaaagttgg aaatggtatc ttgccacttg caggtatcat cgctatgggt gttactccag
     9181 cactcttggt tgtaactcgt ggtaaattgc tccgtatgat tatcttcgga acactcttgt
     9241 tgccactctt ccttctttca ggtacactta ttgcaccatt tgcaacagaa cttgctaaag
     9301 gtgtaggtgc cttcccagaa ggtgtgagcc aaactcaatt gattactcac tctactcttg
     9361 aaggaccaat cgaaaaactt cttggttgga caattggtaa cactacaact ggtgatatca
     9421 aagcaatcct tggtgcagta gccttccttg tattctatat cggtatcttt gcttggtaca
     9481 gaaaacaaat gatcaaacgt aacgaagagt acgcagcaaa agcaaaataa tgcgctccta
     9541 taaaatataa actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca
     9601 aaacacagtt ttgaggttgt agataagact gacgaagtca gctcaaaaca tggttttgag
     9661 gttgtagatg aaactgacga agtcagctca aaacatggtt ttgaggttgt agatgaaact
     9721 gacgaagtca gtaatcatat ctacggcaag gcgacactga cgaagtttga attggatttt
     9781 cgcagagtgt aaattgttga aactaggttg tcataccatg tataccactt gggctttagt
     9841 agtagctaac tgcactaaat ataatataag gagggtttta tggggaaagg ccattggaat
     9901 cggaaaagag tttatagcat tcgtaagttt gctgtgggag cttgctcagt aatgattggg
     9961 acttgtgcag ttctattagg aggaaatata gctggagaat ctgtagttta tgcggatgaa
    10021 acacttatta ctcatactgc tgagaaacct aaagaggaaa aaatgatagt agaagaaaag
    10081 gctgataaag ctttggaaac taaaaatgta gttgaaagga cagaacaaag tgaacctagt
    10141 tcaactgagg ctattgcatc tgagaagaaa gaagatgaag ccgtaactcc aaaagaggaa
    10201 aaagtgtctg ctaaaccgga agaaaaagct ccaaggatag aatcacaagc ttcaagtcaa
    10261 gaaaaaccgc tcaaggaaga tgctaaagct gtaacaaatg aagaagtgaa tcaaatgatt
    10321 gaagacagga aagtggattt taatcaaaat tggtacttta aactcaatgc aaattctaag
    10381 gaagccatta aacctgatgc agacgtatct acgtggaaaa aattagattt accgtatgac
    10441 tggagtatct ttaacgattt cgatcatgaa tctcctgcac aaaatgaagg tggacagctc
    10501 aacggtgggg aagcttggta tcgcaagact ttcaaactag atgaaaaaga cctcaagaaa
    10561 aatgttcgcc ttacttttga tggcgtctat atggattctc aagtttatgt caatggtcag
    10621 ttagtggggc attatccaaa tggttataac cagttctcat acgatatcac caaatacctt
    10681 cacaaagatg gtcgtgagaa tgtgattgct gtccatgcag tcaacaaaca gccaagtagc
    10741 cgttggtatt caggaagtgg tatctatcgt gatgtgactt tacaagtgac agataaggtg
    10801 catgttgaga aaaatgggac aactatttta acaccaaaac ttgaagaaca acaacatggc
    10861 aaggttgaaa ctcatgtgac cagcaaaatc gtcaatacgg acgacaaaga ccatgaactt
    10921 gtagccgaat atcaaatcgt tgaacgaggt ggtcatgctg taacaggctt agttcgtaca
    10981 gcgagtcgta ccttaaaagc acatgaatca acaagcctag atgcgatttt agaagttgaa
    11041 agaccaaaac tctggaccgt tttaaatgac aaacctgcct tgtacgaatt gattacgcgt
    11101 gtttaccgtg acggtcaatt ggttgatgct aagaaggatt tgtttggtta ccgttactat
    11161 cactggactc caaatgaagg tttctctttg aatggtgaac gtattaaatt ccatggagta
    11221 tccttgcacc acgaccatgg ggcgcttgga gcagaagaaa actataaagc agaatatcgc
    11281 cgtctcaaac aaatgaagga gatgggagtt aactccatcc gtacaaccca caaccctgct
    11341 agtgagcaaa ccttgcaaat cgcagcagaa ctaggtttac tcgttcagga agaggccttt
    11401 gatacgtggt atggtggcaa gaaaccttat gactatggac gtttctttga aaaagatgcc
    11461 actcacccag aagctcgaaa aggtgaaaaa tggtctgatt ttgacctacg taccatggtc
    11521 gaaagaggca aaaacaaccc tgctatcttc atgtggtcaa ttggtaatga aataggtgaa
    11581 gctaatggtg atgcccactc tttagcaact gttaaacgtt tggttaaggt tatcaaggat
    11641 gttgataaga ctcgctatgt taccatggga gcagataaat tccgtttcgg taatggtagc
    11701 ggagggcatg agaaaattgc tgatgaactc gatgctgttg gatttaacta ttctgaagat
    11761 aattacaaag cccttagagc taagcatcca aaatggttga tttatggatc agaaacatct
    11821 tcagctaccc gtacacgtgg aagttactat cgccctgaac gtgaattgaa acatagcaat
    11881 ggacctgagc gtaattatga acagtcagat tatggaaatg atcgtgtggg ttgggggaaa
    11941 acagcaaccg cttcatggac ttttgaccgt gacaacgctg gctatgctgg acagtttatc
    12001 tggacaggta cggactatat tggtgaacct acaccatggc acaaccaaaa tcaaactcct
    12061 gttaagagct cttactttgg tatcgtagat acagccggca ttccaaaaca tgacttctat
    12121 ctctaccaaa gccaatgggt ttctgttaag aagaaaccga tggtacacct tcttcctcac
    12181 tggaactggg aaaacaaaga attagcatcc aaagtagctg actcagaagg taagattcca
    12241 gttcgtgctt attcgaatgc ttctagtgta gaattgttct tgaatggaaa atctcttggt
    12301 cttaagactt tcaataaaaa acaaaccagc gatgggcgga cttaccaaga aggtgcaaat
    12361 gctaatgaac tttatcttga atggaaagtt gcctatcaac caggtacctt ggaagcaatt
    12421 gctcgtgatg aatctggcaa ggaaattgct cgagataaga ttacgactgc tggtaagcca
    12481 gcggcagttc gtcttattaa ggaagaccat gcgattgcag cagatggaaa agacttgact
    12541 tacatctact atgaaattgt tgacagccag gggaatgtgg ttccaactgc taataatctg
    12601 gttcgcttcc aattgcatgg ccaaggtcaa ctggtcggtg tagataacgg agaacaagcc
    12661 agccgtgaac gctataaggc gcaagcagat ggttcttgga ttcgtaaagc atttaatggt
    12721 aaaggtgttg ccattgtcaa atcaactgaa caagcaggga aattcaccct tactgcccac
    12781 tctgatctct tgaaatcgaa ccaagtcact gtctttactg gtaagaaaga aggacaagag
    12841 aagactgttt tggggacaga agtgccaaaa gtacagacca ttattggaga ggcacctgaa
    12901 atgcctacca ctgttccgtt tgtatacagt gatggtagcc gtgcagaacg tcctgtaacc
    12961 tggtcttcag tagatgtgag caagcctggt attgtaacgg tgaaaggtat ggctgacgga
    13021 cgagaagtag aagctcgtgt agaagtgatt gctcttaaat cagagctacc agttgtgaaa
    13081 cgtattgctc caaatactga cttgaattct gtagacaaat ctgtttccta tgttttgact
    13141 gatggaagtg ttgaagagta tgaagtggac aagtgggaga ttgccgaaga agataaagtt
    13201 aagttagcaa ttccaggttc tcgtattcaa gcgaccggtt atttagaagg tcaaccaatt
    13261 catgcaaccc ttgtggtaga agaaggcaat cctgcggcac ctgcagtacc aactgtaacg
    13321 gttggtggtg aagctgtcac aggtcttact agtcaaaaac caatgcaata ccgcactctt
    13381 gcttatggag ctaagttgcc agaagtcaca gcaagtgcta aaaatgcagc tgttacagtt
    13441 cttcaagcaa gcgcagcaaa cggcatgcgt gcgagcatct ttattcagcc taaagatggt
    13501 ggccctcttc aaacctatgc aattcaattc cttgaagaag cgccaaaaat tgctcacttg
    13561 agcttgcaag tggaaaaagc tgacagtctc aaagaagacc aaactgtcaa attgtcggtt
    13621 cgagctcact atcaagatgg aacgcaagct gtattaccag ctgataaagt aaccttctct
    13681 acaagtggtg aaggggaagt cgcaattcgt aaaggaatgc ttgagttgca taagccagga
    13741 gcagtcactc tgaacgctga atatgaggga gctaaaggcc aagttgaact cactatccaa
    13801 gccaatactg agaagaagat tgcgcaatcc atccgtcctg taaatgtagt gacagatttg
    13861 catcaggaac caagtcttcc agcaacagta acagttgagt atgacaaagg tttccctaaa
    13921 actcataaag tcacttggca agctattccg aaagaaaaac tagactccta tcaaacattt
    13981 gaagtactag gtaaagttga aggaattgac cttgaagcgc gtgcaaaagt ctctgtagaa
    14041 ggtatcgttt cagttgaaga agtcagtgtg acaactccaa tcgcagaagc accacaatta
    14101 ccagaaagtg ttcggacata tgattcaaat ggtcacgttt catcagctaa ggttgcatgg
    14161 gatgcgattc gtccagagca atacgctaag gaaggtgtct ttacagttaa tggtcgctta
    14221 gaaggtacgc aattaacaac taaacttcat gttcgcgtat ctgctcaaac tgagcaaggt
    14281 gcaaacattt ctgaccaatg gaccggttca gaattgccac ttgcctttgc ttcagattca
    14341 aatccaagcg acccagtttc aaatgttaat gacaagctca tttcctacaa taaccaacca
    14401 gccaatcgtt ggacaaactg gaatcgtagt aatccagaag cttcagtcgg tgttctgttt
    14461 ggagattcag gtatcttgag caaacgctcc gttgataatc taagtgtcgg attccacgaa
    14521 gaccatggag ttggtgcacc gaagtcttat gtgattgagt attatgttgg taaggctgtc
    14581 ccaacagctc ctaaaaaccc tagttttgtt ggtaatgagg accatgtctt taatgattct
    14641 gccaactgga aaccagttac taatctaaaa gcccctgctc aactcaaggc tggagaaatg
    14701 aaccacttta gctttgataa agttgaaacc tatgctattc gtattcgcat ggttaaagca
    14761 gataacaagc gtggaacgtc tatcacagag gtacaaatct ttgcgaaaca agttgcggca
    14821 gccaagcaag gacaaacaag aatccaagtt gacggcaaag acttagcaaa cttcaaccct
    14881 gatttgacag actactacct tgagtctgta gatggaaaag ttccggcagt cacagcaaat
    14941 gttagcaaca atggtctcgc taccgtcgtt ccaagcgttc gtgaaggtga gccagttcgt
    15001 gtcatcgcga aagctgaaaa tggcgacatt ttaggagaat accgtctgca cttcactaag
    15061 gataagaact tactttctca taaaccagtt gctgcggtta aacaagctcg cttgctacaa
    15121 gtaggtcaag cacttgaatt gccgactaag gttccagttt acttcacagg taaagacggc
    15181 tacgaaacaa aaaacctgac agttgaatgg gaagaagttc cagcggaaaa tctgataaaa
    15241 gcaggtcaat ttaccgttcg aggccatgtc cttggtagtg atcttgttgc tgaggtcact
    15301 gtacgagtga cagacaaact aggcgaagct ctttcagata accctaacta tgatgaaaac
    15361 agtaaccagg cctttgcttc agcaaccaat gatattgaca aaaactctca tgaccgcgtt
    15421 gactatctca atgacggaga tcattcagaa aatcgtcgtt ggacaaactg gtctccaaca
    15481 ccatcttcta atccagaagt atcagcgggt gtgatcttcc gtgaaaatgg taagattgta
    15541 gaacggactg ttgctcaagc caaacttcac ttctttgcag atagtggtac ggatgcacca
    15601 actaaactcg ttttagaacg ctatgtcggt ccagagtttg aagtgccaac ctactattca
    15661 aactaccaag cctacgacgc agaccatcca ttcaacaatc cagaaaattg ggaagctgtg
    15721 ccttatcgtg cggataaaga catcgcagct ggtgatgaaa tcaacgtaac atttaaagct
    15781 gtcaaagcca aagctatgag atggcgtatg gagcgtaaag cagataagag cggtgttgcg
    15841 atgattgaga tgaccttcct tgcaccaagt gaattgcctc aagaaagcac gcaatcgaag
    15901 attcttgtag atggaaaaga acttgctgat ttcgctgaaa atcgtcaaga ctatcaaatt
    15961 acctataaag gtcaacggcc aaaagtctca gttgaagaaa acaatcaagt agcttcaact
    16021 gtggtagata gtggagaaga tagccttcca gtacttgttc gcctcgtttc agaaagtgga
    16081 aaacaagtca aggaataccg tatccagttg actaaggaaa aaccagcttc tgagaagaca
    16141 gttgctgctg tacaagaaga tcttccaaaa ctcgaatttg ttgaaaaaga tttggcctac
    16201 aagacagttg agaaaaaaga ttcaacactg tatctaggtg aaactcgtgt agaacaagaa
    16261 ggaaaaactg gtaaagaacg tatctttaca gcgattaatc ctgatggaag taaggaagaa
    16321 aaactccgtg aagtggtaga agctccgaca gaccgcatcg tcttggttgg aaccaaacca
    16381 gtagctcaag aagctaaaaa accacaagtg tcagaaaaag cagatacaaa accaattgat
    16441 tcaagtgaag ctagtcaaac taataaagcc cagttaccaa atacaggtag tgcggcaagc
    16501 caagcagcag tagcagcagg tttagctctt ctaggtttga gtgcaggatt agtagttact
    16561 aaaggtaaaa aagaagacta gaaattttga taccttcttt atcattaaag accaaagaaa
    16621 aactcttgtc ctaaatagaa gataaagagt ctggaacaaa atagttctca accacaaaaa
    16681 agctagatat ttccaattgc ggaactctag ctttttaatt ttgagtcgtt ctcttattgt
    16741 atagtagatt gaaactagag tagtacactt ctacttctaa aacattgtta gaaatcgatt
    16801 tgactgtcct tatcgatttg tcctgttctt atttcatttc actatgtttt aggaggttat
    16861 tggccataag taccaatccc atgtcaattc tcacttgact cttgcctctc agattacatc
    16921 tcttgtaacc caaacaagcc tttatctgcc caaagacagg ttctacatca atcttgcgtt
    16981 gagcgaaaat ctgtctatct tggggagata aaagcgcctg acattcttta gctttcaagt
    17041 tttgatagcg ttcgttcata tacaatccct tttgaggggc tgattcaggt tcatcagcgt
    17101 agtaaacctt gatttcctgt tgaaagtctg tctgtgtttt ctggtacttg atatggtgaa
    17161 aacgatagca ccagccatca ggatgtatgt agctatcctc cttgtcatta tagtgccaat
    17221 tcgctaagtt tttagctgac tgtttatacc ctctcttttg tttcttatca aacatggcat
    17281 atttaatcag aaggggagtg atttcttctt gaaaatagac ttgtatctgt tcttgaagtt
    17341 tggcggagaa tttctctgtc gttttcttcc acacaaaact atacttgttg gcattggctt
    17401 caatcttagt tccgtcaata aacaaacaat ctaaggtcac taactcttcc atttttcaat
    17461 ttttcgacca gagaaaatcc cttgtgaata ggcaaataga agagtagata caagcatttt
    17521 agggtgataa gacgggcgac caaaggcatg atagaaggcg tagaagtgac gttcctccaa
    17581 ggtattcacc actttttcaa tagtaaagac gagatggtct tgtggtaaga aggaactgat
    17641 ttctagtggt aaagttgttt gatttgtgtt atagtgaata tgcatgggat agtctttcta
    17701 aatggtttat taagcaattc tattttacca agactatcgt aaccatgcaa aaaagcaacg
    17761 gcaaatccgt tgcctttttg gatataagag actattgtcc cagactcttt tctttgtata
    17821 aaattgtata gtgttattgt ctatactatt ttgtagagaa agcaaaaatc cctagaaaat
    17881 gcttagggat tcgactattt cattaagaac aattcaacaa tcatttctat atacatgata
    17941 agggttaata agaatcctgc acgccagaag aatttgatga atttaggata gtaaaagctg
    18001 cgttttttta aaaggaagaa aaagacgaga ataatggcta ggaacgagag ggctagcccc
    18061 agtctaggga ggaaattatg ggtaaaggtt ttagctgtaa tcaagtaata ctcaaatacc
    18121 aagactggaa aagccaaatc cgcaaagttt cgtcctagtt tttttaatct aaaaagtttg
    18181 gttaggataa tgcagacgac taaggtcagt atcaataata aaatagatgc taatttcatt
    18241 aaaatcatac ccatattgta tcataaaaaa aggctaatgg aaacgagaaa cagaggaatt
    18301 tataggaaag tcaggctttt gagattgtgg gtgatttttg ttataatgaa agttataaaa
    18361 tcttataata ccttgaatga ttattatcga aaactgtttg gagaaaagac ttttaaagtc
    18421 cctattgatg cgggatttga ctgtcccaat cgtgatggaa ctgtggctca tggaggctgt
    18481 actttttgta cggtttcagg ttctggagat gctattgtag ccccagatgc gcctatccgt
    18541 gagcaatttt ataaggaaat tgactttatg caccgtaagt ggccggatgt tcagaagtat
    18601 ctggtttatt ttcaaaattt taccaacacc catgaaaagg tggaagttat tcgagagcgt
    18661 tatgaacagg ctatcaatga gccaggtgtg gtaggaatca atattggaac gcgcccagac
    18721 tgtttaccag acgaaaccat cgaatatttg gctgagttat cggagtgcat gcatgtgacg
    18781 gttgaattgg gcttgcaaac tacttatgaa gcaacctctg acctgattaa ccgtgcgcat
    18841 tcttatgaat tgtaggtgga aacggtcaag cgtttgagaa agtatccaaa aattgagatt
    18901 gtttcccatt tgataaatgg tttgcctggt gaaacccatg agatgatggt tgaaaatgtc
    18961 cgccgttgtg tcacggataa cgatattcaa gggattaaac tgcatttgct ccatcttatg
    19021 acaaatactc gtatgcaacg agattaccat gagggacgtt tacaattgat gagtcaggac
    19081 gaatatgtca gggtcatctg tgaccaactg gaaattattc ccaaacatat cgtcatccat
    19141 cgaattacag gagatgcgcc tagggatatg ctgattggtc ctatgtggag cctcaaaaaa
    19201 tgggaagtcc tcaacagcat tgagatggag atgcgacgtc gtggaagtgt tcaaggatgc
    19261 aaggttgtaa aacaggagtt tgaaaatgaa aagaccactt gagatggcac atgatttttt
    19321 ggctgaggtc gtgacaaaag aggatgtcgt agtggatgcg actatgggaa atggtcatga
    19381 cacgcttttt ttagccaagc tagccaagca agtctatgcc tttgatattc agaagcaagc
    19441 cttggaaaag acccaagagc gtttgcatca ggctgacttg acaaatgccc agttaatctt
    19501 gcaaggccat gagacactgg atcagtttgt gataaaagct aaggcaggga tttttaattt
    19561 gggctatttg ccgtcagctg ataagtctgt catcacccga ccgcagacaa cgattgaggc
    19621 attagaaaag ctatgtggct tacttgtcaa aggtggacga attgctatta tgatttacta
    19681 tggtcatgaa ggaggcgacc tcgagagaga tgctgtcttg gattttgtaa tccagttgaa
    19741 ccaacaagag tacacagctg ccatttaccg aactttaaac caagtcaaca acccgccgtt
    19801 tttagtgatg attgaaaaat tagagagata cagacatgga taaacaatac ctacacgaaa
    19861 agctggatgc catgcgccag aattttgttg aatcaaccca ccacgaacga tcggtgggcg
    19921 tgctagacca agcgcatatg agcaaaaaaa tgcttaaaat caagaaaaaa ttagttgctc
    19981 ttgaaatgga acggtgccag agaaaaattg agcacaaaga ctgttccaag attgaccaaa
    20041 aaatcaaaga gcagaaggag atatttgaat cctgttgtaa aaaagattaa ggaggacgtg
    20101 cgtggaatta ctgatttacc tcatcctatt tttactggtt ttgattgtct caagtacaac
    20161 caataagctc ctgccctttt tgcctctccc tttggtgcaa attcttttgg gaattgtgat
    20221 tggtctcttt ttacccaata ctgactttca ccttaatacg gagttgtttt tggcactggt
    20281 tatcggaccc ttgcttttcc gagaggctga agaagcagat gttacggcta ttttaaaaca
    20341 ctggcgaatc attgtttatc tcatatttcc agtgattttt atctcgaccc tgagtttggg
    20401 tggcttggcc catcttcttt ggttcagcct tcccttggca gcttgcttgg ctgttggtgc
    20461 agcccttggt cctacggact tggtggcctt tgtctctctt tcggagcgtt ttagctttcc
    20521 taagcgcgtg tccaatattc ttaagggcga aggactcttg aatgatgctt ctggtttggt
    20581 ggcttttcag gtagctttga cagcttggac aactggagct ttttctctgg ggcaagctag
    20641 cagttcgctc atcttttcaa tcctaggcgg ttttttaatt ggatttttaa cagccatgac
    20701 caaccgcttc ctccatacct tcttgctaag tgtgcgcgca acggatattg ccagtgaact
    20761 tttattagaa ttgagtttgc ctctagtgac cttctttctg gcagaagaag tccatgtttc
    20821 agggattatt gccgtcgtag ttgctggaat tttaaaggca agtcgcttca agaaaatcac
    20881 gctcctcgaa gcccaagtgg atacggtgac cgagacggtc tggcatacag tgacctttat
    20941 gctcaacggt tctgtctttg tgattttagg gatggagttg gaaatgatag cagaacctat
    21001 cttgaccaat ccaatctata atcctctact tttattgcta tctctcatcg cccttacctt
    21061 tgtcctcttt gtcattcgtt ttattatgat ctatggctat tatgcctata gaacccgacg
    21121 cctcaagaaa aagctaaata aatatatgaa ggacatgttt ctcttgacct tttcaggtgt
    21181 taagggaacg gtgtcgattg ctacgattct cttgatacca agtaatctag aacaggagta
    21241 tcctctcttg cttttccttg ttgcaggtgt gacgcttgtc agctttttaa caggtctctt
    21301 ggtcttgcct catctttctg atgaagagga agaaagcaag gattatctca tgcatatcgc
    21361 cattttgaat gaagtaacgc tagagttgga aaaagagttg gaagacacca gaaataaact
    21421 tcccctctat gcggctattg acaattatca tggacgtatt gaaaatctca ttttaagcca
    21481 agaaaaccag gatgatcaag aagattgggc tgctttgaaa ctcttgattc ttagtattga
    21541 aagtgatggt ttggagcagg cctatgaaga ggggaacatt agcaatcgtg cttaccgagt
    21601 ttaccaacgt tatctgaaaa atatagaaca aggaatcaat cgtaaacttg cctcaagact
    21661 gacctattat tttcttgttt ccttgaggat tttacgtttt ctccttcatg aagtttttac
    21721 tcttggaaag accttccgta gctggaagga caaggagcaa agccgtctcc gtgctcttga
    21781 ttatgaccaa attgcagagc tctatcttgc caatacagag atgattattg aaagtttgga
    21841 aaacctgaag ggagtctaca gacgctcttt gattagtttt atgcaggagt ctcgtcttcg
    21901 agaaacagct attatcagca gtggtgcctt tgtcgaacgg gttatcaatc gtgtcaaacc
    21961 caacaatatc gatgaaatgc tgagaggcta ttatctggag cgcaagttga ttttcgaata
    22021 cgaagaaaaa cgattaatta caactaagta tgccaagaaa ttacgacaaa atgtaaataa
    22081 cttagagaac tattccttga aggaagctgc caataccctg ccgtatgata tggtggaatt
    22141 ggtaagaaga aattagttaa tactcttcga aaatctcttc aaaccacgtc agcgtcgcct
    22201 tggattatat atgtgactga cttcgtcagt ttcatctaca acctcaaagc agggctttga
    22261 gcaacctgcg gctagcttcc tagtttgcta tttgattttc attgagtata agattataag
    22321 tgaaggagtg tgacatgaaa aagtggtgga aagagctgat agacaagcct ttattaaaag
    22381 cttttttgca ttattatcaa gcatcagata gtgagttgac cagtgtcgca gtagcctact
    22441 attggttgat ttcgatcttc cccctgcttt tggtggtggt caatatcctc ccctattttc
    22501 agattcctgt gggagaattt ctgggcttta tgaaagacgt tctgccccca agcctctatg
    22561 aaggtgtgga aaaaatagcc agagaagttt tgacgcaacc ttcaacaggt ttattgagtt
    22621 tttctgtttt atcggcgtta tggagttttt caaaatctat gaatttcttg caaaaagctt
    22681 ttaacaaggc ttatggcgtc gaaaagagtc gtggacttat ttcccatcag atgctaagtc
    22741 tcctagtcag ttttggcttg cagctcctct ttgcgtttgc cttgtttttg atcttatttg
    22801 gtcagatgat tttggcttta cttgctcatt attggacaaa agatggcatt atctatcagg
    22861 ctttacaagg gttggcaggt cctctgattt acgccctcct ctttgctatc ttggtcatgc
    22921 tttattattt tcttcccaat ctatctaaca ggaaaattag ctatacccta ccaggcagtg
    22981 cctttgttct cttagtgatt ttaggtttac taactctgtt ctctagttat ctcaattact
    23041 atgtccatca tttggtggat gtccgaattt taggttccgt tcttcttgtt gttatgatgt
    23101 tttggtttat cttgattgct aaaattgtta tcctaggcgc ggttatcaat gccagtatgc
    23161 agagtttgaa agatccggtc tttaaaaagg actaactatt tatctattat aaaagcgcat
    23221 agtatcaaga ctttatagaa ccttgatact atgcgctttt gtgctttgac agttttttgt
    23281 atagtttttg tccaagattt ctaaatcatc tgattaaatt cctattttcc cctatcattg
    23341 tccctgtttt ttcgaaaatg gaaggagtat aataaatcta tcaataaaat gataggagga
    23401 actttatggg tcatattttc ttttttctaa gtgtcttttt ggcagggatt ctatccttct
    23461 tttctccttg tatcttacct ttgttaccgg tctatacagg ggtgttacta gatgataagg
    23521 atggtgctca gacttctagc ggcaaatttt caatctcagt tactagttta ttacgaactc
    23581 tggcctttat agcaggaatt tcctttatat ttattttgtt gggctatgga gctggttttt
    23641 taggcgattt gctttatgct tcttggttcc aatatcttac tggggcaatt attatccttc
    23701 ttggtttgca ccaaatggag attctacact ttaaggggct ttataaggaa aagaggctac
    23761 aactgcaagg acaggggcaa aatggtaagg gctatagtca ggcattttta ttgggcttga
    23821 cctttagttt tgcttggacg ccttgcgtgg ggccggttct ggggtctgtt ttggccttgg
    23881 cggcttcagg tggttcagga gcttggcagg gagctggtct catgttggtg tatacgctgg
    23941 gcttggcgct accattcttg cttctagctc tgacctctag ttatgttttg aaacatttcc
    24001 gaaaacttca tccctatctc ggaatcctca aaaaagtggg tggttttctc attattgtga
    24061 tgggactctt ggttctgttt ggaaatgctt caattttaag tcaattattt gaataaaatg
    24121 gaaaggaata tcaatatgaa aaaatggcaa acatgtgttc ttggagcagg ttcgctcctt
    24181 tgtttgacgg cttgttcagg caagtccgtg actagtgaac accaaacgaa agatgaaatg
    24241 aagacggagc agacagctag taaaacaagc gcagctaaag ggaaagaggt ggctgatttt
    24301 gaattgatgg gagtagatgg caagacctac cgtttatctg attacaaggg caagaaagtc
    24361 tatctcaaat tctgggcttc ttggtgttcc atctgtctgg ctagtcttcc agatacggat
    24421 gagattgcta aagaagctgg tgatgactat gtggtcttga cagtagtgtc accaggacat
    24481 aagggagagc aatctgaagc ggactttaag aattggtata agggattgga ttataaaaat
    24541 ctcccagtcc tagttgaccc atcaggcaaa cttttggaaa cttatggtgt ccgttcttac
    24601 ccaacccaag cctttataga caaagaaggc aagctggtca aaacacatcc aggattcatg
    24661 gaaaaagatg caattttgca aactttgaag gaattagcct aggaggtgtc tcatgaatga
    24721 taagttaaaa atcttcttgt tgctaggagt attttttcta gccataaccg gtttctatgt
    24781 tctattgata cgaaatgcag ggcagacaga tgcctcgcaa attgaaaagg cggcagttag
    24841 ccaaggagga aaagcagtga aaaaaacaga aattagtaaa gacgcagact tgcacgaaat
    24901 ttatctagct ggaggttgtt tctggggagt ggaggaatat ttctcacgcg ttcccggggt
    24961 gacggatgcc gtttcaggct atgcaaatgg tagaggagaa acaaccaagt acgaattgat
    25021 taaccaaaca ggtcatgcag aaaccgtcca tgtcacctat gatgccaagc aaatttctct
    25081 caaggaaatc ctgcttcact atttccgcat tatcaatcca accagcaaaa ataaacaagg
    25141 aaatgatgtg gggacccagt accgtactgg tgtttattac acagatgaca aggatttgga
    25201 agtgattaac caagtctttg atgaggtggc taagaaatac gatcaacctc tagcagttga
    25261 aaaggaaaac ttgaagaatt ttgtggtggc tgaggattac catcaagact atctcaagaa
    25321 aaatccaaat ggctactgcc atatcaatgt taatcaggcg gcctatcctg tcattgatgc
    25381 cagcaaatat ccaaaaccaa gtgatgagga attgaaaaag accctgtcac ctgaggagta
    25441 tgcagttacc caggaaaatc aaacagaacg agctttctca aaccgttact gggataaatt
    25501 tgaatccggt atctatgtgg atatagcaac tggagaacct ctcttttcat caaaggacaa
    25561 gtttgagtct ggttgtggct ggcctagttt tacccaaccc atcagtccag atgttgtcac
    25621 ctacaaggaa gataagtcct acaatatgac gcgtatggaa gtgcggagcc gagtaggaga
    25681 ttctcacctt ggccatgtct ttacggatgg tccacaggac aagggcggct tacgttactg
    25741 tatcaatagc ctctctatcc gctttattcc caaagaccaa atggaagaaa aaggctacgc
    25801 ttatttacta gattatgttg attaatactt ttcgaaaatc tcttcaaacc acgtcagcgt
    25861 cgccttaccg tatgtagggt tactgacttc gtcagtttta tctacaacct caaagctata
    25921 ctttgagctg acttcgtcag ttttatctac aacctcaaag cggtactttg agaaacctgt
    25981 ggctatcttc ctagtttact ttttgatttt tattgagtat aagaggtctt tcctaagcag
    26041 ttagaggaga attttgctat actgatacta gtaagtggta aaggagcaga tcatgaccta
    26101 cacaatctta atcgtagaag atgaatatct ggtaagacaa ggtttgacta aactggtcaa
    26161 tgtagcagcc tacgatatgg aaatcatcgg tcaggctgaa aatggaaggc aggcttggga
    26221 attgatccaa aagcaggtgc cagatatcat tttaaccgat atcaacatgc ctcatctaaa
    26281 tggcatccag ttggccagtc tggtacgaga aacctatcct caggttcatt tggtcttttt
    26341 aacaggttac gatgattttg attatgcctt gtctgctgtc aaactaggtg tggacgacta
    26401 cctgctcaaa cccttttctc gtcaggatat tgaggaaatg ttggggaaaa tcaaacaaaa
    26461 actagacaag gaagagaaag aagagcagtt acaagattta ttgactaata ggtttgaagg
    26521 aaacatggcc cagaaaatcc agtctcatct ggctgatagc caatttagtt taaagtcttt
    26581 agccagtgac ttaggtttta gtccgaccta tctgagttcc ttgattaaga aagagttggg
    26641 cttgcctttt caggattatc tggtgagaga acgtgttaaa caagccaagc tcttgctttt
    26701 aactacagat ctgaagattt atgagatcgc agagaaggtt ggttttgaag atatgaacta
    26761 ttttacccaa cgttttaagc agattgcagg tgtgacacct cgtcagttta agaagggaga
    26821 agaccgatga agcgttcttc tcttttagtt agaatggtta tttccatctt tctggtcttt
    26881 ctcattctcc tagctctggt tggaactttc tactatcaat caagttcttc agccattgag
    26941 gccaccattg agggcaacag ccaaacgacc atcagccaga ctagccactt tattcagtct
    27001 tatatcaaaa aactagaaac cacctcgact ggtttgaccc agcagacgga tgttctggcc
    27061 tatgctgaga atcccagtca agacaaggtc gagggaatcc gagatttgtt tttgaccatc
    27121 ttgaagtcag ataaggactt gaaaactgtt gtgctggtga ccaaatctgg tcaggtcatt
    27181 tctacagatg acagtgtgca gatgaaaact tcctctgata tgatagctga ggattggtac
    27241 caaaaggcta ttcatcaggg agctatgcct gttttgactc cagctcgtaa atcagatagt
    27301 cagtgggtca tttctgtcac tcaagaactt gttgatgcaa agggagccaa tcttggtgtg
    27361 cttcgtttgg atatttctta tgaaactctg gaagcctatc tcaatcaact ccagttgggg
    27421 cagcagggct ttgccttcat tatcaatgaa aaccatgaat ttgtctacca tcctcaacac
    27481 acagtttata gttcgtctag caaaatggag gctatgaaac cctacatcga gacaggtcag
    27541 ggttatactc ctggtcacaa atcctacgtc agtcaagaga agattgcagg aactgattgg
    27601 acggtacttg gcgtgtcatc attggaaaag ttagaccagg ttcggagtca gctcttgtgg
    27661 accttgcttg gggccagtgt cacatctctt cttgtctgtc tctgcttagt gtggttcagt
    27721 cttaaacgct ggattgctcc tttgaaggat ttgagagaaa ccatgttgga aattgcttct
    27781 ggtgctcaaa atcttcgtgc caaggaagtt ggtgcctatg aactgagaga agtaactcgc
    27841 caatttaatg ccatgttgga tcagattgat cagttgatgg tagctattcg tagccaggaa
    27901 gaaacgaccc gtcagtacca acttcaagcc ctttcgagcc agattaatcc acatttcctc
    27961 tataacactt tggacaccat catctggatg gctgaatttc atgatagtca gcgagtggtg
    28021 caggtgacca agtccttggc aacctatttc cgcttggcgc tcaatcaagg taaggacttg
    28081 atttgtctct ctgacgaaat caatcatgtc cgccagtatc tctttatcca gaaacaacgc
    28141 tatggagata aactggaata cgaaattaat gaaaatgttg cctttgataa tttagtctta
    28201 cccaagctgg tcctacaacc ccttgtagaa aatgctcttt accatggcat taaggaaaag
    28261 gaaggtcagg gccatattaa actttctgtc cagaaacagg attcgggatt ggtcatccgt
    28321 attgaggatg atggcgttgg cttccaagat gctggtgata gtagtcaaag tcaactcaaa
    28381 cgtgggggag ttggtcttca aaatgtcgat caacggctca aacttcattt tggagccaat
    28441 taccagatga agattgattc tagaccccaa aaaggaacga aagttgaaat atatataaat
    28501 agaatagaaa ctagctaact cccagtcaat tctgggagtt ttatgcgtaa ttgggcaaac
    28561 tttctaggtt gtctatcttg ctaaaaacaa gaaaaaacgg tatgatagaa gagtgacaac
    28621 agaggtaaca gagatgaacg agacacagat tcaaagagaa acacgtcagg tagtggaaga
    28681 tgttttagaa aagaccaatt tgaaacaggg ggcccttttt gttttaggtc tatcttctag
    28741 tgaggtgcta ggtggtcaga ttgggaaaga atccagtcaa gagattggtg agctgatagt
    28801 ggagactatc ttgggtattc taggtagtag aggtatccat ttagcagttc aaggttgtga
    28861 gcatgtcaat cgggctctcg ttgttgaacg tcaggtggca gagcagtttg gtctggaaat
    28921 tgtcagtgtc catcctactc ttcatgcagg aggttcgggg cagttggcag cctttaagtt
    28981 tatgcaggat ccagttgagg ttgaatttat caaggctcat gctggattgg atatcggaga
    29041 cactgcaatt ggcatgcatg tcaagcatgt tcaggttccg attcgcccta ttttgagaga
    29101 gattggtcat gcccatgtaa cggcactgac tagtcgtcca aaattaatcg gaggtgcgcg
    29161 tgcgcactat ccgcaagacg ctattagaaa gtcttgagaa tgaataaagg agataaaagt
    29221 gtttaaaaaa gaccgttttt caattcgtaa gattaaggga gttgtaggct ctgtatttct
    29281 tggaagcctt ttgatggctc cttctgtagt ggacgcagcc acctatcact atgtaaataa
    29341 agagattatt tcacaagaag ctaaagattt aattcagaca ggaaagcctg acaggaatga
    29401 agttgtatat ggtttggtgt atcaaaaaga tcagttgcct caaacaggga cagaagcatc
    29461 tgttttgaca gcttttggtt tgctgactgt tgggagcttg cttttaatct acaagagaaa
    29521 gaaaattgct agcgtctttc tagttggagc tatgggattg gtagttcttc ctagtgcaga
    29581 ggctgtagac ccagttgcga ccctagcgct ggctagtcga gagggtgttg ttgaaatgga
    29641 tggctatcgc tatgttggtt atctatcagg tgacatcctc aaaacgcttg gcttggacac
    29701 tgttttagaa gaaacctcag cacaacctgg agaggtgact gtagtcgaag ttgagactcc
    29761 tcaatcaaca acaaatcagg agcaagctag gacagaaaac caagtagtag agacagagga
    29821 agctccaaaa gaagaagcac ctaaaacaga agaaagtcca aaggaagaac caaaatcgga
    29881 gataaaacct actgacgaca cccttcctaa agtagaagag gggaaagaag attcagcaga
    29941 accagctcca gttgaagaag taggtggaga agttgagtca aaaccagagg aaaaagtagc
    30001 agttaagcca gaaagtcaac catcagacaa atcagctgag gaatcaaaag ttgaaccacc
    30061 agtagaacaa gcaaaagtcc cagaacaacc cgtgcaacct acacaagctg agcaaccaag
    30121 tacaccaaaa gaatcatcac aagaagacaa ttctaaagaa gataggggag cggaagagac
    30181 accgaaacaa gaagatgaac agccagcaga agccccagaa atcaaggttg aagaaccagt
    30241 agaatcaaaa gaggagactg ttaatcaacc tgttgaacaa ccaaaagtgg aaacgcctgc
    30301 tgtagaaaaa caaacggaac caacagagga accaaaagtt gaagtaacaa cagttgaaac
    30361 aagagaagaa gtcattcctt ttgaaacaaa agaacaagaa gatgacactt taaaacgcgg
    30421 aacaagacaa gtagttcaaa aaggtgtaga aggtaagaaa caaattactg aaacttataa
    30481 aacaattcgt ggagaaaaaa caaatgaagc tccaatagtt aaggaaacag taattgaaca
    30541 acctcaagat gagattatca aaaaaggtac aaaagggtta gaaaaaccaa cattacaatg
    30601 ggctaatact gaaaaagatg tcttgaagaa gagtgctaca gctagttata cattgactaa
    30661 accagctggt gtagaaatta aatcaattaa attagcgcta aaagataaag atggacaact
    30721 tgttaaagaa gtaacggtag ctgaaaataa tttaaatgct actttagata aattgaaata
    30781 ttatcaaggt tacaccctat ctactacaat ggtttatgat cgtggagaag gtgaagaaac
    30841 tgagaaatta gaagataaac aaattcaatt agaccttaaa aaagttgaaa tcaaaaacat
    30901 taaagaaaca agcttaatga atgttgatgc tgagggtaac gaaactgata agagcttatt
    30961 atctgaaaaa ccgacagatg tttcccaatt gtatttacgt gtgacaactc atgacaacaa
    31021 agtgacaaga cttgcggtaa gttcagttga agaagttgtt gttgatggaa aaacattgta
    31081 caaagttgta gccaaagctc cagacttagt tcaacgtaga gctgatgata cactgagtga
    31141 agaatatgtt cattattttg aaaaacaatt accaaaagta aataatgtat actacaactt
    31201 caatgaactt gtaaaagata tgcaagctaa tccaacgggt gagtttaaac ttggtgcaga
    31261 cttgaatgca gcaaatgtaa aacctaacgg gaaatcttat gtaacgaaac catttaaagg
    31321 gaaattacta agtaatgacg gcggtagatt tacaatccat aatatagaac gtccattatt
    31381 cgctaatatt gaaggtggta aaatccacga tattaatctt gctaatgtaa atattaatat
    31441 gccttgggct gataaagttg ctcctattgc aaatgtaatc aaaaataatg caaccattga
    31501 aaatgtcaaa gttactggta atgtcctggg taaagactgg gtatctggat ttatagacaa
    31561 aattgacggc agtggtaaat taattaatgt tgcatttatc ggtaatgtta catctgttgg
    31621 tactggaggc aacttcttaa caggtattgt gggagaaaac tggaaaggat acgttgaaag
    31681 agcatatgtt gatgctcata ttaaaggtaa gcgagctaaa gctgcgggta tagcctactg
    31741 gtcacaaaac caagggaata actttactat tggatctgag ggggctatta aaaaatctgt
    31801 tgttaaaggt acaatagacg ttgaaaaacc aattgaagtt ggtggcgctg ttggaagttt
    31861 tacttatcat ggttctattg aagatactgt ttctatgatg aaagttaaga acggtgaaat
    31921 tttctatggt tctaaagata ttgatgatga tccatattac acaggtaacc atgttaatcg
    31981 aaactacgtt gttataggtg ttagcgaagg tacttctaca tatagatatt ctaatcagca
    32041 taatcgtatt aaacctataa cacaatcaga agctgatgtt aaaattgcag agacagctat
    32101 cacagcagat aaatttacaa ttaccgatcc aattgtaaat aaacttaacg ctctcacaac
    32161 acgtgataat gagtatagaa caacacaaga ttacaaggcg actcgcgaac aagcttatcg
    32221 caatattgaa aaacttcaac cgttctataa caaagaatgg attgtcaacc aaggtaacaa
    32281 acttgtagaa ggttcaaact tgttgacaaa agaagtatta tctgttacag gtataaagag
    32341 cggtcaattc gtaactgatt tgtcagatat tgataaaatt atgattcact attctgatgg
    32401 agcaaaggaa gaattgaatg ttactcgtca agaatcaaac gttcaacaag tgcgtgagta
    32461 cagtattaca gatttagata tactctatac accaaatatg gttgagaaag atcgcgctca
    32521 gttgatgact gatgtaaagt ctaagctatc tagtgtagaa ttagagtctg atggagtgcg
    32581 tcaacttctc gttaagagag atactaagaa agatgcgaat gcaaatagtg taggtcgtca
    32641 aaatggatac attagagatt tattccttga agaaagtttc tctgaagtta aagcaaatct
    32701 tgacaaattg gtaaaacaga tacttgaaaa tgaagatcat caactcaacg ataacgaatt
    32761 agctgaacgt gctttactga agaaagttga agataataaa gctaaaatca tgatgggact
    32821 ggcatactta aatcaatatt atgcttttaa atacgatgag ttatcaatta aagatattat
    32881 gatgtttaaa cctgattttt atggtaagac agcaagtgtt attgatagat tgattaatat
    32941 tggttctgca gaaaataatc taaaaggaga tagaacgcaa gatgcttatc gtggtataat
    33001 ttcaggggca acaggtaaag gtagtttaca tgacttcttg acctacaata tgaaattatt
    33061 cacaaatgaa acagacataa atgtttggtt taagaaagct attgaaaaga atgcttatgt
    33121 agttgaacaa ccatcaacga accctgcatt tgccaacaaa aaatatcgtc tatacgaagg
    33181 aattaataat gggcaacatg ggcgcatgat tttacctctt cttaacttga aaaatgcaca
    33241 tctatttatg atttcaacat acaacactat ctcgtttagt tcgtttgaaa aatatggcaa
    33301 agacacagat gaaaaacgtg aaaagttcaa gagtgagatc aataaacgtg ctaaagagca
    33361 ggttaattac ttagattttt ggtcacgtct tgctactgat aatgtccgtg ataaacttct
    33421 taagagtcaa aatgtagttc caactcctgt atgggataat cataatagcc cgaacggatg
    33481 ggctagtaga catggtcata tagatgggaa accagattat gctccaattc gtgagttctt
    33541 tgggcgaatc aataagtatc atggttacaa atatggatat ggcgcatatg catatatttt
    33601 tgcagcacct caaccgatgg atgcagttta tttcgttatg acagatttaa ttagtgactt
    33661 tggaacatct gcatttacac atgaaactac tcacgttaat gatcgtatgg cttactatgg
    33721 tggtcattgg catcgtgaag gtacggatct tgaagcattt gctcagggga tgttacaaac
    33781 gccatcggta tcaaatccaa acggagaata tggcgcatta ggtctaaata tggcgtatga
    33841 acgtcaaaat gatggaaatc aatggtataa cacaaatcca aacgacctta caactcgtgc
    33901 agaaattgat aactacatga aaggtttcaa cgacacatta atgcttcttg attaccttga
    33961 aggagaagct gtcctcaata aagcaaatca agatttaaac aacgcttggt tcaaaaaagt
    34021 ggataagcaa cttcgtggag ctagtacgaa gaaccagtat gataaagttc gtgatttaac
    34081 ggcagatgag aaaaatatca ctctaaattc agtagatgat ttagttgata ataattttat
    34141 gacgaaacac ggacctggaa acaatgtata tgatccaact gggttcggaa cggcctacgt
    34201 gactgtacct attactgcag gtatttatgg aggtaacaca agtgaaggtg ctcctggttc
    34261 tatgtcattc aaacataaca cattcagaat gtgggggtac tacggatatg aaaaaggatt
    34321 cttaaactat gcttctaaca tgctgaaaaa tgagtctaga caggctggtc acaatactct
    34381 aggtgatgat ttcatcatta agaaagtttc tgataataaa ttcagtacat tggaagattg
    34441 gaagaaagca tacttcaaag aagttgtaga taaagctaaa gaaggattta accctgttac
    34501 aatcgacagt actacatata gtagttacga tgacttgaag aacgcatttg ctgcagcagt
    34561 tgaaaaagat aaagctactc ttaaaaatgg atcagttaaa tctgacaata ctgttgcact
    34621 taaagagaaa atatacaaaa aacttcttca acaaacagat agctttaaaa cttcaatctt
    34681 tagataatcg aaatctctca tctgctttgc ggatgagggt tttcttattt tatgctatac
    34741 ttaaggtatg catagaaaaa cagtgattga ttttaggact ttaggggaga gatatacctt
    34801 tacccagcct attaaagagt tgaaaacgag aaatgtagaa gaagtggcag atttgctggc
    34861 acaagtggaa agctaccaag agcaaggtta ttatgtggtg gggtatgtca gctacgaggc
    34921 tgcacctgct tttgaggaga aattaacagt tcacaaggtt cctctactgg gcgagtactt
    34981 gctttacttt actgttcacg atagggtaga gacctcccct gttcctctga cttatgagga
    35041 tattgatttg ccctcaaatt ggcaggaagt gacgtctgca gcagactatg aaaaggccat
    35101 tgcccagata caccatcact tgaggcaggg agacacctat caggtcaact acaccgtcca
    35161 actcaagcaa aagttaagtg ccaatccttt tgccatctac aatcgtatgg tggtagagca
    35221 ggaggcgggc tacaatgcct acgtggaaca tgacgagatg gcagtgattt ccatgagccc
    35281 agagctcttt tttgagcaaa atgatcgcga gttgacaaca cgaccaatga aggggacgac
    35341 tcagcgtggg gtaactgacc aagaagatct tgaacaggcc agttggttgg aacaggatcc
    35401 caaaaatcgc tctgaaaata tgatgattgt ggacctcttg cgcaatgata tgaaccgtat
    35461 ttctgaagtt gggagcgagc acgtggagcg tctgtgtcag gtagagcagt attcaactgt
    35521 ttggcagatg acttcgacca tcaagagtca gttgcgagag gatgtggacc ttgttgaaat
    35581 cttccgctca ctctttcctt gtggttccat aacgggtgca ccgaaaattg cgacaatgga
    35641 gattatcaag gacttggagc ctcaaccgcg tggagtctac tgtggaacga ttggtctctt
    35701 gcttccaaat ggacgacgga tttttaatgt ggccattcgt accattcaac ttcacaaagg
    35761 tcaagccatt tatggagttg gcggagggat tacttgggat agcacatggg aatctgaata
    35821 ccgagaggtt catcaaaagg cagcagttct ttatcgtaaa caagctcgct tccaactgat
    35881 tacgacaggg gaaatcagcc agaagaacct gctgtttgaa gatcaacatc tggaaagact
    35941 gagaaaagct agtcgttatt ttgcttttcc ttttgatgca gaagacttgg gacacaagat
    36001 tgaggaagag tgtcaggatt gtgaagctaa tcgagattac cgcttgcgaa tcagccttag
    36061 caaatctgga gagatagaag tcaatcgtca agtattaacc cctctcagta caagcttttg
    36121 tcaggcccaa gtctgtcttc aggaagctgc tttgaatcaa tcctttacct actttaaaac
    36181 cactcaccga tcgcatttga gcctaggaga acaagagaag atttaccaca ataagtcagg
    36241 agaactgctt gaaacctcta taggaaattt ggttctgaaa atcgctggaa aactctacac
    36301 accgcctatc cgacttggaa tcttgccagg aatttaccgt cagcatttgc tagaaacagg
    36361 acaggtagaa gagaaagtct tgaccttggc agatttaacc caagcagaag ctatttacgg
    36421 ctgtaatgca gtgagaggct tgtatgaact aagccttgag gagaactaga tgaaattgat
    36481 atttttgcat gggttagggc agtcagcaga gtcttggaaa gaagttcgga atctactgac
    36541 agattatcct tctgaggcta tcgagttatt tccttctgga gttagtaact atcaacaagc
    36601 taaagagcga gtttatcagc acctagctca agagacagaa ccttttgttt tgattggatt
    36661 gtccttaggt gctgccctga cactagaact ttccagttac gatttaccaa atcttcgagc
    36721 tttgattctg tcaggatgcc cgcttaaatt agcagggaat atcctatttt atcttcagtt
    36781 gctgattttt aaactacttc ccaaaagagt atttgaaaaa cagggagcag acaagactct
    36841 tatggtcgga gtttctgagg aattgaagac acttgattta acggatatag cagggacttg
    36901 ctcctatcca accttactaa tttgtggcag caaagataaa ccgaatctta gttctatgaa
    36961 agctctccat agactgttaa cagattcgca gtttcagatc attcctgatg gccctcatgt
    37021 cttgaataag gcaaaaccaa aggagtttgt agaaaagacc agaagtttct ttgaattgct
    37081 gaaataagtt tgataaaata atattgaaat cgatatcata attatgggag aaagaaatga
    37141 ataaacgtct atttttaaaa atgagtctgg tgacgttgcc aattttagcc ttgttttcac
    37201 aaccagtttt ggcggaagaa aacatccatt tttcgagctg taaggaagct tgggcgaatg
    37261 gctattcgga tattcacgag ggagaacctg gttattctgc caagttagac cgtgatcatg
    37321 atggtgtggc ttgcgaattg aaaaatgctc ctaagggtgc ttttaaagca aaacagtcaa
    37381 cggctattca aatcaacaca agttcagcaa caacaagtgg ttgggttaag caggacggcg
    37441 cttggtacta ctttgatgga aatggaaatc tagtgaaaaa tgcatggcag ggaagctatt
    37501 acctgaaatc agatggtaaa atggctaaag gtgaatgggt ttatgatgtc acctatcaag
    37561 cttggtatta tttgacatca gatggttctt atgcttacag tacatggcaa ggaaattact
    37621 atctaaaatc ggatggtaaa atggctgtca atgaataggt tgatggtgga cgttattatg
    37681 ttggcgctga cggagtttgg aaggaaggtc aagcaagtac agtttcttct agtaatgata
    37741 gcaatagtga atattctgct gctttaggaa aggcaaaaag ttataattcg ttattccaca
    37801 tgtcaaaaaa acgtatgtat agacaattaa cttctgattt tgataaattt tcaaatgatg
    37861 cagctcaata tgccattgat catttagatg attaacagat actggtaggc gaaaaaattc
    37921 cttataattc atttacgcaa acctttgcat aagtgaatgg attttgatat actagtactg
    37981 taagcatttt caattactac acaatgaaaa aggagaatat gatgagtcaa aagattattg
    38041 ggattgacct tggtggaact tctatcaaat ttgcaatctt aacaacagca ggagaaatcc
    38101 aaggaaaatg gtcaatcaag accaacattt tggatgaggg aagtcatatc gttgatgata
    38161 tgattgagtc tattcaacat cgtttggact tgcttggatt ggcagcagcg gacttccaag
    38221 gcattggaat gggatcacca ggtgtggttg accgtgacaa agggactgtt atcggtgcct
    38281 acaacttgaa ctggaaaacc cttcaaccaa tcaaacaaaa gattgaaaaa gctttgggca
    38341 ttccattttt catcgataat gatgccaacg tagcagctct tggtgagcgc tggatgggtg
    38401 ctggagataa ccaaccagac gttgtcttta tgacactcgg tactggtgtt ggtggtggta
    38461 ttgtcgcaga aggcaaattg cttcatggtg ttgctggtgc agcaggtgaa cttggtcata
    38521 tcactgttga ctttgaccaa ccaatctcat gtacttgtgg taaaaaaggc tgccttgaga
    38581 cagttgcttc agcaacaggg attgtcaact tgactcgtcg ctatgccgat gaatacgaag
    38641 gcgatgcagc cttgaaacgc ttgattgata acggagaaga agtaactgct aagactgtct
    38701 ttgatctcgc aaaagaagga gacgaccttg ctttgattgt ttaccgtaac ttctcacgtt
    38761 acttgggaat cgcttgtgct aacattggtt caatcctaaa cccatcaaca atcgtcatcg
    38821 gtggtggtgt gtcagccgcg ggagaattcc ttctacaagg tgttcaaaaa gtttacgatg
    38881 aaaatagttt cccacaagta cgcacatcta ctaaattagc tcttgcaact ctaggaaatg
    38941 acgctggagt tatcggagca gcatcacttg tattgcaata agataatgag agaggaaaat
    39001 gctaacctag agttagtaat gttcctcttt tattttttat gctatactag ttaggacaat
    39061 gaatgaggtg aaacgaaatg acaaaagcag atacgatttt taaagagaat attgaacgca
    39121 ttctaaagga aggtgttttc tcagagcagg ctcgtcctaa gtacaaggat gggactgttg
    39181 ctaattccaa gtatgtaact ggtgcctttt ccgagtacga cttatctaaa ggagaatttc
    39241 ctatcacaac cttgcgtccc attgcaatca aatccgccat caaagaagtt ctctggattt
    39301 accaagacca gtcaaatagc ttagaagtgc ttaatgacaa gtacaatgtt cactactgga
    39361 atgactggga agttggagac acgggaacca ttggtgagcg ctatggtgcc gttgttaaga
    39421 aacacgacat tatcaataag cttctcaaac agttggaaac caatccttgg aaccgccgca
    39481 atattatttc gctctgggat taccaagctt tcgaagaaac agatgggctg ctcccgtgcg
    39541 cctttcagac catgtttgat gttcggcgtg ttgatgggga aatctatctg gatgcgacct
    39601 tgacccagcg ctccaatgat atgctggtgg cccaccacat caacgctatg cagtatgtgg
    39661 ctttgcagat gatgattgct aaacattttg gctggaaggt tgggaagttc ttctacttca
    39721 tcaacaacct ccatatctat gataatcaat ttgaacaagc tcaggaattg ctccgtcggg
    39781 agccgtcaaa ctgccaacca cgcttggttt taaatgttcc tgatgggact agtttctttg
    39841 atatcaaagc agaagatttt gagttggtgg attatgaccc tgttaagcca cagttgaagt
    39901 ttgacctagc tatttaaaag aatagaaaaa agaagttgag aataatccca acttcttttg
    39961 tttcttaacg tgatacgcgg cgacgagctg cttttttacg gttttcttcg atgaaagctg
    40021 ctttttgctc ttctggttcg attactttct ttttaaatgc gtatactgca cctgcaacgg
    40081 cagcgacagt tcctgcgaca cctgttacaa gacctttagc gaatccttta gccatgagtc
    40141 ttcctccttt atattctcaa tcagccagcc tcctcaagag gtcacatttt tctgactgac
    40201 ctttttgtgt tataataata gtaacgaaaa aatgggaatt tttcaaggaa aaaagatgaa
    40261 aacaaaaata attgtgattg ttggaccgac tgctgttgga aagacggctc tagctattga
    40321 agttgcaaag cgctttaatg gcgaagtggt tagtggagat agccagcaag tctatcgagg
    40381 acttgatatt gggacggcca aggctagtcc agaagagcag gcagctgttc ctcatcattt
    40441 aatcgatgtt agagagataa ccgagtctta ctcggctttt gattttgttt cagaagctaa
    40501 gatgactatt gaggatattc acagccgtgg caagctagcc attatcgccg gtgggactgg
    40561 actttatatc cagagcttgc tagaaggtta ccacctaggt ggggagactc ctcatgagga
    40621 gattttagct tatcgagcta gtttggagcc atattcagat gaggaattag cccatttggt
    40681 ggagcaagca ggccttgaga ttccccagtt taatcgtcgt cgtgctatgc gtgccttaga
    40741 aattgcccat tttggtcagg atttggaaaa tcaagagatt ttgtatgaac cgctgattat
    40801 ctgcttggat gatgaacgta gtcaacttta tgagcgtatc aaccaccgag tggatttgat
    40861 gtttgaggct gggcttttgg atgaggccaa gtggctgttt gaccattccc ctaatgtaca
    40921 ggctgctaaa ggaattggct ataaggaact ctttccttat ttccgtggag agcagacctt
    40981 ggaggaagct cgtgagagtc ttaaacaggc gacccgtcgt tttgccaagc gtcagctgac
    41041 ctggttccgt aatcgcatgc aggtcacctt ttatcagatt ggagaatctg gtgtacaaga
    41101 ccgcatttta agccagatag aggagttttt agatgattga aacggagaaa aaagaggagc
    41161 gagtcctgct gattggtgtg gaattgcagg gtatggacag ttttgacctc tccatggaag
    41221 aattggctag tttagcgaaa acggcagggg cagtcgttgt agataactac agacaaaaac
    41281 gtgaaaaata tgattccaag accttcgtcg gctctggtaa gttggaagag attgcgctta
    41341 tggtggatgc agaagaaatc actactgtca tcgtcaacaa ccgtctgaca ccaaggcaga
    41401 atgtcaatct agaggaagtt ctgggtgtca aggtcattga ccgtatgcag ttgattttgg
    41461 atatctttgc catgcgggct cgaagccatg aagggaagct ccaagtccac ctagcccaac
    41521 tcaaatacct cttgcctcgc ttggttggtc aggggattat gctcagccgt caggcagggg
    41581 gaattggttc ccgtggtcct ggtgaaagcc aactggagct gaaccgtcgt agcgttcgca
    41641 atcaaatcac ggatatcgag cgccagctca aggtggttga gaaaaatcgg gcgactgtca
    41701 gagaaaaacg tttggagtct agcaccttta agattggttt gattggttat accaatgctg
    41761 ggaaatcaac tatcatgaac atcttgacca gtaagaccca gtatgaagca gatgagctct
    41821 ttgcgactct ggatgcgaca accaagagta ttcatctggg aggcaatctc caagtaactt
    41881 tgacagatac cgttggcttt atccaagatt tgccgacaga gttggtgtcc agtttcaagt
    41941 caaccttgga agaaagcaag catgtggacc ttctggttca tgttatcgat gctagcaatc
    42001 cttatcacga ggagcatgaa aaaacggttc tctccatcat gaaagacctg gacatggaag
    42061 atattcctca cttgacgctt tataataaag cggatttggt ggaggatttc acgcctaccc
    42121 aaacgccata taccctcatt tctgccaagt ctgaggacag tcgtgaaaac ttgcaagcat
    42181 tattgctaga taagattaag gaaatttttg aagcatttac cctgcgagtg cctttttcaa
    42241 agtcctacaa gattcatgat ttagagagtg ttgcaattct ggaagaacgt gattatcagg
    42301 aagacagcga agtgattaca ggctacattt ccgaaaaaaa taaatggagg ttagaagaat
    42361 tttatgactg atattaaagc tttggctcta aagtatggag gttatacaag tctggacaag
    42421 gtctatctgg atcagcttct agctggtaaa acagagcagg agcagttaac acttattaca
    42481 cctccgccaa gtgttgttaa tgcctacttt gcagaactct atcagaaaaa gagtcctcag
    42541 gctgcgacgg attattttgc agaactcagt caggaactga atctttacaa tactgagcca
    42601 agtttcaccc tagaaaataa gccttttatt cggcttaatc tgtctggtaa atcctttggt
    42661 ttttgttatg agagtgacgg ccttggtcgg attttctctg aaaatgagga gaaaatctcg
    42721 gatgacttgc tctttgaaat tgcgcaaatt ttcccccatc aattagtctt tgaagagtct
    42781 ggtaagattt acatgaagcc tgtcgaggac gaggaagttg tcagcctaga aagtctcaca
    42841 gctttgactg atttggaaag attggctgat ggtcgaaaac gtctcaaagg ctacagccaa
    42901 gaggatttat tgcaagaagc tgctgctttt tctggcaaac gctatttccg atcggaaaac
    42961 cgcacagcca tgttatatat tgattaatta gaaagtatcg aatggatatt caatttttag
    43021 gaacgggggc tggtcagccc tctaaagctc gcaacgtttc aagtctcgcc ctgaaacttt
    43081 tggacgagat taacgaagtt tggctctttg actgtggaga aggtacgcaa aatcgcattc
    43141 tggaaaccac aattcgacca cgtaaggtca gcaaaatctt tattacccat ctgcatggag
    43201 accacatttt tggtttgcca ggtttccttt ctagccgtgc ctttcaggcc aatgaagagc
    43261 agacagattt ggaaatctac ggacctcaag gaatcaagtc atttgtctta accagccttc
    43321 gtgtgtcagg ttctcgtctg ccctaccgca ttcatttcca tgagtttgac caagattctc
    43381 taggtaaaat tcttgaaacc gataaattca ctgtgtatgc agaggagctg gaccacacta
    43441 ttttctgtgt tggctatcgt gtcatgcaaa aggatctaga agggacgctg gatgctgaaa
    43501 aactcaaggc tgctggtgtt ccgttcggcc cgctttttgg taaaatcaaa aatggccagg
    43561 atcttgtttt ggaagacgga actgaaatca aggcagcaga ctatatctca gcgccacgtc
    43621 caggtaagat tatcactatt ttaggagaca ctcgaaaaac ggatgccagt gtgcgtctgg
    43681 ctgtcaatgc agatgtccta gttcatgagt ccacttatgg caagggtgat gaaaaaattg
    43741 ctcgtaacca tggtcactca actaatatgc aagctgcaca agtagcggta gaagcaggtg
    43801 ccaaacgcct cctactcaac catatcagtg cccgtttcct ctcaaaagat ataagcaaac
    43861 tcaagaaaga cgctgccaca atttttgaaa atgtccatgt ggtcaaagac ttggaagaag
    43921 tggaaatcta gcagtcacag aaaggataag tatgcctact attctcatta cgggagctag
    43981 cggtggtcta gctcaagaaa tggtcaaact cctgcccaat gaccaactca tcttgcttgg
    44041 tagaaataag gaaaaattag cccaactcta cggaaattat tcccatgcag aattgattga
    44101 aattgatatt accgacgatt cagccctaga agctctggta actgatcttt atctccgcta
    44161 tggcaagatt gatgtcttga ttaacaacgc tggttacggg atttttgagg gatttgacca
    44221 aattgctgat aaagacattc accagatgtt tgaggtcaat acctttgccc tgatgaatct
    44281 gtctcgtcac cttgcggctc gtatgaagga aagcagcaaa gggcatatca tcaacatcgt
    44341 cagcatggca ggtctaatag ctactggcaa gtctagtctt tactcagcga ccaagtttgc
    44401 ggctattggt ttttcaaatg ctctgcgact cgaacttatg ccctatggag tctatgtgac
    44461 aacagtcaat ccaggtccaa tccgaacagg attttttgac caagctgacc cagatggaac
    44521 ttatcttaaa tcggttgacc gcttcctctt agaggcagat gcagtggcta aaaagattgt
    44581 caagattata ggcaaaaata aacgagaact caatctcccg attttgttga acctagccca
    44641 taagttttat actctctttc ccaagctagc tgataagttg gcaggggaaa cttttaatta
    44701 taagtaaaaa gaaccaatgt gcaggttgtt gctagcctac atattggttc ttatcatttc
    44761 tcaactatca aactgaactt cttctagtag atagtcgata aagcgttcgc ccatcttaga
    44821 taggctggtt ttctcatgct ggatatagac cagctcaatc gggtcatcaa tatccagtgg
    44881 gatagaaacg atattgtctc cgtttaggtt gctgttcaaa atccctgtcg caatggtata
    44941 accatccaaa ccaatcaaga gattaaagag ggtggcacgg tcactgacca caatggattt
    45001 tttgtggtgt tcttgagaaa gaatctcttc tgaaaagtag aaggagttgt gcgtcccttg
    45061 gtcatagctg aggtaaggga aattctccaa atcagacagt ttcaccttgt ctttctttgc
    45121 cagagggttg gtcttgctga caaagatatg cggttgcgct gtgaagagat ggtgggctag
    45181 caggtgattg tcatccagca tcttggttaa aacatcacgg ttgtaactgt ttaagaagag
    45241 gaccccgacc tcactgcgga agttcttgac gtcgtcgata atctcccaag tccgagtttc
    45301 acgaaggaag agttcgtatt tctccatatc gcttttcttg agcaaagaga caaaggcatt
    45361 gaccacaaag gcatagtgtt gagacgaaac gctaaatagt tcgcggtggg cgacaggatt
    45421 tttatagcgt tcctccagaa gctgggtctg ctcgacaacc tgacgggcat aagagagaaa
    45481 ctccatccca tcacgggtca aggtgattcc cttgggattg cggataaaga tctcaatgcc
    45541 catttcattt tccaaatctc gcactgcatt ggagagactt ggctgagtga taaagagttg
    45601 cttggctgcc tcattcatgg agccagtttc gacgattttg ataatataat gtaattgttg
    45661 aattctcatg tttttattgt accatacttg ccttagaatc gctaaagaag ataggaaaat
    45721 aaggagcatt gtgtgagtct cttcttgaaa aaaacacaaa attttgctag aatgagtctt
    45781 atgaaaacat tctatgatgt gcagcaattc ctcaaacgat ttggtattat tgtttacatg
    45841 ggaaaacgct tatatgatat tgaactgatg aagttggaac tatctcggat ttacgatgca
    45901 gggttgatgg ataaattaga ctatctagag gcagaagcag ttcttcgcag agagcacaag
    45961 gtagaattgg attatattga gaaaaatgga gaaaagaact aatggttact tggattttgt
    46021 gggcacttat actagcaatg ttggcgtgga tgggctttaa ctatcttcgt attcgccgtg
    46081 cggctaaaat tgtggacaat gaggagtttg aagccttgat tcgtacgggt caattgattg
    46141 atttgcgcga cccagcagaa ttccacagaa aacatatcct tggtgcacgc aatattcctt
    46201 caagtcagtt gaaaactagt cttgcagccc ttcgtaaaga taaacctgtc cttctctacg
    46261 aaaaccaacg tgcgcaacga gttacaaatg cagctcttta cttgaaaaaa caaggttttt
    46321 ctgagattta tatcctttct tatggcttgg attcttggaa agggaaagtg aagactagct
    46381 aaccttattt ccaaattagt cgaatgatag gatgaagcta ttgttttata gtataattaa
    46441 tttgtataaa atttaaggag ttcttagaac ataaaagaaa agaagaaaaa tccacttttt
    46501 gtgggtatct tgtcgattat tcttggtttg ttatttccaa ttgtaggcct gattttgggt
    46561 atcataggat tggtcttggc tatttcatac caaaaagagt cacaattaga ctataaaata
    46621 gaaaagattc ttaatatctt aggaattgtg atttctgtag ttaactggat tgtagcaatc
    46681 gccttaattt ttcgataaaa caaaaaaagc tttagtttta ggctctttgt caactgcagt
    46741 gggttgaagt cggctaagct cgagaaagga caaaattcgt cctttctttt ttgatgttca
    46801 gagcgataaa aatccttttt ttgaagtttt caaagttccg aaatccaaag gcgtttcg
//
LOCUS       DAVLTT010000012        43472 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLTT010000012 DAVLTT010000000
VERSION     DAVLTT010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.012"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(70..1737)
                     /locus_tag="VYN15_000700"
     CDS             complement(70..1737)
                     /locus_tag="VYN15_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV1452056.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(1740..2105)
                     /locus_tag="VYN15_000701"
     CDS             complement(1740..2105)
                     /locus_tag="VYN15_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1452057.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(2262..2450)
                     /locus_tag="VYN15_000702"
     CDS             complement(2262..2450)
                     /locus_tag="VYN15_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV1452058.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(2713..2911)
                     /locus_tag="VYN15_000703"
                     /pseudo
     CDS             complement(2713..2911)
                     /locus_tag="VYN15_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
     gene            complement(3166..4710)
                     /locus_tag="VYN15_000704"
     CDS             complement(3166..4710)
                     /locus_tag="VYN15_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV1452059.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            4923..5225
                     /gene="gatC"
                     /locus_tag="VYN15_000705"
     CDS             4923..5225
                     /gene="gatC"
                     /locus_tag="VYN15_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV1452060.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            5225..6691
                     /gene="gatA"
                     /locus_tag="VYN15_000706"
     CDS             5225..6691
                     /gene="gatA"
                     /locus_tag="VYN15_000706"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV1452061.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            6691..8133
                     /gene="gatB"
                     /locus_tag="VYN15_000707"
     CDS             6691..8133
                     /gene="gatB"
                     /locus_tag="VYN15_000707"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV1452062.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISNEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNTEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            8262..8822
                     /gene="efp"
                     /locus_tag="VYN15_000708"
     CDS             8262..8822
                     /gene="efp"
                     /locus_tag="VYN15_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV1452063.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            8844..9233
                     /locus_tag="VYN15_000709"
     CDS             8844..9233
                     /locus_tag="VYN15_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1452064.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            9226..9648
                     /gene="nusB"
                     /locus_tag="VYN15_000710"
     CDS             9226..9648
                     /gene="nusB"
                     /locus_tag="VYN15_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV1452065.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(9697..9933)
                     /locus_tag="VYN15_000711"
     CDS             complement(9697..9933)
                     /locus_tag="VYN15_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1452066.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(10415..10600)
                     /gene="briC"
                     /locus_tag="VYN15_000712"
     CDS             complement(10415..10600)
                     /gene="briC"
                     /locus_tag="VYN15_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV1452067.1"
                     /translation="MTGTETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(10758..11525)
                     /locus_tag="VYN15_000713"
     CDS             complement(10758..11525)
                     /locus_tag="VYN15_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV1452068.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(11522..12388)
                     /locus_tag="VYN15_000714"
     CDS             complement(11522..12388)
                     /locus_tag="VYN15_000714"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV1452069.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(12425..13792)
                     /gene="accC"
                     /locus_tag="VYN15_000715"
     CDS             complement(12425..13792)
                     /gene="accC"
                     /locus_tag="VYN15_000715"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV1452070.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(13804..14226)
                     /gene="fabZ"
                     /locus_tag="VYN15_000716"
     CDS             complement(13804..14226)
                     /gene="fabZ"
                     /locus_tag="VYN15_000716"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV1452071.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(14223..14708)
                     /locus_tag="VYN15_000717"
     CDS             complement(14223..14708)
                     /locus_tag="VYN15_000717"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV1452072.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(14711..15946)
                     /gene="fabF"
                     /locus_tag="VYN15_000718"
     CDS             complement(14711..15946)
                     /gene="fabF"
                     /locus_tag="VYN15_000718"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV1452073.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(15968..16699)
                     /gene="fabG"
                     /locus_tag="VYN15_000719"
     CDS             complement(15968..16699)
                     /gene="fabG"
                     /locus_tag="VYN15_000719"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV1452074.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(16733..17653)
                     /gene="fabD"
                     /locus_tag="VYN15_000720"
     CDS             complement(16733..17653)
                     /gene="fabD"
                     /locus_tag="VYN15_000720"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV1452075.1"
                     /translation="MTKTAFLFAGQGAQCLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEATPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(17646..18620)
                     /gene="fabK"
                     /locus_tag="VYN15_000721"
     CDS             complement(17646..18620)
                     /gene="fabK"
                     /locus_tag="VYN15_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV1452076.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(18739..18963)
                     /locus_tag="VYN15_000722"
     CDS             complement(18739..18963)
                     /locus_tag="VYN15_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1452077.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(19023..19997)
                     /locus_tag="VYN15_000723"
     CDS             complement(19023..19997)
                     /locus_tag="VYN15_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV1452078.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(19997..20431)
                     /locus_tag="VYN15_000724"
     CDS             complement(19997..20431)
                     /locus_tag="VYN15_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1452079.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(20525..21310)
                     /locus_tag="VYN15_000725"
     CDS             complement(20525..21310)
                     /locus_tag="VYN15_000725"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV1452080.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            21635..22999
                     /locus_tag="VYN15_000726"
     CDS             21635..22999
                     /locus_tag="VYN15_000726"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV1452081.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            23002..23373
                     /locus_tag="VYN15_000727"
     CDS             23002..23373
                     /locus_tag="VYN15_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV1452082.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            23586..24860
                     /gene="serS"
                     /locus_tag="VYN15_000728"
     CDS             23586..24860
                     /gene="serS"
                     /locus_tag="VYN15_000728"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV1452083.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKDLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(24885..25784)
                     /locus_tag="VYN15_000729"
     CDS             complement(24885..25784)
                     /locus_tag="VYN15_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV1452084.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLTE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(25894..26442)
                     /locus_tag="VYN15_000730"
     CDS             complement(25894..26442)
                     /locus_tag="VYN15_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV1452085.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(26660..27982)
                     /locus_tag="VYN15_000731"
     CDS             complement(26660..27982)
                     /locus_tag="VYN15_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV1452086.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(28073..28161)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(28325..30661)
                     /locus_tag="VYN15_000732"
     CDS             complement(28325..30661)
                     /locus_tag="VYN15_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV1452087.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGAALNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(30765..31313)
                     /locus_tag="VYN15_000733"
     CDS             complement(30765..31313)
                     /locus_tag="VYN15_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV1452088.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEDQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(31310..31612)
                     /gene="zapA"
                     /locus_tag="VYN15_000734"
     CDS             complement(31310..31612)
                     /gene="zapA"
                     /locus_tag="VYN15_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV1452089.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            31699..32571
                     /locus_tag="VYN15_000735"
     CDS             31699..32571
                     /locus_tag="VYN15_000735"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV1452090.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            32583..33197
                     /gene="lepB"
                     /locus_tag="VYN15_000736"
     CDS             32583..33197
                     /gene="lepB"
                     /locus_tag="VYN15_000736"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV1452091.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            33431..35797
                     /locus_tag="VYN15_000737"
     CDS             33431..35797
                     /locus_tag="VYN15_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV1452092.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGEQKRQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDAEFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASSHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDSNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(35845..37128)
                     /locus_tag="VYN15_000738"
     CDS             complement(35845..37128)
                     /locus_tag="VYN15_000738"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV1452093.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEEALYQDAMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEETYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(37927..39063)
                     /locus_tag="VYN15_000739"
     CDS             complement(37927..39063)
                     /locus_tag="VYN15_000739"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV1452094.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(39125..39562)
                     /locus_tag="VYN15_000740"
     CDS             complement(39125..39562)
                     /locus_tag="VYN15_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1452095.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(39564..41519)
                     /locus_tag="VYN15_000741"
     CDS             complement(39564..41519)
                     /locus_tag="VYN15_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1452096.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLSNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIVNEKIKKLEN"
     gene            complement(41543..43312)
                     /locus_tag="VYN15_000742"
     CDS             complement(41543..43312)
                     /locus_tag="VYN15_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV1452097.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGSIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNILLGVLVAAVVSFLIA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT        12785 a         9846 c         8260 g        12581 t
ORIGIN      
        1 acgaaatttg tcctttctcg agcttagctt tttttcaacc cactacagtt gacaaagagc
       61 ccattaatct tattccacac taaataggta tgggtaaaca ggttgttgac cttggtgaat
      121 ctcgacttca acgtcttcga attcttctac gatttcttga gcgatttcat tggcaagttc
      181 ttcgcttccg tcttcaccga catagaaggt tacgatttca ctgtcttcat ccaacatatg
      241 tttcaaggtt tcagtcaatg tttggtgcat atcagggttt gacacaagaa tttttccatc
      301 caccatacct agattatcgt tttcatggat ttctaagcca tcgatcgttg tatcacgcac
      361 ggctgttgtg acgcttccgc taacgacatc gctaagagca gctgtcatac gctcttgatt
      421 ttcttcaatg gacttgcttg gatcaaaggc aagaagactt gtcatacctt gaggaagagt
      481 gcgagcctct accactactg ctggttgctc caaaacttct gccgcagatt gagctgccat
      541 gaagatgttc ttgttgtttg gcaagaagat gatgttacgg gcattgacct gttcaacagc
      601 cttgataaag tcttctgttg aagggttcat ggtttgaccg ccttcgataa cataatccac
      661 gccttgagaa cagaagatat ctgctagacc tttaccagcc accacagcaa tcaaagcata
      721 ctctttttct tcagccgact tgataacttg agtagcttct ttctcaacct gtgcttcgtg
      781 ttggttacgc atattgtcaa cttttacctt gaccaagcta ccatatttga gaccttcttg
      841 cataacaagt cctggatctt ctgtatgaac atggactttg acaatttcat catcgttaac
      901 aacgaggaga gaatccccaa gctcatccaa gtagttacgg aattcatcgt agtcaaaatc
      961 tttagcataa gttggacctt gcttaagagc taccatgatt tcagtacagt aaccaaacgt
     1021 gatgtcctca gtcgctacgt gaccagctac agacttatga tgctctacat tgatcatctc
     1081 actcatgtta gcaggagtcg ctacaaagtc ctcagatgca atatattcgc cagtaagggc
     1141 tgaaaggaaa ccttcgtaga tgaagaccaa tccttgacca cctgagtcca caacgccaac
     1201 ttctttcaat actggaagca tgtctggtgt tttagctaga gctgttttag caccttccaa
     1261 ggctgcgcgc atgacttcaa cagtgtcatc tgtttgctca gcttttttct tagcaccgat
     1321 agcagctcca cgagaaactg tcaaaatcgt tccttcaaca ggtttcatca ctgccttata
     1381 ggcaacttcc acacctgatt ggaaggccag agccaagtct tgacctgtta actcgtcttt
     1441 atccttgata gcttgggaaa atccacggaa aagctgagat gtaatcactc ctgagttccc
     1501 acgcgcaccc atcaaaagcc ctttggcaag aatgctcgct acttctccaa ctgtagaagc
     1561 tggcttgtct gcaacttctt tagcaccatt ttcaatggtc attcccatat ttgtcccagt
     1621 atctccatct ggaactggaa agacgtttaa tgaattgaca tattcagctt gcttattcaa
     1681 gcgagttgat gcagcctgca ccatttcttg aaataagcta gtagtaattt ttgacacggt
     1741 tattctccta caactttgat attttgaatg tagacattta cagtctgagc agtaattcca
     1801 agctggtttt ccaagctaaa ggcaacacgc tcttgaatgt tttttgacac ttcactaatc
     1861 tttgttccgt agcttaacac ggtatataca tcaactgcaa tactgccatc ttcggctgcc
     1921 tttacgacga cacctttaga ataattttcc ttacctagca gggcttggaa attatctttg
     1981 agggcatttt tactagccat accgaccaca ccaaaaatct cagttgctgc tccacctacg
     2041 acggttgcaa tcacttcatc tgttagttcg atttgaccat cttttgtatt aatttttaca
     2101 gtcatccttt ttacctcaac tagttgatac tctattttat catatttcag cccaagtgta
     2161 aaagcagaat gatgtatcag cggatattta ctctattttt caaacgatgt tatacccaca
     2221 ataaaagaaa aaagacccta aggtctcctt tgcttttatt attaaacgcg ttcaacttta
     2281 cctgatttca aagcacgagc tgaagcccaa acttttttag gtttaccatc gataagaaca
     2341 gtaacttttt gaaggtttgg ttttacggca cgttttgttt ggttcatcgc gtgtgaacgg
     2401 ttgtttcctg atacagtctt acgacctgta aagtaacata ctttagccat tgtgttttcc
     2461 tcctattaga tctaatatag cggatgtgct agcaccacat accgtactat gttatcacac
     2521 tttcttgttt tttgcaaggg aattggaaga ttttttattt gtgtcttaaa tcaggtcttg
     2581 cgtgacattt tctgctctcc acatgccatt gttgattaac agaacaccag aattaaaatt
     2641 atgtgtataa aaatcatcat atgaaagtcc ctcaaagggg agacgataac ctttcagaat
     2701 actactgtca atctaaacat tcacaatctc actattcaaa gtctctagtc ttttttccat
     2761 caattggaac cattctcgcg gaaggtcatc attaaaaaca taaaacttaa gattataata
     2821 gatgaacaca aagagatttt attgttattt caactttatc catataagca ttatctgcac
     2881 ctaagacaat cgcttttttc tcttctttca ctctttatct catttctttt tattcccatc
     2941 atatgtttct acgtaaccat tattttcgcc cattcgttcg taaaaccata ccagtggaga
     3001 ttttagatga agtcccatta cggtttacaa tttttacatt acgacacgga gttttacaaa
     3061 tcgatttcat ttgccaaacg tagttagtaa ggcagttagc tagttcgcca aatagcgact
     3121 agcgtccaac aatttggaac tttagttcca attgttggta ctgagtcaca tcttctcctc
     3181 taactctacg tctggatact tgtccgcaaa ccagcggagg gcaaagtcat tttcaaagag
     3241 aaagactggt tggtcaaaac ggtctttggc taagatattg cgacttgacg acatccgttc
     3301 atccaagtcc tcaggcttga tccaacgaac ggtcttttta cccattgggt tcataactac
     3361 ttctgcattg tactcgcctt ccatgcggtg tttaaagact tcaaactgga gttgacctac
     3421 agcgcctagc atgtactcac ctgtttggta attcttataa agctgaatag caccttcttg
     3481 aaccaattgc tcaatcccct tgtggaagga tttttgcttc ataacattct tagcagaaac
     3541 tttcatgaaa atttcaggag taaaggttgg cagtggttca aattcaaact tgtttttacc
     3601 aactgtcaag gtatccccaa cttgataagt accggtatcg taaaccccga taatatcacc
     3661 tgccacggca ttgatcacat tctcacgact ttccgccata aactgagtaa cattagacag
     3721 tttagccccc ttaccagtac gagggagatt gacactcatg ccgcgctcaa attcgccaga
     3781 tacgatacgg acaaaggcaa tacggtcacg gtgacgaggg tccatgttgg cttggatttt
     3841 aaagacaaat cctgagaaat ccttgtcata aggatccaca atttcaccgt ctgttttctt
     3901 gtgaccatgt ggttctggag caaacttgag gaaggtttca aggaaggtct gcacaccaaa
     3961 gtttgtcagg gctgaaccga aaaagacagg cgtcaattct ccagccagaa tagcttcctc
     4021 tgaaaactca ttcccggctt catttaaaag ctcaatgtca tccttgactt gctcgtagaa
     4081 aggattgcta ccaaagagtt tgtccccgtc ttctagactg gcaaaacgct catccccttt
     4141 gtaaagctct aaacgttggt tatagaggtc atacaagccc tcaaaggctt tccccatccc
     4201 gataggccag ttcatagggt agctagcaat gcccaagatt tcttccaatt cttgcaagag
     4261 atccaaaggc tcacgaccgt cacggtccag cttgttcata aaggtaaaga ctggaatgcc
     4321 acgatgtttc acaacctcaa acaatttctt ggtttgagcc tcgatcccct tggcagagtc
     4381 cacgaccatg accgcagcat ccaccgccat caaggtacga taggtatctt ctgagaagtc
     4441 ctcgtgccct ggcgtgtcta agatattcac gcgcttgccg tcgtagtcaa attgcataac
     4501 agatgaagta acagaaatcc cacgttgctt ctcgatatcc atccagtcag atttagcaaa
     4561 agtccctgtt ttcttccctt ttaccgtacc agcctcacga atctcacccc caaagtagag
     4621 taactgctca gtgatggttg ttttccccgc gtccgggtgg gagataatgg caaaggtacg
     4681 acgtttctta atttcttctt gaatattcat aagttctctt tctttgattc tctatttttc
     4741 ttgtttcaat agctgagaat gatttttaca ttggatttta ccattccttt caacactcca
     4801 ttatatcgga ttttagcatt tttttcaatt tctatttctt ttcacttccc cctcccttat
     4861 ttataggaaa atatggtaaa atagaacaga ctaaaaatca tcatttcacg aaaggatgca
     4921 agatgaaaat tacgcaagaa gaggtaacac acgttgccaa tctttcaaaa ttaagattct
     4981 ctgaagaaga aactgctgcc tttgcgacca ccttgtctaa gattgttgac atggttgaat
     5041 tgctgggcga agttgacaca actggtgtcg cacctactac gactatggct gaccgcaaga
     5101 ctgtactccg ccctgatgtg gccgaagaag gaacagaccg tgatcgcttg tttaaaaacg
     5161 tacctgaaaa agacaactac tatatcaagg tgccagctat cctagacgat ggaggagatg
     5221 cctaatgact tttaacaata aaactattga agagttgcac aatctccttg tctctaagga
     5281 aatttctgca acagaattga cccaagcaac acttgaaaat atcaagtctc gtgaggaagc
     5341 cctcaattca tttgtcacca tcgctgagga gcaagctctt gttcaagcta aagccattga
     5401 tgaagctgga attgatgctg acaatgtcct ttcaggaatt ccacttgctg ttaaggataa
     5461 catctctaca gacggtattc tcacaactgc tgcctcaaaa atgctctaca actatgagcc
     5521 aatctttgat gcgacagctg ttgccaatgc aaaaaccaag ggcatgattg tcgttggaaa
     5581 gaccaacatg gacgaatttg ctatgggtgg ttcaggtgaa acttcacact acggagcaac
     5641 taaaaacgct tgggaccaca gcaaggttcc tggtgggtca tcaagtggtt ctgccgcagc
     5701 tgtagcctca ggacaagttc gcttgtcact tggttctgat actggtggtt ccatccgcca
     5761 acctgctgcc ttcaacggaa tcgttggtct caaaccaacc tacggaacag tttcacgttt
     5821 cggtctcatt gcctttggta gctcattaga ccagattgga ccttttgctc ctactgttaa
     5881 ggaaaatgcc ctcttgctca acgctattgc cagcgaagat gctaaagact ctacttctgc
     5941 tcctgtccgc atcgccgact ttacttcaaa aatcggccaa gacatcaagg gtatgaaaat
     6001 cgctttgcct aaggaatacc tcggtgaagg aattaaccca gaggttaagg aaaccattct
     6061 aaatgccgct aaacactttg aaaaattggg tgctattgtc gaagaagtca gccttcctca
     6121 ctctaaatac ggagttgccg tatactacat catcgcttca tcagaagctt catcaaactt
     6181 gcaacgcttc gacggtatcc gttacggcta tcgcgcagaa gatgcaacca accttgatga
     6241 aatctatgta aacagccgaa gccaaggttt tggtgaagag gtaaaacgtc gtatcatgct
     6301 gggtactttc agtctttcat caggttacta tgatgcctac tacaaaaagg ctggtcaagt
     6361 ccgtaccctc atcattcaag atttcgaaaa agtcttcgcg gattacgatt tgattttggg
     6421 tccaactgct ccaagtgttg cctatgactt ggactcactc aaccatgacc cagttgccat
     6481 gtacttggct gacctcttga ccatacctgt aaacttagca ggtctccctg gaatttcgat
     6541 tcctgctgga ttctctcaag gtctacctgt cggtctgcaa ttgattggtc ccaagtactc
     6601 tgaggaaacc atttaccaag ctgctgctgc ttttgaagca acaacagact accacaaaca
     6661 acaacccgtg atttttggag gtgacaacta atgaactttg aaacagtcat cggacttgaa
     6721 gtccacgtag agctcaacac caattcaaaa atcttctcac ctacttctgc ccactttgga
     6781 aatgaccaaa atgccaacac taacgtgatt gactggtctt tcccaggagt tctaccagtt
     6841 ctcaataaag gggttgttga tgccggtatc aaggctgctc ttgccctcaa catggacatc
     6901 cacaaaaaga tgcactttga ccgcaagaac tacttctatc ctgataaccc caaagcctac
     6961 caaatttctc agtttgatga gccaatcggt tataacggct ggattgaagt cgagctagaa
     7021 gacggtacga ccaagaaaat cggtatcgaa cgtgcccacc tagaggaaga cgctggtaaa
     7081 aacacccatg gtacagatgg ctactcttat gttgacctca accgccaagg ggttcccttg
     7141 attgagattg tatctgaggc agatatgcgt tctcctgaag aagcctatgc ttatctgaca
     7201 gccctcaagg aagttatcca gtacgctggc atttctgacg ttaagatgga ggaaggttcg
     7261 atgcgtgtgg atgccaacat ctcccttcgt ccttatggtc aagagaaatt cggtaccaag
     7321 actgaattga agaacctcaa ctccttctca aacgttcgca aggggcttga atacgaagtc
     7381 caacgtcaag ctgaaatact tcgctcaggt ggtcaaatcc gccaagaaac acgccgttac
     7441 gatgaagcta acaaagcaac catcctcatg cgtgtcaagg aaggggctgc tgactaccgc
     7501 tacttcccag aaccagacct gcctctcttt gaaatctcaa acgagtggat tgaggaaatg
     7561 cggactgagt tgccagagtt tccaaaagaa cgtcgtgcgc gttatgtatc tgaccttggt
     7621 ttatcagact acgatgctag tcagttgact gctaataaag tcacttctga cttctttgaa
     7681 aaagctgttg ccctaggtgg tgatgccaaa caagtctcta actggctcca aggggaagtc
     7741 gctcagttct tgaatactga aggtaaaaca ctggaacaaa tcgaattgac accagaaaac
     7801 ttggttgaaa tgattgccat catcgaagac ggtactattt catctaagat tgccaagaaa
     7861 gtctttgtcc atctagctaa aaatggcggt ggcgcgcgtg aatacgtgga aaaagcaggt
     7921 atggttcaaa tttcagatcc agctatcttg atcccaatca tccaccaagt ctttgccgat
     7981 aacgaagctg ctgttgccga cttcaagtca ggcaaacgta acgccgacaa ggcctttaca
     8041 ggattcctta tgaaggcaac caaaggccaa gccaacccac aagttgccct taaactactt
     8101 gcacaggaat tggcgaagtt gaaagaaaac tagacagaac aaaaccagcc ctaaggttgg
     8161 ttttttcttc tctcccaact cccaataact attttggctt tatttccaga gtattttatg
     8221 gtaaaatgaa gagtaataat atttattaaa gaggtaaaaa catgattgaa gcaagtaaat
     8281 taaaagctgg tatgaccttt gaaacagctg acggcaaatt gattcgcgtt ttggaagcta
     8341 gtcaccacaa accaggtaaa ggaaacacga tcatgcgtat gaaattgcgt gatgtccgta
     8401 ctggttctac atttgacaca agctaccgtc cagaggaaaa atttgaacaa gctattatcg
     8461 agactgtccc agctcaatac ttgtacaaaa tggatgacac agcatacttc atgaatacag
     8521 aaacttacga ccaatacgaa atccctgtag tcaatgttga aaacgaattg ctttacatcc
     8581 ttgaaaactc tgatgtgaaa atccaattct acggaactga agtgatcggt gtcaccgttc
     8641 ctactactgt tgagttgaca gttgctgaaa ctcaaccatc tatcaaaggt gctactgtta
     8701 caggttctgg taaaccagca acgatggaaa ctggacttgt cgtaaacgtt ccagacttca
     8761 tcgaagcagg acaaaaactc gttatcaaca ctgcagaagg aacttacgtt tctcgtgcct
     8821 aatctctaga aagaggtcat tctatgggaa ttgaagaaca acttggcgaa atcgttatcg
     8881 ccccacgtgt acttgaaaaa atcattgcta tcgctactgc aaaggtagag ggtgttcact
     8941 ctttttcaaa cagatcagtg tctgataccc tttcaaaact ttcactcggc cgtggcattt
     9001 atcttaaaaa cgtggacgaa gaactcacag cagatatcta tctctacctt gagtacggag
     9061 taaaagttcc taaggtagcg gttgctatcc agaaagctgt caaagatgcc gtccgtaata
     9121 tggctgatgt agaactcgct gctatcaata ttcacgttgc aggtatcgtc ccagataaaa
     9181 caccaaaacc agaattgaaa gatctatttg acgaggactt cctcaatgac tagtccacta
     9241 ttagaatcta gacgccaact ccgtaaatgc gcttttcaag ctctcatgag ccttgagttc
     9301 ggtacggatg tcgaaactgc ttgtcgtttc gcctatactc atgatcgtga agatacggat
     9361 gtacaacttc cagccttttt gatagacctc gtttctggtg ttcaagctaa aaaggaagaa
     9421 ctagataagc aaatcactca gcatttaaaa gcaggttgga ccattgaacg cttaacgctc
     9481 gtggagagaa acctccttcg cttgggagtc tttgaaatca cttcatttga cactcctcag
     9541 ctggttgctg ttaatgaagc tatcgagctt gcaaaggact tctccgatca aaaatctgcc
     9601 cgttttatca atggactgct cagccagttt gtaacagaag aacaataaaa agaaaaagtg
     9661 tttgatatct atcaaacact ttttctttgc ctcccactat ctaaaaaaat gataatagat
     9721 ataattgtaa acaaaaatcc agataggttt tgcatgattg agaaagttaa aaaaactatg
     9781 gcagagaatc gttaatctca gattgtcggt agaacgataa acaagggcaa aaaagaaacc
     9841 aatcagacta taatataata aactaattgg atctctgtga gatagtatca aatggctaat
     9901 cccaaagatg atagcagata ggataacatc caaataatac ttggactagg gaaagaaggt
     9961 gttcataaaa taccctctat caagagtctc ctcaaaaaca ggaccgatga ttacaggcag
    10021 gacaaaagat aagatagtcg ataaaaaggt tggttgtcca tttgaaagaa ccacggtaaa
    10081 atactcatca tgaatattcc tatgattaat caaatgagca tagcgtgccc aaaaattacc
    10141 gagaatctga taaaccacat aagttgcaaa taaggagaag acaaatgacc agtcccagct
    10201 ctttttcttt tttaacctcc aaattaatag aaaaggaaac ttcccactaa tcccactgtt
    10261 aaaataagag aatagacatc agctcctaac cctaaaatga tcgtcacata caatccaatt
    10321 gtttgtggta aataggtaga tagtaaaata ataagcaaaa atattccaaa ttgtcttagt
    10381 ttctttgtgt ttctcatcgt acttttttga aagattaccc tgttcggaag ccgtacttcc
    10441 aagcatctat ataagaatta agtgcccctt gcctcatata gggagcaaat tctctataat
    10501 ataaccatct actatatcca tcttcccaaa cagcaagacc acctgaagtt tgctccaagt
    10561 cctcagttga aataactgta aatgtttctg tacctgtcat tgcaagtacc ttcttaaaat
    10621 agattgttgt aggctcacat ttatagtata tttctttttt gtctatttta tagcccatct
    10681 cctcaactat caatttttca acctgaattg catttttcca taaaaaatga gacctttcta
    10741 gtcccattta gtcattctta gtattttcta aatcgttgat agcgttcttc cagcaactct
    10801 tctagcggtt tttgtgaaag tctagccagc tccgtttgga gttctttttt gacactctta
    10861 atcagttctt tactagaaag tcctacttca gaaatcacct tatccaccac gtccatttct
    10921 aacagttcat gcgaagtgat tttcatcagt tctgctgctt ccatggcgcg agtaccgtcc
    10981 ttccataaaa tggaagcaaa gccttctgga ctgagaatgg catagataga attttccagc
    11041 atccagacac ggtccgcgac agctagagcc agagccccgc ctgaaccacc ttcaccgata
    11101 ataatggcga taataggaac tttcaggtca ctcatttcca tgagattgcg agcgatagct
    11161 tccccttgac cacgttcttc tgctccgaca ccaggataag cacctgctgt attaataaag
    11221 gtcacaactg gacggccaaa tttctcagcc tgtttcatca accgcagtgc ctttcggtag
    11281 ccttctggat gtggttggcc aaaattccgt ttgaggttgt cttgcaaact cttgcctttt
    11341 tggataccaa ccactgttac agcttggtct ccaagccaac caataccacc aacaactgca
    11401 ccatcatcac gaaaagaacg gtcaccatgt aattggataa attcatcaaa aatgcctgtc
    11461 gcaaagtcca aggttgtcaa gcgactctgc tcacgcgctt ctctgactat ttttgcaata
    11521 ttcatctagg actccctcca tgcaatctga ctaggctagc aatcgtatct ggtaagtctc
    11581 ttcttttgac aatagcatcc acaaagccat gttctaatag gaattctgcc ttttggaaat
    11641 cctcaggcaa gctttcacga accgtatttt caatcacacg acgcccagca aaaccaacca
    11701 agctctgtgg ttcagccaga atgatatcgc cttccatagc gaaagaagct gtcacaccac
    11761 cagtcgttgg atctgtcaaa atggtcaggt aaaagagacc agcatttgaa tgacgtttaa
    11821 ccgccgcaga gatcttagcc atctgcatga gactcatgat tccttcctgc atacgggctc
    11881 caccagaggc tgtgaatagg acaactggca atttttcgac agtcgcatac tcaaacaaac
    11941 gagtgatttt ttcacctaca accgtaccca tagaagccat gataaagtta gaatccataa
    12001 tcccaagagc cacagtctga cctttaataa gagcagttcc tgtcacaacg gcttcatgca
    12061 gacctgtttt ttcacgcata gatgccagtt tcttttggta accagggaaa tgcaagggat
    12121 ccttgctttc aatccctgta aacaattctt tgaaggttcc catatcaatc gtcaaagcca
    12181 agcgttcttg ggcagaaata cgaaaggtat agctacagtg cggacagata cgttcacttc
    12241 ccagatcctt ctgatagatg gtatgcttac agcctggaca ctgggaaaat aattcatctg
    12301 gaacctctgg cttagcttga ggtttttccc taaccgaacg attgggattg attcgaatat
    12361 acttatcttt tttactaaat agagccattg attccccttt tcggtttaaa ctcttaaagt
    12421 cattttattc tttttcttga tatttaggta agaaggtttc catcaagaag gaagtatcat
    12481 aatccccagc aatgacattg cgatctgaaa tgaggtcaag ctggaaatct gcattggtct
    12541 gcactccttc aatctctaat tcatagaggg cacgttgcat tttcatcaag gcgtcaaaac
    12601 gattttcgcc gtgtactatg attttggcaa tcatactatc ataataaggc ggaatggtat
    12661 aacctggata aactgctgaa tccacgcgca agccaactcc accacttggc agatagagat
    12721 tagtaatctt acctggactt ggagcaaagt taaaggctgg gttttctgca ttgatacgac
    12781 actcgatggc atgaccgcgt aggacaatat cttcttgctt aacagacaaa ggctgacctg
    12841 ccgcaatgca aatctgttcc ttaacgatat caacacctga aacaaactct gttactggat
    12901 gttctacctg aacacgagta ttcatctcca tgaaatagaa attgctactt gcttcatcaa
    12961 gaagaaattc aatggttcct gcattctcat agccaacaaa ctctgccgct cgaacagcag
    13021 cagcacctat ttcatgacgc agcgtttttc cgattgcaat cgagggactt tcttccaaaa
    13081 ccttttggtt attcctttga agagaacaat cccgctcacc caagtgaatc acatgtccat
    13141 gctcatcacc taggatttga acctcaatgt gccgagctgg atagataacc cgttctatgt
    13201 acatggcacc attgccataa ttggccttgg cctcactaga ggcagtttca aaggcagaaa
    13261 cgaggtcatc tggtttttca accttacgaa tccctttacc acctccacct gctgaagcct
    13321 tgagcataac aggatagcca attttttcag caacaatcaa agcttcttca gagttatgca
    13381 cttctccatc tgaacctggt ataacaggca cacctgcttt aatcatctga gcacgcgcat
    13441 tgatcttatc ccccatcata tccataacat gaccagatgg accgataaac ttgataccta
    13501 cttcttcaca catggtcgca aatttggaat tttcactgag aaatccaaaa ccagggtgaa
    13561 tagcttctgc ctcagtcaag actgcagctg atagaactgc attaatattg agataagact
    13621 ctgttgcctt gccaggacca atacaaactg cttcatctgc caaaagcgta tgaagagctt
    13681 ccttatcagc agttgaataa accgctaccg tcgcaatccc caattcacgt gccgcacgga
    13741 taatacgaac cgcaatttca ccacgattgg caattaaaat ttttcgaaac atggagaacc
    13801 tccttagttc ccaattgcaa aagtaaggat accactggct gcaagcttgc catccacttc
    13861 agcctttgct tcaaccacag ctatggtgcc acgacgtttt acaaaagtcg ctgtcataac
    13921 caattggtcg cctggtacaa cttgcttctt gaacttaacc ttgtccatac cagcgtaaaa
    13981 gaccagtttt cctttatttt caggttttga taactccaac acaccagcag tttgcgccaa
    14041 ggcttccata atcagaacac ctggcataac tgggtattga ggaaagtggc cgttaaagaa
    14101 aggttcgtta atggtcacat ttttgatagc aacaatggta tcctcgctca cttccaagac
    14161 acggtccact agaagcatag gataacggtg gggaagagct tctttgattc cttgaatatc
    14221 gatcatttga tacgtaccaa tcctttacca aactcaacca tttcttcgtt agagacgaga
    14281 atttccgtta ccacaccatc cttaggagct gggatttcat tcatgacttt catggcttcg
    14341 ataattacca atgtttgacc ttttttgaca ctatcaccaa ctgtaacaaa ggcaggttta
    14401 tctggtccag cagccaagta aaccactcca acaagtggac tctctacaag atttccctca
    14461 gtagccacac ttgcttcagc tggagctgga acttcttctg ctacagtctc tgctggagca
    14521 gatgtaggag ctactggact cggtgttgct agaacgggtg ctggagcgac ttgagttgca
    14581 acttcaggca caggtcttgc ttcattcttg ctaaactgca actcatccgt cccattttta
    14641 taagaaaatt ctctcaaact tgactggtca aattgagtca tcaagtcttt aatatcgttt
    14701 aaattcatac ttatctattc tcccaacgtt tgaaagcaag aactgcattg tggcctccaa
    14761 aaccaaaagt atttgaaata gcgtatggaa tttctttctc caagccttgt ccataaacga
    14821 cattagcttc gatataatct gatacttcac ttgtcccagc tgtcattggt acaaagttat
    14881 ggcgcatagc ttcgatggtg acgatagctt ctactgcacc cgcagccccc agcaaatgtc
    14941 ctgtaaaaga cttggttgat gatacaggta cttccttacc aagaacagct acgatagctc
    15001 cactttctcc tttttcattg gcaggagttg acgttccgtg agcattgaca taggctactt
    15061 gctctggaga aatctcagct tcttccaagg ctagtttgat ggccttgata gctccctgac
    15121 cttctggatg tggagaagtc atgtggtagg catcacaagt atttccgtaa ccaaccactt
    15181 cagccaggat agtagctcca cgtttttcag cgtgttcaag actttctaaa accaacatcc
    15241 ctgaaccttc acccataaca aacccattgc gatccttatc aaatgggatc gaagcacgag
    15301 ttggatcctc tgtagtagag agagctgtta aggcttggaa accagcgatg gcaaaaggtg
    15361 tgatagaagc ttctgttcct cccaccaaca tcacatcttg gaaaccaaac ttaatggagc
    15421 ggaaggcatc cccaatcgca tcatttgatg aagagcaggc agtattgata gatttacaaa
    15481 caccgtttgc accaaaacgc atggctacat tcccagaagc catatttggt aaagcttttg
    15541 gaagagtcat tggtttgaca cgtttgggtc ctttttcatg aaggcgaagt acctgatctt
    15601 caatttcctt gattccacca ataccagatg caacgataac accaaaacga tccctattaa
    15661 gagcctctac atcaagattg gcatgattta cagcctcttg ggctgcatac aaggcatata
    15721 aagaatagtt atcaaaacgg ttggtatctt tttttacaaa gtatttatcg aacggaaaat
    15781 cttggatttc tgccgcatta tgcacatcaa agtcactatg atcaaatttt gtaatgccac
    15841 caatgccgat tttcccagtt gctaaactat tccaaaattc ttctggtgta tttccgattg
    15901 gagatgttac tccataacct gttaccacta ctcgatttag tttcattctt ttcacctcta
    15961 gctttcgcta catacttaag ccaccatcaa tggcaatcac ttgaccagtt agataatctt
    16021 ggcctgctaa aaatactgtc aaatctgcaa cctgctctgc ctgcccaaat tctttcatcg
    16081 gaatctgagc tagtgtagct tccttaatct tatctgataa gatagcggtc atatcagact
    16141 caatcattcc tggagcaatc acattgactc gtatattccg actagcgacc tcgcgtgcca
    16201 cagacttggt aaagccaatc aagccagcct tagaagcagc atagttagct tgaccaatat
    16261 tccccatcaa accaacaaca ctagacatat taatgatagc accttctctg gctttcatca
    16321 tcggtttcaa gactgattgt gtcatattaa aggcaccagt cagattgacc ttgagcactt
    16381 tttcaaaatc tgcttctgtc atcttgagca taagagtatc ttgggtaatc cctgcattgt
    16441 tgaccaaaac atctactgaa cccagttctg caatagcttg atcaatcata cgcttagcgt
    16501 ctgcaaaatc tgatacatct cctgaaatgg gaaccacctt gataccatag tttgaaaact
    16561 cagcgagcaa ttcttctgag attgccccac gactgtttaa gacaatgttg gctcctgctt
    16621 gagcaaactt gtgggcgatg gcaagaccaa ttccacgact cgaacctgta ataaagatat
    16681 ttttatgttc tagtttcatt tttttccttt caaaacttct acttatttta gtctattttt
    16741 ctaaaagtgc tactaaactc gcttgatctt ccacatgagc taagtgagca gtttgatcaa
    16801 tttttttaac aaaacctgac aagactttcc ccggtccaat ctcgataaag ttgcttatgc
    16861 ctgcttcttg catgacccca atactttcat agaaacgaac gggttccttg acctgacgcg
    16921 tcaagagctg agcaatgtcc tctttttgca tcacagcagc ttctgtattg ccgactaggg
    16981 gacaagtaaa atctgaaaaa cttacctgag ctagagtttc agctagtttc tggctagctg
    17041 gctcaaggag agcggtgtga aagggacctg acaccttaag aggaatcaag cgtttggcac
    17101 ctgcttcttg caaaagttca accgctcgat caactgcaac cacttctcca gcaatgacga
    17161 tttgtgcagg tgtgttatag ttggctggag taaccactcc aagttcagaa gctttttgac
    17221 aggcttcttc aatgacctct actggcgtat tgagaactgc taccatcttg ccagagtcag
    17281 caggagtcgc ttcttccata taggctccac gcttagctac caaggcaacc gcatcttcaa
    17341 aatccaaggc gccgcttgcc accaaggcag agtattctcc aagagacaaa ccagcaacca
    17401 tatcaggctg atagcccttt tcttgcaata aacggtagat agcaaccgaa gtcgctagaa
    17461 tggctggttg cgtatagcgg gtctgattga gtttgtcctc ttccgtatcg atgagataac
    17521 gcaaatcata accgagcacc tgactcgctc gatcaatcgt ttctttaaca atcggatact
    17581 gatcatagaa atcccgtccc atccctagac actgggcacc ttgaccagca aataaaaagg
    17641 ctgttttagt catttcttac aactcctgtc cagcgagagg cttcttcttg aattttctta
    17701 gcggctccgt aatacaaatc ttttaggatt tcttcagctg tttcttcttt agaaacaagc
    17761 cctgcgattt gacctgccat gacagagcca ccatccacat caccgtgaac aactgctttg
    17821 gctagggcac ctgctcccat ttgttcaaag atttctaaat caggatcttc ctgcttaaag
    17881 gcatcttttt cagccagttc aaaatctcta gtcaactgat ttttaatagc acgaacagca
    17941 tgaccaaagt gctgagctga aatcgtagtg tcaatatccc ttgcttttaa aattttctcc
    18001 ttgtagtttg gatgggcatt cgactctttt gcaactacaa accgtgtccc cacctgtaca
    18061 gcctctgcac ctagcataaa gccagccgca gcaccttcac catccgcaat tcctcctgca
    18121 gcaataacag gaatagatat agctgtggct acctgtcgca ccaaggtcat ggttgttaat
    18181 ttgccgatat gccccccagc ttccattcct tctgcaataa cagcgtctgc accgattttt
    18241 tccatgcgtt tagctaaagc gacactagga acaacaggaa taacgattat cccagcttca
    18301 tggaaacgtt ccatatactt gcttggattt cctgctcctg ttgtgacaac tttaacacct
    18361 tcttcaataa cgagatccac gatatcttcc acaaagggag ataagagcat gatgttgacc
    18421 ccaaagggtt tatcagtcaa tgatttgatt ttatcaatat tggccttgac aacttctttc
    18481 ggggcatttc ccccaccgat aattcctaat cctccagcct tggaaacagc ccctgccaaa
    18541 tcaccatcag caacccaggc catccctcct tggaaaatag gatagtcaat cttcaataat
    18601 tctgtaatac gcgttttcat agtgcctcca accttccttg cttacgtaat agttcgattt
    18661 caccataatt tgacagtcaa actattacct aaacaagagg gagtgggttt ctccctactc
    18721 cttctactaa tattctgctt attttgcttg ctcttcaacg taagcaacca agtcaccaac
    18781 tgttttcaag tcattttctg cttcgatttg gatatcaaaa gcatcttcga tttctgagat
    18841 tacttggaac aagtccaatg aatctgcgtc caaatcatca aaagttgatt caagtgttac
    18901 ttctgatgcg tcttttccaa gttcttcaac gataatttct tgtacttttt caaatactgc
    18961 catgatagga ctcctttaaa ataaatagtt tttttataac aatgtgttca ccacatgatt
    19021 acctaaattg taagaatgag cgtgccccag gtcaagcctc caccgaagcc tgatagaaga
    19081 acagtctggc taccatctaa agggatgaga ccttgttcta cacactctga aagtaaaatc
    19141 gggatactgg ctgcactggt attgccatat tccatcatat tggctggaag tttggctcgg
    19201 tcaacaccaa tttttctagc catcttatcc aaaatacggt cattggcttg atgaagtagc
    19261 agataatcca agtctgtcac ctctatagga gattcatcaa tagtctgctt gatagacttg
    19321 gctacatctc gaatggcaaa atcaaagact gtgcgtccat ccatcttcaa aaacgaatct
    19381 gcactttctt gatctgaaaa tggagaatgc aaacctgaat gcccataagt taaacactcg
    19441 ctgcgacttc catcgctatt gagactctca gctaagaaat gctcttgctc gctagcttct
    19501 aacaagacac caccagcacc atctccaaac aacacagctg ttgatcgatc cgaccaatcg
    19561 actgccttag agagggtttc actaccaatc accaagcctt tttgaaagcg accagaagcg
    19621 ataaactttt cagcagttga aagagcaaat acaaatccac tgcaagccgc ggttaagtca
    19681 aaagcaaagg ctttattagc gccaatatta gcttgaacac gagcagctgt agagggcatc
    19741 atcgaatctg gagtaatggt agctaggatg ataaaatcca gttcttctcc tgttattcca
    19801 gcttttgcca tcagtttctt agcaacctct gtagccaaat cactggtaga ttctgttctt
    19861 gaaatatgcc tttgtcgtat tcccgttcga cttgaaatcc actcatcatt ggtatccata
    19921 atctgagcca agtcgtgatt tgtaaccact tgctctggca cataatgagc aacctgactt
    19981 atttttgcaa aagccattat ttcaaatcct ccaaaaattg gtaaagatta gtcaagcctt
    20041 tacccatgac agcaatttct tcctcgctca tgccatcaat aattttttct accatggcct
    20101 tgtggaagcg tttatgcagt ctatgaatca agcgaccctt ctttgtcaaa tgcagatgca
    20161 ccacacgacg atcctgttct gaccgaactc gctcaatgta gcccttacgc tctaaattgt
    20221 tcaaacttgt cgtaacagtt ccaagagtta ccatcaactc ttttgacact tgacttggag
    20281 tcacatctgg agccttaccg atgacatcaa tcgtatgcat ttctttgatg gagatatcct
    20341 taaaacgact acctctcaag ttcacttcct caattacaag gacattgtta aatatagatg
    20401 ttaaatattc attgattcgt tggtagtcca tttttcatat ccctccttct tcaaaaaact
    20461 tttacaatca aaacatttga cagaaagaat tatatcaaaa ttcaaagaat gatgcaagta
    20521 ttttttattt tcctgtaaat ttaggtcttc ttctctccga atgagctcgc actccttctt
    20581 tgaaatcctc tgtttgagct aaggatttct gtaggttcag ttctaaagta gcgtaaccct
    20641 gccagtcttt aaattggctc tcccaaacca acttcttaat ggcagcatag gaattacttg
    20701 aagcacgtct taatttttta agaagctgtt ctctcgtctt ttcaagtttt tcagcttcag
    20761 aaacgcggta aaccaacccc cattctaggg ctttttctgc cgttaaagcc tctcctgtca
    20821 tagctaattg agcagcacgc gtcacaccga tactgcggct caagagatga attccccctg
    20881 catctggagc caaaccaaca ccaacaaagg cttggataaa cttagcctta tccgtcgcca
    20941 aacagaaatc tgccgcaaca gccatattcg ctgcggcacc tgcaacagca ccgtcaactt
    21001 ccattaaaac aggtttggct atttgcttga ttttataaga aatcgtattg accaactctg
    21061 cgatttttgt caatgatgga atatcatcct catccactgc ccgcttcatc tctaccaaat
    21121 ctcccccaac tgagaagacc tttccattgg cattgattaa gataaaatgc acagctggat
    21181 tttcttctgc caaagtcaga gcttctaaaa tctcctcaca catgggaata tgaaaaccat
    21241 ttgcgacctc aggacggttc aaggtaagga ttgccaagtc ctcttcaagc tgataaataa
    21301 tgtgttccat cagggctcct ttttatttta taagcagttt atactcttcg aaaatctctt
    21361 caaaccgcgt cagcttccat ctgcaacctc aaaacagtat tttgagctga cttcgtctag
    21421 cttcttagtt tgctctttga tttttattga gtgttaaatt atttcactgt caaagtatat
    21481 cttttttagg atcagaaagc aagaaaaaat cgactgaaag tgtctcagcc gataagaaag
    21541 gctcgcttta ggctagaaag catcttattt tcttcattga aaaaagcctt tctttctgct
    21601 ataatcgtat aaaatactta ctttaggagt tcttatgaaa gttgttaaat ttggaggtag
    21661 ttctcttgcc tctgctagtc aattagaaaa agttttaaac atcgtcaaaa gcgattcaga
    21721 gcgtcgtttt gtagtcgttt ctgcgcctgg taaacgcaat gctgaagata ctaaggttac
    21781 ggatgccctg attaaatact accgcgacta tgttgcgggt aacgatatta gcaagagcca
    21841 aagctggatt atcgaccgct atgctgctat ggttagtgaa ttgggactaa aaccagctgt
    21901 gctagaaaaa atttctaaaa gcattcacgc cttggccact cttcctattg aagaaaatga
    21961 atttctctac gatactttcc tagcagccgg tgaaaataac aatgccaaat tgattgctgc
    22021 ctactttaac caaaatggta tcgatgcacg ctatatgcac cctagagaag ctgggattgt
    22081 ggtcacaagt gaacctggtc acgctcgcat cattccatca agttatgaca agattgaaga
    22141 attgacaaac accaatgaag tccttgtcat tcctggtttc tttggtgtca ctaaggaaaa
    22201 tcaaatctgt actttctcac gtggaggatc tgatattaca ggttctatca ttgctgctgg
    22261 tgtcaaagcc gacctctatg aaaactttac ggacgttgat ggtatctttg cagcccaccc
    22321 tggtattatc caccaaccac actcgattcc tgagttgacc taccgtgaaa tgcgcgagtt
    22381 ggcctatgca ggcttctcag tccttcatga cgaggctctt cttcctgcct accgtggaaa
    22441 aattcctctg gttatcaaga ataccaacaa ccctgaccat ccaggtactc gtatcgttct
    22501 aaaacacagt aatgatgaat ttccagttgt gggaattgct ggtgactcag gctttgtcag
    22561 cattaacatg tcgaaatacc tcatgaaccg tgaggttgga tttggccgca aggttctgca
    22621 aatcctggaa gaacttaaca tcggttggga acatatgcca acaggtatcg acgatctttc
    22681 tatcattctc cgttctcgcc aactaactcc catcaaggaa gaagaaatcc tgcgtcagtt
    22741 ggttcaaaag gctaaagtag atcatgcaga aatcgaacac gacctttcta tcattatgat
    22801 tgttggtgaa aaaatgaaga gccacatcgg agtgactgct actgcgacac gcgctctatc
    22861 tgaaaacaaa atcaacatcc agatgatgtc tcaaggttct agtgaagttt ctattatgtt
    22921 tgttgtcaat aaagaccaag agaaagcagc aattaaagcc ctctacaatg ccttttttgg
    22981 agaaagtaag gaagactaag catggcccaa tcacttaaca aaacagtact cctcagtacg
    23041 acaggcactt cctacctctc tatcgctggg aaagttggga aattccttgt cggagatcag
    23101 gctttggaat tttacccaga tgtcaatgtc gaacaattta tccagattcc ttggagccat
    23161 atcaatcaga ttggagccaa tgtcactgga cgcaaaatca gccgccactt cgaagtcttt
    23221 acagacaaag gaaaattcct ctttgcttca aaagactcag gtgccattct caaaattgca
    23281 cgcgaaaaac taggcaatga caaggtcgtc aaacttccga ccctgattca gacaattagc
    23341 caaaaattta aaaatctatt tgcaaaaaag tagaaacttt agtataatca tagcaacgga
    23401 taagtaggtt atcttcttct ttcagaaagt ctgagggtgc tgcgagcaga taggagggat
    23461 aggtgaaatt ctaccgttag tgacaattac atacacaatc aagtgcacac ctgtgaagtt
    23521 ggatggaacc gtggccctgc cactccaacg ttttgtcagg gtgctttttt cataaaggag
    23581 ttcttatgtt agatatcaaa cgtattcgta cagattttga agctgtcgca gaaaaattag
    23641 ctacacgtgg tgtagatgct gctgtcttga atgaaatgaa agaaatcgat gctaaacgtc
    23701 gtaacatctt ggtcaaggtt gaaactctca aagcagaacg taacacagtt tctgctgaga
    23761 ttgcccaagc taagcgcaac aaggaaaata cagatgacaa gattgctgcc atgcaaaatc
    23821 tatctgctga ggttaaagcc ttggatgctg aattggcaga aatcgatgct aaattgacag
    23881 aatttacaac gactcttcca aatatcccag ctgacagcgt tcctgttggg gctgacgaag
    23941 acgacaatgt ggaagttcgc cgttggggta ctccacgcga gtttgacttc gaacctaaag
    24001 ctcactggga tctcggtgaa gaccttggta tccttgactg ggaacgcggt ggtaaggtaa
    24061 caggcgctcg cttcctcttc tataaagacc tcggtgctcg tttggaacgt gctatctaca
    24121 actttatgtt ggatgaacat ggaaaagaag gctatactga agtcatcaca ccttacatag
    24181 tcaaccatga ttctatgttt ggtactggtc agtatccaaa atttaaggaa gatacttttg
    24241 aactcagcga taccaacttt gtcttgattc caactgctga agttcctctg acaaactact
    24301 accgtgatga aatcttagac ggcaaagatc ttccaatcta cttcactgct atgagtccgt
    24361 cattccgttc tgaggctggt tctgccggtc gtgatacgcg tggcttgatc cgtttgcacc
    24421 aattccacaa ggttgaaatg gtcaaatttg ccaaaccaga agaatcttac gaagaattgg
    24481 aaaaaatgac agccaacgct gaaaacattc ttcaaaaact caaccttcca taccgtgtcg
    24541 ttgctctctc tactggagat atgggcttct cagctacgaa gacttacgac ttggaagtgt
    24601 ggattccagc acaaaacaat taccgtgaaa tctcaagctg ttcaaacaca gaagatttcc
    24661 aagcccgtcg tgcccaaatc cgttaccgtg atgaagcaga tggcaaggtg aaactccttc
    24721 ataccttgaa cggttctgga cttgcagttg gacgtacagt ggctgcaatt cttgaaaatt
    24781 accaaaatga agatggttct gtgaccatcc cagaagcact tcgtccatac atgggtggag
    24841 ctgaagtcat caaaccataa aaaataaggt ttagctattt ctagctagac cttttttcgt
    24901 aaccaaatca gataagcacc tagtacaaag aataaaatag ttaggcatat aatggtttca
    24961 gtcaatacca ggtaatccag aaatggaagt ttcaaaattc cctgagccat cttgagcgag
    25021 gtcgctgtga taatggttgg gaaggtgagg gctgagaagg ctggttgaaa accttgtttt
    25081 aaaatgttgg gcagacgagt taaaacaaag aaaaagaagg attgagaagc caaaatcatg
    25141 acaatcaaga cccaagtcgg caggctggtt cctcctactc gaactagaga agccaagagt
    25201 agagagaaag gagcacagta gattccttct tgtccaagca aggctagtgg gagtggatgt
    25261 ttctttaaat cgctataaat aaggggatag agatagaagg tcaagagaaa accaaaactc
    25321 aaggtcgcat aggcaatttc gataatacct accagaggat aggtcaaggc agccactgct
    25381 atccccacat agagaaccgt ccagcttgga gtggcatgaa ccctccgccc tggacaagca
    25441 aacttgatgg taaaaccagc aatcaaggtc aaatccaaga gaaatgaaaa ccaccaaatc
    25501 ccttgtgcta ccaaaggaag ataagagaat acgcgaaaga cataggtcga taaaatcatc
    25561 ccagccatag gaaaggttgc cattcctgac aaaagagggg gcttggtcaa ttcttgcttg
    25621 gtttctttcc aattaaagag atgcagaatt agaaagtaaa tccataaaac caaaccagtc
    25681 agactaaaaa gatgggatag aaccggcaac gtatctaaaa taagatttcc agctcctgcc
    25741 aaacctagca aacaacctga aaatactaag gggagttttt tcatcctaac ctccaataat
    25801 catgttagtt tcagtataac ataaaagcgc ttaaatgagg atttaaaaaa acgaagtccg
    25861 cttatttcag acttcatttt actcagatat gaattaggca taaggttgca attctggatt
    25921 aattggtgta ttagctaagt tgttggcata gttacagagg attgctaggc tgacaccaaa
    25981 aaccacatcc aaggcatttt gttgagtgta gccagcttct aaaaactcag acaaggcttc
    26041 atctcctaca cgacccttgg tattgataac tgccaaggta aacttagcta gggtatccaa
    26101 tttaggatct gtttcaattg gagtacgatt gcgaagagct tgaatcaagt catcattcat
    26161 ctggatttgt ttgatggaaa aggctgtgtg acctgcgaca cagaatgcac aaccattggt
    26221 cacggctgcc gtgatttgca ccacttcacg ctcaacgggt gtcaggctgt tgcgacggtg
    26281 gatagatgag acaatttggt aggcttctaa aacagtcggg gcattggcca agagaccgat
    26341 taggttggga atatagccat tgttgtcttt ttctactgtt tcaagaattt ctttcacttc
    26401 tgctggtgct gactctactg tatggatagt aaatgttgtc ataagatacc tcttttctta
    26461 ttattgacac taatattatt gaaaaatctt ataaaatcct gattcctaag tttatctaag
    26521 ataaagcttt attctctcat aagattttcg ttgttatatt agtttatcac acttccaatc
    26581 acttgcataa tatatattat atatcaggct gataaaaatt atttatagcc aaaaaaatca
    26641 cacgagctgt gtgattccat tatttgtcaa aatacttttt agtttcagca ataacgactg
    26701 gcgacaagac caagagggca atcaagtttg gcagagccat caaggcgtta acgatatctg
    26761 cgataatcca gaccatatcc aactcgataa atcctcctaa caagaccatg agcacaaaaa
    26821 ccacacggta gagccagata aagcgaaccc caaagaggaa ctcaaaacag cgttctccgt
    26881 aatagttcca acctagaatc gttgtaaagg caaaaagtac aaggaagatg gtcaagaggg
    26941 caggcccaaa gtgtgaaaag actgttgaga aagctgactg agtcaaggca accccattca
    27001 agtcaccact ccaaactcca gttaccaaga tggtcaaacc agttagagta caaatgatga
    27061 gggtatcaat aaaggttcct gtcatggaaa tcaaaccttg ctctactggt tcatttgtct
    27121 tggcagctgc agctgcaata ggagcagaac ccagaccaga ttcgtttgag aacacaccac
    27181 gcgccacacc attttgaata gccatccgaa cgctagcacc agcaaatcca cctaccgcag
    27241 caaggggact aaaagctgag gtaaagacta aagcgattgt accagggatt tttccgatat
    27301 taaagaaaat aactgtaaga gttcctaaga tataaatgat ggtcataaaa ggaacaacag
    27361 tagttgaaac cttagaaata gacttgagtc caccaaagac tgcaatcgct acaaagacag
    27421 acaagacgag agctgtgatg gctggcgaaa tcgtcgttgt attttggata gattctgcaa
    27481 tcgagttgac ttgggtgaag gttccgattc ccaagagagc aaccaatact cctgctactg
    27541 caaacaaaac agcaagtggt cgccactttt ctcccatccc tagaaggata tagtgcatgg
    27601 gacctcccgc tactgcacca tggtcgtcct tggtgcggta tttgatggcc aagagtcctt
    27661 ccgcatactt ggtagccatt ccaaagaaag ccgccatcca catccaaaat agagctcctg
    27721 gtccaccaac cttgatagcc gtcgcaactc ctatgatatt tcctgttcca acagttgatg
    27781 ccaaggctgt acacagagct gcaaaactgg atacatcacc atgtccctta tcctggataa
    27841 aaataagctg aaaggccttg ggcagacgca aaacctgcaa gagtcctagc cgcatggtta
    27901 ggtaaatccc tgttccgacc aataaaatca agaggggcgg tccccaagca aaatcatcga
    27961 ttgatttaag caattctaac atttccttct cctatcgttt caaccccaaa agaaagagca
    28021 catgcaagat acatgtactc tggaatgctt agataaatgc taaaaagcgg tctatcctag
    28081 ctctgtcctt ttacctgaga gtttgagcag ttgcctgcct tgccccttcg gtgcctttac
    28141 ggtctctcca gagttccgtc catttacagt catggaaaat caaacgattc cccacttcta
    28201 ttaaacttca ttcggtgttg gtatttaatt gattctaatt ttacaaaaaa tgttggcttt
    28261 tgtcaatgtg tttattagta aaaattagtt caacagtttt tactttataa agtccagaat
    28321 actgctatcc tttaaaagtg acaatagtcg caccactgcc tccagcattt tgtggggcat
    28381 agccgaaact cttgacatgt ttgtttcttt gcaagtattt ggtaactcct tcacggatga
    28441 ctcctgttcc gataccatgg atgatatcaa cttgagccat attgttaagc aaggcttggt
    28501 cgatgaaggt atctagctca ttcatggctt cttcatagcg cttgcctcga agatccagtc
    28561 tagcttgagg tcctcgccca gaagttcgtt ttacaacatt gacctgtttc ttcttgactg
    28621 gtttttcttg ctgggcttga acaagatcaa actctttctc ttccaaggtc atcttaatca
    28681 agccaacttg ggcttcccag cggccgtcct tgagttgact ggtcaaggta ccacgctgac
    28741 cataactgag aaccacgata tcatctccca cctttggagc tcgttttttc ttggcctttt
    28801 gaaggacctt gtttttagac aagtccactt tttcaggagc caattttttc aacttggcct
    28861 tggcttcaat gatttcgtgg ggcttgagtt gagatttact gtggagattt ttgagaatct
    28921 ggtcactttc acttagggcc atatccacaa tctcagcagc ctgttcacgc gccttgttaa
    28981 gctcggtttc cttttcacga ttaagctcgt tgtagagttt ttttagcgca cggttcatct
    29041 tgagattttc ttgctccacc tcacggatat tgtccaagcg tttgcggctt tccagcgtct
    29101 gctcttctaa ttgctcaatg atacgattga cgtcattgtc ctgatcgatc tgctgactag
    29161 catctcctac gataacttca gataggccta gacgtttggc aatttcaaag gcattacttc
    29221 ggccaggaac accctgcata aagcgatagg tcgggcgaag agttgcagta tcaaactcca
    29281 tactggcatt ttgcacaaag gctgtctcaa taccgtaggc cttgagttct ggatagtggg
    29341 tcgtcgccat ggtcttgatt tgacgcaggc gaaggtcctc cagaatagcc atggcaaggg
    29401 ctgctccctc ttggggatca gtaccagccc ccaactcatc caaaagtaag agtgaatgtt
    29461 ggttgacctt gccaagaata tccacgatat tggtcatatg gctagagaag gtagacaagc
    29521 tctgctcaat agactgctca tctccaatat cagcaaagat ttcttcaaaa ataccaacac
    29581 gacttccctt gtctgctaaa atcggcaatc ctgactgggc catgacctgt gtcaagccca
    29641 gagttttgag catgatggtc ttcccacctg tattgggacc tgtaatgaca atagctgtta
    29701 aatcttgacc aaaatagaca tcatttgcga cggcattttt gaccaaagga tggcagacat
    29761 ggagcagttg aatctcttga ttttctgaca gctgaggcac gactgcttgt ctttcttgga
    29821 taaatcgaac cttggcacga atcaagtcca gatgaccgat aatccaagcg tcattagcaa
    29881 tctcagccgc atgagggcgg acacgctcag aaatttcttg gagaatgcga agcatttcat
    29941 agcgctcatc tgctcgcaga ctagcaattt cttcgctcag tttgactacc tcacgtggtt
    30001 cgatatagac ggtgtttcca ctagcagaaa tatcatgaac gacacctgca atcttattgc
    30061 ggtaggtgtt tttgactggt aaaacctgac ggccatttct gctagcaaca attccttccg
    30121 tcaacatctg cgctttttgc ttgagtaagt cttgtaaaac atcgcgtacc tgactctcgc
    30181 tatcatgtat ttttcgacgg attcgcgcca attcttcact ggcaaaattt tcaatgaaac
    30241 ccgcatcatt aaaggcctga agatttcctt gtaattgcgg aaaatcatgt aatttctcaa
    30301 accaaagggc taattcttcc aaactgacat tttccagatt ggcgtaaaaa ctttgaagtt
    30361 ctcggctggc aagaagcacg cgtttcaaga gtaggaactc ctcgatattg agagccgctc
    30421 ccatctccaa cctcttgcag actcctgcaa tttccttagt tgagagaata gtaaaatgcg
    30481 gttgctcgac gaaaagagcc tgcatttcct tcatctcagc aaaagcctgt ttgattttat
    30541 ctgctttggc agtcggagcc agttgtctca attgctccaa gccctgctcg gtcaacaaat
    30601 gaggctcaaa caaggccttg accttatcga actctaatgt ttctaatatt ttcttattca
    30661 tctttatttc cttgtctttg aatgtctagg tgtggtagct ttttacattc tgatagattc
    30721 gagtcaaatc tgtaaacaaa gggctaggaa aactcctgcc ctttttatcc gattaaattt
    30781 gtcacccaga tttgtttgag ccaactggtt gttatcggta tgctctggat gatgtgtttt
    30841 gcgacgatac tcttttcaag aggattttgt ataactgcca tggggatggt cgccaagatt
    30901 gtcaaggcca tttgcaagac aaataaggtc accaacatgg acaagatacc tgctgaaact
    30961 tggaacaact taccacccag ttttttgcta ggaatcaagt gtaagagaag accaagcaaa
    31021 cgaccaatgc tatagacaat cccaaataca agcaagtagc cgatacctgc ataaaagacc
    31081 ttatccagct gaaagagttg atccgatggg aaaaagaaag tcccctgatc ttcctgcgaa
    31141 tttgcataag ggagcaataa atggaattgc tctccaagcc ccttataaaa ctggccagcc
    31201 ataaaagccg atgccatggc tgaaatcagg taataaacct gtaagagcag gcctctccga
    31261 tagccgatat aaaatcccca aaccaagacc aatagaagaa ggaatgaaat cataaggaat
    31321 cctcaatctt gctctgttct tgcttacaag tcacaagctt gtgacggagt tcttctagct
    31381 cttgctcctt atcgtcaaat tcaatctcac ggctgagctg agttgataaa cagttgactg
    31441 ccaacaaaag agcgattgtt tcatcatctg cgctaggcat ttgttcttta attgcttggt
    31501 atttttctgt cgcaacctta gcgatttcct ccataaaaag gttatcatgt tcgcttgtca
    31561 aggttaacga ttttttcccg aatgtaaatt tgaatcgatt tagatttgcc ataaaattca
    31621 cctcacgata ttataccaaa attcgctaat tttgtcagtt tttacaaatt ttactgcttt
    31681 tgtggtacaa tagaaactat ggcaagtatc acactcacac caagcgaaaa ggatattcag
    31741 gcttttcttg aacactatca aaccagtctg gctcctagca agaatcccta tatccgctac
    31801 tttttgaaac tacctcaagc aacggtttct atctatactt ctggaaaaat cttgcttcag
    31861 ggtgaagggg ctgaaaaata cgccagtttc tttggctatc aagctgtaga gcaaaccagc
    31921 ggacaaaatc ttcctttaat tgggacagat gaggtgggaa atggttccta ctttggtggg
    31981 cttgcagttg tggctgcctt tgtcacacct gaccagcacg actttttacg aaaactcggt
    32041 gtgggggatt ctaagactct gaccgaccaa aagatccgtc agattgctcc tattctcaag
    32101 gaaaaaatcc agcaccaggc actccttctc tcacccagca agtacaacga ggtcatcgga
    32161 gaccgctaca atgctgtttc ggttaaggtt gccctccata atcaggctat ctatctcctc
    32221 cttcaaaaag gtgttcagcc tgagaaaatt gtgattgatg cctttaccag tgctaaaaat
    32281 tatgacaagt acttggcaca agagaccaat cgtttcagca atcctatcag cttagaagaa
    32341 aaggctgagg gcaaatactt ggctgtcgca gtttcttctg tcattgcgcg tgatctcttt
    32401 ctggaaaatc ttgaaaatct gggacgagaa ctgggttatc agcttccaag tggagctgga
    32461 acggcttctg acaaggtggc tagccagatt ttgcaagcct atggtatgca gggactcaac
    32521 ttctgcgcta agctacactt taaaaatact gaaaaagcga aaaacgctta gaaaggtaag
    32581 ttatgaattt atttaaaaat ttcttaaaag agtggggatt attcctcctg attctgtcat
    32641 tactagcttt gagccgtatc tttttttgga gcaatgttcg cgtagaagga cattccatgg
    32701 atccgaccct agcggatggt gaaatcctct ttgttgttaa gcacctccct attgaccgtt
    32761 ttgatatcgt ggtggcccat gaggaagatg gcaataagga catcgtcaag cgcgtgattg
    32821 gaatgcctgg cgacaccatt cgttacgaaa atgataaact ctacatcaat gacaaagaaa
    32881 cggacgagcc ttatctagca gactatatca aacgcttcaa ggatgacaaa ctccaaagca
    32941 cttactcagg caagggcttt gaaggaaata aaggaacttt ctttagaagt atcgctcaaa
    33001 aagcccaagc cttcacagtt gatgtcaact acaacaccaa ctttagcttt actgttccag
    33061 aaggagaata ccttctcctc ggagatgacc gcttggtttc gagcgacagc cgccacgtag
    33121 gtaccttcaa agcaaaagat atcacagggg aagctaaatt ccgcttctgg ccaatcaccc
    33181 gtatcggaac attttaagaa acctaagagg ccgagaatca ccaatctcag cctcttcttc
    33241 tatcgtgaga agtgattgtt tattgacaaa tactcaatga aaatcaaaga acaaactagg
    33301 aagctagccg taggctgctt aaaacagtgt tttgaggttg cagatggaag ctgacgtggt
    33361 ttgaagatat tttcgaagag tataaaataa aaacaatccc aactctcacc tattcataca
    33421 aaggaatttt atggaagttt atttttcagg aaccattgaa cggattattt ttgaaaatcc
    33481 cagcaatttt tatcgcatcc tcctcctaga aatcgacgat acggacgcag aggattttga
    33541 tgattttgaa atcattgtca caggaaccat ggctgatgta attgagggcg aagactatac
    33601 tttttggggg caaattgtcc agcactccaa gtatggagaa caactgcaaa tcagtcgtta
    33661 tgatcgcgca aaaccaacta gtaagggctt ggtcaagtac ttttcaagta gccatttcaa
    33721 ggggattggt ctcaagacag ctcagaaaat cgtggatacc tatggcgaaa ataccattga
    33781 cgaaattttg caacacccag aaaagttaga aggcatcgca ggactctctg ccaaaaatcg
    33841 cgaggctttc gtctccactc tccgtctcaa ctacggtacg gagatggttt tggccaaact
    33901 agccaactac ggcattccca acaaactagc ctttcagatt caagactttt acaaggaaga
    33961 aacccttgat gtggttgaaa attatcccta ccagctggtt gaggatatca agggtttggg
    34021 ctttaccatt gctgaccaac tagctgagga actaggcatc gaaagtcagg ctcctgaacg
    34081 cttccgcgcc ggtctagttc acagtctttt tcaggcctgt atggaaacag gggacaccta
    34141 tgttgaagca cgggatttgc tggaacaaac ccttactctc cttgagtctt cccgtcccgt
    34201 ggaactagac cccagccaag ttgcccaaga gctctcctac ctgatcgaag aagacaaggt
    34261 tcagcagatt gataccaaga tctttgacaa cagcctcttt ttcgctgagg aaggtatccg
    34321 cagtcacttg attcgtatcc ttgaaaaagg agaacagaag agacaagatt tagaaactat
    34381 tcaaaagcat atcactactg tcgagcaaga actggggatt gagtatgata acattcaaaa
    34441 acaagctatt tgtgacgcta tccagaacaa ggtctttatc ctgacaggtg ggcctggtac
    34501 tggtaagaca actgttatca atggaatcat cgctgtttat gcccttttag aaggacttga
    34561 cttcaggaag aaaagcaatc tgcccattct tcttgctgct ccaactggtc gagctgctcg
    34621 tcgcatgaat gaattgacag gtttgcctag cgcgaccata catcgccact tgggaatgac
    34681 aggtgacgat gataccagtc atctggaaga ttacctagat gctgagttta tcatcgtgga
    34741 tgaattctct atggtagata cttggctggc caatcaactc ttctccaata tctcttctaa
    34801 cagtaagatc ctcatcgtag gtgacagtga tcagctacct tctgtcagtc ctggacaggt
    34861 tctagcggat ctgcttcata ttcctttgat tcctcagact cgcttggaaa aaatttatcg
    34921 acaaagcaaa gaatcaacca tcgtcaccct agctagtcag attcgacagg gcatcttgcc
    34981 agctgatttc acccaaaaaa aagctgaccg ttcctacttt gaaattgcta gtagccatat
    35041 tcctgccacc attgaaaaaa tcttaggtgc cgccctcaga aatggtattc ccgcccgtga
    35101 tatccaagtt ctggctccta tgtaccgagg gacggcaggg attgatgcta tcaatcagct
    35161 catgcaagac ctgctcaatc ccccacaaaa agatcaactc agttttgaag ctcctcagtg
    35221 tcactatcgt aagagagaca aggtcattca tttggttaac gatgctgaaa tcaatgtctt
    35281 taatggggat ttaggagcta tcacagacct gattcctggt aaatacaccg aatcgaaaca
    35341 agacgagatt gtcattgatt ttgatagtaa tgaagtctct tacccccgta acgaatggta
    35401 caagattcgc ttggcctatg ccatgagtat tcataagtct cagggaagtg agttcccagt
    35461 tgtcatccta ccgattacta gtgctagccg acgtatgctg gagcgaaatc tcatctacac
    35521 agccattaca cgtgccaaaa gcaaactcat cttactaggc gaattacaag ccttcgacta
    35581 tgctacccaa cacatcggaa ctgcccgaaa aacctatctg attgaacgct tcagtgatct
    35641 actggagaat gttgaagaaa agcaacaagc tgtctctgaa acagtcacat caagtgcctc
    35701 tgaacaatcc tacatcctaa ccgaagaaaa ctgggaccgc atcccagcca tgattgggat
    35761 tacagacaca gacctcaaag agatttttgg aaaatagtgc atcagaaaac ccaccaattc
    35821 aggtgggttt tctgtttatt aagattattt tactgttgct gtgcttgtga tcaattcaac
    35881 agcttttttg atagtgatat catgtttcaa catgtcagct gaaagcaagt tttgaacttg
    35941 tgcaacttcc atgttgtagt ctgctgccaa ttgctcaact tctttttgta tttcttcttc
    36001 tgaagcatca aatccttcag ctttggcaac tgcttcgata acaaggttag tcttagtacg
    36061 tgactcagct tctgcttggt attggttgtg aaggtcttct tgagtagttc cagtgatttg
    36121 gaagtacatg tcagggttga tcccttgacg ttgcaagttc ccaaggaatt catttactga
    36181 acggtgaact tcttcatgga tcatttcttc tggaagttct acgatttcag cgttttctac
    36241 agctgtatca attgctgcac cttcaactgc atctttgtaa gtttcttctt tagcagcagc
    36301 caattctttg cggtattttt ctttcaagtc agcaagtgtt tcaacttctt catcaatgtc
    36361 ttttgcaagt tcatcgtcaa gagctggaac ttctttagct tttacttcgt ggatagttgt
    36421 cacgaattta gcttctttac ctgcaaggtc ttctgcttgg tagtcttctg ggaatgttac
    36481 gataacatca acggtttcgc cagctgagtg acctaccaat tggtcttcga aaccagggat
    36541 gaattgacct gaaccaagtc caagtgagaa gttttcacct tttccaccgt caaattcaac
    36601 accgtcgata gaaccaacga agtcgatcac aacagtgtcg ccgttttcag cagcagcttc
    36661 cttgataacc aattcagcca ggttgttgcg ttcgcgttcg atacgctctt cgacatcagc
    36721 gtcagttact tctttttcta catcaactga tacttcaagg tttttgtagt cacccaattt
    36781 tacttcaggt tttgtaacga cttcagcagt gataacccag tcttgacctt tttccattga
    36841 agttacgtca atttttggtt gggcaaccac ttcaagacca gcttctttta cagctgcttc
    36901 ataagcgttt ggcaaaagtg cgttcattgc atcttgataa agagcttctt caccaaattt
    36961 ttggtcgaag ataggtcgtg gaaggtgacc tttacggaaa cctggaacat taagagattt
    37021 cttcactgac ttgaagacac ggtccaattc tggtttgatt tggtcttgag agatagtgaa
    37081 agtcaagaca ccacggtttg tttctttgtt ttcaaatgat acagacattc tgtcatttct
    37141 ccttaaaatt ttttaaatac agtctattat aacattttct ataaataaaa tctagactaa
    37201 tgcagccaat tatagacaac aagccttttt cctaactaaa acactcataa agtatagaca
    37261 attttagact actttggata tcttttggtt agtcattttc caaaactaat ttatctaatt
    37321 tttcagttat atagtatatt gaaactagaa tagtacatct ctacttctaa aacattttta
    37381 gaaatcgatt tgactgtcct gatcgatttg tcctgttctt gtttcatttt actatataga
    37441 tcgcattcga aagaattcgt tccaaaattg cttggttcgt tcttctcttg gaccactaaa
    37501 gaattgatgg gcattatttt tttcaacaat tttcccactg tccataaaaa taacatgatg
    37561 ggctacatct ctagcaaaac ctatctcata aagctgatca aaaactcaat ctgaggagaa
    37621 aatccaataa ggctttccat aataaaggac atcctatcaa gatttttgaa cacccgatag
    37681 gctgcctttt cccgattttg aagacttttt gtccagcttc ttttacctta taaataacaa
    37741 caaaaatcaa agacaagcta gaaagattac cgcagataac tcaaacagtg ttttgaggtt
    37801 gcagataaga ctgacggagt cagctcaaag cactgctttg aggttgtaga tagaactgac
    37861 gaagtcagta acatatgcct aagacaaagc gatgctaacc tgatttgaag agattttcga
    37921 aaaagattaa atatactcta caatttgctc aatcaattct tggtcgtcta aacctgtaac
    37981 ttgtataaca acatctttga ctgattgttt agccaacaat tcacctaatc gaatactttc
    38041 ttcatcattt acatcgcgat agtcaaaggc atagccaact gttttaagta ggtttttata
    38101 tgacaaactg agttctttca attcacgtat cggccggatg aatcgttcat tatagcctaa
    38161 ttttcggatt ggagtacgag ctacgcgact aacttcgtcc actatgaaag ggttttcaaa
    38221 ccgttctata atgactttgt gataattctc caattctttt ttatcaaagt tccatttggc
    38281 aatcaagaga ctccgaattt cagctaatac agattcaatc cgagatttga tattaggatt
    38341 ttgaagagct tccaaaattg tcttggcacc ataatgcgca ccaatgtaag ctgaagttgc
    38401 atgtccagaa ttgactgaaa aaagttttcg ctcaataaag ggttctaaat cttcttcata
    38461 atgcacatct tttagacgta aatctggatt tttaagacgc ttggtttcca cgacccattc
    38521 attaaagggc tcgaccacaa caaaaaggga atcttcgtga ctttgtgctg gaacaatcct
    38581 gtctactgca gcatttggaa aacctatgta gttatcagca aatgtcaaac cttccggact
    38641 taaatatttc ttgacttctt gataaagaaa ttgagacccg ccaatcatat tttcacaggc
    38701 cataacatcc aatacctgtg tattccctgc aactcggcga gcttcgattc ctttggctag
    38761 aagttcagcg ataaaaggga gtatattagg tccgattgca gtagtaataa tatccgtctt
    38821 ttgaatcgct tcaatgactt gctcaggatg ttctttgcta ttaatgccag ccacattagt
    38881 tacttctata cgagactgtc ctttctgtgc aatttcaatt tcatacttgc ccttttcatt
    38941 tagagcatga attatctgat tattgacatc cacaaaatca atatggaaac catttttaaa
    39001 tagaatttca cctataaaac cacgaccgat attaccggca ccaaaatgaa cagaatgttt
    39061 cattcaattt ctccttttcc tatttgaggg acatatatac tagatgacaa atgacgaaat
    39121 tcaattattc aacagcatca aataagcgca atacttcctc ttttgactga gcatctgcta
    39181 gtttaagaac attatccaca tctgcacaga agatagaaat tttctgaata atttctaagt
    39241 gttcattacc aataccagca ataccaaaaa gaaccgttgc cacttgaggg ttagatacat
    39301 tcccaaaatc aacccctcta gggacttgaa cgactgtaat accagactta aggacatcat
    39361 tttttgctgc atctgttcca tgcggtatgg cgataaagtt acccatgtaa acagatagct
    39421 ctttatctcg ctcaatcatg gcttcaatat agtcttcatt aacatatcca ccctcataaa
    39481 gaacttgccc acaataacaa atagcttcct ccttgttaga aaattgttta ttaagcttaa
    39541 tcaaatgttt ttcaagtttc atattagttc tccaatttct taattttttc gttaacaata
    39601 gtatttagca tctgataaat aatggattga tttcccgtct tgtaaatctc tgtataaaga
    39661 tgattttcaa taatcgactg actaatagct gtcattaaat ctctagcttc ctcgctagct
    39721 tctttagaca ttagcattag cagacacctt ttgacctctt cttcctctcg tttcattgac
    39781 aatgcggaga taggtagttt gagttcaaac atagtaaaac tatttgttgt tactttgcta
    39841 gactgactat gtaaaagcac cagaccagta ttaggaatag ccataggact attctggaag
    39901 tgagataaca attttcttgt taggtaatct ctgtcactca cattcttctg atattggatg
    39961 atttgttcta ccgtgtgctc aaatgattga ttattctcca attgaaccaa ctcaaattga
    40021 ctcaaaagct gactactaga tattaaataa tcttgcaagt cataactttt ctctggagcg
    40081 atagcatcac gcgcgacaat tgtacgatgt gcctgtacat actgaagtcg ttcctgtaat
    40141 tcaagcaatt ctttgacggt tggaaaacta gaaattacat cgatttcctg attactcagc
    40201 ggcttggtag ataaaatata atcatactga ctgagatcaa tactgtggta atctactaga
    40261 gactgaatat ctatcaactc tacaaaagga gcaacactct taattttact gactaataaa
    40321 tctctagtga cccgacgttc atccgttaaa agcaaaacac ggactggata aatctctgga
    40381 ctacggccta agctagagat aaaatgtagg gcaatcatgc catactcata ctctgtatga
    40441 agatatttcg gaaaaatatc attcactaaa agactgatga ctgtataaag aaatttattc
    40501 ctttcaacta aaatctggac agattctggc aaattttcac cctgaaaaag gatagggacg
    40561 cctaaactga gccgaatatg atggaaaaga aaattgaata aaaccttgtc cttaaaaaag
    40621 tcaatcttgg tatacatgga aaccgtatca atcagatttg aaatattgta gaaaaattca
    40681 ccatcaaatt tctccgtaaa gagcggattg tcctgacgtt taatgattaa ttcatccaag
    40741 atgctcgcaa aatagataat ttcctgaata ctataaaatt gtgcagtctg cttagagtaa
    40801 gtttgaaaaa ttttttgaga aatttccaaa gcctgcttac tagtattagg tgaattttca
    40861 atgttttgct cctgacctat aagagataac aagatcgcaa aaaacatctt catcctagca
    40921 tccatatctg gaaaacctga cagttgctta ttaacaatct gactggccag cctagttcta
    40981 tctgcttcta aaatatcaaa gctcccaaaa ttaccggttg aaaaatctgc tactgagata
    41041 cagtttgtca gtaaaatagc caaaaatctt ctcttaccaa ctgaatcacc agaaatccga
    41101 taaccttttt gtcgttcaat tttcagatca aagtctaaaa gacgcttatc aatatctgaa
    41161 atatcctgaa taatagttac attactgact ttcgtgcact cttgcaatgc ttcattggtg
    41221 acaaaaccgc tctcagtcag aaggcgatag gtaatcaact cttgtctttc ttggggacta
    41281 tactcaacta acacttcaag ttctgtcggc aaatcatcca actctccagt caaaatatag
    41341 tatttcccat gcttcgttat ttcgattcca tattgctcca tgctatctgt caaatctgat
    41401 aaagttcgat aaattgttct agatgaaacc tgtaagattt cagtcatatc ttgcattgaa
    41461 agcttcccta catgtaggaa agccttcaat aattgttctt ctcgtttggt taatagcatt
    41521 cgtaatttag aaacctctag ttctatttgt acattctagc agccattttg tcatattctg
    41581 gtgttgttac taaactatcc acaataagaa attgagaatt cggtgctgct tgctgcactt
    41641 ctgcctgtaa agaaatagtt gttacaatca ttatgttttt agaattaaat tcacctaatt
    41701 ctgaaatttt ggcagtagaa actggaatac gaatattctt gtttctaaag atagcccgaa
    41761 tcgtttcaca gcccatagtt gcagttccct gtgctttacc ataagcaact actacagcat
    41821 caatatggtt aaggtcaatt tcctgactat ctactggtgc tgaagttggt atatctcctt
    41881 caatttctgc tattggagaa gctcctgtta atgaagctac aatttcatca taacgagggg
    41941 acgctaagaa attatcaaca gaaacatgaa tagcacttgg actcttgtct ttagctcttg
    42001 gtgtcagttc ttcctgagta acaattaatg tttttggtgt atcaagcaaa tttgagattg
    42061 cctgattaga tactggaatc tctagacctg cttttttaac cttatctcga agaatactag
    42121 ctcccatagc agagcttccc ataccagcat cgcaggcgaa aatgattttt tccactgagt
    42181 ctgtcgaaac aactgcatca acagaagttg atactaactg acctttagac tgagccttag
    42241 ctgcttgggt agccgcctga gcagcttcga gcgaatcctc agttgacttg tctgcatgaa
    42301 gaataagggc tgctataagg aaagaaacaa ctgctgccac taaaacacct aaaagaatat
    42361 ttagatgggg ccaaacacct tttggcgccg tagccataat cgcaataata gaacctggtg
    42421 aagctggaga tttaagacca gcgtctaaga gttgaaaagt aaaagttcca gagatacctc
    42481 ctgccatagc agctaaaaat agagtaggct tcatcataac ataaggaaag taaatttcat
    42541 gaatccctcc gaagaaatga ataaccattg ccccccaaga agaagattta gcagaacctt
    42601 taccgaatac agcataagct aatagaattc ccaggcctgg tccaggatta gcttccaata
    42661 ggaagagaat tgacttacca gcttgagcta cctgttctac tcccagagga gtaaaaatgc
    42721 catgattgag ggcattattg aggaaaagga ctttagccgg ttcgatgata atattagcca
    42781 taggaaggag gcgagcattg acaatagcct caacaccatt cccaacagct ccagtaagag
    42841 tcgatacgac tggaccgatt gcgtagaaag ccaaaagcaa taatgcaaaa ccaacgagac
    42901 cagctgagaa gttattaact aacatttcaa atccgggacg aattttttct tggaacttct
    42961 catcaaattt cttgatagtc catcctccca gtgggcccat taccatagct ccgataaaca
    43021 taggaacact agaacctgtg attgcaccaa cagtagcaat agatcctaca acggcaccac
    43081 gttggccatg gatcatatat ccacctgtgt aaccaatcag gattggcaat aaatacgtta
    43141 acataggacc aacaacagta gctaactgtt catttggcag atagccatca gcgataaaga
    43201 gggcagtcaa tactccccaa gcaataaatg ctccaatatt gggcataacc atatttgaaa
    43261 gcgatgtccc tagtttttga accctgactt tcaatgatac tttttcttcc attagatcat
    43321 cctccttttc ttaaaactag tatatacaaa gttaaaaacc tttaaaacta aagttttgtc
    43381 acagattttg tgtcaaaaca ttacttttga tgaggctggg caaaaaggct taaaaattat
    43441 aaaacgcatc atatcaggtg tacatgaact ac
//
LOCUS       DAVLTT010000013        42977 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLTT010000013 DAVLTT010000000
VERSION     DAVLTT010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42977
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.013"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            10..825
                     /locus_tag="VYN15_000743"
     CDS             10..825
                     /locus_tag="VYN15_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1452098.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTNLESANIAAQKGT
                     VPESMVKEQLPKVQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(845..2116)
                     /locus_tag="VYN15_000744"
     CDS             complement(845..2116)
                     /locus_tag="VYN15_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV1452099.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            2258..2989
                     /gene="budA"
                     /locus_tag="VYN15_000745"
     CDS             2258..2989
                     /gene="budA"
                     /locus_tag="VYN15_000745"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV1452100.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            2999..3190
                     /locus_tag="VYN15_000746"
     CDS             2999..3190
                     /locus_tag="VYN15_000746"
                     /inference="COORDINATES: protein motif:HMM:NF021592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV1452101.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKRR"
     gene            3225..3752
                     /locus_tag="VYN15_000747"
     CDS             3225..3752
                     /locus_tag="VYN15_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV1452102.1"
                     /translation="MIYGLAMAAFFEETARLVFFKWLEKKRSLEKADALAYGLGHGGL
                     ELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQSLSVWQIYLLGFERILAL
                     GFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLSQVGWLTNPVLVEVILALEL
                     VLVAYGTKEIFCKKS"
     gene            3864..4814
                     /gene="murB"
                     /locus_tag="VYN15_000748"
     CDS             3864..4814
                     /gene="murB"
                     /locus_tag="VYN15_000748"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV1452103.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            4873..6030
                     /locus_tag="VYN15_000749"
     CDS             4873..6030
                     /locus_tag="VYN15_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1452104.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            6011..6817
                     /locus_tag="VYN15_000750"
     CDS             6011..6817
                     /locus_tag="VYN15_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1452105.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            6814..7587
                     /locus_tag="VYN15_000751"
     CDS             6814..7587
                     /locus_tag="VYN15_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1452106.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            7584..8654
                     /locus_tag="VYN15_000752"
     CDS             7584..8654
                     /locus_tag="VYN15_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1452107.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            8907..9146
                     /locus_tag="VYN15_000753"
     CDS             8907..9146
                     /locus_tag="VYN15_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452108.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            9421..9906
                     /locus_tag="VYN15_000754"
     CDS             9421..9906
                     /locus_tag="VYN15_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV1452109.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFQLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            9928..12546
                     /gene="alaS"
                     /locus_tag="VYN15_000755"
     CDS             9928..12546
                     /gene="alaS"
                     /locus_tag="VYN15_000755"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV1452110.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(12636..14090)
                     /locus_tag="VYN15_000756"
     CDS             complement(12636..14090)
                     /locus_tag="VYN15_000756"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV1452111.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            14269..15018
                     /locus_tag="VYN15_000757"
     CDS             14269..15018
                     /locus_tag="VYN15_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1452112.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCNRIAILKKGHLIYCGSVEN
                     LRKDHPDQSLESIYLSLAGRKEEVADASQGH"
     gene            14999..16633
                     /locus_tag="VYN15_000758"
     CDS             14999..16633
                     /locus_tag="VYN15_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452113.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLFMSINIAFRFPFEEMPSFFSTMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            17317..18480
                     /locus_tag="VYN15_000759"
     CDS             17317..18480
                     /locus_tag="VYN15_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV1452114.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            18477..19154
                     /locus_tag="VYN15_000760"
     CDS             18477..19154
                     /locus_tag="VYN15_000760"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV1452115.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLNFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            19144..19998
                     /locus_tag="VYN15_000761"
     CDS             19144..19998
                     /locus_tag="VYN15_000761"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV1452116.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNAAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQDQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            20017..21084
                     /locus_tag="VYN15_000762"
     CDS             20017..21084
                     /locus_tag="VYN15_000762"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV1452117.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            21094..22260
                     /gene="aroC"
                     /locus_tag="VYN15_000763"
     CDS             21094..22260
                     /gene="aroC"
                     /locus_tag="VYN15_000763"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV1452118.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDVEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            22270..23373
                     /locus_tag="VYN15_000764"
     CDS             22270..23373
                     /locus_tag="VYN15_000764"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV1452119.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            23384..23722
                     /locus_tag="VYN15_000765"
     CDS             23384..23722
                     /locus_tag="VYN15_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV1452120.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKTVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            23814..25097
                     /gene="aroA"
                     /locus_tag="VYN15_000766"
     CDS             23814..25097
                     /gene="aroA"
                     /locus_tag="VYN15_000766"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV1452121.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKIIVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            25090..25566
                     /locus_tag="VYN15_000767"
     CDS             25090..25566
                     /locus_tag="VYN15_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV1452122.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDTNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRHVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            25563..26411
                     /gene="pheA"
                     /locus_tag="VYN15_000768"
     CDS             25563..26411
                     /gene="pheA"
                     /locus_tag="VYN15_000768"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1452123.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFDNITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            26408..27682
                     /gene="psr"
                     /locus_tag="VYN15_000769"
     CDS             26408..27682
                     /gene="psr"
                     /locus_tag="VYN15_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV1452124.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            27961..28806
                     /locus_tag="VYN15_000770"
     CDS             27961..28806
                     /locus_tag="VYN15_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1452125.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKKT
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDTVIADMDKSYTEYK
                     GEYGG"
     gene            28796..29899
                     /locus_tag="VYN15_000771"
     CDS             28796..29899
                     /locus_tag="VYN15_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1452126.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            29901..30887
                     /locus_tag="VYN15_000772"
     CDS             29901..30887
                     /locus_tag="VYN15_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1452127.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            30903..32336
                     /locus_tag="VYN15_000773"
     CDS             30903..32336
                     /locus_tag="VYN15_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV1452128.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLWV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQAEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            32365..33399
                     /locus_tag="VYN15_000774"
     CDS             32365..33399
                     /locus_tag="VYN15_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1452129.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            33599..34336
                     /gene="mecA"
                     /locus_tag="VYN15_000775"
     CDS             33599..34336
                     /gene="mecA"
                     /locus_tag="VYN15_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV1452130.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            34487..35773
                     /locus_tag="VYN15_000776"
     CDS             34487..35773
                     /locus_tag="VYN15_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV1452131.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGSIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            35775..36644
                     /locus_tag="VYN15_000777"
     CDS             35775..36644
                     /locus_tag="VYN15_000777"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV1452132.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            36720..36797
                     /locus_tag="VYN15_000778"
                     /pseudo
     CDS             36720..36797
                     /locus_tag="VYN15_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            36939..37877
                     /gene="msrB"
                     /locus_tag="VYN15_000779"
     CDS             36939..37877
                     /gene="msrB"
                     /locus_tag="VYN15_000779"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1452133.1"
                     /translation="MAEIYLAGGCFWGLEAYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            37935..39659
                     /locus_tag="VYN15_000780"
     CDS             37935..39659
                     /locus_tag="VYN15_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1452134.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIREDLPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            39661..41409
                     /locus_tag="VYN15_000781"
     CDS             39661..41409
                     /locus_tag="VYN15_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1452135.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFFLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            41711..42970
                     /locus_tag="VYN15_000782"
     CDS             41711..42970
                     /locus_tag="VYN15_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV1452136.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPSGVDIQQIYQAVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
BASE COUNT        12338 a         8215 c         9709 g        12715 t
ORIGIN      
        1 tgtttattta tgaaatcaaa aaaatggata tttgttttat gtaattttct tgcaagtttc
       61 ttcttagtag cttgccagtc aggttctaat ggttctcagt cagctgttga ggccattaag
      121 caaaagggga aattagttgt ggcaaccagt cctgactatg caccctttga atttcaatca
      181 ttggttgatg gaaagaacca ggtagtcggt gcagacatcg acatggctca ggctatcgct
      241 gatgaacttg gggttaagtt ggaaatctca agcatgagtt ttgataatgt tttgaccagt
      301 cttcaaactg gtaaggctga cctagcagtt gcaggaatta gtgctactga cgagagaaaa
      361 gaagtctttg atttttcaat cccatactat gaaaacaaga ttagtttctt ggttcgtaag
      421 gctgatgtgg aaaaatacaa ggatttaact aacctagaaa gtgctaatat tgcagcccaa
      481 aaagggactg ttccagaatc aatggtcaag gaacaattgc caaaagttca attaacttcc
      541 ctaactaata tgggtgaagc agtcaatgaa ttgcaggctg gaaaaataga tgctgttcat
      601 atggatgagc ctgttgcact tagttatgct gctaaaaacg ctggcttagc tgtcgcaact
      661 gtcagcttga agatgaagga cggcgacgcc aatgccgttg ctcttagaaa aaatagtgat
      721 gatttgaaag aagtggtaga caaggtcatc caaaaactta aggatgaagg aacttaccaa
      781 agctatcttg aaaaagcagc aagtctaact gaagttgaag aataagaaaa agcagagttg
      841 gatgtcattc caattctgct tttaaatagt ttaaaacatt ttccagattg tctagggaca
      901 ccttggcaaa ttgataagga caggtgctta aataggcctc ttcaaagaag tccaagccca
      961 gttgactgtg tttgagactg gcgattttag gatactgtct caggtctagc aataaaccat
     1021 cgtgtagggg ataatgagga aggggacaag gtgttttagt tatcctttcc tcgatttgtt
     1081 tttggtaaga ttcatgattg gtcaagcgag ccaaacgatt tttttcaaac aattgactgt
     1141 caatatagag tgacagggcc ttttgcataa tgaggttgct gtcgtagtct aggatatttt
     1201 tgtaggccac aaatgcttct ttgatagcat ttggaagaat gagtgctgta atacgaaggg
     1261 caggaaaaag gctggtcgag aaggacttga tataaatgac atgctcctct gtatcaagat
     1321 agtggaaggt ttggcccttc ttggagtcca aatcacccag ataatcgtcc tctacgatat
     1381 agacatcata cttggcagct aagttaagaa tagatcgttt gtcttgctca gaataggaat
     1441 gtcccagagg atagtgaaat ctaggaatgg tgtagaaaaa tttaattttt cctgttttga
     1501 agtggccttc cagctcctcc aagtcaatcc catcaatgcc tcgttcaatc gtttgatagt
     1561 ccagcccctg tgcaatcaag aggcgattca tccgatggta ggttggctgt tccaccaaga
     1621 tttccttggc ttgtctagga aaggatattt gagagaggat aaacaaggct tgttgggttc
     1681 cagaagtcag tactagttgg ttagccttgc agtagagagc ttgctcaaag aggagtttgt
     1741 gaatggactg tcttaggtct tctaatcctt cttgattgtc atagtagttg aagaggtagt
     1801 tttctcggcc aatcaaggtt tcattgacac agagtcggaa atcgtcatag gcactggcat
     1861 gttcgtcggt aacctcgatt tctaggtctt gatgttgccc ttgttctaat acatagtagc
     1921 cactctgagg cttggcatag aggtattgtt cgtgccgtaa ttccagcagg gctcgttgaa
     1981 tggtgtcctt gctgcagtga aagtcaaggc tcagttgacg gatagaaggc aggcgactac
     2041 ccgtcggaaa tcgttcagac tcgataccat ttttcagata ggaaacgacc tctttgtact
     2101 tgctttgttt cttcattcca gacctccctt gattttgtta cattgtaccc ttttttttcc
     2161 ttcttggcaa tgtctagagc gtttctctcg ttcacatcta ggggcaaatg tggtatactt
     2221 aggagtaaga tttatagaat aacagacaag aaagtgaatg gataagaacg tgcaggaacc
     2281 agtgaaatta tttcaataca atactcttgg agccttgatg gctggccttt atggtggtac
     2341 tatgacagta ggagaattgc tagaacatgg tgaccttggt ttgggaacct tggattccat
     2401 tgatggggaa ttgattgtct tggatggcaa ggcttatcag gccaaagggt caggagacca
     2461 gccagaaatt gtggaagtgt caccagatgc ccttattcct tacgctgcag tggtaccgca
     2521 tcaggcagag gtcattttcc gccagcgctt tgagatgaca gacaaggaat tgaaagaacg
     2581 aattgagtct tattatgatg gggaaaatct tttccgttct atcaagattc ggggggaatt
     2641 ttcacatatg catgtgcgta tgattcctaa gtcaacaccc gataccaagt ttgctgatgt
     2701 cgcaacccat caaccggaat atagtcgtga caatgttgcg gggactattg ttggtttctg
     2761 gacgcctgag attttccatg gggtcagtgt ggcaggctac catctgcact tcatatcaga
     2821 tgatttgacc ttcggtggac atgtcatgga ttttgtcatc aaggaaggca ttatcgaggt
     2881 gggagcagtt gaccagttgg accaacgttt cccagtccaa gaccgtcaat acttgtttgc
     2941 taagttcaat gttgacgaga tgaaaaaaga tattgaaaag gcagaatagg agaagaaaat
     3001 gaccattcat atcattatta ccatgttgct gttgctagct tttctgatag gaagcatttg
     3061 gtttgccaaa aagaaatacc agattaatct agctgtcttg ggcttgggtg cagtcgcttt
     3121 ctttgtctct tcgcagattt tggaaaaact ggtgcatatc ttgattttgc atcctcaaaa
     3181 aagacggtag tattgccctc ttgcaagatc acccgcttgt ctatattatc tatggcctag
     3241 ctatggcagc attttttgag gaaacggctc gtcttgtttt cttcaaatgg ttggagaaaa
     3301 agagaagttt ggaaaaggca gacgccttgg cctatggact ggggcatggt ggcttggagt
     3361 tgatttttct aggccttact agtttactca atctttacat tgttctttcg gcagttcaaa
     3421 ctcagaatcc acaggttatg caattactgt ctgaaaatat gttaaaaacc attcagtcac
     3481 tttcggtctg gcagatttat ttgcttggtt ttgagcgaat cttggcgctt ggtttccaat
     3541 tacttttgac agtttgggtt taccaagctg ttcgccagaa gaaatggatt tatctcctag
     3601 cagcctatgg cttgcatgcc ttctttgatc tggcaccatc tctttcccaa gtaggctggt
     3661 tgacaaatcc agtcttggtt gaagtgattc tagcactgga gctcgttctg gtcgcctatg
     3721 gaaccaagga aatcttttgt aaaaaatcat aaaaaggggg aaacctcttt ttcttatgca
     3781 aaatccaaac aaggtatttt tatggtcgtc aaatgtctct aaaaatggta taatggaatg
     3841 aattttgtaa aaggaagagt gacatgtctg taagagaaaa aatgcttgaa atcttagaag
     3901 gaattgatat ccgttttcag gaacccttgc atagctatag ttatacaaaa gtaggtggag
     3961 aggctgatta tttggtcttt ccacgaaatc gttttgagtt ggctcgcgtt gtgaaatttg
     4021 ccaaccaaga aaatatccct tggatggttc ttggcaatgc aagcaatatc atcgttcgtg
     4081 atggtgggat tcgtggattt gtcatcttgt gtgacaagct caataacgtt tctgttgatg
     4141 gctataccat tgaagcagaa gctggggcta acttgattga aacaactcgc attgccctcc
     4201 gtcatagttt aactggcttt gagtttgctt gtggtattcc aggaagcgtt ggcggtgctg
     4261 tctttatgaa tgcgggtgcc tatggtggcg agattgctca catcttgcag tcttgtaagg
     4321 tcttgaccaa ggatggagaa atcgaaaccc tgtctgctaa agacttggct tttggttacc
     4381 gccattcagc tattcaggag tctggtgcag ttgtcttgtc agttaaattt gccctagctc
     4441 caggaaccca tcaggttatc aagcaggaaa tggaccgctt gacgcaccta cgtgaactca
     4501 agcaaccttt ggaataccca tcttgtggct cggtctttaa gcgtccagtc gggcattttg
     4561 caggtcagtt aatttcagaa gctggcttga aaggctatcg tatcggtggc gtagaagtgt
     4621 cagaaaagca tgcaggattt atgatcaatg tcgcagatgg aacggccaaa gactacgagg
     4681 acttgatcca atcggttatc gaaaaagtca aggaacactc aggtattacg cttgaaagag
     4741 aagtccggat cttgggtgaa agcctatcgg tagcgaagat gtatgcaggt ggttttactc
     4801 cctgcaagag gtagtgggga cctgacagag ccccgatcgg ttaatctatg aaaaagaagg
     4861 aatttatgcc aattgaaaaa accaattatc gaattcaaaa acgtctctaa agtttttgaa
     4921 gacagcaaca ccaaggttct caaagacatc aactttgagt tggaagaagg gaaattctac
     4981 acccttctag gtgcatctgg ttcggggaaa tcaactatcc taaacattat tgcaggttta
     5041 ctggatgcga cgacaggaga tatcatgcta gacggtgttc gtatcaatga tattccaacc
     5101 aacaagcgcg acgtacatac cgtcttccaa tcctatgcct tgttcccaca tatgaatgtg
     5161 tttgaaaatg ttgcctttcc acttcgcttg cgtaaaattg ataagaaaga aatcgagcag
     5221 cgtgtagcgg aagttctcaa gatggttcag ttggaaggtt atgaaaaacg ttccatccgc
     5281 aaactttctg gaggacaacg tcagcgtgtg gccatcgccc gtgctatcat caaccaaccc
     5341 cgtgtggtct tgttggacga gcctttatca gcgctggact tgaaattgag aacagacatg
     5401 cagtacgaat tgcgtgaatt acaacaacga ttgggcatta cctttgtctt tgtcactcac
     5461 gatcaggaag aagctcttgc catgagtgac tggattttcg ttatgaatga tggcgagatt
     5521 gtccagtctg gaacccctgt ggacatctac gatgagccaa tcaaccactt tgttgccact
     5581 tttatcgggg agtcaaacat cttgccaggt accatgattg aggactactt ggtcgaattt
     5641 aacggcaaac gctttgaagc ggttgatggt gggatgaagc caaatgaacc tgttgaggtc
     5701 gttattcgtc cagaggactt gcgcattacc cttcctgaag aaggcaaact ccaagttaag
     5761 gtcgacaccc agctcttccg tggagttcat tatgaaatta tcgcctatga cgaacttgga
     5821 aatgaatgga tgatccactc aacccgtaag gccatcgtgg gtgaggaaat cggtctggac
     5881 tttgaatcag aagacatcca catcatgcgt ctcaatgaaa ccgaagaaga gttcgatgct
     5941 cgtatcgaag aatacgtgga aatcgaagag caagaagcag gtctgatcaa tgcgatcgag
     6001 gaggaaagag atgaagaaaa caagctctaa actctttgta gtgccctaca tgctttggat
     6061 tgccctcttt gtattggcac ccttggtctt gattttcgga caatcctttt tcaacattga
     6121 aggccagttt agtttagaaa attataaatc ttactttgcg tcacaaaact tgacctacct
     6181 caaaatgagt ttcaactcag tgctttatgc aggcattgtg acctttgtga ccttgcttat
     6241 cagctatcca acagccctct ttttgacccg tctcaagcac cgtcaactct ggctcatgct
     6301 gattatcctt cctacctgga tcaatttgct ccttaaagcc tatgctttta tcgggatttt
     6361 tggtcaaaat ggctctatta accaattctt ggaatttatc ggaattggtt cacaacagtt
     6421 gctttttacc gatttttcct ttatctttgt cgcaagctac atcgagctcc cctttatgat
     6481 tttgccgatt ttcaatgtct tagacgatat ggataataat ctcatcaatg ctagttatga
     6541 ccttggtgca actaagtggg agaccttccg tcatgtcatc ttccctctat ctatgaacgg
     6601 tgtgcgaagt ggggttcagt cggtctttat cccaagtttg agtctcttca tgctgacccg
     6661 tttgattggt gggaaccgcg ttatcacctt ggggacggct attgagcaga attttctaac
     6721 caatgacaac tatggtatgg gttcaaccat cggtgtgatt ctcatcctga ccatgttcat
     6781 caccatgtgg gtgactaagg aaaggagaga acgatgaaaa aatttgccaa cctttatctg
     6841 ggactggtct ttctggtcct ctacctgcct atcttttact tgattggcta tgcctttaat
     6901 gctggtgatg atatgaatag ctttacaggt tttagctgga ctcactttga aaccatgttt
     6961 ggagatggga gactcatgct gattttggct cagacctttt tcttggcctt cctatcagcc
     7021 ttgatagcga ccattatcgg gacttttggt gccatttaca tctaccagtc tcgtaagaaa
     7081 taccaagaag cctttctatc actcaataat atcctcatgg ttgcgcctga cgttatgatt
     7141 ggtgctagct tcttgattct ctttacccaa ctcaagtttt cacttggctt tttgaccgtt
     7201 ctatctagtc acgtggcctt ctccattcct atcgtggtct tgatggtctt gcctcgactc
     7261 aaggaaatga atggcgacat gattcatgcg gcctatgact tgggagctag tcaatttcag
     7321 atgttcaagg aaatcatgct tccttacctg actccgtcta tcattgcagg ttacttcatg
     7381 gccttcacct attcgctgga tgattttgcc gtgaccttct ttgtaacagg aaatggcttt
     7441 tcaaccctat cagtcgagat ttactctcgt gctcgcaagg ggatttcctt agaaatcaat
     7501 gccctgtctg ctctagtctt tctctttagt attatcctag ttgtaggtta ttactttatc
     7561 tctcgtgaga aggaggagca agcatgaaaa aaatctattc atttttagca ggaattgcag
     7621 cgattatcct tgtcttgtgg ggaattgcga ctcatttaga tagtaaaatc aatagtcgag
     7681 atagtcaaaa attggttatc tataactggg gagactatat cgatcctgaa ctcttgactc
     7741 agtttacaga agaaacagga attcaagttc agtacgagac ttttgactcc aacgaagcca
     7801 tgtacactaa gataaagcag ggtggaacga cctacgatat tgccattcca agtgaataca
     7861 tgattaacaa gatgaaggac gaagacctct tggttccgct tgattattca aaaattgaag
     7921 gaatcgaaaa tatcggacca gagtttctca accagtcctt tgacccaggt aataaattct
     7981 ccatccctta cttctgggga accttaggaa ttgtctacaa cgaaaccatg gtagatgaag
     8041 cgcctgagca ttgggatgac ctttggaagc cggagtataa gaattctatc atgctctttg
     8101 atggggcgcg tgaggtgctg ggactaggac tcaattccct cggctacagc ctcaactcca
     8161 aggatctgca gcagttggaa gagacagtgg ataagctcta caaactgact ccaaatatca
     8221 aggctatcgt tgcggacgag atgaagggct atatgattca gaataatgtt gcaatcggcg
     8281 tgaccttctc tggtgaagcc agccaaatgt tagaaaaaaa tgaaaatcta cgttatgtgg
     8341 taccgacaga ggccagcaat ctttggtttg acaatatggt cattcccaaa acagttaaaa
     8401 accaaaactc agcctatgcc tttatcaact ttatgttgaa acctgaaaat gctctccaaa
     8461 atgcggagta tgtcggctat tcaacaccaa acctaccagc gaaggaattg ctcccagagg
     8521 aaacaaagga agataaggcc ttctatcccg atgttgaaac catgaaacac ctagaagttt
     8581 atgagaaatt tgaccataaa tggacaggga aatatagcga cctcttccta cagtttaaaa
     8641 tgtatcggaa gtaggagata aacgtaagaa gacgaatcag tcaagctggt ttgtttttaa
     8701 ggaatagaag tcagttttta gagccctatc tttttctatt ctagttgttt atttgcttat
     8761 ttgcttgcct agtagtatac taagcctata ctcttcaaac cacgtcagcg ttgccttgcc
     8821 gtactcaagt acagcttgag gctagcttcc tagtttgctt tttgattttt attgagtatt
     8881 aaccttacag aaagcggcaa caaataatga aaatgtctac ttttttcaaa aaaagtttct
     8941 ggccaacctt tatgattgtt aaccaaactg ctatactatt ccatttaaag gatggcttgg
     9001 atcgacaata cctaacaact gagtccatat attgggtgat aggcaccttt atatttggaa
     9061 atattctagt agctgtgttt agtaatatga aaatttggga taaaaagaaa aatggcagta
     9121 agaaaaaata tatcctgaaa aagtaatcag agatgtaggg aattggtcta attcaacgga
     9181 gatcatttcc agttgacgca agcttaaaaa aacgttataa taagaaagtt gagaattgat
     9241 tttcacttgt cttagtccag agaaatggcg gtgctgcgag ccatctaagc taggaagtca
     9301 tgctactcaa tcatacaatt gcataagaac aagagaatga caagttcatt gaatgaaggt
     9361 ggtaccgcgg tttttcgccc ttcgtgatat gagcttgtct tttgattttt ggaggtgttg
     9421 atgaaaacat ttcttgtcaa acaaaagttt cgtcttggag gcgaacgctt cgctatcaag
     9481 gatgacaggg gagaaattgc ctatcaggtg gagggatcat tttttaagat tcccaaaact
     9541 tttaccatct atgatgcggc tggtgaacaa gtcagtcaga tcagtaaaga aatcttgacc
     9601 ttgcttcctc gttttgagat tcagcttcgg gatggctcga gttttgtcat tcgtaagaag
     9661 ttgaccttct ggcgagataa gtatgagttt gataatctag gtcttcgtat cgagggcaat
     9721 atctgggatt tgaatttcca attgctggat gatcgcgatc agttgattgc ggaaattaag
     9781 aaggaactct tccatctgac ctctacctat accgtaacgg ttcttgaaga cgcttatgca
     9841 gacctagtca tttccctctg tgtcgcgatt gactatgtgg aaatgctgga aagccaatca
     9901 cattaaacaa gtgaataagg agacaatatg aaacaactat ctagtgcaca agtacgccaa
     9961 atgtggcttg atttctgggc gaccaaaggt cactcagtag aaccatcagt aagtttggtt
    10021 cctgtaaatg acccaactct tttgtggatc aactctgggg tagcaaccct taagaaatac
    10081 tttgacggga ccattatccc tgaaaatcca cgtattacca atgcccaaaa ggctatccgt
    10141 accaacgaca tcgaaaacgt agggaagact gcgcgtcacc ataccatgtt tgaaatgttg
    10201 gggaacttct ctatcgggga ttacttccgt gacgaagcta tcacttgggc ttatgagctt
    10261 ttgacaagcc ctgaatggtt tgatttccct gctgaaaaac tttacatgac ctactatcca
    10321 gacgataaag attcttacaa ccgctggatt gaagtgggag tggatccaag tcacttgatt
    10381 ccaattgagg acaacttctg ggaaatcggt gcgggacctt ctggaccaga tacagaaatc
    10441 ttctttgacc gtggggaagc ctttgaccca gaaaatatcg gtcttcgcct gcttgcagaa
    10501 gatattgaaa acgaccgtta tattgaaatc tggaacatcg ttttgtcaca atttaacgca
    10561 gaccctgctg ttcctcgtag cgaatacaag gaattgccac ataagaacat tgatacgggc
    10621 gctggtttgg agcgtttggt ggctgttatc caaggggcta agaccaactt tgaaacggac
    10681 ctctttatgc cgattatccg tgaagtcgag aaattgtctg gtaaggttta tgaccaagat
    10741 ggcgacaaca tgagcttcaa ggttatcgca gaccacattc gttctctttc atttgctatc
    10801 ggtgatggtg cccttccagg aaatgaaggt cgtggttatg ttcttcgtcg tcttctccgt
    10861 cgtgcttcta tgcatggtca aaaattgggt atcaacgagc ctttccttta caaacttgtg
    10921 ccaactgttg gaaaaatcat ggaaagctac tacccagaag tgcttgagaa acgtgacttt
    10981 attgagaaaa tcgttaagag cgaagaagaa tcatttgccc gtacccttca ctcaggtcaa
    11041 cactttgccc aaggcattgt ggcagacttg aaagaaaaag gtcaatctgt cattgctggt
    11101 caagatgtct ttaaactcta tgatacatac ggattcccag ttgaattgac tgaagaaatt
    11161 gctgaagaag ctggtatgac tgtagaccgt gaaggttttg aagcagccat gaaagaacag
    11221 caagaacgcg cgcgtgcgtc agctgtcaag ggtggctcaa tgggtatgca aaatgaaact
    11281 cttcaaaaca tcactgtaga aagtgtcttc aactacaatg ctagccaatt gtcttctaaa
    11341 ttggtagcta tcgttgctga caatgcagaa gtaggagctg tttcagaagg aactgcctct
    11401 cttatctttg cggaaacgtc attttatgct gaaatgggtg gacaggtagc tgactacgga
    11461 caaatcttgg atgagtcagg taaggttgtg gctactgtga ccaatgttca gaaagcccca
    11521 aatggtcaag cccttcatac agttgaagtc cttgcaccgc ttgccttgaa ccaagaatat
    11581 accttggcaa ttgatagcaa tcgccgtcac cgtgtcatga aaaaccacac tgcgactcat
    11641 ttgcttcacg ctgcccttca caatatcctt ggaaaccacg caacacaggc aggatctctt
    11701 aacgaagttg aattccttcg ctttgacttt acccacttcc aagcagtaac tgctgaggaa
    11761 cttcgtgcga ttgaacagca agttaacgag aaaatttggg aagcacttga agtgaagaca
    11821 gttgaaacgg atattgacac tgctaaagaa atgggagcta tggccctctt tggtgagaaa
    11881 tacggcaagg aagttcgtgt cgtgactatc ggtgactact ctattgaact ttgtggtggt
    11941 actcatgttg gcaacacttc tgagattggt ctcttcaaaa ttgtcaaaga agaaggaatc
    12001 ggttcaggaa ctcgccgtat cttggcagtg actggtaagg aagcctttga agcctatcgt
    12061 gaacaagagg atgctcttaa agctgtcgca gcaaccttga aagcacctca agtcaaggaa
    12121 gtacctcaca aggtagaagg acttcaagaa caacttcgtc aacttcaaaa agaaaatgct
    12181 gagttgaaag aaaaagccgc agctgcagcc gcaggcgata tcttcaaaga tgttaaggaa
    12241 gtcaacggtc atcgttacat tgctagtcaa gtgtctgtat ccgatgccgg tgcccttcgt
    12301 acttttgcag ataactggaa acaaaaagac tactctgatc ttcttgtcct agttgccgct
    12361 atcggtgaca aagtcaatgt ccttgtagca agcaagacaa aagaccttca tgcaggaaac
    12421 cttgtcaaag aattagcacc aatcatcgat ggacgtggtg gtggtaaacc agacatggcc
    12481 atggcaggag gaagcaacca agctaagatc caagaattgt tggatgcagt agcaggtaaa
    12541 ttgtaatcaa gtaaagatct atccatttgg gtaggtcttt ttgtgaatac aaaaaagcca
    12601 aatccgcttg gacctagctt ggttattatg agctattaga tggtattgac tgcccagaca
    12661 cttacggatc tagctgagac agggaattgt ccataacctt cctcatcaat tgtaacttga
    12721 ccttggtggt taccaagtaa atctacaaag gtttgattag tccattcttg accgacaaac
    12781 attgacttgc tgttttcttg gtcatttgag ataaggactg cgattgggga ttgattttca
    12841 gcacctgaac gtacccaacc gatacagtta gcatggtcaa agtagtcatt ttgttctcca
    12901 taggccaagt cttttcggat ggctaggagg cggtcaagga tttctttgaa atcttcttga
    12961 gcatactggc ctgaaatccc atagtagtct ccgtaaaaga cacatggaag gccgtcttgg
    13021 cgtaacaaaa tgagggcata ggctgctggc ttgaaccatt cttcaacggt agactcaagg
    13081 gcttgtcctc gttgggtatc gtggttgtcg acaaaagtca cagccttgtc aggcttgagt
    13141 tcaaccaggc tatctgtgaa aatgccacga aggtcatagt ttgcgccagc ttgactggct
    13201 tcaaagagat tctggtggag acgaacatcg acaaggtcaa agtgttcttc cgttttttcg
    13261 agatagtcca gattggcttc cttgtctggg ttccaaaatt caccaaaaac atagaaatcg
    13321 tcaccgtatt tttccttcat atcgcggatg aaattgcgca taaagaaaga gtcaatatgc
    13381 ttaacggcat ccaaacggaa accagctaca ccagtcgttt ccatgaacca atcagcccag
    13441 tcatagatgt tttggatgac ttcaggatgt ttaaagtcta ggtcggcata catgaggtag
    13501 tcgtagtttc cgttttcgtt atcgaccaat tcctcgttag cccagccctt gttgtctcct
    13561 tggattaggt aaatcccgga tttacggcgt ttggcatcat agtctgtacc tgtgaagtgg
    13621 taccagtgcc agtggaagtc attgtaggta tcttggcgac catcgaaggt aaaactagtc
    13681 cagccattga tggtgaaggg ttctccaagt tcaactgtac ggtctacagg atccacttca
    13741 ataacctgaa aggcttccct gtgatcagca gcagccttgt ggttgagaac tacatcggcc
    13801 ataggttgaa ttccctgcgc tttaagggct tgaatggctt gaagatagtc ttctttgaaa
    13861 ccatacttgg tgcggacagt ccctttttgg ttgaactctc ctaagtcaaa taagtcatag
    13921 accccatagc cgacatcttt ttcgttggtt gccttgaagg ctggtggcat ccagacgtga
    13981 ctgatcccca gatgagctag gtgtggagca ttttcagcca gacgcgtcca gtgttgaccg
    14041 tcgtggggca gataccattc aaagtattgc atgagtgttt gattttgcat gatgtttcct
    14101 cttacttgtc aatcttgttc tttattctat cataaagtat ctctcggagc aaacgtttgc
    14161 gtaagataga aggaaactat tttaactact taaaataaag tattgatttt tttgtatcaa
    14221 agtgctagta tagcgatgta taatacagat aaagatagga gtcatcccat gattgaattt
    14281 caaaatgtta gtaagttgta tggtgataaa gaggccttga gtaatctcaa tttgcagatt
    14341 gaaaatggag agattatggg cttgattggt cataatgggg ctggaaaatc gaccaccata
    14401 aaatccctag tcagtatcat ttcacccagc agtggtcgta ttttggtaga tggtcaggag
    14461 ttatcggaaa atcgcttggc gatcaaacga aagattggct acgtagcaga ctcgcctgac
    14521 ttatttttac gtttaacggc caatgaattt tgggaattga tcgcctcatc ctatgatctg
    14581 actagctctg acttggagac tagtctagct aggctattga acgtttttga ttttgctgaa
    14641 aatcgttatc aggttattga aaccctttct catggaatgc gtcagaaagt ttttgtcatc
    14701 ggggcactct tgtctgatcc tgatatttgg gtcttggacg aacccttgac tggtttggat
    14761 ccccaggctg cctttgattt gaaacagatg atgaaggaac atgcacaaaa agggaagacg
    14821 gtcttgtttt caactcatgt cctagaggta gccgagcaag tctgtaatcg gattgccatt
    14881 ttgaaaaagg ggcatttgat ctattgtggt agtgtagaga acttgaggaa agaccaccca
    14941 gaccagtctt tggaaagtat ctaccttagt cttgctggta gaaaagagga ggttgcggat
    15001 gcgtctcaag gtcattaaaa aattagttga tatcaatatc ctctattcat ctcaagaagc
    15061 taatctggct aatctacgaa agaagcaggc taagaatcct gggaaaaaag taaatgtttc
    15121 cgctagagtc ctaagttctt acattttttc tagtctcttg atgcttttca tgtctataaa
    15181 tatagccttt cgttttcctt ttgaggaaat gccaagtttt tttagtacga tggttgctat
    15241 tttactggtg ctggcctttt caacttcttt cactgcattt tacaatgtct tttatgagag
    15301 taaggacctg gcctcctata ggccctatgc ctttaaagaa tcagagatta taatggccaa
    15361 aggtctgtct gtcctcttgc cagctctaac tggaattgta ccaatcctag cttattttct
    15421 agccctctat attagtctag ctccttctct ttggctgggt ttgcctttga tgctactgtc
    15481 cttgacctta ttatttgtct ctgttacttt agtgacggta gtggcagtac atttcttggc
    15541 tcagactagg gtcttcagaa agtatcagtc tattttttcg aatgtgatga ttgggatagg
    15601 agttctcata cctttaatat ttatcttctt tcttcagtcg acttttggaa gtattgttga
    15661 caaagttaga gacattccat ttcttcttta tcctcttcat atcttttaca aaatagcagt
    15721 ggagcctttt tcgacagaag ccttagtggg tctgctcgct tggataggac taactctctt
    15781 cctgctttat ctgaccaaaa agaaggtcct tcctcgtttt tatgacgtga tcctgcttaa
    15841 tagtgaggag aaggtcaaaa aagaacgtcg cagcaaggag agaatttcaa ccactaaaaa
    15901 gggatttttc cgcatggttt tacgctacca cctcaccctc ttgggacagg gtactggcgt
    15961 ggttacagtg ctttttacaa gtgctttcct tccttatctc atgatgatca gtctgatttc
    16021 caaaatccga gattctcaga tagttccaga cattcatcct ccatactggt tacccttgtt
    16081 ttttgtagga gtgtttatag cagttgtcaa taacaatatc accagcctgc attcaattgc
    16141 cttgtccttg gagagggaaa atgttgattt tctgaagagt ttaccctttg actttgctcg
    16201 ttatgtgaaa gtgaaatttt ggattatctt tgctgttcag tcctttttac caattctgac
    16261 tttgctcggt ctttctctat atctaggctt gtccatcctt tcgatgattt accttcttgt
    16321 agtctggatc attgccagtg tcatcctttc ttgccaccat tactttaagg acgttaaaaa
    16381 tctgtcaacc aattggagta gcattacgga cctggtgaat cgttcaaatg gcatagtcgc
    16441 catagtttta ttgtttattt atagtgcaat cctgatggcc cttgtaattg ggagcatatt
    16501 cttggttcag tctctctccc ctatccttgc catcaacttg ggagtaggag ctcttatcgt
    16561 cttgcttgct cttgctattt ttggctatca ttattacctg tcacgcatat tggcagaaat
    16621 agaaaaaaga tgagatagtt ggttgcttgc ttgataaatt caattcgaca aacgctttta
    16681 tagtttgtta gaatgtagtt gtaaatgatt aagattggta atcaaaaata tagggaggaa
    16741 tgttttgaat aagaaatata atatagttct attattgttg tttatagttt atttattggg
    16801 atatttttca atttcaaaaa cgttaattcc tataatgtgt ctttttcaag tatttttgat
    16861 agaacatata tttagagttc gaaatagaat gatgcaaata ggtgaaatta taattattgt
    16921 tgcttctata atattattta ttgatagtat attgagtttg taacaaaagg cttctctata
    16981 aaatcaaatt ttccagatac ctactgaagc tgatttattt ctttatcttt cttctactac
    17041 ctttgtcact aaatttgaca gacacatatt gctgatacaa cctctctacc tataatctca
    17101 cagttaacct gaggctagtt tcatagtttg ctatttgatt ttcgttgata aaaaaaatgc
    17161 tcctccaaga cggaagagca ttttttattg tgattcttac acatttactt tctagttttg
    17221 caggaagtct agtataccat tttttaaaag aagagtaaaa aagcaagggt agtttctttt
    17281 ttgagaattg tctaaaagtt tgatataatg gtagttatga atagaataag agtcagcaaa
    17341 agggttgaaa agaagcttgc taaggggcta gttttactag aagccagtga tcttgagaat
    17401 gtcaatctta aggatcagga agtagaggtg cagggtcagg aaggaaactt tcttgggact
    17461 gcctaccttt ctcagcaaaa caagggcttg ggctggtttg tcagcaaaga caaggtggcc
    17521 ttcaatcaag ctttctttga aacgttgttt agaaaagcca aagaaaagag aagcgcctac
    17581 tatcaagatg atttaacaac tgcctttcgt ctctttaatc aagagggaga tggctttggg
    17641 ggtctgacag tggaccttta tggcgactac gccgtctttt cttggtataa ctcttatgtt
    17701 tatcagattc gtcagactat atcagaagcc tttagacagg ttttccctga ggttttaggg
    17761 gcttatgaga aaatccgctt taagggtttt gactatgaat ctgcccatgt ttatggtcaa
    17821 gaagcacctg actttttcac tgttttagaa aatggtgtcc tgtatcaagt ctttatgaat
    17881 gatggcttga tgacaggaat tttcctagac cagcatgagg ttcgcggtag tttagttgac
    17941 ggcttggcta tgggtaaatc cttgctcaat atgttttcct acacagcggc tttttcagta
    18001 gctgcggcca tgggaggagc tagccagaca acttctgttg atctagccaa acgttcacga
    18061 gaattgtctc aagcgcattt tcaggcaaat gggctcagca cagacgagca tcgttttata
    18121 gtcatggatg tctttgagta tttcaaatat gccaaacgca aagacttgac ctacgatgtg
    18181 attgtcctag atccgcctag ctttgctcgg aataaaaaac aaactttctc tgtggccaag
    18241 gattatcaca agttgatttc ccagagtctt gagattttaa atccgggagg gattatcatt
    18301 gccagtacca atgctgccaa tgtttcccgc cagaaattta cagaacaaat tgataaaggc
    18361 tttgcaggaa gaagttacca gattttaaac aaatatggtc ttccagcaga ttttgcctat
    18421 aataaaaaag atgaaagtag taattacctc aaggtgatta gtatgaaggt tagtaaatga
    18481 aattaatcgt ttcagtaatg ccaagaagtt tagaggaggc tcaggctctg gatgccacga
    18541 ggtacctgga tgccgacatc attgaatggc gtgccgacta tctgcctaaa gaagcgattt
    18601 tgcaggtagc tccagccatt tttgaaaaat tcgcaggccg tgagttggtt ttcacgctac
    18661 gaactcgctc cgaaggtgga gaaatcgacc tttctccaga agagtatatc catctaatca
    18721 aggaagttgc gcaactctat caaccagact atattgattt tgagtactat agctacaagg
    18781 atgtttttga ggaaatgctg aacttcccaa atcttgtttt gagttaccat aatttccaag
    18841 aaacacctga gaacatgatg gaaatcttgt cagagttgac gatcctaaat ccaaaacttg
    18901 ttaaggttgc ggtgatggct cacacggagc aggatgtctt agacttgatg aactatacac
    18961 gaggctttaa aaccctcaat cctgaacagg aatatgtgac catttctatg ggtaaggtgg
    19021 gcaaggtctc tcgtatcact gcggatgtga ctggttcgag ttggtctttt gccagtctgg
    19081 atgaggttag tgcccctggg cagatttctc tagctagcat gaaaaaaatc agggagattt
    19141 tggatgaagc ttgatggcta tacacgttta gctgcagttg ttgccaatcc tattaagcat
    19201 tctatttctc ccttcatcca caatagagcc tttgaggcga cagctaccaa cgctgcttac
    19261 gtggcttggg agattgaagc gagtgacttg gcagaaacag tggccaatat tcgtcgctac
    19321 cagatgtttg gcatcaatct gtccatgccc tataaggagc aggtgattcc ttatttggat
    19381 gagctgagcg atgaagcgcg cttgattggt gcggttaata cggttgtcaa tgagaatggc
    19441 aatttaattg gatataatac agatggcaag ggatttttta agtgcttgcc ttcttttaca
    19501 atttcaggta aaaagatgac cctgctgggt gcaggtggtg cggctaaatc aatcttggca
    19561 caggctattt tggatggcgt cagtcagatt tcggtctttg ttcgttccgt ttctatggaa
    19621 aaaacaagac cttacctaga caagttacag gatcagacag gttttaaagt ggatttgtgt
    19681 gctttagaat atgtttctga actgcaagca aggattgccg agtcggattt gctagttaat
    19741 gccaccagtg tgggcatgga tggccaatcc tctcctgttc ctgaaaacat agtcttacca
    19801 gaaactcttt tagttgcaga tatcatatac caaccctttg aaacaccgtt tttgaaatgg
    19861 gctagaagtc agggcaatcc agcagtcaat ggtctgggaa tgttgctcta tcaagctgca
    19921 gaagcttttc aactgtggac aggcaaggaa atgccgacag aagagatttg gcagtcttta
    19981 acagaaaaat accaataaag aaagggagac tctcctatga aaatcagaat cgatattcct
    20041 caccatcctt atgatattca gattgaaaaa ggttgtatgg cccaggctgg tcagtggttg
    20101 cgagaactct ggcaaccgca aaaggtagtc attgtgacag ataaccatgt agcctctctc
    20161 tatgcagaga aggtcaagct cagcctagaa gatgctggtt ttcaggtagc tgtttttgat
    20221 ttcttagaag gtgaagaaag aaagaattta actactgttc agaaagtcta tgaatttcta
    20281 gtcaagcaag gtctgactcg tagcgatgga atcgttgctc ttggtggtgg cgttgttggg
    20341 gacctggctg gatttgtagc ctctacctat atgcggggta ttcactttgt tcagattccg
    20401 actagtttga cagctcaggt tgattcttct atcggtggaa agacaggcgt taacacacca
    20461 tttgctaaaa atatggtggg gacctttgcc caaccagatg gggttttgat tgatccactt
    20521 gttcttgaaa ccctcggaaa aagagagttg attgaaggga tgggtgaagt tatcaagtat
    20581 ggcttgattg aggatccaga actgtgggct ctcttgacgg gactgaatgg ttctgttgag
    20641 agtattttgg aacatgcaga gaccttgatt gaacattctt gtcaggtgaa gcgcaagatg
    20701 gtggttgaag atgagttgga caatggtatt cgtctttacc tcaattttgg ccacactatt
    20761 ggccatgcca tcgaagcgac tgccggttat ggcaaggtca tgcatggaga ggctgttgcc
    20821 atgggaatgg tacagatttc caagattgct gaggaaaaag gcctcatgcc agctggcatt
    20881 acccaatcta tcacagagat gtgtcagaaa ttcggcttgc ctgttgacta tgaaaattgg
    20941 gaagttgaca agctttatca ggctttgact catgacaaga aagcgcgtgg caacaccttg
    21001 aaattggtct tggtgccaga gcttggttca gcgaccattc atccagtttc tctggaagag
    21061 atgaaagact acttggtaaa ataaggagag tgtatgagat atttaactgc aggagaatca
    21121 cacggccccc gtctaacagc tattattgag ggaattccag ctggacttcc attgacagct
    21181 gaggatatca atgaggacct tagacgccgt cagggtggct acggtcgtgg tggtcgtatg
    21241 aagattgaga gtgaccaggt tgtctttact tcgggcgttc gccacgggaa gacgacaggg
    21301 gcgcctatta ctatggatgt catcaataag gaccaccaga aatggctgga catcatgtct
    21361 gcggaggaca ttgaagaccg ccttaaaagc aagcggaaaa ttactcatcc tcgcccaggt
    21421 catgccgatt tggttggggg gattaagtac cgttttgatg atttgcgaaa ttctttggag
    21481 cgttcatcag ctcgtgaaac caccatgcgg gtggcagttg gtgcagtagc caaacgcctc
    21541 ttggctgagc tggatgtgga gattgccaac catgtcgtgg tctttggtgg caaggaaatc
    21601 gatgttcctg aaaatctgac agtcgctgaa attaagcaaa gagctgccca gtctgaagtt
    21661 tctattgtta accaagaacg agaacaggaa atcaaggact atattgacca aatcaaacgt
    21721 gatggtgata ccatcggtgg ggttgtggag acagtcgtcg gaggcgttcc agttggtctt
    21781 ggttcctatg tccaatggga tagaaaattg gatgcaagat tggctcaagc tgttgtctct
    21841 atcaatgcct ttaaaggggt ggaatttggt cttggctttg aggctggtta tcgtaaaggc
    21901 agccaagtta tggatgaaat tctctggtct aaagaagacg gttatactcg ccgtaccaat
    21961 aatctaggtg gttttgaagg tggtatgact aatgggcaac ccatcgttgt tcgtggggtc
    22021 atgaaaccca ttcctactct ttataaacct cttatgagtg tggatatcga aacccacgaa
    22081 ccttacaagg caaccgtgga gagaagtgat ccgactgctc ttccagctgc aggaatggtc
    22141 atggaagcag ttgtagcaac ggttctggcg caagaaatcc tcgaaaaatt ctcatcagat
    22201 aatcttgagg aactaaaaga agcggtagcc aaacaccgag actatacaaa gaactattaa
    22261 ggagttccta tggcaaaaac aatctatatc gcaggtcttg ggttgattgg agcctctatg
    22321 gcacttggta tcaaacgcga tcatccagat tatgaaattt taggttataa tcgtagtcaa
    22381 gcttcgagag atatcgcctt gaaagaaggc atgattgacc gtgcaacgga tgattttgct
    22441 agttttgctc ctttggcaga tgtcattatc ctcagcttgc caatcaaaca aactattgct
    22501 ttcattaagg agttggccaa tttggatttg cgagaaggcg ttattatttc agatgctggt
    22561 tcgaccaagt caaccattgt ggatgcggcg gagcagtatt tggctggcaa gtctgttcgc
    22621 tttgtcgggg cccatcccat ggctggtagt cacaagacag gggctgcttc ggcagatgtc
    22681 aatctttttg aaaatgccta ttatatcttt acaccttcaa gcctgacaag tcaggacacg
    22741 cttaaggaaa tgaaggatct actttcaggt cttcatgctc gttttatcga gattgatgcc
    22801 aaggagcatg atcgtgtcac ttctcagatt agccattttc ctcatatttt ggcttctagt
    22861 ctcatggagc agactgcggt ctatgctcaa gagcatgaga tggcaaggcg ctttgcggca
    22921 ggtggttttc gagatatgac ccgaattgcg gaaagcgagc caggaatgtg gacctccatt
    22981 ctcttgtcca atagcgagac cattctggat agaattgagg atttcaagga acgtttggaa
    23041 gtgattggtc aggccattag taagggagat gaagagcaaa tttggaactt ttttaaccaa
    23101 gcgcgtgaac aacgccagac catggaaatc cataagcgtg gtggtgtgga tagctcttac
    23161 gacctctatg ttgacgttcc tgatgaagaa gatgtcatcc tgcggatttt ggaactgcta
    23221 cgtggaactt ccttggttaa catccacatc aacgaggaaa atcgtgagga tattcacgga
    23281 atcctacaaa tttcatttaa aaatgctcaa gacttggaaa gagctgagca tctcataaca
    23341 gaaaataccg actatacagt cgtcatcaaa taaggagaag aacatgtcaa atatttacga
    23401 tagtgcaaac gaactcagtc gcggtctacg cggattacca gaatacaaga ctgttaaagc
    23461 agctaaagat gcgattgcag cagatgctga ggcaagcaaa atctttacag aatatcttgc
    23521 ctttcaagag gaaattcaaa aactagcaca gacaggtcaa atgccagatg cgtccttcca
    23581 agctaagatg gaaggctttg gtaaacagat tcaaggaaat agcctcttgt cagaattctt
    23641 taccaagcaa caacaattgg ccatttacct ttctgacatt gaaaaaattg tttttgaacc
    23701 agtttcagaa ttgctgaaat aagaaaagaa cgatcctaaa gtcaggaatt tttaaggaat
    23761 ttctggcttt ttatgataaa ataggtaaaa gtattgcaag tatgaggtcc agtatgaaac
    23821 taaaaacaaa cattcgccat ttacatggta gtatccgcgt cccaggtgac aagtctatca
    23881 gccaccgttc cattatcttt ggaagtttgg ctgagggtga gaccaaggtt tatgatattc
    23941 tgcgaggtga agacgtcctt tcgaccatgc aggtttttcg tgaccttggt gttgaaattg
    24001 aggataaaga tggggttatt accattcaag gtgtaggcat ggctggctta aaagcgccac
    24061 aaaatgccct taatatggga aattctggca cctcgattcg cctgatttca ggtgtccttg
    24121 ctggtgcaga tttcgaagta gagatgtttg gagatgatag tctttccaaa cgtcctatgg
    24181 accgtgtgac ccttccactg aaaaaaatgg gcgtcagcat ttcaggacaa actgaacgag
    24241 acttgcctcc ccttcgctta aaagggacga aaaacctaag acctattcat tatgagttgc
    24301 caattgcctc tgcccaagtc aagtcagcct tgatgtttgc agccttacaa gctaaggggg
    24361 agtcagttat tatcgaaaaa gagtgcactc gtaatcatac tgaagatatg ttgaaacaat
    24421 ttggtggtca tttaagtgtg gacggtaaga aaatcatagt ccaagggcca caaaaattga
    24481 caggacagaa ggtggtcgta ccaggagata tttccagtgc agccttttgg ttagtcgcag
    24541 gtttgattgt tccaaattct cgtctagtgc tgcagaatgt ggggatcaac gaaactcgca
    24601 ccggtattat tgatgtcatt cgtgccatgg gtggaaaatt ggaaataact gaaatcgatc
    24661 cagtcgctaa atctgcaacc ttgattgttg agtcttctga cttgaaagga acagagattt
    24721 gtggcgcttt gattccacgt ttgattgatg aattgcctat tattgcccta cttgcgaccc
    24781 aagcccaagg tgtaacagtt atcaaggatg ctgaggagct caaggtcaag gaaacagacc
    24841 gtattcaggt tgtggcagac gccttaaata gtatgggagc agatattact cctacggcag
    24901 atgggatgat tatcaaagga aaatcagctc ttcacggtgc tagagtcaat acgtttggtg
    24961 accaccgtat cggcatgatg acagctatcg cagccctctt ggttgcagat ggagaggtgg
    25021 agcttgaccg tgcagaagcc atcaatacca gctatcctag tttctttgat gatttggaga
    25081 gcttgattca tggctaaggt gttattaggg tttatggggg ctggaaaatc gactattgca
    25141 agaggcttgg acactaatta ccttgatatg gatgctctga ttgagaagcg cctaggtatg
    25201 tccattgcga attttttcgc tgaaaaggga gaagcagcct ttcgtcatgt agaatcagaa
    25261 gtcctagctg atttactaca aacagaccaa gtcgtgtcaa ctggaggagg agtggttatt
    25321 tctcagagaa atcgtgactt actcaagact aatacagata acatctacct gaaagcagat
    25381 tttgaaaccc tctacctacg tatcgcagct gataaggaca atcagcgacc gctttttcta
    25441 aataatagca aggaagaact agtagctatt tttcaagaaa gacaggcttg gtatgaggaa
    25501 gtggctagtc gggttttgga tgtgaccaag ctaagcccag aggaaattat agaggaacta
    25561 agatgaaaat tgcttatcta ggtcccaagg gatcattttc acaccacgtt gtgcagacag
    25621 cttttcctca tgaggaattg caggcttttg acaacattac agatgtcatc aaggcttatg
    25681 agcaaggatt agtggactat tctgtggtgc cagttgaaaa ctctattgag ggtagtgttc
    25741 atgaaacctt ggactatctt tttcatcagg ctcacatcca agcagtagca gaaatcgttc
    25801 agcctattca tcagcagttg atggtggttc caggccatac taagattgaa aagatttttt
    25861 cacatccaca ggccttggct caaggaaaga aattcatcga tgaacaatat ccagaggctc
    25921 aaatcgaggt aacagctagt acagcttatg cggcccgttt tatttccgaa catccagatc
    25981 agccctttgc agcaattgca cctagaagtt ctgctgaaga atatggattg gaactgattg
    26041 ccgaggatat tcaggaaatg gaagccaatt tcacacgttt ctgggttcta ggagctgaaa
    26101 agcctagtat tcccttgcaa gcacaaactg aaaagatgag tttggccttg acattacctg
    26161 acaaccttcc aggtgcactt tataaggccc tgtcgacctt tgcttggcga ggaattgact
    26221 tgacaaaaat tgaaagtcgt ccactcaaga cagcactggg tgaatacttt ttcattatcg
    26281 atgtggatta taccgataag gacttggtcc actttgccca aaaagaatta gaagcgattg
    26341 gaatccagta taaaattctg ggtgcctatc ctatttatcc aatatcagac catggaaagg
    26401 agagaagatg agtaaagaaa atcccttaag tcatcatgag cagttgcgtt atgattattt
    26461 gctaaaaaat attcactatc tcaatgagag agaaaaaaat gagtttgcct atttgcaaga
    26521 aaagctaact cttgctaggg gaaatagtag ctctagcttg gaacaagaaa gagaagagca
    26581 ggttgactta ccaagctatg cgaaccggag tcgctcacaa tccaaatcac aagcactctc
    26641 tttccctcca aaaaagaaaa gacggaagct ccgtcttaaa cgaattttta tggtgatttt
    26701 ttcacttttg gtctgtgtgg ctttggccat ggtattcatg tttttgcgtg gttaccaaga
    26761 tgctagcgca aagaaaactg ctgatgcccg ggcagctcaa gtagaagtct ttaatggtca
    26821 ggacactaga gatggagtta atattttaat catgggtact gatggtcgaa tcggccagaa
    26881 cagtgttgag acacgaactg actctattat ggtattaaat gtcgggggct cagataagaa
    26941 aatgaagcta gtcagtttca tgcgtgataa tttggtctat atagatggtt atagtcaagt
    27001 gattaacggt agaaaacaga cagataacaa gttaaacgta gcctacgagt taggagaaca
    27061 agaggggcaa aaaggggcag aaatggttcg ccaagtcttg aaagataatt ttgacttgga
    27121 cattaagtac tatgccttgg ttgatttcca agcctttgcc acagcgattg acacgctttt
    27181 ccctgatggg gtgacgattg atgctcaatt ttcaacattg aatgggcgtc ccctaacaga
    27241 agctacagtc ggagatgatt tatacgctac cgagactgag tctccaaccc aaaccattaa
    27301 agtcggaaaa cagcagatga atggctcgac cctgctcaat tatgctcgtt tccgtgatga
    27361 tgatgaggcg gattacggcc gtacaaaaag acagcaacaa gttttaacag caattttaga
    27421 gcaaattaaa gatcccacta aacttttcac tggttctgaa gctcttggaa aggtttttgc
    27481 tatgacctca accaacgtac cctatacttt cctcctaaca aacggtttat ctgttttgga
    27541 tggagcaaaa aatggtattg aaaaattgac gattccagaa ctgggtgact gggtagatgc
    27601 ctatgatgtt tatggaggct tgggcttgct ggttgatcaa aacaaatatc aaaccaagct
    27661 cgctcaaatg ggcttgagat aagataatac tcaatgaaaa tcaaagtgca aactaggaag
    27721 ctagccgcag gctgctaaaa acacagtttt gaggttgtag ataagactga cgaagtcagt
    27781 tacctatacc tacggcaagg tgaagctgac gtggtttgaa gagattttcg aagagtataa
    27841 gacagaaaaa tcaaagtttg atagctattt ggatagcagt caggctttga ttttttacag
    27901 tctgcaatag attttcaccc cttgtttgtg gtataatgaa acgatacgat agaaagaata
    27961 atgaacaata tgactgattt aaaagcaatt caggctcgta gtctggagat ggctgaatat
    28021 tttgtggcct tttgtaaaga acatgatttg ctctgttatc tctgtggcgg aggcgctatt
    28081 ggtacccttc gaaacaaggg atttattcct tgggacgacg acctagactt ttttatgcct
    28141 cgtaaagatt atgagaaatt agcagaatta tggcctcgtt atgcagatga acgttatttc
    28201 ttgtcaaaga gtcacaagga ttttgttgat cgtaatcttt ttattaccat tcgtgacaag
    28261 aaaaccacct gtatcaagcc ttatcagcag gatttggatt tgccacatgg tctggccttg
    28321 gatgttttgc ctttggatta ttatccgaaa aatccagctg agcggaaaaa acaggttcgt
    28381 tgggccttga tttattcact cttttgtgcg caaactattc cagaaaagca tggtgctctc
    28441 atgaaatggg gaagtcgcat tttactgggt ttgactccaa aatctctccg ttatcgcatc
    28501 tggaaaaaag ctgagaaaga aatgactaag tatgatttgg ctgattgtga tggcattaca
    28561 gaattatgct caggtcctgg ctacatgaga aacaagtacc caatcacatc ttttgaagac
    28621 aatcttttct tgccatttga aggaacagag atgcctattc caatcggcta tgatgtctat
    28681 ctcagaactg cttttgggga ttatatgacg cctccaccag cagacaagca ggtaccgcat
    28741 catgatactg tcattgctga tatggataag tcttatacag aatacaaggg agaatatggt
    28801 ggctaagaaa aaaatcttat tttttatgtg gtctttttct cttggaggtg gtgcagagaa
    28861 gattctatca accattgttt caaatctgga tccagaaaag tatgatattg atattcttga
    28921 aatggagcac tttgacaagg gatatgaatc tgttccaaag catgtacgca ttttaaaatc
    28981 ccttcaagat tatcgccaaa ccagatggtt acgagctttt ttgtggagaa tgagaattta
    29041 ttttccaaga ctggctcgtc gtttgcttgt aaaggatgat tatgatgttg aagtttcttt
    29101 taccattatg aatccaccac tgttgttctc taaaagaaga gaagtcaaga agatatcttg
    29161 gattcatgga agtattgaag aacttcttaa ggatagctct aaaagagaat cacatagaag
    29221 ccagttggat gctgcgaata caattgtagg gatttcaaaa aagaccagca attctatcaa
    29281 ggaagtttat ccagattata cttctaaatt acagacaatc tacaatggat atgattttca
    29341 gactattcta gaaaaatctc aagagaagat cgatatcgag attgctcctc aaagtatctg
    29401 tactatcgga cggattgagg aaaataaggg ttctgaccgt gtagtggaag tgatacgatt
    29461 attacaccaa gagggaaaaa actatcatct ctattttatc ggggctggtg atatggaaga
    29521 ggaactgaaa aaacgagtca aagagtatgg gattgaggac tatgtacatt tccttggtta
    29581 tcaaaaaaat ccttatcagt atctatctca gacgaaagtt cttttgtcta tgtctaaaca
    29641 agaaggtttt cctggagtgt atgtggaggc cttgagtctg ggactccctt ttatctctac
    29701 ggacgttgga ggggctgagg aattatccca agaaggacga tttggacaaa tcattgagag
    29761 caatcaagag gcagctcagg cgattactaa ttacatgact tctgcctcaa actttgatgt
    29821 cgatgaggct agccaattca ttcaacaatt tacaattaca aaacaaatcg aacaagtaga
    29881 aaaactatta gaggagtagc atggaaactg cattaattag tgtgattgtg ccagtctata
    29941 atgtggcgca gtacctagaa aaatcgatag cttccattca gaagcagacc tatcaaaatc
    30001 tggaaattat tcttgttgat gatggtgcaa cagatgaaag tggtcgcttg tgtgattcaa
    30061 tcgctgaaca agatgacagg gtgtcagtgc ttcataaaaa gaacgaagga ttgtcgcaag
    30121 cacgaaatga tgggatgaag caggctcacg gggattatct gatttttatt gactcagatg
    30181 attatatcca tccagaaatg attcagagct tatatgagca attagttcaa gaagatgcgg
    30241 atgtttcgag ctgtggtgtc atgaatgtct atgctaatga tgaaagccca cagtcagcca
    30301 atcaggatga ctattttgtc tgtgattctc aaacatttct aaaggaatac ctcataggtg
    30361 aaaaaatacc tgggacgatt tgcaataagc taatcaagag acagattgca actgccctat
    30421 cctttcctaa ggggttgatt tacgaagatg cctattacca ttttgattta atcaagttgg
    30481 ccaagaagta tgtggttaat actaaaccct attattacta tttccataga ggggatagta
    30541 ttacgaccaa accctatgca gagaaggatt tagcctatat tgatatctac caaaagtttt
    30601 ataatgaagt tgtgaaaaac tatcctgact tgaaagaggt cgcttttttc agattggcct
    30661 atgcccactt ctttattctg gataagatgt tgctagatga tcagtataaa cagtttgaag
    30721 cctattctca gattcatcgt tttttaaaag gccatgcctt tgctatttct aggaatccaa
    30781 ttttccgtaa ggggagaaga attagtgctt tggccctatt cataaatatt tccttatacc
    30841 gattcttatt actgaaaaat attgaaaaat ctaaaaaatt acattagaac gggggtgacc
    30901 aagtgattga tgggaaacga ttattattta gtttgaccat agtcagttat gccttgacgc
    30961 tagtaagtgg aattgtgtat ctgtttaata ataataatgt tagcttactt tctactttat
    31021 tgttcttgtg ggttagtagc ttaattgctt gttggaatga tatcaagtat tacttaatcc
    31081 attttatttt ctatttaacc atttttgtat ttctggtatc aagaccgacc attgattatt
    31141 ttagggatgg tgctttggat acctatcatc caatagccta tcgttttgcc tttatagttg
    31201 tcatggtttc gattctgggc ttgaccacag gaggcattct ggctcgttac ttcatagcta
    31261 ggaagaaaat aaaagtagca aatataggaa attctctaaa agaggtttat atcaagcggt
    31321 tacgctttgt atcactagga gtttttcttc taacctatcc tttctatttc attcggttat
    31381 ttgaacggct cttgtatcgt ttgcagactt cctactatgc ctactatgca aattttgaaa
    31441 gtaaactgcc ttattttacc tacattttgt ctacctttac ggtctatgca atgtgtatgt
    31501 atctagcaac caagccaaag aaattgcagg ccacagcagt gcttgtctcc tttattgcag
    31561 ctaatactat tcatttggca attgggacac gaaatccctt tattttaagt attttatttg
    31621 cttttgttta ttactttatg cgggagcaag ctgaaaaagg aaaatggatt gggtttaaag
    31681 aaaagttagc gatttttgta ggttctccta ttctcatgtt agcgatggga gtactcaatt
    31741 atgtacggga taatgtccaa gtttctcata caggtttctg ggatatctta cttgacttta
    31801 tctataaaca agggactagt tttggtgttc tggctcgagg ttttctattt aacagtagcc
    31861 tcccttaccg agatttccgt aattttactt ttggtcctgt tcttgattat tttgcaaggg
    31921 ggagtttggg agccattttc ggaggaaaag cctttgaaca tacaaccaat agtgtggaac
    31981 tagctattga tagtaatagt tatgcccaca atctatccta tcttgtcttg aacaaggaat
    32041 acttgaaagg gcatggtatc ggaagtagtt atatcatgga gttgtatacc gactatggta
    32101 tgattggagt ctttctgctt agtttcttac tcggcgtatt atttatagcc atgctgcaag
    32161 tagcctatcg ctcaaggaca atcctatttg ctttatccct actcatcttg aataatctat
    32221 tctttatgcc aagaagcagc ttttcagaaa gtttcttcaa tttatttaca atgcaattct
    32281 ggggaattgt tcttgtgatt atatttgtag caaaaatgct tacaaaggaa aactagtatc
    32341 tactaaacaa aggagaaaaa aatcatgttt gaacattatt cagtagctga tttgtttgca
    32401 aatctttata aaaaacgaaa agcaaatatt ttagctctca tcgctttatt tgctctcatt
    32461 gctgtaccat ttacaattaa agcagttagg aataaaaaca ctgtcaaaga tacaacaagt
    32521 tattcaactt atcttatcta taaaatcact cctccagaag attcggccaa aacgattttg
    32581 aatcatcaaa ttggtggtta tagtgatttt tatgggaaat tgattgatgg taatttgaat
    32641 ggagcttatc ttttcaatga tgtagaaccc agtgagttga aaaaaattgc cagtgaatta
    32701 gacacgacgg aaacaacctt gaaaaattca acgaatgact attggtggaa aaaattgacc
    32761 gtctactata tgattgacga tgcaggggtt ggtgtgaaaa ttttgacatc aagtaaagat
    32821 gccaatgact tgttagagaa aaaaattgat gggttgattg agaaatttaa acatgcttat
    32881 gcaaatgtga aaattgaaaa actggaaacc atcaactcta aagaattgaa cgcaaatggt
    32941 gaaacagcgc ttggcttaaa tgtgaaaaat ctgattcttc gtttagttgt tattggagtg
    33001 gtttgtgtga ttttggttgt gatgggaaat gtgttagttt atctctttaa tccaacaatc
    33061 aatagagtag gtgatttttc tcagtatcaa attgattttg taacagagat tacaacaatt
    33121 gctaacctag cagatgtttt gtcatacaaa aatactggac aggaattgac catcgttagc
    33181 tcaaataaag ctatcctaga taaattgaaa cagagtcaag aagctttaaa aggaatgcat
    33241 tttgtagatt tgcaggatgt atcatctctt ttggaaagag atacagtcct tcttgttgaa
    33301 gagtacggag tgactcgtta taagaaattt gagcaaagtc ttcaaattct cagaaactta
    33361 aatcgttcta tcctcggtgt agcaaccttt aaattataag tattctgatg tataaggtct
    33421 tcaaaatcgg ctcttagccg attttgaagg ctttttctat ctgtctgcag aaattttctc
    33481 ttggagtctc ctatagaaag accctaggga aaatctatcc gtatagagga gccttctttt
    33541 gataaaatcg taaaaatcta gtataataga tagaactgaa agtatgaggt tactagcaat
    33601 gaaaatgaaa caaattagtg atacaacttt aaaaatcacg atgtctttag aggatttgat
    33661 ggatcgtgga atggagattg ctgactttct cgttcctcaa gaaaaaacag aagagttctt
    33721 ttatgctatc ttggatgagc tagagatgcc tgatagcttt ctggatacag gcatgttgag
    33781 cttccgtgtg actccaaaac ctgataaggt agatgtcttt gtgaccaagt caaagattga
    33841 ccaaaatcta gattttgaag acttatcgga tttgccagat atggaagaat tggctcaaat
    33901 gtctccagat gaatttatca aaaccctgga aaaaagcatc gcagacaaaa ccaaggatga
    33961 tatcgaagcc attcaatctc ttgagcaagt tgaagccaag gaagaagagc aagagcaggc
    34021 tgaacaagaa gctgagagta agaaagaacc ttacatctac tacatccttt cttttgctaa
    34081 gttggctgac ttggtagctt ttgccaagac agtgactttt gaaatggaaa cttctgaact
    34141 ctacaaaatg aacgagcgct attatttgac cattttagtg gatattgaaa atcatccaag
    34201 cccatatcca gcttggctgt tggcccgtat gcgcgagttt gcagacgata gtgatattag
    34261 tcgctcagtc ttacaagagt atggtcaagt cttgatgagt cacgatgcag tgctcaatct
    34321 gcaaaaaatc ggctaatcct ttctggaaag ctattttcag attttaagaa gagcgaatcg
    34381 tctgattcgt tttttctttt tatactgaaa tagtgattta ctataatagg aattttcaca
    34441 aaattctgtt ataatggcta tattagaaaa tttcgaggag ataaagatga cagttaaaat
    34501 tgctttacta ggatttggta ccgttgcaag tggtgtgcct ttcctcctaa aggaaaatgg
    34561 aggaaaaatc aatcaatcag cacattcaga tatcaaagtt gctaaggtat tggtcaagga
    34621 tgaagatgaa aaaaatcgct tgcttgcagc agggaatgac tttaactttg taaccaatgt
    34681 ggatgatatt ttatcagacc aggatattac tatcgtagtg gaattgatgg ggcgtattga
    34741 gcctgctaaa acctttatca ctcgtgcctt ggaagctgga aaacacgttg ttactgctaa
    34801 caaggacctt ttagctgtcc atggcgcaga attgctagaa atcgctcaag ctaacaaggt
    34861 agcactttac tacgaagcag cagttgctgg tgggattcca attcttcgta ctttagcaaa
    34921 ttccttggct tctgataaaa ttacgcgcgt gcttggagta gtcaacggaa cttccaactt
    34981 catggtgacc aagatggtgg aagaaggctg gtcttacgat gatgctcttg cggaagcaca
    35041 acgtctagga tttgcagaaa gcgatccgac gaatgacgta gatgggattg atgcagccta
    35101 caagatggtt attttgagcc aatttgcctt tggcatgaag attgcctttg atgatgtagc
    35161 ccacaaggga atccgcaata tcacaccaga agacgtagct gtagctcaag agcttggtta
    35221 cgtagtgaaa ttggttggtt ctattgagga aacttcttca ggtattgctg cagaagtgac
    35281 tccaaccttc ctacctaaag cgcacccact tgctagtgtg aatggcgtaa tgaacgctgt
    35341 ctttgtagaa tctatcggta ttggtgagtc tatgtactac ggaccaggtg cgggtcaaaa
    35401 accaactgca acaagtgttg tagctgatat tgtccgtatc gttcgtcgtt tgaatgatgg
    35461 tagcattggc aaagacttca acgaatatag ccgtgacttg gtcttggcaa atcctgaaga
    35521 tgtcaaagca aactactatt tctcaatctt ggctctagac tcaaaaggtc aggtcttgaa
    35581 gttggctgaa atcttcaatg ctcaagatat ttcctttaag caaatccttc aagatggcaa
    35641 agagggtgac aaggcgcgtg tcgttatcat cacacacaag attaataaag cccagcttga
    35701 aaatgtctca gctgaattga agaaggtttc agaattcgac ctcttgaata ccttcaaggt
    35761 gctaggagaa taagatgaag attattgtac ctgcaaccag tgccaatatc gggccaggtt
    35821 ttgactcggt cggtgtagct gtaaccaagt atcttcaaat tgaggtctgc gaagaacgag
    35881 atgagtggct gattgaacac cagattggca aatggattcc acatgacgag cgtaatctct
    35941 tgcttaaaat cgctttgcaa attgtaccag acttgcaacc aagacgcttg aaaatgacca
    36001 gtgatgtccc tttggcgcgc ggtttgggtt cttccagctc ggttatcgtt gctgggattg
    36061 aactagccaa ccaactgggt caactcaact tatcagacca tgaaaaattg cagttagcga
    36121 ccaagattga agggcatcct gacaatgtgg ctccagccat ttatggtaat ctcgttattg
    36181 caagttctgt tgaagggcaa gtctctgcta tcgtagcaga ctttccagag tgtgattttc
    36241 tagcttacat tccaaactat gaattacgta ctcgcgacag ccgtagtgtc ttgcctaaaa
    36301 aattgtctta taaggaagct gttgctgcaa gttctatcgc caatgtagcg gttgctgcct
    36361 tgttggcagg agacatggtg accgctgggc aagcaatcga gggagacctc ttccatgagc
    36421 gctatcgtca ggacttggta agagaatttg cgatgattaa gcaagtgacc aaagaaaatg
    36481 gggcctatgc aacctacctt tctggtgctg ggccgacagt tatggttctg gcttctcatg
    36541 acaagatgcc aacaattaag gcagaattgg aaaagcaacc tttcaaagga aaactgcatg
    36601 acttgagagt tgatacccaa ggtgtccgtg tagaagcaaa ataaagaata gaagatagga
    36661 tggggaaact cttgaccaga gggtttcata tcctttttgt gaaaagaagt ttatactcaa
    36721 tgaaaatcaa agagcaaact aggaagctag ccgcaggctg ctcaaaacag tgttttgagg
    36781 ttgtggatag aactgacgaa gtcagctcaa gacactgttt tgaggttgca gatagaactg
    36841 acgaagtcag taacatacct acggtaaggt gacgctgacg tggtttgaag agattttcga
    36901 agagtattag ttaaaaacgt gataaaggag aaataaaaat ggcagaaatt tatctagcag
    36961 gtggttgttt ttggggccta gaggcatatt tttcacgcat ttctggagtg ctagaaacca
    37021 gtgttggcta cgctaatggt caagtcgaaa cgaccaatta ccagttgctc aaggaaacag
    37081 accatgcaga aacggtccaa gtgatttacg atgagaagga agtgtcactc agagagattt
    37141 tactttatta tttccgagtt atcgatcctc tatctatcaa tcaacaaggg aatgaccgtg
    37201 gtcgccaata tcgaactggg atttattatc aggatgaagc agatttgcca gctatctaca
    37261 cagtggtgca ggagcaggaa cgcatgctgg gtcgaaagat tgcagtagaa gtggagcaat
    37321 tacgccacta cattctggct gaagactacc accaagatta tctcaggaag aatccttcag
    37381 gttactgtca tatcgatgtg accgatgctg ataagccatt gattgatgca gcaaactatg
    37441 aaaagcctag tcaagaggtg ttgaaggcca gtctatctga agagtcttat cgtgtcacac
    37501 aagaagctgc tacagaggct ccatttacca atgcctatga ccaaaccttt gaagagggga
    37561 tttatgtaga tattacgaca ggtgagccac tcttttttgc caaggataag tttgcttcag
    37621 gttgtggttg gccaagtttt agccgtccga tttccaaaga gttgattcat tattacaagg
    37681 atctgagcca tggaatggag cgaattgaag ttcgttctcg ttcaggcagt gctcacttgg
    37741 gtcatgtttt cacagatgga ccgcgggagt taggcggcct ccgttactgt atcaattctg
    37801 cttctttacg ctttgtggcc aaggatgaga tggaaaaagc aggatatggc tatctattgc
    37861 cttacttaaa caaataaaac agagagtggg gcttcccact ttcttcattt ctagaatatg
    37921 aatagaaggg atttatgaaa cacctattat cttacttcaa accctacatc aaggaatcaa
    37981 ttttagcccc cttgttcaag ctgttagaag ctgtttttga gctcttggtt cccatggtga
    38041 ttgctgggat tgttgaccaa tctttacctc agggagatca aggtcatctc tggatgcaga
    38101 ttggcctgct ccttatcttt gcagtaattg gcgttttagt ggccttgata gctcaatttt
    38161 actcagcaaa ggcagcagta ggttttgcta aggaattgac aaacgatctt tatcgtcata
    38221 ttctttcctt gccaaaggac agcagagacc gtctgacaac ttctagtttg gttactcgct
    38281 tgacttcgga tacctaccag attcagactg gtatcaatca attcctgcgt ctctttttac
    38341 gagcgcccat tatcgttttt ggtgccattt ttatggctta tcgaatctca gctgagttga
    38401 ctttctggtt cttagtcatg gttgccattt tgaccattgt cattgtaggg ttatctcgat
    38461 tggtcaatcc tctctacagt agtctcagaa agaaaacgga ccaactggtt caggaaacgc
    38521 gccagcaatt gcaagggatg cgggttattc gtgcttttgg tcaagaaaaa cgagagttac
    38581 agatttttca aacccttaac caagtttatg ctagattaca agaaaagaca ggtttcttgt
    38641 ctagtttatt aacacctctg acctatctga ttgtcaatgg aactcttctc gttattatct
    38701 ggcaaggcta tatttcaatt caaggaggag tactcagtca aggtgctctc attgctctta
    38761 tcaattacct cttacagatt ttggtggaat tggtcaagct agccatgctg atcaattccc
    38821 tcaaccagtc ctatatctca gccaagagaa tcgaggaggt ctttgcggaa tctcccgaaa
    38881 acatccattc agaattagaa caaaagcaag ttaccagtgg tcgggtttta caagtccaag
    38941 aattgacttt tacctatcct gatgcggccc agccttctct gagagacatt tcctttgata
    39001 tgactcaagg acaaatcctt ggtatcattg gggggactgg ttctggtaaa tcaagcttgg
    39061 tgcaactctt acttggactt tatccagtag acaaggggaa cattgacctt tatcaaaatg
    39121 gacgtagtcc tcttaatttg gagcagtggc ggtcttggat tgcctatgta cctcaaaagg
    39181 tcgaactctt taagggaact attcgttcca acttgacttt aggtttaaat caagaagtga
    39241 ctgatcaaga actctggcaa gccttggaga ttgcgcaagc taaggatttt gtcagtgata
    39301 aggaaggact cttggatgct ctagttgaag caggagggcg aaatttctca ggtggacaaa
    39361 aacaaaggct gtctatcgca cgagcagtct tgcgccaggc tccgtttctc atcctagatg
    39421 atgcgacctc ggcactggat accattaccg agtccaagct cttgaaagct atccgcgaag
    39481 atctgccaaa tatgagctta atcttgattt ctcaacggac ttcgacactc cagatggcgg
    39541 accagattct cctcttggaa aaaggtgagt tgctagctgt tggcaagcac gatgacttga
    39601 tgaaatccag ccaagtctat cgtgaaatca atgcatccca acatggaaag gaggactaga
    39661 atgaaacgac aaactgtaaa ccagacgctc aaacgtttag ccgtagattt agcaagccat
    39721 cctttcttcc ttttcctagc ctttctagga actattgccc aagttggctt atcaatttac
    39781 ctacctattc tgattgggca ggtcattgac caagtcctag tggctggttc atcaccagtt
    39841 ttttggcaga tttttctcca gatgctcttg gtggtaatag gaaatactct ggtacaatgg
    39901 gccaatcctc tcctctataa tcgtctaatc ttctcttata ccagagattt acgggagcga
    39961 atcatccata agctccatcg tttaccgatt gcctttgtag ataggcaagg tagtggagag
    40021 atggttagtc gtgtaaccac ggacatcgaa cagttggcag ctggcttgac catgattttt
    40081 aaccaatttt tcattggtgt tttgatgatt ttggttagta ttctagccat gctccaaatt
    40141 catctcctca tgactctctt agtcttgctg ttgacgccac tgtccatggt gatttcacgc
    40201 tttattgcca agagatccta tcatctcttc cagaagcaaa cagagacgag gggaattcag
    40261 actcagttga ttgaagaatc gcttagccag cagactataa tccagtcctt caatgctcaa
    40321 acagaattta tccaaagatt gcgtgaggct catgacaact actcaggcta ttctcagtca
    40381 gccatctttt attcttcaac ggtcaatcct tcgactcgct ttgtaaatgc actcatttat
    40441 gcccttttag ctggagtagg agcttatcgt atcatgatgg gttcaacctt gaccgtcggt
    40501 cgtttagtga cttttttgaa ctatgttcag caatacacca agccctttaa cgatatttct
    40561 tcagtgctag ctgagttgca aagtgctctg gcttgcgtag agcgtatcta tggagtctta
    40621 gatagccctg aagtggctga aacaggtaag gaagtcttga ccagtgacca agttaaggga
    40681 gctatttcct ttaaacatgt ctcttttggc taccatcctg aaaaaatttt gattaaggag
    40741 ttgtctatcg atattccagc tggtagtaag gtagccatcg ttggtccgac aggtgctgga
    40801 aaatcaactc ttatcaatct ccttatgcgt ttttatccca ttagctcggg agatatcttg
    40861 ctggatgggc aatccattta tgattataca cgagtatcat tgagacagca gtttggtatg
    40921 gtgcttcaag aaacctggct cacacaaggg accattcatg ataatattgc ctttggcaat
    40981 cctgaagcca gtcgagagca agtaattgct gctgccaaag cagctaatgc agactttttc
    41041 atccaacagt tgccacaggg atacgatacc aagttggaaa atgctggaga atctctctct
    41101 gtcggccaag ctcagctctt gaccatagcc cgagtctttc tggctattcc aaagattctt
    41161 atcttagacg aggcaacttc ttccattgat acacggacag aagtgctggt acaggatgcc
    41221 tttgcaaaac tcatgaaggg ccgcacaagc ttcatcattg ctcaccgttt gtcaaccatt
    41281 caggatgcgg atttaattct tgtcttagta gatggtgata ttgttgaata tggtaaccat
    41341 caagaactca tggatagaaa gggtaagtat taccaaatgc aaaaagctgc ggcttttagt
    41401 tctgaataag ccattctctt ttgaaagttt atggacgaaa aaagttgcct tcgagtgact
    41461 tttttgttac aatagctaga aaaattgttc actgtaatac tcaatgaaaa tcaaagagca
    41521 aactaggaag ctagccgtag gttgctcaaa gcacagcttt gaggttgtag ataagactga
    41581 cgaagtcagc tcaaaacact gttttgaggt tgcagataga actgacgaag tcagtaacca
    41641 cacctacggc aaagtgaatc tgaagtggtt tgaagagagt acaacttgtc ttttagaaaa
    41701 ggagcctaca atgaaagtct ttcagcatgt aaatatcgtg acttgtgatc aaaatttcca
    41761 tgtttatctt gatggaatct tagcagtcaa ggattctcaa atcgtctatg tcggtcaaga
    41821 taagccagcg tttttagaac aagctgagca gattatagac tatcagggag cttggattat
    41881 gcctggtttg gtcaattgtc acacccattc tgcaatgaca ggtctgagag ggatccgaga
    41941 tgacagcaat ctccatgaat ggctcaatga ctatatctgg ccagcagaat ctgagtttac
    42001 tcccgacatg actaccaatg cggtcaaaga agccttgaca gagatgctcc agtcaggaac
    42061 aacaaccttt aacgatatgt ataatcccag tggtgtggat atccagcaaa tttatcaggc
    42121 ggtgaaaact tccaagatgc gttgttattt ttctccgact ctcttttctt cagagacaga
    42181 aacaactgct gagactataa gcagaactcg atccatcata gacgaaatct taaaatataa
    42241 aaatccaaat ttcaaggtta tggtagcacc tcattctccg tatagctgca gtagagactt
    42301 gctggaagcg agtttggaaa tggcaaaaga gctaaatatt ccgctccatg tccatgtggc
    42361 ggagaccaag gaggagtcag gaattatcct caaacgatac ggcaaacgcc cccttgcttt
    42421 tcttgaagaa ctgggttatt tagatcatcc gtccgtattt gctcacgggg tcgaattaaa
    42481 cgagagagaa attgaacgct tggcatcttc tcaagtggct atcgcccaca atcctatcag
    42541 taacctcaaa ctggcatcag gaattgctcc aattatccag ctccaaaaag cgggagtagc
    42601 agtcggaatt gcgactgact cggttgcttc caataacaat ctagatatgt ttgaggaagg
    42661 aaggactgca gctcttcttc agaagatgaa aagtggggat gccagccagt ttccaatcga
    42721 aacagctctc aaggtactga caatcgaagg ggctaaggtc cttggaatgg aaaatcagat
    42781 aggaagtctg gaagtcggca agcaagcaga ttttctggtc attcaaccac aagggaaaat
    42841 tcatctccaa cctcaggaaa atatgctgtc tcacctggtt tatgcagtta aatctagtga
    42901 tgtagatgat gtttatatcg ccggagaaca ggttgttaag caaggtcaag tcctgacagt
    42961 agaactttaa aagaaaa
//
LOCUS       DAVLTT010000014        41290 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLTT010000014 DAVLTT010000000
VERSION     DAVLTT010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41290
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.014"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..527
                     /locus_tag="VYN15_000783"
     CDS             <1..527
                     /locus_tag="VYN15_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1452137.1"
                     /translation="GIYRVEGENGSGKSTLLQLLAGLETFDSGLKNCVSKDVLYLDTN
                     QLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINTFFDNKIGDNYMTASTGTKFKLGLS
                     LIFAKNWDYIFIDETLSTVDARSIDMIAKRLISMKESSTIIYVSHNLLNQELISKSQR
                     ILIEEGRVYEISNK"
     gene            508..999
                     /locus_tag="VYN15_000784"
     CDS             508..999
                     /locus_tag="VYN15_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452138.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            1379..3532
                     /locus_tag="VYN15_000785"
     CDS             1379..3532
                     /locus_tag="VYN15_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1452139.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3545..4894
                     /locus_tag="VYN15_000786"
     CDS             3545..4894
                     /locus_tag="VYN15_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV1452140.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            5064..5771
                     /locus_tag="VYN15_000787"
     CDS             5064..5771
                     /locus_tag="VYN15_000787"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV1452141.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5973..9698
                     /locus_tag="VYN15_000788"
     CDS             5973..9698
                     /locus_tag="VYN15_000788"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV1452142.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYISMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVAREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEATLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIVRGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9791..11233
                     /locus_tag="VYN15_000789"
     CDS             9791..11233
                     /locus_tag="VYN15_000789"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV1452143.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11270..12292
                     /locus_tag="VYN15_000790"
     CDS             11270..12292
                     /locus_tag="VYN15_000790"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV1452144.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12289..12834
                     /gene="purN"
                     /locus_tag="VYN15_000791"
     CDS             12289..12834
                     /gene="purN"
                     /locus_tag="VYN15_000791"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV1452145.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12918..13427
                     /locus_tag="VYN15_000792"
     CDS             12918..13427
                     /locus_tag="VYN15_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1452146.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSNLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13452..14999
                     /gene="purH"
                     /locus_tag="VYN15_000793"
     CDS             13452..14999
                     /gene="purH"
                     /locus_tag="VYN15_000793"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV1452147.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            15121..16383
                     /gene="purD"
                     /locus_tag="VYN15_000794"
     CDS             15121..16383
                     /gene="purD"
                     /locus_tag="VYN15_000794"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV1452148.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVIYAGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNITDILDGKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16786..17274
                     /gene="purE"
                     /locus_tag="VYN15_000795"
     CDS             16786..17274
                     /gene="purE"
                     /locus_tag="VYN15_000795"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV1452149.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAAIFALRLLSVEDKSIADALANFAEEQGKIAEESTNE
                     LI"
     gene            17261..18352
                     /gene="purK"
                     /locus_tag="VYN15_000796"
     CDS             17261..18352
                     /gene="purK"
                     /locus_tag="VYN15_000796"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV1452150.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLAERCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVSDSVDELGEGIDF"
     gene            18362..18589
                     /locus_tag="VYN15_000797"
     CDS             18362..18589
                     /locus_tag="VYN15_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV1452151.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            18652..19950
                     /gene="purB"
                     /locus_tag="VYN15_000798"
     CDS             18652..19950
                     /gene="purB"
                     /locus_tag="VYN15_000798"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV1452152.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(20005..23943)
                     /gene="strH"
                     /locus_tag="VYN15_000799"
     CDS             complement(20005..23943)
                     /gene="strH"
                     /locus_tag="VYN15_000799"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1452153.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYDSDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLLTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPRQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(24257..24973)
                     /locus_tag="VYN15_000800"
     CDS             complement(24257..24973)
                     /locus_tag="VYN15_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1452154.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            25321..27108
                     /locus_tag="VYN15_000801"
     CDS             25321..27108
                     /locus_tag="VYN15_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV1452155.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            27105..27581
                     /locus_tag="VYN15_000802"
     CDS             27105..27581
                     /locus_tag="VYN15_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1452156.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27609..28514
                     /locus_tag="VYN15_000803"
     CDS             27609..28514
                     /locus_tag="VYN15_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1452157.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAQKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            28501..29316
                     /locus_tag="VYN15_000804"
     CDS             28501..29316
                     /locus_tag="VYN15_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1452158.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            29323..29727
                     /locus_tag="VYN15_000805"
     CDS             29323..29727
                     /locus_tag="VYN15_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1452159.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            30026..31192
                     /locus_tag="VYN15_000806"
     CDS             30026..31192
                     /locus_tag="VYN15_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV1452160.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            31308..32345
                     /locus_tag="VYN15_000807"
     CDS             31308..32345
                     /locus_tag="VYN15_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV1452161.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            32552..33406
                     /locus_tag="VYN15_000808"
     CDS             32552..33406
                     /locus_tag="VYN15_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1452162.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEAFAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKEELLTIVQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            33556..33813
                     /locus_tag="VYN15_000809"
     CDS             33556..33813
                     /locus_tag="VYN15_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV1452163.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(34143..34235)
                     /locus_tag="VYN15_000810"
                     /pseudo
     CDS             complement(34143..34235)
                     /locus_tag="VYN15_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(34271..34567)
                     /locus_tag="VYN15_000811"
                     /pseudo
     CDS             complement(34271..34567)
                     /locus_tag="VYN15_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(34557..34718)
                     /locus_tag="VYN15_000812"
     CDS             complement(34557..34718)
                     /locus_tag="VYN15_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV1452164.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            34788..35552
                     /locus_tag="VYN15_000813"
     CDS             34788..35552
                     /locus_tag="VYN15_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV1452165.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLK
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(35792..35944)
                     /locus_tag="VYN15_000814"
     CDS             complement(35792..35944)
                     /locus_tag="VYN15_000814"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452166.1"
                     /translation="MRTKASLRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTAR"
     gene            36162..37541
                     /locus_tag="VYN15_000815"
     CDS             36162..37541
                     /locus_tag="VYN15_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1452167.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            37555..38220
                     /locus_tag="VYN15_000816"
     CDS             37555..38220
                     /locus_tag="VYN15_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV1452168.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            38355..38558
                     /locus_tag="VYN15_000817"
     CDS             38355..38558
                     /locus_tag="VYN15_000817"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452169.1"
                     /translation="MKIKDQTRKLATGCSKQCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHCFEVADRTDEVSNIYTARRR"
     gene            38620..39159
                     /locus_tag="VYN15_000818"
     CDS             38620..39159
                     /locus_tag="VYN15_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1452170.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQEDKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQEFESKGQEVDVFVTNFVYEKEGQSCKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YIMMHSLIYRTDLLRASQF"
     gene            39226..39636
                     /locus_tag="VYN15_000819"
     CDS             39226..39636
                     /locus_tag="VYN15_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1452171.1"
                     /translation="MYYLPVDFYRYLIGREGQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQENPKVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            39752..>41290
                     /gene="pavB"
                     /locus_tag="VYN15_000820"
     CDS             39752..>41290
                     /gene="pavB"
                     /locus_tag="VYN15_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV1452172.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQENPELTDALKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGEAKNPALSPLGENVKTKGQYFYQVALD
                     GNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLTNLVATKKVTININGLISK
                     ETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVNHVIPYELFAGDGMLTRLLLKAS
                     DKAPW"
BASE COUNT        11445 a         7977 c         9572 g        12296 t
ORIGIN      
        1 agggaattta cagagttgaa ggagagaatg gttcaggaaa gagcaccctt ctacaacttt
       61 tagctgggct agagactttt gatagtggtt taaagaattg tgtctccaaa gatgtactat
      121 accttgatac caatcagctt ggggttgttc catttactat agaagaaaat ttgcagttgt
      181 tgtgtgattc ttttcaaatc catctatcat ttgaggataa agaacaaatt aatacttttt
      241 ttgataataa aatcggagat aactatatga cagcatctac tggaacaaaa ttcaaattag
      301 gcttatcctt aatttttgct aaaaattggg attatatttt tattgatgag actttatcaa
      361 cagtggatgc aagaagtatt gatatgattg ctaaacgctt aatttccatg aaagaaagct
      421 ctactattat atatgtatct cataatttat tgaatcaaga attgattagc aaatctcaaa
      481 ggattttaat agaggaagga cgggtttatg aaatttcaaa caaataatag tttatacaaa
      541 ttaatgaatc tgattattta tctttttctt ttatatttgt ttattgattt actgatgaag
      601 tcgggaattt tagatgaaca aattgataaa ttatctgaac tatctaatct ttttacaatt
      661 aaaatagaaa caatattgac agtgatttct gttgttttca catttatagc aactcttatt
      721 gaatatggat tttctctctt tctgattaca ttattttttg ataagaataa gaggaacttt
      781 ggagatattc ttttatctaa aaatataacc ttaagtttta gcattttact ttgttattta
      841 tttaatccat cggatataaa gtttgcctat ttcagcgtat tgacagtatt actaattggg
      901 ataacaaatt atgcgagatt taaaaattta agattgacag tagtgttttc tgtaccattt
      961 ttatttaatg ctataatgtc tattataaat agtttttaga aatactaaaa tttttttctt
     1021 tacttaataa tgatatgaaa tcatttcggt tttgttaact tgtaattctt atattttcta
     1081 ggtagaacgt ttgttctgcc tattttttta tccaaaaagt gcagttggga gggagatagg
     1141 ctcatttggg aaggaagtcc agtttttgtt tagtgattgg ggtaagatag ttgttatcag
     1201 atgagtttat actcttcgaa aatcaaattc aaaccacgtc aacgtcgcct tgccgtatat
     1261 atgtgactga cttcgtcagt cctatctaca acctcaaaac agtgttttga gcagcctgcg
     1321 gctagtttcc tagtttgctc tttgattttc attgagtatt agggaaaagg agatgaatat
     1381 gaaatttggg aaacgtcact atcgtccgca agtggatcag atggactgcg gtgtagcttc
     1441 attagccatg gtttttggct actatggtag ttattatttt ttggctcact tgcgagaatt
     1501 ggctaagacg accatggatg ggacgacggc tttgggcttg gtcaaggtgg cagaggagat
     1561 tggttttgag acgcgagcca ttaaggcgga tatgacgctt tttgacttgc cggatttgac
     1621 ttttcctttt gttgcccatg tgcttaagga agggaaattg ctccactact atgtggtgac
     1681 tgggcaggat aaggatagca ttcatattgc cgatccagat cccggggtga aattgaccaa
     1741 actgccacgt gagcgttttg aggaagaatg gacaggagtg actcttttta tggcacctag
     1801 tccagactat aagcctcata aggaacaaaa aaatggtctg ctctctttta tccctatatt
     1861 agtgaagcag cgtggcttga ttgccaatat cgttttggca acactcttgg taaccgtgat
     1921 taacattgtg ggttcttatt atctgcagtc tatcattgat acctatgtgc cagatcagat
     1981 gcgttcgaca ctagggatta tttctattgg gctagtcatc gtctacatcc tccagcaaat
     2041 cttgtcttac gctcaggagt atctcttgct tgttttgggg caacgcttgt cgattgacgt
     2101 gattttgtcc tatatcaagc atgtttttca cctccctatg tccttctttg cgacacgcag
     2161 gacaggggag atcgtgtctc gttttacaga tgctaacagt atcatcgatg cgctggcttc
     2221 gaccatcctt tcgattttcc tagatgtgtc aacggttgtc attatttccc ttgttctatt
     2281 ttcacaaaat accaatctct ttttcatgac tttattggcg cttcctatct acacagtgat
     2341 tatctttgcc tttatgaagc cgtttgaaaa gatgaatcgg gataccatgg aagccaatgc
     2401 ggttctgtct tcttctatca ttgaggacat caacggtatt gagactatca agtccttgac
     2461 cagtgaaagt cagcgttacc aaaaaattga caaggaattt gtggattatc tgaagaaatc
     2521 ctttacctat agtcgagcag agagtcagca aaaggctctg aaaaaggttg cccatctctt
     2581 gcttaatgtc ggcattctct ggatgggggc tgttctggtc atggatggca agatgagttt
     2641 ggggcagttg attacctata ataccttgct ggtttacttt accaatcctt tggaaaatat
     2701 catcaatctg caaaccaagc ttcagacagc gcaggttgcc aataaccgtc taaatgaagt
     2761 gtatctagta gcttctgagt ttgaggagaa gaaaacagtt gaggatttga gcttgatgaa
     2821 gggagatatg accttcaagc aggttcatta caagtatggc tatggtcgag acgtcttgtc
     2881 ggatatcaat ttaaccgttc cccaagggtc taaggtggct tttgtgggga tttcagggtc
     2941 aggtaagacg actttggcca agatgatggt taatttttac gacccaagtc aaggggagat
     3001 tagtctgggt ggtgtcaatc tcaatcagat tgataaaaaa gccctgcgcc agtacatcaa
     3061 ctatctgcct caacagccct atgtctttaa cggaacgatt ttggagaatc ttcttttggg
     3121 agccaaggag gggacgacac aggaagatat cttacgggcg gtcgaattgg cagagattcg
     3181 agaggatatc gagcgcatgc cactgaatta tcagacagaa ttgacttcgg atggggcagg
     3241 gatttcaggt ggtcaacgtc agagaatcgc tttggcgcgt gctctcttga cagatgcgcc
     3301 ggtcttgatt ttggatgagg cgactagcag tttggatatt ttgacagaga agcggattgt
     3361 cgataatctc attgctttgg acaagacctt gattttcatt gctcaccgct tgactattgc
     3421 tgagcggaca gagaaggtgg ttgtcttgga tcagggcaag attgtcgaag aaggaaagca
     3481 tgctgatttg cttgcacagg gaggctttta cgcccatttg gtcaatagct agaaagagga
     3541 gaggatgaaa ccagaatttt tagaaagtgc ggagttttat aatcgtcgtt accataattt
     3601 ttccagtagt gtgattgtac ccatggccct tctgctcgtg tttttacttg gctttgcaac
     3661 tgttgcagag aaggagatga gtttgtccac tagagctact gtcgaaccca gtcgtatcct
     3721 tgcaaatatc cagtcaacta gcaacaatcg tattcttgtc aatcatttgg aagaaaataa
     3781 gctggttaag aagggggatc ttttggttca ataccaagaa ggggcagagg gtgtccaagc
     3841 ggagtcctat gccagtcagt tggacatgct aaaggatcaa aaaaagcaat tggagtatct
     3901 gcaaaagagc ctgcaagaag gggagaacca ctttccagag gaggataagt ttggctacca
     3961 agccaccttt cgcgactaca tcagtcaagc aggcagtctt agggctagta catcgcaaca
     4021 aaatgagacc atcgcgtccc agaatgcagc agctagccaa acccaagccg aaatcggcaa
     4081 cctcatcagt caaacagagg ctaaaattcg cgattaccag acagctaagt cagctattga
     4141 aacaggtgct tccttggccg gtcagaatct agcctactct ctttaccagt cctacaagtc
     4201 tcagggcgaa gaaaatcccc aaactaaggt tcaggcagtt gcacaggttg aagcacagat
     4261 ttctcagtta gaatctagtc ttgctactta ccgtgtccag tatgcaggtt caggtaccca
     4321 gcaagcctat gcgtcagggt taagcagtca attggaatcc cttaaatccc aacatttggc
     4381 aaaggttggt caggaattga cccttctagc ccagaaaatc ttggaggcag agtcaggtaa
     4441 gaaggtacag ggaaatcttt tagacaaggg gaaaattacg gcgagtgagg atggggtgct
     4501 tcatcttaat cctgagacca gtgattctag catggttgca gaaggtgccc tactagccca
     4561 actttatcca tctttggaaa gagaagggaa agccaaactc acagcctatc taagttcaaa
     4621 agatgtagca agaatcaagg tcggtgattc tgttcgctat actacgactc atgatgccgg
     4681 gaatcaactt ttcctagatt ctactattac aagtattgat gcgacagcta ctaagactga
     4741 gaaagggaat ttctttaaaa tcgaggcgga gactaatcta acttcggagc aggctgaaaa
     4801 acttaggtac ggggtggaag gccgcttgca gatgattacg ggcaagaaaa gttatctacg
     4861 ttattatttg gatcaatttt tgaacaaaga gtaatgttcg tgtttttaga gttaaataat
     4921 ttttaaactg tgagaaagat tcttcttgca gttttttctt tacaattttt aaaaaacatc
     4981 tgctatttat tcggttaaat tcttgtgttt tttggttttt tgtggtaaaa tgtgctcaag
     5041 taatacgaaa ggcgaacttt aaaatgtcaa aacaattgat ctattcggga aaagctaaag
     5101 atatctatac aactgaggat gaaaatctta ttatttcaac ttacaaggac caggcgactg
     5161 ctttcaacgg tgtcaagaag gagcagattg caggtaaggg agtcttgaat aatcagattt
     5221 catcttttat ttttgagaaa ttaaatgcgg ctggtgtggc gactcacttt gtggagaaac
     5281 tttcagacac ggaacaactc aataaaaagg ttaagattat tcctttggaa gtcgtgctcc
     5341 gcaactatac tgctggttcc ttttcaaaac gttttggtgt ggatgaggga atcgccttgg
     5401 agactccgat tgtcgaattt tactacaaaa atgatgattt ggatgatcca tttatcaatg
     5461 atgagcatgt gaaattccta cagattgcgg atgaccagca gattgcctac ttgaaggaag
     5521 aaacgcgtcg tatcaatgaa ctattgaaag tctggtttgc tgagattggg cttaaattga
     5581 ttgactttaa gctagagttc ggttttgaca aggatggcaa gattatcttg gcagacgaat
     5641 tttcaccaga taactgccgc ttgtgggatg ctgatggcaa ccacatggat aaggatgttt
     5701 tccgtagagg attgggagaa ctaaccgacg tttatgagat tgtttgggaa aagttgcagg
     5761 aattgaaata atctgtttgc aatggaaaac cttcgtctct caactaaaag gactcaggct
     5821 gaaaaggtcc cccagacctt ttcactctgt agagaactag gtgaactaac cgatgtttac
     5881 gaaattgtct gggaaaagtt gcagggttta aaataacaac ctcaaggctg tttgggaata
     5941 ttgcaagagc tgaaataaag gaataagaat tgatggataa acgtattttt gttgaaaaaa
     6001 aggctgattt tcaggtcaag tcagagagtt tggttagaga gctccagcac aacttgggac
     6061 tgtcaagctt gaaaagtatt cgtattgtgc aagtatatga tgtatttgac ttggttgagg
     6121 acttgtttgc acctgcagag aagcacattt tctctgagca ggtaaccgac catgttttag
     6181 atgaagtatc tgtgcaggcg gatcttgcta actatgcttt ctttgccatt gaaagtctgc
     6241 cagggcagtt tgaccagcgt gcagcttcgt cacaggaagc cttgcttttg ttgggaagtt
     6301 cgagtgacgt gacagtcaac acagcccaac tttacttggt gaataaagat attgatgcga
     6361 ctgagttgga agctgtcaaa aactacctgc tcaatccagt tgattctcgt ttcaaggata
     6421 tcacgacagg gattgccaag caggagtttt cagagtcaga caagaccatt ccaaaattga
     6481 ctttctttga aagctataca gcagaagact ttgctcgcta caaggccgaa caagggatgg
     6541 ccatggaagt ggatgatttg ctctttatcc aagactactt taagtcaatc gggcgcgtgc
     6601 caactgagac tgaactcaag gttttggaca cttactggtc tgaccactgc cgtcatacga
     6661 cttttgagac agagttgaaa cacatcgact tttcagcttc taaatttcaa aagcaattgc
     6721 agtcaaccta tgacaagtat atttccatgc gcgaggaatt aggtcggtct gaaaaaccac
     6781 aaaccttgat ggatatggcg actattttcg gtcgttatga gcgtgctaat ggacgattgg
     6841 atgatatgga agtctctgac gaaatcaatg cctgctcagt tgaaattgaa gtggacgttg
     6901 atggtgtcaa ggaaccttgg ctcctcatgt ttaaaaacga aacccacaac catccaacag
     6961 aaattgagcc atttggtgga gcggctacct gtatcggtgg agctattcgt gatccgttgt
     7021 caggccgttc ctatgtttac caagccatgc gtatttcagg tgctggtgat attacagcac
     7081 cgatttcgga aactcgtgct gggaaattgc cacaacaagt catttctaaa acagcagctc
     7141 atggttattc ttcatatggt aaccagattg ggcttgcaac aacctacgtt cgtgaatact
     7201 tccacccagg ttttgtagct aaacgtatgg aacttggtgc cgttgttggt gcggctccca
     7261 agggcaatgt tgcccgtgaa aaacctgaag caggtgatgt gatcatcctt ctcggaggca
     7321 aaacaggtcg tgatggtgtc ggtggtgcga cgggctcttc taaagttcaa acagttgagt
     7381 ctgtagagac tgctggtgct gaggttcaaa aaggaaatgc catcgaagaa cgcaagattc
     7441 agcgcctctt ccgtaatggc aatgtcactc gtctgatcaa gaagtccaat gactttgggg
     7501 caggcggtgt ctgtgtggct atcggtgaat tggcagacgg tcttgaaatc gacctcaaca
     7561 aggtgcctct taaataccag ggcttgaatg gtacagaaat tgccatctct gaatcacaag
     7621 aacggatggc ggtcgtggtt cgtcctgaag atgtggatac cttcgttgcc gaatgtaaca
     7681 aagaaaatat tgatgctgtt gtggtggcga cagtaactga aaaaccaaat cttgtcatgc
     7741 actggaatgg tgagacaatc gttgacttgg agcgtcgttt ccttgacacc aatggtgtgc
     7801 gcgtggttgt cgatgccaaa gttgtggaca aggatgtcaa actcccagaa gagcgtcaaa
     7861 catctgctga aacactggaa tcagataccc ttacggttct atctgacctc aaccatgcaa
     7921 gtcaaaaagg attacagact gtctttgact gctctgttgg acgctcaacg gttaatcacc
     7981 cacttggtgg tcgttaccaa ctcacaccaa ctgaggcatc tgtgcagaaa ttgccagttc
     8041 aacacggtgt gactcatact gcgtcggtca ttgctcaagg tttcaaccca tatgtagctg
     8101 aatggtctcc ataccacggt gctgcttatg cggttatcga agcaactgct cgtttggtgg
     8161 ctgctggtgc caactggtcc aaggctcgtt tctcttacca agaatatttc gagcggatgg
     8221 acaagcaagc agagcgtttt ggtcagccag tagccgccct tctaggctct attgaagctc
     8281 agattcaact tggcttgcca tctatcggtg gtaaggactc catgtctggt acctttgaag
     8341 aattgaccgt tccgccaacc ttggttgcct ttggggtgac gacggcagat agccgtaagg
     8401 tgctctctcc agaatttaaa gctgttgggg aaaatatcta ctacatccca ggtcaagccc
     8461 tctctgcaga gattgatttt gacttgatta agaaaaattt tgctcagttt gaagccatcc
     8521 aagctgacca taaagtgaca tctgcatcag ctgtcaaata cggtggtgta gttgaaagtt
     8581 tggctcttgc tacctttgga aactatattg gtgcagaggc gaccttgcct gaacttaaaa
     8641 cagctttgac agctcaatta ggcggctttg tcttcacatc tcctgaagaa attgctggag
     8701 tagagaaggt tggacaaacg aaagcagact ttacactgac tgtcaacggt gtgaagctag
     8761 atggacacaa gcttgacagt gcatttcaag ggacattgga agaagtttac ccaacagaat
     8821 ttacccaagc gaaagaacta gaagaagtac cagctgtggc atcagatgtt gtgattaaag
     8881 ccaaagaaaa ggttgaaaaa cctgtggttt acatcccagt ctttccagga accaactcag
     8941 aatatgattc agctaaggcc ttcgaaaaag aaggtgcaga ggtcaatttg gtgccattcg
     9001 tgaccttgaa tgaagaagct attgtcaagt cagttgaaac tatggttgac aatatcgaca
     9061 agactaatat tctcttcttt gccggtggat tctcggctgc ggatgaacca gatggttcag
     9121 ctaagtttat cgtcaatatc ctgcttaatg aaaaagtgcg tgtggctatt gatagcttta
     9181 tcgtccgtgg tggcttgatt atcggtattt gtaatggatt ccaagcctta gtcaaatcgg
     9241 gtctcctacc atacggaaac tttgaagatg ctaacagtac tagtccaacc ctcttctaca
     9301 atgatgccaa ccaacacgtg gccaagatgg tggaaactcg cattgccaat accaactcac
     9361 catggttggc tggtgtgcaa gtgggcgata tccacgctat tcctgtttcg cacggtgaag
     9421 ggaagtttgt cgtgacggct gaggaatttg cagagctccg tgacaatgga caaattttca
     9481 gccaatacgt tgactttaac ggtaaaccaa gtatggattc taagtacaat ccgaatggtt
     9541 ctgtccatgc catcgaagga attaccagca agaatggtca aatcatcggt aagatgggcc
     9601 actcagaacg ttatgaggat ggtcttttcc aaaatatccc aggcaataaa gaccagcacc
     9661 tgttcgcgtc agcggttaaa catttcactg gaaaataaga cttacagatt ttctaataga
     9721 tagtatcagt aatgtaaaag tcatgtaaat ctagctcttg atgattacaa atgaaaatta
     9781 ggtataaaaa atgacatacg aagtaaaatc tcttaatgaa gaatgtggtg ttttcggtat
     9841 ttggggacat ccagatgctg ctaagttgac ctattttgga ctccacagtc ttcaacaccg
     9901 tggtcaggag ggggcaggaa tcctctccaa tgatcaagga caactgaagc gccatcgtga
     9961 catggggctt ttatcagaag ttttcagaaa tccagccaat ttggataaat tgacaggagc
    10021 tggtgcgatt gggcatgtgc gttatgcgac tgctggcgaa gcttctgttg ataacatcca
    10081 acccttcctc ttccgttttc acgatatgca gtttggtttg gctcataatg gaaatctgac
    10141 caatgcagcc tctctcaaga aagaactgga acaaagagga gcaattttca gcgcgacttc
    10201 ggactctgaa atcttggctc acctcattcg tcgcagtcat aatcctagcc tgatgggcaa
    10261 aatcaaggaa gcgctcagcc ttgtcaaagg tggttttgcc tatatcttgc tgtttgagga
    10321 caagttgatt gcggctcttg accctaatgg ctttcgtccg ctttctatcg ggaaaatggc
    10381 caacggagcg gtggttgttt cctctgaaac ctgtgctttt gaggtcattg gtgccgagtg
    10441 gatttgtgat ttgaagccag gtgagattgt gatcattgat gacgagggca ttcagtatga
    10501 cagctataca gatgataccc agttggcgat ttgttctatg gagtatatct actttgcccg
    10561 ccctgattct aatatccacg gtgtcaatgt ccatacggca cgtaagagaa tgggagcgca
    10621 attggcgcga gaatttaagc atgaggcaga tattgtagtt ggtgtgccca attcttccct
    10681 aagcgcggct atgggatttg cggaagaatc aggcttacca aatgaaatgg gtctgatcaa
    10741 aaaccaatac acccagcgaa cttttatcca accgactcaa gaattgcggg agcaaggagt
    10801 gcggatgaaa ctgtctgctg tttcgggtgt tgtcaaaggc aaacgtgtgg tcatggtgga
    10861 tgattccatt gtacgtggaa caacctctcg tcgtatcgtt cagctcttga aagaagcggg
    10921 tgcgactgag gttcacgttg ccattggaag tcctgcacta gcgtatccat gtttctacgg
    10981 gattgatatc cagacccgtc aggagctgat tgcagccaat catacggtcg aagaaactcg
    11041 ccaaatcatt ggtgcggaca gtctgactta tctttcaatt gatggcttga ttgagtcgat
    11101 tggtatcgaa acagatgcgc cgaacggtgg tctctgtgtc gcttactttg acggtgacta
    11161 cccaacgcct ctctatgatt acgaagaaga ctatcgtaga agtttggaag aaaagaccag
    11221 tttttacaag taggcgacag attctccatt aaagaaaagg aaaaaacaaa tgacaaataa
    11281 aaatgcatat gcccagtcgg gtgtggatgt tgaagcgggt tatgaagttg ttgaacggat
    11341 taaaaagcac gtggcccgta cggagcgtgc aggtgtcatg ggagctcttg gtggctttgg
    11401 tggtatgttt gacctttcca agactggggt taaagaaccc gtcttgattt cagggactga
    11461 cggtgtcgga accaagctca tgttggctat caagtacgac aagcacgata ccatcgggca
    11521 ggactgtgtg gccatgtgtg tcaacgacat cattgctgca ggtgcggaac ccctctattt
    11581 tctcgactac gtagcgacag ggaagaatga accagctaag ctagaacaag tggttgctgg
    11641 tgtggcagaa ggttgtgtgc aggctggtgc tgccctcatc ggtggggaaa cggctgaaat
    11701 gccgggcatg tacggcgaag acgactatga cttggctggt tttgcggtcg gtgtggctga
    11761 aaaatctcaa atcattgacg gttcaaaggt ggtagaggga gatgttcttc tcggacttgc
    11821 ttcaagtggg attcactcaa atggttactc tttggttcgt cgtgtctttg cggattacac
    11881 aggtgaggaa gtcctaccag aattggaagg caagaaactt aaggaagttc tacttgagcc
    11941 gactcgtatc tatgtcaagg ctgtcttgcc gctcatcaaa gaagagttgg tcaacggcat
    12001 tgcccacatc acaggtggtg gctttatcga aaatgtccct cgtatgtttg cagatgacct
    12061 agctgctgaa attgatgaaa gcaaagttcc agtgcttcca attttcaaag cccttgaaaa
    12121 atatggtcag attaaacacg aagaaatgtt tgaaatcttc aatatgggtg tgggactcat
    12181 gttggcggtc agccctgaaa atgtagagcg tgtaaaagaa ttgttggatg aagcagtcta
    12241 tgaaattggt cgcatcgtca agaaagaaaa cgaaagtgtc attatcaaat gaaaaaaata
    12301 gcggtttttg cctctggtaa tggctcaaat tttcaggtga ttgccgaaga atttccagtg
    12361 gagtttgtct tttcagacca tcgtgatgcc tatgtgcttg agcgtgcaaa gcagctcggc
    12421 gttctgtcct atgcttttga actcaaggag tttgagagca aggcagacta cgaagcagcc
    12481 cttgtcgaac tcttggaaga acaccagatt gacttggttt gcctagcagg ctacatgaaa
    12541 atcgttggac caaccttatt gtcggcttat gaaggtcgga ttgtcaacat tcatccagcc
    12601 tacttgccag aatttccagg agctcatggg attgaggatg cttggaatgc tggcgtgggt
    12661 cagtctggtg tgaccattca ctgggtggat tcgggtgtgg atacaggcca ggtcatcaaa
    12721 caggttcgtg tgccacgact agctgatgat accattgaca gatttgaagc tcgcatccat
    12781 gaagcagagt acaggttgta tccggaagta gtgaaggctc tatttacaga ttgacttttt
    12841 gatgattcat atgatatctt tgattttaaa ttggagtcag tgtttgttga agacggcttc
    12901 aaacggaggt atttgtaatg ttagaatcta aaaaaacaac tcgatatgta ttttatgtct
    12961 atctgatgtt attaacttgg ggaatcttat ttaagtttga aacaaatcct gaatttatag
    13021 catttttctt agctccaagg tatatcaatt ggattccatt ttcagaacca ctaatagtcg
    13081 atggaaaaat tgtttttgct gaaatgttat ttaatctgat tttctttatt ccattaggtg
    13141 tttgtttccc tttgataaaa actaatttat ctaatttaag aatagtcggg acaggtttct
    13201 tgattagttt attgtttgag tgcttacagt atattttagc aataggtata acagatataa
    13261 cggatttgac tttaaatacg ctaggtgtct gtgtaggctt actgatttat caaattttta
    13321 taagagtgtt caaatcacag actagaaaat ggatcaatat cttaggtatg cttagccttg
    13381 gttttgctta tcttgtttta ctgttactgc atttaattgg tgtttaacta atgattaaaa
    13441 aggagaatat aatgactaaa cgcgtcttaa tcagcgtctc agacaaagcg ggcattgttg
    13501 aatttgccca agaactcaaa aaacttggtt gggagattat ctcaacaggt ggaactaagg
    13561 ttgcccttga taatgctggg gtggatacca ttgctatcga tgatgtgact ggtttcccag
    13621 aaatgatgga cggtcgtgtg aagaccctcc acccaaatat ccacggaggg cttctcgctc
    13681 gtcgtgactt ggatagccac ttggaagcgg ctaaggacaa caagattgag ctcattgacc
    13741 ttgtggtggt caacctttac ccatttaagg aaactatcct taaaccagat gtgacttatg
    13801 ctgatgcagt tgaaaatatc gatattggtg ggccatctat gcttcgttca gcagcgaaaa
    13861 atcatgccag tgttacagtt gtggtagatc ctgctgacta cgctgtggtt ttggatgaat
    13921 tggcagcaaa cggcgaaacc tcttatgaaa ctcgccaacg tttagcagcc aaagtatttc
    13981 gtcacacagc ggcttatgac gccttgattg cagaatactt cacagctcaa gtgggtgaaa
    14041 gcaagcctga aaaactcact ttgacttatg acctcaagca accaatgcgt tacggtgaga
    14101 atcctcaaca agacgcggac ttttaccaga aagctttgcc tacagactac tccattgctt
    14161 cagccaaaca gctcaacggg aaagaattgt catttaataa tatccgtgat gcagatgctg
    14221 ctatccgtat catccgtgac ttcaaagata gtccaaccgt tgtggctctc aaacacatga
    14281 atccatgtgg aattggtcaa gctgatgaca tcgagactgc ttgggactac gcttatgagt
    14341 ctgacccagt gtctatcttt ggtgggattg tcgtcctcaa ccgtgaggtg gatgctgcga
    14401 cagctgagaa gatgcacggc gttttcctcg aaatcatcat tgcaccaagc tatacggatg
    14461 aagcgctagc cattttgatc aataaaaaga aaaacttgcg tatccttgcc ttgccattta
    14521 atgctcaaga ggctagcgaa gtggaagcag aatacacagg tgtagtcggt ggacttctcg
    14581 tgcaaaatca agacgtggtc aaggaaagcc cagctgactg gcaagtggtg accaaacgtc
    14641 agccaaccga gacagaagcg actgctcttg agttcgcttg gaaggctatc aagtacgtca
    14701 aatcaaatgg tattatcgtg accaacgacc acatgacact tggtgttggt ccaggtcaaa
    14761 ccaaccgtgt ggcttctgtt cgccttgcca ttgaccaagc caaagatcgt ctggacgggg
    14821 cggtccttgc ttcagatgcc ttcttcccat ttgcggataa cgtggaagaa atcgccaaag
    14881 caggaattaa ggccatcatc cagcctggtg gctctgtccg tgaccaagaa tccatcgaag
    14941 cagcggataa atacggcttg actatggtct ttacaggtgt gagacatttt agacattaag
    15001 aagataaaag ggaagaaaac agtttctttc cttttttggc ttaaaatgct aactgaaaca
    15061 agattaaaac gaactttttt gatataatgt tggtaaataa ttcgcaaaag aggttgagga
    15121 atgaaactgc ttgttgtcgg ttctggtggt cgtgagcatg cgattgctaa aaagttactt
    15181 gaatcaaaag acgtggaaaa agtctttgta gctcctggga atgatgggat gactctggat
    15241 ggtttggaat tggtaaatat ctctatttcc gaacattcta aattgattga cttcgcaaag
    15301 accaatgatg ttgcttggac ctttatcggt ccagatgatg cccttgctgc tggtatcgtg
    15361 gatgatttta accaagctgg gcttaaggcc tttggtccga ctagggctgc agcggagctg
    15421 gagtggtcca aggattttgc caaggaaatc atggtcaaat atggtgtttc gacagcagcc
    15481 tatggcacat tttcagattt cgaggaagca aaggcctata tcgaaaagca tggtgcgcct
    15541 atcgtagtca aggcggatgg cttggcgctt gggaagggtg tcgtcgttgc tgagacggtt
    15601 gagcaagcgg tcgaagccgc tcatgagatg cttttggaca ataaatttgg tgactcaggt
    15661 gcgcgcgtgg ttattgagga attccttgaa ggagaggaat tttcactctt tgcctttgtc
    15721 aatggtgata agttctacat catgccaacg gctcaggacc acaaacgtgc ctacgatggc
    15781 gacaaagggc ctaacacggg tggtatgggt gcctatgcgc cagttccaca cttaccacag
    15841 agtgtagttg atacagcggt tgacaccatt gtcaagccag ttctagaagg gatgattaaa
    15901 gaaggtcgcc cttatctagg tgtcatttac gcaggactta tcttgacagc agacgggccg
    15961 aaggtcatcg agttcaactc tcgatttgga gatcctgaaa ctcagattat attgcctcgt
    16021 ttgacatctg attttgcgca aaatatcacg gatattctgg atggcaagga gccaaatatc
    16081 atgtggacgg acaagggtgt gactctgggt gtggttgtcg catccaaggg ctacccgcta
    16141 gactatgaaa ggggcgttga gttgccagcc aagacagaag gcgatgtcat cacctactat
    16201 gcaggggcta agtttgcgga aaatagcaga gcactgctct caaacggcgg acgagtttat
    16261 atgctcgtta ccacagcaga taccgtcaaa gaagcccaag ccagcatcta ccaagaacta
    16321 tcccaacaaa aaatagaagg actcttctac cgaacagata tcggaagcaa ggcaattaag
    16381 taaagatata agaataacgc gccgtagtcg ccaaacacga taatggtcgt cgtggtgaaa
    16441 agaccagaac agtgaatgtt ctggtcaggg ggaaacttgg agaccgtagg ctcaaagttt
    16501 aggaatgaaa ccgaaggttt gcttccgcct ctatcaccta agaccattat caaaaagaaa
    16561 aataaaaatt cacaaaatac gttaatgatc gtatggtttg cgagcgttag cgagctaata
    16621 tagaacaatc accgccgttg tgaaagaacg attggatgat aatccaatcg ttcagggaaa
    16681 ttggaagacc ttgggtttcc aatttaggca tgagacacct ttggtggctg ctgccgtccc
    16741 tcacaagcta aggtgattgt tgaaaaagag gaaaaaggag aagaaatgaa accagtaatt
    16801 tccatcatca tgggctcaaa atccgactgg gcaaccatgc aaaaaacagc agaagtccta
    16861 gaccgcttcg gtgtagccta cgaaaagaaa gttgtttccg cacaccgtac accagacctc
    16921 atgttcaaac atgcagaaga agcccgtagt cgtggcatca agatcatcat cgcaggtgct
    16981 ggtggcgcag cgcatttgcc aggcatggta gctgccaaaa caacccttcc agtcattggt
    17041 gtgccagtca agtctcgtgc tcttagtgga gtggattcac tctattctat cgttcagatg
    17101 ccgggtgggg tgcctgttgc gaccatggct atcggtgaag ctggagcgac taacgcagct
    17161 atctttgccc tccgtctcct ctctgtagaa gataagtcca ttgcggatgc acttgccaac
    17221 tttgctgaag aacaaggaaa aatcgcagag gagtctacca atgagctcat ctaaaacaat
    17281 cggaattatc ggtggcggtc agctgggtca gatgatggcc atttctgcta tctacatggg
    17341 tcataaggtt atcgcgttgg atcctgcagc ggattgccca gcctctcgtg tggcggaaat
    17401 cattgtggcg ccttataacg atgtggatgc ccttcgtcag ctagctgagc gttgcgatgt
    17461 cctgacttat gaatttgaaa atgtcgacgc tgacggtttg gatgccgtta tcaaggatgg
    17521 acaactccct caaggaacag atctgctccg catttcgcaa aatcgtattt ttgaaaagga
    17581 ctttttgtca aacaaggctc aagtcactgt ggcaccctac aaggtcgtga cttctagcct
    17641 agacttggca gatatcgact tgtcgaaaaa ctatgtcctc aagactgcga ctggtggcta
    17701 cgatggtcat ggacaaaagg ttattcgttc agaagcagac ttggaagcag cctatgcgct
    17761 agcagactca gcagactgcg tcttggaaga atttgtcaac tttgaccttg agatttctgt
    17821 catcgtgtca ggaaatggca aggaggtgac gtttttccca gttcaggaaa atatccaccg
    17881 caacaatatc ctgtctaaga ccatcgtacc agcccgcatt tctgaaagtc tagcagacaa
    17941 ggctaaagct atggcagtgc gaatcgcaga acaactcaac ttgtctggaa ctctctgtgt
    18001 ggaaatgttt gcgactgatg atgacgttat tgtcaatgaa atcgccccac gaccacataa
    18061 ctctgggcac tattctattg aagcctgtga tttctctcag tttgacaccc atattctggg
    18121 tgttctcgga gcaccattac cagtcatcaa actccatgcg ccagccgtta tgcttaatgt
    18181 cctcggtcag catgtcgagg ctgctgagca atatgtgaca gaaaattcaa gcgcccacct
    18241 ccacatgtat ggtaaaatag aagcaaagca taatcgtaag atgggacatg tgaccttgtt
    18301 tagtgatgta tcggatagtg tggatgagct tggggaaggg attgattttt aggacaagtc
    18361 tatgatacaa attatcgtta atacatttat tgaaaaggat aagactggag cagttgttga
    18421 agtgttgtat gccagtgctg accaagataa ggtacaagct aaatatgaag aactagctgc
    18481 acaatacccc gaaaattatt tagctatcta tgatgtaccg ctggatacgg atttgaatac
    18541 actagatcat tacccgtctg tgtttattga aaaagaggag tttgagtaga aatcttggtt
    18601 tacctagata gcttattccc aacagcttaa gaagaaagga aaaattaaca catgatcaac
    18661 cgttactctc gccctgagat ggcgaatatt tggagtgaag aaaataaata ccgtgcttgg
    18721 cttgaggtgg aaatcctctc tgacgaggca tgggctgagt tgggggaaat ccctaaggaa
    18781 gatgtggctt tgattcgcaa gaaggcggac tttgacatcg accgtatttt ggaaattgag
    18841 caggagacgc gccacgatgt ggtggctttc acgcgtgcgg tttctgagac tcttggtgaa
    18901 gagcgcaagt gggttcacta tgggttaact tctaccgacg tggtggatac tgcttatggt
    18961 tacctctaca agcaggccaa cgacatcatc cgtcgtgacc ttgaaaactt cactaatatc
    19021 atcgctgaca aggccaagga gcacaagttc accatcatga tggggcgtac tcatggtgtg
    19081 cacgctgagc cgacaacctt tggtcttaaa ttggcaactt ggtacagcga aatgaaacgc
    19141 aatatcgagc gtttcgagca tgcagctgct ggtgtagaag ctggtaagat ttctggtgcg
    19201 gttgggaact ttgccaatat cccaccattt gtagaggagt atgtctgcga taaacttggc
    19261 atccgtgccc aagaaatctc tacacaagtc cttcctcgtg accttcacgc tgagtacttt
    19321 gcggttcttg ccagcattgc gacttcaatc gaacgtatgg cgactgagat tcgtggtcta
    19381 caaaaatctg agcaacgcga agtagaagag ttctttgcta aagggcaaaa agggtcttca
    19441 gcaatgcctc acaaacgcaa cccaatcggt tctgaaaata tgactggtct ggcgcgtgtc
    19501 attcgtggtc acatgattac ggcttatgaa aacgtcgctc tctggcacga acgcgatatt
    19561 tctcactcat cagctgagcg tatcatcaca ccagatacga ccattttgat tgactacatg
    19621 ctcaaccgtt ttggaaatat cgtcaagaac ttgacagtct tcccagaaaa tatgatccga
    19681 aacatgaact cgacttttgg tcttatcttt agccaacggg ctatgttgac attgattgaa
    19741 aaaggcatga cccgtgagca agcctatgac ttggtgcaac caaaaacagc ctactcttgg
    19801 gacaaccaag tagactttaa accacttctt gaggcagatt cagaagtaac atcacgtctc
    19861 actcaagaag aaatcgatga aatcttcaac ccagtttatt acaccaaacg agtggatgat
    19921 atctttgaac gtcttggact aggtgattaa ttaaaaaata aacagcgagc ttcaatctcg
    19981 ctgtttattt tttatcgaaa agacttagtc ttcttttctt ttagtgagtc cataggctgc
    20041 tagtgtggac atgagtcctg cgactactag tcctgcagaa tcgtgagttc ctgtttcagg
    20101 aagttttttc tctgttacca caggagctgg atcttgagga agagctttgc tttcctcagc
    20161 aggagcagtt gatggagctg gttgtcttgg gatttctagt tttggttttt cttcagcaat
    20221 agcggcttgt ccgttttcat cgcctacatg tgttaccata gttccgactt cgactatttg
    20281 agtaacggct tcctgtgcta cgacactatt tacaagtgtt ttcacttcct taccatcggc
    20341 agaagtgctc acagagtaga agttgctacg atgtccattg acgcccttag taatgacttg
    20401 tgtttttcct ttgagtaaga gtggattttc acgagtcact gtggtaaatg gaatttcttc
    20461 tttttggata tccagtctag gttttacctc agtagttggt gcaagaccac tttcatcacc
    20521 cttgtgagtt acaggagcgc caacttcaac cacttggttt ataacttctt tggttacctg
    20581 gctatcaagg actgtttctg ttgtttttcc attttcagtg agtacagaga tgtaatgagt
    20641 tcgttcacct ttgactcctg ctgtgataat attttcctga ccagctggga ggttaggatt
    20701 ttctttcttg ataacttcaa atggaatttc ttcagttctt gtgatgagtt ctggtctggt
    20761 ttcaacattg gcagccactt cattttcatc taggcttcct gaatgagttg cagctggttt
    20821 gaggccttga agagcggctt ttaggttggc tacaagtgtg tcaagctcag cttgtttatt
    20881 acggttgagg ttgtaattta gagctgtttt agctgcgtca agggcctcaa gactttcttt
    20941 actatatcct tctaagtttg taggaatttt agctaattct tcgcggagag cattataatt
    21001 agcacggaag tagtctttgt tgtggtctgc aaaggcagtc atgagttcaa agatttcctc
    21061 ttccttgtat tcagcgcttg gtctatctgc ccagattgaa agcatacttc cgactgttag
    21121 aagatctact tcaggatatt tggtagaagc tagttgattg aatggtgttt ttccagtatt
    21181 ctcaatagct ttcttgagga aaccaccacc atcttctggt ttttgaccaa gaatgtagta
    21241 ccagtcaccg ttggtattca agaatttata gcctttgctt gctaggtatt gaggtgatgc
    21301 gaggttatat ccccaccagc ctttagacca gtaagaaatc aagacatctt tgtcaaactg
    21361 aacatcgtcc ttgtcttcat agtagaagcc atcgttgaag gccattggtt gaagccctct
    21421 ttctttggcc atagctgcga gggtgttggc atattcggca aatttgccat agagttgata
    21481 ccacttgagg tagtaccagc cttgggcact agtcgcatcg ttggcgtatt cgtcagtacc
    21541 aaagttgaaa atctttgttt tacctgcaaa gaagtccatg tatttaccga tgagggcttt
    21601 tacaaagttc atcgcttctt cgtttttcaa gtccatagtt gtttttgaaa ctttatcaaa
    21661 gtgggcttga ggatttttaa tacctaattt ttccatggca accagcatag catccatgtg
    21721 acctggactg ttaatagctg ggatgagacc gatgtcctta gatttagcgt attcaattag
    21781 ctctgttact tctgcctgtg ttagtgcagt accgtttgga tcgtcgtagt aagctttagt
    21841 tccttcgata atagcttttt taacgtcatc actagcatag gtttttccgt tggcagtaat
    21901 ggtcatatca tcgagtagaa agcgaagtcc gtcatttcct agaaggagat ggacatcaga
    21961 atatccgagc tcactggcct tgtctacgat gcgtttgagc tggttcagag taaagtattt
    22021 gcgtccagca tcgattgaga ttaccttgtt tttggcaagt ttttcaacct cacgtttagc
    22081 ttcttcttct ttttgagctt caggcgtgag ggtcaagttg ttgacagttt cttgaagttt
    22141 agcaatggct tgatcaatcg tatcttgttg ggcacggcta aggttgctat cgagagagcg
    22201 aatagctttt tcagcttctt ttacggccgt gacgctttct gcagtataac ggttcaggtc
    22261 ttttggtacc tcgttaagtg cttgctctgc agattcataa tcagctgcga agtattcagc
    22321 gttggcattt gcaaaatgac gcatgagttt gaagaggcgt gatggtgaat aacgtgcaga
    22381 tggagtgtca gcccaagcag ctaccatacc accgatgatt gggatatcag ctccttctgt
    22441 ttttggtaca gaagtgattg gtgtgttttt aataccattg agcccctgat cgagattgta
    22501 ccagccttgg ccatcagcgt ttcgtccaag aacgtagtac caagcatcat tggtattaag
    22561 gatttggtga cctttttcag ctagtagttt agaagaagcg acatcgtagc ctccccaacc
    22621 accagtccac atagaaacga tgatgtcttt gtcaaaacta ccaaagcttg tgtcgctatt
    22681 gtagtagata ccgtcgttaa aggccattgg tttgagaccg tgcgatttta caatacgagc
    22741 gaggtcattg gcgtaggcaa taaatttttc atagcctttt acagggtagc cttcgtttgg
    22801 atagtattta tcagcttgaa gcacactcca acctttagca tctgtcgcat cattggcata
    22861 ttcatcaagt ccgatgttga agatttcagt ctttttcgcg aaataagcag catacttgtc
    22921 gataagggct tttgtaaaag cgacagcttg ttcgttgtca agatcgacag tacgggctga
    22981 ttccttccca aaatagctaa agttagggtt ttggattccc aattctttca tggcattgag
    23041 aatcgcatcc atgtgaccag gactatttac tgtcggaatg agaccgatac ctttatcttt
    23101 ggcatagtta atcagatctg tcatttgact ttctgttaag tgattgccgt ttggatcgtt
    23161 gtaataatca tttgtacctt tttcaatggc gcgtttgaca tcgtcactgt cataggtctt
    23221 gccgttagct gtgatgctca tatcgtccaa catgaaacgg agtccatcat ttccgactaa
    23281 taggtgtaaa tcagtgtagc cataatgttt cgctttatcg atgatttcct tgagctgttc
    23341 tggtgagaaa tatttacgtc cagcatcaat agaaacaatt ttctttttcg ctagtttttc
    23401 atttacagtt gcagcacgtt cctttcctgc ctctgtttcc ggtttgtcag cctctgcttt
    23461 cgcttcatct tttttagctg gtttatcctt gtcagtcttg tctgtatttg actctttaga
    23521 atcaacctct ttcgcttctt cctttttagg gctagcttct tctgcctttt tattagcagt
    23581 ttctttttca gcagaagttg gagttaccac ttctgcttta tcactaggag ttgaactaac
    23641 ttcctcttgt ggtttttctt ctgtttttgg aagactagct accttatcag tagctggagt
    23701 ttctgtttct acagtttttg gagcttctgg ttgaagctct gctttaggtg tttcctcagt
    23761 ccgattttcg gatgattgag gggaatcaga aaccgtatgg atggtcggtt ggttttctgt
    23821 agtagtagga gtaactccat cggctgcaac agtctgtgct tggaaggcaa atccaattag
    23881 aacagaagct gctcctacag cgtatttacg aatagaaaaa cgctgttgtt tttcatgttt
    23941 cattgcaaaa cctcctgatt gcattgttat attgatagcg attatataaa tcaacgcctt
    24001 tattttattt cttatattaa cgagagtcaa gaggagatga caaaaaacta taataagtat
    24061 aaaaaaatat aaaatttaaa cttaagattt cagattggtc gaaaaataca tatatatatc
    24121 tagtataatt tttggttcta tttctataaa atattccaca aattatagaa tcttccaaaa
    24181 ataggtaagc gctacctttt tggtgtggta taataagcat agaaaaagcc cgagcgatta
    24241 ggctcaggct ttcttcttag tgatcacggt cacatgagat aaatttaatc ttgtagtaat
    24301 cagatcgttt gtaagtttca ctgtattcta aaacttggcc agttgattcg agtttggtga
    24361 ttttagtttg taggacagta gggaattgtt catcgactcc gaggactgaa gccgcatgtt
    24421 ctggagttgg aaagactatt tcgttgattt cttcaaagtg ttcatcattc atgtgaatgt
    24481 ggtagtctaa cttgaaacga ttatagatag aactatagta ttcaaggttt ggataatttg
    24541 cgttgatata ttgttctggg atgtaggatg tatggtagat ataaacgaca ccgtttgatt
    24601 cgcggatacg ttcaatcttg tagtagaatt gatcgccgcg tagacccaat ttttccaagt
    24661 aaacaagctt gtttccgcgt tcaattgaaa gaacagttac cttatcatct ttagcattga
    24721 agagttcaat atctgaaaac tctacaagct tgtgtttgcg cgcacgtgaa acgaaggttc
    24781 cttttccttg ttggcggaca atatagccat ctttggcaag gtcgtttaag gcgcgaacaa
    24841 ctgtgataga gctgacatcg tacattgaaa tgagttctgc ttcagtgtaa aatttatctc
    24901 cactgctaaa ctgcccagag atgattttat tttttaattc gtcttttatg tattgatatt
    24961 tgggaattgc catattttta cctctatttt ccttctccat agaaaatttt accataaaag
    25021 cgaaaaaaat agtagtcttt tgaataaaaa attagaataa tagtttgaaa aattaagcga
    25081 tatagggatt gctcatattt tatcaatgta ttctatacaa aattatttta ggtcctatat
    25141 tccgaattta aagagcgttt gaaatgggtc taaaaatgtt tgaaactaat tgaatgtgtg
    25201 tataatagta aaaatgcagt aaatatcccg acaatttcta ttgacaattc aaacagattg
    25261 gtttattatt aatataacaa caaatgaaag cgcaaacttt cgcggtcgga aggtagtttt
    25321 atgacacgat ttgagatacg agatgatttc tatctcgatg gaaaatcatt taagatttta
    25381 tctggtgcca ttcattattt tagggttcct ccagaggatt ggtatcattc gctctataac
    25441 ttgaaggctc ttggttttaa tacggtagag acttatgttg cttggaattt acacgagcct
    25501 cgtgaaggtg agtttcattt tgaaggtgat ctggatttag agaaatttct ccaaatagcg
    25561 caggatttgg gtctctacgc aattgtgcgt ccgtctccat ttatctgtgc ggaatgggaa
    25621 ttcggtggct taccagcttg gctcttgacc aagaacatgc gaattcgctc atccgaccca
    25681 gcatatatcg aggcagttgg tcgctactat gatcagttat tgccaagact ggtgcctcgt
    25741 ttgttgaaca atggtggcaa tattctcatg atgcaggttg aaaatgagta tggttcttac
    25801 ggagaagata aggcttacct gagagcgatt cgacagctaa tggaagagtg tggcgtaacc
    25861 tgtcccctct ttacatcaga tggtccatgg cgagctactc tgaaagctgg aaccttaatt
    25921 gaagaggacc tctttgtaac aggaaacttt ggttctaagg caccttacaa cttttcgcag
    25981 atgcaggaat tctttgatga acatggtaag aaatggccac tcatgtgtat ggagttctgg
    26041 gatggttggt tcaatcgctg gaaagaaccg attatcacac gggatcctaa ggaattggca
    26101 gatgcagttc gagaggtttt ggaacaaggc tctatcaatc tttacatgtt ccacggtggt
    26161 acaaactttg gtttcatgaa tggttgctca gctcgaggaa ctttggacct gccacaagtt
    26221 acatcttatg attacgatgc ccttctggat gaagaaggaa atccaactgc taaatatctt
    26281 gcagtcaaga agatgatggc aacacatttt tcagagtatc cgcagttgga accactctac
    26341 aaagagagta tggagttgga tgctattcca ctagttgaaa aagtttcttt gtttgaaacc
    26401 ttagatagct tgtcaagtcc tgtagaaagt ctctatcctc aaaagatgga ggagctggga
    26461 caaagttatg gctacctact ttatcgaaca gaaacaaact gggatgcaga agaagaaaga
    26521 cttcgtatca ttgatggtcg agatagggcc cagctgtatg tcgatggtca gtgggttaaa
    26581 actcaatatc agacagagat tggggaagat attttttatc aaggtaaaaa gaaagggcta
    26641 tctaggttag atatcttgat agaaaatatg gggcgtgtca actatgggca taagttctta
    26701 gcggatacgc aacgtaaggg aattcggaca ggggtctgta aggatctgca tttcttacta
    26761 aactggaaac actatccact cccactagac aatcctgaga aaattgattt ttcaaaagga
    26821 tggactcaag gacaaccagc cttttacgct tatgacttta cagtcgaaga gccaaaagat
    26881 acttacctag acttgtctga gtttggtaag ggagttgcct ttgtcaatgg gcagaatcta
    26941 ggacgttttt ggaacgttgg cccaactctc tcactttata tccctcatag ctatctcaag
    27001 gaaggtgcca accgtatcat tatctttgaa acagaaggtc aatataaaga agagattcat
    27061 ttaactcgta aacctacact aaaacatata aagggggaaa acttatgaca attgtaggat
    27121 gccgtattga tggacgtttg atccacggac aagtagccaa tctttgggct ggaaaactaa
    27181 atgtttcacg cattatggtt gtagacgacg aagttgtcaa caacgatatt gaaaagagtg
    27241 gtttgaaact tgcgacacca ccaggtgtga aattgagtat tttgccagtt gagaaagctg
    27301 cagccaatat tcttgctggt aaatacgata gccaacgtct ctttatcgtg gctcgtaaac
    27361 cagaccgctt ccttggtttg gtagaagcag gtgtaccact tgaaaccctt aatgttggga
    27421 atatgtctca aacaccagaa actcgttcta ttacacgttc tatcaacgta gtagacaagg
    27481 atgtggaaga cttccacaaa ctggcagaaa aaggtgttaa acttactgct cagatggttc
    27541 caaatgatcc aatttcagac tttttgagct tattaaaata ggaaaaaaat ttttaggagg
    27601 tcattgttat gatacaatgg tggcaaattt tacttctcac tttgtactca gcttatcaaa
    27661 tctgtgatga gttgacgatc gtttcatctg caggttcccc tgtatttgct ggtttcatta
    27721 ctggtttaat catgggagat gtgactactg gtttacttat cggtggtaac ttgcaactgt
    27781 tcgttcttgg ggttggtacc ttcggtggtg cttctcgtat cgacgcaact tctggtgcgg
    27841 ttcttgcgac agccttctct gtttcacaag gaattgatgc accgcttgcc attactacaa
    27901 tcgctgtacc agtagcagct ctcttgactt acttcgacgt tcttggtcgt atgactacta
    27961 ccttcttcgc tcaccgtgtg gatgctgcaa tcgaacgctt tgactataaa ggtattgaac
    28021 gcaactactt gcttggtgcg attccgtggg ctctatctcg tgcccttcca gtcttctttg
    28081 cccttgcttt tggtggtgcc tttgtacaat cagtagtaga cttcgttgaa gcctacaaat
    28141 gggttgcaga tggcttgaca ctcgcaggac gtatgcttcc aggtcttgga tttgcaatct
    28201 tgcttcgtta ccttccagtt aaacgtaacc ttcactacct tgctatggga tttggtttga
    28261 cagctatgtt gactgttctt tactcatatg taacaggtct tggtggcgct gttgctggta
    28321 tcgtaggtac tcttcctgct gaagttgctc aaaaaattgg tttcgtgaac aacttcaaag
    28381 gtttgtctat gattggtatt tctatcgtag gtattttcct tgcagtgctt cacttcaaaa
    28441 atagccaaaa agtagctgta gcagcacctt ctacaccatc agaaagtggg gaaatcgaag
    28501 atgacgaatt ctaattacaa acttacaaaa gaagatttta atcaaatcaa caaacgtagc
    28561 ttgtttactt tccaattagg ttggaactac gaacgtatgc aagcttctgg ttacctttac
    28621 atgatcttac ctcagttgcg taaaatgtat ggtgatggaa ctcctgaatt gaaagaaatg
    28681 atgaaagttc atactcaatt cttcaatact tcgccattct tccataccat tatcgctggt
    28741 tttgaccttg ccatggaaga aaaagatggt gtaggttcaa aagacgctgt taacggtatc
    28801 aagacaggtt tgatgggacc attcgctcct cttggggata caatctttgg ttcacttgta
    28861 cctgctatca tggggtcagt cgcagcaact atggctatcg ctggccaacc ttgggggatc
    28921 ttcctttgga ttgcagttgc agtagcgtat gacatcttcc gttggaaaca gttggaattt
    28981 gcttacaaag aaggggttaa ccttatcaac aacatgcaaa gtaccttgac agctttgatt
    29041 gacgctgcat ctgtacttgg tgtcttcatg atgggtgctc ttgtagcaac agtgattaac
    29101 tttgaaattt cttacaagtt gccaatcggt gaaaagatga ttgatttcca agacatcttg
    29161 aaccaaatct tcccacgttt gcttccagca atctttactg cctttatctt ctggttgctt
    29221 ggtaaaaaag gtatgaactc tactaaagct atcggtatta ttatcgtact tgctttggct
    29281 ctttctgccc ttggtcactt tgcacttgga atgtaattcc ttatgactaa atcattaatt
    29341 ttggtgagcc atggtcgctt ctgtgaggag cttagaggta gcacagaaat gattatgggc
    29401 ccacaagaca acatttacac agtagctctt cttccagaag atggcccaga agaatttact
    29461 gctaaatttg aagctgttat tgaagggttg gatgatttcc tagtctttgc ggatcttctc
    29521 ggtgggacac cttgtaatgt ggtgagtcgc ttgatcatgg aaggtcgtga tattgacctt
    29581 tacgcaggga tgaatcttcc aatggtgatt gaatttatca atgcgagcct tacaggcgca
    29641 gatgcggact acaagagccg tgctgcagaa agtattgtga aagttaatga cctgttagcg
    29701 ggcttcgatg atgacgaaga tgaataatac tcttcgaaaa tctcttcaaa ctacgtcaac
    29761 gtcgccttgc cgtaggtata tgttactgac ttcgtcagtc ttatccggca acctcaaaac
    29821 ggtgttttga gctgacttcg tcagtcttat ccggcaacct caaagcagtg ctttgagcag
    29881 cctgcggcta gtttcctaca gattttagtt ggaactcgat tcaattcatg tgacaacgtg
    29941 aaaatcgtta gagcatttta tataaaatat acatgggaat ggagcttact cccattccca
    30001 tatttaatag aaaaagagga actcaatgct acattataca aaagaagact tgctcgaatt
    30061 gggtgcagaa atcactacgc gtgaaatcta ccaacagcct gatgtatgga gagaagcttt
    30121 tgaattttat caagcaaaac gtgaagaaat tgcagccttc ctacaagaaa tcgctgataa
    30181 acatgactat attaaggtta tcttgacagg tgctgggact tctgcttatg tgggagatac
    30241 cttgctacct tactttaagg aagtctatga cgaacgcaaa tggaatttca atgctattgc
    30301 gacaacagat atcgttgcca atccagcaac ctatttgaaa aaagatgtgg caactgtcct
    30361 tgtgtctttt gctcgtagtg ggaactcgcc tgaaagtgtg gcgactgttg atttggccaa
    30421 atccttggtg gatgagcttt atcaagtgac gattacttgt gcaacagatg gtaaattggc
    30481 tcttcaagct cacggtgatg accgtaatct cttgctcttg caaccagctg tctctaatga
    30541 tgctggattt gccatgactt ctagctttac gtctatgatg ttgacagctc tcttggtctt
    30601 tgatcctaca gaatttgctg ttaagtctga acgttttgaa gttgtatcta gtcttgcccg
    30661 taaagtttta gacaaggcag aagatgtcaa agagctcgtt gatttagact ttaaccgtgt
    30721 catctatcta ggcgctggtc ctttctttgg acttgctcat gaagctcagc tcaagatttt
    30781 ggaattaact gctggtcaag ttgcgaccat gtatgaaagc ccagttggct tccgtcacgg
    30841 tccaaaatct cttatcaacg acaatacagt tgttttggtc tttggtacaa cgacagacta
    30901 cactcgtaag tacgacttgg acttggttcg tgaagttgct ggtgaccaga ttgctcgtcg
    30961 tgttgtgctt ttgagtgatc aagcttttgg tcttgaaaat gtcaaagaag tggcccttgg
    31021 ttgtggcggt gtcttgaatg atatttaccg tgtcttccct tacatcgttt atgcccaact
    31081 ctttgcccta ttgacttcac ttaaggtaga aaataaacca gatacaccgt ctcctacagg
    31141 tacagtaaac cgtgtagtac aaggtgtcat aattcacgaa tatcaaaagt aagacagtgt
    31201 ttatgaattc ttgacaagag gatttgtaaa ttatcagata aaccatagat tgtcagtacg
    31261 ctttctatgg tttgtttgct tgagagaaat agtaaaagga gaacagaatg aaagcataca
    31321 cagagcgtgt atttggaaat gttgagggcg aggatgtctt ggcctatcga tttgagacag
    31381 acggtggcta ccaacttgag gttatgactt atggtgcgac catcttgcgc tatgtcgcac
    31441 ctgacaaggc tggaaatttt gccaatgtta tcttgggatt tgatgacttt gatagttatg
    31501 taggcaatag tcccaagcat ggagcaagtg taggtcctgt agcgggtcgt attgcaggtg
    31561 cgacctttga gctcaatggt aagacctatg accttgaggt taataatgct agcaactgta
    31621 atcacagtgg ttcaactggt tgggattcca gcttgtttga agttgaagaa gtaagcgatc
    31681 atggcttgac tctctacaca gagcgtacag atgggacagg agggttccct ggaaatctca
    31741 agatttggat cagttatcac ttggaagaaa ctggtgccta tgaaatcagc tacaaggtga
    31801 cgaccgatca ggatacgctg gtcaatccaa ccaaccacag ctatttcaac ttgtctggtg
    31861 atttcacgca gacgattgac cgtcatgtct tccaactaaa cacagagggc atttactcaa
    31921 tcgctcctga cggtgttcct gccaaaactc cagaagccaa ccgtgatgtg gtcaaacacg
    31981 tctacaatgg taccttgttg aaggatatct ttgcagaaga agatgagcaa atccagctgg
    32041 catcaggttt ggatcatcca tttgcccttc ctgcaggcca tgacaatgct ggattccttt
    32101 atgaccaaaa ttcaggtcgc ttcctgcttt tcaagacaga agctccttgc tttgtggtct
    32161 acacagcaaa ctttgtggat gaaagtgtca tcataggagg tcagccaatg ctacagcaca
    32221 atgggattgc tcttgaagcg caagctttac cagatgccat tcacagtgac cttaaaggcc
    32281 aagtcattct taaagctggt caaaccttca ccagtaagac acgttatgaa cttgttgtga
    32341 aataaaaaag ctggtcaaaa agtctttaaa attaaaataa cgcatattgt caggtgatga
    32401 aaagtttgat aatatgcgtt ttattatgaa atgatttact ttatattatc ctgaaatggt
    32461 gttatttttg agttatctgg cttgactttc ttgatggaaa ttatataata gttgtaataa
    32521 taataattac aacgagaaaa gaggaccatt tatgacctat gaatacaaga gtcacattta
    32581 tttggcagag acagctttaa atgtaaagga tttggccagt caaacagcct tttatcagca
    32641 agttattggt ttagaaatct tatctcaaac tgagacagag tccattctag gccttggtgg
    32701 aaaagtcttg gtacagctga ttcaagcaca agagagcgga gaagtgaggg aacattatgg
    32761 tctttaccat ttggccattc tcttgcccac acgcaaggct ttggctgatg tcttgaaaca
    32821 cctgacagat ttacagattc ctcttgtcgg cggtgcagac catggttaca gtgaagctat
    32881 ttacttggaa gatttggagg gaaatggcat tgaactctat cgagataagc cagtttccac
    32941 atgggatatt cgagaagatg gacgcattat cggagtgacg gaggcttttg cggcgcagga
    33001 catttatgag ttgggggaaa gagtagagcc ctttatcctg gcagaaggta cgagaatggg
    33061 gcatattcat ctttccgtca aggatagtcg aaagtccagc cagttttatc aaaaggtgtt
    33121 agggctagag gataaattca gtgtgcctag cgctagttgg attgcggctg gagattacca
    33181 tcatcattta gcagttaacg aatggggagg aaaaggtctg gcttcgcgta agcaaggctt
    33241 accaggttta gcctactatg tcatcgaagt cgcacataaa gaagaactgt taacgattgt
    33301 ccaacgagca caagaagttg acgcaccaat caaatggatg acatcgagcc aattggaaat
    33361 cacagactca gatggcatcg tgacccgtat tcgtttagca aggtaaaatt aggaatttct
    33421 aataagttat aagtattgct agtttgcttt ttgaacggtc tttggtaaca gaactgcgtg
    33481 agctggatgg gtgagaattt tgacaaagaa gctgattaga gatataatga agaaaaatcg
    33541 agcaaggaaa aagaaatgac aaattcaaag tatattactt gtttgaaacg ttcagagggc
    33601 cagttgtgtg ggattcaaaa gatgattgaa ggagatcgtg actgtgctga tattgtgacg
    33661 caactgacag cagtgagatc tagtgtagag cgcgtgattg agatgataat taccgaaaat
    33721 cttactgaat gtatcaatca gccactagat gattctgaag ctcaaaagga acgcctagaa
    33781 aaggctatcc gatacttgat taaacggaaa taaatgaatg ttttgagacg atatgtgcaa
    33841 aggtctatta actattagaa tagtttaatg tgagtcaaaa gaagttgtaa aaaatcttta
    33901 aaattaaaaa aacgcatagt atcaggtgtt gaatgtactg acccccaaaa gttagatttt
    33961 ttctgtctaa cttttggggg tcagttcata agaaccttgg taatatgcgt tttattatgt
    34021 agagacttat actcttcgaa aatctcttca aaccacatca gcttcacctt gccgtagata
    34081 tggttactga cttcgtcagt tctatccaca acctcaaaac agtgttttga gctgacttcg
    34141 tcagttccat ccacaacctt aaaacagtgt tttgagcagc ctgcggctaa cttcctagtt
    34201 tgcactttaa ttttcattga gtattacttc atcttctcat gaaattgagt ttttgcccag
    34261 ctcctcttga ttattctact tgaccgggcc aagtattcat accaccttct acgttggtaa
    34321 cggtgaggcc ttgggagctg agaaattggc aggtagatgc agagcggact cctccttgac
    34381 aaataacata gtattcatgg tcaggtttga gttctttgta gccttgctct aaggtactta
    34441 atggaagatt tttggcacct ggtgcatgtc ctgcttggaa ttcatgtgct tcacggacat
    34501 cgataagttc tagattttca ttttagtatt ttccataaaa gtcagccatg ctgatactag
    34561 tttccatatt ctactccttc tgggttagcc attttgtata gtgaataagc gccgtcaagg
    34621 ttttggacgg taaatcctgc ttgcttgagg ataggctctg cgatatagct gcgcaaacca
    34681 ctgtggcagc tgacgatgta ggcttgtttt ttgtccagtt catcagcttc ctccttgaca
    34741 ctttgtcagt ttttgataca atagtacaaa attagaggag gcaggctatg attcagaaac
    34801 atgcgattcc tattttagag tttgatgaca atcctcaggc ggttatcatg cccaatcacg
    34861 aggggctgga cttgcagttg ccaaagaagt gtgtttatgc atttttaggt gaggagattg
    34921 accgctatgc aagggaagta ggggcggatt gtgtcggcga attcgtttct gctaccaaga
    34981 cctatccagt ctatgtcatc aactacaagg gtgaggaagt ctgtctggct caggctcctg
    35041 ttggctccgc tccagcagcc cagtttatgg attggttgat tggctatggt gtggagcaga
    35101 ttatctctac tgggacctgt ggtgtcctag ctgatataga ggaaaatgcc tttctagtcc
    35161 ctgttcgcgc tttgcgagat gagggagcca gttaccacta tgtggcacct tgtcgttata
    35221 tggaaatgca gccagaggct attgctgcta ttgaggaagt tttgaaagac agagggattc
    35281 cttatgaaga agtcatgacc tggacgacag acggttttta ccgagaaacg gctgaaaagg
    35341 tggcttatcg taaggaagaa ggctgtgctg ttgtggagat ggagtgttct gctcttgcgg
    35401 cagtagctca attgcgtggg gttctctggg gtgaattgtt gttcacagca gattctctag
    35461 cggacttgga ccagtacgac agtcgtgact ggggctcgga agcttttaat aaggcgctag
    35521 aactgagttt agcaagtgtt caccaccttt agttgtacag gcaaaggatt tgttttatca
    35581 taaaatgtct agctcatact tttcaaaaat atgtttaaac gaggtcacct tcctcttgtc
    35641 ctaggcatgt tgaggttggg aaaaatcttt aaaatcagaa aaacgtatca tatcaggtga
    35701 tgaaaatttt gatactatgc gttttatgtt ggtaagattt agagtgagat gaaatgatac
    35761 tcttcgaaaa tctcttcaaa ccaggtcagc ttcaccttgc cgtatagatg ttactgactt
    35821 cgtcagttct atctgcaacc tcaaaacagt gttttgagct gacttcgtca gttctatcca
    35881 caacctcaaa acagtgtttt gagcaacctg tgactagctt tctaagcgat gccttggttc
    35941 tcattgccta taatcaaaaa gagaaatttt ctcctgaaaa gcatatagag tagctggcgt
    36001 taaaagctcc tgtcttgctt ttttgaccta tagtcacatc tatcaagtat tgttcttgcc
    36061 taagctatca ataaaaaggt ggcatttttt aggcttggtg ttagtgaatt ttgccttatc
    36121 ctatctaagt catttcgagc tttttatggt acaatggaaa catgttattc aaattatcta
    36181 aggaaaaaat agagctaggc ttatctcgtt tatcgccagc ccgtcgtatt tttttgagtt
    36241 ttgccttggt cattttacta ggctctcttc ttttgagctt gccctttgtc caagttgaaa
    36301 gctcacgagc gacttatttt gatcatcttt tcactgctgt ctctgcagtc tgtgtgacag
    36361 gtctctcaac ccttccagta gctcacacct ataatatctg gggccaaata atctgtttgc
    36421 tcttgattca gatcggtggt ctagggctca tgacttttat tggggttttc tatatccaga
    36481 gcaagcaaaa gcttagtctt cgtagccgtg caactattca ggatagtttt agttatggag
    36541 aaactcgatc tttgagaaag tttgtctatt ctatttttct cacgaccttt ttggttgaga
    36601 gcttgggagc tattttgctt agttttcgcc ttattcctca acttggctgg ggacgtggtc
    36661 tttttagttc catttttcta gcgatctcag ccttctgtaa tgccggtttt gataatttag
    36721 ggagcaccag tttatttgct tttcagaccg atttactggt caatctggtg attgcaggct
    36781 tgattattac aggcggcctt ggttttatgg tctggtttga tttggctggt catgtaggaa
    36841 gaaagaaaaa aggacgtctg cactttcata cgaagcttgt actattattg actataggtt
    36901 tgttgttatt tggaacagca actactctct ttcttgagtg gaacaatgct ggaacgattg
    36961 gcaatctccc tgttgccgat aaggttttag ttagcttttt tcaaacagtg acgatgcgaa
    37021 cagctggctt ttctacgata gattatactc aggctcatcc tgtgactctt ttgatttata
    37081 tcttacagat gtttctaggt ggggcacctg gaggaacagc tgggggactc aagattacga
    37141 cattttttgt cctcttggtc tttgcacgaa gtgagcttct aggcttgcct catgccaatg
    37201 ttgcgagacg aacgatcgcg ccgcgaacgg ttcaaaaatc ctttagtgtc tttattatct
    37261 ttttgatgag cttcttgata ggattgattc tgctagggat aacagccaaa ggcaatcctc
    37321 cctttatcca cctcgtattt gaaaccattt cagctcttag tacagttggt gtaacggcaa
    37381 atctgactcc tgaccttggg aaattggctc tcagtgttat catgccactt atgtttatgg
    37441 gacgaattgg tcccttgacc ttgtttgtta gcttggcaga ttaccatcca gaaaagaaag
    37501 atatgattca ctatatgaaa gcagatatta gtattggtta agaaaggaaa gagcatgtca
    37561 gatcgtacga ttggaatttt gggcttggga atttttggga gcagtgtcct agctgcccta
    37621 gccaagcagg atatgaatat tatcgctatt gatgaccacg cagagcgcat caatcagttt
    37681 gagccagttt tggcgcgtgg agtgattggt gacatcacag atgaagaatt attgagatca
    37741 gcagggattg atacctgcga taccgttgta gtcgcgacag gtgaaaatct ggagtcgagt
    37801 gtgcttgcgg ttatgcactg taagagtttg ggggtaccga ctgttattgc taaggtcaaa
    37861 agtcagaccg ctaagaaagt gctagaaaag attggagctg actcggttat ctcgccagag
    37921 tatgaaatgg ggcagtctct agcacagacc attcttttcc ataatagtgt tgatgtcttt
    37981 cagttggata aaaatgtgtc tatcgtggag atgaaaattc ctcagtcttg ggcaggtcaa
    38041 agtctgagta aattagacct ccgtggcaaa tacaatctga atattttggg tttccgagag
    38101 caggaaaatt ccccattgga tgttgaattt ggaccagatg acctcttgaa agcagatacc
    38161 tatattttgg cagtcatcaa caaccagtat ttggataccc tagtagcatt gaattcgtaa
    38221 agagggatga cccctctttt ttgatgccca agatggcaaa tagagacaga agccccttgt
    38281 cttctagtaa aagttcttca aaggctggac tttatggtaa aatagaaaga agtgacaaga
    38341 gagagtaata ctcaatgaaa atcaaagatc aaactaggaa actagctacg ggctgctcaa
    38401 aacagtgttt tgaagttgtg gatagaactg acgaagtcag ctcaaaacac tgttttgagg
    38461 ttgcagatag aactgacgaa gtcagctcaa aacactgttt tgaggttgca gatagaactg
    38521 acgaagtcag taacatctat acggcaaggc gacgttgacg cggtttgaag agattttcga
    38581 agagtataag aaaaaatcag tcccctaaag gagcagatta tgaagttatt gtctatcgca
    38641 atttctagct ataatgcagc agcctatctt cattactgtg tggagtcgct agtgattggt
    38701 ggtgagcaag ttgggatttt gattatcaat gacgggtctc aggatcagac tcaggaaatc
    38761 gctgagtgtt tagctagcaa gtatcctaat atcgttagag ccatctatca ggaagataaa
    38821 ggccatggcg gtgcggtcaa tcgtggcttg gcagaggctt ctgggcgcta ttttaaagta
    38881 gttgacagtg atgactgggt ggatcctcgt gcctacttga aaattcttga aaccttgcag
    38941 gaatttgaga gcaagggtca agaggtggat gtctttgtga ccaattttgt ctatgaaaag
    39001 gaaggtcagt cttgtaagaa gagtatgagt tacgattcag tcttgcctgt tcggcagatt
    39061 tttggctggg accaggtcgg aaatttctcc aaaggccagt atatcatgat gcactcgctg
    39121 atttatcgga cagatttgtt gcgtgctagc cagttctaat tgcctgaaca tactttttat
    39181 gtcgataatc tctttgtctt tacgcccctt cagcaggtca agaccatgta ctatctgcct
    39241 gtcgatttct atcgttattt gattgggcgt gagggccagt ctgtcaatga gcaagtgatg
    39301 attaagtgca ttgaccagca actcaaggtc aatcgactct tggtagacca gcttgatttg
    39361 tcccaagtga gtcatcctaa aatgcgagaa tatctgctga atcatattga aatcacgacg
    39421 gtgatttcca gtaccctgct caaccgatct gaaacagcgg agcatctggc aaaaaaacgc
    39481 caattgtgga cctatattca gcaggaaaat ccaaaagtct ttcaggctat tcgtaagacc
    39541 atgttgagcc gtttgaccaa acattctgtc ttgccagatc gcaaactgtc caatgtcgtc
    39601 tatcaaatca ccaaatctgt ttatggattt aattaatata agtgttttat aagagggatt
    39661 taagaaaaat tttaactttt tcttagtcct ttttaatttc aggagattat actagagtca
    39721 tcaaataaag aaagactcta aggagaatcc tatgaaattc aatccaaatc aaagatatac
    39781 tcgttggtct attcgccgtc tcagtgtcgg tgttgcctca gttgttgtgg ctagtggctt
    39841 ctttgtccta gttggtcagc caagttctgt acgtgccgat gtggtcaatc cgaccccagg
    39901 tcaagtctta cctgaagaga catcgggaac gaaagagggt gacttatcag aaaaaccagg
    39961 agacaccgtt ctcactcaag cgaaacctga gggcgttact ggaaatacga attcacttcc
    40021 gacacctaca gaaagaactg aagtgagcga ggaaacaaac tcttctagtc tggatacact
    40081 ttttgaaaaa gatgaagaag ctcaagaaaa tccagagcta acagatgcct taaaagaaac
    40141 tgtagataca gctgatgtgg atgggacaca agcaagtcca gcagaaacta ctcctgaaca
    40201 agtaaaaggt ggagtgaaag aaaatacaaa agacagcatc gatgttcctg ctgcctatct
    40261 tgaaaaagct gaagggaaag gtcctttcac tgccggtgta aaccaagtaa ttccttatga
    40321 actattcgct ggtgatggta tgttaactcg tctattacta aaagcttcgg ataatgctcc
    40381 ttggtctgac aatggtactg ctaaaaatcc tgctttacct cctcttgaag gattaacaaa
    40441 agggaaatac ttctatgaag tagacttaaa tggcaatact gttggtaaac aaggtcaagc
    40501 tttaattgat caacttcgcg ctaatggtac tcaaacttat aaagctactg ttaaagttta
    40561 cggaaataaa gacggtaaag ctgacttgac taatctagtt gctactaaaa atgtagacat
    40621 caacatcaat ggattagttg ctaaagaaac tgtcgaaaaa gctgttaaag ataacgttaa
    40681 agacagtatc gatgttccag cagcctacct agaaaaggcc aagggtgaag gtccattcac
    40741 agcaggtgtc aaccatgtga ttccatacga actcttcgca ggtgatggca tgttgactcg
    40801 tctcttgctc aaggcatctg acaaggcacc atggtcagat aacggtgagg ctaaaaaccc
    40861 agccctatct ccactaggcg aaaacgtgaa gaccaaaggt caatacttct atcaagtagc
    40921 cttggacgga aatgtagctg gcaaagaaaa acaagcgctc attgaccagt tccgagcaaa
    40981 tggtactcaa acttacagcg ctacagtcaa tgtctatggt aacaaagacg gtaaaccaga
    41041 cttgactaat ctagttgcta ctaaaaaagt cactattaac ataaacggtt taatttctaa
    41101 agaaacagtt caaaaagccg ttgcagacaa cgttaaggac agtatcgatg ttccagcagc
    41161 ctatttagaa aaagccaagg gtgaaggtcc attcacagca ggtgtcaacc atgtgattcc
    41221 atacgaactc ttcgcaggtg atggtatgtt aactcgtctc ttgctcaagg catctgacaa
    41281 ggcaccatgg
//
LOCUS       DAVLTT010000015        34480 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLTT010000015 DAVLTT010000000
VERSION     DAVLTT010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34480
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.015"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(65..629)
                     /locus_tag="VYN15_000821"
                     /pseudo
     CDS             complement(65..629)
                     /locus_tag="VYN15_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(705..932)
                     /locus_tag="VYN15_000822"
     CDS             complement(705..932)
                     /locus_tag="VYN15_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001815354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1452173.1"
                     /translation="MRERLLTQPLLHADETSYRVLESDSQLTYYWTFLSGKSEKQGIT
                     LYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            960..1268
                     /locus_tag="VYN15_000823"
                     /pseudo
     CDS             960..1268
                     /locus_tag="VYN15_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1423..1746)
                     /gene="tnpB"
                     /locus_tag="VYN15_000824"
     CDS             complement(1423..1746)
                     /gene="tnpB"
                     /locus_tag="VYN15_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1452174.1"
                     /translation="MTIHLSSLGQVYLVCGKTGMRQGIDSLAYLVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPKI"
     gene            complement(1727..1912)
                     /locus_tag="VYN15_000825"
     CDS             complement(1727..1912)
                     /locus_tag="VYN15_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452175.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            complement(2216..3778)
                     /gene="guaA"
                     /locus_tag="VYN15_000826"
     CDS             complement(2216..3778)
                     /gene="guaA"
                     /locus_tag="VYN15_000826"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV1452176.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3920..4618
                     /locus_tag="VYN15_000827"
     CDS             3920..4618
                     /locus_tag="VYN15_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1452177.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKYGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4661..5557)
                     /locus_tag="VYN15_000828"
     CDS             complement(4661..5557)
                     /locus_tag="VYN15_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1452178.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(5566..6501)
                     /locus_tag="VYN15_000829"
     CDS             complement(5566..6501)
                     /locus_tag="VYN15_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV1452179.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRVLLTAPELKEVMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQTFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6498..7223)
                     /locus_tag="VYN15_000830"
     CDS             complement(6498..7223)
                     /locus_tag="VYN15_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV1452180.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(7307..7942)
                     /locus_tag="VYN15_000831"
     CDS             complement(7307..7942)
                     /locus_tag="VYN15_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV1452181.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTLKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKAYLY"
     gene            complement(7944..8771)
                     /locus_tag="VYN15_000832"
     CDS             complement(7944..8771)
                     /locus_tag="VYN15_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1452182.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8793..9129)
                     /locus_tag="VYN15_000833"
                     /pseudo
     CDS             complement(8793..9129)
                     /locus_tag="VYN15_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(9130..9846)
                     /locus_tag="VYN15_000834"
     CDS             complement(9130..9846)
                     /locus_tag="VYN15_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEV1452183.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGIAPIGVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIVY"
     gene            10359..10970
                     /locus_tag="VYN15_000835"
     CDS             10359..10970
                     /locus_tag="VYN15_000835"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1452184.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11015..11743
                     /gene="rlmB"
                     /locus_tag="VYN15_000836"
     CDS             11015..11743
                     /gene="rlmB"
                     /locus_tag="VYN15_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV1452185.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(11781..12692)
                     /gene="trxB"
                     /locus_tag="VYN15_000837"
     CDS             complement(11781..12692)
                     /gene="trxB"
                     /locus_tag="VYN15_000837"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV1452186.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQVFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12758..12982)
                     /locus_tag="VYN15_000838"
     CDS             complement(12758..12982)
                     /locus_tag="VYN15_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV1452187.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13060..13803)
                     /locus_tag="VYN15_000839"
     CDS             complement(13060..13803)
                     /locus_tag="VYN15_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1452188.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMPFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFTSYKRTYI"
     gene            complement(13803..14603)
                     /locus_tag="VYN15_000840"
     CDS             complement(13803..14603)
                     /locus_tag="VYN15_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1452189.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14761..15117)
                     /locus_tag="VYN15_000841"
     CDS             complement(14761..15117)
                     /locus_tag="VYN15_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1452190.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15111..15641)
                     /locus_tag="VYN15_000842"
     CDS             complement(15111..15641)
                     /locus_tag="VYN15_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV1452191.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRSNRRRSTC"
     gene            complement(15641..16135)
                     /locus_tag="VYN15_000843"
     CDS             complement(15641..16135)
                     /locus_tag="VYN15_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1452192.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16270..16716
                     /locus_tag="VYN15_000844"
     CDS             16270..16716
                     /locus_tag="VYN15_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV1452193.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTIKLYHQTLDLIDHTQEEVIQ"
     gene            16713..17360
                     /locus_tag="VYN15_000845"
     CDS             16713..17360
                     /locus_tag="VYN15_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV1452194.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(17381..17962)
                     /gene="pdxT"
                     /locus_tag="VYN15_000846"
     CDS             complement(17381..17962)
                     /gene="pdxT"
                     /locus_tag="VYN15_000846"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV1452195.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(17963..18838)
                     /gene="pdxS"
                     /locus_tag="VYN15_000847"
     CDS             complement(17963..18838)
                     /gene="pdxS"
                     /locus_tag="VYN15_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV1452196.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(18990..20369)
                     /locus_tag="VYN15_000848"
     CDS             complement(18990..20369)
                     /locus_tag="VYN15_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1452197.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20663..21586
                     /locus_tag="VYN15_000849"
     CDS             20663..21586
                     /locus_tag="VYN15_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV1452198.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21646..22251
                     /locus_tag="VYN15_000850"
     CDS             21646..22251
                     /locus_tag="VYN15_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1452199.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22269..23513
                     /locus_tag="VYN15_000851"
     CDS             22269..23513
                     /locus_tag="VYN15_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1452200.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNTYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGDHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23736..23993)
                     /locus_tag="VYN15_000852"
     CDS             complement(23736..23993)
                     /locus_tag="VYN15_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV1452201.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24035..26071)
                     /locus_tag="VYN15_000853"
     CDS             complement(24035..26071)
                     /locus_tag="VYN15_000853"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV1452202.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26331..27248)
                     /gene="glyQ"
                     /locus_tag="VYN15_000854"
     CDS             complement(26331..27248)
                     /gene="glyQ"
                     /locus_tag="VYN15_000854"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV1452203.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(27267..28028)
                     /locus_tag="VYN15_000855"
     CDS             complement(27267..28028)
                     /locus_tag="VYN15_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1452204.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(28301..29143)
                     /locus_tag="VYN15_000856"
     CDS             complement(28301..29143)
                     /locus_tag="VYN15_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV1452205.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYHAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29257..30648)
                     /locus_tag="VYN15_000857"
     CDS             complement(29257..30648)
                     /locus_tag="VYN15_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV1452206.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVLENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(30883..31260)
                     /locus_tag="VYN15_000858"
                     /pseudo
     CDS             complement(30883..31260)
                     /locus_tag="VYN15_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            31475..32452
                     /locus_tag="VYN15_000859"
     CDS             31475..32452
                     /locus_tag="VYN15_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1452207.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQIPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            32449..33531
                     /locus_tag="VYN15_000860"
     CDS             32449..33531
                     /locus_tag="VYN15_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1452208.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     ILRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(33595..34480)
                     /locus_tag="VYN15_000861"
                     /pseudo
     CDS             complement(33595..34480)
                     /locus_tag="VYN15_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        10253 a         7699 c         6209 g        10319 t
ORIGIN      
        1 aggaaaattg atttatagaa atgttttagc agtcgatgcg tactgttata gattcaacgc
       61 actataattg atgacgttta gctgtttcca acaaactcat aataatagct cttgctttag
      121 ctccttcaaa actttgagaa aataaccacc ctcgcttttt taaactgagc ttaggctaaa
      181 agagtccact ggactctttt actccgtccc ataaccaatg atttaatggc gcattcagct
      241 agattattgg aaaggaccag atgtccgtct ttcaaaatag tcttaaaggt ttctttatac
      301 ttgaggctat acttgaggct gtattcaatt gcccttccta gttttgaacc cgataaaact
      361 gactgacgcc ggcaccaagc aaagaagtct tccattaggg gctggagatg ttcttgacgt
      421 ttctgtagtc gttcatcagc tggcaaagcc tcccagtctc tttccaagga aaataactga
      481 tcacaataag ctaaaccttt agctcctaag gatgatttat ctgcttgctt gggggtcgct
      541 tcaaaaaatt tccttctcac atgcgcccaa catccaacaa gtgcagcttc ttccagttga
      601 cgataagctt ctagcggttc gcagtttacc aagcttagcg tcgccttgct cctaaacctt
      661 ggactgctat cgcataggca gaactagagg actaaagtcc taagttactg ccgcaacata
      721 tcacaatgaa catagccaga ataatctcct aggaattctt gtactactga accacttcga
      781 cactgatcat ggtggtaaag cgtaatccct tgtttctctg atttacctga caaaaaagtc
      841 caatagtaag tcagctgact atcactttct aagacccgat aagaggtttc atctgcatga
      901 agtaagggct gagtcaatag tctctctcgc aagaggttat aaagaggctt taggaatagg
      961 agctttcaca agcttatcca gatgattatc ttttactcgt tatggacaat gctatatggc
     1021 ataaatcaag tatcttaaag attccgacta atattggttt tacctttatt cctccataca
     1081 caccagagat gaaccccatt gaacaagtgt ggaaagagat tcgtaaacgt ggatttaaga
     1141 ataaagcctt tcgaactttg gaagatgtca tgaatcaact tcaagatgtt atacaaggac
     1201 tggagaagga ggtgataaag tccatcgtta atcggagatg gactagaatg ctttttgaaa
     1261 gcagatgagt ataaaaagaa agtcctcatt tcaatagaaa tcacgacttt ctgatggatt
     1321 tatagtaaaa tgaaataaga acaggacaaa tcgatcagga cagtcaaatc gatttctaac
     1381 aatgttttag aagtaaaggt gtactattct agtttcaatc tactatattt ttggagtgat
     1441 agaaaaacct ttcatcagcc aatctacttg ttcaggtgcg agagctttga catccttttc
     1501 tgtactgggc caagtcagtc tgccgttctc aaagcgttta tataatagcc aaaatccttg
     1561 accatcccag taaaggactt taaagcggtc tttacgtcca ccacaaaaga gaaaaacttg
     1621 acctgagaaa gaatccaatt caaagtgggt tttaaccaga taagccagtg aatcgattcc
     1681 ttgtctcata cccgttttcc cacatacgag atagacctgc cctaggctag atagatgaat
     1741 tgtcatagag caacacctta tccaaaagct gttctatcat ttcgagattg agagattgaa
     1801 aaaaacttac ttcaagcttg ccaatacgaa ttttaagcag aatatcattt ctctttttag
     1861 aatcaaaacg acgagattgt ggaatctcta caggaacaat aggttgtggc attaaaatat
     1921 cctccaatag ttttacttta ctaatagtat acaggaggag ctccatgaat gatagatacc
     1981 ttgttatgac gcgcttacca tattagaaag ttggctctct aattaaatta attctcatta
     2041 tatatatcaa aagaccgcag cttgaaaact acggtctaat tttttgtcca aatgtaaacc
     2101 acttggaact attattcaat ttattctttt tagcaaatgt tcccgtttta atcccagtta
     2161 cagtttttaa tcctctgtaa ccgttgattt tacaaagctt ttaatttttt tgcgattatt
     2221 cccactcaac tgttgcaggt ggtttacttg taatatcgta gacgatacgg ttaacatgat
     2281 ccacttcatt tacgatacgt actgagattt tttgaagtac ttcccatgga attttggcaa
     2341 aatcagcagt cataccatcg atagaagtga tagcacggat tgcaatcgtg tagtcatacg
     2401 tacgaccgtc acccataaca ccgactgagc gaacgcctgt gttaacagtg aagtattgcc
     2461 aaatatcgcg gtcaagtcca gctttagcga tttcttcacg aagaatagcg tctgattcac
     2521 gaacggtttc aagtttctct tcagtgattt cacccatgac acggatagca agtcctggtc
     2581 ctgggaatgg ttggcgccat acgatgtggt ctggcatacc aagctctgta ccaagagcac
     2641 gaacttcatc cttgtaaaga gtattgagtg gttcaatcaa ttcaaactgc atatcttctg
     2701 gaagaccacc cacgttgtgg tgtgacttga tagtttgagc tgtatccgta ccagactcga
     2761 taacatctgt atataaagta ccttgagcaa ggaatttcac atctttgagc ttgcttgctt
     2821 cgtcatcgaa tacatagaca aactcgttac cgatgatttt acgtttttgt tcaggatcag
     2881 aaacgccagc aagtttgtca aggaaacgtt tagcagcgtc tgctttgacg atattcaaac
     2941 caaacttacc accgagcatg tccataactt gatcagcttc gcctttacga agaagaccgt
     3001 ggtctacgaa gatacagatc aattgatcgc caatcgcttt ttggagaaga accccaacga
     3061 cagatgagtc aacaccacct gatagaccaa gaaggacacg tttatcaccg acggtttcac
     3121 gaattttttt gatctgcata tcaatgaaat tatccattga ccagtcacct ttagccttac
     3181 aaatgttaag ggcaaagtta cgaaggatat catttccgta tacagaatga cgaacttctg
     3241 ggtggaattg gataccgtaa atgtgtttat ctgggttttc gatggctgcg tatgggcagt
     3301 cagctgatgt acctgtacga acaaagtcag caggaatctc agtaaccgca tcaccatggc
     3361 tcatcaaaac agtctgttca tcaggtgttg attcaaaaag cgctgatggt gtgtgagtta
     3421 gggttgattg accgtattca cgatttccag catcacctgc aggaacaact tttcctccaa
     3481 gtttatgggt caataactgc ataccataac agattcccaa aattggaatt cctagttcga
     3541 agatttctgg gtcaatgtca aatgaaccat cttcatatac agaatttgga ccacctgata
     3601 gaataattcc tacaggattg acttcacgaa cttcagcagc tgaaatttta tggcttttta
     3661 gttctgaaaa aacaccaatc tcacggatac ggcgtgaaat cagctggttg tactggctac
     3721 catagtccaa tacgatgatt ttttctacat cttgcaaatc agttgaaatg ttgctcatct
     3781 ttttcctttc tcaaaagaaa tatcttttct caatattcta tcacaaataa gggcgaatta
     3841 ccaactaaac aaggcgaagt ttgacttttt ctagtttatt ggggtacaat agagaaaaga
     3901 tagaaatgaa gtgaaaaata tgctacctgc ttatatgaaa atccatgatc agataaaaaa
     3961 ggatattgac gagcaccgtt gggctattgg tgagaggctt cccagtgaaa gagatttagc
     4021 tgagcagttt gcggtcagtc gcatgaccct ccgccaagcc gtatctctat tagtcgaaga
     4081 aggcgtctta gagcgccgtg taggaagcgg cacctttgtt tccagtactc gagtacaaga
     4141 aaagatgcga gggacaacca gttttactga aattgtcaaa tcccaaggta aagttccctc
     4201 tagccagctc atttcctaca aaaaaaccat tcccaatgag caagaagttg ccaagctagg
     4261 aatttttcca acggacaata ttatccgaat ggagcgggtc cgctatgccg accaagttcc
     4321 cctagtttat gaagttgctt ctattcctga aaaattcatt aaggacttta aaaaagaaga
     4381 aatcaccagt catttcttcc aaaccttgca aaaatatggc tatcgtatcg gcaaatctca
     4441 acagaccatc tatgctcgcc ttgctaaaga aaagattgcc cactatttgg aagttgaaaa
     4501 aggacatgct attcttggat tgacccaggt ttcctaccta gaagatggta ctgcttttga
     4561 atacgtaaaa agtcaatatg taggcgaacg ctttgaattt tatcttgaaa ataattagat
     4621 taccacgcaa aaactctctg tcacagacaa agagtctttt ttatttttct aagaataaat
     4681 ctttcaaaga aatcaaagtt acagcaaaca atatcattgc cataccaata aaatcaatgg
     4741 gataaaattg ttcattcatt attaagaagg caaagaaaac cgccgatatt ggctcaattg
     4801 aagccaacaa gcttgacttg accggtccta tcagactggc tcctttaagg aaagctgtat
     4861 aggcaaagac agtcccgata aggataatgc ctgcaaacgc aaggagaaaa tcaagactag
     4921 tcgggatatc ggcctgtaga acccctgtaa aaggaagggc gaccaaacct gctatgacca
     4981 ttcccacacc aatgaccaag ctgctccccc actttttaat caaggctatg ggtaaaatga
     5041 tatacagagc ataagtcaag gcagaaaaga gaccccagaa caggccagca ggtgtcatgg
     5101 ataactggtc caactgccca tgtgttgcga tcaggaaggt tcctccgatg gcgaatatga
     5161 tggaaactat ctctcccagt gtcggtgcca ccctatcctt gatacagcta taaattaaaa
     5221 ttccgacagg acaaacatac tgaagcaccg tcgctgttcc cgcattggtc tcctgaatag
     5281 cagacagata ggcgaattgg ttgagaaaaa gaccaatcag agcaaaaata agaagagaca
     5341 gcaaactctt tctatccttt aaaaagacca gtattttatc ctttgcagta gcataagcca
     5401 agagcatgag aattccacca gcgattaaaa gacgcaagtt ggttaagacc agagccgaaa
     5461 ttccgtgtgc catcaggtat tggccactcg ttcctgacaa cccccaagca ataccagcca
     5521 caactgttag taaagtccct tttaaactat ttgacatgtc tctccttact cttctttgcg
     5581 aatcaagttc atcacttgat tgcggtctaa tatccattga gctctctcgt ccttttcata
     5641 ggtacgattc gataggaaaa tagtggcttc ttgcttctga cgattccaca tgataaaggt
     5701 acctgtatag cccgtatggt ctagccaatc tccttccaaa ttccatgcta aagaacgttc
     5761 cttgtcatcc aaaggagaaa aattttgatt taagtctctt gcaaaatcat ctgctaaata
     5821 gtgttctaaa aaggtttgta aatcctttat agtcgaaaat aaaccagcac tcccagcatg
     5881 tctacccagg agacgagcct tgggatcatg cactatgcct gcctctacac ctctaactgt
     5941 tggaacagca agctcaactg gcccaaactt agtttccgtc attccccaag gtttccagac
     6001 ttgatccttt aaaatcacat ccaaatcttg attaaaaatt ctttccaaaa taaagcccaa
     6061 cagcaaaaaa tggacatccg aataaagaaa ggctggctga cttcgtctgt tgagatgaaa
     6121 catcacttcc tttaattcag gggctgttaa aagaacacga ttaggaataa aaggatcaag
     6181 gtctgttgca tgagtcaaga gctggcgaat agtgatgtct ggataatcac tctcaggtaa
     6241 aaaatctatt accagtctat caatatctaa ttgacctatt tcccacaaga aggtacaaac
     6301 tgtgccaacc ccaacaacct tgctgacact agctagatca taaactagtc ctgcctcagt
     6361 ctgcaagcca tgctctgggt cactctggcc taaatagaac tctgtccatt gattgtcctt
     6421 aaaatacgca aaagaggctc cgggataaat tcctgcctcg atttgttctt ctattttttt
     6481 aataatcttg gtccacttca tacttcttca aaccacaatt caacattatt tctatcttta
     6541 caaaggaaga atttttcaga cttaggaata aaatattcag tagactcaaa cttctggcga
     6601 agacttgcta tgtctaattc attgaccaag aacttgagca tagataagtc ccaggtaacc
     6661 gtattgtcca cagtcaaatc ctgcccctga gctggaataa aatcaaggga tgccccaatt
     6721 tcagatgatt ccaagaaact ttcgatatca gttgggagat gtaattccat agaaatctca
     6781 aatttactta aagaaattga tgccaaatct gtttgaaatt caggcttttc tcctacttct
     6841 actagacttg ctctgtcatc ttccgcatga atcaaaatca aatcatcttc tggtgagaaa
     6901 atttcaaaag cgtagccatt ttgaccttta tataatcgat gaatcgaatc tgttttagat
     6961 aagattcctt caatttctaa gggattttcc accttgacaa tcaatctagc tagttttttt
     7021 cttccctcta ccttacgagt acgcatactg ggagcttctt ctaaaaccag cttttcaaga
     7081 cccgtttggt cacctagtga cagaaaggcc gattcttcta acaaggcctt cattccaagg
     7141 gtttcaatat aaaatgtttc atttagtttt ctattattag cttttaaagt aggaataatc
     7201 cgtacaatct gatttacatt cataaattcc tccgtcactt tttattttaa aggattttag
     7261 aattttttac aagatattat gctcaaattt aacattattt agctatttag taaagatagg
     7321 ctttcaagga ttttgacaaa gcctgataac cagcaatact gaggtgcagt ccatcagttg
     7381 tatattcttt tttgagttgg cctgcttggt ctgtcaaaca atcaaatact ggcacaaatt
     7441 ccacctgcat ataggcagat gcaagctctt gataggcttg attccagttc tgaatttttt
     7501 cattcgagcg gatatagact gcctgctggt actcctctcc ctcattgaca ggcaaaatgg
     7561 aaagcaattt aatctctgtc aatggataat cgcgagcaac ggattgaatg atagcttcga
     7621 gattattgag agcctcattc acaggaacat cctttccgat atcatttgtc ccaatcagaa
     7681 gaaaaatttt atctactgct ccaccatata gatgagcatc aaggttctct agtaacagtc
     7741 ctgtctgata gccacgaatt cctcgattga caatcgtctt taaagttcca aatagctcct
     7801 gtagaggata atactcgaca atggaatccc caataaaaag aatgtttggt tctacaacag
     7861 aaatgtgatt taggtgacga tatttggttt gaattttttc ttgttccttt aggagccaat
     7921 tttctaataa ctgtactgcc acttcattct cctttttcta accagttttc caagacttga
     7981 taaactcctc cttggctgtt ggctggtgct agagcagtcg ccacagcttt ggctttctca
     8041 tcagcatttt ccatcgcata ggcaattcca gccatttcaa gcatttcaac atcattttca
     8101 ctatcaccaa aagccatgat ttcttgggat ttcaagtccc agcgcttgag taattcctcc
     8161 aagccccatg ctttatgaat cccagcttgg aggatatcaa tgcaaccata gccactggat
     8221 acagctcgga cacggccatc aaagagagca ttgatttctt ccaaaaccga actcaaacgt
     8281 tcctcaccaa caaccatgct catcttgagc acaccaccaa agagatcaga tgttaattca
     8341 tccacaaatt gcatccgttg gtagaatttt tcaatcattt ctggagtcat aaaactttca
     8401 agatctgtaa aaatcgtacc ttccttgaca aaatcaccct tcatccccgt tacaacaaac
     8461 tggtcctgac acgctcggcc cttgaaatga gccaaagcct tgttgacaat ggcgtcatcc
     8521 catgtctgag cctgaatcaa ttcattgttt tcaaaaatac gagcgccatt agcaacaacc
     8581 agaaccactc gatccaccaa gggactcagt agttgtctca tgcggtgaat ttcattgccc
     8641 gtcgcaatga caaaacgaat gcccctttga tccaactgat ctaaaatctt ttccaatcgt
     8701 gggagatcaa gctgacctct agcatccagc aaggtcccat ccatatctgt cgcaattacc
     8761 ttaatcatca tttactttcc tctggattca agctaatacc acttcaatcc cacatgttca
     8821 ttcatttctt tataggctgt atcaattcgt tccttagtcg cttcatctaa ctggtcacga
     8881 tgactgccac ccctctataa aatcttccaa aatataagtt tgataatgat acaagggata
     8941 tccttctggt gaaaaggttc cctttggtgt tcgattgacc caagtaggat gagctttagc
     9001 tgttccgata gttgtttttc catccttctt cttgatggtg acatccatga gaacaccacg
     9061 ttcagtccac ttagcattct cttcatctcc catagattca attcgttgat tggaaatgaa
     9121 gttccccatt taatagacaa tgagcttctt atctccatct ttttccaccg tttcagatgg
     9181 ttcaacaacg tgaggatgcc ctccaaagat aatatccgct ccccaatcga tcatcttgtg
     9241 ataaagagct ttttgttctt cagttggttc caatcgatac tcaacaccca tctgaggcat
     9301 gataatggtg atatctgctt ccttctctgc ccgttcaact tcagccttta tcttatcttc
     9361 gtttaaatct gaaagataac gattatagtc ttcctgagaa atatactgct caattccatt
     9421 gaaaccatag gaataggcta acaatgcaac cttgatagca ttcacttcct taatgaccag
     9481 cggagcctga tcacgtggtt cgtgcgtata aactccgatt ggagcgattc cagctttctc
     9541 aataatatcg gccattgaaa taactccctc aatttgcgaa tccaaaatat gattatgagc
     9601 taaatccagc acatgataac ctgcctcctt aatagcatcc ataacttcaa caggagcatt
     9661 aaagagaaga taacccgcta aataatgatc cttattaatg gttccttcaa aatcaccaat
     9721 agctaaatct gcttgcttga gccaaggagt cacatactca aaattttcat gaaagtcata
     9781 ggtaccgtct tcttttttag ctgaaaagaa aagtccatcg tggtagagca aatccccgtg
     9841 ggccataatt ctggcagttt tttcctcttc ctactcctga gacttttgct tagtcccctc
     9901 ttgagaaata gtatctcgtt tttgactagt caagggattc cttggaagct ttcaaacaac
     9961 aagaccaagc ccattgataa accaactgct agcaagagta tcgccacaaa tcccttattg
    10021 ctccacttgc gataactcct aaaaagttta ccaagccctt cataaaacga aaagctaaac
    10081 caccctgatt tcgattttgt cttctttgta tcttcgttct ccctactttc ttatgcaagc
    10141 cttttctttt tattatatca cagataagta tttctttcac aattgaattg aacttcctat
    10201 ctattttcta taaatcctaa atgccataat gctttcaatt cttgtcattt tgtgatatca
    10261 tgtagaggaa atgaactaat ccacagtggc ttattccaag tataccactt gggctttggc
    10321 agtagctaac tgcactaaac ataatataag gagagaaaat gtctgcaata gaacgtatta
    10381 caaaagctgc tcacttaatt gatatgaacg atattatccg tgaagggaat cctactctac
    10441 gcacggttgc tgaggaagtc actttccccc tatctgacca ggaaatcatc ctaggcgaaa
    10501 agatgatgca attccttaaa cattcccaag atcctgtcat ggctgaaaaa atgggactcc
    10561 gcggtggtgt tggactggct gctccccagt tagatatctc aaaacgcatt atcgctgttt
    10621 tggtacctaa tattgttgaa gaaggcgaaa ctccacagga agcctacgat ttggaagcca
    10681 ttatgtacaa tccaaaaatc gtctctcact ctgttcaaga tgctgctctt ggcgaaggag
    10741 aaggttgcct gtctgttgac cgtaacgtgc ctggctatgt tgttcgccat gcccgcgtta
    10801 ctgttgacta ctttgacaaa gatggagaaa aacaccgtat caaactcaaa ggctacaact
    10861 ccattgttgt tcagcatgaa attgaccaca ttaacggtat catgttttac gatcgcatca
    10921 atgaaaaaga cccatttgca gttaaagatg gtttactgat tcttgaataa agaaaatccc
    10981 gttgcaagac ggggttttgt gttataatag aggcatgaaa acaaatgata ttgtctatgg
    11041 tgtccacgcc gttaccgaag ccctccttgc aaatacagga aacaaactct acctccaaga
    11101 agatctccga ggtaagaatg ttgagaaagt caaggaacta gctacagaaa agaaggtgtc
    11161 catttcttgg acatcaaaaa aatctctctc tgagatgact gaaggtgctg ttcatcaagg
    11221 ttttgttcta cgagtgtctg aatttgccta tagcgagcta gattacatcc ttgcaaaaac
    11281 acgccaagaa gaaaatccac ttctattgat tctagatggt ctaactgatc cccataatct
    11341 gggttctatc ttgcgaacag ccgatgcgac caatgtttca ggtgtcatca ttcccaagca
    11401 ccgtgctgtc ggagtaactc ctgtcgttgc caaaacagcc acaggtgcta ttgaacacgt
    11461 tccaattgcc cgagtgacaa acctcagtca aaccttagat aaactcaagg atgaaggctt
    11521 ctggaccttt ggaacggata tgaacggtac tccttgccac aagtggaata caaaagggaa
    11581 aatcgccctc atcattggaa atgaaggaaa aggtatctct agcaacatca aaaaacaagt
    11641 cgatgagatg attaccattc cgatgaatgg acatgttcaa agccttaatg ccagtgttgc
    11701 tgcggccatt ctcatgtacg aagttttccg aaatagacta taaaaagttt ccagtcatct
    11761 gattggaaac ttttttataa ttaactatgt tctgtaatga atttataggc ttcttgacca
    11821 gcgatagctc catctccaac cgctgttgtt acttggcgaa ggtctttcaa gcgaacatct
    11881 ccaactgcaa agataccgtc gactgcagtc ttcatgtggc tatctgtcac aatccagcct
    11941 gcctgatctt ggatattcaa ttctttaaca aaatcgctaa gagggtccaa tccaacatag
    12001 ataaagacac caccgaagac ttgttctgtc acttgacctg ttttcacatt ttcaaatacg
    12061 actgattcta ctcggttttc acccttgatt tcccttacta cagaatccca gataaagctg
    12121 attttttcat tcgcaaaggc gcgatcttgt aaaacctttt gggcacgaag ttggtcacga
    12181 cggtgaacaa tggtaacagt cttagcaaaa cgagtcaaga agagggcttc ttcaacagct
    12241 gaatctccac caccaactac caataaatct tggtcacgga agaaagcacc atcacacaca
    12301 gcacagtaag aaacaccacg actgttcagt tcttcttctc caggtactcc caaaggacgg
    12361 tgtttagaac cagttgctac gataactgta cgtgtttcat atgtttggtc atcagtcatc
    12421 actttcttaa aatcaccatg gtcttcgaca ttttcaacat aaccataaat gtgctcaaca
    12481 ccaagatttt caagtggttc aaacatcttt tcagccaatt caggtccact aatattagcg
    12541 tatcctgggt aattttcgat atcagatgta ttattcatct gaccacctgg cagaccacct
    12601 tcaatcaaag ctacttttag attgcttcga gcagcataca aggccgcagt catccctgca
    12661 ggtccagcac cgataataat agtatcgtac atatagattc cttctttctt gttgtaacta
    12721 tctttattct aactctttct tgtcaatcac gcaaggatta tgccttgaaa acaagaatta
    12781 aactcataac cgcaaaggat aatactggga caaccaagac tccaatcata atcatatcat
    12841 agagatgggc ttggcgagcc ttggctgtct tatcaactcc cgacatggct ctcagaccaa
    12901 tccaaatccc taaaaaaatc agaacaagga tggtggtcaa gatcaaactc tcgaaatata
    12961 aagaaaatag ttgcagtagc atgatttctc tcatttctat cttttttaaa gagtaaactc
    13021 agctagtcca actaactgag ttttccttta tctattatat caaatataag tccgtttgta
    13081 actagtgaag aattcttttg tccgctcttc tttaggggtg tggataatct catccggagt
    13141 tccagactcg atgattttcc ccttatctaa gaagagaatt ttatccgcaa cttgggctac
    13201 aaagggcatg tcatgactga ccaaaatcat ggtctgacct gacttagcag catctgcaat
    13261 agacttttct acttcaccga ccaattctgg gtcaagggct gaagttggtt cgtctaagag
    13321 caaaacatct ggtttcatag caagcgcacg cgctagggca acccgttgct tctgtccacc
    13381 tgataaatgg cgaggataat ggttttcacg gtccgaaagc ccaaccttag ccaactcttc
    13441 cttggcaatc ttagtcgctt cttggtcaga taatttcttg acaacaacca agccttcttt
    13501 cacattatca agtgctgttc ggcgttcaaa taaattaaac tgttggaaaa ccatagacaa
    13561 cttacggcgt agggcaagga tttcttcttg agtgatttta gaaaaatcaa ctgaaaaacc
    13621 atcaatctga atagagccac tgtcaggtgt ttcaagataa ttgagactgc gaagaaaggt
    13681 tgattttcca gctcctgaag aaccaatcaa ggctacaact tccccttttt gaatatccaa
    13741 gttcagatga tccaagacag tctgtcctga aaaggatttg cttaaattcg aaatcttaat
    13801 cattaacgaa ggtctccttt cacatctgtt tgcactgtat caggtgcaga aatagccatt
    13861 tttctctcga tgaaacgacc gaggctttca attccgatat tgactaccca ataaacaagg
    13921 gcaacggaga tgaagcgttc aaaatagcga taatcagctc cacctagaat ctgagcttgg
    13981 gcaaagactt ccacaacacc cgcactaaaa gctagagatg ttcccttggt caaaccgatg
    14041 agggaattaa tcaaggttgg agtagctacc accgctgcat taggaataat cactcgtcga
    14101 taaacttgcg ctcgggtcat acccagactg cgtgccgcct caatctcacc aggattaact
    14161 gagagaatgg ctgcacgaat ggtttcacta gcataagctg cctcattaaa ggcaaaggcg
    14221 acaatcgcaa aagctgcagc tggaatcgca ttgatattga gaccagttcc ccattgctga
    14281 ttgagggctt tcaaagccaa aggaattccg tagtaggtca acatgagttg caccaaaatc
    14341 ggtgtccctt ttaagaaact aacaaagaag gcctgcaagg gatataaaat cttgacacga
    14401 ttgatcttca caatggcaaa aagaagcgcc aaaaccaagc caaaaagggc accaccaatt
    14461 gtcaacataa ttgttgttgg aagttgttgg acaattctag ggattccatc aaagaccgaa
    14521 cgtaggctaa acagcttgcc atccggaatc aattgcatca agttttggta ccaatctgat
    14581 gctaaaatcg ttgtaacatt cataaaaaca tcctcttctg ataatgattc attctaccat
    14641 gcttctgccg tcaatgaaat tatttgctac ggtcagatac agactttgtc tacctactag
    14701 tttatcatac tttgaaacag ggaagttata tattttatct atcaaagaga tagataaaaa
    14761 ctatttcagt cccagttctt cataagattt tcgataaccg atttgcttaa cagttccatt
    14821 ttctactaaa atgggccgtt ttaacaacat accgtcactt gctagcaact cagccgcttc
    14881 ttggtttgac aaacttccta ccttatcttt tagccctaat tcacggtatt tgataccact
    14941 ggtgttgaaa aattgcttca attcaaatcc tgaggtttct agccaattca aaatgacttc
    15001 ttggctaggt gtttcttcca cgatatggac ggctttatag tccacaccta attgatttaa
    15061 ttcttgtttt gcttttttac aagttgaaca tttggggtat tcgataaatt ctaacatgtg
    15121 cttctccttc tattgcttct atctttaaaa tctactcctt catgctccaa gagccaagct
    15181 ttcttttcca ctcctgcagc ataacctgtc agacgcttgc ctgctcccaa cacacgatga
    15241 caaggtacta ggatagacca aggattgcgt cccactgctc caccaattgc ttgagcagaa
    15301 gccacttgca ggtcttgagc aatttgtcca taggttactg tctgaccata aggaatgccc
    15361 tgtaaatagt cccaaactct cttttcaaaa ttcgttccga ttggcgccaa gagcaagttg
    15421 gataaatcct gaggcttgcc tttaaagtaa tcatctaagc aagcaataac tgggtctaaa
    15481 ataggatgac taacaacttc ttctatcgtt tcatctccta gtcccctctc aaaatgcttc
    15541 tgctcctgaa cccaaattcc atacaaataa tggtcatcag ctacaagtga tagaatacca
    15601 attggtgagg agtagagtat ttttacatac ttcttttgca ttatttcttt aatttttgat
    15661 aggccaagcg ttcgccatct actggcacct taccaacttg tttaaaacca agtttttcaa
    15721 aaatatgttg cataaccttg ttttcagcat gcgtatctga gcgaaaatca agataatcaa
    15781 aaccttcaat caagccctct aagaaggttt gagcaactcc ttttccctgc acatctgctg
    15841 ccacagcaat acggtgaaag actagatact ctgactctcc agcttgccag tttccctcat
    15901 aaatagcttc ataggcctcc tctggactct tggtcacagc agcataggct agcagttctc
    15961 cctcttccaa ggctacgtag gcttgccctg agatgatatc atcgataata acatctgcat
    16021 ttggatagcc attttgccac tggtcactac cagcatctgc taaacatttt ttggcatcct
    16081 ccatcacctg catgatggca tctacttcat ttggaaaagc taaacgaatt tccatctttt
    16141 ttcctcattt ctgactagtt tctcccatca tagcataatt taagtatttc tacaagcagt
    16201 taaaacttga ctttgtgttt ttgttatttt ataatctagt tatcaaaact atataaaaag
    16261 gagttgaaaa tgaaaactac cttttcctac ccaaaatggg cagaaattcc aaacattgac
    16321 ctctatctgg accaggtttt gctctatgtc aatcaggtct gcgcccctat ctctcctaat
    16381 aaagacaagg gcctaacagc atctatggtc aacaattatg tgaaaaatgg ttacctgaca
    16441 aagcctgaca aaaaaaaata ccaacgccaa cagattgccc gtttgattgc tatcacaacc
    16501 ctcaagtctg tattttctat tcaagaaata gcccagacac ttaatactct acaaactcaa
    16561 gcaagttcag accaactcta cgatgctttt gtggactaca tgaaccaagg aattgaccca
    16621 gctaacccta ttatccaaac cagctgccaa accattaaac tctatcatca aactctagac
    16681 ttaatcgatc atactcaaga ggaggtaatc caatgaacac tagtcttaaa ctcagcaaac
    16741 aactcagttt tggagaggag attgctaata gcgtgaccca tgctgtgggt gcagtcatca
    16801 tgcttatctt gctgcctatt tcatccatct atagttatga agcacacgga tttttatcct
    16861 ctatcggcgt ttccattttc gtcatcagtc tctttctcat gttcctatca tccaccattt
    16921 atcactctat ggcctatggt tcgacccaca aatatgtttt gcgaatcatt gaccattcta
    16981 tgatttacgt tgccattgcc ggctcataca cgcccgttgt cttgaccttg atgaataact
    17041 ggtttggcta tctgattatt gtcatccaat ggggaacgac catctttggt attctctata
    17101 aaatctttgc taaaaaggtc aatgagaaat ttagccttgc tctttacctg attatgggct
    17161 ggttggttct ggctatcatt cctgccatta tcagtcaaac gacacccgtt ttttggagtc
    17221 tcatggtaac tggcggactc tgttatacag ttggagctgg attttatgcc aagaaaaaac
    17281 cttatttcca catgatttgg catctcttta tcctagctgc gtccgtactc caatacatcg
    17341 ctattgttta ttacatgtaa aaaagttgag aaattcaatc tcaacttttt tctttacaca
    17401 tattgataaa gtactggtgc aagcgcacat catcagtcaa ttctggatga aaagaactta
    17461 ccaacatatt tttttcttgg gctgcaacaa tttgattgtt cactgttgct aaaatttcta
    17521 caccctcacc aacactactg ataatcggac cacggataaa ggtcattgga atcttgccaa
    17581 ctcccttaca ttctgcttcc gtgtagaaac ttcctaattg gcgcccataa gcattacgct
    17641 cgaccaccat atccatagtt cctagatgac tctctttctg agaagtgatt tccttagcca
    17701 gcaaaattaa ccccgcacag gtcccaaaca ctggtaagcc agatagaatg gcttctcgga
    17761 tgggaagtag catgttctgg tcacgtaaga gcttgcccat ggttgtagac tcaccaccag
    17821 gcaaaatcaa acccgacaag tcactctgat cttgctgaaa atcatctaga tttctgagtt
    17881 ctacactctc gacacctaat tgatctagca cttttgcatg ttctgcaaag gccccttgca
    17941 aggccaatat tccgattttc atctattttc ctcgttcagc catgagaatt tggatttcat
    18001 tttcattaat accaaccatg gcttctccta aatcttcaga gatttgagct aggatttgag
    18061 gattacggaa gttagtcaca gccttaacaa tggcactcgc tcgtttaaca ggatctcctg
    18121 acttgaaaat acctgaaccg acaaagaccc cctctgcccc taattgcatc attaacgcag
    18181 catctgctgg cgttgcaaca cctccagcag cgaaatttac aactggcaat tttccatgtt
    18241 catgaacata ttggaccaat tctacaggga cttgcaaatc cttggcagca acataaagct
    18301 cgtcctcacg taagttttga atgcggcgaa tttcctgatt catcatacgc atatgacgaa
    18361 cagcttggac tatatcccct gtccctggtt ctcctttggt acgaatcatg gaagcacctt
    18421 cagcgatacg acgcaaggct tcacccaaat ccttagcacc acagacaaaa ggaacttgga
    18481 attctttctt gtccacatgg aaacggtcat cagctggaga tagaacttca ctctcgtcga
    18541 tataatcaat ttcaatagcc tctaaaatct gagcttcaac aaaatgcccg attctgacct
    18601 tagccattac tggaatacta accgcttctt ggatttcctt aatcatcttt gggtcgctca
    18661 tgcgggaaac tcctccagct gcacgaatat cagccggaat tcgttccaag gccatcacag
    18721 ctgccgcacc agcagcttct gcgatacgag cctgttcagg attctgcaca tccataataa
    18781 caccaccctt gagcatctgt gccaaatttt tatttagttc ataacgattt tcagtcattt
    18841 gttttatcct catcatttgt attggtagct accttttcat tttaagtcag aacagaatga
    18901 agcacaagat aaaaaaacta taattgtatg gggacagatt ggctaaaaac tatctgacct
    18961 taacttaagg ccagatagct cattcatttt tatttttcag ccgtaagggc agccattgtg
    19021 atgtagttgt atggtttgtt gaagtgtggc aagaagaaga ggtctgtcaa tgccaattta
    19081 tcaattgtca catgctcttg gatagcaagt gagaacatgt ggattcccat gctaattgca
    19141 atatcatgtg aaaccatttg ggcaccaaga atttcacggc tatctttgtc aaagacaatc
    19201 ttaattgcta cttcatggtt gtcatgtttc atgaattctg gtttttgaag atcgttaaag
    19261 cctgtttcag ttgcgttgta accagcagct ttcgcttttt caagagtcaa accagttgaa
    19321 accatgtgaa gaccgtagat tgagatacca tttgaacctt gaacaccgat tccttccaat
    19381 tcatgtccac aagcattgta ggcaccaacg ataccagtgc gaacagcatt tgaagcaaga
    19441 gcgatatagc ttgtatcttt acgagcattg tcataaacag tcgcacagtc accaacagcg
    19501 taaacgcctg ggatagatgt ttcttgtttc ttgtctacaa ggaaggcacc gttgcggaag
    19561 agttcgatct taccatctgc aagggctgtg tttggacgga aaccaactgc aaggataacc
    19621 atatccacgt caaagctttc tttgtcagta atcaagcgtt caactttacc gtcaccttcg
    19681 attgctttaa cagtttgacc tagagccaag cggatgttgt gatcttccaa gttcttcgcc
    19741 atcatttgtg tgaagtcttt gtcatagtaa ccgttcaaga cagtatcaac gatatcaaca
    19801 aggacaactt cttttccaag acgttcaaag gcttcagcaa gttcaacacc gatgtaacca
    19861 ccaccaacaa cggcgatacg gtcgaggtgt tggctcttgt cagaaagttt attgataact
    19921 tcttcagcat tttggtacaa tttcacgaat tgtacgtttt caagagttgc tttaaattcg
    19981 cggtttcctt taacaatttc aacaccttcg attggtggca agattggtgt agaacctgta
    20041 gcgaaaatca atttttcgta tgattctttg tgctcttttc cttcaacttc cgctgtaact
    20101 actttgttat catagtcgat tgaaagaaca ggtgagttca tgtaaacttt agcaccttta
    20161 gcttccaatt tttctttatc agaatagaac aagccttcag caccgtcaat ttgttcacca
    20221 atccaaagag ccattccaca tcctaggaaa gagatgttag agttttggtc aaatacaaca
    20281 atttcgttct catttccaaa attatccaac atggtattga tacatgctgt accagcgtgg
    20341 ttagcaccga ctacaacgat tttactcata aaaatttcct gccttcattc taaatttacc
    20401 ttactagtat accatttacc gttagcgttt acaagggggg tactattatt tcagcatttt
    20461 ttatcaaaaa taattcccca tttatcctgt tttcaagcct gatgaatttt atgagcatat
    20521 ttcttgactt tttccaaatt ttgtttgtga aaattctaac tttatggtat tataataaca
    20581 tgaaaatgaa atgtaagggc ttcaatttag atgattattt gatattacaa cttattttct
    20641 ataagagaaa ggagttggta gcttgactct tcgttcacat tctgaacggc taatggggac
    20701 tactatcact atttcattag tggatgagca agccgatatc tttctccaaa aatcctttga
    20761 cttgctcaaa gaacttgaat accgcttcaa cgccaatagt caagaatctg agttgatgga
    20821 aatcaattat caagcaggaa tagcccccgt cacggttcat ccagacctgt ttgagctgat
    20881 ttcacttggg ttagagcata gcctagcgct ctctagccac ctcaatatca gcattggtcc
    20941 cttaattcaa acctggcgta tcggtttttc agatgccaag gtcgcccagc ctcaagaaat
    21001 tgaatcggtg ctgcctctaa tcaatcctca tggtatcgag ttagattctt ctacttctac
    21061 tgtgttttta aaacagaaag gaatgaagat cgatctaggt tgtttagcca aaggatacag
    21121 tgcggataag gttgcccaat ttcttaggaa agagggggtg acttctgcct tgatcaatct
    21181 gggagggaat atcctgacca ttggaaaaaa tcaggcaaga ggggataacc catggcaaat
    21241 cgggattcaa gacccagcca atcctagggg aaatcattta atgaccatcc ctgttgtcaa
    21301 taaatctgtc gtgacttcag gcatttatga acgtcacctg accgtcgatg gacaagatta
    21361 ccatcacatt tttgacagtc aaacaggata tcctgttgaa acggaactag cgagtctaac
    21421 aatcatctct gataaatcag tcgatggcga aatctggacg actcgactct ttggagaaag
    21481 acctgcttct atcctctggc aagtcgaaag tttggagggc atcgaagtca tcctcatcga
    21541 taaagaaggc cacctaagct gttcttcagg aattcctact ctatagagac aactgtttca
    21601 atggaatttt aaaattgtat tatgtaaaaa gagaaaggaa atctcatgtt aaaacttatt
    21661 gctattgttg gaacaaattc aaaacgttct acaaaccgtc aattgcttca atacatgcaa
    21721 aaacactttg ctgacaaagc tgaaattgaa cttgttgaaa tcaagaccat tcctgtcttc
    21781 aacaaaccag ctgacaagca agtacctgct gaaatattgg aaattgctgc taaaatcgaa
    21841 gaggcagatg gcgttattat cggtactcct gagtatgatc actctattcc agctgttttg
    21901 atgagcgctc ttgcttggtt gtcttatggt atttacccac ttttgaacaa accaatcatg
    21961 attacaggtg cttcttacgg tacgcttggt tcatctcgtg cccaattgca acttcgtcaa
    22021 atcttgaatg ctcctgaaat caaggcaaat gttcttccag atgaattctt gctctcacac
    22081 tctcttcaag catttaaccc aagtggcgac ttggttgacc ttgatgttat caagaaattg
    22141 gatgccatct ttgatgactt ccgtatcttc gtgaagatta ctgagaaatt gcgcaatgcg
    22201 caagaattgc ttcgcaaaga tgctgaagac tttgactggg aaaatttgta agataggaga
    22261 ccgaaagaat gaaatttgtt ggacttgttg gatcaaacta cgatcaatca tataaccgca
    22321 aactcttgga atttatccgt cgcaatttca aattcaaatt tgaattagaa gtacttgaaa
    22381 tcgacgaagt tccaatgttt aaccaagatg aaaaatggga cgaaagcttc caattgcgtt
    22441 tcttgtataa caagattaca cgtgctgatg gtgtcattat cgccactcct gagcacaacc
    22501 acactatctc agcttcactc aaatctgtac ttgaatggct ttcatacgaa gttcatccat
    22561 ttgaaaacaa gcctgttatg attgtgggtg catcatacta tgaccaagga acatcacgtg
    22621 ctcaagttca ccttcgtaaa atccttgatg ctccaggtgt taatacctac acgcttccag
    22681 gtaacgaatt ccttcttggt aaagctaagg aagcttttga taacaacgga aatatcacca
    22741 acgaaggcac tgttaaattc cttgaaactt gcttagataa ctttgttaaa tacgtaggag
    22801 tcgtttcgaa attgaaaaaa ccaaaaccaa tcgaatcaga agacttggat tgtggaaaac
    22861 caatcgctac aaccatcaca gaagttgacc ctgacgatcc agaatgggta gaaaaagttg
    22921 cagcaatcac tggtgctgtt tctggtgata cctatgtcaa attggaccac ggtatcctaa
    22981 cagttaacca aattgatatg ttcttgaaag ctatgccatt tgaattgaca tacgctgacg
    23041 acaacaacca attcctctac tacaacaacg ctcaccaaga tccagacact atgttcgcta
    23101 aacgtgtacc acctcaatca ggtagccgta tgtcgactgt tcatggttct cttccaccag
    23161 cacgtatgaa gaacgtagag tgggttatcg gaacacttcg caacggaaac caagaatacg
    23221 tccgtacgat cgttccaggt tctcctgcag gtgttatcaa cactcacaac taccaagcaa
    23281 tgtactatcc tgatggatca tacgctggta tcaatgaaat cgtctttaac ttccaaccat
    23341 ggcttgactg gtacctaaaa gagactggtc aacgtttggt gggtggtagc ggaccatttg
    23401 ctcctgctgc cggagatcat ggagacgccg atgctacttc tggcgcttct gattcagggg
    23461 atgctggagg ccacggtggt gacgcagacg ctacagccgg tgcaagttac taatgatagt
    23521 ttttaggaac cattatggtt ccttttttag cgaaaaaaga ctaacaaaca caaactgcta
    23581 gtctctttgt tatcgtttca tctatccttg ttaaaagaaa gaatacttat actcaatgaa
    23641 aatcaaagag caaactagga agctagccgc aggctgtact taagtacggc aaggtgaagc
    23701 tgacgtggtt tgaatttgat tttcgaagag tattattatg aatttgggtc atcaagacta
    23761 cggccatgta atcctttttc acgttgtact tggcgtagtt tttctggtgt aacatcgttt
    23821 ccttcttcgt ccacaatttt gattccttca atgtggtgac gaacagcgcg gcgataacct
    23881 tcgatgtact cctcacgtag tttggcttgt tccacttttt cttctggtgt taagccttct
    23941 gtttttttct ttttagcaag ctcattgata cgagcaattt ttttcggatc catttcttct
    24001 cctttgtaat aagataaagt ccgtttatca aattttattt agtgttaatt tggttaaaac
    24061 aagcaaactt agctgctttc ttggttagtt gtgacaagat tgccaaacga ttttgacgga
    24121 cagcctgatc ttcagccatt accatagtat tttcaaagaa agcatcaatg actgggctaa
    24181 gcgcaaagag ttgtttcaat tgctgacttg caggtcctga taaaacgagt gtttctactg
    24241 cttctgccaa agctttttct tggtcattct caaatagtgc tgaatcaact gtagcaaccc
    24301 cttctgcctt ctcagccagg ttaaaggcac gagaaagtga ttcaacagat ggtttaaaat
    24361 cttcttcctt gcttacttct acgagagcac ttgctgcttc caacatatct gccacaacaa
    24421 agtttgaacc tgcaagaact gcttccttga tatcttttgg agtagagccc atcatcttat
    24481 caacacgagc cttgataaag tccataacct ctgctttatt ttcataagtc aaactgtcaa
    24541 atttcaatgc ataaaggcta tcaatcagct catccatagc aatgtgccaa ccaaaggcat
    24601 ccaagatacg aaccacacct tgagttgcac gacgaagggc ataagggtca ttagaacctg
    24661 atggaatcaa tcctactgaa aagaaactca aaatcgtatc caatttgtct gcaatggcta
    24721 gaactgcgcc gaccttgctc tctggaagtt ctccttcagc tgatgtaggc atgtagtgtt
    24781 cacgaatagc agctgccacc gctggagttt caccagcaag aagggtgtat ttttcaccca
    24841 taattccttg gagttcgtca aattcaccaa ccatacctgt caacaagtca aacttgtaaa
    24901 tggctgctgc acgagcaagg tcaactgttt catccactga caaaccagct ttttctgcca
    24961 aaagtacagt gatttgaccc gtacgaatca tgtgttcacg aagggaacca atcttctcat
    25021 ggaaggtgac attgtttaat ttttcaacaa gatctgaaat caccaatttt tggtcttcac
    25081 gccagaagaa ttctccgtct tccaagcggg ctaccaagac tttttcattt cctttgatga
    25141 catttttcaa acgctctgcg tttccgttac gaacagaaat gaagtttggc aagagttttc
    25201 catcttgatc acgaacaaca aagtaacgct ggtgttcctt catagaagtc accaagactt
    25261 cttctggaac ttcaaggtat ttagcatcaa aacttcccat gaaggcagtt gggtattcaa
    25321 ccaaattcaa gacttcattc agcaaatccg catcaatttc gatacgtaca ccatgttttg
    25381 cctcaatttc cttgatttgg tcaacaatca tttgctcacg ttcacatgga tctgcgatta
    25441 caaactgctt acgaaggtct tcttcatagc tcaatgctga ctgaattttg gtttctttcc
    25501 ccaagaaacg atggccacgg ctcacacgac ttcccttgat atcaaggaaa tccaagtcaa
    25561 actcttgctc atccaagaga acagttaaag tgtgaacagg gcggatgtat tcaaagctat
    25621 ttccagccca gtgcatgctg acagggaaag tcaatgactt caagacatct acaacaccag
    25681 gaacaatggc ttcaactgct tgaccaactt cttccttagt gacatagaca tattcttcac
    25741 ccttgatttc acggaattcg atatcttcaa cagtcaaacc tttcccacgg acaaatcctt
    25801 gagctgcttt ggtgaagttt ccatcactat ccaaggcaat tttctttgct ggtcccttga
    25861 aatcttctgt caaatcagac tgtttgtctg ataaaccagt cacacgaaca gccaaacgac
    25921 gtggtgttga gaaggtttga atggcttcaa aagacaggcg gttttccttg aggaaggctg
    25981 ccattttttc gcctagttgt ttttcacttg gtgtgacaac ataggctggt aattcttcaa
    26041 gaccgagttc tactaataag ttttttgtca tgttttttcc tttacatttt cttcaatctt
    26101 ttttgatatg caccttaggt actggggacg tcgctaacta actctgtgag tctgtatgga
    26161 aatccaatgc taaatttatc aagatttcca acaatctcat caaagtggat ttagctgact
    26221 gatttttgaa cctaaggttt caaaaatccc cacataacag tacagcgatg catatccctc
    26281 tagcaagtct tcgacttgcc tctaacgatt ttagagtaca gtattactca ctattctgca
    26341 tcttctgcta aaagtttaac tcgtgtttct tcatccaaaa gtgggtaacc taggcgtttg
    26401 cgttctgcaa caaaggtttt ggctacaaca cgggccaagt tacggatacg agcgatatag
    26461 cctgcacgct ctgttacaga tacggcacca cgcgcgtcaa gcagattaaa ggtatgtgaa
    26521 catttgagaa catagtcata ggcagggtgt accaagcctt cttctaatgc acgaccagct
    26581 tctttttcaa acttatcaaa attttcaagc aacatttctt ggtccgaaat ttcaaatgaa
    26641 tattttgagt gctcatactc aggctggata aagatttctc cgtattttac accatcagcc
    26701 cactcgatat catagacaga gtctacttct tgaatgtaag aagccaagcg ctccaaacca
    26761 taggtaactt ccgcagtcac agggctagtt gccaatccac cgacttgttg gaaataagtg
    26821 aactgagtga tttccattcc gtcaagccaa acttcccaac caagaccagc tgaaccagtt
    26881 gatgggtttt cccagttgtc ctcaacaaaa cgaatatcgt gctccaaagg attgattccc
    26941 aatttttcca aagactcaag gtaaagttct tggatatttg atggagaagg cttcatgacc
    27001 acctggaatt ggtggtgttg gtagagacgg ttagggtttt ccccataacg accgtcagca
    27061 ggacgacgtg atggctctac ataagctgca ttccatggct caggtccgat agcacgaagg
    27121 aaagtgtaag gactcattgt tcccgcacct ttttcattat cataagcctg cataagcata
    27181 caaccttggt cattccaaaa ttgttgcaaa gtaaggatga tttcctggaa agtcaatttc
    27241 ttagacattg tttactcctt tagtttttat atttcttttt caattaattt ctgctgaaca
    27301 aaccaatcta acaagggaaa agttttttct gtatttgccc ataaatgata agaatctaag
    27361 accgcttgta cactacctaa attttctacc aacttatcta ctgtcaaaaa gctgcgccag
    27421 tattcataaa aaatacttgc atagttctta tcataagtcg aagaaccaaa atcattcaat
    27481 gaatgccaac catacttctt ctgaaaaagt tctacgagag attgattaca aattttttcc
    27541 gcttgaaatt cctcttctgt caagaaatac ttgcgactaa tatattcaac catcccctct
    27601 tcgaaccaga tataagagtc ataaccatca aaatcatcta aaaaatgctc cgaccaatga
    27661 gctaactcat gtcctacaat ctgtaagagg aaattttcag ataaagaatg atagtgactt
    27721 tctattgctt gagtttgctc agaacactcg tagtccatca attgatacaa atacaactct
    27781 ttccaaacag ctaaatcagg cgccataacc attcgtctat tatttgtata ggctggaaca
    27841 gcgctttccc taataatctg tgtagcagca ttaaaatctg accaaataac ggcttgcggt
    27901 aaatcacaga ctgcaagttc attctttaaa aaagattgat aatctttcaa cttttcagta
    27961 tttcttacta caaaatcacg aaatgtagct agttgactat cgtcttttac aagataaagg
    28021 ttgtccacgg ctctcctttc tttcacacaa tagactgaat aagcaaaaga accgcgtccg
    28081 acaatcctag gttgatttaa cctaggggcg tcagaaacgc ggttccaccc taatttatta
    28141 cttcattgtt tttgaaaata ctacagaaag cgccagctca ttattttgcc ctacttggct
    28201 cccactatcc caagctcgct tgaagaacgc cataagactt tctttcctgc tgactattat
    28261 atcaaaaatt agaataatgt acaattcttt ttatgatttt ctagaaatcc acatcatcaa
    28321 ctcgtggagc acccgattga acagcaatcg tttttaaggt ttctctctcc tcatgactca
    28381 gttcaattcc aaagcaatca agattagctt gaatacgaga ggttgtgaca gattttggaa
    28441 gtggtaaaaa tccttctgcc aagctccagg ccaaggctat ctgagcaatc gattttccgt
    28501 gatttgctgc gatttcttgc acttgcttgc tatcaaatag ttctccctga ccaaaaggcc
    28561 cccaagcttc caataaaatt cccttttcac gacagtaagc tacgacttga tcttgataca
    28621 cacctggcgc caagcgaact tgattgaccg caggaacgat agttgcagtt tcaagcaagg
    28681 catccaaatg atggggaaga aaattgctaa cgccgatagc acggattttc ccttcttgat
    28741 agaggtcttc catcgctctc caaacttccg cattgcgagt tttccatgcg tcattttctc
    28801 tgagcggttt tgggttcggc caatgaatca aatacaaatc caaataatcc aagcccagtt
    28861 tttctataga tttttccaaa gcttgacgag tttgctcata ggtttgctga ctattccaaa
    28921 gcttggtagt tacgaacatt tcttcacgtg gaactccgct atctttgatt gcttgaccaa
    28981 cactttcttc attctgataa atcgccgccg tatcaatatg acgataacca gccttcaagg
    29041 cttctaacac tgcatgatag gcttcttctc catccttagc cttaaaagtt ccaaatccca
    29101 atactggaat ttctactcca ttatttaatt gataggtatt catatgcttc tccttctatt
    29161 ttattcatca attatagcat aagacatttt ttaagtagta ctatcttctg taaaaaataa
    29221 gtctgtcaaa tatctaacag acctattttt tcttgcttat tcatcacgac tatagtacag
    29281 ctcatgagct tttaggcgag tattgagcat ctctggtatg gtcacaaagg tataaccttg
    29341 atttttcaaa tactcaatga cccttggcaa ggcattgact gtcggactgt gaatatcatg
    29401 catcaaaacg atagagccgt tagctacttg atgctgaatt tctgtcaaaa tagatgcttc
    29461 atttttactc ttccagtcca gactatccac atcccacatg ataaagctca aatccaagct
    29521 attgcgaata tcatctgtaa tagcaccata aggtggacgc atgagtttag aactagaacc
    29581 cagcacttta gttagcacat cctcagtatc agtaatctgc tttttagctt catcaagaga
    29641 gagttgcgag agaatcggat ggctccaact atggtttcca acaacatgac cttcagattt
    29701 tatcctcttc accaagtcct cattcccaga aacatttttc ccaagcacaa agaaagtcgc
    29761 tttaatatca tatttagcta gggtctctaa tacctgcggg gtcgttgctg gatttggacc
    29821 atcatcaaag gttagagcga caactttttg atatttctta tcaaagtaag attggtacaa
    29881 ggccgcatct ttttcgagta agtacgaaga ttggataaca tcaaagaaag cagatactgg
    29941 caaggctatc tcttctaaat tttcaagcac aggacttgga taaaggataa tctgactatc
    30001 cttgtaatca aaattccatg cagacaagtc ttggtcagag aagtttttta caatctgctc
    30061 actctggtct tgctctattt ttttatcctc tatgaaggag gtcaactctt ttatcagctg
    30121 ttccttagcc ttactagcat ctgaaaacag ttggtcaagt gtaaaaggtt gcccatcttc
    30181 tgttaagtga acctttccta gactggtctt ttcagtctct tcaactttaa aagcaactaa
    30241 atcatagatt tgtttggtca cattacgatt aacgactccc tttaaacctg actcttcttg
    30301 ctctgtatag tagaaaacaa gattgtcctt actttctagc ttgtccttaa catcttgatt
    30361 tatcaactcc ctaacagagg aaatcacttt ctccccttgg agaggataat aggcaatcac
    30421 ttcggcttgc ccctgacgaa aatgctcctt ctgatttccc tcactcaatt gatcatcttt
    30481 ctcttttttg agcgattcaa tcttttgctc aaaacttttt tgctggtaga tcttaaaagc
    30541 aataaatccg cctaataggc aaatagaaat tgctaaaata ccaatcaaag ccaataatac
    30601 atgtctcgtt ttcccgtgtc tgccacgtcc tagtctactt ttattcatat ttatatcata
    30661 acaaatttga gcaataattt caatgataca atttggcaat ccacaattcc tctagcaagc
    30721 caaagcatct tacatcaact ccaacatccg tatctgtaga gattatgtag ttttctatct
    30781 atggaatttc tagtagattg aagctagaat agtagaccta tacttctaaa acattgttag
    30841 aaatcgattt gattgtcctg atcgatttgt cctgttctca tttcatttta ctataaaact
    30901 atgaaaagct aggtcatctg agaagtaatt actatcgaca attgcgatag cgtatactag
    30961 tgcgatttgt ttgtagctct ggtgggtatc accttcacgt tggcgaattt tttctaggtt
    31021 ttgattaacc tgactgcaca gataaggcca taggcgattg atgaaaaaat tctgatgatg
    31081 atcctgaatt tcgatgataa cttggattcc attatctaac tccgccaaga cgtctatact
    31141 agtatagaaa tcttacgctg agtagggcat ggaaggcaag acgtgaatgt tacttccctc
    31201 caaaatcgtc acattttttg ctggcaagtc cagcatatcg cggataaatt gacaaatcat
    31261 tagttgggct gatacctgga tgtctgagaa tcctcctttt cctccttcta ttatagcaca
    31321 tttttaaatc taggtttgct agattctatg cttctatcta tttattcgga aaagaaagct
    31381 aatagcttat ttgaaatttt ctcctctctg ttggatagtc ccgtctatct atgttataat
    31441 gaaagaagga tttaaaatcg gaaaaggagt atttatgcta aaattaggtg tcatcggaac
    31501 tggcgctatc agccatcatt tcatagaagc agcccatacc agtggagaat accaactggt
    31561 cgcaatctat tctagaaaac tagaaactgc agcaaccttt gcttctcgct atcagaatat
    31621 ccaactattc gatcaattag aagtcttctt caaatcttct tttgatttag tctatatcgc
    31681 cagtccaaac tccttacatt ttgctcaggc aaaagctgcc ttgtctgctg gtaaacatgt
    31741 tattctcgaa aagccagctg tcactcaacc acaagaatgg tttgatttga ttcaaacagc
    31801 tgaaaaaaat aactgtttta tctttgaagc agctcgtaat taccacgaga aagcctttac
    31861 tactatcaaa aactttttag cagataagca agtgttagga gcagatttca actatgccaa
    31921 atactcttcc aagatgcctg acttgttggc tggacaaaca ccaaatgtct tttcagaccg
    31981 ttttgctggt ggagccctca tggatttggg gatttatccc ctctatgctg ctgttcgtct
    32041 ttttgaaaaa gccaatgacg cgacttacca tgctcaacag cttgacaata gcattgacct
    32101 aaatggagat ggtatcctct tctacccaga ctatcaagtt cacatcaagg ctggaaaaaa
    32161 catcacttcc aatcttcctt gcgagattta tacaacagat ggaaccttga ctctcaacac
    32221 gattgagcat attcgctcag ctatttttac cgaccaccaa ggaaatcaag tccagattcc
    32281 tatccaacag gctcctcata cgatgactga ggaagtcgct gcatttgcac acatgatcca
    32341 gcaaccagat ctgaatctct accaaacttg gctgtatgat gcaggctctg ttcatgagct
    32401 actatatacc atgcgccaga ctgctggcat tagatttgag gcagaaaaat gaaaaccaaa
    32461 ctaccgactg aatggcaaga actgagtgac caactcggtt tccaagaatt cacccccatt
    32521 caaactcaac tatttgagcc ccttcttgct ggagaaaacc tcctaggagt gagccaaacc
    32581 ggaactggta agaccctagc gtatctccta ccaagtcttc tcagactaca aaagaaaaaa
    32641 gcccaacaac tcttgattct agcaccaaac acggaacttg ctggacagat ttttgatgta
    32701 tgtaaaacgt gggcagaagc tatcggattg actgctcaac tcttcctttc aggttcaagt
    32761 cagaaacgac aaattgaacg tcttaaaaag gggccagaaa ttctgattgg aactcctggc
    32821 cgtatctttg aactcattaa acttaaaaaa atcaagatga tgaatgtgga aaccatcatc
    32881 ctggatgaat ttgaccaatt actagatgat tctcagattc actttgtaga aaaaatcact
    32941 cactacgcac ctcgtgacca ccaactggtc tacatgagtg ccacgaccaa gtttgatcaa
    33001 gaaaagattg tgccgaatac acgcactatt gatctctctg atcaaaaatt ggacaatatc
    33061 cagcatttct acatgcaggt agaccaacgt catcgagtgg atatactacg aaaactggct
    33121 catgtagagg atttccgtgg tctagtcttc ttcaatagcc tgtcagacct tgggaatgcc
    33181 gaggaaaaac tacagtatcg tgatatattg gctgtttccc tcgctagtga tgttaatgtt
    33241 aaatttagaa aagtcatctt agaaaagttt aaagataacc aactaaccct gcttcttgca
    33301 actgaccttt tggctcgtgg aattgatatc gatagcctag aatgtgtcgt aaactttgat
    33361 attcctagag atagcgaaac ctacacacac cgtgctggcc gtactggccg tatgggcaag
    33421 gaaggatatg ttattactct cgtcactcat ccagaagaaa tcaaaaaact taaaaagttt
    33481 gcaagtatcc gagaaattgt cctaaaaaac caagaactct atatcaaata aagccccatt
    33541 gctctataca catccagtgt atggagcttt tttataagca attcaatttt atactcatct
    33601 gctttcaaaa agcattctag tccatctctg attaacgatg gactttatca cctccttctc
    33661 cagtccttgt atgacatctt gaagttgatt catgacatct tccaaagttc gaaaggcttt
    33721 attcttaaat ccacgtttac gaatctcttt ccacacttgt tcaatggggt tcatctctgg
    33781 tgtgtatgga ggaataaatg caaagccaat attagtcgga atctttaagg tacttgattt
    33841 atgccatata gcattgtcca taacgagtaa aaaataatca tctggataag cttgtgaaag
    33901 ctcttctaaa aagacgttca tccactcagt attacatcca ccagctctta agaaaaatga
    33961 ttcgcctgta tgggcatcaa cagctccata acaatagcga aattctcgta tatagtgact
    34021 atggacatgt ggacctactc ctattggaga ccaacaagat cccagtttac tgattctacc
    34081 gaaaccagca tcatcttggt acatcaagcg aaccttatga aaaggtctac tggttttaaa
    34141 gcgctttctt ttcttcttga attgagattt tatttttaga cgcgacaatg gtttgagcat
    34201 ctgctttcct aggatgttct ggacgtggca taatatttcg ccagccatgg cgcttcaaca
    34261 gttgatagaa ggcatcacgt gtgtaggaac gacctaactc ctttttataa gcctgaaata
    34321 aggcatcaat tgtaacaaat tctcctgcct ctgcagcctt caaatgacgg gcaagaaagg
    34381 ctttctcttc ctcaactgtc atatatgcat ggttacgacc accacgtgtt tcttgaagga
    34441 gagagtcgag tccgaactcc tcatattttt ttacattttg
//
LOCUS       DAVLTT010000016        34385 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLTT010000016 DAVLTT010000000
VERSION     DAVLTT010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34385
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.016"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            136..2028
                     /gene="pepO"
                     /locus_tag="VYN15_000862"
     CDS             136..2028
                     /gene="pepO"
                     /locus_tag="VYN15_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV1452209.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEESWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(2151..2780)
                     /locus_tag="VYN15_000863"
     CDS             complement(2151..2780)
                     /locus_tag="VYN15_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1452210.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKYLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFHFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGSATTIAHEKAFNPFF"
     gene            3739..5961
                     /locus_tag="VYN15_000864"
     CDS             3739..5961
                     /locus_tag="VYN15_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV1452211.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            5991..6434
                     /locus_tag="VYN15_000865"
     CDS             5991..6434
                     /locus_tag="VYN15_000865"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV1452212.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(6473..6887)
                     /locus_tag="VYN15_000866"
                     /pseudo
     CDS             complement(6473..6887)
                     /locus_tag="VYN15_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6918..7319)
                     /locus_tag="VYN15_000867"
     CDS             complement(6918..7319)
                     /locus_tag="VYN15_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452213.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFIIRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISL"
     gene            complement(7421..8098)
                     /locus_tag="VYN15_000868"
     CDS             complement(7421..8098)
                     /locus_tag="VYN15_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV1452214.1"
                     /translation="MVVGIAIASGYLNSRLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWEASQE
                     GRPNQMSQKQVKLAAIIISIITFLFAFVTNYIGYEGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIE
                     GNSTKEY"
     gene            complement(8277..8927)
                     /locus_tag="VYN15_000869"
     CDS             complement(8277..8927)
                     /locus_tag="VYN15_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV1452215.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            9039..9881
                     /locus_tag="VYN15_000870"
     CDS             9039..9881
                     /locus_tag="VYN15_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1452216.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            9957..10394
                     /locus_tag="VYN15_000871"
     CDS             9957..10394
                     /locus_tag="VYN15_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV1452217.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            10463..10765
                     /locus_tag="VYN15_000872"
     CDS             10463..10765
                     /locus_tag="VYN15_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452218.1"
                     /translation="MYLVIGIVLAFIVSFWKYNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(10856..11929)
                     /locus_tag="VYN15_000873"
     CDS             complement(10856..11929)
                     /locus_tag="VYN15_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV1452219.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            12085..12762
                     /locus_tag="VYN15_000874"
     CDS             12085..12762
                     /locus_tag="VYN15_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1452220.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            12755..13729
                     /locus_tag="VYN15_000875"
     CDS             12755..13729
                     /locus_tag="VYN15_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1452221.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(13778..15721)
                     /gene="thrS"
                     /locus_tag="VYN15_000876"
     CDS             complement(13778..15721)
                     /gene="thrS"
                     /locus_tag="VYN15_000876"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV1452222.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(15779..16102)
                     /locus_tag="VYN15_000877"
     CDS             complement(15779..16102)
                     /locus_tag="VYN15_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV1452223.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            16961..17470
                     /locus_tag="VYN15_000878"
     CDS             16961..17470
                     /locus_tag="VYN15_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HEV1452224.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAES
                     LYIDETKTTRLLDTPDFPEEFKSLAKAQADELDLLRTKNNLNWAFVSPAVDFIPDGEK
                     TGNYILLLE"
     gene            17717..17986
                     /gene="rpsO"
                     /locus_tag="VYN15_000879"
     CDS             17717..17986
                     /gene="rpsO"
                     /locus_tag="VYN15_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV1452225.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            18720..19334
                     /locus_tag="VYN15_000880"
     CDS             18720..19334
                     /locus_tag="VYN15_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV1452226.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(19627..20376)
                     /locus_tag="VYN15_000881"
     CDS             complement(19627..20376)
                     /locus_tag="VYN15_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV1452227.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            20509..22845
                     /locus_tag="VYN15_000882"
     CDS             20509..22845
                     /locus_tag="VYN15_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV1452228.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            22947..23624
                     /locus_tag="VYN15_000883"
     CDS             22947..23624
                     /locus_tag="VYN15_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV1452229.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAERILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            23611..24408
                     /locus_tag="VYN15_000884"
     CDS             23611..24408
                     /locus_tag="VYN15_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV1452230.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSCGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            24425..25528
                     /locus_tag="VYN15_000885"
     CDS             24425..25528
                     /locus_tag="VYN15_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV1452231.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            25535..25771
                     /locus_tag="VYN15_000886"
     CDS             25535..25771
                     /locus_tag="VYN15_000886"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452232.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVYRTDEVSSKHCFEVVDRTDEVS
                     SKHCFEVVDRTDEVSNHTHGKATLTWFELDFRRV"
     gene            25874..26893
                     /gene="galE"
                     /locus_tag="VYN15_000887"
     CDS             25874..26893
                     /gene="galE"
                     /locus_tag="VYN15_000887"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1452233.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            26895..27848
                     /locus_tag="VYN15_000888"
     CDS             26895..27848
                     /locus_tag="VYN15_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1452234.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(27910..28116)
                     /locus_tag="VYN15_000889"
     CDS             complement(27910..28116)
                     /locus_tag="VYN15_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV1452235.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            28168..28644
                     /locus_tag="VYN15_000890"
     CDS             28168..28644
                     /locus_tag="VYN15_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV1452236.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            28653..29324
                     /locus_tag="VYN15_000891"
     CDS             28653..29324
                     /locus_tag="VYN15_000891"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV1452237.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            29454..29792
                     /locus_tag="VYN15_000892"
     CDS             29454..29792
                     /locus_tag="VYN15_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV1452238.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            29795..30424
                     /locus_tag="VYN15_000893"
     CDS             29795..30424
                     /locus_tag="VYN15_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV1452239.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            30664..31815
                     /locus_tag="VYN15_000894"
     CDS             30664..31815
                     /locus_tag="VYN15_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1452240.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            32128..32877
                     /gene="truA"
                     /locus_tag="VYN15_000895"
     CDS             32128..32877
                     /gene="truA"
                     /locus_tag="VYN15_000895"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV1452241.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IALILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            32867..33640
                     /locus_tag="VYN15_000896"
     CDS             32867..33640
                     /locus_tag="VYN15_000896"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1452242.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            33618..34079
                     /locus_tag="VYN15_000897"
     CDS             33618..34079
                     /locus_tag="VYN15_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1452243.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            34306..>34385
                     /locus_tag="VYN15_000898"
     CDS             34306..>34385
                     /locus_tag="VYN15_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1452244.1"
                     /translation="MKLSYDDKVQIYELRKQGYSLEKLSN"
BASE COUNT         9904 a         6480 c         7886 g        10115 t
ORIGIN      
        1 aaacttggaa ttatgcgttt tatcatggaa agatttttta taatagctaa aaaataatag
       61 ttaaatggtt attaattgca ttccctagtg atttttgtta agataaatgc aaatacaaat
      121 gaaagcgaga acaagatgac acgttatcaa gatgattttt atgatgctat caatggagaa
      181 tggcaacaga cagctgaaat cccagcagat aagtctcaaa caggaggttt tgttgattta
      241 gaccaggaaa ttgaagacct gatgttggcg acaacagaca agtggttagc aggtgaagaa
      301 gtgcctgagg atgctatctt ggaaaacttt gtcaaatacc accgcctagt tcgtgatttt
      361 gacaagagag aagctgacgg tatcacacct gtcttaccac tccttaaaga attccaagaa
      421 ttggaaactt ttgcggattt tacagctaaa ctagcagagt ttgagcttgc aggaaaacca
      481 aacttccttc cttttggtgt atcgccagac tttatggatg ctagaatcaa tgttctatgg
      541 gctagcgctc caagcacaat cttgccagat acgacctact atgcagaaga acatcctcag
      601 cgcgaagagc tcttgactct ttggaaagaa agcagcgcaa atctcctcaa ggcttatgat
      661 ttctctgatg aagaaattga agacttgcta gaaaaaagac ttgaattgga ccgccgagtt
      721 gcggcagtgg tactctctaa tgaagaaagt tcagaatatg ctaaactcta tcatccatat
      781 tcttacgaag atttcaagaa attcgcgcct gccctacctt tggatgactt cttcaaagca
      841 gttattgggc aattaccaga caaggttatt gtagacgagg aacgtttctg gcaagcagca
      901 gagcaattct acagtgagga atcctggtct ctccttaaag caaccttgat tttgagtgtt
      961 gtcaatcttt caaccagcta tttaacagag gatatccgtg ttttgtctgg tgcctacagc
     1021 cgtgcccttt ctggagttcc agaggcaaaa gataaggtca aagcagctta tcatctagca
     1081 caagaacctt tcaagcaagc cctggggctt tggtacgccc gtgagaagtt ctctccagaa
     1141 gccaaggcgg atgtggagaa aaaagtggca accatgattg atgtctataa ggagcgtctg
     1201 cttaagaatg actggctcac tccagaaacc tgtaaacagg ctatcgtgaa gctcaatgtg
     1261 atcaaacctt atattggcta tccagaagaa ttgcctgcac gttacaagga taaggtagtg
     1321 aatgaaactg ccagtctttt tgagaatgct ctagcctttg cgcgtgtgga aatcaagcac
     1381 agttggagta agtggaacca gcctgtagac tataaggaat ggggcatgcc tgctcatatg
     1441 gtcaatgcct actacaatcc tcagaagaac ctgattgtct ttccagcggc cattttacag
     1501 gcgcctttct atgacttgca tcagtcatct tctgctaact acggtggtat tggggcagtg
     1561 attgcccatg aaatttccca tgcctttgat actaacgggg cttcctttga cgaaaatggt
     1621 agcctcaagg attggtggac agagagcgac tatgctgcct tcaaggagaa aacacaaaaa
     1681 gtcattgacc aatttgatgg acaggattct tatggagcaa ccattaacgg taaattgact
     1741 gtatcagaaa acgtggctga cttgggagga atcgcagcag cgcttgaagc agctaagaga
     1801 gaagcagact tctcagcaga agagttcttc tacaacttcg gtcgcatctg gcgcatgaaa
     1861 ggtcgtccag aatttatgaa acttttggct agcgtcgatg tgcacgcacc agccaaactc
     1921 cgtgtcaatg tgcaagtacc aaacttcgac gatttcttta caacctatga tgtcaaagaa
     1981 ggagacggaa tgtggcgttc accagaggag cgcgtgatta tttggtaata caaaaaatct
     2041 agtcatcaga aaaaaggcat ccaatcacgt gtgaaaacct tgataggatg ccttttataa
     2101 tagaaagatt tgctggatag tttacttaaa tttcgattgt catcatcttg ctaaaaaaag
     2161 ggattgaagg ccttttcgtg agcgatagta gtagctgaac catgtcctgg atagacatcg
     2221 tagtttggta gggtgaagag ttgggtctgg atactatgaa ggagttgctc catgctacca
     2281 gtcggaaggt cggtccgtcc gatagtttcg cggaatagag catctcccgt caagactagg
     2341 tgagcatcag gaaagactag ggaaacacca ccgatagagt gccctggggt cggcagaacc
     2401 ttaaaatgaa attcctctag ttggtattct tcgtgaaaga caaaggtgtg ttctgcaggt
     2461 tttgtgacca catctgccat atcatcgtgg cgagggagac cggagagatt atcgacagga
     2521 gtgtagagcc agctggcttc gctctctgcg atatagacag gaggattgcc aaacgtctcg
     2581 cgaaccaagt ccagactcat gatatggtca taatgggcgt gggtcaagag aatagcacag
     2641 atcggtttgt tgatcttctc gattgtctga cgaatggctt cccaatgact accaggatcg
     2701 acgacgatga ggtacttttc gccttctaga taataggtat tttcataggc aacaggattc
     2761 acggttttat ggattttcat actagctcca atctcaaaga atgtactaat actcttcgaa
     2821 aatctcttca aactgcgtca actttatctg caacctcaaa gcagtgcttt gaacagcctg
     2881 cggctagctt tctagtttgc tctttgattt tcattgagta taaattaagt atagcacagt
     2941 tagggagaat aggtaaggat ttaaaatgaa cttaaaaacc agcatgacta gatgaagaca
     3001 ggctggttat caatttatca atattggaaa ggtgtcaatt gcccttcata ggttgcataa
     3061 actccgtcat tagcttgttt gatagacgtg atgtttagag tgctaccgta gttggcttct
     3121 catttgtcgc tatattcact ataagttatc ctactgggca ggttctggtc gttagcatag
     3181 tattgaacga ctgtttttta tagctttgct ggctgaatag gaacaggcag caaactccta
     3241 acattaggag agcaaagata gaaatagcag tttttttcat aggtattctc cttataaact
     3301 aaaggataga agaaagtatc ttgaggattt ttatactctt caaaaatctc ttcaaaccgc
     3361 gtcaacttta tctgcaacct caaagcggtg ctttgagtaa cctgcggcta gtttcctagt
     3421 ttgctctttg attttcattt agtattaatt ccaaaatcca gtcaaggtac cagtgtatgt
     3481 gatacgagtt ccaccgttta tctttcgtat cttcaatgga attgaggaag tcagaaagtc
     3541 tttgggttac aatatggttt ccgttcttct atctctcctt ctatcaccta agtttaaaat
     3601 ctaacttcgt agtatattat gggccaataa ttcagaatta tcaagcaatt ttgaattatt
     3661 tttttcttat tctgttccaa tctagttttc atattcttaa aaaagtgata aaatggtagg
     3721 aagaattgga gagtagagat gccgaaagaa gtgaatttaa caggcgaaga agttgtcgct
     3781 ttaaccaaag aatatttaac ggaagaggat gttcattttg tccataaggc cttggtctat
     3841 gctgttgaat gccacagtgg tcaatatcgc aaatcaggcg agccttatat cattcaccct
     3901 atccaagtgg caggtatttt agctaagcta aagctggatg ctgtaacagt agcttgtgga
     3961 ttcttgcatg atgtggtgga agatacagat gcgactttgg acgatttgga aagagagttt
     4021 ggtcctgatg tgcggatgat tgttgacgga gttaccaagc ttggcaaggt cgagtacaaa
     4081 tcgatcgagg agcaattagc ggaaaatcat cgcaagatgc tcatggccat gtctgaggac
     4141 atccgcgtta ttttggtcaa actgtctgac cgcttgcaca atatgcggac cctgaaacat
     4201 cttcgaaaag acaagcagga gcgtatttcc aaagaaacca tggaaatcta tgccccgctt
     4261 gcccatcgtt tggggatttc cagtgtcaaa tgggaattag aagacttgtc tttccgttat
     4321 ctcaatccaa cggagtttta caagattacc catatgatga aggaaaagcg tagggagcgt
     4381 gaggccttgg tggatgaggt agtcacaaaa ttagaggagt atacgacaga acgtcacttg
     4441 aaagggaaga tttatggtcg tcccaagcat atttactcaa ttttccgcaa aatgcaggac
     4501 aagagaaaac ggtttgagga aatctatgat ctgattgcta ttcgttgtat tttagatacc
     4561 caaagtgatg tttatgccat gcttggttac gtgcatgaat tttggaagcc gatgccaggt
     4621 cgcttcaaag actatattgc caaccgcaag gccaatggtt atcagtctat ccatacgact
     4681 gtttatggac caaaagggcc gattgaattc cagattcgaa ccaaggaaat gcacgaggtg
     4741 gctgagtacg gggttgcggc tcactgggct tataagaaag gtataaaggg gcaagttaac
     4801 agcaaggaat cagctattgg aatgaactgg atcaaggaga tgatggagct ccaagaccag
     4861 gctgatgatg ctaaggaatt tgtggactct gttaaggaaa actatttggc tgaggagatt
     4921 tacgttttta ccccagatgg agctgtccgt tcccttccca aagattcagg accgattgat
     4981 tttgcctacg aaatccatac caaggtcggt gaaaaagcaa ctggtgccaa ggtcaatggc
     5041 cgcatggttc cactgacaac caagttaaag acaggggatc aggttgaaat tatcgccaac
     5101 ccgaactcct ttggacctag ccgtgactgg ctcaatatgg tcaagactag caaggcgcgc
     5161 aataagattc gccagttctt taaaaaccaa gataaggaat tgtctgtcaa caagggtcgt
     5221 gagatgctga tggctcagtt ccaagaaaat ggctatgtgg caaataaatt tatggacaag
     5281 cgccacatgg atcaagttct gcaaaagacc agttacaaga cagaagactc cctctttgcg
     5341 gccattggtt ttggggaaat cggtgcgatt accgtcttta accgtctgac tgaaaaggaa
     5401 cgccgtgagg aagagcgtgc caaggccaag gctgaggcag aggagcttgt caaaggtggc
     5461 gaggtcaagg ttgaaaataa agaaactctc aaggtcaagc atgagggggg agtggttatt
     5521 gaaggtgctt ctggtctcct agtgcggatt gctaagtgtt gtaaccccgt gcctggtgac
     5581 gatattgttg gctacattac caagggtcgt ggtgtggcta ttcaccgtgt ggactgtatg
     5641 aacctgcgtg cccaagaaaa ctacgagcaa cgtctccttg atgtggaatg ggaagaccag
     5701 tactctagct caaataagga gtatatggcc catatcgata tctacggtct caaccgtaca
     5761 ggactgttga acgatgtact gcaagttctt tcaaatacaa ccaagaatat ttcaacggtc
     5821 aatgcccaac caaccaagga tatgaagttt gctaatatcc atgtgtcctt cggtattgcc
     5881 aacctctcta cactgaccac ggttgtcgat aaaattaaga gtgtgccaga agtttactct
     5941 gtcaaacgga ccaacggcta gttgtcctag ctctaactag aaaggctatt atgaaaatca
     6001 ttatccaacg ggttaaaaaa gcccaagtga gtatagaagg ccagattcag ggaaaaatca
     6061 atcagggact tttattgctg gttggtgttg gaccagagga ccaagaggaa gatttggact
     6121 atgctgtgag aaaactggtc aatatgcgga ttttttcaga cgcagaaggc aagatgaacc
     6181 tgtctgtcaa agatattgaa ggagaaatcc tctctatttc tcagtttacc ctctttgcgg
     6241 atactaagaa aggcaatcgt ccagccttta caggggcagc taaacctgat atggcatcag
     6301 acttctatga tgctttcaat caaaaattag cgcaagaagt gcccgttcag acaggtatct
     6361 ttggagcaga tatgcaggtt gagctggtta ataacggacc tgttaccatt atcctagata
     6421 ctaaaaagag ataagaaaga ccaagcccag tcggcttggt ctttctcatc gatcataaaa
     6481 tactccaaaa agaaatcggt tcttgatatg cttgggggaa gtctcttttc aggctttggc
     6541 agatgcgata ggaagggatg agatgtccta ggatgaggag agttccctga aggaaaagtg
     6601 gaatatcact taaagacacc aaggagagaa tcatcaggct atcccatagg agaatttgta
     6661 aagcaaaacg ccagaatctc ggtctaatct gggaatagag ttgactaaag tggtcacaaa
     6721 gttggtttga aagataggtc aatagcacag gatgaaagaa aatgagccaa ccactataaa
     6781 tcaaaatcca gtcccaagta agcccccctt ttaaatgtca aaaatgccag catgattcca
     6841 tcaatgacaa ggagttgaat ggttttgatg aagatgattt ttttcatgct aaaacctcct
     6901 tttccttaga gacactctca taaagagatg tgtttgtcgt aaaagtctgg atagttttct
     6961 cttaggtagt cagctgtcat atagtaaaaa gtagaatggc aagcagtgat aattgacata
     7021 agagatgaaa aacgctgaga actaatgaag gctaagagaa caaaaaatag aaaatcaatg
     7081 gtgagaaccc ctaaatagta gaagcgaatc tttttattga tttgaggata aatctcagcg
     7141 aattgatgtt tgagtcggac gatcaagaga aatagcagga gtccttgagc aaggaagaaa
     7201 attaaaccag agagcaagag ccactcaaaa gatgtctcga gtctaatgat aaaaaatgca
     7261 aatagtagca aatcaataac tgcaattgct ataaaatgga ttctatagag ttttttcatg
     7321 acaagacctt cctcttttat ctaacttcat tctactccaa aagaatggga gttacaacta
     7381 aaatgataaa aataacagaa gggagattct cttaagttgg ctagtattct ttagttgagt
     7441 ttccttctat gtatctaact tcttcatcat tccagacaaa taaagctccg attgcattga
     7501 ggatataaaa gatgtattta ccgatattgg cgaagtttcc ttgaatacca gcttttgtca
     7561 gctgaacgaa attgtaaatc aaccaaaagc cccactgagt tgttagtttc aatgcattca
     7621 aagcattggc aatgagggac agtgcaaagg caatagttgt tacgtaggca aggagattca
     7681 tcttgccctc atatccgata tagttggtca caaaggcaaa gaggaaggtg atgatggaaa
     7741 tgatgatggc cgccaatttt acctgttttt ggctcatttg gttgggtctg ccttcttgcg
     7801 aagcttccca cttctttata gcaaaggtat aaatgaggaa ggtgacggga taggtaatga
     7861 tggccgcctt atttccaagg atataatcaa tagcaccgga caaaatggta ttaacaatac
     7921 caaagtaatt tccccatttg cttaatttcc ccgtgaaacg agtggacaac atggaaatcc
     7981 caacgttggt tacggaaatc aatccaaagg gtacaagagc tgtccatgat ccccagtcta
     8041 caaatttatc gaggcgtgag ttgaggtaac cagatgcaat cgcaatccca acgaccaaag
     8101 caaccccgaa gaggtcaaac tatttagatg tagcaaaaat ttttagtgat tttttcatag
     8161 gttaaactac ctttcttttt ttttcaaata ctctaccacc aaatgaaagt aaaatcaaat
     8221 gatagaaata aaaccctgaa aataaaactt tcagggttgg taggggactt gagaaattag
     8281 ttgattttct cgacatagag ttgttttgca atgtccatat tcacttgtaa atcctcgtcg
     8341 ttactgagga tagtgaaggt attgctgaag ccatcaaact gcttgacttg gagctggtca
     8401 ccgatgtgaa gtgagtgctt gtccagataa tggagaatgt caaaactatc gtgcacccga
     8461 gtcaagcggt aggcgccagc ttccttgata tcagctagtg ggaggttatt gatttcaacg
     8521 aggagttctc ccttggcagg aatagttcct ccgtgggggc aggttttagg gaaacctagc
     8581 agtttatcta gtctttccac gaacaggtca gagacagtat gttccaagac ctcagcttcc
     8641 tcgtgaatct ggtcacttgt atagtctaaa tgatgaacta gaaaaacttc aatcaagcgg
     8701 tgcttacgat agagctcaga gaccagtttg agaccgaggt cagtcagtag atagccacat
     8761 tccttgtcct ttaggatgag attttcactt ttcattcgtt tgatcatttc agttacggca
     8821 gggggagaga cttgcatgcg agccgcaatt tccttgttgg taatcttatg caggtctatg
     8881 ccaatttcat aaatacattt tagatagtct tctttgtttg gggtcattcg tttcctcttg
     8941 tctaatatct ttatctagta tatcaaaaaa agctagattt ctctagctgt gactttttat
     9001 gttatactta ttgcaagaga aaaaacgagg agatggatat gacgaaaata gctcttcttt
     9061 cagatattca tggaaatacc accgccttgg aggctgtttt ggcagatgct cagcagctag
     9121 gagtggatga atactggctt ttgggagata ttctcatgcc agggacagga cgtagaagga
     9181 ttttggactt gttggatcaa ctaccgatta cggctagagt tttgggaaac tgggaagaca
     9241 gtctttggca tggtgtccgt aaggaattgg atagtactcg ccctagtcaa cgctatctct
     9301 tgcgccagtg ccagtatgtt ttagaggaaa tttccctaga agaaattgaa gtgctccaca
     9361 atcaacctct tcaaattcat cgtcagtttg gggatttgac ggtgggaatt agccatcatc
     9421 tgcctgataa gaactggggg cgagagttga ttcatactgg caaacaagag gagtttgacc
     9481 gcttggtgac tcatcctccc tgtgatattg ctgtttatgg acatattcac cagcagttgc
     9541 ttcgttacgg gactggtggg caattgattg tcaatccggg ttcgattggc caacctttct
     9601 ttttggacgc tcagctacgg aaggacttgc gggcccagta tatgattttg gagtttgatg
     9661 acaaaggcct ggtagatatg gacttccgac gggtagatta cgatgtggca gctgaattgc
     9721 agctggctaa agacctgaga cttccctatt ttgaggttta ctatgaaagt ctggtcaatg
     9781 ggatccacca tactcatcat caggaatttt tgagagaatt ggctcagaaa gagggttgcg
     9841 atcgggagtt agacgactgg ttgaaaagtg gtaacgattg acattacaac taaaaagggt
     9901 ataataatag aaaaagaaga gtagaggcag ggtagcctcg taaaaaggag aagaggatgc
     9961 aaattccaag tagatttacc attgcaactc atatgctgat aatcattgcc ctcgagggga
    10021 aggaaagcaa ggtgaccagt gattttctgg ctgctagtgt cggggtcaat cctgtcatta
    10081 tcagaaagat cttgtcccag ttgaagaagg cagagctgat ttcagtagcg cgtggaacgg
    10141 gcggaacaga gattgtcaag gaccttaagg atattagtct tttagatgtt tatcaggcgg
    10201 tcgaatgtct tggtaagaca ggtcaactct tcagtttcca tgacaatccg aatccaaatt
    10261 gccctgtagg agctcatatt catgatgttt tggatcaaaa attggagaga attcagttga
    10321 ctatggaggc agaacttggt cagaccagtc tagaaaaagt cgtggccgat gcagagagtc
    10381 agatgaagga ttaagaggga taaatgccct ctttttttct ttggataatt atgataaaat
    10441 gtagctatta aaggagtaag aaatgtatct cgttatagga attgtattag cctttatagt
    10501 gtcattttgg aagtataata gaagtttgtg gaatccagta ttatttttat tatccctcat
    10561 ttcaagttat ttttatctat cctacctttt ttataaaaat ggatacgaga atgttcagtt
    10621 agctttttat gtatttgcct ttgtattact tccttttttg ctttttctaa gtggcatctt
    10681 tttaatctat aatggggtca ttttgttgaa gcgagaggga cgttccaagc cccattatct
    10741 ctcaatgctc tttgattttt attgactatt agattctatt taaaaagact tataatgcac
    10801 atgaaagtat gtattctagg tcttttgttt tgtatacatt taattttcaa gagtattatc
    10861 tatttttcca tgcctggtaa cgagtatcaa tcaataactg ggtaaggcga cccaaggttt
    10921 ctctttcttc tggagtgagg gattgagctt ggacaaagag atgatgaatg tattcaagcg
    10981 cctttaagga agccaagtca ttgatagagc taataccagc atcaagaata gtgccaaaga
    11041 agaggtcgaa gtagagctga agttcttcgt cagggactgt ggccacccat tctttaaagg
    11101 ttgtgtctac ttgccggcta tcactgttgg tcttatccag ttgaacgaag tgcttgtcct
    11161 caatctgcca actaaaggta tcgtgctggg cgatgccacc cagggcagta ctctgaacga
    11221 tgatttggtg agcaggaatt tccagcatca taccgataat ggaaccttgt ggaatgaata
    11281 tcttgcttct atccattatc ctttgataac ccgcagtctg tgtcaattct tgatggagac
    11341 caggtgcatc aaatgtataa actgctgtga tctgattttg caaactttgc tcaatttggc
    11401 tagcagcata gatagcgaga tttcctccct tggaatgccc agccagaata accttttgct
    11461 taggatgatg ggcaaaaaag ttctttaaat agcgaagggc gtgcttttga gcaggaattt
    11521 ccttcatata ggtcaggtgg aaatcttcct tccagccaat gatactgtca tctgtcccac
    11581 gaaatacaat cagataggta tcgaggctga cacgataagt catagccgca aattgctttt
    11641 gcagttcagg gtcgatgtcg ttgataaaat gggagagttt gcaatttttg aagcgcttgt
    11701 gttgagccaa ttcatctaat aattgaaggc gatttttgct agtaagcatg gtgggctctc
    11761 ttggaacctg aggtgctaga tctaaaagac gttgaggaag tgtggagacc agattatcaa
    11821 aggagaggta ggtgatttct attaaggtta gaatgtctaa ctcattcaag ggaaggtcgt
    11881 aataagaatc atatgcgaca tctttcagat agtcaaaaat attggccata agagctcctt
    11941 tctttttatt tatcttagca aatttccctc aaattagcta gtagcatagc ctgtttgtac
    12001 tggctaaaaa caggctattt caaattcagt ttcagaccat ctagcatgga aaaatctgtt
    12061 ataataatgg aaaaggagaa gcgcatgcac aagattttat taatagaaga tgatcaggtc
    12121 attcgtcaac agattgggaa aatgctctct gaatggggat ttgaagtggt cctggtagaa
    12181 gactttatgg aagttttgag tctatttgtt cagtcggaac ctcatctggt cctcatggat
    12241 attggtttgc ccttgtttaa tggttatcac tggtgtcagg aaatccgcaa gatttccaag
    12301 gtacctatca tgtttctttc ttcgagagac caggctatgg atattgtcat ggcaatcaat
    12361 atgggggcgg atgactttgt gaccaagcct tttgaccagc aggttctttt agctaaggtt
    12421 cagggcttgt tgcgtcgttc ctatgagttt gggcgtgatg agagtttgct ggaatatgct
    12481 ggtgttatcc tcaataccaa atccatggat ttacattatc aagggcaagt cttgaatttg
    12541 accaagaatg aattccagat tttacgcgtg ttatttgagc atgcaggcaa catcgtagca
    12601 cgtgacgacc tgatgcggga actttggaac agtgactttt tcattgatga taataccctc
    12661 tctgtcaatg tggctcgttt gcgtaaaaag ttggaggagc agggattggt aggatttatc
    12721 gagaccaaga aaggaatagg gtacggattg aagcatgctt gattggaaac aattttttct
    12781 agcctatctg cgctcccgta gtcgtctttt tatctatctg ctttctttgg catttcttgt
    12841 cttactcttt cagtttttat ttgccagtct aggaatttac ttcctctact ttttcttctt
    12901 gtgttgcttt gtaaccatat tatttttcac ttgggacata ttggtggaaa cgcaggtcta
    12961 tcgccaggaa cttctctatg gagagaggga agccaagtct cctttggaaa tagctttagc
    13021 agaaaaatta gaagcgcgtg agatggaact ctatcagcag aggtcaaaag cagaaagaaa
    13081 actgacggat ttgctggatt actatacctt gtgggtccat cagataaaga cccccattgc
    13141 agccagtcaa ctcttagttg cagaagtggt cgaccgccaa ctgaagcagc agctagaaca
    13201 ggaaattttc aaaatcgact cctataccaa cctagtttta cagtacctgc gtttagaaag
    13261 tttccatgat gatttgctct taaagcaggt tcaaattgag gacttggtca aggaaataat
    13321 tcgtaaatat gctcttttct ttattcaaaa aggcttaaat gtcaatctac atgaccttga
    13381 taaagaaatc gtgacggata aaaagtggct gctagtggtt attgagcaaa tcatctcaaa
    13441 cagtctcaag tacaccaagg aaggtggtct ggagatttat atggatgacc aagagctttg
    13501 tatcaaagat acgggaatcg ggataaaaaa cagtgatgtc ctccgagtat ttgaacgtgg
    13561 cttttcagga tacaatggcc gtttgaccca gcagtcctct ggacttggcc tttatctatc
    13621 taagaaaatt tctgaagaac tggggcacca gattcgtatc gagtctgagg tcggaaaagg
    13681 aacgacagtg cggattcagt ttgctcaagt gaacttagtc cttgagtaaa aatagatgag
    13741 aaaaagcctc cagattggag gcttttatgc tagactctta tttctcaacg cgtgatttgt
    13801 tggcgatatc agctaggata gcttgaacaa aattatcaac tgagacagtt tgtgtttctt
    13861 tttggccgta gcgacgaacg ttgactgttt cgtcttccat ttctttgtct ccaacaatta
    13921 attggtaagg aatcttgctg gtttgtgaag cacggatctt gaactgcatt ttttcattgc
    13981 gctcatctac gtctgcacgg acaccgcggt cacggagttt cttggccact tcccaagcgt
    14041 agtccacgtg tttttcgtta gatactggga tgagggttac ttggtgtggt gccagccatg
    14101 ttgggaaggc ccccttgtag ttctcaatca agatagctgt gaagcgttcc atagttgaga
    14161 taaccccacg gtggatcatg actggacggt gatcttcgcc atcagctccg atgtatttga
    14221 ggtcgaagcg ttctggcaac aagaaatcaa gttggatagt agaaagggtt tcttcttttc
    14281 caagggcagt tttaatctgg atatccaatt ttggtccgta gaaggctgct tcaccttcgg
    14341 cttcaaagta gtccacgccc atttcatcaa gagctgcacg aagcatggtt tgggcatttt
    14401 cccacatctc atcgttatca aagtacttat gagtatcttg agggtcacga agagagaggc
    14461 ggaagcggta gtcagtcaag ttgaagtctt cataaacatc gataatcaac tgaagggcac
    14521 gttggaattc ttcttggatt tgttctggag taacgaatag gtgaccgtcg ttgagtgaca
    14581 tttcacgtac acgttgaagg ccagtgaggg caccagattt ttcgtaacgg tgcatcatac
    14641 cgatttcagc gatacggatt ggcaattcac ggtaagagtg aacatggtgt ttgaaaactt
    14701 ggatgtggtg cggacagttc attggacgaa ggacaaattc ttccccgtca cccatgtcca
    14761 tggttgggaa catgtcttct tggtaatgat cccagtgacc agaagtcttg taaagctcaa
    14821 cagaagcaag tggtggagtg tagacgtgtt ggtagccaga agccaactct ttgtttacga
    14881 tgtagcgttc caattcacga cggatagtcg caccatttgg caaccagaat ggcaaacctt
    14941 gtcccacttc ttgtgaaatc ataaagaggt caagctcttt accaagttta cggtggtcac
    15001 gttccttagc ttcttcacgc atttgaaggt agtttttcaa gtctttcttg tcaaaccaag
    15061 ctgtaccgta gatacgttgc atcatagcgt tgtcgctgtt tccacgccag tacgcaccag
    15121 ctacatggag aaggtggaag atttggatac gacctgttga tggaacgtga ggtccacggc
    15181 agaggtctac atattcaccc tgacgataga tagtcaaacc gccttcgtct tctgagtgtt
    15241 cttcaatcaa ttccaacttg taagggtcat ttttgaagat ttcacgtgcc tcgtctttag
    15301 tcacttcttc acgaatagat gggaagtttt ctttgacgat tttttgcatt tcttcttcga
    15361 tacgaggaag gtcttcgtta gagatttgac cagctgtgtt gtcagtatcg tagtagaaac
    15421 catcttcgat ggctggacca actcccaagt gaatgtctgg gaaaagacga cgagctgctt
    15481 gggcgaacaa gtgagctgct gagtgacgca agattggaag ggcatcttcg tgatcaggtg
    15541 tcacaatttc gatgcttcca tcttcagtga tagcgcgagt agtgtcgatg agtttgccgt
    15601 tgaatttacc agccaaggct tttttagcta gggaattgct gatagattgg gcaatttcaa
    15661 aagttgttac gccagattcg aattcacgaa cagcgccatc tgggaaagta atgttaatca
    15721 tgatgttctc cttttttatt atttcatagt ttctaagcat tgatttttta tcagcagact
    15781 acttccaagt cctaacgttc aattgctttt ctttatcaga gaggaagttt tccatttccg
    15841 tcagaatgtc tatatccaaa cgttgagaaa gttctaatag ccaccagata ttttctgaaa
    15901 gtttttgttc cagtgtgtag ggtgtttcat catagtagcg tccttgcttt gtcatcacca
    15961 gtcgttggaa atttccaata tcattagata aagccaagag gtcttcttct accgtccact
    16021 tgaaatcatg atgcttaact tccagttcgt gataagcttg tcggattgcc caactgcgct
    16081 ccactaattc ttgcaactcc ataattagta tcctaataaa aaaatgcgac atcctcgaaa
    16141 ggacgtcgca acgtggttcc accttcattt atgtacctca aaagagaggg acacctctga
    16201 ttggctctaa cgtggccacc gttttatgtt ttcataaaaa actcaagagt agtatcagtt
    16261 tagacttcct atgcgtttcc agcaaccacg cactctctag tagaaaggga ctaagtgact
    16321 tgtctctatg gattattata gcatgattgt gagatttttc aaggattttg tgaaagtttt
    16381 ttgtttttca tattttgtag aatatgcttg atgctaatac cagaatccat gcccaccaga
    16441 gcaactgttt catagattag caagtaaatt agtataaact caccaaaggt tatgatagta
    16501 aagtaaaaga gcagtccgtt accaactaac catcaaagtg agaaacggaa acggtagcta
    16561 tagagtaacg atacaatcaa gattaccaga ggtgtaaaga agagaagatt gtttatatag
    16621 tgtaaggggg tcagaaacaa ctagcaagaa caactcataa agtggccaat aaaagaataa
    16681 tatgaccaga tagtagggga gatgggaata gaatctacgc atgataatca cctcgtttta
    16741 aaaaaacaga caacttagat ctcttgctat gattattata gcatgtttaa aacaagaaag
    16801 taaatttgtt gacaaagaag atttttcttt tcactagaat catggttagt tttcttggta
    16861 gaaatatttt gataataatt aagcaagact attgacattg attattaaga gtgtcacaat
    16921 tgttgtaact aaaataatta caacaagaga ggtataaaaa atgaaactag cagttattgc
    16981 agcaaatgga caagcgggga aggcaattgt tgaagaagca gtcaaacgag gacatgaagt
    17041 aacggctatt gttcgttctg aaaacaaaag tcaagctgag tctattatta aaaaagattt
    17101 atttgagttg acaaaagatg atcttactgg atttgatgct gttatttcag catttggtgc
    17161 ttatacacca gatacgctac cgctccacag caaatcaatc gaactattta atcagcttct
    17221 tgctggaaca cagacacgtt ttctagttgt agggggagca gaaagtcttt atatagatga
    17281 aacaaaaacg acacgacttt tagatacgcc tgattttcct gaagaattta agtcactagc
    17341 aaaagctcaa gcggatgaat tggatcttct tcgtacaaaa aataatctca actgggcttt
    17401 tgtcagtcct gctgtagatt ttattcccga tggtgaaaaa acaggaaact acattctcct
    17461 gctagaatga aaaaggaata agccagatta gttatgcaga ttatgctatt ggattggtag
    17521 atgaacttga aaaaggtcat catataaaag aacgtatctc tttacttgaa aaataataac
    17581 tatgagagta ttaatgtttg acagaaaatt taaatcttgg taaaataggg attgtcgtaa
    17641 agacaaataa cttcttcttg gttacaggca tgccaacctg tcactcggat gaagccaaat
    17701 aaaaaggaga aacatcatgg caatctcaaa agagaaaaaa aatgaaatca ttgcacaata
    17761 tgcacgtcac gaaggtgata caggttcagt agaggttcaa gttgctgtcc ttacttggga
    17821 aatcaaccac cttaacgaac acatcaaaca acacaaaaaa gaccacgcta cttaccgtgg
    17881 attgatgaaa aaaatcggtc gccgtcgtaa cttgcttgca tacttgcgta aaaacgacgt
    17941 taaccgttac cgtgagttga tcaactctct aggacttcgt cgctaattca agatacaagt
    18001 gcttaggccg tgttcaattg agcatatctt gataatgaag ctactctaaa ttgggtagct
    18061 tttttgcgtt gtcaccttac ctcgctatac tcaagtataa tctttggtta cggttcctag
    18121 cactgtaagg taaaataaac cagcttttct cccttcgggg agattttttt tgtttcactg
    18181 aaagtttcgt acgatcttcg cctcgtcgcc tagtctataa acgatttatc tagcaagaat
    18241 catgatgcta agggcgtcaa aaatccgtat gaaaataggg aaatgacaca gtgttcgatg
    18301 agcacaagga gtttcatctt tttcactagg attttagccc gggctcaaat cagctctctg
    18361 acttcagagg gcttttttat tgaggtttta tcggtaacaa ttttggagac tacaaaaacc
    18421 tcaaacggta tcagctaatt acaccataaa ggtgcgcagt tactcggctt ttcaagccga
    18481 gtagctgtat gcaagccccc tagaagagcc cactctttac aaagtaaagt atagtatgtt
    18541 atactttaca tggaagtagt cactgaattc cagttagaaa ttactttgta actacgtttt
    18601 gaggaggagt aaaatgcttt cctacgttcg acattaccca ctagcgatag ctaaattaat
    18661 gtgtctgtgc tctcctaaaa tctgctgatt tattactgac taatacagga gtttttttta
    18721 tgggacagac aatcatatct gctattggtg tttatatttc caccagtatc gattatttaa
    18781 ttattttaat tattttattt gcacagctat cacagaataa acagaaatgg catatttatg
    18841 cggggcaata tctaggcaca ggcttacttg taggggcgag tttagttgct gcttatgtcg
    18901 ttaatttcgt gcctgaagaa tggatggttg gattgcttgg tttaatccct atctatttag
    18961 ggattcgctt tgcaattgtt ggagaagatg cggaagaaga agaggaagaa attattgaaa
    19021 gattagaaca aagcaaggca aatcaactgt tttggacagt tacattgctg acaattgcgt
    19081 ctggcggaga taatttaggt atctatatac cttattttgc ttcgttagat tggtcacaga
    19141 ccctcgtggc cttgcttgtg tttgtaatcg gcataattat cttttgcgag attagtcggg
    19201 tgttatcctc tattccgtta atattcgaga caattgaaaa atacgagcga atcattgtgc
    19261 ccttagtatt cattctactt ggactataca tcatgtatga aaatggcacg atagagactt
    19321 ttctgatcgt gtagattttt ttgtttcact aggattttag cccgagctca aatcagctct
    19381 ctgattttca gagggctttt tcattgagta taaatggaca atcttaaagt tactctattg
    19441 tagagtggct tttgatttga ttaggagatt cttataaata tagtaaaatg aaacaaaaac
    19501 aggacaaatc gatcaggaca gtcaaatcga tttctaaaaa tgttttaaga agtagagatg
    19561 tactattcta gtttcaattt gatatataaa tgaaaacctt agctgtttgg ccaaggttca
    19621 tttcttctat gcaagttctt ctcttttctt atctgggttc cagatgaagc ttgcgataaa
    19681 gctaaagatg atggttagga tagcgaggat aatagcaagg atgagggcag ggatgcggat
    19741 aaaccaccag agtggatttg gttttttatc attgtgccat tgtttcgttt cttcgtccag
    19801 acgttggaat tctgtttgaa tacgattggc gactgtttca atgccttcat cattcatttt
    19861 cttgatatct gagatatcga ttggatttcc aaagttcata tcgacacgtt cacggctaat
    19921 caagcccttc aaagtcatgg gaccggtgta ggtaaccggc atgatacgga ccttggccat
    19981 tttggcaatc agtgctgcgc cccccttgac atcgtttgag tggcggctac cacttggaaa
    20041 catgatgaga gagcggtcac tttttttgag aacgttgata ggatatttga tggctgaggc
    20101 gctgggattt tcacggtcga tgggaaaggc gccacacata cgaatccacc aaccaaagat
    20161 acggttggta aagagttctt tttttgccat aaagatgaac tgttttggct tggtcgcaaa
    20221 ggccatataa acaggatccc accaggtacg gtgaggcgca actaaaatat aattttcatc
    20281 ttgattagga attttatcag tattatgata gtgagcattg ccattgatgg accataagag
    20341 caatacaact aatccacgca aataagtata aaacatgcga tctccttcga ttgttttctt
    20401 gttattatta taccttatca aaggagggct ggcaaacttt tcccttgact agatgcatat
    20461 ttgggatgaa attagaattc tgttaaaaaa aatgatataa tagaatttat ggataaaaat
    20521 aagattatgg gattaaccca aagagaagtc aaggaaagac aggctgaggg tttggtcaat
    20581 gactttaccg catcagccag taccagcact tggcaaatcg ttaaacgaaa tgtctttacc
    20641 ctttttaacg ctttgaactt tgccattgct ttggcccttg cctttgtgca ggcttggagc
    20701 aatctggtct tctttgctgt tatctgcttt aacgcttttt ctgggattgt gaccgagcta
    20761 cgagccaaac acatggtgga caagctcaat ctcatgacca aggaaaaggt caaaaccatc
    20821 cgtgatggtc aggaagttgc tcttaatcct gaagaattag tgctaggaga tgtcattcgt
    20881 ttgtctgcag gagagcagat tcctagtgat gccttggttt tggaaggctt tgcggaagtc
    20941 aatgaagcca tgttaacggg agaaagtgat ttggtgcaaa aggaagttga cggcttactt
    21001 ttgtcaggaa gtttcctagc cagtgggtca gttttatctc aagttcacca tgtcggtgca
    21061 gacaactatg ctgccaaact catgcttgag gctaagaccg ttaaacccat caactcccgt
    21121 atcatgaaat cgctggacaa gttggctggt tttactggga agattatcat tccctttggt
    21181 ctggctctct tgctggaagc cttgctttta aaaggcctgc ctctcaagtc atccgttgta
    21241 aactcgtcga cagctctttt gggaatgttg cctaagggaa ttgccctttt gaccattact
    21301 tcgctcttga ctgcagtgat taagttgggc ttgaaaaagg tcttggtgca ggagatgtac
    21361 tctgttgaga ccttggcgcg cgtggatatg ctctgtctgg acaagacggg caccatcacc
    21421 caaggaaaga tgcaggtgga ggctgttctt ccactgacgg aaacttacgg tgaagaggct
    21481 attgccagca tcttgactag ctacatggcc catagtgagg ataagaatcc aactgcccaa
    21541 gccattcgcc agcgttttgt gggagatgtt gcttatccta tgatttccaa tcttcccttc
    21601 tccagcgacc gcaagtgggg ggctatggag ttagaaggct tggggacagt tttcttaggg
    21661 gcacctgaga tgttgctgga ttctgaagtc ccagaagcca gggaggcctt ggagagagga
    21721 tcacgtgtct tggtcttagc tctcagtcag gagaaattag accatcacaa accacagaaa
    21781 ccatctgata ttcaggctct agccttgctg gaaatcttgg accccattcg agagggagca
    21841 gcagagacgc tggactatct ccgttctcag gaggtgggac tcaagattat ctctggtgac
    21901 aatccagtta cggtgtccag cattgcccag aaggctggtt ttgcggacta tcacagctat
    21961 gtagattgct caaaaatcac cgatgaggaa ttgatggcca tggcggagga gacagctatt
    22021 ttcggacgtg tttcccctca tcaaaagaaa ctcatcatcc aaacgttgaa aaaagcgggt
    22081 catacaacgg ctatgacagg ggacggggtt aatgatatct tggcccttcg tgaggcggat
    22141 tgttctatcg tgatggcgga gggagatcca gcaacccgtc agattgccaa tctggttctc
    22201 ttgaactcag actttaatga tgttcctgag attctcttcg agggtcgtcg cgtggtcaat
    22261 aacattgccc acatcgcccc gattttcttg ataaagacca tctattcctt cctgttagca
    22321 gtcatctgta ttgccagtgc tttactaggt cggtcagagt ggattttgat tttccccttc
    22381 attccgatcc agattaccat gattgaccag tttgtggaag gtttcccacc attcgttttg
    22441 acttttgagc gaaatatcaa acctgtcgag ccaaacttcc tcagaagatc catgcttcgt
    22501 gccctaccaa gtgccctcat ggtcgtgttt agcgttcttt ttgtgaaaat ctttggaacg
    22561 agtcaaggtt ggtctgagtt agaaatctca actctcctct attatctctt ggggtcaatt
    22621 ggtttcttat ccgtatttag agcctgcatg ccattcactc tatggcgagt cctcttgatt
    22681 gtctggtcag taggaggctt cctagccaca gctctcttcc caagaatcca aaaactgctt
    22741 gaaatttcaa ccttgacaga acaaacgttg cctgtttatg gtgtcatgat gttggtcttt
    22801 acagtgattt tcatcctgac tagtcgctat caagctagaa aataaagaaa gactgcaatc
    22861 tgtggattgc agttttttta ggtacaagat tgccagccga aatgtggtat aataagaggt
    22921 aatagagttt tggaaagtga gagaagatga tttcaaagag attagaattg gtagcttcct
    22981 ttgtgtcaca gggggctatt ttactagatg tgggaagtga ccatgcttat ctgcctatcg
    23041 agttggttga gagaggccaa atcaaaagcg ctattgcagg tgaggtggtg gaaggtccct
    23101 atcagtctgc ggttaaaaat gttgaggctc acggcctaaa ggagaaaatc caagtccgtt
    23161 tagccaatgg cttggcagct tttgaagaga ctgaccaagt gtctgtcatt accattgctg
    23221 gcatgggtgg tcgtttgatt gctaggattt tagaagaagg tttggggaag ttagctaatg
    23281 tagagcgttt gatcctccag cccaataatc gtgaagacga cttgcgtatc tggctacagg
    23341 atcatggatt ccagattgta gcagaaagaa tcttagaaga agctggaaag ttttatgaga
    23401 ttttggtggt ggaagcagga caaatgaagc tatcagccag tgatgttcgc tttggtccct
    23461 tcttgtccaa agaagtcagt ccagtatttg tccaaaaatg gcaaaaagaa gctgagaagc
    23521 tagagttcgc cctcggacaa atcccagaaa aaaatctgga agaacgtcaa gttctagtag
    23581 ataagattca agctatcaag gaggtgctcc atgttagcaa gtgaagtgat ccaagcttat
    23641 gaagcctttt gccctcagga attttctatg gagggagaca gctgtggtct gcaaattggc
    23701 actttagaca agggtatcca aagggtcatg gttgccctcg atattcgtga agagacggtg
    23761 gctgaagcca ttgaaaaggg tgtagacttg attatcgtca agcacgcgcc tatctttcgt
    23821 cctatcaagg acttgcttgc cagccgtccg caaaatcaga tttacatcga cctgattaag
    23881 catgacatcg cagtttatgt cagccatacc aatattgata tcgttgaaaa tgggctcaat
    23941 gactggtttt gtcagatgct aggaatcgag gagacgactt atctgcagga aacaggtcca
    24001 gaacgtggaa ttggacgtat tgggaatatt cagcctcaga cattttggga attggcccaa
    24061 caggtcaagc aagtctttga cctagatagc cttcgaatgg tgcattatca agagaatgat
    24121 ttgcagaagc ctatttcaag agtagcaatt tgtggtggaa gcgggcagtc tttctataag
    24181 gatgctttgg caaagggggc agatgtctat atcactggtg atatctacta ccatactgct
    24241 caggatatgc tgtctgatgg cttgttagca ttggatccag gtcactatat cgaagtgctt
    24301 tttgtggaaa aaatcgcagc actccttact caatggaaag agaaaaaagg ctgggaacta
    24361 gagattttac ctagtcaagc atcgaccaat cctttccgtc atatctagtt agaaagtgaa
    24421 gacaatgaaa aaagttgcca ttattggagc aggaattgtg ggagcaacag ctgcctacta
    24481 cctctcgaga gaaagtgacc tagaggtgac cgtttttgac catgagcaag gtcaagccac
    24541 caaggccgca gcaggaatta tcagtccttg gttttccaaa cgccgtaata aagcctggta
    24601 caagatggcg cgcttggggg ctgactttta tgtggattta ttagctgatt tagagaaatc
    24661 aggacaaaaa atcgactttt accagcgttc gggagtcttt ctcttgaaaa aggatgaatc
    24721 caagttggaa gaactttatc aactggccct ccagcgcaga gaagaatctc ccttgatagg
    24781 gcaattagcc attctggacc aagcttcagc taatgaatta ttccctggtt tgcagggatt
    24841 tgaccgcctg ctctatgctt ctggtggagc gagagtagat ggccaactct tggtaactcg
    24901 tctgctagaa gccagtcatg tcaagctggt caaagaaaaa gtgactctga cactcttatc
    24961 atcaggctac cagattggcg aagaggtgtt tgatcaggtt attttggcaa ccggagcttg
    25021 gttgggggac atgttagagc ctttaggtta tgaagtggat gtccgtcctc aaaaaggaca
    25081 actacgagat tatcagcttg cccaagacat ggaagattac cctgttgtca tgccagaagg
    25141 ggagtgggat ttgattccct ttgcaggtgg gaaattatcc ttgggcgcta cccatgaaaa
    25201 tgacatggga tttgatttga cggtagatga acccttgctc caacaaatgg aggaggcggc
    25261 cttgcctcat tacccagttt tagctagagc gacttcaagg gctgagcgtg tgggaatccg
    25321 tgcctatacc agtgatttct ctcccttctt tgggcaggtg ccagaattgg caggtgtcta
    25381 tgtagccagt ggactaggtt catcaggcct cacaactggt cctatcattg gttaccatct
    25441 agcccaactg atccaagaca aggagttgac cttggaccct ctaaattacc caattgaaaa
    25501 ctatgtcaaa cgagtaaaaa gcgaataata ctcaatgaaa atcaaagaac aaactaggaa
    25561 actagccgcg ggttactcaa agcactgctt tgaggttgtg tatagaactg acgaagtcag
    25621 ctcaaaacac tgttttgagg ttgtagatag aactgacgaa gtcagctcaa aacactgttt
    25681 tgaggttgta gatagaactg acgaagtcag taaccatacc catggcaagg cgacgttgac
    25741 gtggtttgaa ttggattttc gaagagtata agcattttac tgaaatttta tcaggtagtt
    25801 taggatggca aatgacattc cctgtcaaaa atggtaaaat aagaaaaaat aatctgagaa
    25861 tcgaggaaaa aagatgcaag aaaagatttt ggtaactggt ggtgccggtt ttattggaac
    25921 ccacactgtt attgaattga tccaagcagg ccatcaagtt gttgtggtgg ataatcttgt
    25981 caatagcaat cgtaagagtt tagaagttgt tgaaagaatc acaggagttg agattccttt
    26041 ctatgaggca gatattcgtg acacagttac cctcagagat attttcaagc aggaagaacc
    26101 gactggtgtc attcactttg ctggtttgaa ggctgttggc gaatcaacac gtatccctct
    26161 tgcctactat gacaacaata tcgctggaac tgtcagcctt ttgaaagcca tggaagaaaa
    26221 caactgtaaa aacatcatct tcagttcttc tgcgacagtt tacggggatc cgcacacagt
    26281 gcccatcttg gaagatttcc cactttcagt gaccaaccca tacggtcgta ccaagctcat
    26341 gctagaggaa attttgaccg atatttacaa agcagactca gaatggaatg ttgtcttgct
    26401 tcgttacttt aacccaatcg gagcccatga gagtggtgat ttgggagaaa atccaaacgg
    26461 tattccaaac aatctcttgc catatgtgac tcaagtagcc gttggaaaat tagagcaagt
    26521 gcaagtgttt ggagacgatt acgatacgga agatggaaca ggtgttcgtg actatatcca
    26581 cgttgtcgat ttggctaagg gtcacgttgc agctttgaaa aaaatccaaa aaggttcagg
    26641 actaaacgtt tataaccttg gaactggtaa aggttactca gttcttgaaa ttatccaaaa
    26701 catggaaaaa gcggtgggac gtcctattcc ttaccgcatc gtagaacgtc gcccaggtga
    26761 tatcgctgcc tgctactcag acccagcaaa agctaaagca gaactcggtt gggaagcaga
    26821 actcgacatc acccaaatgt gtgaagacgc atggcgttgg caaagcaagc atccaaatgg
    26881 atttgaagac taagatgatg atttcaatca tcgtcccttg tttaaacgaa gaggaagtac
    26941 ttcctctttt ttatcaggct ctggaagctt tacttccaga tttggaaaca gaaatcgagt
    27001 atgtctttgt cgatgatgga tcaagtgatg ggaccttgga actcttaaag gcctatcggg
    27061 agcaaaatcc ggcagtccat tatatttctt tctctcgaaa ttttggcaaa gaagcagccc
    27121 tttatgcagg cttgcaatat gcgacaggag atttggtggt ggtgatggat gcagacctcc
    27181 aagatcctcc tagtatgttg tttgagatga aaaatgtact agacaaaaat gtagacttgg
    27241 actgcgttgg gacacggaga actagtcggg agggagaacc cttctttcgc agtttctgtg
    27301 ctgttctctt ttatcgcctc atgcaaaaaa tcagcccagt agctctgccg tcgggtgtcc
    27361 gtgattttcg tatgatgaga aggtctgtgg tcgatgccat tttaagcttg actgagtcca
    27421 atcgtttttc taagggactc tttgcctggg tcggctttaa aacccactat ctggactatc
    27481 caaatgtcga aaggcaggct ggcaagacca gttggagttt taggcaactc tttttttact
    27541 ccattgaagg gattgttaat ttttcagatt tccctttgac tatagccttt gtagctggtc
    27601 tcctatcttg ttttctttct ctgctgatga ccttttttgt tgtggttcgg accctcattt
    27661 tgggcaatcc gacatctggt tggacctctc tgatggctgt tattctcttt cttggaggca
    27721 ttcaactctt gaccattggg attctcggta agtatatcag taagatttat ttagagacta
    27781 aaaaaagacc actttatctt atcaaagaaa aaagtgacct tcctgatttt acagaaaaaa
    27841 taaagtgaaa agactataat tttacatgga aatgtgctaa actagaggga gtggattatc
    27901 gccattgatt taggcttcct ggtttccaat cagggcgcga gttgggcaat ttttaacagc
    27961 ctctaagaca tcctgactag gagaaatttc tttttccagt tggtcagggt catcgtaaaa
    28021 acgcacgatt ccattatcgt ggtaatcaaa taaatcagaa taagtttggc aaagtccaca
    28081 ggcgatacat cgttcaggta taagtgtgat tttcatgttc atatttatat tgtaataaga
    28141 aaagtaaaaa aaaacaagga gtaaggtatg gcaaaagaac cgtggcaaga agatatttat
    28201 gatcaagaag aatcaagagc agggcgtcgg catcgaaacc acggaggggc tgataggatg
    28261 gctaatcgta ttttgacgat cctagctagt attttctttg taattgtggt ggtgatggtc
    28321 atcgttctca tctatctatc atcggggggg agtaatcgca cagcagcctt aaaagacttt
    28381 catgattctg atgcaagtgt agtacaaatc tcatcttcaa gcagttctca gcctgagcag
    28441 agttcagagc cagaatctac ttctagtagt tcagaagaag ctgctaatcc tgaaggaacg
    28501 attaaagttc tcgcaggaga aggggaagca gctattgccg ctcgtgcagg aatctccatt
    28561 gctcagttag aggccttgaa tcctgggcac atggctacag gatcttggtt tgctaatcca
    28621 ggtgatgtta taaaaataaa ataggagccg atatgaaaac aattcaaatt gctattgatg
    28681 gtcctgcttc cagcggtaag agtacggtcg caaagattat tgctaaggat tttgggttca
    28741 cctaccttga tacaggagct atgtatcgtg cagcgaccta tatggctctt aagaaccaat
    28801 taggagttga agaagtcgaa gcccttctag ccttgttgga ccaacatcca atcagctttg
    28861 gacgttcaga aactggagac cagcttgttt ttgtaggaga tgtggatatt acccatccta
    28921 tccgtgaaaa tgaagtgacc aatcatgttt ctgctattgc agcaattcct gaagtgcgtg
    28981 agaaactggt ttctctccaa caagaaattg cccagcaagg cgggattgtc atggatggtc
    29041 gcgatattgg aactgttgta ttgccacaag cagaattgaa aattttccta gtagcttctg
    29101 ttgatgagag agcagagcgt cgttacaagg aaaatattgc caagggaatt gaaacagacc
    29161 ttgaaaccct aaaaaaggaa attgctgcgc gtgactacaa ggatagtcat cgtgagactt
    29221 ctcctctcaa acaagcagag gatgctgtct accttgatac aactggtttg aacattcaag
    29281 aagtagttga aaaaatcaaa gcagaagctg aaaaaagaat gtaaatgtag aaaagccgat
    29341 agattgatat cggttttttc taaatttgtc aaaatgctga ttttagggta taatagttgc
    29401 tgttcgagaa attttgattt tcaaagaata gtgaatgatg ataaggagaa atcatgaaca
    29461 atttaccaaa ttgtccaaaa tgtaactcag agtatgtcta cgaagacggt gccctactgg
    29521 tttgcccaga gtgtgctcat gagtggaatc ctgctgaagt tgcagaagta gaagaaggtc
    29581 ttgtcgctat cgatgccaac ggaaataaat tggctgatgg tgatacagta actctcatca
    29641 aggacttgaa agtaaaaggt gcgccaaaag atttgaaaca agggacgcgc gtgaaaaata
    29701 tccgcatcgt agaaggcgac cacaatatcg actgtaagat tgatggtttt ggtgccatga
    29761 aacttaaatc agagtttgtg aggaagattt aagcatgtca aaacactata aacttgtatt
    29821 ttatagccgt atcttcttgt ttctagcggc ttttacggga gtttatcttg aaattactag
    29881 gcatggtggt tttgggatgc ttctctatta cacggttctg tccaacctct tggtaactat
    29941 ttttaccctt tatcttctaa aggttatgag ccgtgtaggt gaaaattggc aaaggccaag
    30001 tctcttgcgc ttaaaaggtg gggtcaccat gagtatcatg attacctgtg tgatttacca
    30061 tttcctcttg gcgcccattg cgactaattt ctatacccta gaaaatttcc tttgccacta
    30121 tatcgttccc atctggtttt tagcggatac cctctttttt gacaaacagg gtcaatacaa
    30181 gatttgggat ccagcagtgt ggaccatttt accctttctg tatatgatgt ttgctctttt
    30241 taatggcttg gttctaaaac tcaatattcc aaatgccaag gataatcctt tcccttactt
    30301 ctttttgaat gtgaacaagg gttggaatgt tgtgtttaag tggtgtctga ttatctttgt
    30361 tgcctatatg gtagcaggat ttattttcta ctttatcaag caaatcaaga gaaagtcatc
    30421 ctaatactct tcgaaaatct cttcaaacca cgtcagtttc catctgcaac ctcaaaacac
    30481 tgttttgaac aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtataag
    30541 atacaaggga ttcattttcg aatttaagaa ggagtctaca aaccaatgag gcttcttctt
    30601 ttcttgctta tttgataact atcaaaaaag tagaagatta agagaaatat agaaagagat
    30661 ttcatgaaac aatttttaga acgggccagc attttggctc tctccctcgt tttgattacc
    30721 tccttttcca tttcgagtgc cctaccagcc atgtttgact attatcaggg ttattctaag
    30781 gaacaaattg agctcttggt gagcttgcct tcctttggaa tcatgatgat gttactgcta
    30841 aatggtttct tagaaaaaat atttcctgag cgcttacaga ttagtttggg cttgctgatt
    30901 ttatcattga gcggtacagc tcccttctgg taccaagcct atccctttgt ctttggaaca
    30961 cggcttctct ttggtttggg tcttgggatg atcaatgcca aggccatttc tattatcagt
    31021 gaacgctacc aaggaaaaag gcgaattcag atgttagggc tacgcgcttc tgcagaggtc
    31081 gttggagctt ctctcattac cttggccgtc ggtcagttgt tggcctttgg ttggacagct
    31141 atctttctag cctatagtgc tggatttttg gtgctgcccc tttatctgct ctttgtccct
    31201 tatggaaaat caaagaaaga agtcaagaaa agagcgaagg aagcaagtcg tttaactcga
    31261 gaaatgaaag gcttgatttt taccttagct atcgaagcgg cagttgtagt ttgtaccaat
    31321 acagctatta ccatccgtat tccaagtttg atggtggaaa gaggattggg ggatgcccag
    31381 ttatctagtt ttgttcttag tatcatgcag ttgatcggga ttgtggctgg ggtgagtttt
    31441 tctttcttga tttctatctt taaagagaaa ctgctcctct ggtctggtat tacctttggc
    31501 ttggggcaaa tcgtgattgc cttgtcttca tccttgtggg tggtagtagc aggaagtgtt
    31561 ctggctggat ttgcctatag tgtagtcttg acgacggtct ttcaacttgt ctctgaacga
    31621 attccagcta aactcctcaa tcaagcaact tcatttgctg tattaggctg tagtttcgga
    31681 gcctttacga ccccatttgt tctaggtgca attggcttac taactcacaa tgggatgttg
    31741 gtctttagta tcttaggagg ttggttgatt gtaatctcta tctttgtcat gtacctactt
    31801 cagaagagag cttaggattg attcctaagt ttttcttttg atactcaatg aaaatcaaag
    31861 agcatagttg attgagtttg gaatagtacg ctgtagctgc taaaatattt ctagaaatta
    31921 atttgacttt tctaatagag ttattcatat cttatttcaa tctactatag aaagctagcc
    31981 gcaggttgct caaaatagtg ttttgaggtt gcagatggaa actgacgtgg tttgaagaga
    32041 ttttcgaaga gtatgagatt tttataccca tacaatattt gttttaggtc cttgtttaca
    32101 gactaatttc ttgataaaat agaggttatg acgagatata aagcaactat ttcctatgat
    32161 ggttatgcct ttgctggctt tcagcgccag tctcatgcgc gtagcgttca ggaagaaatt
    32221 gaaaaaacct tgaccagatt aaataaaggg caaaccatta ctgttcacgg tgctggtaga
    32281 acagatagtg gggttcatgc cctgggacag gtcattcatt ttgacctgcc ttatcagatg
    32341 gatgaggaga aactccgttt tgccttggat acccagtctc ctgaagatat tgatgtgatt
    32401 tcgattgagc ttgtggcaga tgattttcat tgccgttatg ccaaacatag caagacctat
    32461 gagtttattg tggatagagg acgtcccaaa aatcctatgc gccgtcacta tgccacccac
    32521 tttccctacc cactcgatgt ggaacgaatg cagattgcaa tcaaaaagct agagggaacc
    32581 catgatttta ccggttttac agcctctggg actagtgtag aggataaggt tcgcaccatc
    32641 acagaagcta gtttaatagt cgatgagaca ggacaatttt tgacctttac cttttcagga
    32701 aatggtttct tgtataaaca gattcgcaat atggtgggga ctcttctcaa aatcggtaac
    32761 aaccgcatgc cagtagagca gattgctctc atcttggaga agaaggacag gcaacttgca
    32821 ggtcccactg cagcaccaaa tggtttgtat ttaaaggaga ttcgttatga agaataatcg
    32881 tattttagca ctttctggaa atgatatttt tagtggtggt ggactgtcag ctgatttggc
    32941 tacctatacc ttgaacggct tgcatgggtt tgtagcagtg acttgtttga cagccttgac
    33001 agaaaaagga tttgaagtct ttccaactga tgataccatt tttcaacatg aattagatag
    33061 cttgcgtgat gtggaatttg ggggaattaa gattggtctt ctccctactg tcagtgtggc
    33121 tgagaaggcc ttggacttta tcaaacaacg cccaggagta cctgtggtgt tggatcctgt
    33181 cttggtctgc aaggaaacgc atgatgtagc tgtcagtgag ctctgccaag agttgattcg
    33241 ctttttccct tatgtcagtg tgattacgcc taatctccca gaagcagaat tattatccgg
    33301 tcaggaaatt aaaaccttgg aagacatgaa aactgcagcg cagaaattgc atgatttagg
    33361 agcgccagca gtcattatca agggaggcaa tcgtcttagt caggacaagg ctgtggatgt
    33421 cttttatgat ggacagacct ttactatcct agaaaatcca gttatccaag gccaaaatgc
    33481 tggtgcaggt tgtacctttg cctctagcat tgccagtcac ttgattaaag gtgataaact
    33541 tttgccagca gtagaaagct ctaaggcttt cgtttatcgt gctattgcac aagcagatca
    33601 gtatggagta agacaatatg aagcaaacaa aaacaactaa aatcgccctt gtatccctat
    33661 taaccgccct ttctgtggtt ctaggttatt tcttaaaaat cccaacacct acaggaattc
    33721 taactctttt agatgctggt gtcttctttg cggcctttta ctttggtagt cgtgaaggag
    33781 cggtagtcgg aggactagca agtttcttga ttgacctctt atcaggctac cctcagtgga
    33841 tgttctttag cttggtcaac catggcttgc agggattttt cgcaggattt aaaggaaaaa
    33901 gtcagtggtt aggccttatt ttagcaacta ttgccatggt aggaggctac gccttgggtt
    33961 ctactttgat gaatggctgg gcagcagccc tcccagaaat tctaccaaat ttcatgcaaa
    34021 atatggtagg gatgattgta ggatttattc ttagtcaaag tatcaagaag attaagtaat
    34081 actcttcgaa aatctcttca aaccacgtca gcttccatct gcaacctcaa aacactgttt
    34141 tgagcagcct gaggctagct ttctagtttg cactttgatt ttcattgagt ataaagaggt
    34201 tgagtaaaaa gtatttcaaa taagaaaaac gcatagtatc aggtgttgaa tgaactgccc
    34261 cccaaaagtt agacagaaaa aatctaactt ttggggtgtt ttattatgaa attaagttat
    34321 gatgataaag ttcagatcta tgaacttaga aaacaaggat atagcttaga gaagctttca
    34381 aataa
//
LOCUS       DAVLTT010000017        33825 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLTT010000017 DAVLTT010000000
VERSION     DAVLTT010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33825
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.017"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            101..535
                     /locus_tag="VYN15_000899"
     CDS             101..535
                     /locus_tag="VYN15_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1452245.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            547..1737
                     /locus_tag="VYN15_000900"
     CDS             547..1737
                     /locus_tag="VYN15_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEV1452246.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            1748..2239
                     /locus_tag="VYN15_000901"
     CDS             1748..2239
                     /locus_tag="VYN15_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1452247.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            2254..3033
                     /locus_tag="VYN15_000902"
     CDS             2254..3033
                     /locus_tag="VYN15_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1452248.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            3020..3838
                     /locus_tag="VYN15_000903"
     CDS             3020..3838
                     /locus_tag="VYN15_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1452249.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            3838..4131
                     /locus_tag="VYN15_000904"
     CDS             3838..4131
                     /locus_tag="VYN15_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1452250.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            4153..6054
                     /locus_tag="VYN15_000905"
     CDS             4153..6054
                     /locus_tag="VYN15_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV1452251.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNQEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGMHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            6114..7115
                     /locus_tag="VYN15_000906"
     CDS             6114..7115
                     /locus_tag="VYN15_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1452252.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(7225..7560)
                     /locus_tag="VYN15_000907"
     CDS             complement(7225..7560)
                     /locus_tag="VYN15_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452253.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(7571..7813)
                     /locus_tag="VYN15_000908"
     CDS             complement(7571..7813)
                     /locus_tag="VYN15_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452254.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(7824..8366)
                     /locus_tag="VYN15_000909"
     CDS             complement(7824..8366)
                     /locus_tag="VYN15_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV1452255.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADRIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITAIDPDMLSEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLRILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(8382..8576)
                     /locus_tag="VYN15_000910"
     CDS             complement(8382..8576)
                     /locus_tag="VYN15_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1452256.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            8742..9692
                     /gene="rsmH"
                     /locus_tag="VYN15_000911"
     CDS             8742..9692
                     /gene="rsmH"
                     /locus_tag="VYN15_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV1452257.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLARIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            9704..10021
                     /gene="ftsL"
                     /locus_tag="VYN15_000912"
     CDS             9704..10021
                     /gene="ftsL"
                     /locus_tag="VYN15_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV1452258.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            10025..12277
                     /gene="pbpX"
                     /locus_tag="VYN15_000913"
     CDS             10025..12277
                     /gene="pbpX"
                     /locus_tag="VYN15_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV1452259.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRTMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            12279..13259
                     /locus_tag="VYN15_000914"
     CDS             12279..13259
                     /locus_tag="VYN15_000914"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV1452260.1"
                     /translation="MFISISAGIVTFLLTLVEIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            13868..15973
                     /locus_tag="VYN15_000915"
     CDS             13868..15973
                     /locus_tag="VYN15_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1452261.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMSQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLNPFFRPELLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            16425..16760
                     /locus_tag="VYN15_000916"
                     /pseudo
     CDS             16425..16760
                     /locus_tag="VYN15_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(16827..17309)
                     /locus_tag="VYN15_000917"
     CDS             complement(16827..17309)
                     /locus_tag="VYN15_000917"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV1452262.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEEVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(17404..18888)
                     /locus_tag="VYN15_000918"
     CDS             complement(17404..18888)
                     /locus_tag="VYN15_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV1452263.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTGRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDATRAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            19041..20651
                     /locus_tag="VYN15_000919"
     CDS             19041..20651
                     /locus_tag="VYN15_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV1452264.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGAKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKQVLAPWDAFCVEMTD"
     gene            complement(20795..22193)
                     /locus_tag="VYN15_000920"
                     /pseudo
     CDS             complement(20795..22193)
                     /locus_tag="VYN15_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
     gene            22371..23816
                     /gene="cps4A"
                     /locus_tag="VYN15_000921"
     CDS             22371..23816
                     /gene="cps4A"
                     /locus_tag="VYN15_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV1452265.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYEVDINYYVRLNFTSFLKLIDLLGGIDVYNDQ
                     EFTAHTNGKYYPAGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMIDLVNTQLESGGKYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            23818..24549
                     /locus_tag="VYN15_000922"
     CDS             23818..24549
                     /locus_tag="VYN15_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV1452266.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLVESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNIPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRVQYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKEFFVDNPRKIIMDQLI"
     gene            24558..25250
                     /gene="cpsC"
                     /locus_tag="VYN15_000923"
     CDS             24558..25250
                     /gene="cpsC"
                     /locus_tag="VYN15_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEV1452267.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGGIGTSVIVLLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     gene            25260..25943
                     /locus_tag="VYN15_000924"
     CDS             25260..25943
                     /locus_tag="VYN15_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV1452268.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARTGYKTLLIDGDTRNSVISGVFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVIQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILVTAIGEVNKRDVQKAKQQLEQTEKLFLGVVLNKLDISVDKYGVY
                     GSYGNYRKE"
     gene            25952..26593
                     /locus_tag="VYN15_000925"
     CDS             25952..26593
                     /locus_tag="VYN15_000925"
                     /inference="COORDINATES: protein motif:HMM:NF014453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1452269.1"
                     /translation="MIKMYFVFKNILDRFLAFFLFITLIIIPIIPITILVIWIEDPGD
                     VFFFQDRIGLNGKSFKVIKFRSMYKDADQRIKKSIISGEIDRLNFKEHSQSMTTKVGK
                     VIRKLSIDELPQLVNIIKGDMAIVGPRPLQQFEITHHILTHKEMETTLKMSKRLSVKP
                     GLLCYWQVTPNKNDIPFSDRMNLDLLYIDNVSFKTDFLLILKGFYTVLMGNNN"
     gene            26595..27386
                     /locus_tag="VYN15_000926"
     CDS             26595..27386
                     /locus_tag="VYN15_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019788257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4422 domain-containing protein"
                     /protein_id="HEV1452270.1"
                     /translation="MKNIKILVATHKKYKMPSDSNMYLPIHVGCEGKKNLGFQGDNSE
                     ENISNLNPYYCELTGLFWAWKNLDCDYLGLVHYRRYFTKMTKRYNESINIDDVILNRF
                     EVEKLLENSDIIVPKRRKYYIETLYSHYDHTFDGSHLDLARKMIEMKNPEYLSSFDKV
                     MEQRSGYMFNMFIMKKELADDYFSWLFPILDSMYESMDLSGLTDFEARLFGRVSELLF
                     NVWLVKSNLTPKEVPFMYMEKVNLFKKGISFLMAKFFGKKYGQSF"
     gene            27406..28623
                     /locus_tag="VYN15_000927"
     CDS             27406..28623
                     /locus_tag="VYN15_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymerase"
                     /protein_id="HEV1452271.1"
                     /translation="MKVVIKRKSLPEILALSALTIFLVVSILDVTFYVQYLPKVVYKI
                     LIAISLILLVIKELYKRKFDYRTIISLFATVLMYLLIGRVSTLNSNIAIGIIFIYALR
                     DIPFKSVAKTSLAVSVLILLFVITSAKLGVIINYLEISGTRVRSYLGFRYALFPSILM
                     MNIVAIVFYLKQNKIQYWQWLLLSLSAYWLYDETDSRLTFYSSCILLICSLLIRWIPE
                     LFSKFGYIFKAFKLTFIINAVVSFWVSFTYLNLSHSYINNLFLKLDYILGGRIYLMNK
                     SLNLYGFGLFGRPVEWNGNGLTIEGVRNYQTYLYVDNLYVQILQKFGLLALGIMLLVL
                     TLTLFKVIKRREWVLSFILILMSFHSMIDDLNLYLHYNIFWILLGSLIYPDYQFSDES
                     DEELGENSFEEII"
     gene            28719..29519
                     /locus_tag="VYN15_000928"
     CDS             28719..29519
                     /locus_tag="VYN15_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HEV1452272.1"
                     /translation="MSDIKIIQDKILIILKEFISICEENNLTYYALGGTLLGAVRHKG
                     FIPWDDDIDIGMPREDYEKFKILAPDLLPSNLKIVNNPLNLDITQLVDKNVIVKIANS
                     ENNVFIDIFPLDGYPEKGFFAAKLHSFRLLFQRMLCKISVLDQLEDKDRGTVENLIVK
                     ISKMLRIQKVLPKDTLVENLHKVIQKYDFKTSRYVGNVLGRYREREIVPKEYFKEPVS
                     LIFEDTMINCPTKYKEYLSEIYGDYMKLPSVEDRVAHNIELISVGDAE"
     gene            29535..30653
                     /locus_tag="VYN15_000929"
     CDS             29535..30653
                     /locus_tag="VYN15_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1452273.1"
                     /translation="MGKKICIVKWILDDSGGGERVAVSLANELTKKYEVHLIGITTKQ
                     SDLFFKINSQVRYSNFFDHRVRLSKNILKISKMLRKYFIDNEIEVGFGIGISANVFLS
                     LAGIGTQTKVVLCDHTNSITDNREFSQKFQRYVGTKLADKIITLTQEDRENYIKKYGV
                     PEERICYIYNWKEAALSDVSYNKKSTKIVTVGRFDYQKGYDYLIQVAKKVLEKRADWT
                     WEIYGSGNQDEVEKIRDLINENDLQDRLVIKGLEKNQDLIYGDKGIYVMTSRYEGLPL
                     VLLEAQQYNLPIASFSCPTGPNEIVEDGVNGYLVECYDVEAMSNRLLELMNDKELRNR
                     FSSHAKDNIEKFNKDRIIHQWIDLIEEVSGGGKCLIKY"
     gene            30635..31651
                     /locus_tag="VYN15_000930"
     CDS             30635..31651
                     /locus_tag="VYN15_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1452274.1"
                     /translation="MSNKILTITVPTYNIENYIGKCIESFKAVNPTYYSDFEVLIIND
                     GSTDNSVQVVKDLMEGSTLDLRIITKENGGHGSTINRGIKEASGKYFKVIDGDDWINV
                     PEFESLLDKLREINTDLVISDYTEQHVYNNSTIFKEFSSYLIPNQETRGIPSKWTPMH
                     ALVYKTSILKDNAITISENTFYVDQEYTMLPLQFVENYIYFKLDIYQYFLGRADQSMN
                     IDIMRKRADHHERVTKRILDLYKESYTQKPEIEKVVSDSLQYLVNKQNILYVMNEELD
                     KVYELFSYSEKSGFKFKFETKTKTSNLLYVNYKTKYLFNLVIKNLVKRKANSLEKEFQ
                     EKGF"
     gene            31756..33171
                     /locus_tag="VYN15_000931"
     CDS             31756..33171
                     /locus_tag="VYN15_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003009066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HEV1452275.1"
                     /translation="MKVLKNYAYNLSYQLLIIILPIITTPYVTRIFSSDNLGTYGYFN
                     SIVTYFLLLATLGIGNYGTKEISGNRKAIHQNFWGIYSIQLGASLFSTFLYVIVCLIL
                     PAMQNTVAYILGLSLFSKGLDISWLFQGLEDFRKITVRNITVKVIGVTSIFLFVKSAS
                     DLYLYVFLLTIFELLGQLSMWVPAREFIGKPHFDWLYAKQHLKPVILLFLPQVAISLY
                     VTLDSTMLGSLASIRDVGIYDQSLKLVKILLTLVTSLGSVMLPRVSNLLSSGDHKAVN
                     KMHEISFLIYNLVIFPIMAGMLIVNDDFVTFFLGQDFQEARYAIAIMIFRMFFIGWTN
                     IMGIQILIPHNKNKEFMLSTIIPAIVSVGLNLLLLPKLGYIGAAIVSVLTEALVWAIQ
                     LYYTRTYLKDVLIIRTMIKIILASAIMYSVLLVSKTYIHFSPTINVLVFVVLGGIIYL
                     FSVLSLKVIDVIELKQVIRKN"
     gene            33173..>33825
                     /locus_tag="VYN15_000932"
     CDS             33173..>33825
                     /locus_tag="VYN15_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEV1452276.1"
                     /translation="MHKFKDINLDLLKVIACVGVVLLHTEMGGFKETGSWNFSTYLYY
                     LGTYSIPLFFIVNGYLLLGKKEITYSYILQKVKWILITVLSWTLIVWLFKRDFSVNPI
                     KKLIGSLVQKGYFFQFWFFGALILIYICLPVLKQFLNSKRSYLYFLSVLLVIGLIFEL
                     TNIVLQMPIQAYVIQTFRLWTWLFYYILGGFISQFDKNTIKNGFKRWMKVIAVLLLLV
                     "
BASE COUNT        10465 a         5587 c         7326 g        10447 t
ORIGIN      
        1 gctaatattt ttttaaaaaa actattgaca agataaaaat aaaggattac aatggggaat
       61 ataaagtaaa ccggtaaacc taaacaagaa aggagaaaag atgaaaattg tacttgtagg
      121 gcatggacat tttgctacag ggatttatag ttctttacaa ttgattgcag gcaatcaaga
      181 aaatgtggag gcgattgact ttgtggaagg aatgtcagca gatgaactca agcaaaaaat
      241 cttacttgca atttcaaatg aagaagaagt tttaatccta agtgatctct tgggaggatc
      301 gccattcaag gtttcttcta ccataatggg agaaaatcca gccaaaacaa tgaatgttct
      361 ctcgggtttg aacttagcca tgttaatgga agcagtcttt gctagaatgg ctcatagctt
      421 tgatgaagtt gttaataaat cagtagtggc ggcccagggc ggagtcgtaa atggtaaaga
      481 attgttttca acggatgcag aggaagagga agaagatttc gaatcgggta tttaaagggt
      541 aaaagaatga taaaaaaggt tacgattgaa aaaataaaat cgcctgagcg cttcttagaa
      601 gtaccacttc tgacgaaaga agaagtcggc caggcaatcg ataaggttat tcggcagtta
      661 gaactcaacc ttgactattt caaggaagat ttcccgacgc cagctacctt tgataatgtc
      721 tatccaatca tggataacac ggaatggacc aatggtttct ggacaggaga actgtggttg
      781 gcttatgaat acagtcaaca ggatgcattt aaaaacatcg ctcataaaaa tgttctttct
      841 ttcctggatc gtgtcaataa gagagtagaa ttggatcacc atgatctcgg cttcttgtac
      901 acaccgtctt gtatggctga atataagata aatggagatg gagaggctag agaagcaacc
      961 ttgaaagctg cagataagtt gattgaacgc tatcaagaaa aaggtggttt tattcaagct
     1021 tggggagact tgggcaagaa agagcattac cgtttgatta tcgactgctt gctcaatatc
     1081 caactcttat tctttgctta tcaagaaaca ggcgatcaaa aatactacga tattgcagaa
     1141 agtcatttct atgcttcagc taataatgta atccgtgatg acgcttcgtc cttccacacc
     1201 ttctattttg atcctgagac aggtcaaccc tttaaaggtg taacgagaca agggtatagt
     1261 gatgattcat gctgggcacg tggtcaatca tggggagtct atggtattcc tttgacttat
     1321 cgtcacttaa aagacgagtc ctgctttgac ttgtttaagg gtgtgaccaa ttatttcttg
     1381 aatcgtctgc caaaagatca tgtgtcctat tgggatttga tttttaatga tggtagtgct
     1441 caatcacgag attcttcagc aacagctatc gccgtctgtg ggattcatga aatgctaaaa
     1501 catctcccag aggtggatgc tgacaaagat atttataaac atgctatgca tgccatgctt
     1561 cgttccttga tcgaacatta tgcaaatgat caatttaccc ctggtgggac aagtctcctc
     1621 cacggtgtgt actcatggca ttcaggtaaa ggagtggatg aaggcaatat ctggggtgac
     1681 tactattacc tagaagccct tatccgtttc tacaaagact ggaacctata ttggtaggag
     1741 gagaaatatg acaatgccaa atattattat gacccgtatc gatgaacggt tgattcatgg
     1801 gcaaggacaa ctttgggtaa aatacctagg ttgtaatacg gtcattgttg ccaatgacga
     1861 agtaagcaca gacaagatgc aacaaactct gatgaaaaca gttgtgccag actcagttgc
     1921 catgcgtttc ttccctttgc aaaaggtgat tgatatcatt cacaaggcta atcctgctca
     1981 aacgatcttt atcgttgtaa aggatgtgaa ggacgcttta accttggtag aaggtggtgt
     2041 ccctatcaaa gaaatcaata ttgggaacat tcacaatgct actggtaaag agcaagtgac
     2101 acgctccatc ttcctgggtg aagaggacaa ggcggccctc aaggaattga gccaaactca
     2161 tcaagtaaca tttaatacga aaacaactcc aacaggaaat gatggagctg ttcaagtcaa
     2221 cattatggac tatatttaaa agaggagatc gttatgtcga ttaatgtatt tcaagcgatt
     2281 ttaattggat tatggacagc tttctgtttt agtggaatgc tgttaggaat ttacaccaat
     2341 agatgtattg ttctgtcatt tggtgtcgga attattctag gtgatttgcc tactgctctt
     2401 gcaatgggag ctattggtga attggcttat atgggattcg gtgttggtgc tggaggtact
     2461 gttccaccaa acccaatcgg acctggtatc tttggtacct tgatggctat cactagtgct
     2521 ggtaaagtca gtccagaagc ggctcttgcc ctctctactc cgattgctgt ggcgattcaa
     2581 ttcttacaaa ctttcgccta cactgtacgt gctggtgcgc ctgaaacggc gatgaagcac
     2641 ttgaaaaacc ataatttgaa gaaattcaag ttcactctaa atgcaacaat ttggttgttt
     2701 gcctttattg gatttacctt gggttgcttg ggtgcccttt caatggatac cttgttgaaa
     2761 ctcgtagact acattccacc agtattgctt acaggtttga cagttgctgg taaaatgctc
     2821 ccagctatcg gttttgcgat gatcttgtca gtgatggcta agaaagagtt gattcccttt
     2881 gtcttgttgg gatatgtttg tgcagcttat ctaaacatcc caacaattgg tattgcaatt
     2941 gtaggtacta tctttgcttt gattgaattt tataacaagc caaaaacagc ggatcatgtg
     3001 gtagaggagg aagcacacga tgactggatc taacaaatta acaaaacgtg attatcttaa
     3061 aacgtctttg cgggcattct tttgtcaaaa tggatttaac tatagtaact atcaagggtt
     3121 gggatatgcc aatgtgatgt atcctgcttt gaaaaaacac tatggagagg atcaggaagg
     3181 tttctaccaa gccttggaag aaaactgtga attctataat accaacccac acttcctgcc
     3241 ttttattacc agcttgcatc ttgtaatgtt ggaaaatggc cgaccaacaa aagaaacacg
     3301 tagcatcaag atggccttga tgggaccatt ggcaggtatt ggggattctc tttctcaatt
     3361 ctgtttagct ccattgttct caaccatcgc agcttcgttt gctcaagaag gcttggttgt
     3421 cggtccaatc ttgttcttcc ttgcgatgaa tacgatttta acagcgatta aattgtcaac
     3481 tggtctgtat ggatacaaac taggaacaac tgtgattgat aaactaagcg aacagatggc
     3541 aacgatttct cgtattgcca atattatcgg tgtaaccgta attgctggtt tggcagcgac
     3601 atctgttaag attatggtgc cgattacctt tgctgcaggg gaagttaaag cagacgctaa
     3661 acaaagtatc gtaagtattc agggaatgct tgataaggtt gctccagctc ttctaccagc
     3721 cctatttaca cttttagttt actacttgat caaagaaaag aaatggacaa catataaact
     3781 cgttatttta acagttatca tcggaattat cggaagctgg cttaagatta tagcttaatg
     3841 gatacaacat tgttttatgg aatagtgatt gtcttggcag tgagtcccct tttactgtca
     3901 agctttcatt ctattcgtca gcaaaagttg cttcgcaaac agatggagca acgacaagag
     3961 tatttagctt ctttaacatc tggtgatgaa gtgttgttat tgtctggaat tcatggaaaa
     4021 atcatttcta tcaaagatga cttggtctcc ttgcagattg caaaaggtgt ggtcatctat
     4081 gtagaaaagg aaagtgtaat gggaaagaca aaagaactgc tttttaagta gttctttttc
     4141 tggtaataga taatgaaaga agaaagaaga caattttttg aaagagtcga tggaaaccaa
     4201 tgtcgtgatt atatcttgtc ccactgctca aaagactatg agaaagtcaa gagttccctt
     4261 gaacgcttga tggacaatcg ttttatgttt gatagtcctt gggatatgga gccttgttca
     4321 aaaatccatc aaatccagcc gatggtatgg gatcaagtat ttgaagatga tccagaatgg
     4381 tcttatatgc tcaatcgaca agaatatctc ttgcagttta tgatagggta tctggtagaa
     4441 ggagataagg actatattca aaagtgcaag ttctttctat ttgattggat tgagcaggtg
     4501 agagaatttt ctcctcaatc cttgatgact agaaccttgg atacgggtat tcgttccttt
     4561 acttggttga aactactctt gctcctcttg aaatttgact tgctagagga gaaagaacta
     4621 gagaaaattt tggtcagtct agaaaagcag attgacttta tgaaaagcta ctatcgcgcc
     4681 aagtacaccc ttagtaactg ggggatttta caaacgattc cgatgcttgc tatctatcat
     4741 ttcttttcag ataagatgga cctagaagaa gcttaccatt ttgcttcaga ggagttgaaa
     4801 cagcaaattg agacacagat tttaggagat ggaagccagt ttgaacagtc gattctctat
     4861 catgtagagg tttataaagc cttgctggat ttgtgtctct tgcttccaga cttgcaagat
     4921 agttaccaag agttgctgga aaagatggcg acctatattc aaatgatgac aggcttagat
     4981 ggacggactt tggcttttgg tgatagcgat tctacagaaa cgacagaaat gttgagcctg
     5041 tctgctgtgg ttttgaacca ggaagacctt cttaacggtc tggatgttaa agtcgatttg
     5101 cttagcctct tgttcctggg gcgagaaaag gtcaagcgac tgcaggaatt tgaaaggaga
     5161 gcttggcagc ctaagtccat gatctttgaa gactctggac atgtctgcat taaggatgaa
     5221 catcgttatc tatttttcaa aaatggtccg ctaggaagtg cccatagcca tagtgacgag
     5281 aatagttttt gcttacagta tcaaggacaa cctattttca tagatgctgg gcgttattct
     5341 tatcgggaga tatatgaacg ttatctctta aagagtgctt ggagtcattc gacctgcatt
     5401 gtagatggga aagctccgga aagaatcacg ggatcctggg aatatgaata ctatcctcac
     5461 tccctgtttt gtcaccataa agaaagggag ggaatgcatt atattgaagg ggcttattgg
     5521 tcagcagaac ctgatttgcc ttatcttcac aagagaaaaa tcctcatgtt ggtagaggat
     5581 gtctggctct tggtggatga catcaggtgt caaggtcagc atgaggcgtt gactcagttt
     5641 atccttgaca aggatgtgac ctatcaagat gggaaaatca atcagttgag actatggagt
     5701 gaagttgatt ttgatttgga agataccatc atttctccta aatacaatga gcttgaaaga
     5761 agtagcaaac tcaccaagcg ccaattcttt gagaatcaga tgctggatta taccatcatt
     5821 gcgcatgaga gttttgaaat catccgtcat tctgtctacc agacagatga tcgtgaagtg
     5881 gaaaatgctc tggcttttga agtgaaaaat gacgaaacag acaagctgat tctgttatta
     5941 agcgaggata tttgtgtagg tgaaaaattg tgcctcgttg acggaacaaa aatgcgtgga
     6001 aaatgtctag tatatgataa aataaatgag agaatgattc gcttgcagtg ctagaaatag
     6061 gcattttgaa tagtgaatat gttataataa gtattagtag gaggtgtttt agattggaga
     6121 agaaactgac cataaaagac attgcggaaa tggctcagac ctcgaaaaca accgtgtcat
     6181 tttacctaaa cgggaaatat gaaaaaatgt cccaagagac acgtgaaaag attgaaaaag
     6241 ttattcatga aacaaattac aaaccgagca ttgttgcgcg tagcttaaac tccaaacgaa
     6301 caaaattaat cggtgttttg attggtgata ttaccaacag tttctcaaac caaattgtta
     6361 agggaattga ggatatcgcc agccagaatg gctaccaggt aatgatagga aatagtaatt
     6421 acagccaaga gagtgaggac cggtatattg aaagcatgct tctcttggga gtagacggct
     6481 ttattattca gccgacctct aatttccgaa aatattctcg tatcatcgat gagaaaaaga
     6541 agaaaatggt cttttttgat agtcagctct atgaacaccg gactagctgg gttaaaacca
     6601 ataactatga tgccgtttat gacatgaccc agtcctgtat cgaaaaaggt tatgaacatt
     6661 ttctcttgat tacagcggat acgagtcgtt tgagtactcg gattgagcgg gcaagtggtt
     6721 ttgtggatgc tttaacagat gctaatatgc gtcacgccag tctaaccatt gaagataagc
     6781 atacgaattt ggaacaaatt aaggaatttt tacaaaaaga aatcgatccc gatgaaaaaa
     6841 ctctggtatt tatccctaac tgttgggccc tacctctagt ctttaccgtt atcaaagagt
     6901 tgaattataa cttgccacaa gttgggttga ttggttttga caatacggag tggacttgct
     6961 tttcttctcc aagtgtttcg acgctggttc agccctcctt tgaggaagga caacaggcta
     7021 caaagatttt gattgatcag attgaaggcc gcaatcaaga agaaaggcaa caagtcttgg
     7081 attgtagtgt gaattggaaa gagtcgactt tctaaaatga aggaaaatga cttgcagttt
     7141 ctgttaagaa ataaaataat cccacctaga acaagctagg tgggattatt tgcctatgaa
     7201 atgagaaatt atgggagcaa gctcctaaat caactgtttt tgatctactt ctttaactac
     7261 ttgataaaag ttatagaagt aggccaaact tgaaatgatg gttacgacta ggaatattga
     7321 aaatttccat tggacagggt tggttaaaag ttgtggaaag gatatgagga gaaagaagag
     7381 ggctgcgttg aggacaggta tccgttttga ttgtattttc tcaagtcctt tattgagcgc
     7441 aggaagaaag aggagtagga gtagtaaaac tgtatgagaa acagctcctg aaataagggc
     7501 gaagaaaagg aaaatactga taaaaacatg aatgatcagt agtctagcta gtgatttcat
     7561 aaggcacctc ctaatcctgg tcttttttag ctcttgcaat acgaagtgag tcgacaatat
     7621 gtatcatcac tccgaaaaag aaagctccca gtatagtttt aaaaatatgt tttgtattta
     7681 gaagagaact gataaaattt ggattttcac ttgttagggt atcaatgagt ggaattataa
     7741 aaaatatcac tgttccataa atcgaacctg ctttcagacc aggataacgt aattgtttct
     7801 tttctttttt catagtgcac ctcctaatcc tcatcttgat ttttcttagt ttttgcaatg
     7861 cgacgggaga tgaggaactg tatgctcgct ccgaagaaaa tagaaccgag aatgcttgat
     7921 acaccatttc ttatagtgag aagagaatga aaatagtcct gaccttcacc tatgagtatc
     7981 ctgagaagag gagttataaa aaacatccat agaccaaaga acaaacctgc tttcagacct
     8041 gggtaatgta gttgcttact ttctttctcg ctcagcatgt ctggatcaat agctgtaatc
     8101 cctgtttttt tcatttggta ggtgacatag ccagcagcga tgagggcaat cactaaaatc
     8161 agaggaggat agattagagc cacttcttga gggtatttat aggccagaag gagtggaata
     8221 agatttccga aaatcatcag ataaaagagg atgataaaga cttggttccc aatacgatcg
     8281 gcctcacgcc gtttgtattc gtcaagggga ccagaaatac cgtatgtgcg tttgatcagt
     8341 ttttcagtga aggtttcttt tttcatgagt ttgctccttt tttaaaaatc ttcctcccaa
     8401 aagagactgt tgaggtcagt ttggaggctg cgggcgagat tgagacagag ttccaaggtt
     8461 ggattgtact tgtcgttttc aatcatattg atagtctgtc tcgagacacc gatatccttg
     8521 gcgagttcga gctgggaaat acccaattcc ttgcgaaatt ctttcacacg attcatctgt
     8581 tctccttttt gatttatgtc gtatatattt gactttatta tagtctttta aacataaagt
     8641 gtcaagtatt tttgacatat tttttgaaga aatagtagtc tccttgtcct atttgtctga
     8701 caagtgcaag ctggtcggat ttgtggtaaa atagataaga tatgacaaaa gaatttcatc
     8761 atgtaacggt cttactccac gaaacgattg atatgcttga cgtaaaacct gacggtatct
     8821 acgttgatgc gactttgggc ggagcaggac atagcgagta tttattaagt aaattaagtg
     8881 aaaaaggcca tctctatgcc tttgaccagg atcagaatgc cattgacaat gcgcaaaaac
     8941 gcttggcacc ttacattgag aagggaatgg tgacctttat caaggataac ttccgtcatt
     9001 tacaggcacg tttgcgcgaa gctggtgttc aggaaattga tggaatttgt tatgacttgg
     9061 gagtgtctag tcctcaattg gaccagcgtg agcgtggttt ttcttataaa aaagatgcgc
     9121 cactggacat gcggatgaat caggatgcta gtctgacagc ctatgaagtg gttaatcatt
     9181 atgactatca tgatttggct cgtattttct tcaaatacgg tgaggataaa ttctctaaac
     9241 agattgcgcg taagattgag caagcgcgtg aagtgaagcc gattgagaca acgactgagt
     9301 tagcagagat tatcaagttg gtcaaacctg ccaaggaact caagaagaag ggtcatcctg
     9361 ctaagcagat tttccaggct attcgaattg aagtcaatga tgaactggga gcggcagatg
     9421 agtccatcca acaggctatg gatatgttgg ctctggatgg tagaatttca gtgattacct
     9481 ttcattcctt agaagaccgc ttgaccaagc aattgttcaa ggaagcttca acagttgaag
     9541 ttccaaaagg cttgcctttc atcccagatg atctcaagcc caagatggaa ttggtgtccc
     9601 gtaagccaat cttgccaagt gcggaagagt tagaagccaa taaccgctcg cactcagcca
     9661 agttgcgcgt ggccagaaaa attcacaagt aagagggaaa aagatggcag aaaaaatgga
     9721 aaaaacaggt caaatactac agatgcaact taaacggttt tcgcgtgtgg aaaaagcttt
     9781 ttacttttcc attgctgtaa ccactcttat tgtagccatt agtattattt ttatgcagac
     9841 caagctcttg caagtgcaga atgatttgac aaaaatcaat gcgcagatag aggaaaagaa
     9901 gaccgaattg gacgatgcca agcaagaggt caatgaacta ttacgtgcag aacgtttgaa
     9961 agaaattgcc aattcacacg atttgcaatt aaacaatgaa aatattagaa tagcggagta
    10021 agatatgaag tggacaaaaa gagtaatccg ttatgcgacc aaaaatcgga aatcgccggc
    10081 tgaaaacaga cgcagagttg gaaaaagtct gagtttatta tctgtctttg tttttgccat
    10141 ttttttagtc aattttgcgg tcattattgg gacaggcact cgctttggaa cagatttagc
    10201 gaaggaagct aagaaggttc atcaaaccac ccgtacagtt cctgccaaac gtgggactat
    10261 ttatgaccga aatggagtcc cgattgctga ggatgcaacc tcctataatg tctatgcggt
    10321 cattgatgag aactataagt cagcaacggg taagattctt tacgtagaaa aaacacaatt
    10381 taacaaggtt gcagaggtct ttcataagta tctggacatg gaagaatcct atgtaagaga
    10441 gcaactctcg caacctaatc tcaagcaagt ttcctttgga gcaaagggaa atgggattac
    10501 ctatgccaat atgatgtcta tcaaaaaaga attggaagct gcagaggtca aggggattga
    10561 ttttacaacc agtcccaatc gtagttaccc aaacggacaa tttgcttcta gttttatcgg
    10621 tctagctcag ctccatgaaa atgaagatgg aagcaagagc ttgctgggaa cctctggaat
    10681 ggagagttcc ttgaacagta ttcttgcagg gacagacggc attattacct atgaaaagga
    10741 tcgtctgggt aatattgtac ccggaacaga acaagtttcc caacgaacga tggacggtaa
    10801 ggatgtttat acaaccattt ccagccccct ccagtccttt atggaaaccc agatggatgc
    10861 ttttcaagag aaggtaaaag gaaagtacat gacagcgact ttggtcagtg ctaaaacagg
    10921 ggaaattctg gcaacaacgc aacgaccgac ctttgatgca gatacaaaag aaggcattac
    10981 agaggacttt gtttggcgtg atatccttta ccaaagtaac tatgagccag gttccactat
    11041 gaaagtgatg atgttggctg ctgctattga taataatacc tttccaggag gagaagtctt
    11101 taatagtagt gagttaaaaa ttgcagatgc cacgattcga gattgggacg ttaatgaagg
    11161 attgactggt ggcagaacga tgactttttc tcaaggtttt gcacactcaa gtaacgttgg
    11221 gatgaccctc cttgagcaaa agatgggaga tgctacctgg cttgattatc ttaatcgttt
    11281 taaatttgga gttccgaccc gtttcggttt gacggatgag tatgctggtc agcttcctgc
    11341 ggataatatt gtcaacattg cgcaaagctc atttggacaa gggatttcag tgacccagac
    11401 gcaaatgatt cgtgccttta cagctattgc taatgacggt gtcatgctgg agcctaaatt
    11461 tattagtgcc atttatgatc caaatgatca aactgctcgg aaatctcaaa aagaaattgt
    11521 gggaaatcct gtttctaaag atgcagctag tctaactcgg actaacatgg ttttggtagg
    11581 gacggatccg gtttatggaa ccatgtataa ccacagcaca ggcaagccaa ctgtaactgt
    11641 tcctgggcaa aatgtagccc tcaagtctgg tacggctcag attgctgacg agaaaaatgg
    11701 tggttatcta gtcgggttaa ccgactatat tttctcggct gtatcgatga gtccggctga
    11761 aaatcctgat tttatcttgt atgtgacggt ccaacaacct gaacattatt caggtattca
    11821 gttgggagaa tttgccaatc ctatcttgga gcgggcttca gctatgaaag actctctcaa
    11881 tcttcaaaca acagctaagg ctttagagca agtaagtcaa caaagtcctt atcctatgcc
    11941 tagtgtcaag gatatttcac ctggtgattt agcagaagaa ttgcgtcgca atcttgtaca
    12001 acccatcgtt gtgggaacag gaacgaagat taaaaacagt tctgctgaag aagggaagaa
    12061 tcttgccccg aaccagcaag tccttatctt atctgataaa gcagaggagg ttccagatat
    12121 gtatggttgg acaaaggaga ctgctgagac ccttgctaag tggctcaata tagaacttga
    12181 atttcaaggt tcgggctcta ctgtgcagaa gcaagatgtt cgtgctaaca cagctatcaa
    12241 ggacattaaa aaaattacat taactttagg agactaatat gtttatttcc atcagtgctg
    12301 gaattgtgac atttttacta actttagtag aaattccggc ctttatccaa ttttatagaa
    12361 aggcgcaaat tacaggccag cagatgcatg aggatgtcaa acagcatcag gcaaaagctg
    12421 ggactcctac aatgggaggt ttggttttct tgattacttc tgttttggtt gctttctttt
    12481 tcgccctatt tagtagccaa ttcagcaata atgtgggaat gattttgttc atcttggtct
    12541 tgtatggctt ggtcggattt ttagatgact ttctcaaggt ctttcgtaaa atcaatgagg
    12601 ggcttaatcc taagcaaaaa ttagctcttc agcttctagg tggagttatc ttctatcttt
    12661 tctatgagcg cggtggcgat atcctgtctg tctttggtta tccagttcat ttgggatttt
    12721 tctatatttt cttcgctctt ttctggctag tcggtttttc aaacgcagta aacttgacag
    12781 acggtgttga cggtttagct agtatttccg ttgtgattag tttgtctgcc tatggagtta
    12841 ttgcctatgt gcaaggtcag atggatattc ttctagtgat tcttgccatg attggtggtt
    12901 tgctcggttt cttcatcttt aaccataagc ctgccaaggt ctttatgggt gatgtgggaa
    12961 gtttggccct aggtgggatg ctggcagcta tctctatggc tctccaccaa gaatggactc
    13021 tcttgattat cggaattgtg tatgtttttg aaacaacttc tgttatgatg caagtcagtt
    13081 atttcaaact gacaggtggt aaacgtattt tccgtatgac gcctgtacat caccattttg
    13141 agcttggggg attgtctggt aaaggaaatc cttggagcga gtggaaggtt gacttcttct
    13201 tttggggagt gggacttcta gcaagtctcc tgaccctcgc aattttatat ttgatgtaag
    13261 aatggcaccc tgatgtttca gggtgttttt gtgtttaaat acacaatgaa aatcaaagaa
    13321 caatctagaa agctaacttt aggctgctca aaacatagta gtttgaaact agaatagtac
    13381 acctctactt ctaaaatatt gttagaaatc gatttgactg tcctgattga tttgtcctgt
    13441 tcttatttcg ttttaatata cagttttgag atggttgata gaactgacga agtcagctca
    13501 aaacacggtt ttgaggttgt agataaggag aagctgatgt ggtttgaaga ggttttcgaa
    13561 gagtgtaaaa aaatattggt cagttaaagt caaaatcctt gaccttttct gaccaatgta
    13621 gtatattatg aacgtaaggt aaatgaaagc cttactagaa cacttattta aagtaaaata
    13681 gaaagaggtg ggtctatgtt tcatctagaa attttcagaa gtaaagatgg tctactcctg
    13741 cttgaaaaag aaaaaccaga aatagtacgt agggtagcga tctagctagt ctaaattttt
    13801 taaaacaaag gtcaaagata gtcaatatca gtaatcataa ctaagtaaac aaaaagaggt
    13861 aaagaatatg aataacaact ttaataattt taataacatg gatgatttat ttaaccaatt
    13921 gatgggtggt atgcgaggat acagttctga aaatcgccgt tacttaatta atgggcgcga
    13981 agtcacacct gaggaatttg ctcactatcg tacgactggt caattaccag gaaatgcaga
    14041 aactgatgtg caaatgtcac aacaggcatc aggtatgaaa caagacggtg tccttgcaaa
    14101 actaggtcga aacttgacag cagaagcgcg tgagggcaag ttggatcctg ttatcggacg
    14161 aaacaaggaa attcaagaaa catctgaaat cctctcacgc cgcaccaaga acaatcctgt
    14221 tttggtcgga gatgcaggtg ttggtaagac agcagttgtc gaaggtctag cgcaagccat
    14281 tgtgaacgga gatgttcctg ctgctatcaa gaacaaggaa attatttcta ttgatatctc
    14341 aggtcttgag gctggtactc aataccgtgg tagctttgaa gaaaatgtcc aaaacttagt
    14401 caatgaagtg aaagaagcag ggaatattat cctcttcttt gatgaaattc accaaattct
    14461 tggtgctggt agcactggtg gagacagtgg ttctaaaggg cttgcggata ttctcaagcc
    14521 agctctctct cgtggagaat tgacagtgat tggggcaaca actcaagacg aataccgtaa
    14581 caccatcttg aagaatgctg ctcttgctcg tcgtttcaac gaagtgaagg tcaatgctcc
    14641 ttcagcagag aatactttta aaattcttca aggcattcgt gacctctatc aacaacacca
    14701 caatgtcatc ttgccagacg aagtcttgaa agcagcggtg gattattctg ttcaatacat
    14761 tcctcaacgt agcttgccag ataaggctat tgaccttgtc gatgtaacgg ctgctcactt
    14821 ggcggctcaa catccagtaa cagatgtgca tgctgttgaa cgagaaatcg aaacggaaaa
    14881 agacaagcaa gaaaaagcag ttgaagcaga agattttgaa gcagctctaa actataaaac
    14941 acgcattgca gaattggaaa ggaaaatcga aaaccacaca gaagatatga aagtgactgc
    15001 aagtgtcaac gatgtggctg aatctgtgga acgaatgaca ggtatcccag tatcgcaaat
    15061 gggagcttca gatatcgaac gtttgaaaga tatggctcat cgcttgcaag acaaggtgat
    15121 tggtcaagat aaggccgtag aagctgtagc tcgtgctatc cgtcgtaacc gtgctggttt
    15181 tgatgaagga aatcgcccaa tcggcagctt cctctttgta gggtctactg gggttggtaa
    15241 gacggagctt gctaagcaat tggcactcga tatgtttgga acccaggatg cgattatccg
    15301 tttggatatg tctgaataca gtgaccgcac agctgtttct aagctaattg gtacaacagc
    15361 aggctatgtg ggttatgatg acaatagcaa taccttaaca gaacgtgttc gtcgcaatcc
    15421 atactctatc attctcttgg atgaaattga aaaggctgat cctcaagtta ttacccttct
    15481 cctccaagtt ctagatgatg gtcgtttgac agatggtcaa ggaaatacag taaacttcaa
    15541 gaacactgtc attattgcga cctcaaatgc tggatttggc tatgaagcca acttgacaga
    15601 agatgcggat aaaccagaat tgatggaccg attgaacccc ttcttccgtc cagaactcct
    15661 caaccgcttt aatgcagtca tcgagttctc acacttgact aaggaagacc tttctaagat
    15721 tgtagatttg atgttggctg aagttaacca aaccttggct aagaaagaca ttgacttggt
    15781 agtcagtcaa gcggctaaag attatatcac agaagaaggt tacgacgaag tcatgggggt
    15841 tcgtcctctc cgtcgagtgg ttgaacaaga aattcgtgat aaggtgacag acttccactt
    15901 agatcattta gatgctaaac atctggaagc agatatggaa gatggcgttt tggttattcg
    15961 tgagaaagcc taagatagaa ttttgaggat aaaaaagaag gagccagctg aaaaaaactg
    16021 gttccttttg aggtacgacg ggcatgtcgt acagtaggtt gaaactagaa tagtacacat
    16081 ctacttctaa aatattgtta gaaatcgatt tgactgtcct gattgatttg tcctgttctt
    16141 atttcatttt actatatatc tgaggtgtaa gtcctcggtg ggtacctgct accggtgctc
    16201 ccaatagtga ttcccaagcc tgactatcgt gaggtagcgg attaaaacgg tctggggata
    16261 gaccgtttta agtctgacgc tggaaataag aatcgtcaga ggaagggata gcgaaatcgt
    16321 ggctctacga ataggaacgt gataataagg cgtatatagc ggataagggg cctcaaactc
    16381 taaagttcaa aaaggtagtc gtaacctata tgcgtaaatc acgagagcaa ctgaatttgt
    16441 ccattcgagg atggataaac tatttttcat tggaaaatat gaaaagtata gtcactagca
    16501 tagatgagcg cttgcgtact cgcctacgag tgattatctg gaagcaatgg aagaagaaat
    16561 ctagacgatt atggagattg cttaagttag gggttcctaa atggatagca gataaggtat
    16621 ctggctgggg tgaccactat caattagtat ctcagaagtc ggtacttaaa cgtgctatat
    16681 caaaaccagt ccttgagaaa cgtggactgg tttcgtgttt ggattattac cttgaacgac
    16741 atacgttaaa agttagttga accgccgtat gccgaacggc acgtacggtg gtgtgagaag
    16801 ggctagagat tatcccctac tcgattttaa atcacatgac gttcaaaggc atcatctgaa
    16861 atcccttgtt ccaagatgag ttttgcccat tctttagcag agaagaggct gtggtccttg
    16921 tagtttccgc aagattcgat ggttgtccct gggacctctt cccaagtagt agtttcagcg
    16981 atttccttga gcgaatcctt gataacagct gcgattttag cactggtgtg acgtccccac
    17041 ataatcatgt ggaagcctgt gcggcaacca aatggcgaac agtcaatcat gccgtcaatg
    17101 cgggtacgga tgagtttggc taagaggtgc tcgatagtgt gaaggccggc agtagggata
    17161 gagtcttcgt ttggttgcac caagcgaata tcataattgg agatgatgtc tccttttggt
    17221 cctgtttctt ccccaatcaa gcgaacatag ggtgctttga caatggtgtg gtcaagttca
    17281 aaactttcga caataacttc ttttgacatg gtaaatcctt tcagttttct tctctcatta
    17341 tatcataaag gttgctcctg agacagagag aaaacctctc cgaggctgga gaggttgaaa
    17401 tctttactta cgatataagc ggtcgtattg gtagtatggg tcaaaggtta cgttgatacc
    17461 cagtttacga aggacattct tgtcttcatc agtcaagatg atggttgagt gggcttcgct
    17521 tcctttgagg ttgccgagtt cttccatagc gcgggtagca tcaggatttt ctgtagctgt
    17581 gatagcaagt gcaatcagga tttcatttga atgaaggcgt ggattgcggc taccgagatg
    17641 atcgatttta agaccttgga ttggcttaac aacttcaggc tcgattagtt ttacttcttt
    17701 agcgatgtca gctgattttt tgatggcgtt gatcaaggca gcggctgtag ggccaaagag
    17761 ttctgagttc ttaccagtga cgatttcccc atttggcaat tcaaaggcta gggctggtcc
    17821 accagtttct tctgcttttt ggcgcgcaac gacagcaacc ttacggtctg caggtgtgat
    17881 accgaggtcg ttcatgagca actcaatttt cttgacggca gcttcgccaa ctttttcagc
    17941 tttgaagtca agaactgttt gatagtaacg gcggatgatt tcttgtttag aagcttcgac
    18001 agcggcctcg tcatctgtaa tagcgaaacc aaccatgttg acacccatat ctgtcggtga
    18061 agcgtatggt gattttccga gaatacgttc caacatgcgt ttgagcactg ggaagatttc
    18121 gatatcacgg ttgtagttga cagtggtttc tccataggtt tggagatgga aggggtcaat
    18181 catgttgaca tcatcaaggt cagctgtggc agcttcataa gccaagttaa ctggatgatg
    18241 aaggggaaga ttccaaacag ggaaggtttc aaatttagcg tagccagatt tgatgccatt
    18301 gatttggtcg tggtacatat tggacataca cgttgccaat tttccagaac cgggtccagg
    18361 agcggttacg acaatcaagt tgcgaccggt tttgatgtag tcgtttttgc ccatgccttc
    18421 tggggaaatg atgtgatcca tatccgtagg atatcctttg attggataat gaagataaga
    18481 atcaattccg tttttctcaa gttggttgcg gaaggcatct gcagcgggtt ggccagcgta
    18541 ttgtgtaatg acaacggaac caacaaaaat ccctaattca ttgaatttgt caatcaaacg
    18601 aagaacttct tggtcataag aaatgcctaa gtcgccacgt gctttggaat gttcaatgtt
    18661 gctagcatta atggcaatca caacctcaac ctgctctttc aattcttgca agagcttgat
    18721 tttgttgtca ggttcataac caggaaggac acgagcagcg tggaaatctt ctaacatttt
    18781 accgccaaac tctaagtaga gcttgccgtc aaattggtta atgcgctcca aaatatggtc
    18841 gcgttgtaaa ttcaaatact gttcagaact aaaagcttgt tttttcattt ttttacctct
    18901 ggactctatt ataataaaaa attggaagtt aggaaactac ggagctaaaa aagaaattaa
    18961 aaagattaag caaacgcttg cacaaaattt taaaaagtgc tatcatatac tatagattat
    19021 taaaataatg aggtaaacag atgcaagaaa aatggtggca taatgccgta gtctatcaag
    19081 tctatccaaa gagttttatg gatagtaatg gagatggagt tggtgatttg ccaggtatta
    19141 ccagtaagtt ggactatcta gctaagttag gaatcacagc gatttggctt tctcccgttt
    19201 atgacagccc tatggatgat aatggctacg atattgctga ttatcaagcg attgcaacga
    19261 tttttggaac catggaggat atggatcaac tgattgcgga agctaagaag cgtgacattc
    19321 gcatcatcat ggacttggtg gttaatcata cctcagatga acatgcttgg tttgtcgaag
    19381 cctgtgaaaa tactgatagc cctgagcgag actactatat ctggcgcgat gaacccaatg
    19441 acctagattc tatctttagt gggtctgctt gggaatacga tgaaaagtca ggtcaatact
    19501 atctccactt tttcagcaag aaacagccgg atctcaactg ggaaaatgaa aaacttcgcc
    19561 agaaaattta tgagatgatg aacttctgga ttgataaagg tattggtggt ttccgtatgg
    19621 atgttattga catgattggc aaaattcctg acgagaaggt agtcaataat ggtcctatgc
    19681 tccatcccta tctcaaggaa atgaatcagg cgacctttgg agctaaggat ctcttgacag
    19741 taggggagac ttggggagca acgccagaga ttgccaagct ctactctgat ccaaaggggc
    19801 aagaattgtc tatggtcttc cagtttgaac atatcggtct tcagtatcag gaaggtcagc
    19861 ctaaatggca ctatcaaaaa gagctgaata tcgctaagtt aaaagaaatc ttcaacaaat
    19921 ggcagacaga gttaggagtt gaggacggct ggaattccct cttctggaac aaccatgacc
    19981 tccctcgtat tgtctcaatc tggggaaatg accaagaata ccgcgaaaaa tctgccaaag
    20041 cctttgcaat cttacttcat ctcatgagag gaactcctta tatctaccaa ggtgaggaga
    20101 ttgggatgac caactatccg tttgaaacac tggatcaagt agaagatatt gaatctctca
    20161 actatgcgcg tgaggctctt gaaaaaggtg ttccgattga agaaatcatg gacagtatcc
    20221 gtgttattgg acgtgacaat gcccgtaccc ctatgcaatg ggacgagagc aaaaacgctg
    20281 gtttctcaac aggtcaacct tggttggcgg ttaatccaaa ttacgagatg atcaatgtcc
    20341 aagaagcgct ggcaaatcca gattctattt tttataccta tcagaaactg gtccaaattc
    20401 gcaaggagaa tagctggcta gttcgagctg actttgaatt gcttgatacg gctgataagg
    20461 tctttgctta tatacgtaag gatggcgacc gtcgcttcct agttgtggct aacttgtcca
    20521 atgaagagca agacttgaca gtagaaggaa aagtcaaatc tgtcttgatt gaaaacactg
    20581 cggctaaaga agtacttgaa aaacaggtct tggctccatg ggatgctttc tgtgtggaaa
    20641 tgactgacta gaatgagcaa acctcaagtt tttgaagctt gaggtttttt actatagtgg
    20701 attgaaacta gaatagtgca cctctacttc taaaacattg ttagaaatcg atttgactgt
    20761 cctgactaat ttgtcctatt cttatttcat tttactatat ttgtagttga ggagaattaa
    20821 gctcctcact agtaaactct tcataatcct ttttattttt atgaagatat tgtttgaaag
    20881 atgtgagttt ccacggatgg gtttgtggag ggatatactt gcgtctttct ttttttgttc
    20941 tggttcttgt tcaaagtttt tcgagtagag ttcatgatct agtagctcct ttgtgtgata
    21001 gattttgtca gcgatattga ggtagatgtc tccgtcaaat gcttttataa ctaatgcttt
    21061 cgtatttctg atgaaataga cttcttttcc ttgttcggta gggatatagt aacgattttg
    21121 gaatcggata tggtgtccac tatcgacgac tctctccgcc agtctggcca gaatgagatt
    21181 cctttcagag gggttaggaa cctcctcgaa gacagagagt tttgtcttgt ttccaaactg
    21241 ttcattaaag gtttggatgt aggaaagcag gaaggtattg gcttcttcca aggtatgaat
    21301 attgtttcgt tccagttcga taggcaggcg agattgtagt gtctgattaa gtctttcgac
    21361 tctcccttta gcttgaggga tagaggttgt ctccagaaga atccctagtt ggtgacaggc
    21421 gtatccaaat tgtgtatggg tgtcgtcctc cattttcttc gagttggagg cttgatatag
    21481 gtaaagaccg ttctcttatc tgttttaatt tgaaggggaa cgccgtgatt gcctaaaatt
    21541 tgttcgagga catgatagta agcattcaag gtctcttgtt tatcaaaata agcgcctagg
    21601 atattgccag aagcatcatc aatggctaag tgtaagttag atgtttgggc tccaaaccat
    21661 gcatgagggc tggcatccat ttgaatgagt tctccagcaa atttctttct gggtctacta
    21721 ggatgtactt ttttaggggc ttcaaggaag ttttcagccg tcggtaagat tggattgtct
    21781 aggggttgat tcaggttcag tttagcttgt tttcttactc tcttctttgt ctttctatgg
    21841 gacttaggcg acaggatatt tttcttatag agtatttttc taacagttgt atcagagagc
    21901 tgaattcctt cttcttcagc tagcaattca cagaaatgaa ggacatttgg tttatatgtt
    21961 tcataggaga ggtatttctt taggagacgt tctttgattt catcagggat tgcatgtttt
    22021 ggttttcgat ttctgtttcc gtgtctgaag gcttcttttc ctttcagttg ataggctagt
    22081 agcagacgat tgatttgtct ttcagaaaga ttgagctcga cacaggttcg tttctttgtt
    22141 ttctttcctt gcgctatagc ttttatcaca agatattttt tagtttcatt catattcagt
    22201 tggatccttt tcatatgact attctaccaa atgggacatt ttcacgttcg atttactaaa
    22261 gacattatca cattcgaatt acacaagatg cagatagtga aaataaaggt gtagacatta
    22321 ccgtaaaaaa gtgatataat cgtatgatgt tcaaggtata ggtgttaatc atgagtagac
    22381 gttttaaaaa atcaggttca cagaaagtga agcgaagtgt taatatcgtt ttgctgacta
    22441 tttatttatt attagtttgt tttttattgt tcttaatctt taagtacaat atccttgctt
    22501 ttagatatct taatctagtg gtaactgcgt tagtcctact agttgccttg gtagggctac
    22561 tcttgattat ctataaaaaa gctgaaaaat ttactatttt tctgttgctg ttctctatcc
    22621 ttgtcagctc tgtgtcgctc tttgcagtac agcagtttgt tggactgacc aatcgtttaa
    22681 atgcgacttc taattactca gaatattcaa tcagtgtcgc tgttttagca gatagtgata
    22741 tcgaaaatgt tacgcaactg acgagtgtga cagcaccgac tgggactgat aatgaaaata
    22801 ttcaaaaact actagctgat atcaagtcaa gtcagaatac cgatttgacg gtcaaccaga
    22861 gttcgtctta cttggcagct tacaagagtt tgattgcagg ggagactaag gccattgtcc
    22921 taaatagtgt ctttgaaaac atcatcgagt cagagtatcc agactacgca tcgaagataa
    22981 agaagattta taccaaggga ttcactaaaa aagtagaagc tcctaagacg tctaagaatc
    23041 agtctttcaa tatctatgtt agtggaattg acacctatgg ccctattagt tcggtgtcgc
    23101 gatcagatgt caatatcctg atgactgtca atcgagatac caagaaaatc ctcttgacca
    23161 caacgccacg tgatgcctat gtaccaatcg cagatggtgg aaataatcaa aaagataaat
    23221 taacccatgc gggcatttat ggagttgatt cgtccattca caccttagaa aatctctatg
    23281 aagtggatat caattactat gtgcgattga acttcacttc gtttttgaaa ttgattgatt
    23341 tgttgggtgg aattgatgtt tataatgatc aagaatttac tgcccatacg aatggaaagt
    23401 attaccctgc aggcaatgtt catcttgatt cagaacaggc tctcggtttt gttcgtgagc
    23461 gctactcact agcagatggc gatcgtgacc gtgggcgcaa tcaacaaaag gtcattgtgg
    23521 ctatccttca aaaattaacg tcaaccgaag cgctgaaaaa ttatagtacg atcattaata
    23581 gcttgcaaga ttctatccaa acaaatatgc cacttgagac tatgatagat ttagtgaata
    23641 ctcagttgga aagtggaggg aagtataaag taaattctca agatttaaaa ggtacaggtc
    23701 ggatggatct tccttcttat gcaatgccag acagtaacct ctatgtgatg gaaatagatg
    23761 atagtagttt agctgtagtt aaagcagcta tacaggatgt gatggagggt agatgaaatg
    23821 atagatatcc attcgcacat cgtctttgat gtagatgatg gtcccaagtc aagggaggaa
    23881 agcaaggctc tcttggtaga atcctacaga cagggggtgc gaaccattgt ctctacctct
    23941 caccgtcgca agggcatgtt tgaaactccg gaagagaaga tagcagaaaa ctttcttcag
    24001 gttcgggaaa tagctaagga agtggcgagt gacttggtca ttgcttacgg ggctgaaatt
    24061 tactacacac cagatgttct ggataagctg gaaaaaaagc ggattccgac cctcaatgat
    24121 agtcgttatg ccttgataga gtttagtatg aacattcctt atcgcgatat tcatagcgct
    24181 ttgagcaaga tcttgatgtt gggaattact ccagtcattg cccacatcga gcgctatgat
    24241 gctcttgaaa ataatgaaaa acgcgttcgg gaactgatcg atatgggctg ttacacgcaa
    24301 gtaaatagtt cacatgtcct caaacccaaa ctttttggcg aacgttataa attcatgaaa
    24361 aaaagagttc agtatttttt ggaacgtgat ttagttcatg tagttgcaag tgacatgcac
    24421 aatttagaca gtagacctcc atatatgcaa caggcatatg atatcattgc taagaaatat
    24481 ggagcgaaaa aagcgaaaga attttttgta gataatccca gaaaaattat aatggatcaa
    24541 ttaatttagg agaaaatatg aaggaacaaa acactttgga aatcgatgta ttgcaactat
    24601 tcagggcttt atggaaaaga aagttggtca ttttattagt ggcaattata acttcttcag
    24661 ttgcttttgc ctacagtact tttgttatca aacctgagtt tactagtacg actcggattt
    24721 atgtagttaa ccgtaatcag gaagagaagt ctggtttaac caatcaagac ttgcaggcag
    24781 gatcatactt ggttaaagac tatcgtgaaa ttatcctatc gcaggatgtt ttggaggaag
    24841 ttatttctga tttgaaacta gatttgacgc caaaaggttt ggctaataaa attaaagtaa
    24901 cagtaccagt tgatacccgt attgtctctg tctcagttaa tgatcgagtt cctgaagagg
    24961 caagccgtat cgctaactct ttgagagaag tagctgctca aaaaattatc agtattactc
    25021 gtgtttctga tgtgacaaca ctggaggagg caagaccggc gatatcacca tcttcgccaa
    25081 atattaaacg caatacacta attggttttt tggcaggggg gattggaact agtgttatag
    25141 ttcttcttct tgaacttttg gacactcatg tgaaacgtcc ggaagatatc gaagatacac
    25201 tgcagatgac acttttggga gttgtaccaa acttgagtaa gttgaaatag gagagaggaa
    25261 tgccgacatt agaaatagca caaaaaaaac tggagttcat taagaaggca gaagaatatt
    25321 acaatgcctt gtgtacaaat atacagttga gcggagataa actaaaagta atttccgtta
    25381 cttctgttaa ccctggggaa ggaaaaacaa ctacttccgt aaatatagca aggtcgtttg
    25441 cgcgtacagg ctataaaact cttttgattg atggcgatac tcgaaattca gttatatcag
    25501 gagtttttaa atcgcgtgaa aaaattacag ggctaacaga atttttatct gggacagctg
    25561 atttatctca cggtttatgt gatacaaata ttgaaaattt atttgtaatt caatcgggat
    25621 ctgtatcacc aaaccctaca gccttgttac aaagtaaaaa ttttaatgat atgattgaaa
    25681 cattgcgtaa atattttgat tatatcattg ttgatacacc acctattgga attgttattg
    25741 atgcggcaat tatcactcaa aagtgtgatg cgtccatctt ggtaacagca ataggtgagg
    25801 tgaataaacg tgatgtccaa aaagcgaaac aacaattaga acaaacagag aaactgttcc
    25861 taggagttgt tttaaataaa ttggatatct cggttgataa gtatggagtt tacggttcct
    25921 atggaaatta taggaaggaa taacggagta attgataaaa atgtattttg tttttaaaaa
    25981 tattttagat agatttttgg cgtttttcct atttatcaca ctgataatca taccgattat
    26041 tccgataaca attctggtta tttggataga agatccagga gatgtgtttt tctttcaaga
    26101 tagaattggt ttaaatggga agagctttaa agtaataaag tttcggagca tgtataaaga
    26161 tgctgatcaa aggataaaga aaagtattat tagtggtgaa attgatcgtc taaattttaa
    26221 agaacattct caaagtatga ctacaaaagt cggtaaagtg atacgaaaac tttcaattga
    26281 tgaattacct caattagtga atattataaa aggtgatatg gctatagtgg gacctcgtcc
    26341 attacaacaa tttgaaataa ctcatcatat tcttacccat aaagaaatgg agactacttt
    26401 aaagatgtct aaaagattgt ctgtgaaacc tggtttgctt tgttattggc aagttacgcc
    26461 gaataaaaat gacattcctt ttagtgatag aatgaatcta gatttattat acattgataa
    26521 tgtatctttc aagactgatt tcttgcttat tttgaaggga ttttatacag ttttaatggg
    26581 taataacaat taacatgaaa aatataaaaa tattagtagc aacacataaa aaatataaaa
    26641 tgcccagtga ttcaaatatg tatctaccaa ttcatgtagg atgtgaagga aagaaaaatt
    26701 taggatttca aggtgacaat tcagaagaaa atatttctaa tttaaatcct tattattgtg
    26761 aattaactgg cttgttttgg gcttggaaaa acttagattg tgattatctg ggtttagtac
    26821 attatcgtcg ttattttact aaaatgacaa aaaggtacaa tgaatcaata aatatcgatg
    26881 atgtaatttt aaataggttt gaagttgaga aattgttaga gaactcagat atcattgttc
    26941 ctaaaagaag aaaatattat attgaaactc tttattctca ttacgaccat acttttgatg
    27001 gttctcattt agatctagct agaaaaatga ttgaaatgaa gaatccagaa tatctctcta
    27061 gttttgataa ggtaatggaa caaagaagcg ggtacatgtt taacatgttc attatgaaaa
    27121 aagaactggc agacgattat ttttcttggc tgtttcctat cttggatagt atgtatgaaa
    27181 gtatggattt atcagggtta actgattttg aagctagatt atttggaaga gtaagtgagt
    27241 tgttatttaa cgtatggttg gtgaagagca atttaactcc aaaggaagtg ccgtttatgt
    27301 atatggaaaa agttaactta tttaaaaaag ggatttcatt tttgatggcg aaatttttcg
    27361 gaaagaaata tggacagagt ttttagttag gaataaaaaa tagtgatgaa agtagtaata
    27421 aaaagaaagt ctttgccaga gattttagct cttagtgcac taactatatt tttagttgtg
    27481 tcaattttag atgtgacttt ttatgttcag tatcttccaa aagttgttta taagatactg
    27541 atagctattt cgcttattct gctagttata aaagagttgt acaaaagaaa gtttgattat
    27601 agaactatca taagtctatt tgctacagtt ttgatgtatc tccttatagg gagggtgagt
    27661 actcttaact ctaatattgc aataggaatt attttcattt atgctttacg cgatattcct
    27721 tttaaaagcg tggcaaaaac ttctttagca gtaagtgtac tcatattact gtttgttata
    27781 actagcgcaa aattgggagt tattataaat tatttagaga tttctgggac tcgagtccgt
    27841 agttatttag gatttaggta cgcactattc ccatctatct tgatgatgaa catagtcgct
    27901 attgtatttt atttaaagca aaataaaata caatattggc aatggttatt gttatcttta
    27961 tctgcttatt ggctgtatga tgaaacggat tctcgattaa cattttatag ttcctgtata
    28021 ttgttgatat gcagtttatt aataagatgg atcccagaac tattctctaa gttcggatat
    28081 atatttaaag cttttaaact cacctttatt ataaatgcag ttgttagttt ttgggtctcc
    28141 tttacctatc tcaatttgag tcattcttat atcaataatc tttttttaaa attagactat
    28201 atattaggtg gtcgtatata cttgatgaat aaatcgttga atttgtatgg ttttggatta
    28261 ttcggacgac cagttgaatg gaatggaaat ggtctgacca ttgaaggagt tagaaactat
    28321 cagacctatc tgtatgttga taatttgtat gttcaaattt tacaaaaatt tggtttactc
    28381 gctctaggaa taatgctcct agtcctaact ttaaccttgt ttaaagtgat taagagacgc
    28441 gaatgggttc tgtcttttat tttgatattg atgagttttc attccatgat tgatgatttg
    28501 aatttgtacc ttcattacaa tattttttgg atattattag gtagtttaat ctaccccgat
    28561 tatcaatttt ctgatgaaag tgatgaagag ttaggggaaa attcttttga agaaattata
    28621 tagtgaaatg ctaagaaata tttgagaaga actcacaaga gtatagctga gaagacagtt
    28681 gtatatcgag ttttgctgtt tttatatagg agggaagtat gtcggatata aaaatcattc
    28741 aagataagat tttaattatc ttaaaagagt ttattagtat ttgtgaagaa aataacctga
    28801 cctactatgc tctaggtggg accttgttgg gcgcggtacg tcataaagga ttcatacctt
    28861 gggatgacga tattgatatc ggtatgccaa gagaagatta tgaaaagttt aaaatactag
    28921 ccccagacct gttaccaagt aatttaaaaa tagttaataa tccacttaat cttgatataa
    28981 ctcagttagt agataaaaat gttattgtta aaattgcgaa ttcggaaaac aatgtgttta
    29041 ttgacatttt tcctctagat ggttatccag aaaaaggatt ttttgcagct aaattgcata
    29101 gttttaggct attgtttcaa agaatgcttt gtaaaatatc agttttagac cagcttgaag
    29161 ataaagaccg tggcactgtg gagaatctta tagttaaaat atcgaaaatg ctaagaatcc
    29221 aaaaagtact tcctaaggat acattggtag aaaatctgca taaagttatt caaaaatatg
    29281 attttaaaac ttctcgttac gtcggtaatg ttctaggtag atatagggag agagaaatag
    29341 ttccgaaaga gtattttaaa gaacctgttt ctcttatttt tgaggatacg atgataaact
    29401 gtccgacaaa gtacaaggaa tatttaagcg aaatctacgg tgattacatg aaattaccat
    29461 cagtagaaga tagagtagca cataatatag aacttatatc agtaggtgat gcagagtgaa
    29521 gggtaggata gaaattggga aaaaaaatat gtattgtgaa atggattttg gatgattctg
    29581 gtggcggtga gcgagttgct gtatctttgg caaacgaact tacaaaaaag tatgaagttc
    29641 atttaattgg aattacaaca aagcaatcgg acctgttctt taaaatcaat tcccaagtaa
    29701 gatactccaa tttttttgac catagagtac gcttgtctaa gaatattcta aaaatctcaa
    29761 aaatgttaag aaaatatttc atagataatg aaatagaggt tggttttggg atagggatat
    29821 ctgctaatgt atttttatct ttggcaggaa taggaactca aactaaagta gttttgtgtg
    29881 atcataccaa ttcgattacg gataatagag aattttctca gaaattccaa agatatgttg
    29941 ggacaaagtt ggcagacaag attatcactc tcactcaaga agaccgtgaa aattatataa
    30001 aaaaatacgg tgttcctgag gaaagaattt gctacatcta taattggaaa gaggctgctc
    30061 tttcagatgt atcttataat aaaaaatcaa ctaaaattgt gactgttggc cgttttgatt
    30121 atcaaaaagg ctatgattat ctcattcaag tcgcgaaaaa agtgttagag aaaagggctg
    30181 actggacttg ggaaatctac ggttccggca atcaagatga agtagagaaa atcagagatt
    30241 taatcaacga aaatgattta caggataggt tagtcataaa aggactcgaa aaaaatcaag
    30301 atttgattta tggagataaa gggatttatg tcatgacttc tcgctatgaa ggtctacctt
    30361 tagtcctgct ggaagcacaa caatataatc ttcctatagc tagctttagt tgtccgacag
    30421 gaccgaacga aattgttgaa gatggagtta atggctatct ggttgagtgt tatgatgtag
    30481 aagcgatgtc taatagatta ttagaactaa tgaatgataa ggagctaaga aatcgttttt
    30541 catctcatgc aaaagataac attgaaaaat ttaataaaga ccgaattata catcagtgga
    30601 tagatttgat agaagaagta tctggggggg ggaaatgtct aataaaatac tgacgattac
    30661 tgtgccaacc tataatattg aaaactatat tggtaaatgc atagaatcat ttaaagctgt
    30721 aaatcctacc tattacagtg attttgaagt gttaatcatt aatgacggaa gtactgataa
    30781 ttctgtacaa gttgttaagg atttaatgga aggtagcact ttagatttaa gaattatcac
    30841 aaaagaaaat gggggccatg gctcaactat taatcgcggg attaaagaag ctagtggaaa
    30901 atattttaag gtcattgatg gggatgattg gatcaatgtt ccagaatttg aaagcttatt
    30961 ggataagtta agagagatta acactgattt agtgatttct gactatacag agcagcatgt
    31021 atataataat agcactattt ttaaagaatt ctcttcttat ctaattccaa atcaagagac
    31081 aagaggtatt cctagcaagt ggacacctat gcatgccctg gtctataaaa caagtatctt
    31141 gaaggataat gctattacga ttagtgaaaa tacattttat gtcgaccaag agtatacaat
    31201 gctccctctt caatttgtag aaaattatat ttattttaag ttggatattt atcagtactt
    31261 cttgggaaga gctgatcaga gtatgaatat tgatataatg agaaagagag cagatcatca
    31321 tgagagagta acgaaacgaa tcttagactt atataaagag agttatacac aaaagccaga
    31381 aatagaaaag gttgtcagtg actctttgca gtatctggtt aataagcaaa atattttgta
    31441 tgttatgaat gaggaacttg ataaggtata tgaactgttt tcatattctg agaaaagtgg
    31501 attcaaattt aaatttgaaa caaaaacaaa gacttcaaat ttactttatg tcaattataa
    31561 aacgaagtat ctttttaacc ttgttattaa aaatctagtt aaaagaaaag caaacagtct
    31621 agaaaaagaa tttcaagaga agggattttg atgaaatatg tcaggaagta aaacaaatca
    31681 tcaatttttt ctgaaggaat tcataacaaa attaactaca ctgtataaga ctgtattcaa
    31741 gtggagtgtg cttgtatgaa agtacttaaa aactacgctt acaatctttc atatcagtta
    31801 ctaatcataa tcttaccgat tattaccact ccctacgtta ctaggatttt tagttcggat
    31861 aatctaggga cttatggtta ttttaactca attgtaacct attttctttt gctggctact
    31921 ttaggaatag gaaattatgg aacaaaagag atttcaggta ataggaaagc tatccatcag
    31981 aatttttggg gtatttatag tatacaactg ggagcatctc tattctccac tttcctttat
    32041 gttattgtct gtctaatttt accagctatg caaaatactg tagcctatat tttaggctta
    32101 agtttgtttt ctaaaggttt agatatttct tggttatttc aaggtttaga ggattttcgg
    32161 aaaattacag taagaaatat aactgtgaaa gtcattgggg taacctcgat tttcttattt
    32221 gtaaaatcag ctagcgacct ctacctttat gtttttcttt taacgatatt tgagttatta
    32281 gggcaactta gtatgtgggt accagctcgg gaatttattg ggaaaccgca ctttgactgg
    32341 ttgtatgcta aacaacattt gaagccagtt atcttattat ttttaccaca ggtcgctata
    32401 tcgctttatg tgactttaga tagtactatg cttggttctc tagcctcaat aagagatgtt
    32461 ggaatttatg atcaatctct gaaacttgtc aaaatattat taacattagt aacttcatta
    32521 ggaagtgtca tgttgcctag agtttcaaat cttttatcct caggggatca taaagcagtc
    32581 aacaaaatgc atgagatatc atttttaatt tataatttgg ttattttccc cattatggca
    32641 ggaatgctaa ttgtaaatga tgactttgta acctttttcc tcgggcaaga ttttcaagag
    32701 gcacgttatg cgatagcaat tatgattttt agaatgttct ttattggttg gaccaatatt
    32761 atggggattc aaattttgat acctcataat aaaaataaag aatttatgct gtcaacaata
    32821 attcctgcta ttgttagtgt aggcttaaat cttctcttgc ttccaaagct gggctatata
    32881 ggagcagcaa ttgtttctgt cttaacagag gcgctagtat gggctattca attgtactat
    32941 actcgtacat acttaaaaga tgttctgatt attagaacta tgataaaaat tattctagcc
    33001 tcagctatca tgtatagcgt tttgctagtt tctaagacat acatacattt ttccccaact
    33061 ataaatgttt tggtatttgt ggtgttaggt ggaatcattt atcttttttc agttttatct
    33121 ctaaaagtga tagatgtgat agaattaaaa caagtaatta ggaaaaatta gaatgcataa
    33181 atttaaagat attaacttgg atttactaaa agtaattgca tgtgttggag ttgttttact
    33241 ccatacagag atggggggat ttaaagagac aggttcatgg aatttttcga catatttata
    33301 ctacttagga acctattcta tccctctatt ttttatagtt aatggttatt tattgttagg
    33361 gaagaaagag attacctatt cctacatatt acagaaagta aaatggattc taataacagt
    33421 gctgtcatgg acccttatag tttggctatt taaacgggat ttttcagtta atccaataaa
    33481 aaaacttata ggatcattgg tgcaaaaagg ttatttcttt cagttttggt tttttggtgc
    33541 gcttatactt atttatatat gtctccccgt tttgaaacaa tttcttaatt caaaaagaag
    33601 ttatttatac tttttatctg tattgctagt tattggtttg atttttgagt taacaaatat
    33661 tgtgcttcaa atgccaatac aagcatatgt aatacaaact tttagattat ggacttggct
    33721 tttctattat attttagggg gctttatatc tcagtttgat aaaaatacca tcaaaaatgg
    33781 gtttaagaga tggatgaaag taattgcagt acttttatta ttagt
//
LOCUS       DAVLTT010000018        32667 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLTT010000018 DAVLTT010000000
VERSION     DAVLTT010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.018"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(<1..1532)
                     /locus_tag="VYN15_000933"
     CDS             complement(<1..1532)
                     /locus_tag="VYN15_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1452277.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKEIMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEHNDHLEITAYHISDDVMQRSITQMS
                     VTSQSCGMALSRMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSVLLDGKHSIVGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKNYQRTKNSQNVVTRIHAKSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKSVEELQKWAQAKFSNEGIDKISDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDVFKKAIAYEFDALKEEYISLILDDKAGAGG
                     SRTSGGLSSAADAILGVTESAQEVALEKALQNADLDFDHKAGLLRQEISDGIELAKAK
                     AEEVKQELSDTINQRFNSFDNGPLKEAKRRAEEALRNAGASSLLAQEAKRIGLDSVAR
                     LEEFKSQTTSAQTALSGDLDALKRTIVNDIRPKQAQVEAEIAKQVEALVQTKKELSGA
                     STL"
     gene            complement(1533..2255)
                     /locus_tag="VYN15_000934"
     CDS             complement(1533..2255)
                     /locus_tag="VYN15_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1452278.1"
                     /translation="MIKHNELVIDGVRTSSFPFKVIVHDSPSIALGESKTALLEHGGI
                     SGAIVQTNKHRELVKKSYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVTDLEEVQPGLYMTKATFTCHPTKYFKATDTQRLTRSGTLNVQGSALAFPKITIVG
                     QSVVETSFTIAGQVIRLEKLSESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            complement(2252..5011)
                     /locus_tag="VYN15_000935"
     CDS             complement(2252..5011)
                     /locus_tag="VYN15_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEV1452279.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALNENGSATQNNKNQLKELQNEQSQLASEMSKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANRM
                     EAELNQAKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAEALDLTSRATRAAADGAAFYDKSIESVTESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFSSLPAPVKDFVVILGTV
                     VTAVGVIAPIFLSLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILEVINAVVSEISNFVMSIFGTVVAWWTENQELIRASAETVWN
                     AIYTVISTILEILGPLIQAGWDNIQLVITTAWEIIKTVVETAINVVLGIIQAVMQIIN
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNIWNSIKDTV
                     SNVLNAISSTVSSVWEGIKSTISSAINGARDAVSSAIEAIKGLFNFNISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADISRIADEVAQRIADELQRKTQL
                     RAGVT"
     gene            complement(5289..5708)
                     /locus_tag="VYN15_000936"
     CDS             complement(5289..5708)
                     /locus_tag="VYN15_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452280.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATNIDISMLSDFDMTFFNRLFWTFAKSENPHIKPYEQFFMEME
                     VFPIQEVGPVLMEMLNASMTTKKHQMNQNQLAKKSSQ"
     gene            complement(5720..6298)
                     /locus_tag="VYN15_000937"
     CDS             complement(5720..6298)
                     /locus_tag="VYN15_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1452281.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAIDLTL
                     DTKGETTTIKADNKDYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAMMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVAA"
     gene            complement(6310..6633)
                     /locus_tag="VYN15_000938"
     CDS             complement(6310..6633)
                     /locus_tag="VYN15_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452282.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPNLPYLVYYESIPAINA
                     ADNTVNHQIKSVTVELAFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            complement(6630..6989)
                     /locus_tag="VYN15_000939"
     CDS             complement(6630..6989)
                     /locus_tag="VYN15_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV1452283.1"
                     /translation="MSLTSDLANEIAKAMAEYSAEVEDKIDLIAEDVVNEAVTELKAT
                     SPKRHGKYARNWRFKKNAKGSYVIYNAAPTYRLTHLLENGHVLRNGGRSRAFPHIKPV
                     EEKVKENFEKRIKEIGK"
     gene            complement(6986..7285)
                     /locus_tag="VYN15_000940"
     CDS             complement(6986..7285)
                     /locus_tag="VYN15_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEV1452284.1"
                     /translation="MWNHEITLISKEVTGKDKLLQPISEDVEVTLLCRKKRVTRSEFY
                     QANQVGLKPSLVVEIRNFEYENQELAKFEGKQYHILKTYPIDSEILELTLSEVLK"
     gene            complement(7272..7553)
                     /locus_tag="VYN15_000941"
     CDS             complement(7272..7553)
                     /locus_tag="VYN15_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452285.1"
                     /translation="MDNVQLLELLKLKLGIATKLRDKPLEKIIEAVKTELEDNLGVLL
                     DLDSSEDQMFVVDFAAFRYEGGVDMPRHLQWRLHNLQIASKKEVKNVES"
     gene            complement(7556..7825)
                     /locus_tag="VYN15_000942"
     CDS             complement(7556..7825)
                     /locus_tag="VYN15_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452286.1"
                     /translation="MVYKVIRPFKDLRDPKKHCYKVGDNYPRVKHKLDKEFAETLLNG
                     ANSAGSIFLMNVEDKDMSKDDTLTTEVEKEETKVVDGKPEEGDEE"
     gene            complement(7837..9003)
                     /locus_tag="VYN15_000943"
     CDS             complement(7837..9003)
                     /locus_tag="VYN15_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEV1452287.1"
                     /translation="MNKALIFGARMRAKATKVVELEETIEELNKRSVVELEKLDRAKN
                     DEEVLAVEKTVDGLQREIEEKEAEKVQLENEIDELDKQIKEQNRKAPTPGKMEERGGK
                     TLGQREAFNHYLRTKEARADGFKSAEGEAIIPVELMTPKEAKQDKTDLTSLVNIVNVK
                     NASGKWSVVKLTDQAMNTVEELEENPELAKPTFTKVNYEIKTRRGHLPVSQEFIDDAD
                     YDVMGLVAKQTKNQERITKNKEIAKVLKTATSKSAAGLDGLKDILNVELKTYYNATIV
                     CTQSMFAALDKIKDKDGRYMLQTDITSPTGYKFAGRVIVVYPDDIIGESKGDLKAFIG
                     DVGEFATLFDRAQTTVKWQDDKIYGQYLATANRFDVVKVDGDAGFYVTYTDAVL"
     gene            complement(9000..9575)
                     /locus_tag="VYN15_000944"
     CDS             complement(9000..9575)
                     /locus_tag="VYN15_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HEV1452288.1"
                     /translation="MQKRNSYRATQFQTREEESGDLVLSGYFIKFDEETELWRGYHEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFKL"
     gene            complement(9559..10761)
                     /locus_tag="VYN15_000945"
     CDS             complement(9559..10761)
                     /locus_tag="VYN15_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV1452289.1"
                     /translation="MGIFEKFWKRNKPSKSINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCKHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDEVVHFV
                     INPDPDILYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            complement(10779..10997)
                     /locus_tag="VYN15_000946"
     CDS             complement(10779..10997)
                     /locus_tag="VYN15_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452290.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            complement(11005..12735)
                     /locus_tag="VYN15_000947"
     CDS             complement(11005..12735)
                     /locus_tag="VYN15_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEV1452291.1"
                     /translation="MGNLDKAKKYAQHVLTHREEHCEENILAAERFFRDLENPTFEMD
                     EDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVNYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYH
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     KMREKGFKIAAVGMDRKFGREFLTKMKQARFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQALANLG
                     KGGDVMRFFD"
     gene            complement(12728..13120)
                     /locus_tag="VYN15_000948"
     CDS             complement(12728..13120)
                     /locus_tag="VYN15_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HEV1452292.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYVDMGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEVLKFKNEIKKKRVTGNG"
     gene            complement(13257..13577)
                     /locus_tag="VYN15_000949"
     CDS             complement(13257..13577)
                     /locus_tag="VYN15_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV1452293.1"
                     /translation="MYNKPIRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            complement(13954..14496)
                     /locus_tag="VYN15_000950"
     CDS             complement(13954..14496)
                     /locus_tag="VYN15_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1452294.1"
                     /translation="MEFVSPIKDNDDIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEGKPFHHFLFKSRQGQNK
                     AITRERAYQIIHEAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            complement(14684..15085)
                     /locus_tag="VYN15_000951"
     CDS             complement(14684..15085)
                     /locus_tag="VYN15_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1452295.1"
                     /translation="MKKLSDEDLKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     SVGISKPTETIAVRIADDPTLKFLEGFKAIINKLLINLVDEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAILKGEL"
     gene            complement(15222..15632)
                     /locus_tag="VYN15_000952"
     CDS             complement(15222..15632)
                     /locus_tag="VYN15_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452296.1"
                     /translation="MIPKFRGLSIDEKSKGEWQYGHLIEDRGRAFIINEVVEANEQYI
                     TIGSWCPVNPATLGQSTGLRDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTYIGGMP
                     AVYLKGFGDGYAWTEYEEIIGNVYENPELLEVNE"
     gene            complement(15644..15922)
                     /locus_tag="VYN15_000953"
     CDS             complement(15644..15922)
                     /locus_tag="VYN15_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452297.1"
                     /translation="MKRLGIIIGAVFVIVVSPFVVQYGWNEIITTIVPVGKITVWQAL
                     GMDALLSFIWPVLSSKKESEEDYSYAVKSSISKIITCAFLIWLASLFI"
     gene            complement(16024..17106)
                     /locus_tag="VYN15_000954"
     CDS             complement(16024..17106)
                     /locus_tag="VYN15_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV1452298.1"
                     /translation="MKFLDLFAGIGGFRLGMESAGHKCIGFCEIDKFARESYKAIHNT
                     KGEIELHDITAVSDESIRGIGSVDIICGGFPCQAFSIAGNRRGFEDTRGTLFFEIARF
                     ASILRPKYLFLENVKGLLNHENGVTFETIISTLDELGYNVEWQVLNSKNFGVPQNRER
                     VFIIGHLRREHTRRIFPLSGKNQSTSNQSVMKIGNINPSGNGMNGEVYQADGLAPTLT
                     TNKGEGQKIAIKSNTIKQFGVLQPNFNQCGVVYETDGIAPTIRAYQGGGLEPKIIQRG
                     HGYNKGGEHNIAPTLTSNSYHENNHLSDGFRIRKLTPRECWRLQGFPDWAFDKAQEVN
                     SNSQLYKQAGNSVTVNVIAAIAKELS"
     gene            complement(17137..17424)
                     /locus_tag="VYN15_000955"
     CDS             complement(17137..17424)
                     /locus_tag="VYN15_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452299.1"
                     /translation="MTQTLEEGMKNQSKCIKVPREIRPFDIGYRIVNKYGQALALRNG
                     ASIFDLPFLAEKAIEKEFGKNDPDFDIGKHSVEEVAIVNLSKFHSYFEERV"
     gene            complement(17424..17954)
                     /locus_tag="VYN15_000956"
     CDS             complement(17424..17954)
                     /locus_tag="VYN15_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV1452300.1"
                     /translation="MNIKALIKKYEELWNEHSPFYEPVPYTSMVELFLKELKQLDEPQ
                     KVKIPQFVADWIEVCKEHLTTSLYTAMTPNFMKENNQSFDLILWIKKASNQDLFARAW
                     LDGYEVEKEKRYLVKIKGNIKENMLVYGELLERYFFTKSFSLDDAIYSHTRKELENAK
                     IGWVFDCEGFEIEEVE"
     gene            complement(17956..18273)
                     /locus_tag="VYN15_000957"
     CDS             complement(17956..18273)
                     /locus_tag="VYN15_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452301.1"
                     /translation="MMEELKRKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMAQVVIAVYLIY
                     GGN"
     gene            complement(18441..18608)
                     /locus_tag="VYN15_000958"
     CDS             complement(18441..18608)
                     /locus_tag="VYN15_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452302.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            complement(18693..18911)
                     /locus_tag="VYN15_000959"
     CDS             complement(18693..18911)
                     /locus_tag="VYN15_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452303.1"
                     /translation="MLELYFVYNGHCKFYLGRFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGK"
     gene            complement(18921..19595)
                     /locus_tag="VYN15_000960"
     CDS             complement(18921..19595)
                     /locus_tag="VYN15_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV1452304.1"
                     /translation="MMKFLNGDCMDIMKQYPDNYFDLAIVDPPYFSGPEKRKFYGRKI
                     SPIGVSRLYGEISEWKIPNRDYFDELFRVSKNQIIWGVNYFDYSFGSGRIVWDKVNGQ
                     SSFSDCEIAYCSYHDSTRLFRYMWNGMMQGKSISEGHIQQGNKALNEVRIHPTQKPVN
                     LYLWLLQTYAKEGDKILDTHVGSASSLIACGELGFDYVGCEIDKSIFNLAQQRLDAYE
                     KQLKLF"
     gene            complement(19595..19789)
                     /locus_tag="VYN15_000961"
     CDS             complement(19595..19789)
                     /locus_tag="VYN15_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452305.1"
                     /translation="MFILKHGTREDKPFLRSAIISVTGLDISCSEEKKAMRFISRAAA
                     VQVGKALRGSFGNFYPVEVE"
     gene            complement(19804..20574)
                     /locus_tag="VYN15_000962"
     CDS             complement(19804..20574)
                     /locus_tag="VYN15_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1452306.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEVLKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            complement(20568..20726)
                     /locus_tag="VYN15_000963"
     CDS             complement(20568..20726)
                     /locus_tag="VYN15_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452307.1"
                     /translation="MGVLELIEQFEIDYYPLSYEKKTLLADQPIHQVVACLSEMASWH
                     ECGGRLVW"
     gene            complement(20714..21520)
                     /locus_tag="VYN15_000964"
     CDS             complement(20714..21520)
                     /locus_tag="VYN15_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV1452308.1"
                     /translation="MSEIKWIKITTDIFDDEKICLIDALPDPDAILVIWFKILTLAGK
                     HNSNGLLMMTDKVHYTDEMLATIFRRPLNTVRMAIGVFEQFGMIEIIDGIISLPNWEK
                     HQNVDGMEKIKEQTRNRVAKYRKKQKNLALGNVTGNVTVTDGNALEEDKDKNKNRLDK
                     DKNKKRITTTSSGSEENILELFQSEFRRLLSGFEIEEINHLLNENDVDLVKEALKTAI
                     NSGKPNIKYIGGILRNWQMNNVTTVEQVRQSEKKNKDKKEEQEAKDEWGY"
     gene            complement(21513..21809)
                     /locus_tag="VYN15_000965"
     CDS             complement(21513..21809)
                     /locus_tag="VYN15_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452309.1"
                     /translation="MEELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLLVKE
                     YLTDYEKLAKDYRYVTLKNKLLKIEKMELEGRHIYEDMRMKYRANRRKWGARYV"
     gene            complement(21825..22145)
                     /locus_tag="VYN15_000966"
     CDS             complement(21825..22145)
                     /locus_tag="VYN15_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452310.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIQGYNHAYERGREAERQEIRKNIRRPFKGFTYDNEPPQGLRPEPLALPEPKQSA
                     IRLL"
     gene            complement(22231..22488)
                     /locus_tag="VYN15_000967"
     CDS             complement(22231..22488)
                     /locus_tag="VYN15_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1452311.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCE
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            complement(22502..23212)
                     /locus_tag="VYN15_000968"
     CDS             complement(22502..23212)
                     /locus_tag="VYN15_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HEV1452312.1"
                     /translation="MNEIFNFHGQEVRTLTIDDEPWFVGKDVADILGYSKARNAITLH
                     VDEEDALKQGIPTSGGTQDMLIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRKQ
                     GGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAQSLLKKRKAR
                     VVACLGGIDSPAYADKVFAQSVFRQAEIDFKDHFNISRYDLLPKKHADAALAYWMTWE
                     PSTNTKMKIMKLNSFDDV"
     gene            23266..23691
                     /locus_tag="VYN15_000969"
     CDS             23266..23691
                     /locus_tag="VYN15_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452313.1"
                     /translation="MDYQILIQPAISVILAIISGLWSYIASKANNKAEIEKQAKEHSH
                     IVEKLEKEFHYQIDTLKQQHTLELEKVKQAHELRLQELEKVSQIDTETDKAMKMNDLI
                     YKTFTGEVDLDKALKLADKANNHKQKLNKKFIQKTSKKS"
     gene            complement(23686..23847)
                     /locus_tag="VYN15_000970"
     CDS             complement(23686..23847)
                     /locus_tag="VYN15_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452314.1"
                     /translation="MNELVWFYFVVIINLIIGFATYYASKRDRKKRINEYKKIQDDEL
                     ERIRNKFNL"
     gene            complement(23858..24055)
                     /locus_tag="VYN15_000971"
     CDS             complement(23858..24055)
                     /locus_tag="VYN15_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452315.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            complement(24072..24275)
                     /locus_tag="VYN15_000972"
     CDS             complement(24072..24275)
                     /locus_tag="VYN15_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1452316.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQAELAKQVSVTSSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            24330..24812
                     /locus_tag="VYN15_000973"
     CDS             24330..24812
                     /locus_tag="VYN15_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452317.1"
                     /translation="MKSSFFHYLKEIILYGVLVPILTVIVGFHLFTTFYPISDSLLTD
                     FLKAFTEQRILAIVFVLILCFIFFGSIYYCISCGRNRKLIPDKVYTQITTYISSVGLG
                     TAVIAVATLTLTELQFSILTGWIAFIALLLPLLKFKVQYSTYQSSDNVAQKTTENKAN
                     "
     gene            25118..25486
                     /locus_tag="VYN15_000974"
     CDS             25118..25486
                     /locus_tag="VYN15_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1452318.1"
                     /translation="MFVAFDKIKELADKQGISINILEEKLGYGTNTLYRLKRSNPSSK
                     VLKEIADYFNVSADYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            25486..25719
                     /locus_tag="VYN15_000975"
     CDS             25486..25719
                     /locus_tag="VYN15_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452319.1"
                     /translation="MTITINFTEKNSYITDYLTKHGIDTTTMDFDDFMVLMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLSREDIA"
     gene            25719..25982
                     /locus_tag="VYN15_000976"
     CDS             25719..25982
                     /locus_tag="VYN15_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1452320.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            25995..26375
                     /locus_tag="VYN15_000977"
     CDS             25995..26375
                     /locus_tag="VYN15_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV1452321.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHSSGFYNPDTNVLAIDHNLAPE
                     QQIQVALHELGHKDHTRSEYQNARLRCENEADRNMIHHLVKDALESLDDPTEFDYLKF
                     MSYYNLKTMTNEVMVKEEYLALVN"
     gene            26413..27225
                     /locus_tag="VYN15_000978"
     CDS             26413..27225
                     /locus_tag="VYN15_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV1452322.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYAKYYSN
                     LSTKELREELEEYGLKVFKYQDLDFFNIELVPEVDNRYDPNAIKVLIFDNHVGYVPAT
                     IAKTIRKYFDNKKYNFVIEGEIKGGPYKEWDEYEEKVVTNNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNISNKEVTETEAIETKTTETEHIEQNIVSDSVADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            27399..28547
                     /locus_tag="VYN15_000979"
     CDS             27399..28547
                     /locus_tag="VYN15_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1452323.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(28789..30075)
                     /locus_tag="VYN15_000980"
     CDS             complement(28789..30075)
                     /locus_tag="VYN15_000980"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV1452324.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(30306..30542)
                     /locus_tag="VYN15_000981"
     CDS             complement(30306..30542)
                     /locus_tag="VYN15_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV1452325.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            30808..31605
                     /locus_tag="VYN15_000982"
                     /pseudo
     CDS             30808..31605
                     /locus_tag="VYN15_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(31640..32486)
                     /locus_tag="VYN15_000983"
                     /pseudo
     CDS             complement(31640..32486)
                     /locus_tag="VYN15_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(32594..32667)
                     /locus_tag="VYN15_000984"
     tRNA            complement(32594..32667)
                     /locus_tag="VYN15_000984"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32631..32633),aa:Asn,seq:gtt)
BASE COUNT         9522 a         7332 c         5419 g        10394 t
ORIGIN      
        1 agggtacttg cgccagacag ttcttttttg gtctgaacaa gtgcttcaac ttgcttggca
       61 atctcagctt caacctgtgc ttgcttcggt cgaatatcat tcacgatagt ccgtttcaga
      121 gcgtccaagt cacctgacag agccgtttgt gcgctcgtag tctgcgactt aaactcttca
      181 agtctagcga cagaatccag cccaatccgc ttcgcttcct gagcgagtaa gctgcttgcg
      241 ccagcgtttc tcaaggcttc ttcagccctg cgcttagctt ctttcaatgg cccgttgtca
      301 aagctattaa agcgctgatt gatagtgtca gacagttctt gcttgacttc ttccgccttg
      361 gccttggcaa gttcgatgcc gtcagaaatt tcctgtctaa gcaatccagc cttatgatca
      421 aagtctaagt cagcattttg aagagccttt tcaagggcaa cttcttgtgc agattctgtt
      481 actccaagaa tggcatccgc tgcgctagat aagccaccag atgttctaga accaccagct
      541 cctgccttat catcgagaat cagagagata tattcttctt ttaaggcatc gaactcataa
      601 gcaatagctt tcttaaatac atcaacatta tgtttccagc tcttgagatt gaccgtatca
      661 cccatgtgaa caacttgccc atcaagttca taagcttcaa tcttgatagc gtcagagatc
      721 ttgtcaatgc cctcgtttga gaacttagcc tgtgcccact tctgcaactc ttcaacggat
      781 tttgcgttgt tgttctcata ctctttttcg tttatgtaag gataagaatt aataagagga
      841 ctatcaacag tcactctgat agttgtttcc ttttcagcac cttcaggttt aaaagtcgac
      901 tttgcgtgaa ttcttgtgac aacattctga ctgttttttg tgcgttggta gttcttcaga
      961 tttttgtgcg ttgtaataac aacaccacga ttctccccac gactcttctt tacagtcatc
     1021 gcaaagttat cacgcaccag ctcgccttcc cacgttccga cgatactatg cttgccgtcc
     1081 agcaatacag agtacagggt ttctgtctca gtcgtgttga atgtcctacg gtcctggata
     1141 tcactgttga atgagaagtc tccaagagct gttttggtgt tttgtaccat gcgagaaaga
     1201 gccatgccac aactctgact agtcacactc atttgtgtga tagatcgttg catcacatca
     1261 tctgaaatgt gataggctgt gatttccaga tggtcattgt gctcaacagg tttcttaatg
     1321 cgaaatagct gcgcaccaag aacaggagtc ggcgctttta tcaacatatc ttcttggatg
     1381 agctgataaa taccagagtc ggaaatggga tatttcacag ttaaggtgaa atcaccattc
     1441 atgatctctt taacaatcgc cgaagtcgct tcatgaagtg gctccccgtt ccatcgaacg
     1501 gttcttacat ctttattaag tagataaagc aattatgccc acccccaaac cgtttcgatt
     1561 tcaatcgatt gaatacctgg gcctaaaaca accccaatat tcttaacttt cgctggatca
     1621 actgtgataa aatcccctga ccatttcact ggcttccctg ttgtcgtttt aaagctagga
     1681 ttgtcaggat tattaaccat cacaagcgat tctgagagtt tttcaagcct aatgacctga
     1741 ccagcgattg taaatgaagt ctcaacaacg ctctgaccaa cgattgtgat tttaggaaaa
     1801 gcaagagcag aaccttgcac attcagagtc ccgcttcttg tcaatctctg agtatcagtt
     1861 gctttgaagt attttgtagg atggcaagtg aaggtcgctt tggtcatgta aagaccaggt
     1921 tgtacttctt caaggtcagt cacattgacc ttatagcacc agagacgagt tgttttgact
     1981 cgctcgctct ctaaccagaa cttctcacgg ataaacagac tcataaattg gttcatctgc
     2041 tcctcagtcg gtttgactaa gtaaatcgta taagatttct tgaccagttc cctgtgcttg
     2101 ttcgtctgaa caattgcccc actgatacca ccatgctcca aaagagctgt cttgctctct
     2161 cccagagcaa ttgaaggaga atcatggaca atgactttaa acggaaaaga cgatgttctc
     2221 acaccgtcaa tcacaagctc attatgcttt atcatgtaac ccctgctctc aattgtgtct
     2281 tacgttgcaa ctcgtcagca atacgctgag ccacctcatc agcaatacga ctgatgtcgg
     2341 cttcttctct gacagtgttg ccagtaatgg taatgttaat ggttggtgaa gttccaccca
     2401 tagtttgagc gatacctcga ccgatggctc caagcgtttt gtcgttaagt ggcaatactg
     2461 cttcattccc agcttcacca ccaaccatta tgttattacc attcattcca aagatagttg
     2521 gtttcgtcat gataccgcct ttggcatacc attcgattcc aatacttgga acaccttgac
     2581 tcaaccaatc taatggattg gccgaaccac tcacgtaaaa gtgaggtagt gggatatgtg
     2641 gccagctgat gttgaagtta aacaatcctt tgatggcttc aatagctgaa gaaacagcat
     2701 cccttgcacc attgatagca cttgaaatgg tactcttgat accttcccaa acacttgaga
     2761 cagtactaga tatagcattt aacacatttg agacagtgtc cttgatgctg ttccagatat
     2821 ttgatacagt tcctgaaatg ccgttgagaa tatttgaaat ataactctgg atagctgaga
     2881 aaatagtctg aacaatgctt tggatagctt gccatacagt agagaatacc cccttaatag
     2941 tttcccaagc gcctgaccaa tcaccattga tgatctgcat aactgcttga atgataccaa
     3001 ggacaacgtt tattgcagtc tcaacaacag tcttaatgat ttcccaagct gttgtaatga
     3061 caagttggat attatcccaa ccagcttgaa tgagtggacc taaaatttcc agaattgtgc
     3121 ttataaccgt atagatagca ttccagacag tctcagcact tgctcgaata agttcctggt
     3181 tctccgtcca ccaagcaaca accgttccaa agatactcat gacaaaatta gaaatctctg
     3241 atacgactgc attgataact tcaagaatcg cattccaaac ggtcgtgacc gcatctcgaa
     3301 aaccttcgtt agtttcccag agatatttta caataacaat aattgcagca actgcagcag
     3361 caattgcaat agctgttcca ataattggca atgcggcaat tatcatttct ccaatagata
     3421 tttttaaaaa ctcagcaagg gcttgcaacg ataagaatat gggggctatg acccctacag
     3481 cagtcacaac tgttcctaaa ataacaacaa aatcttttac tggagcaggt aaggaactga
     3541 acagctcagc tacacctttc acaatcgttg ccaaggtttg aaaaacagga atcatcattt
     3601 ctagaagagg ttgaccaata gcagataatg cattggtccc agcttgtttc agattcccca
     3661 tcacgttttc caggccgtct gattctcttg cagcctgtcc aagagctcct gagagtttat
     3721 ttccgtcttc gaccatctga agcaaggtca attgcttctg cgcttcgctc aagtccttga
     3781 atgactttcc gtacaattta tttgcagcgg cattcctggt cgtttctgtt gcagaaatgc
     3841 caagagccgc atcgttagca aagtttccct tcaaaaaaga ttgtaagctc tctgtcacgc
     3901 tctcaataga tttgtcatag aaggctgcac cgtctgctgc tgccctagtt gcacgagaag
     3961 taagatccaa agcttctgct gtatccaatc ctgaagtttt tgcaaatgaa gccatctgag
     4021 tgaatgatcc ttgcaatcgc tctgggacaa tatccatttc ctgaccaata gcattcaacg
     4081 cttctcttgc ttgggtttcc atatctccga aaacggtagt aaattgagca ttactagctt
     4141 gcatttgagc agctgcttct aacgcttctt ttcctacttc cacaagcttt tctgaaatag
     4201 cactcaactt ctcactaaac tgttgaagta gttctgctct taaatttctt gagatttcac
     4261 ttaaactttc ttgagtgcta tcagcagcag actttgttcc tttcatctca tcattgagat
     4321 gattgaatgc tgtcttagcc tgatttagct ctgcttccat cctgttggct tgtgtggagt
     4381 tctcaccaaa ttctttttta gtgatttcca attgctgttc tagatttgaa atctgtttac
     4441 ttacaatctc agactgagca ccaatctttt tctgagcaag agcatttctc tcggcttcac
     4501 tagcatttga acccaaagcg ctttcttgca gtttgaatga acttgtcacc ttactcatct
     4561 ctgaagcaag ttgactctgc tcattttgca actcttttaa ttggttcttg ttgttctgag
     4621 tagcactccc attctcatta agcgcctgat tcacatttgc aagcttaccc tcatatcctt
     4681 ttaggacgtt ttgagtaact tctacttcac gttggaaagc acggtactgg tcagcaccga
     4741 tatcgccatt tttgaattgc tgttccacct gagactgagc ttgtctcaag gtttctagtt
     4801 tctctttggt cgtcgaaact tgcttttgca agacctcttg cttctgagtc aggagcgtta
     4861 cgttccctgt atcaaacttc aatgctttgt caatctgtct caactcctga cttgcatcag
     4921 tagcagcctt attgacattt ttcagcgcct tctgtaaggg ttgcgtgtcg ccatcgattt
     4981 caattttaat acctttgata tttcctgcca tatttcctcc tttctcaaaa aaatagaaaa
     5041 gcgctgagag aacttctacc actgataatg cagccagacc aaggaacttg gtctcagaat
     5101 cgctctctca gcactcattt ttctttaaaa accgtcaaaa tcagcttgcg tggctttccg
     5161 ttcgccaccc ttatcctcgc tccgtagatt cacataatcc gtctgataat ccagagccat
     5221 tccgattgaa atgtgcttta gatcatcaat agaaagacca gtttctttac agcaagataa
     5281 gtaggtttct actgtgaaga tttcttcgct agctgattct gattcatctg gtgctttttt
     5341 gtcgtcatgc tcgcattcag catttccatc aatacaggcc caacttcctg aatcggaaag
     5401 acttccattt ccatgaagaa ttgttcataa ggcttgatgt gaggattttc agatttagca
     5461 aaggtccaaa aaagacggtt gaaaaaggtc atgtcaaaat ctgacaacat cgaaatatca
     5521 atattagtcg ctgtcaattc cttgtcggtt tccaacttgt tcaattcatt catgaatgat
     5581 tgatttttca acatcgagaa caaatcttga aaataatctt ttccaaattg ttgcttgtaa
     5641 gcaataggag tatagccgtt ggtccccaac tcatactcct gatcaccaac caaaacgatt
     5701 ttacgcatag atcttctcct taagctgcaa ctgcagtagg ttcatacact ttcttgaacc
     5761 agttgtcata cgcatccttg tcatcagctg atgtgataga acgcttgaca actgtatcca
     5821 atggacgcgg gctagctttg aaactaagtt cacgttcgtt ggttgatgtc ccgttcttag
     5881 tttttgagcc aagagatggg cgactggcaa aacagtagta catcacatag cgagtcttgt
     5941 ttttgtcgcc ttcaaactgg aacatcattg cgaactctgt caagctcgca tctgcttttt
     6001 cagtcataac accagtttga gggtccttga tttcaccaag aatttttgtc gcaaattcat
     6061 caatgatgtg tgggatttta agtttaccct catatccttc gtttgaattc atgaaatggt
     6121 aatccttgtt gtctgctttg atagtggttg tttccccttt agtatcaagt gtcagatcta
     6181 ttgctccagg aaaacgaaaa acatcgccgt aagtgataac tccatctgct gcaagtgtct
     6241 tgataggtgc gatatgtaca ttttctaggc caaaggttac tttattttct tgagtcatgt
     6301 cattcctcct tagtatagat agactgtgta agacttgaca tagagtcttt cagtctcgat
     6361 aaatgtttct tcttgaactt caaaaaagag cttgtggttt gcccacagct cttccagacg
     6421 ttcttccaaa tcttcatcct tactctcaaa agccagctca actgtcacgc tcttaatctg
     6481 atgattaacc gtgttgtcag ctgcattgat ggctggaatt gattcataat agaccagata
     6541 aggtaggtta ggagcgtttc caattttaaa cgctcgataa gtgacaggca agtttgcctg
     6601 ttccaaaata gcagcaaagt ctgatagctt catttcccaa tctccttgat tcgcttctca
     6661 aagttttctt taactttctc ctcaacaggt ttaatatgtg gaaatgcccg actacgaccg
     6721 ccatttctca aaacatgccc attttctagt aagtgagtta aacgataggt tggagctgcg
     6781 ttgtagatga cgtatgaccc cttagcattt ttcttgaagc gccaatttct agcatacttt
     6841 ccatgacgtt ttggactagt cgcttttaat tccgtaacgg cttcgtttac aacgtcctca
     6901 gcaatcaggt caatcttatc ttctacctca gcagagtact ctgccattgc ctttgcaatt
     6961 tcattcgcta aatcacttgt taagctcatt tcaacacctc tgacaaagtc aactctaaaa
     7021 tttcagaatc aataggatag gttttcaaga tatgatattg cttgccttcg aacttcgcaa
     7081 gctcttgatt ctcatactca aaatttcgaa tctcaacgac caagctcggt ttaagcccta
     7141 cctgattcgc ctgataaaat tcagagcgag tgaccctctt tttgcgacat aggagagtaa
     7201 cttcaacatc ttcagagatt ggttgtagta gtttatcctt acctgtgact tccttagaga
     7261 tcagtgtgat ttcatgattc cacattcttg acctctttct ttgatgctat ctgtaaatta
     7321 tgcagtcgcc actgaaggtg acgtggcata tccaccccac cctcatagcg aaaggctgca
     7381 aaatcaacta caaacatttg gtcttctgag ctgtctaagt caagtagaac tcctaagtta
     7441 tcttctagtt ctgttttgac agcttcgatg attttctcca agggcttatc gcgtagtttt
     7501 gttgctatac ccaattttag cttaagcaat tctaataatt gaacattgtc cataactact
     7561 cctcgtctcc ctcttcaggt ttcccatcta ctacctttgt ttcttccttt tctacttctg
     7621 tagttaatgt gtcatctttc gacatatcct tatcttctac attcatcaaa aagatagatc
     7681 ctgcactatt tgccccattt agcagagtct ccgcaaactc tttatcaagt ttgtgcttaa
     7741 ctctagggta attatcccca accttatagc aatgtttctt tgggtctcgt aagtccttaa
     7801 aaggacggat taccttatat accatttact acctccttac aaaacagcat ctgtataggt
     7861 cacataaaat cctgcatctc cgtctacttt tactacatca aaacgattag cggttgccaa
     7921 atactgaccg tagattttgt catcttgcca tttgacagta gtctgcgcac ggtcaaacaa
     7981 tgtcgcaaat tctccaacgt caccgatgaa ggctttcaaa tctcccttgc tttctccaat
     8041 gatatcatct ggataaacaa caataacacg accagcaaac ttgtagccag ttggagatgt
     8101 gatatctgtt tggagcatgt agcgaccgtc cttgtccttg attttatcaa gagcagcgaa
     8161 catagattga gtacatacga tagttgcatt gtagtatgtt ttcaattcca cgttgagaat
     8221 atctttcaag ccgtccaaac cagctgcgct tttagatgta gctgtcttga gaactttagc
     8281 gatctcttta ttcttagtga tacgttcttg gttcttagtt tgtttagcaa ccaatcccat
     8341 gacatcgtag tcagcgtcat caataaattc ttgagatact ggcaaatgac cacgacgtgt
     8401 tttgatttca tagttcacct ttgtaaaggt tggtttagcc aattcagggt tttcttccaa
     8461 ctcttcaaca gtgttcattg cttgatcagt caattttaca actgaccatt taccgcttgc
     8521 gttcttgaca ttaacgatgt tgaccaatga agtcagatct gtcttgtctt gtttcgcttc
     8581 tttaggcgtc atcaattcaa caggaatgat tgcttcccct tcggcagatt tgaaaccatc
     8641 agcacgcgct tcttttgttc gtaagtaatg attaaatgct tcacgttgtc ccaatgtctt
     8701 tcctcctcgt tcttccattt tccccggagt tggtgcttta cgattttgct ctttgatttg
     8761 tttatctaac tcatcgatct cgttttcaag ctgtactttt tcagcttctt tttcttcaat
     8821 ttccctttga agaccgtcta cagtcttttc aactgctaaa acttcttcat catttttagc
     8881 acgatccaac ttttctaact caacaaccga acgtttgttc aattcttcga tagtttcttc
     8941 caactcaact accttagttg cttttgctcg catacgagca ccaaagatta atgccttatt
     9001 catagcttaa atttctcctt aatttctttc ttgcgcttgt ctagcgcttc acgattagca
     9061 cgcttctgac tttcgaagtc tttttgtcgt gcagcaattt ccgtttgtgg ataggctggg
     9121 aaagtacatg gactcacttc aaagatttct agctctaaga cagtgtccaa atacgaacca
     9181 tcttcacgtt cttccgtttc gatttttacc gggataaagc caaagctaca ccctataaca
     9241 tctccacgct tgacacgggc ataggcccca acagcttgag gatcatcctt gttaatgatg
     9301 atatctccaa aaagaccaac atcatcaaca cccagtgtca gagttccgtt acctgttcga
     9361 ccgagaacaa ggctatcatc atggttaaat aaagctctga tatcagcgtc tgtgacagct
     9421 ttctcaacac cagcacgctt gattacttca tgataaccac gccacaactc cgtctcttca
     9481 tcaaatttta taaaatagcc actcaacacc aagtctccag attcttcttc tctcgtttga
     9541 aattgagtgg cacgatagct atttcgcttt tgcattctct tcctcacctc ccttcagttt
     9601 attttgatct cctagtttct cctgagggag aaagttttca agaacaatca actcttccat
     9661 ctcaggatca ggagccatcc ctagccaatc cctccactca ttacgacgca ttgcagcact
     9721 gtttgccatt tgttgagcaa cagcagacaa ctccgtaatg ttgtaagaga agagtgaacg
     9781 aggatttagc ttgaagtaac gattgctaga caaaagtaag tccctggtta gtgtttgagt
     9841 aatagtggta gcaatactca tgacagtcgt atttacaaag ttgttatact ctgtcttgtt
     9901 gaactctcct acacccaaaa taaaagcagg tactcctaat agacctgcaa ctgttctttt
     9961 atccaattcc acagactcgt ttaaagcgat gtccgttaga ctaagcggtt ttacctgctg
    10021 aatgtccagc aatgcctctg gaacaatcca tggagcgcca accctgctag tactcaaata
    10081 cttctcagcg atacgctcac gcccttgctc cgaatctagt tcagcactag acgagtctac
    10141 tttaacgata agactaggaa tattcttccc gttcataaag ctttttttag tcttggtagc
    10201 catgttcaaa ctttgaacca catctgtcaa cgtcacccta aaaccagtac caatgtatag
    10261 aatatctgga tctggattga tgacgaagtg gactacttca tcaggggaat attcttcacc
    10321 cctaaatgag attacatagg aatccttatc tgtttggaat gaaacctctc tcatcggaaa
    10381 tggtcttaga ttagaaatat aatccgtaac aggttcatat tccacatgta ggacagagtt
    10441 cccatcgcca tataaaagca aatcgcgcac aatcttgaaa atccatgact tccttgtcat
    10501 gtgtttacac ggattgatat caatctttct agcaagccca tcacggattc tgatatcacc
    10561 tttatctgta ttctccatca agtggatggt catattagag accaaatcag caatcttatt
    10621 aaccgctgtc accacatctg gatttctggc caaaggtaca tacgagtcca tcaggtttga
    10681 caaccctaaa tctgaatgac tcagcatgtt gattgactta cttggcttgt ttcgtttcca
    10741 aaacttttca aaaataccca tgtttcctca cctcctttct aacgaaaagt attttgaaaa
    10801 agtgaatcaa agtgtttatt tcttacgata ttctgactga catcaattac ctgtttttcc
    10861 cattttactg tttcagccat caaatttttc atatgtcttt gacgaatagt tactacttcc
    10921 ccgtttaaaa ttactttaac tcgccctttg ttgatcagca agttaatttc atgttctgat
    10981 aatactattt cattcataat tcacctaatc aaagaatctc atcacatcac cacccttgcc
    11041 aagattagca agagcctgta tacaagcaaa gacgctggca tcaaacaagt caatccttgc
    11101 agtcccaccg tctccatcta atttctcata ttgcacagca tcgtccacct tttcaattgc
    11161 tctaacattg ctcacacagt attcgtaagc atcagaatga agatagtaaa attctttatt
    11221 cttaacttta aactcaatcc gtctgaatcc ctctgatttc agataaaaaa gctgaggttg
    11281 gtcaatcatc ttgaaccgag cttgtttcat cttcgtcaag aactcacggc caaacttcct
    11341 atccattccg acagcagcaa tcttgaaccc tttctccctc atcttgatga accatttgac
    11401 gatatcatca tagaggacgg tcggagtgtt gctcatcgtc aaccaaccgt cagactgcca
    11461 cccaaagagt ggaatcccgt catcattagc ttttttctga gcattaatcc gagggaagaa
    11521 agcatgtgtg atacagatat caacgtcttt ctcaccgtca tgatagacac catagagagc
    11581 agcagctgtt aagtcgtgca atcttgacaa gtccgcacca ccataccaac gaataggcaa
    11641 acgtgccagc tcttctaaac tccaatcgta gcaactatcc gacgcaataa actcatcagg
    11701 attaaaataa gcgttcatag agttagtgaa gatattcaag gtcttattga aaaactcatt
    11761 tcttgtctga ggatcattca tagcctgctc tgcttcttcc ttgagagcct tgagcgaaac
    11821 cgtgacaccc catgacggat tagccatctt gaggatattc tcgtccagat agttcaccac
    11881 gtccccatca gcagattgat tagccttaca gatgaagatg aaaaatgaat catcagtgac
    11941 taattgcttg agcacctttt gacagtattt cagacggtta gcaaggaacc cggtaggaat
    12001 atccccagct gtagagataa caaaaagcat actgttacgg tatgctgaca ttgttttttt
    12061 cataagacca tgtttcttac tgttcctcat tgtgtgagct tcgtccaaga tgataacatt
    12121 tccgttcaaa gagtccagac ggctctcatc attcgctaaa gcctggataa agaaagaacc
    12181 ttcatcacca aaattggcgg tgatagagtg ttcttggtta ttatccttga tacgaatgtt
    12241 cttatcgttc cagcgttcaa cgttgaatct taaaaaacca aaagcttcca tcgcttgctt
    12301 gactgagtta gcaacgatat agcatttgga accgctatct gtatctaata tctgataagc
    12361 aagtgcgatt gcagcagtaa acgaggtctt cccattcttc cgagcaagca tgatgagcgc
    12421 ttctttgaac ctgcgctcat tcgtaccctt gtagtaaaaa ccaaacagat taactacaac
    12481 gaaatgttgc cacggttgca aaagcaatgg cttgttacgg atagataccg caaacatatc
    12541 atcgccctgc tgatgaacta tcacgttctc gataaagtga ataacaaaat ccaccatatc
    12601 ctcatccatc tcaaaggttg gattttctaa atcacggaaa aaacgttcag cagcaaggat
    12661 gttttcttcg caatgttctt ctcggtgagt taagacgtgt tgagcgtatt ttttagcttt
    12721 atcaagatta cccattgcca gtcactcgct tcttcttgat ttcgttcttg aacttcagta
    12781 cctcagtaag aactgactca ccctcttgtt ctactacctc accgagcgac ttaggattca
    12841 tcatcaactg attagagtag ctgagtatat ctttcctcaa aatttccatc gctgtcaaga
    12901 ttggaacttt gcgctcattt tcagcaccag ccttattgac gtaggtgtct gttactggat
    12961 aacccatatc aacataatct tgagcaagtt tctgatactg gtataacata cctgcaaaaa
    13021 tgtcaatgat catttcgaac tctttacgat aagttcccaa gtctttcatc tgcttgacca
    13081 cttttgactt aatcgacttt gctgtaattg gtttagccaa aaactacctc ctttcgtcaa
    13141 aatcgcttag tttttacccc ctttttgttt gaaggccccc gacttggaaa aagttccctt
    13201 caccggtacc ctactggcca aaatgatttt tcaaaaagag gggggattaa aaattttcat
    13261 ttttcatttt tgaaaaaatt taaaaattct ttttttcttt ttttctgcca atacaatcct
    13321 tggttgatta ctctatcgtt cactctatca tgaaacgtat tatgtttctt attcgtcaat
    13381 ggcaagcaat tccattcaac aaattcaagc tcaggatatt cagacacagg aaagatatga
    13441 tgtaccattt ctgcttgaac agaaattccg taacgcaaac tttcttggca aagataatca
    13501 tgcttacgca ttatcctatc acggaacttc tcccacttct tagatttcaa ggatggtctg
    13561 ataggtttgt tatacatctc aaacctcctt tctcaatgct aaaagggaca ggcctttgac
    13621 ctatcccctc ctcatacaag aaatctatgc taccataata aacctttttt tgtgagactt
    13681 caagatgtct tttgtctcat tctgattctt taaaaaaatt attccatttt actagtatgg
    13741 ctgttaacgg tatatgcatt ccatttacaa atacggtatt cttttaccat ttttcacctc
    13801 ttgtaactat accaatttta tccctcactt tcacatatct tatattttgt taaactcact
    13861 ctgaatctca aacccttact aagcatgggt tttgaagagt ttcatttttt tagtttatgc
    13921 ttaactcatt atgtgaaagt aatatctaaa aaattaaatg acaaagttcc gtagtgcgtc
    13981 atcaagctct gcttgctcta tccctatgta tctcagggtg attgcaggtg atgagtgatt
    14041 gaacattttc tgtaatgttc ctacgtcctt tgtcttgttg taatatttat agccgaatgt
    14101 cttgcgcatt gtatgtgtgc caacattatc aatgccaagt tcttcagctg cttcatgtat
    14161 gatttgatag gctcgctcac gagtgatcgc tttattctga ccttgcctac tcttgaataa
    14221 gaaatgatga aatggtttgc cttcaacata tctcctcatt tctttcttga gttcttttgt
    14281 catccgtctt gttatctgct tgccagtctt ccgttctctc agtttgatgt gccaaccttg
    14341 aacatcttta actttcaagg taagtatatc tccgactcgt aagccagtat tcaggcctgt
    14401 gatgaatagc atataataca tctcattcca ttctctgaga taatctttca tagcttgaat
    14461 atcatcattg tcttttatcg gtgatacaaa ttccataact gcctcctttc tacaaaacaa
    14521 aaagccagct ggttgctgac tcatgatgtt cctctgttaa acaacttttc tgtaaaaata
    14581 ggatgactcc aacatgtgat ttgtgttttt gtttcagaag ttcatgctat cataatagac
    14641 ctttttttgt gagacttcaa gatgtctttt gtctcaatct tatttacaac tcacctttca
    14701 gtatagcgta ctgttctaag ataattcttc tacgtcgata gattgtagct ttgctcatga
    14761 atttctgttc tgctatttct tcccatctca gttgaggata tctccagcgc agattaaaga
    14821 tttccttatc ttcatcaact agattgatca aaagtttgtt aataatagct ttgaaccctt
    14881 cgagaaattt taaggttgga tcatctgcga ttctgactgc gatagtttcg gtaggtttgc
    14941 ttattcctac gctgggacca ctctgagcat ctgggtttcg agtttctaat tctagtcttc
    15001 tcaaatctat tgtacgttga atgttttgaa atttgaaaag ttctctgtct aatgttttga
    15061 ggtcttcgtc gctcaatttt ttcaatttcc acctccaagt ttttcaaaaa tgtaaacaag
    15121 ttatcaaaat tgtcgagatc ggatatctat tcctacttgt cttcgttcca taaaatctaa
    15181 ctgtttgttc agtaatacca aacatagtat tttaaaatat ctcactcgtt gacctccaaa
    15241 agctccggat tttcgtagac attgccgatg atttcctcat attccgtcca cgcatatcca
    15301 tctccaaatc cttttaggta tacagcaggc attccaccta tgtatgtgcc accgtattct
    15361 ttttctaaat atacttcatg gagacatcct cttgtacatt taacgatgtc accgatgaat
    15421 acctccttgc cgttcttgtc tctgagtcct gttgattgtc ctaatgttgc tggatttaca
    15481 ggacaccaag aacctatagt aatgtattgt tcattggctt ctaccacttc gttgataata
    15541 aatgctcttc ctctatcttc aattaaatgt ccgtattgcc attctccttt gcttttttcg
    15601 tcaatggata accctctaaa ttttggtatc atgctaacac tccttaaata aacaaactag
    15661 ctaaccatat caaaaatgca catgtaatga tttttgaaat actgctcttt accgcatacg
    15721 aataatcctc ttcagattct tttttgctag atagcacagg ccagatgaaa gatagtagtg
    15781 catccatccc taatgcttgc cagactgtaa ttttaccaac tggaacaatt gttgtgataa
    15841 tctcattcca tccatactga actacaaacg gcgatacaac gattacaaat accgccccaa
    15901 taatgattcc tagtcttttc attttataaa tcctcctctt tgacgaaagc accatcaatc
    15961 caacgaccct accgttttct aaatcacggt caataaacca ttgtttgact ttctctattg
    16021 tgttcatgat aactcctttg ctattgctgc tatgacatta actgtcacgc tatttcctgc
    16081 ttgtttatat aattgactgt tagagttgac ctcctgcgcc ttatcaaaag cccaatcagg
    16141 aaaaccttgt aacctccagc attctctagg tgttagcttt ctaatcctaa atccatctga
    16201 taaatgattg ttttcgtgat agctattgct agttaaagta ggagcgatgt tatgttctcc
    16261 gcctttatta taaccatgcc cacgttgaat aattttaggc tcaagtcctc caccttgata
    16321 ggctctgata gttggtgcga tgccgtctgt ttcgtaaacc accccacatt ggttaaaatt
    16381 gggttgcaat accccaaatt gttttatagt attgcttttt atagctatct tttgcccctc
    16441 tcccttgttt gttgttagcg tgggagctag accatcagct tgatagactt ccccattcat
    16501 tccgttgcca gatgggttta tattcccaat tttcatgact gattggttac tagttgactg
    16561 attttttccg ctgagaggaa aaattcttct ggtatgttct cttctaagat gtccgataat
    16621 gaacactcgt tcccgatttt gggggactcc gaaattcttg ctgttaagca cttgccattc
    16681 cacgttgtac cccagttcat ccaaggttga gataatggtc tcgaatgtaa ctccattttc
    16741 gtgattgagc aatcctttaa cattctcaag gaatagatat ttaggtctga gaatagatgc
    16801 gaacctagca atttcaaaga acaaagttcc tcgtgtatct tcaaaacctc gtctgtttcc
    16861 tgcaattgag aaagcttggc acggaaatcc tccacagata atgtccacac ttccgattcc
    16921 tcgaatagat tcatctgata ctgctgtgat gtcatgtaat tctatttctc ctttcgtatt
    16981 gtgtatcgct ttatagcttt ctctagcaaa cttatcaatt tcacaaaagc caatacattt
    17041 atggccggca gactccattc ctaaacgaaa accgccaatt cctgcgaata aatccaagaa
    17101 tttcacaaca tcacctcatc cccaactttc actttctcat acacgttctt caaaataact
    17161 atgaaattta cttaaattga caatagcgac ctcttcaaca gaatgctttc cgatgtcaaa
    17221 gtctggatca ttcttcccaa attctttttc tatagctttt tcagccagaa aaggcaaatc
    17281 gaatatactt gccccatttc ttaaagcgag cgcttgaccg tatttgttca ctattcgata
    17341 ccctatatca aacggtctga tttcccttgg gacttttatg catttacttt gattcttcat
    17401 tccttcttca agtgtttgtg tcatcactcc acctcctcaa tctcaaaccc ttcacaatca
    17461 aacacccagc cgatttttgc attttctagt tctttacggg tgtgggaata tatagcatcg
    17521 tctaaactaa agctttttgt aaagaagtac ctttccaaaa gttctccata aaccaacata
    17581 ttttctttaa tattcccttt aatctttacc agataccgct tctctttttc gacctcatag
    17641 ccgtcaagcc atgcgcgagc gaagaggtct tggttgctcg cctttttaat ccataatata
    17701 agatcgaaac tttggttgtt ttctttcata aagtttggag tcatagcagt atatagacta
    17761 gttgttaaat gttctttaca aacctcaatc caatccgcca caaactgcgg aattttgact
    17821 ttttggggtt cgtctagttg tttcaactct ttcaaaaaaa gttcaaccat tgaagtataa
    17881 ggtacaggtt cataaaaagg gctgtgttca ttccacaatt cttcatactt cttaatcaat
    17941 gccttaatat tcatcttagt ttcctccata aatcaaataa actgcaataa ctacctgagc
    18001 catgcttggc gaatagccaa cccaatcatc aaactcctta gattttggca accaaccctt
    18061 agtagctccc aaatcatagt ctgtaggctt ttcatcagcg aagatacatt ccatcgctcc
    18121 cataaacgtc ataccatctt ctgccatttc ccaaaaatag tccgcccggt ctttcaccgc
    18181 ttgtggtaaa tcttgcttgg gaggttgcgg cttcccgtct tctaccgtcc agttgtatac
    18241 ttcattaact tttcgcttta actcttccat catcttccaa ctcctccact ttccgtctca
    18301 attctttatt ctttttcctc aacaaatcgc gctctagcgc tctaatacgt ctcttgcgtg
    18361 catcgcacgg tttcgaatac tcgattatct tctcttcgtt ttgatcgatc gtgcgtttca
    18421 gtccgtcaat ctcagcctgt ttatcgtact tcatcttcta aaaacctttc aatagcttct
    18481 ctgtaggaga cttccaccag accgtctaag tcgttcaggg cttcaatata gtctggacga
    18541 ccttgcccgt actgctcttt caaaaattca acaaagagat gaatttcctg ataggttact
    18601 ccaaccatgt ttcttacctc ccactaaatc agaaattccc atacatttgt gaaaattctc
    18661 aaatgctaaa tccattaaaa tatttttagc cattatttcc ctcctgaaaa agtcgctaaa
    18721 tagtaacaat ccttagaacc gtagtcaaat cgtgtcgtcc gctgaccaat gtgcttctga
    18781 aatcttggat gagtgatagc cgagaaagcc cactgatgat cttccatctg ctcaatgaga
    18841 tcatcgacat tgtcaaacct cccaaggtaa aacttgcagt gcccgttata gacgaagtaa
    18901 agctctaaca tcaatacctc ctaaaataac ttcaactgct tctcataagc atcaagtctc
    18961 tgttgagcga ggttgaaaat acttttatca atctcgcatc caacatagtc aaatcctagc
    19021 tctccgcaag caatcaagct acttgctgaa ccgacgtgag tatcaagtat tttatcgcct
    19081 tcttttgcgt aagtttgcaa taaccaaagg taaaggttga ctggtttttg tgtcggatgg
    19141 attctaacct cattcaatgc cttatttcct tgttgtatat gaccttcaga gattgattta
    19201 ccttgcatca taccattcca catgtaacga aatagcctag tactatcatg ataactgcag
    19261 tacgctatct cacaatctga aaaacttgat tgaccattaa ctttgtccca cacaatacgg
    19321 ccagaaccaa aagaatagtc gaagtagttc acaccccaaa taatttgatt tttagatacc
    19381 ctgaaaagtt catcaaaata atctctgttt ggaattttcc actctgagat ttcgccatag
    19441 agtctgctta cacctattgg actgattttc cgtccgtaaa atttcctttt ttctggacca
    19501 gaaaaatatg gtggatcaac aatagctagg tcaaagtaat tatcaggata ttgtttcatg
    19561 atgtccatgc agtcaccatt taagaatttc atcatcactc cacctcaaca gggtaaaagt
    19621 tcccaaagga acccctcaaa gcctttccaa cctgtacggc agccgcccga gaaataaacc
    19681 gcatggcttt cttctcctcg gaacacgaaa tatccaagcc agtcacactg ataattgcag
    19741 accttagaaa cggcttatcc tctcttgtcc catgctttaa aataaacatc agccacccct
    19801 attctaaaaa tattgctttc gcttgtttgt caaatcattg aaaaccatca aatggtcttt
    19861 atctacaccc ttcattagtc tggacatgaa aggtctgcca tatctttttt gaatatcggc
    19921 agaaatcaaa tttgtggtaa tgattgtgtt tgaacgctta ttcaagatat tgtagagaat
    19981 agtaaatgac cattcgctat ctttttccat tcctaaatca tccaaaacca agaacttagc
    20041 actagcaatt ttattgacca gaaactcttc ctgactaaaa tcagctttaa tcttcatcag
    20101 caagtcagtt acgttaataa aaatagcaat ctctttcgtg tactcagata gagccttaac
    20161 catagcaaaa gccaaatggc tcttacctgt tccagcttct ccttgtaaca cgatgttgtt
    20221 cctagcaccc tcagaccact cacgacaaat cctctttgca aaagctagct tttccgcttc
    20281 tttttcggtt ggtgtttcaa aattgtccaa agtagcattt ttcaaaactt catcataaag
    20341 agagaacttt tcaagatagt atttcctctc tcgctcattc tcagcattag ccagttcatt
    20401 cactctttcc tgattttctt catgaatccg ctcagattca cacatgcgac atacaacact
    20461 ctcggtcctc aatatcttta tcaaagggat gttatgcttt tcgcagaact cttcttgttg
    20521 ttctgtattc ctacgataag ataaggcgat ttcctcaaac acattgtcta ccatactagc
    20581 cgacctccgc attcatgcca gctagccatt tcagacaagc aggcaaccac ttgatgaatt
    20641 ggttggtctg ctaaaagagt tttcttctcg tagcttaacg gataatagtc aatctcgaat
    20701 tgttcaatta gttctagtac ccccattcgt ccttggcctc ctgttcttct ttcttatcct
    20761 tgttcttctt ttccgattga cgaacctgtt caacagtggt aacattgttc atctgccaat
    20821 ttcttaaaat cccaccaata tatttgatgt tcggctttcc tgagttaata gcagtcttca
    20881 atgcttcttt caccaaatcc acatcattct catttagtag atggttgatt tcttcaattt
    20941 caaatccaga taagagtcta cgaaactcag attgaaaaag ttctaagata ttttcttcac
    21001 taccactact agtagtagtt attcttttct tattcttatc tttatctaat ctattcttat
    21061 tcttatcttt atcttcttct agtgcgttac cgtccgttac tgtaacgtta cctgtaacgt
    21121 taccaagagc aagatttttt tgttttttac ggtatttggc tacacggtta cgtgtctgtt
    21181 ccttgatttt ctccattccg tcaacgtttt gatgtttttc ccaatttggc aagctaataa
    21241 taccatcgat aatctcaatc atcccaaact gttcaaaaac tccaatagcc attcttactg
    21301 tattcaatgg tctacgaaaa atagtagcta acatttcatc tgtatagtga accttatcag
    21361 tcatcatcaa caaaccatta ctgttatgtt ttccagcaag tgtcaaaatc ttgaaccata
    21421 tcactaagat ggcatcagga tcaggcaagg catcaatcag gcaaatcttt tcatcgtcaa
    21481 aaatatcggt tgtgattttt atccacttaa tttcagacat accgagcacc ccacttcctg
    21541 cgattggcac gatacttcat acgcatatcc tcatagatgt gcctgccttc cagctccatt
    21601 ttttcaatct ttagcagctt atttttaagg gtcacataac gatagtcctt tgctagtttt
    21661 tcatagtcgg ttaggtattc tttgactagt aatagatttt tataatcgtt ttcccatatc
    21721 gtaataaaat gtcttgaagt tgattccctt ccttccagtt ctttaacaat cataatcagg
    21781 ttatccagcg attcaatcaa ttcttccatt tcctgccctc ctcattacag aagtctgatt
    21841 gcagactgtt taggttctgg caaagctaat ggctcaggac gcaatccttg aggcggttcg
    21901 ttgtcgtagg taaagccctt gaacggacga cgaatattct tgcggatttc ttgacgttca
    21961 gcttctctac cacgttcgta agcatggtta tagccttgaa taatcataga cgcaaattct
    22021 tgctcttctc gtctttcttc ttccttgcgt tgttcctgca atttgatatg acggcaagcc
    22081 cctgcaaatc caagcagtaa ggctccaacc cccatcaact ggtctaaaat cggtggttca
    22141 aacattttta tctccttatc ctctttttgt gctataatat agtcaaataa ttttgctaag
    22201 accttgtcca gaagcctttt agtaaagtta ttatatttga ttagagagcc attctttgat
    22261 ggctcttttt gaccatttct taccaggtaa ttcctttgga aatcccttta agtaacgata
    22321 attatctgaa aaggtggcat acttaattcc tagaaattcg caggtagtgt tcacatccat
    22381 caactctgga tagtgatcac tatctttttc tatttcgact agccttgtga ttgtgtcctt
    22441 gataatagat ttaatccatt cagacagtga aagtagaaca ttgtccatct tcttcccctt
    22501 tctagacgtc atcaaatgag ttcaatttca tgattttcat cttggtatta gtgcttggct
    22561 cccacgtcat ccagtaagca agagcggcat ccgcatgctt cttgggtagc aagtcatagc
    22621 gactaatgtt gaagtggtct ttgaaatcaa tctcagcttg tctaaagact gattgagcaa
    22681 aaaccttatc cgcataagca ggactgtcaa taccgccaag gcaagccacg acccgagctt
    22741 tgcgcttctt cagtaacgac tgagcatagc ttggatgaat cggttgctca ctctttagat
    22801 agtcgatatc ttccagcatg gtagcctgtt gctcacgcaa tttcttttga ccagtgaata
    22861 gagcgataaa ggcatcctcg tccaagtcct cgcggataaa tccgccctgc ttgcgaatag
    22921 ctggcaagac ctctgaagtc acccagcgct tgaattcctt agcttgaggc aacttgctgg
    22981 ataagatgag agagtagaga ccagattcgt tgatgatcaa catatcctgt gttccgccac
    23041 tagtagggat gccctgtttt agggcgtcct cttcatcaac gtgaagagta atcgcatttc
    23101 tagccttgct atatcctagg atgtccgcta catccttccc gacaaaccac ggctcgtcat
    23161 caattgtcaa agtacggact tcttgtccgt gaaaattaaa aatttcgttc atagtattcc
    23221 tttctaaatt tggtataatg aaaataaaac gattggagaa atcttatgga ttatcaaatt
    23281 cttattcaac ctgcaattag tgtcattctt gcaataatct caggtttatg gtcatatatt
    23341 gcatcaaaag ctaacaataa agctgagatt gaaaaacagg ccaaagaaca ttcacatatc
    23401 gtagagaaac ttgaaaaaga atttcattat cagatagata ctctcaaaca acaacacacc
    23461 ttggaacttg aaaaagtcaa acaagctcat gaattacggt tacaagaact tgaaaaggta
    23521 tctcagattg atactgaaac cgacaaggct atgaagatga atgatcttat ctacaaaact
    23581 tttacaggcg aagttgattt ggacaaagct ttaaaattag ctgataaagc taacaatcac
    23641 aaacaaaaac taaataaaaa atttattcaa aagacttcta aaaaatcata aattaaattt
    23701 atttctaatt ctttcaagct catcatcttg tattttttta tactcgttga tgcgcttttt
    23761 tctgtctctt ttgctagcgt agtatgtagc aaaaccaatg ataagattga ttatgacaac
    23821 aaagtaaaac catactagtt cattcatctc caccctccta ctccagcacc ttactgccga
    23881 ctaccaatcg tttaacgaca acgtccatct ccttaaattc ggcattctct gcacagtagc
    23941 ggacgctctc actgatgatg tgacaaatag ataccccgta ctcgttcgcc aactccgtag
    24001 caatctccca ggcatctttg tcaatccgtg ttactttttg cgctgcgttg ttcatactat
    24061 ttcctcatgc tctaactatt ttcccaaggg ttttcaatac ccaaaatatc tacgactttt
    24121 tctttcacat aatcacttcc ttttccatac ttcagcagtt ctgaaataac tgatgatgtt
    24181 acagatactt gttttgccaa ttcggcttga gtcatatcca gctcaatcaa acgagttttg
    24241 attttagcct tgattatctt tagttcttta ctcatatttt tcctttctaa atttgatata
    24301 attaaaataa aaacgattgg aggagaataa tgaaatcttc attttttcac tatctaaagg
    24361 aaatcatctt atatggtgtc ctagttccga ttttgacagt tatcgtagga tttcaccttt
    24421 ttactacctt ctatcctatt tctgattcac tgttaacaga tttcttgaaa gcttttacag
    24481 aacaaagaat ccttgctatt gtattcgttc ttattctttg ctttatattt ttcggttcaa
    24541 tttattactg tatttcatgt ggacgaaata gaaaattgat acctgataaa gtttatacac
    24601 aaatcacaac ttacatttca tctgtaggtt tagggactgc agtgatagct gtcgctacct
    24661 tgactctcac agaattacag ttttcaatcc ttacaggttg gattgctttt atcgctttgt
    24721 tgttgccact tctgaagttt aaagtccaat acagcaccta tcaaagtagc gacaatgtag
    24781 cacagaaaac taccgaaaac aaagccaatt aagaaaggct ctaccattct cctctccccc
    24841 tttcttttaa aaaattatct aaaaagttag cgaacttctt gacaactcta gtcaaatgtt
    24901 ttaaaataaa aacatagaga aaagacctac taaaagtaag ttttacctac agtaaacgga
    24961 cgccaatcag ttttgtaagg ctttattttt tagttgtcta gttcgctaac tctttagctt
    25021 acgaatatta ttttaaaaca tttgactaaa taagtcaact attttctaca aatattttaa
    25081 aattattttt cgtttgctta gaaaggttga aaaattaatg tttgtagcat tcgataaaat
    25141 aaaagaatta gctgataaac aggggatttc tataaatatt ttagaagaaa aacttggtta
    25201 tggaactaat actttatatc gattaaaaag aagtaatcct agttcaaaag ttttaaaaga
    25261 aatagctgat tattttaatg taagtgctga ctacctactc ggacggacag ataatcctgc
    25321 tatcgctgga agtgatgaat ttgctcaagt aaatggacaa atcatagact tacgcaaagc
    25381 agcagccaac accatgttat ttgacggaaa accactaaat gaagatgata tcgacttcat
    25441 cacatccgtt ctatccgccc acttcaaaag caaaggagaa cgctaatgac tatcacgatc
    25501 aatttcacag aaaaaaactc ctacatcacg gactacctaa ccaaacacgg tatcgacaca
    25561 acaaccatgg attttgacga cttcatggta ctcatggaag atatcgaaga cgcacgagca
    25621 gccgaccaag cctatatgga gtatttagcc gacccagcta cttataccat ggatgaggtc
    25681 ttggatgaac taggactatc tcgagaggat attgcttaat gtatcggcta gatattgata
    25741 aaaaagctct caagcaactt aaaaaactag ataccccaac cagaaaacaa atcctatcct
    25801 ggcttgctaa aaacattgaa aacacgacca atccacgaca acacggaaaa gcactaaaag
    25861 ccaaccttgc aggttactgg cgatacagag tagagaatta ccgcatcatc tgtgatatcc
    25921 aagacgataa actagtcgtc ctagccgtgg aaatcgccca ccgcagagat gtttataaat
    25981 aacgaaggag aactatgaca ctcgctaaac tctgcgaaga atatcaagta gagctttgtc
    26041 tcttcgacgg ttcaaactgg cacagtagcg gtttctacaa tccagacaca aacgtactcg
    26101 ctattgacca caacttagct cctgaacaac aaatccaagt cgccctacac gaactcggac
    26161 acaaagacca tacacgctca gagtaccaaa acgctcgcct acgctgtgaa aacgaagctg
    26221 ataggaatat gatccatcat ctcgtgaaag acgcactaga aagcttagac gaccccacag
    26281 agtttgatta cctcaaattc atgtcttact acaatctaaa aactatgact aatgaagtca
    26341 tggtcaagga agagtacttg gcattagtaa attaaaaatt gcattgaaga tatttatata
    26401 gaggggaaat atatgcaaaa gactgttgaa aaaatattat tcagagtcgc tggagtgaca
    26461 aaatataaaa aagcagtaaa agaagcttgc aatatgattg ctgaagataa cggaatccca
    26521 gaatatgcaa agtactatag caatttatca actaaggaac ttagagaaga acttgaagaa
    26581 tatggtctga aagttttcaa atatcaagat ttagactttt tcaatattga gctcgttcca
    26641 gaagtagata atagatatga tcctaatgct ataaaagttt tgatatttga taatcatgta
    26701 ggatatgttc ctgcaaccat tgctaaaaca atacgaaaat attttgataa taaaaaatat
    26761 aactttgtaa tagagggaga gataaaaggt ggcccatata aagaatggga cgagtatgaa
    26821 gaaaaagttg tcacaaataa tgatttggat gttggttttg aaatttacct taccattgtt
    26881 gattcttcac aaaaagaagt aattcagagc gaatcatctg agataattga tgataacatt
    26941 tccaataaag aagttacgga aactgaagct attgaaacta aaacaactga aactgaacat
    27001 attgaacaaa atattgttag tgacagtgtc gctgatatag taaacgagat taatctttca
    27061 gaaacatctc ctaagaaaaa acttcctgcc aataaaatca tattttcagc actgtatctt
    27121 ttcttagtct tttttggagt tgttggtatt ccaatcgctc cattccttgc agtccctttg
    27181 acagcttgga gtttgtataa actatacaaa ctattcagaa aataaaaaaa agccccacaa
    27241 tcgccctcgc caaagtttga ttgtgaagct tacccttata aaaaatcagc cattaaaaag
    27301 gcctcttttc tataccctat tttacaccat gaaaggggtg atgtcaatat tctcaatgtt
    27361 tagaccttgt ccagaagccg ataaacaagg agaatacaat gaaatataat aaaacaaaat
    27421 acccaaatat ctattactat gagactgcta aaggcaagcg ttactatgtc agacgttctt
    27481 ttttcttccg aggtaaaaaa agagaaaaaa gtaaaagtgg tttcacaact ctccctcaag
    27541 ctcgtgcagc cttggtagag cttgagcaac aaatccaaga acaagaatta ggtatcaata
    27601 cgaatctaac gcttgatcaa tattgggata tctattccga aaagagattg tcaacagggc
    27661 gctggaatga cacttcctac tacctcaatg acaatctcta taagaaccat atcaaggcaa
    27721 agtttggttc tatcctgctt aaaaatttgg atagaaatga gtatgaacta tttatcgctg
    27781 aaaagttgca gaaccatacc agatacactg ttcaaaccct caattccagc ttcatggcat
    27841 tgctgaatga tgccgtgaaa aatggtaatc tgctctcaaa tcgcttgaaa ggtgttttca
    27901 tcggccagag tgatatccct gctgcaaaca agaaagtgac tctcaaagag ttcaagactt
    27961 ggatagcaaa ggcagaagag attatgccaa aacaattcta cgctctgacc tatctgacaa
    28021 tttttggatt gagaagagga gaagtctttg gattgcgtcc aatggacatc actcagaacg
    28081 acagcggacg ggctatactg catcttagag acagtcgaag caaccagacc ttaaaaggga
    28141 aaggagggct taaaacgaag gattcagagc gatatgtctg ccttgatgat atcggaacag
    28201 acctgatcta ttatctgata gctgaagctt ctaagattaa gcgaaagtta ggaattatca
    28261 aggaacagca caaggattat ataactatca acgagaaagg tggtctcatc aatccaaatc
    28321 agctaaatag aaacttcaat ctagtgaatg aagcaacagg attgcatgta acacctcaca
    28381 tgatgcgcca cttcttcacg actcaaagca ttattgcagg ggttccgctt gaacaattaa
    28441 gccaggcgct ggggcataca aaggtttata tgacggatcg ttacaatcaa gtagaggacg
    28501 aacttgctga agcgacaaca gacctatttc ttagtcatat tcgctaaaaa agtccccgcc
    28561 aattccccga ccaaaatccg aaaaataccg aaaaatatcg aaaaattatt tttagaatag
    28621 tccccaaaag cctgaaatag agctaaaaaa ctccacctga ttcggtggag ttaagggaga
    28681 ttattatgaa aaagaaaagt ttaggatatt tgttacaaca agttaggagg tcttcttgta
    28741 actgtctata gtatacccga cctatcttaa acaaatctta aaaatctctt aggaccaaac
    28801 actttctaaa atatttgttt gttcacgacc aggacctact gagaaagtag aaatacgaac
    28861 gccaaccaat tcactcacac gacgaacata gttacgcgca ttctcaggaa gatcttccaa
    28921 attgcgaact ccggtaatat cttctgacca acctggcaac tcttcataga taggcttgca
    28981 acgtttcaat tgctcaagac tagctggata gtagtcaata cgttgaccgt caagatcata
    29041 ggccacacag attttcacag tatccaaacc gctcaaaaca tcaatagagt tcaaagaaag
    29101 gttagtaata ccagaaacac gacggctatg acgcatcaca actgagtcaa accaacctac
    29161 acgacgtgga cgaccagttg ttgtaccata ctcatgaccc acttcacgga tacgttctcc
    29221 cacttcatca aacaactcag ttgggaaagg accatctcct acacgactcg tataagcttt
    29281 acatacacct acaaccttgt caatcttgct tggaccgaca ccagaaccaa ttgtcacacc
    29341 accagctaca gggtttgatg acgtaacaaa tggataagta ccttggtcga tatctagcat
    29401 aacaccttgt gcaccttcaa aaagcacacg tttgccatta tcaagcgcat cattcaagat
    29461 aacagatgta tctatcacgt atttcttgat ttgttgacca tattcgtaat attcttcaaa
    29521 aatatcatcg aaaacaatcg ctttactgtc atacaatttt tcaaaaagac gattcttttc
    29581 agcaaggtta cgttctaaac gctcacggaa aatatcttta tctaaaagat ctgcaatacg
    29641 aattccaaca cgagcagcct tgtccatata agctggacca attcccttaa ttgtcgtacc
    29701 aatcttattg tcgcccttag cttcttcttg caagcgatcc aactcgatat gataaggcaa
    29761 aataacatgc gcacgatcag aaatacgcaa gttatcagtt gttacacctt cctcatgaag
    29821 atagctcaac tcttttacaa gagatttagg atttacaacc ataccattcc caatgacaga
    29881 tattttttca gggaagaaaa tcccagatgg aatcaagtgc aacttaaatt tcttaccgtc
    29941 aatcacaatc gtgtgaccag cattatcacc accttggtaa cgtgcaatca cttctgcatt
    30001 cgctgaaagg aagtctgtaa tcttcccttt accttcatca ccccattggg tacctacaac
    30061 aacaactgaa gtcataatct tgtctgagcc ctcaggctct tcctttctca catacatggc
    30121 aggactctca cctgcaatta tatcttacaa tttattataa taaaaaatcg cctttttatc
    30181 aagaagaaac aatagaaaga tttgctattt ccaactatta aaaaatgatt tagaaaaatt
    30241 actagctatt tactatcatc tttccataaa agagtaaatt agttcggaaa tttactaaaa
    30301 ttacctcaac aagaaataaa accccgattc attaccaatt tttcaagata caaacgataa
    30361 gcaacacgat aatggtaaac gataaaatcc ctacgacaac caatgccata tctcactaaa
    30421 taataaatta aaaatttaaa atgaacatgt tcccagtcaa aattatcacc aaatgtagga
    30481 ccatactctt cttcaatact atcatagaaa ttagccatct gctcataaat tttttgtaac
    30541 ataatcaaat actccttttc ttttttataa acttattcta acaaaaaatt ttacacattc
    30601 actatcaatt cctgaattgt taaaatacca gcctcaacaa gataaaaata ggaaaagttg
    30661 acaaaataga aacaaatttg ctacctaaat ttcaaacgat taaagttcta aaaagaccgc
    30721 cttaaaactt ttgggtaaat cctattagaa ctataatatt tatatatatg tattatggtt
    30781 ctgattttct agtataaaaa aattcaaact agaattcttc ttagaaaagg ccgttttaag
    30841 tgctatcatt gctcaaaaat ggaggtcgct gagacttcta tcgtcaagaa gaatcatcaa
    30901 attccttgta tcatcaacca aaagattgct cagaagctaa ttgaaaagac ttctatgacc
    30961 gacattgatc atcagttgtc tatttcaact tcaactgtca ttcgcaagat caataatttt
    31021 cactttgagc atgatttttc gcgtcttcct gagattatgt cctaggacgt tgaaacagtc
    31081 cggggagtga ctgtttcaat cgggagatgg agatgagctt tattgctcag gactttgata
    31141 aactcaatat cataactgtt cttgagagca gaacacaagc catcatccga aatcccatga
    31201 atacaaggct atcaagcgct actggaagct cattcaacaa gatagtcaga aactgagtga
    31261 taaacgattt tatcgcccta cttttcgtat gcacttgact aataaagaaa ttctagataa
    31321 acttttgagc tattccgaag acttgaaaca ccactataat ctctatcagc tcttgctttt
    31381 ccacctctgt ttcagacttt gtttaaaacc ttcctcaaag ataaagagaa aatcgtcaac
    31441 gcccttcaat taccttattc caacgccaaa ctggaagcca ccaataatct catcaaactt
    31501 atcaagcaca atgcctttgg ttttaggaac tttgaaaact tcaaaaaaga aaggacgaaa
    31561 tttgtccttt ctagatcttc gctttcttca acccactaca gttgacaaag aaccgaaaaa
    31621 tgtctcgcct ctaatatagt caattgaaac aagaacaaga gaaaagagcc tcgtaaaagg
    31681 tattgcaact tggtaatacc tttttgaggt tctttttgat ataagcccat gttttctcaa
    31741 taggattgta ctcaggtgag tagggaggaa gaggtaaaag tttatgccca aactcctcgc
    31801 ataaaagttc taacttaccc attctatgga atcttgcatt atccataata ataaccgatg
    31861 gtgtggttaa tgttggtaag agaaacttct gaaaccaagc ttcaaaaaag tcgctcgtca
    31921 ccatctcttc gtaagtcatt ggagcgatta actcaccatt tgttagacct gcaaccaaag
    31981 aaatcctctg atatcttctt ccagatactt tacctcttat taactgacct tttaatgagc
    32041 gaccatattc tcgataaaaa taagtatcga atcctgtttc atcaatctaa acaggtgcta
    32101 ggtgctttaa actattaaaa tttttaagaa ataaggctac tttttctggg tcttgttcat
    32161 agtaggtgtg gttctttttt tcgagtgtag cccatagctt tgagcgcata gtggatggta
    32221 gttggatgac agccaaattc agaagctatt tcagtcaaat aagcgtctgg attgtcagta
    32281 agatagtttt taagtctatc tctatcaacc tttcttggtt ttgttccttt tacttggtgg
    32341 tttagctctc ctgttttctc ttttagcttt aaccagccat aaatggtatt acgtgagatt
    32401 tggaaaacgt gtgacgcttc tgttatacta cctgttcgct cacaataaga gagaactttt
    32461 ttacgaaaat ctattgaata tgccataaaa agattatacc acattgtgta ctatttttgg
    32521 ttcattttac tataacacaa aatagattat tattacataa caaaaaagag gtctaaacct
    32581 cttaactcaa ttactccgcc agtaggactc gaacctacga catcatgatt aacagtcatg
    32641 cgctactacc aactgagcta tggcgga
//
LOCUS       DAVLTT010000019        27602 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLTT010000019 DAVLTT010000000
VERSION     DAVLTT010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27602
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.019"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(7..729)
                     /locus_tag="VYN15_000985"
     CDS             complement(7..729)
                     /locus_tag="VYN15_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1452326.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(1042..1272)
                     /locus_tag="VYN15_000986"
     CDS             complement(1042..1272)
                     /locus_tag="VYN15_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1452327.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            complement(1282..2523)
                     /locus_tag="VYN15_000987"
     CDS             complement(1282..2523)
                     /locus_tag="VYN15_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV1452328.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVIFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSLVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(2545..2697)
                     /locus_tag="VYN15_000988"
     CDS             complement(2545..2697)
                     /locus_tag="VYN15_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452329.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(2718..2996)
                     /locus_tag="VYN15_000989"
     CDS             complement(2718..2996)
                     /locus_tag="VYN15_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV1452330.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(2989..3252)
                     /locus_tag="VYN15_000990"
     CDS             complement(2989..3252)
                     /locus_tag="VYN15_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV1452331.1"
                     /translation="MSKMSMSIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(3354..7745)
                     /locus_tag="VYN15_000991"
     CDS             complement(3354..7745)
                     /locus_tag="VYN15_000991"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV1452332.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNAAFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFINKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMNVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(7849..9930)
                     /gene="fusA"
                     /locus_tag="VYN15_000992"
     CDS             complement(7849..9930)
                     /gene="fusA"
                     /locus_tag="VYN15_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV1452333.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(10354..10824)
                     /gene="rpsG"
                     /locus_tag="VYN15_000993"
     CDS             complement(10354..10824)
                     /gene="rpsG"
                     /locus_tag="VYN15_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV1452334.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDATNNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(10844..11257)
                     /gene="rpsL"
                     /locus_tag="VYN15_000994"
     CDS             complement(10844..11257)
                     /gene="rpsL"
                     /locus_tag="VYN15_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV1452335.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            11674..15537
                     /gene="spuA"
                     /locus_tag="VYN15_000995"
     CDS             11674..15537
                     /gene="spuA"
                     /locus_tag="VYN15_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV1452336.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESGISSPGNANASLEKTEEKPATEPP
                     TPAASPADPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQ
                     GLWTWDDVEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNL
                     TGDKSVEKLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVK
                     NPSSAQWPDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFT
                     DLKNHSQIFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKH
                     SNITNHLGNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDE
                     TYSYDGKLGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTW
                     KQTLDSTNKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVA
                     KAAFVDPAKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEA
                     FIEKLDYLKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSL
                     TGMYSSDPKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFM
                     DADGTPRTSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEA
                     YKAARALNPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGY
                     PNEGQPAFITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSI
                     KKDPSKAENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDK
                     VPNKSHLLRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKG
                     LIALRQSTDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVN
                     ADEKAREFNLGTAFAHLRNAEVLADENQAGSVKIANPKGLEWTEKGLKLNALTATVLR
                     VSQNGTSHESTAEEKPDSTPSKPEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENK
                     PSQATADSQAEQPAQEAQEASVKEAVRNESVENSSKENIPATPDKQAELPNTGIKNEN
                     KLLFAGISLLALLGLGFLLKNKKEN"
     gene            complement(15637..16686)
                     /locus_tag="VYN15_000996"
     CDS             complement(15637..16686)
                     /locus_tag="VYN15_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV1452337.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            16743..16820
                     /locus_tag="VYN15_000997"
                     /pseudo
     CDS             16743..16820
                     /locus_tag="VYN15_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(16958..18766)
                     /gene="glmS"
                     /locus_tag="VYN15_000998"
     CDS             complement(16958..18766)
                     /gene="glmS"
                     /locus_tag="VYN15_000998"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV1452338.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(18959..20338)
                     /gene="bglA"
                     /locus_tag="VYN15_000999"
     CDS             complement(18959..20338)
                     /gene="bglA"
                     /locus_tag="VYN15_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1452339.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            complement(20438..22291)
                     /locus_tag="VYN15_001000"
     CDS             complement(20438..22291)
                     /locus_tag="VYN15_001000"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV1452340.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(22304..23563)
                     /gene="rseP"
                     /locus_tag="VYN15_001001"
     CDS             complement(22304..23563)
                     /gene="rseP"
                     /locus_tag="VYN15_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV1452341.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTVLPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(23585..24388)
                     /locus_tag="VYN15_001002"
     CDS             complement(23585..24388)
                     /locus_tag="VYN15_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV1452342.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(24397..25155)
                     /locus_tag="VYN15_001003"
     CDS             complement(24397..25155)
                     /locus_tag="VYN15_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV1452343.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(25386..25958)
                     /locus_tag="VYN15_001004"
     CDS             complement(25386..25958)
                     /locus_tag="VYN15_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV1452344.1"
                     /translation="MNTVKNKQEILEAFRESPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(25939..26910)
                     /gene="ruvB"
                     /locus_tag="VYN15_001005"
     CDS             complement(25939..26910)
                     /gene="ruvB"
                     /locus_tag="VYN15_001005"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV1452345.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            27071..27163
                     /locus_tag="VYN15_001006"
     CDS             27071..27163
                     /locus_tag="VYN15_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV1452346.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
BASE COUNT         8051 a         6552 c         5257 g         7742 t
ORIGIN      
        1 actaaattaa ataatattag cgcggagaat ttctaattct tccttggtca agcgacgcca
       61 ttcccctcgt tccaggttct catctaatac taaagttccc atagtcaatc gttgcaagtc
      121 caccacttcc ttgccacagt agcccaccat acgcttgatc tgatgaaact tcccttctgc
      181 aatggtcaca cggatttggc tttgattctt ttctgtatct atggatacaa gctccagtat
      241 agcgggttga caggtaaagt ctttgagagg aataccctca gcaaatgtct ccacatcttc
      301 ttgggtcatg attcccttga cttgtgccag ataagtcttg tccacatgac gcttgggcga
      361 aagaagaaca tgagccagct gaccatcatt ggtcaagagc aaaagaccat gcgtgtcaat
      421 atccaagcgt cctactggga aaacttcctt actccgcgcc aagtcatcca acaagtccag
      481 aacggttctg tgcttgggat cctcagtcgc tgagataact cctttgggct tgttcatcat
      541 gtagtagaca aactcttcat actccaacac ttgcccatca aagcgaatct catctatttt
      601 ttcatcaatc tgcaatttag ctgatttttc ttttttacca tttacagtca cgcgcccagc
      661 cttgagcaag tttttgacct cagtccgact tcccaccgca caggcaacta aaaatttatc
      721 taatctcata gaactattat atcatatcaa aaggaggctg gtacaatgac caacctcctt
      781 ttcgtttcat actcttcaaa aatctcttca aaccgcgtca acgtcgcctt gccgtatata
      841 tgttactgac ttcgtcagtt ctatctgcaa cctcaaaaca gtgtttttag ctgacttcgt
      901 cagttctatc tgcaacctca aaacagtgtt tttagctgac ttcgtcagtt ctatctgcaa
      961 cctcaaagca gtgctttgag caacctgcgg ctagtttcct agtttgctct ttgattttca
     1021 ttgagtatca gatttaggaa attaacttcc tcgtctccaa aaaatagcta agacaatcat
     1081 ggcacctaaa acagctggga taatagctgt tcctgataaa actggccccc aagttccaaa
     1141 gagcaagtga cctagaaagg ctccgatcca accgagaaac atttttccaa aacatcccat
     1201 tcgctctcca cgattggtca tagcacctgc taaaaatccc actaggagac caacgaacat
     1261 acttcctaac atattatctc cttaatttgc ccaattccca ttacggaaaa gaggtacccg
     1321 cgttccatcc tcacgaatac catcgatatc catttggtta gaaccaatca taaagtctac
     1381 gtgaacatct gaacggttaa gccctgcagc ttcaagctcc tcttcgctca tctccgctcc
     1441 atcaacaagg ctagtcgcat aggctgcacc gatagccaag tggtttgacg cattttcatc
     1501 gaaaagggtg ttaaagaagg taatgcctga ctgagaaatt ggacttggat ctggtaccaa
     1561 ggcacattca cccaaggcac gcgcacccgc attttcaaag acaaggtctt tcataacctg
     1621 atcacccttc tcagcagtga tatctacgat ttgtccatcc ttaaagatca ccttaatgcc
     1681 ttcaatgata tttccgttgt agctaagcgg ttttgtagaa gtgacataac catctgcacg
     1741 acggaagtca ggcgctgtga agacctcttc tgtcggcata tttggcaaga atccttcgcc
     1801 ctgtgcattg acagcaccag ctgattccca aacgtggttc tttggcaaac caagtgttaa
     1861 atctgttcct ggcgctgtgt agtgaagggc tgaaaattgc tccttattaa gcatatcggc
     1921 cttgctcttg agaatggctg catgctcttc ccaggcctta acaggatctg cttcgtagac
     1981 acggcaagtt ttgaagattt ggtcccaaag gagatcgact gcttcttcgt cgctcgcagc
     2041 atttgggaag actttcttag cccactcaag tccagcagcg gctgctacag tccagctaac
     2101 cttgttagat tgagttgcga ttcgcattgg cttcatggca agtcccatag ctttagcaga
     2161 agctgaaagc ttgtcagcgt ccactccgtt caaggcacct ggatcagatg aacgaactcc
     2221 aagacggcta gccttgttct ccaagagata gttcatctca gcaatcttgt attctggcac
     2281 attgtccaaa cgctccatcg gggcatggag gaatttctca cggttaatca catcatctgt
     2341 ccactgaacg atgacctcat gcgcacccaa ggcataagct tctttcacga ttagatgtgc
     2401 caattcacgt tgctccacat caatagagag agccaaagtg tgaccaggtt gcacgttaat
     2461 tccgttcgca accaacaatt tcgcatattt ttctagattt tctttaaaat ttggtaaaac
     2521 catcctgttt tctcttttct atttttattt ttctttcaaa gcagaaaaga ttcctgctaa
     2581 agcaatagca cctgacaaga gtgctgtcga taaaagaatt gtacgatcag caagttctaa
     2641 ttgatattca aataccttct tagccggctt atcttccgca aatattctta gtttcatgag
     2701 aaccccctta aaatagatta aaataaatca ctgtgactgc ctgtcctcag caaatttaaa
     2761 atcaattccg acttatctac tttataaacc aaaagccaat ctggctgggt atggcattca
     2821 cgaactcctt gaaaatgctt ggatgccgtc aatgaatgat cacgatatct ggcaggatgt
     2881 tctttttctt gaaccagaaa attcaaaact tcttctaata attctgcctt caaaccacgc
     2941 ttcatagcca acttaaaatc ttttttaaac tgtttatgat aacgaatctt aagcacgtaa
     3001 gtcctccatc aaatctgaga ctgattcaaa agactggctc atattacgat tttggtctaa
     3061 atccgttaac acttggagca acttccgatt ttcgtctagt ctaacatcaa aaggtaatcc
     3121 ctgatattga attgcctgac gaaggaaaat attaatagct gttgtcatat ccattcccag
     3181 attactaaac acctgttggg cctgctcctt aacctcacta tccagacgga tgctcatact
     3241 catctttgac atactctcac cctctttcca tagactattt taacaaaaaa gaaagctaat
     3301 gtaaatctat tggatatacg ttagcctctt ctaatagatt attaagcaat tttttaaaac
     3361 aactcatcaa acaaactcaa ctggttatcc tctggcatat ttccaagaat acccatctca
     3421 tccatctttt caaccaaggt tgatgagagt ccaccacgct tgcgtagttc tgttttagag
     3481 aggaattctc cctcttcacg cgcccgcacc agttgcttgg caacgttctc tcccagacca
     3541 tccattgcta caaatggtgg gataagggta tccccgtcga tgaggaactc tgtcgcctga
     3601 ctacggtaga gatctaattt gccaaacttg aaacctcgtt cccacatctc attgacaatc
     3661 tcaagagttg tatagagatc gatttccaca ttagaggctt cattgttctt ccgtttttca
     3721 gagatttctt ccattctgcg cttgatggcc tccaagcccg cacccatggt cttgatatca
     3781 aaagccttag cacgaatgga gaagtaagca cagtagtaat aaataggatg gtgaaccttg
     3841 aagtaagcta cacgcaaggc catcataacg taggctgccg catgggcctt agggaacatg
     3901 tacttaattt tcccacagga ttcgatatac cactctggca ccttattagc cttcatggct
     3961 tcgatatagc catttctctc ctcttctgaa atctttagcc acaaaccctt acgtacccgt
     4021 tccataatgg taaaggccat cttaggttcc agacccgcat gcatgaggta aaccatgatg
     4081 tcgtcccgac aaccgataac agtcgatagg tccgctattc cttgcttaat cagatcctga
     4141 gcattcccca accaaacgtc agtaccgtgg gacagaccag acagctgaag caattccgca
     4201 aaggttgtcg gatgggtttc gtctaccatt ccacgtacga aatttgttcc aaactctgga
     4261 atccccaaca tacccgtagg cgttccaatt tgttcaggtg ttacccctag cacatcagtc
     4321 ccagaaaaga gtgccatcac gccttcgtca tccataggaa ttttattagg gtcaatacca
     4381 gacaaatcct gaagttttcg aatcatggtc ggatcatcat gtcccagtac atcgagtttg
     4441 aggacgttct catcgatatc gtggaagtta aagtgagtgg tctgccattc agccgtgaca
     4501 tcatctgctg gatactggac aggcgtaaaa tcgtagacat tcatgtagtt cggaataaca
     4561 acgattcccc ccgggtgttg gcctgttgtc cgcttgacac ccgccgctcc ttgagcgagg
     4621 cgttctactt ctgcatcacg ataaaacttg ccataatctc gctcgtaacc cttgacaaat
     4681 ccataggcag tcttggcagc taccgtacca accgttcccg cacggaaggc atattcttca
     4741 ccaaagatat cacgcacatc caagtgggcg ctaggctgat cttctcccga gaagttcaag
     4801 tcaatatcag gaaccttatc cccatcaaaa ccaaggaagg tctcaaacgg aatatcctgt
     4861 ccgtttttac tgagtttgtg accacagttt ggacagtcct tatggggcat atcaaatcct
     4921 gaaccgtacg aaccatctgt gataaactca ctgtactgac actgaccaca gacatagtga
     4981 ggagagagag gattgacctc cgtaatccca atcatggtcg caacgaaact agatccgaca
     5041 gacccacgag aaccaaccaa ataaccccgt tcattagaac gttgcaccag catctgcgat
     5101 gccagataaa tcacagcaaa tccattcccc agtatggatg ttaattcttt ttcaatccgc
     5161 aaatcaacaa tatctggcag cggatttcca taaatctcaa aagctttctt ataggtcaac
     5221 tcagcaactg tttcttcagc cttgttgatg aaaggcgtat acaagtcacc cttaacgact
     5281 tcaacgggtt caaatatttc tgccaaggca ttagtgtttt caataaccag tttacgagcc
     5341 agttcctctc ccaaaaaggc aaattcatcc aacatctcat tagtcgttcg aaaatgagcc
     5401 tttggaagtg gcgctggttg ggcatgttca ccatgaccga tagttcggtt aatcatcgca
     5461 ccctgtccca aactacggac gataatttca cgataaatct cttcttccgg ttcgatatag
     5521 tgaacatttc ccgtagccag aacaggcttg ccaaggcgat ctccaacctc tatcaaactc
     5581 ttgataatgg tctggagttc ctccatatcc ttgacctgct ctttggcaat caagggcgca
     5641 tagatagccg gtggcatgac ctcgataaag tcataatact tggccacctc aaccgccgca
     5701 tccacacctt gagaaacgac cacgtcaaaa acttcaccct ctgaacaggc tgaacctaaa
     5761 atcaagccct ctcgatgggc atctagaacc gttctcggaa tccgtggcac tccttcaaaa
     5821 tacttggtat tagacaagga aaccagctta aagatatttt ttagacctac ctgattcttg
     5881 acatagatgg tcgcatgctt gatccgagct tttttgtaag aatctggact gattagatca
     5941 atgttgagtc tagctaaatc ggtcacacca tgtttttctg ctacctcttt gataaagatg
     6001 aaaagcagac gaccagtcgc ttccgcatcg tagttggcca tgtggtgatg ttccaaggcc
     6061 acaccaaaac gcttggtcaa aggccccaaa ccatggcgtt tatactcagg atagaggttt
     6121 ctagcaaact ccagcgtatc aataactggc tgactaatct ttggaagacc atgacgctca
     6181 taattagcat tcataaagcc aacgtcaaag gcagcattgt gggcaactag gaccgtatcc
     6241 ttgcaaaatt cttggaattc ttgcaaaact tgttctagtg gtttggcatt tttgacatga
     6301 tcatctgtaa ttccagttaa ctctgtagta aaagctgaca agggatgccc aggattgata
     6361 aattcatcaa attcagcaat aacattcccc ttgtacatct tagaggccgc aacctgaatc
     6421 aagtcattat agatagctga aagtcccgtc gtttccacgt caaagaccac gtaggttgct
     6481 tctgataagt ccatctccac ttcgttatag acgataggga cacggtcctc cacgatattg
     6541 gcttctatcc catagatcag ctggattccc gctttcttag ccgccttata gccatgtgga
     6601 aaggactgga cattcccatg gtctgtgata gcaaccgcct tgtgtcccca cttagcagct
     6661 gttgcaacaa tctcttcgac ctctggcaaa gcatccatag tcgacatgtt agtatgagca
     6721 tgaaactcaa cccgacgctc accttctggc atcaaatcct tccgctcata gtgaacaact
     6781 tcctgcagat cctgtacgtt catagtcaaa tcgcgtgtga agttattcat ctccacattc
     6841 cctcgaactc ggagccaaga attcttcttg atgaggtcaa acttctgggc ctcttcctcg
     6901 tttttaaccc acttttgcat agaaaaactt gaagtatagt ccgtcatttt aaagttgatt
     6961 aaaacacgac ctgttctagt cactttttgc tccacatcaa aaacaacccc ttcaaatacc
     7021 agacgatttt cctctgtcgt cacttcgatc ataggagtaa tctccgcctt atccagcttg
     7081 ggtttagctg cagctttttt cgcttgaaaa tcaaagactg gtttctcttc cgctggagga
     7141 ggtgccatct gctccagttg ttccatagca cggagcgctt cctcattggc agcttgaaca
     7201 atctgctcat tttcagcatg aaaggcctct tcctgctctt gggtcaggac atcattcttc
     7261 tcgacttgac agttaaaagt tggaaaacca aacttttcaa gttgtttggc taaattagga
     7321 agatgattct tcttaaaatg ttccttatca atcgcttcag atccttcaat aaatagctga
     7381 ttaccctcag cacgaacttg caaattttga taaagggact taaaaccttg actagcacat
     7441 ggaccttcag agaaagcctc cctatagtag gactgcaaga gctgatttga aaattcttga
     7501 gaccgagcct taatttcaaa aacagcttta ttgcctgtct tagaaaattc ttcgctcaaa
     7561 cctttcttta attctaaaaa gatttcaatc ggtaaaatat tagaaaatac gaaatgaaac
     7621 tcccatacct tactaatttt atgaaccaca actcgctcaa tattggcctg tgctaaagca
     7681 ggagcctgtc tcatttcagc aggcatcccc aattgattca tcaaaatttc aaaactattt
     7741 gacattcatt ttcctcacat tattcttcta ctattttacc atatttagag gtattttcta
     7801 aagacaaaag gaagccacta agtgacttcc ttctagagtg aggacggatt agtcttcacc
     7861 tttatttttc ttaataattt cttcttgtac tgacttaggt acatcttcgt agtggtcaaa
     7921 taccatcatg aatgtaccac gtccttgaga tgcagaacga agaactgttg cgtaaccgaa
     7981 catttcagca agtggaacgt aagcacgaac gatttggctg ttaccgtgtg cttccatacc
     8041 atctacacgt ccacgacgag cagttacgtg acccataaca tcaccaaggt tttcttctgg
     8101 aacagtgatt gttacaagca tcattggttc aaggatagct ggttgtgctg atttagcagc
     8161 ttctttaagg gaaagtgaag ccgcaatctt gaaggcagtt tcagatgagt cgacatcgtg
     8221 atatgaacca tcataaagct tagctttaac gtcaaccatt gggtaacctg caagaacacc
     8281 gttagccata gattctacca aacctttttc aaccgctggg ataaattcac gaggaaccac
     8341 accaccgacg attgcgtttt cgaattcgaa tcctttacct tcttcgtttg gagtaaattc
     8401 aatccacaca tcaccgaatt gacctttacc accagactga cgtttgaaga atccacgtgc
     8461 ttgagtagaa gcgcggaatg tttcacggta agatacttga ggagcaccta cgttcgcttc
     8521 aactttgaac tcacgacgca tacgatcaac aaggacgtca aggtgaagtt cacccatacc
     8581 tgagataact gtttcaccag tttcaacgtt tgtttcaacg cggaatgttg gatcttcttc
     8641 agccaatttt tgaagggcga tacccatctt gtcttggtca gctttagatt ttggctcaac
     8701 catcaattgg ataactggtt ctggaacgtt gattgactca aggatgattt tagctttttc
     8761 atctgtcaat gagtcaccag ttgtagtatc tttcaaacca acggcagcag cgatatcacc
     8821 tgagtaaaca gtgtcgattt cttgacggct gttagcgtgc atttgaagga tacgtccgat
     8881 acgttcacgt ttacctttag aagtattcaa tacgtatgaa cctgattgaa gaacacctga
     8941 gtaaacacgg aagaatgtca aacgacctac gaatgggtca gtcatgatct tgaaggcaag
     9001 agctgcaaat ggctcttcgt cagatgctgg acgaatttct tcagcgtctg tatctgggtt
     9061 aatacctttg attgctggga tgtcaagtgg gcttggaagg tagtcgataa ccgcatcaag
     9121 catcaattga acacctttgt ttttgaaggc tgaaccacac aatactggga agaattcaac
     9181 gttgatagtc gctttacgga taccagcttt caattcttcg ttagtgattt cttcaccttc
     9241 gaggtatttc atcatcaatt cttcgtcagt ttcagcaact gcttcaatca atttttcacg
     9301 gtattcttga gcttggtcaa ggtattcagc tgggatgtct tcttcaagga tatccgtacc
     9361 aaggtcgtta gtatagattt cagctttcat cttgatcaag tcaatgatac cacggaagtc
     9421 atcttcagaa ccgattggca attggattgg gtgtgcattt gcttgaagac gatcgtgaag
     9481 tgtgcttaca gagtaaagga agtcagcacc gattttgtcc attttgttgg caaatacgat
     9541 acgtggaact ccgtactcag tcgcttgacg ccaaactgtt tcagtttgag gctcaacacc
     9601 tgattgtgag tcaagaacgg taaccgcacc atccaataca cgaagagaac gttgtacttc
     9661 gattgtgaag tccacgtgtc ctggtgtgtc gatgatgttt acgcggtggt tgttccattg
     9721 agctgttgtc gcagcagatg tgatcgtgat accacgttct tgctcttgct ccatccagtc
     9781 catttgtgac gcaccttcgt gagtttcacc gattttgtgg attttaccag tgtagtaaag
     9841 aatacgctca gtagttgttg ttttaccggc atcgacgtga gccatgatac cgatattacg
     9901 agttttttca agtgaaaatt cgcgtgccat gaggtttgtt tctcctattt atttttgatt
     9961 tctattctat tataacacga ttttaataaa aacggatagg caggacctac ccgttctcaa
    10021 tgttttcatg ctattgttgg tttcaactta cgagatggta agctgagtta tagctaatac
    10081 taatcgattt agctaatttg aacccgggct aaagttagtt agccgatgtg agctggaacg
    10141 agatgccgcg tgaaaaagat aaaactcctt gtattcgtcg aatactgcgt cagtttccta
    10201 ttttcacctt gcatccttac cgttcctagc atcatgattt agttgagctc aagctaaaag
    10261 tctggagaaa agatgaatct cattggttgc aaccgcaacc cgcttcgatt ccctattttc
    10321 tctgggactt tcttaacgct ttcgcatcct atcttaccaa cggaagtgtg cgaatgcacg
    10381 gttagcttca gccatacggt gagtgtcttc acgtttctta acagctgcac cagtgttgtt
    10441 agtagcatcc aagatttctt ttgcaagacg gtcttgcatt gtgtgttcac cacgaagacg
    10501 agcgattgtt accaaccaac gaagtccaag tgttgtacga cgttctggac gaacttcaac
    10561 tgggacttgg tagttagaac caccaacacg acgtgcacgt acttcaagta caggcatgat
    10621 gttttccata gctgtttcaa atacttcaag tgcatcgttg ccagtagctt ctttgatttg
    10681 ctcaaaagca ccgtaaacga ttgaagcagc agtaccacgt ttaccatcaa gcataacgcg
    10741 gttgataaga cgagtaacta gttgtgaatt gtatagcgga tctggcaata cgtcacgttt
    10801 tggagctcta tttttacgac tcatttctct ttatcccctt cccttatgct tttggacgtt
    10861 tagtaccgta tttagaacgg ccttgtttac gatcgttaac acctgcagta tcaagtgcac
    10921 cacggacgat atggtaacgt acccctggaa ggtcttttac acgtccaccg cgaagaagca
    10981 ccacgctgtg ctcttgcaag ttgtgtccga tacctgggat gtaggcagta acttcgataa
    11041 ggttgctcaa acgtacacga gcgaatttac gaagggctga gttaggtttt ttaggtgtca
    11101 ttgttccaac acgagttgca acaccacgtt tttgtggtga agaaacgttt gtttgaactt
    11161 ttttatgact attgtaacca acgttcaaag ctggtgattt agatttttct acttttgatt
    11221 tacgcggttt gcgaaccaat tggttaattg taggcatcta cattctcctg tattttttta
    11281 tttttggtga tgatacactt ggtgacagat atcatctgtg tgtacttttg caacatttgt
    11341 cagcacgtcc ctgtacactc ttgagagacc aaaagtaaaa agtaccgtct attattgtaa
    11401 caaaattttc ccttgcttgt caagatattt ttctttttta ttggtaatgt tagagatcaa
    11461 tttctgaata aaaatagctg ggaacacatc atcttcctaa taatacggct tgacttatgt
    11521 gacattttta tctccgtcat ttatactgat atataaaata gtacagaaaa cttctcaaaa
    11581 gtaagaattt ttttcacaaa tcaaagaaaa cgcttgcata ttgttttact acatgctata
    11641 ctgatataga aatttattga ttggagaatc attatgagaa aaacaccatc tcacactgag
    11701 aaaaaaatgg tctacagcat ccgttccctc aaaaatggga ctggttctgt ccttatcggc
    11761 gcaagccttg tcttgcttgc catggctaca ccaactatct catccgacga aagtacacca
    11821 accactaacg aacccaacaa cagaaataca accacccttg cccaacctct tactgataca
    11881 gcagctggct ctggtaagaa cgaaagtggt atttcttcac ctggaaatgc aaacgcttcc
    11941 ctagagaaaa cagaagaaaa acctgcaaca gagccaccaa ctcctgctgc aagcccagcc
    12001 gatccagcac cacaaactgg acaagatcgt tcaagtgagc caactacttc tactagtcca
    12061 gtaacaactg aaactaaggc agaagagccc atcgaagata actacttccg tatccatgtc
    12121 aaaaaacttc ctgaagaaaa caaggatgct caaggactat ggacttggga cgatgttgaa
    12181 aaaccatctg aaaactggcc aaacggagct ttgtccttca aggatgccaa gaaagatgac
    12241 tacggctatt acctagatgt caaattaaag ggagaacaag ccaagaaaat tagcttcctc
    12301 atcaacaata cagctggaaa aaatctaacc ggcgataaat ctgtagaaaa actagttcca
    12361 aaaatgaacg aagcttggtt agaccaagat tacaaggttt tctcttacga gccacagcct
    12421 gcaggaactg ttcgcgtcaa ctactaccgc acagatggca actatgacaa gaaatctctc
    12481 tggtactggg gagatgtgaa aaatccaagt agcgctcaat ggcctgacgg aacagacttt
    12541 acggctacag gcaaatatgg ccgctatatc gacattcctc ttaatgaagc cgcaagagaa
    12601 tttggatttt tattactaga tgagagcaaa caaggagacg acgtgaaaat ccgtaaagaa
    12661 aattataagt tcacagattt gaaaaatcat agccaaattt tcctaaaaga cgatgatgaa
    12721 tcgatttaca caaatccata ctatgtccat gatatccgta tgacaggagc ccaacacgta
    12781 ggcacttcta gcattgaaag tagcttttca acacttgtcg gtgctaaaaa agaagatatc
    12841 ctcaaacact ccaacatcac taatcaccta ggaaacaagg taactattac cgatgttgca
    12901 atcgatgaag ctggtaagaa agtgacctac agcggagatt tctctgacac aaaacatcct
    12961 tatactgtta gctacaattc cgaccaattc actaccaaaa caagctggca cctgaaagat
    13021 gagacataca gctatgatgg caaactggga gctgacctaa aagaagaagg aaaacaagtt
    13081 gatttgaccc tttggtcacc aagtgctgat aaggtttctg ttgttgtcta cgacaagaat
    13141 gaccctgaca aagtagttgg aactgtcgct ctcgaaaaag gggaaagagg aacttggaaa
    13201 caaactctag acagcacaaa caaactcgga atcacagatt tcactggcta ctattatcaa
    13261 taccaaatcg agcgtcaagg taaaactgtt cttgcactcg atccttacgc taaatctctt
    13321 gctgcttgga atagcgacga tgccaagatt gacgatgccc ataaagtggc taaagccgcc
    13381 tttgtagatc cagctaaact cggacctcaa gacttgactt atggtaagat tcacaatttc
    13441 aagactcgtg aagacgccgt tatctacgaa gctcatgtgc gtgacttcac ttcagatcct
    13501 gccattgcaa aagacttgac caaaccattt gggacttttg aagccttcat tgaaaaacta
    13561 gactatctca aagacttggg tgtaacccat atccagctcc ttccagtctt gtcttactac
    13621 tttgtcaatg aattgaaaaa ccatgaacgc ttgtctgact atgcttcaag caacagcaac
    13681 tacaactggg gatatgaccc tcaaaactac ttctccttga ctggtatgta ctcaagcgat
    13741 cctaagaatc cagaaaaacg aatcgcagaa tttaaaaacc tcatcaacga aatccacaaa
    13801 cgtggtatgg gagctatcct agatgtcgtt tataaccaca cagccaaagt cgatatcttt
    13861 gaagacctag agccaaacta ctaccacttt atggatgccg atggcacacc tcgaactagc
    13921 tttggtggtg gacgcttggg gacaacccac catatgacca aacggctcct agttgactct
    13981 atcaaatacc tagttgatac ctacaaagtg gatggcttcc gcttcgatat gatgggagac
    14041 catgacgccg cttctatcga agaagcttac aaggctgcac gcgccctcaa tccaaacctc
    14101 atcatgcttg gtgaaggttg gagaacctat gccggtgatg aaaacatgcc tactaaagct
    14161 gctgaccaag attggatgaa acataccgat actgtcgctg tcttttcaga tgacatccgt
    14221 aacaacctca aatctggtta tccaaacgaa ggtcaacctg cctttatcac aggtggcaag
    14281 cgtgatgtca acaccatctt taaaaatctc attgctcaac caactaactt tgaagctgac
    14341 agccctggag atgtcatcca atacatagca gcccatgata acttgaccct ctttgacatc
    14401 attgcccagt ctatcaaaaa agacccaagc aaggctgaga actatgctga aatccaccgt
    14461 cgtttacgac ttggaaatct catggtcttg acagctcaag gaactccatt tatccactcc
    14521 ggtcaggaat atggacgtac taaacaattc cgtgacccag cctacaagac tccagtagca
    14581 gaggataagg ttccaaacaa atctcacttg ttgcgtgata aggacggcaa cccatttgac
    14641 tatccttact tcatccatga ttcttacgat tctagcgacg cagtcaacaa gtttgactgg
    14701 actaaggcta cagatggtaa agcttatcct gaaaatgtca agagccgtga ctatatgaaa
    14761 ggtttgattg cccttcgtca atctacagat gccttccgac ttaagagtct ccaagatatc
    14821 aaagaccgtg tccacctcat cactgtccca ggccaaaatg gtgtggaaaa agaggatgta
    14881 gtgattggct accaaatcac tgctccaaac ggcgatatct acgcagtctt tgtcaatgcg
    14941 gatgaaaaag ctcgcgaatt taatttggga actgcctttg cacatctaag aaatgcggaa
    15001 gttttggcag atgaaaacca agcaggatca gtcaaaattg ccaacccgaa aggacttgaa
    15061 tggactgaaa aaggcttgaa attgaatgcc cttacagcta ctgttcttcg agtctctcaa
    15121 aatggaacta gccatgagtc aactgcagaa gagaaaccag actcaacccc ttccaagcct
    15181 gaacatcaaa atgaagcttc tcaccctgca catcaagacc cagctccaga agctagacct
    15241 gattctacta aaccagatgc caaagtagct gatgcggaaa ataaacctag ccaagctaca
    15301 gctgattcac aagctgaaca accagcacaa gaagcacaag aagcatctgt aaaagaagcg
    15361 gttcgaaacg aatcggtaga aaactctagc aaggaaaata tacctgcaac cccagataaa
    15421 caagctgaac ttccaaatac aggaatcaaa aacgaaaaca aactcctatt tgcaggaatc
    15481 agcctccttg cgctccttgg tctcggtttc ttactaaaaa ataaaaaaga gaactaaact
    15541 agccctccta tagaaaaatc ccccaagcat tatagctcgg gggattaatt ttcgtacaat
    15601 atttgttgtc ctaataaact tgattaggat tttttattaa gcctctttca tagcaaaata
    15661 agctcgtact ttgggtgcaa cttgtgttcc gaagagttca atagctctca gaacctggtc
    15721 atgaggcata gaaccaagcg gtagatgaag catgaagcgg tccaatccta aatcctctat
    15781 catgcgaatc aatttttcgg ccacctgatc tggattgcca acaaacatgg cgccatttgg
    15841 ccctacctgc tccaaatatt gctcataacg caattcctgc cagtgcggac ggtctttgga
    15901 aatagcatcc accacttgct tagtcggatg gaaataatct ttcaccgcct gctcaccatc
    15961 ttccgcaatc cacccccaag aatgggctcc cactttcaag tctttgtcag catgacccgc
    16021 ttcgcttcca atctcacgat aagcctgaat caacttttta aaataacgtg gattaccacc
    16081 aataatagca tatacaatcg gtagaccagc ctgagcaatc ttcactgttg attcgacatg
    16141 accacctgta gctatccaca agggcaattt gtcctgaact ggacgaggat aaacttcttt
    16201 accagcaatc gtttgagtca atcgaccttg ccagtctaac ttggtctttt cattgactaa
    16261 ctgaagcaag tctaatttct catcaaaaag agagtcgtag tctttcaagt cataaccaaa
    16321 cagagggaaa gattccgtga aagagcccct tccagccata atctccgctc gtccatttga
    16381 caaagcatcg atagtggcat actgttggaa caaacgaatc gggtccatgc ttgacagaat
    16441 gctgactgca ctggtcaaac ggattttctt ggtattgact gccccagcgg ccagaacaat
    16501 ctctggggct gatactgcaa aatccgcccg atggtgctca ccaatcccat atacatccaa
    16561 accaaccttg tcagccagct caatctctgc caccaactgg cgaatgcgtt cagcatgact
    16621 gtaagtttgt ccagtccctt caagctccgt tatttcccca aatgttgaaa ttcccaattc
    16681 taccattgtg attctcctta tctatctctg tacttcaatt tgaaaaatta ttctaatact
    16741 caatgaaaat caaagagcaa actaggaagc tagctgcagg ctgctcaaaa cagtgttttg
    16801 aggttgtgga tagaactgac gaagtcagta accataccta cggcaaggcg acgttgacgt
    16861 ggtttgaaga gattttcgaa gagtataaca cgaatcttga gtacaagcaa ccaatttgct
    16921 cacaagaaaa aggcctagat aactagactt ttttagctta ttctaccgtt actgacttgg
    16981 caaggttacg tggtttgtcc acatcgaggc cacggtggag ggttgcaaag taagcgacta
    17041 attgcgttgg tacgaccatt gaaattggtg agaggtatgg atgtacggtc gtaaggacga
    17101 tatcgtcggt atctttggct acattctctt ctgcgatagt gaggactttg gcaccacggg
    17161 ctgcgacctc ttggatattt ccacgagtat gattggcaag aactggatct gacaagagag
    17221 ccaaaacagg cgttccttct tcaatcaagg caatggttcc gtgcttgagt tctcctgcag
    17281 caaagccttc acactggata taagaaatct ctttgagttt gagacttgct tccatggcta
    17341 cgtagtaatc ttgaccacgt ccgatgtaaa aggcgttacg agttgtttca agaagttcac
    17401 gaaccttggc ttcaatggtt tctttctctg aaagagttga ttcgatagac tgagctacga
    17461 ttgacaattc atgaaccagg tcaaaggctt gcgctttagc attaccattt gcttctccga
    17521 ctgcttttgc aaggaaggca agggctgcga tttgcgctgt ataggcttta gttgatgcca
    17581 cggcaatttc aggacctgcg tgaaggagca tggtatagtt ggcttcacgt gagagggttg
    17641 aacctggaac gtttgtcact gttaagcttg gaattcccat ttcattagcc ttgaccaaaa
    17701 cttgacgact atccgctgtt tcaccagatt ggctgataaa gatgaagagt ggtttcttgc
    17761 tgagaagtgg cataccgtag ccccactcag atgagattcc aagttcaact ggtgtatctg
    17821 tcaattcttc caacattttc ttagaagcaa atcctgcatg gtaagatgtt ccagctgcaa
    17881 ggatgtagat gcggtctgcg tcttgaacag ccttaatgat atctgggtct acgacaactt
    17941 gaccagcctc atctgtgtag gcttggatga gtttccgcat aacagttggt tgctcgtcaa
    18001 tttccttgag catgtagtaa gggtaagttc ccttaccgat atctgacaag tcaagttcag
    18061 cagtgtagct agcacgctca cgacgatttc catcatagtc ttgaacttcc acactatcag
    18121 ccttgacgat taccaactct tggtcatgga tttccatgta ttggttagtt tcacgaatca
    18181 tagccatggc gtctgagcag accatgttat agccttctcc aagaccaatc aaaagtggtg
    18241 atttattttt agctacgtag atgacttcag gatcttgtga gtcaaccaag gcaaaggcat
    18301 aagaaccacg gatgatgtga agggcttttt tgaaggcttc aagaactgag agcccttctt
    18361 cttccgcaaa ttttccaatc aaatgaacgg ctatttcagt atctgtctgc cccttgaagt
    18421 ggtgacctgc aaggtattct tccttgattt caagatagtt ctcaatcacc ccattatgca
    18481 ccaagacaaa acgttctgtc tcagagcggt gtgggtgagc attgtcctca gttggttttc
    18541 cgtgagtagc ccaacgagta tgtccgatac cagttgttcc ctcaacacca gctgtcttgg
    18601 cagacaattc tgcaatacga ccaacagcct tcaccaaatg gttatcagca ccatctagga
    18661 caaaaattcc cgcagaatca tagccacggt attcaagctt ttcaagccct tgaatcaaaa
    18721 tatcagttgc atttgtgttt ccaacaacac caacaattcc acacatagta tatacgacac
    18781 aggcaagctg tgctttctcc ttaaaattgg tatagtctaa ttcatctttt atagaatcag
    18841 caaaaacagt atatacttgt ttctttcact tgtcaagagt aaaaattggt atagttcaaa
    18901 ttaagctcct gtaagcataa aaactctgac cgattgggat aatcagtcag agtccttttt
    18961 aaaatccatt attatcgctt aattctttga accagtggcc tgatttcttc agacgacgtt
    19021 cttgcgtttc caagtctaat tcgaccaaac catagcgatt tttatagctg ttgagccatg
    19081 accagcagtc aataaaggtc caaatcaagt agcccttaca gttggcacca tcttcaatgg
    19141 cacggtgaag ttcacgaaga tgacctttta caaagtcaat acggtaatca tcttgaatca
    19201 ttccatcttg acggaatttt tcttcccctt caacacccat accattctca gtcaacatcc
    19261 actcaatatt gccataattt tccttgatat tttgggcgat gtcataaatc ccttgctcat
    19321 aaatctccca accacggtga gaattgattt tacgtccagg catcacataa ggctcgtaaa
    19381 aatgttctgg taagagtgga ctatctggat gcttagcaaa tcgaggagcc ataacacgca
    19441 aaggttgata gtagttcaca ccaaggaagt ccaccgtatt atcacgaatg agttccaact
    19501 cttcctctgt agcatcaggt aaaagaccgt gttcatgcaa gatttctacc aactcctgtg
    19561 gataagtccc caagacagat ggatctaaga aagattgggc ctgaaaaagg gccgcaatac
    19621 gagctgcctt gacatcagca ggatgctggc tacgtggata agccggtgtc aagttgagga
    19681 caatcccaat cttggaatca ggcaaaagtt catggcaagc cttaacagcc cggctgctgg
    19741 ccaattgtgt atgataggct accttaacag ctgcctctgc atccacctta tgtggataat
    19801 gggcatcata aaaataacca aattctacag gaacgatggg ctcgttaaag gtaatccatt
    19861 gatccactaa atctccataa gtctcaaaac aaaaacgagc atagtcttca taggctgaga
    19921 ctgtcgcctt attttcccaa ccatcaccat cctcttgaag ggcaaaaggt aaatcaaaat
    19981 gatagagatt gactaacaga cgaattcctt tagccttaat agcctcaaag accttacgat
    20041 aaaaatccac accttgaggg ttgactttcc cacagccttg tggaaaaatc cgtgaccact
    20101 gaatagaagt ccgaaagact gtgtgaccag tctctaacaa aagctcaata tcccgctccc
    20161 aattttcata aaaagtcgat gtcttatctg aaccaatccc attatagtaa cgatttggct
    20221 ccacttggaa ccagtaatcc cagagattgt ctcccttacc gtcaccagct acacgtcctt
    20281 ctgtctgcgg tccagaagta gaggatcccc agacaaaatc ctttggaaat cttagcataa
    20341 catttacctc tttatctact catttctccc attatacaga aaaaacaagg taaaaactag
    20401 ttacattttt tccttgtttt tcttctgatt atagttttta tttcttgctt aggatttcaa
    20461 gcgtttcaag cacgttatct gcatgaacct caatggtgtc accagttgcc ttgatcttaa
    20521 cttctacaat gccatcggcc gcttttttac caacagtgat acggattgga agaccaatca
    20581 agtcactatc gctaaattta acaccgacac gttcgttacg gtcatctgtc aagacttcat
    20641 aaccagctcc catcaagctt gcttcaagtt tttctgtcaa ggcttgcgct tcttcatcct
    20701 tgacattaac agtaatcaaa tgcacatcaa atggtgccaa ttctttaggg aaattgattc
    20761 cccaagcgta acggtattca ccttttggcg ttttgttaac aaagaggcga gcgtgttgct
    20821 ccatcactgc tgaaagaaga cggctgacac cgataccgta acatcccatg atgattggca
    20881 cagcacgacc attttcatcc aagacatctg ctcccatgct tgctgaatag cgagttccga
    20941 gtttgaaaat atgaccgatc tcaataccac gcgcaaagtt aaggacacct tgtccatctg
    21001 gggaaatttc accctcacga acttcacgga tatccacata ttctgcagta aaatcacggc
    21061 ctgggttcac accagtcaag tggtagccat cttcgttagc accgacaact gcattgcgaa
    21121 catcttgcac cttacgatct gcaataattt taatattctc tggcaaacca actggtccaa
    21181 gtgaaccaaa tcctgcttga acaacattcg ccacttcttc ttcgctagca acgtcaaaga
    21241 aatctgctcc caagtgattt ttcaacttga cttcgttgag ttggtcattt ccaactagaa
    21301 gggctgcaac aagctcacca tctgcaatgt agaagagggt tttaatcgtt tgttcttctg
    21361 gaacattgag gaaagctgca acttcatcaa ttgatttaac atctggcgtt gcaacacgag
    21421 taacttcttc ttcagcgaca acacggttgc ttggtttgta ctcgtttgtt gccatttcta
    21481 agttagctgc atagctagac tcacttgagt aagcaatggt atcttcacca gagactatcc
    21541 atttgagcaa ttctgccttg atttcttctt gcacttctgc aggaatttcg tcaaatgagg
    21601 caactgactt gtccaagaca acccagcggt caaggtctgt acgagcagat gtaatggcca
    21661 taaattcttg gctatcctta ccacccatgg ctccaccgtc accaataata gccttgaagt
    21721 ctaaaccact acgagtgaaa atacgctcat aagctgcttt gtactcatca taaacactat
    21781 ccaaactatc atagttagcg tggaaactat aagcatcctt catgataaac tcacgtgtac
    21841 gaagaagtcc attacgcggg cgtttttcat cacgatactt gggctgaatt tgataaaggt
    21901 tgagtggcaa ttgcttgtaa gatttaacag aatcacggac aatagctgta aaggtttctt
    21961 cgtgagttgg acctaagata aagtctgatt tttcacggtt ttttagtttg taaaggtctt
    22021 caccataggt ttcgtaacga cctgattcac gccacaattc tgcactaaga agggctggag
    22081 ccaacatctc aacagcacca atcttttcga attcttggcg catgatgttt ttagcttttt
    22141 caatcacacg gttggcaagt ggtagataag aataaacacc tgctgaaact tggcgaacat
    22201 aaccagcacg caacataaga gcatggctga taacttgagc atcgcttggc atttcgcgaa
    22261 gcgttgggat aggcatttta ctttgtttca taatattcct cgattatcta aaaaagagtc
    22321 gcataatgtc attccaagtc acagcaatca tcaagacaac catgatgacc actccggcca
    22381 aggtgacata ggtttcaatt tcttgtttca atggtttgcg gcggatggct tctaggatat
    22441 tgagcacaat cttaccacca tccaaggctg gaatcggaat aagattaaaa atcccaatat
    22501 tgatggaaat cattgccaag aagtacaaga tattttcaat tccattttta gcagcatcac
    22561 tacttgcctt aaagatagca acaggtccac ccaacttgtt caaatctggt tggaaaatca
    22621 gatttttcag agctgagaga attcggagag ctgagtcagc agcagttgta aaaccaccta
    22681 caaacatgga tagaaaatct gacttaaccc ccggttgaac acctagaagg taacgacctt
    22741 gactatcttt gggtgtaaca gtgacttgtt tgtcactccc cttttcagaa atagtcacat
    22801 ccaaagtcgg tgccgtctta tctttggttt ctgtttccac agcttggatc aagctttccc
    22861 agttgctaac ctcatgtgag ccaatcttgg taatttgtgc cgtttctggt actcctacct
    22921 tggccaaggc accttggggc atgatatgga actgattggt atcaacatct ctgacaccac
    22981 cctgcataaa gattaaaacc caaaaaacaa cgacacctaa gataaaattg ttcataggac
    23041 ctgcaaaatt ggtaatcagt ttgccccaga tagtcgcatt ttgatattga acatctaaag
    23101 gtgcaatccg aacctcagta ccatctgctt ccacaaccgt tgcatcgtga tccactgcaa
    23161 atgttttttc ttcttccaga accaatcctt tgataaagag cttgtcttca aaatcaaact
    23221 gggtcacctg catagggagg actgtttgat ccaatttttt acctgagaga ttgatgcgtt
    23281 taaccttacc atcatcagca agtgtcaaac taacaggcgt tcctgtcttg atttcagttg
    23341 tatcatcacc ccaaccggcc atgcggacat agccacccag aggcaagatt cgaatggtat
    23401 aggccgttcc atccttgcca atgtgagcaa aaattttagg tcccataccg atggcaaatt
    23461 cacgtactaa aatccctgat ttcttggcaa agtagaagtg cccgaactcg tgcaccacta
    23521 caataatccc aaaaaccaga ataaaggtta aaattccaag catagtgttt cctccgtctt
    23581 ttgattaaaa gagtccaaat aagtgcatga ttggaaatac aagcaacata ctatcgaaac
    23641 gatccaaaac accaccatgt ccagggataa atttcccaga atccttaaca ccaaaatgac
    23701 gtttgatcga actttctagt aaatcaccaa attgtccagc aatgctaaag aaaatagcaa
    23761 agactgacat cttgtaaatt ccatatggaa gagcaactgt actgtcaact atcataaaga
    23821 taatggttac taaaattgct cctaaaatac cacccaaggc accctcaagg gttttattag
    23881 gcgataccct tggtgctaac tttcgtttcc catagttcat cccaacaaga taggcaccac
    23941 tgtctgtcgc ccagacgata cacaaggcta agagagcctt gtccaaacct gcaacacgag
    24001 catctagtaa agcattaaat ccaaagccca cgtagaagct catagcaaga gggaaaaccg
    24061 catcctcaat cgtataagac ttgctaaaaa cggtcgttcc taacatgatt gaaatcaaaa
    24121 cactataggc aaccacattc ccatcaactg gcaaaaaagt caggtaattc tccaagggaa
    24181 tggtcaatgc aaaggttgca aagagggtca agaggccctc catcgtcatg gtctctagac
    24241 ctctcatctt caaaagttca tgcatggcta gcatggctat gattccgatt gctatctgaa
    24301 gcaagaggcc cccaatcatt aaaattggta ggaaaatagc cagggcaatc cctgcaaaca
    24361 aggttctttt ctgtaaatcc tgggtcatat ttcctcctaa actcctccaa atcggcgatg
    24421 acgacgatta taggcaagaa tagcttcctg caaggccgct tcgtcaaaat caggccataa
    24481 ggtgtccgta aaataaagct cactataggc tccctgccat ggaaggaaat tgctcaaacg
    24541 taattctcca ctagtacgga taatcaagtc tgggtctcgt aagtccttag gcaaatgctg
    24601 agtaaagaga tagttaccaa tcaattcctc tgtgatgtca cctgggttga ttttggcatc
    24661 taaaacatcc tgggaaatca acttaagcgc ctgtgtaatc tcagcacgtc caccatagtt
    24721 aagagcaaaa ttaagaatca atcctgtgtt gttcttagtc aattcctcag ccttggttaa
    24781 agcttcaaag gtttgcttag gcaggcggtc tgtctcccca atcatttgaa tcttaacatt
    24841 attcgcatgt agttccggga cataattatc ataaaactct actggcaagt tcatgataaa
    24901 cttgacttcc tgatctggac gggtccagtt ttccgtagaa aaagcataga ccgtaataac
    24961 cttgacgccc agtttgttgg ctgccttggt cacggtttgc aatgcttcca tgcccgcctt
    25021 atgtccaaaa actcgcggtt gcatacgttt tttagcccaa cggccattgc catccatgat
    25081 gatgccgata tgagcaggaa cctgtgtcgg aacctctact tccacagcct tatctttctt
    25141 aaaaaatcca aacatgatct tattcctatt caaaaatcta tcgtttcatt ataccatatt
    25201 tccccatttt cttctatcac taagctattt attctcaggc accaagccca tttttcaaaa
    25261 aaataagccg cctgattggg cgactttatt tttataggga gattattatg aaaaagtttt
    25321 aggagtttaa gttaaggtct tcttaactta tgaacttagt gtacactccc tagcttaaag
    25381 tttccttaag tatttttaaa aatcaaattt ttccatttct cctgccaatt tttcttggat
    25441 aaacgtgttt gatagagttc cattcggtct tcattttcta agaaatgagg agttggacga
    25501 acttgaaaat tcaaaatatc ctccaaacca taaggtacat agagttcaaa atctgattct
    25561 tcattcaagc gcagtccaac tgccgtacac cgttctggat acttactcat agcatcacga
    25621 gaactggtat aggaagcagt gtgaggactg tgctgatgca tatagacctg atttttcaat
    25681 tcccactggt actgaggaaa atcctctctc agctttttct ccagtaataa ggtttcctca
    25741 taagaaaaat ctggatcaaa gaaaatcaca tctatatctg tttcatgatc aaaaggggat
    25801 ttgtctgaca aaagattcca gatgaaattt ctgacagaac ctgctgccaa ccacgagtct
    25861 ttcaaaccaa ggtctcggat gatcgtcaga atggccatca tatctggact ttctctaaaa
    25921 gcctctaaga tttcttgctt atttttcact gtattcataa cctaagtgct catatgcctt
    25981 agcagtcgcc acccgtccag accgtgtccg catgataaaa cctttttgaa tcaagtaagg
    26041 ctcatacata tcttcaactg tctcacgctc ttcggcgata ttcacagaaa gagttcctag
    26101 accaacaggt cctccactgt acatctcaat catggtacga aggatttttt gatccacata
    26161 gtccaaacct tcatggtcaa catccagcat agtcaaagcc ttatcggtaa taatatcatc
    26221 aattacccca ttccccatta tctgggcaaa atcgcgcacg cgcttgagga gacgattggc
    26281 aatacgaggg gtcccacgac tacgtagggc caactcagat gctgcctcat gagtgatttc
    26341 catctcaaaa atatctgccg tccgctcgac aatttctgtc aagtcagcat gggcataata
    26401 ctccatatgg cctgtaatcc caaaacgtgc ccgtagtgga tttgagagca taccagcccg
    26461 agtcgtcgca ccaatcaagg taaaaggtgg taactccaaa tgaacactac gactaccctc
    26521 accagcccca atcataatat ctatgtagaa gtcctccata gcactataaa gcacctcttc
    26581 cactgacatt ggcaaacgat ggatctcgtc aataaagagg acatctccag gctctaactc
    26641 attcaaaatc gctaccaaat cacccgcttt ttcgataaca ggaccagacg tttgcttgag
    26701 attgactccc agttcattgg caatgacaaa agccatggtt gttttcccaa gccctggagg
    26761 gccaaataag agcacatgat ccagtgcttc atcccgcatt ttagcggctt cgataaagat
    26821 ctgaagctga tccttaacct tatcctgacc aatatattca cgtaaatact gaggacggag
    26881 cgtgcgttct actaactcct catcacccat catctcatta tctaaaattc tactcatggc
    26941 tctattatat caaaaaaaca agccacaaac aaaaaagcca cctgattggg tgactcctaa
    27001 gtttagcact tatgtggtat aatattatac gacactgcta caccgcctac gaaaggaggt
    27061 gagatagccc atgatggaat tagtactcaa aactatcatc ggaccaattg tggtcggtgt
    27121 cgttcttcgt atagtcgata aatggctaaa caaggacaaa tagtgtcaaa aaagacctca
    27181 agcttatttg gtcgtgagct tggggtcttt tctagcctat gatatagaac tagtactcaa
    27241 ttccttttta ttatcacata gttcacgaat tttgtcaaag gtttacattt tcttcaaccg
    27301 ctgtacgaca agacggttaa gattaagaga acgttaggga ttctatcaat ttcatagaaa
    27361 ttttgatttc gtaaacgaag agacaatctt acatgtcact tctcatttaa tacgccacta
    27421 ctagacaagc aaaatcatta ttacagtagt tccagttctt caattaacag tcacttacaa
    27481 tcaaattgag tttgaactag ctgaagcgac cacagaccta tttcttagtc atattcgcta
    27541 aaaaagtccc cgccaattcc ccgaccaaaa tccgaaaaat accgaaaaat atcgaaaaat
    27601 ta
//
LOCUS       DAVLTT010000020        27336 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLTT010000020 DAVLTT010000000
VERSION     DAVLTT010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27336
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.020"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            30..557
                     /locus_tag="VYN15_001007"
     CDS             30..557
                     /locus_tag="VYN15_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV1452347.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            636..3329
                     /gene="pspC"
                     /locus_tag="VYN15_001008"
     CDS             636..3329
                     /gene="pspC"
                     /locus_tag="VYN15_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV1452348.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGIT
                     QVATSYNKANESQTEHRKAAKQVDEDIKKMLSEIQEYIKKMLSEIQLDKRKDTQNRTL
                     NRKLSAIQTKYLYELRVLKEKSKKEELTSKTKKELDAAFEKFKKEPELTKKLAEAKQK
                     AKAQKEEDFRNYPTNTYKTLELEIAEFDVKVKEAELELVKEEAKPRNEEKIKQAKEKV
                     ESKKAEATRLEEIKTERKKAEEEAKRKAEESEKKAAEAKQKVDTKEQGKPKRRAKRGV
                     SGELATPDKKENDAKSSDSSVGEETLPSPSLNMANESQTEHRKDVDEYIKKMLSEIQL
                     DRRKHTQNVNLNIKLSAIKTKYLYELSVLKENSKKEELTSKTKAELTAAFEQFKKDTL
                     KPEKKVAEAEKKVEEAKKKAKDQKEEDRRNYPTNTYKTLELEIAESDVKVKEAELELV
                     KEEANESRNEEKIKQAKEKVESKKAEATRLEKIKTDRKKAEEEAKRKAEESEKKAAEA
                     KQKVDAEEYALEAKIAELEYEVQRLEKELKEIDESDSEDYLKEGLRAPLQSKLDTKKA
                     KLSKLEELSDKIDELDAEIAKLEVQLKDAEGNNNVEAYFKEGLEKTTAEKKAELEKAE
                     ADLKKAVDEPETPAPAPQPAPAPEKPAEKPAPAPEKPVEKPAPAPEKPVEKPAPAPAP
                     EKPAPEKPAPTPETPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATG
                     WLQNNGSWYYLNSNGAMATGWLQYNGSWYYLNANGDMATGWFQYNGSWYYLNANGDMA
                     TGWLQYNGSWYYLNSNGAMVTGWLQNNGSWYYLNANGSMATDWVKDGDTWYYLEASGA
                     MKASQWFKVSDKWYYVNGSGALAVNTTVDSYRVNANGEWVN"
     gene            complement(3559..4539)
                     /gene="dusB"
                     /locus_tag="VYN15_001009"
     CDS             complement(3559..4539)
                     /gene="dusB"
                     /locus_tag="VYN15_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV1452349.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(4526..5398)
                     /gene="hslO"
                     /locus_tag="VYN15_001010"
     CDS             complement(4526..5398)
                     /gene="hslO"
                     /locus_tag="VYN15_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV1452350.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            5563..6990
                     /locus_tag="VYN15_001011"
     CDS             5563..6990
                     /locus_tag="VYN15_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1452351.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QPPVYYLKNDLDMEDLAGIRQLLFT"
     gene            7149..8657
                     /gene="glpK"
                     /locus_tag="VYN15_001012"
     CDS             7149..8657
                     /gene="glpK"
                     /locus_tag="VYN15_001012"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV1452352.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            8699..10525
                     /gene="glpO"
                     /locus_tag="VYN15_001013"
     CDS             8699..10525
                     /gene="glpO"
                     /locus_tag="VYN15_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV1452353.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQFGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            10595..11299
                     /locus_tag="VYN15_001014"
     CDS             10595..11299
                     /locus_tag="VYN15_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1452354.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            11490..11693
                     /locus_tag="VYN15_001015"
     CDS             11490..11693
                     /locus_tag="VYN15_001015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452355.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(11780..12388)
                     /locus_tag="VYN15_001016"
     CDS             complement(11780..12388)
                     /locus_tag="VYN15_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452356.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            13479..14756
                     /gene="ltrA"
                     /locus_tag="VYN15_001017"
     CDS             13479..14756
                     /gene="ltrA"
                     /locus_tag="VYN15_001017"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEV1452357.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKLKLKKLTQRKWSIALTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            15214..16392
                     /locus_tag="VYN15_001018"
     CDS             15214..16392
                     /locus_tag="VYN15_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1452358.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANLALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFN
                     "
     gene            16706..16837
                     /locus_tag="VYN15_001019"
     CDS             16706..16837
                     /locus_tag="VYN15_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV1452359.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            16858..18408
                     /gene="dltA"
                     /locus_tag="VYN15_001020"
     CDS             16858..18408
                     /gene="dltA"
                     /locus_tag="VYN15_001020"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV1452360.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMIMDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGVTHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQSLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            18405..19649
                     /gene="dltB"
                     /locus_tag="VYN15_001021"
     CDS             18405..19649
                     /gene="dltB"
                     /locus_tag="VYN15_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV1452361.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIATTLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGTIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALGISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            19663..19902
                     /gene="dltC"
                     /locus_tag="VYN15_001022"
     CDS             19663..19902
                     /gene="dltC"
                     /locus_tag="VYN15_001022"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV1452362.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            19895..21163
                     /gene="dltD"
                     /locus_tag="VYN15_001023"
     CDS             19895..21163
                     /gene="dltD"
                     /locus_tag="VYN15_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV1452363.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            21318..21758
                     /gene="adcR"
                     /locus_tag="VYN15_001024"
     CDS             21318..21758
                     /gene="adcR"
                     /locus_tag="VYN15_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV1452364.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            21758..22462
                     /locus_tag="VYN15_001025"
     CDS             21758..22462
                     /locus_tag="VYN15_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1452365.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            22455..23261
                     /locus_tag="VYN15_001026"
     CDS             22455..23261
                     /locus_tag="VYN15_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1452366.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            23271..24776
                     /gene="adcA"
                     /locus_tag="VYN15_001027"
     CDS             23271..24776
                     /gene="adcA"
                     /locus_tag="VYN15_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV1452367.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGKEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(25936..26709)
                     /locus_tag="VYN15_001028"
     CDS             complement(25936..26709)
                     /locus_tag="VYN15_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1452368.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSKLDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLPKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            26885..>27336
                     /locus_tag="VYN15_001029"
     CDS             26885..>27336
                     /locus_tag="VYN15_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HEV1452369.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTN"
BASE COUNT         8393 a         5072 c         5949 g         7922 t
ORIGIN      
        1 aaaatataga taaaagaaag gatactaata tggtattagc gattatttta gtaacattcc
       61 ttattcgatt gattttttta aagcgttcga tagagaatga gaaacgaatc cttagcaatg
      121 gcgggaaaga atttggagtt gagaatacaa aacgattaac gttggctcat attgtttttt
      181 atctctcttg cctcgttgaa gcaatggtgc ataagacaat gtttgatggt atgagcatgg
      241 ttggtttagt cttgcttatt ttttctatgc tgatgttgat gttggtgatt cacttgttgg
      301 gagatatttg gacagtgaag cttatgcttg tcaataatca caaatatgta gatcatatct
      361 tgtttaggac agtaaaacat cctaattact ttttaaatat tttacctgag ttgattggct
      421 tgaccttgtt gagtcatgcc tatatgactt ttgttttagt ttttccagtt tatgcagtta
      481 ttttgtatcg acgaatagct gaagaggaaa agctattaca tgaagttata atcccaaatg
      541 gaagcataaa gagataaata caaaattcga tttatataca gttcatattg aagtgatata
      601 gtaaggttaa agaaaaaata tagaaggaaa taaacatgtt tgcatcaaaa agcgaaagaa
      661 aagtacatta ttcaattcgt aaatttagta ttggagtagc tagtgtagta gttgctagtc
      721 ttgttatggg aagtgtggtt catgcgacgg agaatgaggg aattacccaa gtagccactt
      781 cttataataa ggcaaatgaa agtcagacag aacataggaa agctgctaaa caagtcgatg
      841 aagatataaa aaaaatgttg agtgagatcc aagaatatat aaaaaaaatg ttgagtgaga
      901 tccaattaga taaaagaaaa gatacccaaa atcgcacctt aaacagaaag ttgagcgcaa
      961 ttcaaacgaa gtatttgtat gaattaagag ttttaaaaga gaagtcgaaa aaagaagagt
     1021 tgacgtcaaa aacaaaaaaa gagttagacg cagcttttga gaagtttaaa aaagaaccag
     1081 aacttactaa aaaattagca gaagctaaac aaaaagccaa ggctcaaaaa gaagaagatt
     1141 tccgtaacta cccaaccaat acttacaaaa cgcttgaact tgaaattgct gagttcgatg
     1201 tgaaagttaa agaagcggag cttgaactag taaaagagga agctaaaccc cgaaacgagg
     1261 aaaaaattaa gcaagcaaaa gagaaagttg agagtaaaaa agctgaggct acaaggttag
     1321 aagaaatcaa gacagaacgt aaaaaagcag aagaagaagc taaacgaaaa gcagaagaat
     1381 ctgagaaaaa agctgctgaa gccaaacaaa aagtggatac taaagagcaa ggtaaaccaa
     1441 agaggcgggc aaaacgagga gtttctggag agctagcaac acctgataaa aaagaaaatg
     1501 atgcgaagtc ttcagattct agcgtaggtg aagaaactct tccaagccca tcccttaata
     1561 tggcaaatga aagtcagaca gaacatagga aagatgtcga tgaatatata aaaaaaatgt
     1621 tgagtgagat ccaattagat agaagaaaac atacccaaaa tgtcaactta aacataaagt
     1681 tgagcgcaat taaaacgaag tatttgtatg aattaagtgt tttaaaagag aactcgaaaa
     1741 aagaagagtt gacgtcaaaa accaaagcag agttaaccgc agcttttgag cagtttaaaa
     1801 aagatacatt gaaaccagaa aaaaaggtag cagaagctga gaagaaggtt gaagaagcta
     1861 agaaaaaagc caaggatcaa aaagaagaag atcgccgtaa ctacccaacc aatacttaca
     1921 aaacgcttga acttgaaatt gctgagtccg atgtgaaagt taaagaagcg gagcttgaac
     1981 tagtaaaaga ggaagctaac gaatctcgaa acgaggaaaa aattaagcaa gcaaaagaga
     2041 aagttgagag taaaaaagct gaggctacaa ggttagaaaa aatcaagaca gatcgtaaaa
     2101 aagcagaaga agaagctaaa cgaaaagcag aagaatctga gaaaaaagct gctgaagcca
     2161 aacaaaaagt ggatgctgaa gaatatgctc ttgaagctaa aatcgctgag ttggaatatg
     2221 aagttcagag actagaaaaa gagctcaaag agattgatga gtctgactca gaagattatc
     2281 ttaaagaagg cctccgtgct cctcttcaat ctaaattgga taccaaaaaa gctaaactat
     2341 caaaacttga agagttgagt gataagattg atgagttaga cgctgaaatt gcaaaacttg
     2401 aagttcaact taaagatgct gaaggaaaca ataatgtaga agcctacttt aaagaaggtt
     2461 tagagaaaac tactgctgag aaaaaagctg aattagaaaa agctgaagct gaccttaaga
     2521 aagcagttga tgagccagaa actccagctc cggctcctca accagctcca gctccagaaa
     2581 aaccagctga aaaaccagct ccagctccag aaaaaccagt tgaaaaacca gctccagctc
     2641 cagaaaaacc agttgaaaaa ccagctccag ctccagctcc agaaaaacca gctccagaaa
     2701 aaccagctcc aactccagaa actccaaaaa caggctggaa acaagaaaac ggtatgtggt
     2761 acttctacaa tactgatggt tcaatggcaa caggctggct ccaaaacaat ggctcatggt
     2821 actacctcaa cagcaatggc gctatggcga caggatggct ccaaaacaat ggctcatggt
     2881 actacctcaa cagcaatggc gctatggcga caggatggct ccaatacaat ggttcatggt
     2941 actacctcaa cgctaatggt gatatggcga caggatggtt ccaatacaat ggttcatggt
     3001 actacctcaa cgctaatggt gatatggcga caggatggct ccaatacaat ggttcatggt
     3061 actacctcaa cagcaatggt gctatggtaa caggatggct ccaaaacaat ggctcatggt
     3121 actacctaaa cgctaacggt tcaatggcaa cagattgggt gaaagatgga gatacctggt
     3181 actatcttga agcatcaggt gctatgaaag caagccaatg gttcaaagta tcagataaat
     3241 ggtactatgt caatggctca ggtgcccttg cagtcaacac aactgtagat agctatagag
     3301 tcaatgccaa tggtgaatgg gtaaactaaa cttaatataa ctagttaata ctgacttcct
     3361 gtaagaactc tttaaagtat tccctacaaa taccatatcc tttcagtaga taatataccc
     3421 ttgtaggaag tttagattaa aaaataactc tgtaatctct agccggattt atagcgctag
     3481 agactacgga gtttttttga tgaggaaaga atggcggcat tcaagagact ctttaagaga
     3541 gttacgggtt ttaaactatt aagccttctc caattgcaag agggcttcaa tctctgctag
     3601 ggtgctagct tgcgaaatgg ctccacggag tttggcagcg ccagatgttc cacggaggta
     3661 gtgaggagcg aggccgcgga attcacgaac tgcgacgttt tctcctttga ggttaatcaa
     3721 tcgtttcaag tgttcgtagg cgatcttcat cttgtcttca aaggtcaaat caggtaggat
     3781 ttctcctgtt tcaaagtaat ggttgatttg gttgaagagg taaggatttc ccatggcagc
     3841 tcggccaatc atgactgcgt cagcaccaac ttcttcgatg cgttgcttgg cttcttggac
     3901 agtacggata tcaccgttgg cgatgaatgg aatcttggtt agagcttggg caaccttgta
     3961 aagggtctca aggtctgcgt ggccagtata catttgttca cgggtacggc catgcatggc
     4021 gagggcagaa acacctgcag cttcagcagc gagggcattt tctactgcca gagatgggtc
     4081 cgcccagccg gtacgcattt tgacagtaag tgggatatca aggacagact ggaccttgtt
     4141 gatgatagag tagatcttgt caggatcctt gagccacata gcaccagctt cgttcttcac
     4201 gattttgttg acagggcagc ccatgttgat atcgacgata tcggtcttgg tgttttcttg
     4261 gatgaattct gctgcgcgtg ctaggctgtc ttcatcgcta ccaaaaagtt ggatagagac
     4321 agggttttcg ccctcatcga tatgaagcat gtgcagggtt ttttcgttgt tgtattggat
     4381 tcccttgtca gagaccattt ccattacaac gagtccagct ccgagctctt ttgcgatggt
     4441 acgaaaggct gagttggtca cgccagccat aggcgctaaa acggtacgat tgggaatctc
     4501 aacattgcca atcataaaag gtgtattaag atttgtcacg aatgagttcc tccaggtcct
     4561 tttcatcaaa gttgtaagta gtttggcaga attgacaagt gatttctgcc ccgtggtctt
     4621 cctctttcat ttcctgtaag tctgagcttg gaaggctggc aagagcgttc ataaagcgtt
     4681 catggctaca gtcacattgg aaacggattt cttcttcaga aagacgcttg taggcttcgt
     4741 ccccgtagat agccttgagg agggcttcga tatggtcgtc gctttcgaga agagtagaga
     4801 tagctggcat ttcttggatg cgtttttcaa agcgagcaat ctcttctttc ttggctcctg
     4861 gcaagacttg aactaggaaa ccacctgcaa ccttgacctt gtcttcctcg tccaaaagga
     4921 cattgaggcc gaccgctgaa ggcgtttgtt ggctttcagt aaggtaaaag gcaaggtctt
     4981 caccgatttc tccagagatg aggggagtta tagagttgta aggatttcca gcaccgtagt
     5041 ctgtgataac gaggaattga ccatttccaa caaaaggtcc gactaggact tcaccagtcg
     5101 cagtcttttt gatgtcaaca ccaggatttt gaacatagcc tttgacgttc cccttggtat
     5161 cagcgacggt gataatagca cctagagagc tagagcccaa caccttaact gtaagtttgg
     5221 tatttccttt ttcattggct gcgagaatct ggctggcgat aagagttcga ccaagcgcta
     5281 cagttgagct agcttgggtt tgatgttttt cttgagcagt gcggacggtt tccgtgctat
     5341 caaggacaaa agcacgaaag gctccgcttt ctgatatagt tttaataatt ttatccatag
     5401 ctactatttt agcataaaaa tgcccaaagg gggagccgtg tgtttactga ttttcaggat
     5461 aatggaccag gaaatcagca tgaaaataaa aagagaaaca gattatttta gcatttgtaa
     5521 gatttatgct atgcttaagg tagaaaatga aaggggtaac aaatgtattt aggagatttg
     5581 atggagaaag ccgagtgtgg tcaattttca atcctttcct ttctattaca agagtctcag
     5641 acgaccgtca aggctgtaat ggaagaaaca ggattttcaa aagcaaccct aaccaaatat
     5701 gtcaccctgc tcaatgacaa ggctttggat agtggcttag agctggctat tcactcagaa
     5761 gatgaaaatc tgcgtctgtc tatcggtgca gctaccaagg ggagagatat tcggagcttg
     5821 tttttggaga gtgctgttaa ataccagatt ttggtttatc ttctctacca ccaacagttt
     5881 ttagcccatc agctggctca agaattggtg attagcgagg ctacgcttgg tcgtcacttg
     5941 gctggtttaa atcagatttt gtcagaattt gatttatcca tccaaaatgg acgttggcga
     6001 ggtccagagc atcagattcg ctatttctat ttctgtcttt tccgaaaggt ctggtcgagt
     6061 caggaatggg aaggtcacat gcagaaacca gagagaaaac aggagattgc caatttagag
     6121 gaaatctgcg gtgcaagttt gtctgtgggg cagaaattgg acttggttct ctgggctcac
     6181 atcagtcaac aacgtcttcg ggtcaatgct tgtcagtttc aagtcataga agagaaaatg
     6241 cgagggtatt ttgacaatat tttctacctt cgtttgctga gaaaggttcc gtcctttttt
     6301 gctgggcaac atattccact aggagttgag gatggtgaga tgatgatatt cttctctttt
     6361 ctcctatctc atcgcattct tcctcttcat actatggagt atattcttgg ttttggaggg
     6421 cagttggcag atttactgac gcaattgatt caagaaatga agaaggagga actattgggg
     6481 gattatacag aggaccatgt cacctatgaa ctcagtcagc tttgtgctca agtctatctc
     6541 tataagggct atattttaca ggatcgctac aagtaccagt tagagaatcg tcatccatat
     6601 ttactgatgg aacatgattt taaagagaca gcagaggaga tttttcatgc tctacctact
     6661 tttcaacagg ggacagattt agataagaag attctctggg aatggctcca gttaatcgaa
     6721 tatatggctg aaaacggtgg ccagcatatg cggattggtc tggatttgac atctggtttt
     6781 cttgtctttt caaggatggc agccattttg aaacggtatt tggaatacaa tcgttttatt
     6841 accattgaag cttatgaccc tagtcggcat tatgatttgc tggttaccaa taacccgatt
     6901 cataagaagg aacagccccc agtttattat ttaaaaaatg acttggatat ggaagatttg
     6961 gcagggattc gtcagttatt attcacttaa aaggcttggt taatccaggt cttttttgtg
     7021 aaattcacac aatctcctca cattttttta aaaattaaaa aaagttgata aacaagaaag
     7081 cgctttattt tgtatactag taagtgtaaa gaggaaacac ctcaagatct ttatcaggag
     7141 gacagtatat gtcacaagaa aaatacatca tggccattga ccagggaact acaagttctc
     7201 gtgccatcat tttcaacaaa aaaggggaaa aggttagctc gagtcaaaaa gagtttaccc
     7261 agattttccc tcaggcaggt tgggttgagc acaatgccaa tgaaatttgg aactctgttc
     7321 agtcagttat tgcgggtgct ttcatcgaaa gtggtgtcaa gccaaatcaa atcgaggcaa
     7381 tcgggattac caaccaacgt gaaacaacgg ttgtctggga taagaaaaca ggacttccta
     7441 tctacaatgc tatcgtttgg cagtcacgcc agacagcacc tttggctgag caactaaaaa
     7501 gccaaggtta tgtggaaaaa ttccatgaaa agactggttt gattattgat gcttacttct
     7561 ctgctaccaa ggttcgttgg attttggatc atgtagaagg cgctcaagag cgagcagaaa
     7621 aaggggaatt gctctttggt actatcgata cttggttggt ttggaaattg actgacggtg
     7681 cggctcacgt gactgactac tcaaatgcag ctcgtaccat gctttataac attaaagaac
     7741 tcaaatggga tgatgaaatt ttggaaatcc ttaacattcc gaaggctata cttccagaag
     7801 ttcgttctaa ctccgaaatc tacggcaaga cagctccatt ccatttctac ggtggagagg
     7861 tgccaatctc aggtatggct ggggaccaac aagcagccct ctttggacag ttggcttttg
     7921 agccaggtat ggttaagaat acttatggaa caggctcttt catcatcatg aatactgggg
     7981 aagagatgca gttgtctgaa aacaacctct tgacaaccat tggttacgga atcaacggta
     8041 aggtttatta tgccttggaa ggttctatct tcatcgcagg aagtgctatt cagtggcttc
     8101 gtgacggtct tcgcatggtt gaaaattcac cagaatctga aaaatacgct cgtgattctc
     8161 acaacaacga tgaagtttat gtcgttccag cctttacagg tctaggcgct ccatactgga
     8221 accaaaatgc tcgtggttcc gtctttggtt tgactcgtgg aacaagcaaa gaagacttta
     8281 tcaaggcgac tttgcaatct attgcttatc aagtgcgtga catcatcgac accatgcaag
     8341 tggatactca gaccgccatt caagtactga aggtggatgg tggtgcagcc atgaacaact
     8401 tcctcatgca attccaggcg gatattttag gcattgacat tgcacgtgct aaaaacttgg
     8461 aaacaacagc tctaggagcg gccttcctag caggtttgtc agtagggtac tggaaagact
     8521 tggacgagtt gaaactcttg aacgagacag gagaactctt tgagccatct atgaatgaat
     8581 ctcgcaagga acaactctac aagggctgga agaaggctgt gaaagcaact caagtctttg
     8641 cggaagtaga cgactaatac tggcagaata aagcgattta tttagaaagt gtgtaaatat
     8701 ggaattttca aagaaaacac gtgaattgtc aattaaaaaa atgcaggaac gcaccctgga
     8761 cctcttgatt atcggtggag gaatcacagg agctggtgta gccttgcagg cggcagctag
     8821 cggtcttgag actggtttga ttgaaatgca agactttgca gaaggaacat ctagtcgttc
     8881 aacaaaattg gttcacggag gacttcgtta cctcaaacaa tttgacgtag aggtggtctc
     8941 agatacggtt tctgaacgtg cagtggttca acaaatcgct ccacacattc caaaaccaga
     9001 tccaatgctc ttaccagttt acgatgaaga tggagcaacc tttagcctct tccgtcttaa
     9061 agtagccatg gacttgtacg accttttagc aggtgtgagc aacacaccaa ctgcgaacaa
     9121 ggttttgagc aaggatcaag tcttggaacg ccagccaaac ttgaagaagg aaggcttggt
     9181 aggaggtgga gtgtatcttg acttccgtaa caacgatgcg cgtctcgtga ttgaaaacat
     9241 caaacgtgcc aaccaagacg gtgccctcat tgccaaccac gtgaaggcag aaggcttcct
     9301 ctttgacgaa agtggcaaga ttacaggtgt tgtagctcgt gatctcttga cagaccaagt
     9361 atttgaaatc aaggcccgtc tggttattaa tacaacaggt ccttggagtg ataaagtacg
     9421 taatttgtct aataagggaa cgcaattctc acaaatgcgc ccaactaagg gagttcactt
     9481 ggtagtggat tcaagcaaaa tcaaggtttc acagccagtt tactttgaca caggtttggg
     9541 tgacggtcgt atggtctttg ttctcccacg tgaaaacaag acttactttg gtacaactga
     9601 tacagactac acaggtgatt tggagcatcc aaaagtaact caagaagatg tagattatct
     9661 acttggcatt gtcaacaacc gctttccaga atccaacatc accattgatg atatcgaaag
     9721 cagctgggca ggtcttcgtc cattgattgc agggaacagt gcctctgact ataatggtgg
     9781 aaataacggt accatcagtg atgaaagctt tgacaacttg attgcgactg ttgaatctta
     9841 tctctccaaa gaaaaaacac gtgaagatgt tgagtctgct gtcagcaagc ttgaaagtag
     9901 cacatctgag aaatatttgg atccatctgc agtttctcgt gggtctagct tggaccgtga
     9961 tgacaatggt cttttgactc ttgctggcgg taaaatcaca gactaccgta agatggctga
    10021 aggagctatg gagcgcgtgg ttgacatcct caaagcagaa tttgaccgta gctttaaatt
    10081 gatcaattct aaaacttacc ctgtttcagg tggagaattg aacccagcaa atgtggattc
    10141 agaaatcgaa gcctttgcgc aatttggagt atcacgtggt ttggatagca aggaagctca
    10201 ttacctagca aatctttacg gttcaaatgc accgaaggtc tttgcacttg ctcacagctt
    10261 ggaacaagcg ccaggtctta gcttggcaga caccttgtcc cttcactatg caatgcgcaa
    10321 tgagttgact cttagcccag ttgacttcct tcttcgtcgt accaatcaca tgctctttat
    10381 gcgtgatagc ttggatagta tcgttgagcc aattttggat gaaatgggac gattctatga
    10441 ctggacagaa gaagaaaaag caacttaccg tgctgatgtc gaagcagctc tcgctaacaa
    10501 cgatttagca gaattaaaaa attaagaaaa aataaaagag gtggagggca gcattccttg
    10561 tcgcccgtcc cttcttttta atggagacag aaagatgatg aatgaattat ttggagaatt
    10621 tctagggact ttaatcctga ttcttctagg aaatggtgtt gttgcaggtg tggttcttcc
    10681 taaaaccaag agcaatagct caggttggat tgtgattact atgggttggg ggattgcagt
    10741 tgcggttgca gtctttgtat ctggcaagct cagtccagct catttaaacc cagctgtgac
    10801 catcggtgtg gccttaaaag gtggtttgcc ttgggcttcc gttttgcctt atatcttagc
    10861 ccagttcgca ggggccatgc tgggtcagat tttggtttgg ttgcaattca aacctcacta
    10921 tgaggcagaa gaaaatgcag gcaatatcct ggcaaccttc agtactggac cagccatcaa
    10981 ggatactgta tcaaacttga ttagcgaaat ccttggaacc tttgttttgg tgttgacaat
    11041 ctttgctttg ggtctttacg attttcaggc aggtatcgga acctttgcag tgggaacttt
    11101 gattgtcggt atcggtctat cactaggtgg gacaacaggt tatgccttga acccagctcg
    11161 tgaccttgga cctcgtatca tgcacagcat cttgccaatt ccaaacaagg gagacggaga
    11221 ctggtcttac gcttggattc ctgttgtagg ccctgttatc ggagcagcct tggccgtgct
    11281 tgtattctca cttttctaat ctagaaaaca attatgttga tagagcttgg gcaagagccc
    11341 aatttcagca aaaaatgaag taaatcttct cataataaaa cgcatcatat caagcacgaa
    11401 aattccacga ggtcaactac agtcagaaag ctgaacaaca agccaaaacg cccaaaaaag
    11461 gcggcaaaaa gcaagcacct gcaagcaacg tgccgaaatg gtcaaatcct gattatgtca
    11521 acgaattaga cccaaaaatc gttgatatgc tagtagaatt tcacaagtca caaggcactt
    11581 tggaaactcc cgaggcgcaa gcagaaatcg cccaaaaacg tgaagaaatc gagcaaagga
    11641 gagctgagct tgaggataaa aaacaagagc ttttgaaccg cttgaacaaa tagagtttcg
    11701 caagtattat gcttacaaat tacttgagca attaactaaa atataaaccc tgcctttata
    11761 tctaggcagg gtttatattt tagaaattca cgtaggttgt tacggttttt acatacccag
    11821 tatagtttga gtttctatag tattcagtga taaacttcca ttttctttga gcaacatgga
    11881 tataagtact tgttatgtag tatggatatg ggctttgtga atccaagtaa gactgataag
    11941 cttgtatacc aaaatatgct ccaccaatta ttgcacccca tggacccccc aataaagcac
    12001 ctatcctacc aatcatataa ctgattccag caccagtcat gaagttagcg aatgtgttag
    12061 cttgtttatt cccatgtatt gtgttgacgt aattccaaac attaggatcg tatgatctaa
    12121 aagatatatt taggtcgatt tcattctttt gataagccat ataaaatgcc ccattgatat
    12181 agacgccgtc agcacgtcgt tcaatagtgt ctacacttcc atctggattg acaacctcaa
    12241 gaacttcatc gcttaaaata tttacttgcg tatctccgaa ccgcactgat gagccattct
    12301 caaactgagc ctcaccagat acaactttag agtttgccga taagctatca tcagcaaaaa
    12361 caacaagcga cggggaaatg ctagacatac agaaaacaga cataactagc aaacacatgc
    12421 atttaaacat cttagacata acggaaactc ctttgtattt ttgatttttt ttaactttta
    12481 ttatacaata aaaccaaata aaaagaaagc ggtaacaata tgcttaatgc gaaaattttt
    12541 tatatatttt tatgtttgat cgttatcgaa actacaggct tgttgttgtt gaaaagaggt
    12601 ctcgaaatgg gttatttaga cacagaagct attatcctcg cagttttttc atttgctttt
    12661 tacaacctat gttcattcgc ttgggtctgc tctacaataa aaaacaataa aaaataaata
    12721 gacgtatttt caaaaaaaaa aaaaaatgca tatttatctt agcaaaacga cgatttaaat
    12781 cgtcgttttt ttgtagtacg acgggcatgt cgtatatctg aggtgtaagt cctcggtggg
    12841 cacctgctac cggtgaaccc aatagcgatt cccaagcctg actatcgtga ggtagcaggg
    12901 agaggaaggg atagcgaaat cgtggctcta cgaacaggaa cgtgatagta aggcgtatat
    12961 agcggataag gaggcttcaa actctaaagt ccaaaaaggt agtcgtaacc tatatgtgta
    13021 aatcacgaga gtaattgaat tcggactaag gtttgtgtga aaaagataaa tctttctaga
    13081 gtctaaagac tctgcgtcag atttcctatt ttcactgtaa ccttttaacg tcctcatatc
    13141 ttgtataaac gaggaaagat gtacgactta tcccgtgagg tttcatgagc gctgaaagcg
    13201 tagtaacaac gaatcatgag aagtcagccg agcccatagt agtgaggaaa tttccgtaat
    13261 ggaagtggag cgaaggggtg aatactcaaa cagtctgggg agagactgtt tgaggtctgt
    13321 cgctagaaag agaaaacgac agatcgaagt aatcctactt cacttgtgtc tgtaaaatga
    13381 gtggtctgat agaactggac tttgacacgt aatgactaga tgaaggttca ccaatataag
    13441 atgtccctca ggcaccaaaa caagaaagga atacgcacat gtcaaaactg ctagataaga
    13501 tattatcacg cgaaaatatg ctggaagcct acaatcaagt aaaatccaat aaaggctcag
    13561 ctgggattga tggaatgact atcgaagaga tggataatta tctcagacaa aactggcgct
    13621 tgactaagga actgataaaa cagagaaaat ataagcctca accagttctt aaagttgaga
    13681 tacctaaacc agacggaggc atccgtcaac taggaattcc aacagttatg gatagaatga
    13741 ttcaacaggc cattgtccaa gttattagcc ccatttgtga accccatttc tcagatacga
    13801 gttatggctt cagaccaaat aggtcatgtg aaaaagccat catgaagctc ttagaatact
    13861 taaatgacgg ctatgagtgg atagtggata tagacctaga gaaatttttc gatacagttc
    13921 ctcaagatag attgatgtcc ttagtacata acattatcga agacggagat acggaatcct
    13981 tgattcgtaa gtatcttcat tcaggtgtta tcattaatgg tcaacgttat aaaacactag
    14041 ttggtacacc acagggagga aatttatctc ctctcttatc caatatcatg cttaatgaat
    14101 tggacaagga attagaaaag aggggacttc gatttgtgcg ctacgcagat gattgtgtga
    14161 ttacggtcgg aagcgaggca gccgctaagc gtgtgatgta ttcagtcagt cgttttattg
    14221 agaaacggct aggtttgaaa gtaaacatga ccaagactaa gattaccaga ccaagagagt
    14281 tgaaatatct aggttttggg ttctggaaat catcagatgg ttggaaaagc cgtccacatc
    14341 aagatagtgt tcggagattt aagcttaaat tgaagaaact aacacagagg aaatggagta
    14401 tagctctaac aagacgtatt gagcaactga atttgtctat tcgaggatgg ataaactatt
    14461 tctcattggg aaatatgaaa agtatagtcg ccagcataga tgagcgcttg cgtactcgcc
    14521 tacgagtgat tatctggaag caatggaaga agaaatcgag acgattatgg ggattgctta
    14581 agttaggagt tcctaaatgg atagcagata aggtatctgg ctggggcgac cattatcaat
    14641 tagtagctca gaagtcggta cttaaacgtg ctatatcaaa accagtcctt gaaaaacgtg
    14701 gactggtttc gtgtttggat tattaccttg aacgacatgc gttaaaagtt agttgaaccg
    14761 ccgtatgccg aacggcacgt acggtggtgt gagaggggct agagattatc ccctactcga
    14821 ttaactcccc tgaaatttat tttaattatg caaatttcac gtatttttga tgctgagacg
    14881 acgatcctgg gaacttttca gatatttttt tgactatcta aaatctatca ttagaaaagc
    14941 ttagagcgcc aaaggatttg agcgtttttc tgatttttaa gactttttcc cagtctcttt
    15001 ttcgattgaa gatgtaatta ttctactaac taactaactt cttagtacta gccaacaacg
    15061 ataatcataa ttcctcctaa aattaggaat aataaaggca atagtttttg ttttttcatg
    15121 taaaaaacct cacttttgtt ttctgctatt ttatgctaaa atattaaaaa tcaaatttaa
    15181 ttccaaagtt tgtaactaaa gggggagcgc tacatgtcta attcatttgt caagttgtta
    15241 gtctctcaat tatttgcaaa tttagcagat attttcttta gagtaacaat cattgctaac
    15301 atatacatta tttcaaaatc agtaattgcc acatcactag ttcctatctt aataggaata
    15361 tcctcttttg ttgcgagtct tttagttccg ttggttacta aaaggttagc gctaaatagg
    15421 gttttatctt tatctcaatt tggaaagact atattattgg cgatactggt aggaatgttt
    15481 accgtaatgc aatccgtagc gcctttggtg acctatctat ttgttgttgc aatttccata
    15541 ctagatggtt ttgcagcacc cgtttcctat gctattgtgc cacgctatgc gaccgatttg
    15601 ggtaaggcta atttagcctt atcaatgact ggtgaagctg ttcaattgat aggttgggga
    15661 ttaggtggac tcttgtttgc aacaattggt ctgttaccta ccacgtttat cattttagtc
    15721 ttgtatatca tttctagctt tctgatgtta tttcttccta acgctgaagt ggaggtgtta
    15781 gagtcagaaa ctaatcttga aattttgctc aaaggttgga agttagttgc tagaaatcct
    15841 agattaagac tttttgtatc agcaaattta ttggaaattt tttcaaatac gatttgggtt
    15901 tcttccatta tacttgtttt tgtaacggag ttattaaata aaacggaaag ttactgggga
    15961 tattctaata cagcatactc tattggtatt ataattagtg gcttaattgc ttttaggcta
    16021 tctgaaaagt tccttgctgc taaatgggaa agtattcttt ttcctcttgt agctatggca
    16081 atagtgacac tgactattct atattttcca aacgcacaga tgtttttatt attttcagct
    16141 ttagttggta tgttatcgca actaaaagaa gttcctgaaa gtgtatttct tcaggaaaca
    16201 gtagaggaaa atcatttagt taatgtctat tccgttcttg aagtgatttc tacattagca
    16261 ttttcagtat ttgttttgct aatgagctat attactgaga gttttggtat tagcatcagt
    16321 ttttggctat cagccatttg tctgatgata gaagctattt taatttatat cagacgagat
    16381 tattttaact gagagagtgg ttaaaaagtc tttaaaaatc agaaaagcgc atagtatcag
    16441 gtgttgaaaa aacttgatat tgtgtgtttt attatgggaa gatttacttc attgtctcct
    16501 gaaatggagt tttgaagcag gatcactcta tttgaaaata tacatagaaa aaccgcataa
    16561 tccttaaaat aagctgaaat ctattggaaa catacggtaa acaattgaaa agatactata
    16621 taaagtggta caatggtaga aaaataagct agtaagaatc actcttattt tagcgaaaaa
    16681 ttacagaaat gaatggtttt tcttgatgaa acagagaaaa gaattgtacc tctttcttgg
    16741 tcggacagcc ttgtattttc ttatctttct agggctgctt tacttcttta gctatcttgg
    16801 tcagggtcaa ggaagcttta tctataatga attttaactt gaaggagaat ccctattgtg
    16861 tcaaataaac caatagcaga tatgattgaa accattgagc attttgctca gacacagcct
    16921 agctatcctg tctataatgt tttggggcag gaacacactt atggcgattt aaaggctgat
    16981 tcggatagtt tggctgcagt cattgaccaa ctaggcttgc ctgagaagtc tcctgtggtt
    17041 gtttttggtg gccaagaata tgaaatgttg gcaacctttg tagcgctgac taagtcaggt
    17101 catgcctaca ttccaattga tagccattcg gccttggagc gagtttcagc tattttagaa
    17161 gtagcagagc caagcttgat tattgccatt tcagcctttc ccttggagca ggtttctaca
    17221 ccaatgataa atctagctca ggttcaagaa gcctttgccc aagggaacaa ctatgaaatc
    17281 acgcatccag tcaagggaga tgataattac tacattatct ttacttctgg tacgactggt
    17341 aagcctaagg gagtgcagat ttcacatgat aatctcctca gctttacaaa ctggatgatt
    17401 atggataagg aatttgcgac accgagtcgt ccgcaaatgc tggcacagcc accttattct
    17461 tttgacttgt ctgtcatgta ttgggcaccg accttggcac ttggtggtac gcttttcact
    17521 cttccttcag tcatcactca ggactttaag caactctttg cggctatctt ttcattgcca
    17581 atcgctatct ggacatcaac accatccttt gcagatatgg ccatgttgtc tgaatacttc
    17641 aacagtgaga aaatgcctgg agtcacgcat ttctactttg atggtgaaga attgacggtc
    17701 aaaacagctc aaaaactgcg cgagcgtttc ccaaatgccc gtatcatcaa tgcttacggc
    17761 ccaacagaag cgacagtagc tctgtcagca gttgccgtga cagacgagat gttagcgact
    17821 ctcaaacgcc taccaatcgg ctataccaag gctgattctc caacctttat cattgacgag
    17881 gaaggaaata aactgccaaa tggcgaacag ggagaaatca ttgtttctgg gccagctgtt
    17941 tcaaaaggtt atatgaacaa tcctgaaaaa acagcagaag ccttctttga gtttgaaggt
    18001 ctgccagcct atcacacagg cgatgtggga accatgacag atgagggctt gcttctctac
    18061 ggcggacgca tggacttcca gattaagttt aacggttacc gcattgagtt agaagatgtc
    18121 tctcaaagcc tcaacaagtc tcgctttatc gaatctgctg tcgcagtacc gcgctataac
    18181 aaggaccaca aggtacaaaa tctattggct tatgtcatct taaaagacgg tgttcgtgag
    18241 cagtttgagc gagatatcga tattaccaag gccatcaagg aagacctgac agacatcatg
    18301 atgtcctaca tgatgccatc taaattcctt taccgagaca gtttgccact aactccaaat
    18361 ggaaagattg acatcaaagg attgattaac gaggtgaata agagatgatg gagttttttc
    18421 aacagcttcc tcatttagag ccatatggca atcctcagta ttttgtttat gtgattgcta
    18481 caaccttgcc catctttata ggcctctttt tcaagaaacg ctttgcctgg tatgaagtgt
    18541 tggtaagtct cttctttatt gtcaccatgt tggtgggtgg aaagaccaat caactagctg
    18601 ccttgggtat ttacctttgc tgggaaatat tgctcctgct tttctacaag cattatcgaa
    18661 aaagcaagga tggcaagtgg gtcttctact tagttagttt tctgtcccta cttccgatta
    18721 tctttgtcaa ggtgcaacca gctatcaatg gaacgcagtc tttgcttggg ttcttgggaa
    18781 tttcttacct gacctttcgt tcggttggga ctatcatcga gctgagagat ggagtgatta
    18841 aggattttac cctctgggaa ttcctccgtt tccttctctt catgccaact ttctcgagtg
    18901 gtccaatcga tcgctttaag cgatttaatg aaaattatca ggccattcct gagcgagatg
    18961 agttgatgga tatgctggat gaatctgtcc gctatatcat gtggggcttt ttgtataagt
    19021 ttattctagc tcatgtttta ggagagacct tactacctcc tctgaagaat ttagccttgc
    19081 agtcaggtgg cttctttaat ctctatgcct tggcagttat gtatactttt ggtctggagc
    19141 tcttctttga ttttgcaggt tattctatgt ttgctttggg catctcaaac ttgatgggaa
    19201 tccgtagccc tatcaacttt aacaagccct ttttatcaag ggatttaaag gagttttgga
    19261 atcgctggca tatgagtctg tccttctggt tccgtgactt tgtctttatg cgaatggtga
    19321 tggtgttaac cagaaagaaa gtctttaaaa atcgtaatgt aacctcaagc atggcctaca
    19381 ttgtaaatat gctgattatg ggattttggc atggtgtgac ctggtactat atcgcctatg
    19441 gactctttca tggactaggc ttggtcatca atgatgcctg ggttcgcaag aaaaaaacgc
    19501 tcaataagga acggaaaaaa gcagggaagg ctgccctacc tgagaatcgc tggattcagt
    19561 tgcttggcat ggttgtcact ttccatgttg tcatgttgtc attcttaatc ttttctggat
    19621 tcttgaataa tctatggttt aaaaaataaa aggaaataaa atatggatat caaatcagaa
    19681 gttattgaaa ttattgatga gttgtttatg gaagatgttt ctgacatgat ggatgaagat
    19741 ctttttgatg caggtgtctt ggatagtatg ggaacggttg agttgattgt ggagattgag
    19801 aaccgttttg acattcgtgt ccctgtaaca gagtttggtc gtgacgactg gaatacagct
    19861 aataaaatca tagctggtat tgtggagcta caaaatgctt aaacgcttat ggatgatctt
    19921 cggaccggtc ttgatcgctg gtttgttggt ttttctgctc attttctttt atcctactga
    19981 gatgcatcat aatctaggag ctgaaaagcg ttcagcagtg gctactacta tcgatagttt
    20041 taaggagcga agtcaaaaag tcagagcact atctgatcca aatgtgcgtt ttgttccctt
    20101 ctttggctct agtgaatggc ttcgttttga cggtgctcat cctgcggtat tagctgagaa
    20161 atacaatcgt tcctaccgtc cttatctttt aggacagggg ggagctgcat cgcttaacca
    20221 atattttgga atgcaacaga tgttaccaca gctggagaat aaacaagttg tgtatgttat
    20281 ctcacctcag tggttcagta aaaatggcta tgatccagca gccttccagc agtattttaa
    20341 tggagaccag ttgactagtt ttctgaaaca tcaatctggg gatcaggcta gtcaatatgc
    20401 agcgactcgc ttactgcaac agttcccaaa cgtagctatg aaggacctgg ttcagaagtt
    20461 ggcaagtaaa gaagaattgt cgacagcaga caatgaaatg attgaattat tggctcgttt
    20521 taatgaacgc caagcctcct tttttggtca gttttcggtt agaggctatg ttaactacga
    20581 taagcatgta gctaagtatt taaaaatctt gccagaccag ttttcttatc aagcaataga
    20641 agatgttgtc aaagcagatg ctgaaaaaaa tacttccaat aatgagatgg gaatggaaaa
    20701 ttatttctat aatgagcaga tcaagaagga tttgaagaaa ttaaaggatt ctcagaaaag
    20761 ctttacctat ctcaagtcgc cagagtataa tgacttgcag ttggttttaa cacagttttc
    20821 taaatctaag gtaaacccga tttttatcat tccacctgtt aataaaaaat ggatggacta
    20881 tgctggtcta cgagaggata tgtaccaaca aacggtgcag aagattcgct accagttaga
    20941 aagtcaaggt tttaccaata tagcagattt ttctaaggac ggcggggagc ctttctttat
    21001 gaaggacacc attcaccttg gttggttggg ttggttggct tttgacaagg cagttgatcc
    21061 tttcctatcc aatcccacac cagctccgac ttaccatctg aatgagcgct ttttcagcaa
    21121 agattgggcg acttatgatg gagatgtcaa agaatttcaa tagataatat aatatagaag
    21181 agttcaagaa tgaaactagt tttcacgttt tttcttgact ctttttttgc ttgtgatata
    21241 attaactggt aaacaaaatg tcaaagaata gtatttttct cttaaaaaag agaagtctaa
    21301 aaggaaagga gtcagatatg agacagctag caaaggatat caatgctttt ttgaatgagg
    21361 tgattttgca ggcggaaaat cagcatgaaa tcctaatagg tcattgcact agcgaggtgg
    21421 ccctgaccaa tactcaggag catatcctta tgctcttgtc agaggaatct ttaacaaatt
    21481 cagaattggc ccgtcgtctc aatgtcagtc aggcggcagt taccaaggcc attaagtctt
    21541 tggtcaagga agggatgttg gaaacatcta aagattctaa agatgcgcgt gtgatttttt
    21601 atcagttgac tgacttggct cgtccaatcg ctgaggagca ccaccatcac catgagcata
    21661 cacttttaac ctatgaacaa gtggcgactc agtttactcc aaatgaacaa aaagtgattc
    21721 agcggttttt gactgcttta gtaggagaaa tcaaataatg agatatatta cggtagagga
    21781 tttgtccttc tattatgata aggagcctgt tcttgaacat atcaattatt gtgttgatag
    21841 tggggaattt gttaccttga ctggggaaaa tggagcggct aagacgacgc tcatcaaggc
    21901 tagtcttgga attctgcaac cacgcattgg aaaggtggct atttcaaaga caaatacgca
    21961 aggtaagaaa ttgagaatag cctatcttcc tcaacaaatt gccagtttta atgctggttt
    22021 tccaagtacg gtctatgaat ttgtcaagtc gggtcgctat ccgagaaaag gctggttccg
    22081 tcgtttgaat gctcatgatg aggagcatat caaggctagt ctggactcag ttggcatgtg
    22141 ggaacatcga gacaaacgct tggggtctct atctggggga caaaagcagc gagcggtaat
    22201 tgcgcgtatg tttgcttctg accctgatgt gtttatccta gacgagccga caacggggat
    22261 ggatgcagga agtaaaaatg aattttacga actcatgcac cacagcgccc atcatcatgg
    22321 caaggctgtt ttgatgatta cccatgaccc tgaagaagtt aaggattatg cggatcgcaa
    22381 tattcatcta gtccgtaacc aagactcgcc atggcgttgt ttcaatgttc atgagaatgg
    22441 ccaggaggtg ggccatgctt agtttattat cttacgactt tatacagcgc gcctttttgg
    22501 cggttattgc tatgagtctt ttctcaccgg tattgggaac cttcctcatc ttgcgtcgtc
    22561 agagtttgat gagtgatacc cttagccacg tctcactttc aggtgtagcc tttggtctgg
    22621 ttttggggat ttctccaact gtttctacta ttgccattgt cttgattgcg gcggtctttc
    22681 tggagtatct ccgtacggtt tacaagagct ttatggaaat cgggacagct atcctcatgt
    22741 caacaggtct ggctgtttct ctgattgtca tgagcaaggg taaaagctcg agttcaatga
    22801 gtttggacca atatctcttt ggttcgatcg tgactatcag tgaagaacag gtcatttccc
    22861 tctttgtcat tgcggcggtt gttttgattt tgacctttct ctttcttcgt cctatgtata
    22921 tcttaacttt tgacgaagat acggcctttg tggatggctt gccagttcgt accatgtcca
    22981 ttctttttaa catggtgaca ggggtggcta ttgcccttat gattcctgca gcaggagctc
    23041 ttctggtatc gaccattatg gtcttgccag ctagtattgc cctgcgtctg gggaaaaact
    23101 ttaaatcggt tatgctgctt gccagtgcga ttggcttttt gggaatggta gcaggacttt
    23161 acatttccta ctatgcagaa acacctgcaa gtgcaagtat taccattatt tttgtaactg
    23221 tctttatact aatcagttta gtaagacgtt ttatcaaata ggagacgaac gtgaaaaaaa
    23281 ttagcttatt actagccagt ctatgtgcct tgtttttagt ggcttgttcc aatcaaaaac
    23341 aggcagatgg taaactcaat atcgtgacaa ccttttaccc tgtctatgaa tttaccaagc
    23401 aagtcgcagg agatacggct aatgtagaac tcctaatcgg tgctgggaca gaacctcatg
    23461 aatacgaacc atctgccaag gcagttgcca aaatccaaga tgcagatacc ttcgtttatg
    23521 aaaatgaaaa catggaaaca tgggtaccta aattgctaga taccttggat aagaaaaaag
    23581 tgaaaaccat caaggcgaca ggcgatatgt tgctcttgcc aggtggcaag gaagaagagg
    23641 gagaccatga ccatggagaa gaaggtcatc accatgagtt tgacccccat gtttggttat
    23701 caccagttcg tgccattaaa ctagtagagc acatccgcga cagcttgtca gcagattatc
    23761 ctgataaaaa agagaccttt gagaagaatg cagctgccta tatcgaaaaa ttgcaagcct
    23821 tggataaggc ttacgcagaa ggcttgtctc aagcaaaaca aaagagcttt gtgactcaac
    23881 acgcagcctt taactatctt gccttggact atggactcaa acaagtcgca atctcaggac
    23941 tttctccaga tgcagagcca tcagctgctc gcttggcaga attgacagag tatgtcaaga
    24001 aaaataaaat cgcctatatc tattttgaag aaaatgcctc acaagccctt gctaacacac
    24061 tttcaaaaga agcaggtgtc aaaactgatg tcctcaatcc tttagaaagt ctgacagaag
    24121 aggacaccaa ggctggagaa aactacattt ccgtgatgga gaaaaacctc aaggctttga
    24181 aacaaacaac agaccaagaa ggcccagcaa tcgaacctga aaaggcagag gataccaaga
    24241 cagtccaaaa tggttacttc gaggatgcag ctgtcaagga ccgcaccttg agtgactatg
    24301 caggtaactg gcaatcagtt tatcctttcc ttgaagacgg cacgtttgac caagtctttg
    24361 actacaaggc taagttgact ggtaagatga cccaggctga gtacaaggct tactatacaa
    24421 aaggctatca gacagatgtg actaagatta acattactga taatactatg gaatttgttc
    24481 aaggtggaca aagcaagaaa tacacttaca agtatgtcgg taagaaaatt ttgacttaca
    24541 agaaaggcaa tcgtggcgtg cgtttcctct ttgaagccac agatgctgac gctggacaat
    24601 tcaagtatgt tcagtttagt gaccacaatg ttgccccagt taaggcagaa catttccata
    24661 tcttctttgg aggcacaagc caagaagccc tctttgaaga aatggacaac tggccaacct
    24721 actacccaga taacctatct ggccaagaaa tcgcccaaga aatgttggcg cattgatgag
    24781 aaatcgacta gttcataaga gctagtcggt tttttgatac tagatggcta acttcattat
    24841 agacctttca gaactttaaa caataaataa aactcttgaa atatctgggc ttatatgcta
    24901 gaatgtagtt agtgtataag gttcattaga acaccaaagc ccctaactag tgccatagtt
    24961 aagggctttt ttgacgtatc ttagcgattt aacgggtgtt tataggctag tcagtcggtc
    25021 tacttcttac catctagcca tttgcagacg aaatacaaga taattccagc tataacatct
    25081 gctataatag taagagcaag ctctggtata aggctcatta gtttcacctc ctctcacgaa
    25141 cccataggaa cgtaatcggt aaccgatgac aaaagtatta tatcacacta aatttagatc
    25201 atcaacctca cttaatgctt gaactattgt agattatatg ctaaaatgta gttaattgat
    25261 aaggttcatt agaacaccaa agcccctaac tatggccgta gttaagggct tttttgacgt
    25321 atcttagcga tttaacgggt gtttataggc tagtcagtcg gtctacttct tactatctag
    25381 ccatctgcag acgaaataca agataattcc agctataaca tccgctataa tagtaagagc
    25441 gagctctatg ataaggctca ttagtttcac ctcctctcac gaacccatag gaacgtaatc
    25501 ggtaaccgat gacaaaaata gtataccaca atacatttag atcatcaagg tcacttaatt
    25561 cttgaaatat agggtctagg cgacaaagtc tttaaaatca gaaaaacgta taatatcagg
    25621 tgtgcaaaaa cttgatacta tgcgttttat tgtgggaata tttgccccat ttctcctgaa
    25681 attgagtttt tgtccagcct ctgtttttgg ggttgctaag aaaataatgt catgtggtga
    25741 atatttgtaa atcagtcagc agacagaacg atactcttcg aaaatctctt cacatcatgt
    25801 cagcttcgtc tttccgtata tatgtgactg acttcatcag ttctatctac aacctcaaaa
    25861 cagtgtttcg agctgacttg atcaattttc aaatctgtac tttgagcaag ctgagactag
    25921 cttcctattt gattttcatt gaatatcaga aacccattct ccatcaaata attcgactgc
    25981 gtctaataat ttttggtctg gcacggtgtc agaaataaag gttgtgtatt tggggagggg
    26041 attaatttta aaaaatccag tcttgtaaaa tttagaacta tcaatcagta agatggtttc
    26101 atgggctttg tcaataatat tcttttttga aatagcttgg ctgagagaag cttcataaac
    26161 atattgatca tcaatacctc ttgctgaaca aaatgctaaa tcgatattaa aatgatctaa
    26221 taaagaattt tccttatcat agttgaccac ggaacaggat tgatgtttga cctcgccaga
    26281 tgtgataaag attttggagc tatctttaac agtttcagat agggtttgtg cagtatgtaa
    26341 accatttgta aaaataatca aattatcaag tttagaaaga tagggacaaa gttcgtagac
    26401 agtagtactg gaatccagat aaacacacat accagaccga ataaagtctt tagcgagact
    26461 agcgattagt cttttttgcc tagtactttc tccttcccgt atttgatgag aaagttcaat
    26521 tgtgttcata gaggacaggg tcacgtatcc gtgctttctt ttgataagac cttgattttc
    26581 taagaaaatt aaatcacgac gtaaggtact tgtgctggag aaagtgattt ctgccagctc
    26641 ttttacggca attctttttt tctttttgat aatttcaatc aattcaagta cacgttcatc
    26701 ttttatcata agctcctcct aatttatcat ttcaactata ttatagcaca aattggagga
    26761 atttgaatta tttttatgaa tattgggtta acatttgaac attattcaag taagcgttca
    26821 catattgaaa aaataaaacg tggggattat aataaagtta atcaaggacg aagagagaag
    26881 aaaaatggaa gcggttttag caatagattt aggtgcgact tctggaagag caatcgttgg
    26941 ttacctttct gaaaataaac tagtaatgga agaaataaat cgcttttcta atctacctat
    27001 tagagtaaaa gggcatttat cttgggatat tgactttcta ctagctaaaa ttcttgaaag
    27061 tatccgcttg gctaatacta gttacaagat tttatctatc ggtattgaca catggggagt
    27121 tgattttgga ctgattgata atgaaggtaa gctgttatca caacctgttc attatcgtga
    27181 tgaaagaaca aagggagtgt taaaggaaat atctgaaatg actgaattag aaaaactgta
    27241 ttcagagaca ggaaatcaga ttatggagat aaataccttg tttcaactct ttaaggcacg
    27301 tcaagaatct cctgactctt tctataagac caataa
//
LOCUS       DAVLTT010000021        26226 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLTT010000021 DAVLTT010000000
VERSION     DAVLTT010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26226
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.021"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            68..5371
                     /locus_tag="VYN15_001030"
     CDS             68..5371
                     /locus_tag="VYN15_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1452370.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSQVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPEVAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDIIAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRSDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPP
                     VAMTNYTKESMEALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKSKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(5538..7697)
                     /locus_tag="VYN15_001031"
     CDS             complement(5538..7697)
                     /locus_tag="VYN15_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HEV1452371.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(7694..8290)
                     /gene="recU"
                     /locus_tag="VYN15_001032"
     CDS             complement(7694..8290)
                     /gene="recU"
                     /locus_tag="VYN15_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV1452372.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            8356..8883
                     /locus_tag="VYN15_001033"
     CDS             8356..8883
                     /locus_tag="VYN15_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV1452373.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            8953..9282
                     /gene="gpsB"
                     /locus_tag="VYN15_001034"
     CDS             8953..9282
                     /gene="gpsB"
                     /locus_tag="VYN15_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV1452374.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            9303..9683
                     /gene="rnpB"
                     /locus_tag="VYN15_001035"
     ncRNA           9303..9683
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VYN15_001035"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9768..10925
                     /locus_tag="VYN15_001036"
     CDS             9768..10925
                     /locus_tag="VYN15_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV1452375.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKSLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            10938..12332
                     /gene="mapZ"
                     /locus_tag="VYN15_001037"
     CDS             10938..12332
                     /gene="mapZ"
                     /locus_tag="VYN15_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV1452376.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLEDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     PASSNTTSELKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            12408..13832
                     /gene="gndA"
                     /locus_tag="VYN15_001038"
     CDS             12408..13832
                     /gene="gndA"
                     /locus_tag="VYN15_001038"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV1452377.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            13844..14533
                     /locus_tag="VYN15_001039"
     CDS             13844..14533
                     /locus_tag="VYN15_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1452378.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            14631..15647
                     /gene="cbpC"
                     /locus_tag="VYN15_001040"
     CDS             14631..15647
                     /gene="cbpC"
                     /locus_tag="VYN15_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV1452379.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGLTWYYLNAGNGDMKTGWFQVNGKWYYAYSSGALAVNTTVDGYSVNYNG
                     EWVQ"
     gene            15769..16647
                     /gene="mvk"
                     /locus_tag="VYN15_001041"
     CDS             15769..16647
                     /gene="mvk"
                     /locus_tag="VYN15_001041"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV1452380.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            16629..17582
                     /gene="mvaD"
                     /locus_tag="VYN15_001042"
     CDS             16629..17582
                     /gene="mvaD"
                     /locus_tag="VYN15_001042"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV1452381.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            17569..18576
                     /locus_tag="VYN15_001043"
     CDS             17569..18576
                     /locus_tag="VYN15_001043"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV1452382.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLAIYGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIAAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            18560..19570
                     /locus_tag="VYN15_001044"
     CDS             18560..19570
                     /locus_tag="VYN15_001044"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV1452383.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAETCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            19648..20346
                     /locus_tag="VYN15_001045"
     CDS             19648..20346
                     /locus_tag="VYN15_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV1452384.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KIVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            20343..21338
                     /locus_tag="VYN15_001046"
     CDS             20343..21338
                     /locus_tag="VYN15_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1452385.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            21352..21984
                     /locus_tag="VYN15_001047"
     CDS             21352..21984
                     /locus_tag="VYN15_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1452386.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVMVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            21985..22227
                     /locus_tag="VYN15_001048"
                     /pseudo
     CDS             21985..22227
                     /locus_tag="VYN15_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            22152..22463
                     /locus_tag="VYN15_001049"
     CDS             22152..22463
                     /locus_tag="VYN15_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1452387.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            22488..22754
                     /locus_tag="VYN15_001050"
                     /pseudo
     CDS             22488..22754
                     /locus_tag="VYN15_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            22904..23098
                     /locus_tag="VYN15_001051"
     CDS             22904..23098
                     /locus_tag="VYN15_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452388.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYG"
     gene            23224..24049
                     /gene="cbpG"
                     /locus_tag="VYN15_001052"
                     /pseudo
     CDS             23224..24049
                     /gene="cbpG"
                     /locus_tag="VYN15_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
     gene            24068..25027
                     /gene="cbpF"
                     /locus_tag="VYN15_001053"
     CDS             24068..25027
                     /gene="cbpF"
                     /locus_tag="VYN15_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEV1452389.1"
                     /translation="MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGALKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSQAEKRVYYFEDQRSYHTLKTGWI
                     YEEGYWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQYLGNKWYYLHSSGAMATGWQNLGNKWYYLRSSGAMATGWYQEGSTWYYLNAS
                     NGDMKTGWFQVDGNWYYAYDSGALAVNTTVGGYYLNYNGEWVK"
     gene            complement(25155..26190)
                     /locus_tag="VYN15_001054"
                     /pseudo
     CDS             complement(25155..26190)
                     /locus_tag="VYN15_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         7898 a         4746 c         6050 g         7532 t
ORIGIN      
        1 gaggaaggag tattttttaa aaagaaaatg taaacgcttg ctcaaaaatg aaaggattta
       61 gaagtttatg aataaaggat tatttgaaaa acgttgtaaa tatagtattc ggaaattttc
      121 attaggtgtt gcttctgtta tgattggagc tgcattcttt gggacaagtc aggttcttgc
      181 agatagcgtg cagtctggtt ccacggcgaa cttaccagct gatttagcta ctgctcttgc
      241 aacagcaaaa gagaatgatg ggcgtgattt tgaagcgcct aaggtgggag aagaccaagg
      301 ttctccagaa gttacagatg gacctaagac agaagaagaa ctattagcac ttgaaaaaga
      361 aaaaccggct gaagaaaaac caaaagagga taaacctgaa gttgctaaac ctgaaacgcc
      421 taagacggta acccctgaat ggcaaacggt agagaaaaaa gaacaacagg gaacagtcac
      481 tatccgagaa gaaaaaggtg tccgctacaa ccaactatcc tcaactgctc aaaatgataa
      541 cgcaggtaaa ccagccctgt ttgaaaagaa gggcttgacc gttgatgcca atggaaatgc
      601 aactgttgat ttaaccttca aagatgattc tgaaaagggc aaatcacgct ttggtgtctt
      661 cttgaaattt aaagatacca ataataatgt ttttgtcggt tatgacaagg atggctggtt
      721 ctgggagtat aaatctccaa caactagcac ttggtataga ggtagtcgtg ttgctgctcc
      781 tgaaacagga tcaacaaacc gtctctctat cactctcaag tcagacggtc agctaaatgc
      841 cagcaataac gatgtcaatc tctttgacac agtgactcta ccagctgcgg tcaatgacca
      901 tcttaaaaat gagaagaaga tccttctcaa ggcgggctct tatggcaatg accgtacggt
      961 tgtcagcgtt aaaacagaca atcaagaagg cgtaaaagcg gatgatactc ctgcccagaa
     1021 agaaacaggt ccggttgttg acgatagcaa ggtgacttat gatacgatcc agtctaaggt
     1081 acttaaggca gtaattgacc aagccttccc tcgtgtcaag gaatacacct tgaatggaca
     1141 tactttgcca ggacaggtgc aacagttcaa ccaagtcttt atcaataacc accgaatcac
     1201 ccctgaagtc acttataaga aaatcaatga gacaacagca gagtacttga tgaagcttcg
     1261 cgatgatgct cacttaatca atgcggaaat gacagtacgc ttgcaagttg tggacaatca
     1321 attgcacttt gatgtgacca agattgtcaa ccacaatcaa gtcactccag gtcaaaagat
     1381 tgatgacgaa agaaaactac tttcttctat tagtttcctc ggcaatgctt tagtctctgt
     1441 ttctagtgat caaactggtg ctaagtttga tggggcaacc atgtcaaaca atacgcatgt
     1501 cagcggagat gatcatatcg atgtaaccaa tccaatgaag gatttggcta agggttacat
     1561 gtatggattt gtttctacag ataagcttgc tgctggtgtt tggagtaact ctcaaaacag
     1621 ctatggtggt ggttcgaatg actggactcg tttgacagct tataaagaaa cagtcggaaa
     1681 tgccaactat gtaggaatcc acagctctga atggcaatgg gaaaaagctt ataagggcat
     1741 tgttttccca gaatacacga aggaacttcc aagtgctaag gttgttatca ctgaagatgc
     1801 caatgcagac aagaaagtcg attggcagga tggtgccatt gcttatcgta gcattatgaa
     1861 caatcctcaa ggttgggaaa aagttaagga tatcatagct taccgtatcg cgatgaactt
     1921 tggttctcaa gcacaaaatc cattccttat gaccttggat ggtatcaaga aaatcaatct
     1981 ccatacagat ggtcttgggc aaggtgttct ccttaaagga tatggtagcg aaggccatga
     2041 ctctggtcac ttgaactatg ctgatattgg taagcgtatc ggtggtgtcg aagacttcaa
     2101 gaccctaatt gagaaggcta agaaatatgg agctcatcta ggtatccacg ttaacgcttc
     2161 agaaacttat cctgagtcta aatacttcaa tgaaaaaatt ctccgtaaga atccagatgg
     2221 aagctatagc tatggttgga actggctaga tcaaggtatc aacattgatg ctgcctatga
     2281 cctagctcat ggtcgtttgg cacgttggga agatttgaag aaaaaacttg gtgacggtct
     2341 cgactttatc tatgtggacg tttggggtaa tggtcaatca ggtgataacg gtgcctgggc
     2401 tacccacgtt cttgctaaag aaattaacaa acaaggctgg cgctttgcga tcgagtgggg
     2461 ccatggtggt gagtacgact ctaccttcca tcactgggca gctgacttga cctacggtgg
     2521 ctacaccaat aaaggtatca acagtgccat cacccgcttt atccgtaacc accaaaaaga
     2581 tgcttgggta ggggactaca gaagttatgg tggtgcagcc aactatccac tgctaggtgg
     2641 ctacagcatg aaagactttg aaggctggca aggaagaagt gactacaatg gctatgtgac
     2701 taacctcttt gctcatgacg tcatgactaa gtacttccaa cacttcactg taagtaaatg
     2761 ggaaaatggt acaccggtga ctatgaccga taacggtagc acctataaat ggactccaga
     2821 aatgcgagtg gagttggtag atgctgacaa taataaagta gttgtaactc gtaagtcaaa
     2881 tgatgtcaat agcccacaat atcgcgaacg tacagtaacg ctcaacggac gtgtcatcca
     2941 agatggttca gcttacttga ctccttggaa ctgggatgca aatggtaaga aactttctac
     3001 tgagaaggaa aagatgtact acttcaatac gcaggccggt acaacaactt ggacccttcc
     3061 aagcgattgg gcaaagagca aggtttacct ttacaagcta actgaccaag gtaagacaga
     3121 agagcaagaa ctaactgtaa aagatggtaa aattacccta gatcttctag caaatcaacc
     3181 atacgttctc tatcgttcga aacaaaccaa tcctgaaatg tcatggagtg aaggcatgca
     3241 catctatgac caaggattta atagcggtac cttgaaacat tggaccattt caggcgatgc
     3301 ttctaaggca gaaattgtca agtctcaagg ggcaaacgat atgcttcgta ttcaaggaaa
     3361 caaagaaaaa gttagtctca ctcagaaatt aactggcttg aaaccaaata ccaagtatgc
     3421 cgtttatgtg ggtgtcgata accgtagtaa tgccaaggcg agcatcactg taaacactgg
     3481 tgaaaaagaa gtgactactt ataccaataa gtctctcgcc ctcaactatg ttaaggccta
     3541 cgcccacaat acacgtcgta acaatgctac agttgacgat acaagttact tccaaaacat
     3601 gtacgccttc tttacaactg gatcggacgt atcaaatgtt actctgacat tgagtcgtga
     3661 agctggtgat caagcaactt actttgatga aattcgtacc tttgaaaaca attcaagcat
     3721 gtacggagac aagcatgata caggtaaagg caccttcaag caagactttg aaaatgttgc
     3781 tcagggtatc ttcccatttg tagtgggtgg tgtcgaaggt gtcgaagaca accgcactca
     3841 cttgtctgaa aaacacgatc catatacaca acgtggttgg aatggtaaga aagtcgatga
     3901 tgttatcgaa ggaaattggt cactcaagac aaatggacta gtgagtcgtc gtaacttggt
     3961 ttaccaaacc atcccacaaa acttccgctt tgaagctggt aagacctacc gtgtaacctt
     4021 tgaatacgaa gcaggatcag acaataccta tgcttttgta gtcggtaagg gagaattcca
     4081 atcaggtcgt cgtggtactc aagcaagcaa cttggaaatg catgaattgc caaatacttg
     4141 gacagattct aagaaagcca agaaggtaac cttccttgtg acaggtgcag aaacagggga
     4201 tacttgggta ggtatctact caactggcaa tgcaagtaat actcgtagtg attctggtgg
     4261 aaatgccaac ttccgtggtt ataacgactt catgatggat aatcttcaaa tcgaagaaat
     4321 taccctaaca ggtaagatgt tgacagaaaa tgctctgaag aactacttgc caccggttgc
     4381 catgactaac tacaccaaag agtctatgga ggctttgaaa gaggcggtct ttaacctcag
     4441 tcaggccgat gatgatatca gtgtggaaga agcgcgtgca gagattgcca agattgaagc
     4501 cttgaagaat gctttggttc agaagaaaac ggctttggta gcagatgact ttgcaagtct
     4561 tacagctcct gctcaggctc aagaaggtct tgcaaatgcc tttgatggaa acttatctag
     4621 tttatggcat acatcatggg gcggaggaga tgtaggcaag cctgcaacca tggtcttgaa
     4681 agaagcaact gaaatcactg gacttcgtta tgttccacgt ggatcaggtt caaatggtaa
     4741 cttgcgtgat gtgaaacttg ttgtgacaga tgagtctggc aaggagcata cctttactgc
     4801 aactgattgg ccagataaca ataagtcaaa agatattgac tttggtaaga caatcaaggc
     4861 taagaaaatt gtccttactg gtaccaagac ttacggagat ggtggcgata aataccaatc
     4921 tgcagcggaa ctcatcttta ctcgtccaca ggtagcagaa acacctcttg acttgtcagg
     4981 ctatgaagca gctttggcta aggctcagaa attaacagac aaagacaatc aagaggaagt
     5041 agctagcgtt caggcaagca tgaaatatgc gacggataac catctcttga cggaaagaat
     5101 ggtggaatac tttgcagatt atctcaacca attaaaagat tctgctacga aaccagatgc
     5161 tccaactgta gagaaacctg agtttaaact tagctcttta gcttccgatc aaggtaagac
     5221 gccagattat aagcaagaaa tagctagacc agaaacacct gaacaaatct tgccagcaac
     5281 aggtgagagt caatctgaca cagccctctt cctagcaggt gttagcctag ccctatctgc
     5341 tctctttgta gtaaaaacga agaaagacta gtatttagta aaacctctta acaagattac
     5401 ggaagcagtc tctatctttt ccaatgaggt ttatagtaca gaaaaagcct gagaagatgt
     5461 cttctcaggc ttttgttaag cacataaata caatagtgct atgacaaaat cacctagaaa
     5521 aatctgggtg ataaatgtta tggttgtgct ggttgaggat tctgattttg ttgatcaggg
     5581 gttgtatttg attgttgcgt attattgtta ggattggtag tcgtactatt atttgtgctt
     5641 ggagtggttg agctagactg tgaagttgaa ctatctgatg atgagcttga actttcagtt
     5701 gatgggggtt gttgtggagc aggtgagttc cacgtagaac gagcaccatt tttaaatacg
     5761 aattctccat ttctgtagag cccctctggt atattccaat cttctggatt gcttccttca
     5821 gacaggtagg tcatcataga gcggtaaact ttggcagcga ccgtaaggcc attgcctaca
     5881 agtggtgtca gacggttaga atagcctgtc catacagcca ttgaatattt acgcgtatag
     5941 ccagcaaata gttcatcagg tgctacaaat tgagaggtct tgatgtggtt ttcaatttcc
     6001 tcgtctgtat agttagaggt tcctgtttta ccagcctgag gaagccaagc aagataggca
     6061 tttcgtccag ttccataagt caagactgtt ttcatcatgt cggtcatcat ataggctgtc
     6121 gtttctttca tggcacgagt tccgacatta gagaactctt tttcactccc atcactaaag
     6181 acgactttat ggatatacat tggtttatag taagttccac catttgcaaa ggcagcgtaa
     6241 gcagcagcca tcttttcact acttgctcca tattttttgt ctgattcggt tgtgttactt
     6301 gaaatggcat ttgagtagtg aatacttggg tagtcgattc cgagaccatt taggaaagtc
     6361 ttggcgcggt tgagtccgac cttgtttaga gtttccacgg ctgggacgtt tcgcgattgt
     6421 tgcagggcgt attgcaaggt gatgttgcca aagtagcccc tatcccagtt ataaacagga
     6481 gtatttgtcc cagggtaatt atagggctca tcgtgaacga tagtagcagt tgaatcgtag
     6541 acaccgtact ccaaggcagg agcatagtct gtgatcggtt tcatagttga tccccagtcg
     6601 cggtttgttt ctactgcttg gttaattccg aaggaaacat tacttgactg atggcgtgct
     6661 cctagctggg caatgacttt accgttagaa acatcaacaa tggtagaagc gacttgcaat
     6721 tcatcgtctg gataggcaac gtattcgtct gtattgtaaa tatcccacag atgtttttga
     6781 gcttcttggt ctacatttgt gtagacatcc atcccagttg tgagcaggtt atagcctgtt
     6841 tcttcttcaa cttgattgat gacttccttg aggtaattat ccatgtaagc agggtaatta
     6901 cttgctgatt tgagactttg tagtccatca gtaattggtg tattgactgc tttctcatac
     6961 tgttcagcag agatgtagcc ttgatttttc atttcagata agaccaagtt tcggcggtct
     7021 tgggctgctt ctggatgtga ataggggtca tattggtttg gtgcctgagg cattccagcc
     7081 agcaaggcta actgaggtaa acttaaatta ttgaggtctt taccatagta gttttgagct
     7141 gctgtctgca ttccatagtt cccattagac atgtagacct tatttatata gtaggtcaag
     7201 atttcttgct tggttgcttt ttgttctaac tgaatcgcta accaagcttc ctgagcctta
     7261 cgagaaatag tctggtcgga agtcgaagtt gaaaagtaag tcaacttaat caactgttgg
     7321 gtgagagttg atccaccttg gagggaattg ctttgcagat tgcgcaagaa agctcccagg
     7381 atacggatgg tatcaatccc cctgtggtcg aagaagcgat ggtcttcgat agaaacgatt
     7441 gccttaacca aatctgtggg aatatcatta gcttgggcat tgacgcggcg ttcagaaccc
     7501 aagtcagcaa tgagttgatt tttattgtcg tagattttac tagaagttgt tgcaactagt
     7561 ttactctcgg ataggctagg agccttgcta acgtagtaga aaaaaactcc tccgcctaag
     7621 acaatggctg cgataaccaa gcttaagaag ctaatgctca gatacttgat taggcgcaga
     7681 atcgttggtt tgttcatctt gttttaccac ctaataaatg ttctttgata acattgagat
     7741 aaggaatttg agggaaggca ccagccttga tttcatatcc atattctcga atatattcaa
     7801 gtggcattga tttttgtccc ttatcttgat gatagaagcg aatcaaatcg aatgccggca
     7861 ataagtaggt ttcttgctga gaagaaaagt gaagaaggac aaagcagatt ccttgttggg
     7921 caaggacttg ttccatatgc tgaatctgat gtggatgaaa atttttcatc ggaatcgcac
     7981 gtttttgttt tgtttccttg acttcaaagt cgatgtaata tccattataa acgccagaat
     8041 agtccgtcgt tgaagcttgt cgaaaatagg cttcaacaat cttggcacga cttcgttgtg
     8101 gatagtccac ttgtacgatt tgaataggag ttggtttctt atgtataaca gccaagccct
     8161 gagacaaata gtagtcgttg gtagcattga tcatcttttc aaaagacatt cctcgatttg
     8221 cgaaattttt gggttgagaa agagatgttt gtcttttttg tgatgaaact ttatgtggat
     8281 agttgaccat aattctcctt attggtacaa taacatcact ttattatacc ataatttgca
     8341 cagaaagggt taaaaatggc tacagctttg gttttaggct attctgcttt tgatttgggt
     8401 ttattttctg ataaggatcc tcgtcttaaa ttgattaaaa aagcgatacg taaagattta
     8461 gaggctatgg cagcagatgg ggtgtcttgg cttgtgttta caggaagttt gggttttgaa
     8521 tattgggttt tagaggttgc tcaggagatg aaaaccgaat acggtttcca gttggccacc
     8581 atttttgctt ttgaaaccca tggggaaaat tggaatgaag gcaatcagat gaaactgagt
     8641 cgctttaagc aggtagactt tgtcaaatat gcttatcctc gttatgaaca caaggggcag
     8701 ttaagagatt accagcagtt tttgctggaa aacacgacta gttcctatct tttttatgat
     8761 gaagaaaatg aaacaaaact agcttatttt taccaaaaga tgaaaaatca agaggactat
     8821 tttataaaga gattaacatt tgatgaatta aatgaacttg ctgaaaattt ttccgaaaat
     8881 tgaagctttg accttgattt ttgtttgcct ttttttatat aataatacta gcaagcgaga
     8941 atggagagag acatggcaag tattattttt tcagcgaaag atatttttga acaagagttt
     9001 ggacgtgagg tccgtggcta taataaagta gaagttgacg agtttttaga cgatgtcatc
     9061 aaggactatg aaacctatgc tgccttggtc aagtcacttc gtcaggaaat tgcggatttg
     9121 aaggaagaat taactcgtaa accgaaacct tcaccagttc aagcagaacc ccttgaagcg
     9181 gcaattacaa gttctatgac gaattttgat attttgaaac gcctgaatag attggaaaaa
     9241 gaagtttttg gtaaacaaat tttagataac tcagattttt aagtagttat ttgagatgtg
     9301 caatttttgg ataatcgcgt gaggagaatt gtttctcatg aggaaagtcc atgctagcac
     9361 aggctgtgat gcctgtagtg tttgtgctag gcgaaaccat aagcctaggg acgagaaatc
     9421 gttacggcag ttgaaatggc taagtccttg gataggtcag agtaggcttg aaagtgccac
     9481 agtgacggag tctttctgga aacagagaga gtggaacgcg gtaaacccct caagctagca
     9541 acccaaattt tggtcggggc atggagtacg cggaaacgaa cgtagtattc tgactgctat
     9601 cagctagagc tgttagtggt agacagatga ttatcgaagg aagtggtcct agtcacttct
     9661 ggaacaaaac atggcttata gaaaattgca tataggttgg ggctgagaaa ttttctcaac
     9721 ctcatttttt aaagtggaca tatagaaagg tcttgcaaga ctgtaacatg aaaaaagaat
     9781 ttaatttaat tgcaactgtg gcagcagggc ttgaggctgt cgttggtcgt gaagtgcgag
     9841 agttgggcta cgattgtcag gttgaaaatg gacgtgttcg ttttcaagga gacgtgagag
     9901 ctattatcga aaccaacctt tggcttcggg cagcagatcg tatcaaaatt atcgtaggaa
     9961 cgttcccagc taagactttt gaagagctat ttcagggagt tttcgcttta gattgggaaa
    10021 attatttacc acttggagct cggttcccga tttcaaaagc taaatgtgtt aagtccaaac
    10081 ttcacaatga gcccagtgtt caggctattt ctaagaaagc tgttgtcaag aaattgcaga
    10141 aacactatgc tcgcccagaa ggggttcctc tgatggagaa tggcccagag tttaagattg
    10201 aagtctctat tctcaaagat gtggcaactg tcatgattga tacgaccggg tctagcctct
    10261 ttaaacgtgg ttatcgtacc gaaaaaggtg gcgctcctat caaggaaaat atggcagcag
    10321 ccattttaca actttctaac tggtatccag acaagtcttt gattgatccg acctgtggtt
    10381 cggggacttt ctgtattgag gcagttatga ttgctagaaa gatggcgcca ggtcttcgtc
    10441 gctcttttgc atttgaggaa tggaactgga tcagcgatcg cttgattcaa gaagtgcgca
    10501 cagaagcagc taaaaaagta gaccgtgagc ttgagctgga tatcatgggc tgtgatattg
    10561 atgctcgcat ggtggaaatt gctaaggcca atgctcaggc agctggtgtt gcaggagaca
    10621 ttacttttaa gcagatgcgc gtgcaggatt tacgttccga taaaatcaat ggagtaatca
    10681 tttccaatcc gccttatggt gaacgtttgt cagatgatgc aggggtgact aagctctatg
    10741 ctgagatggg gcaagtattt gcaccgctga aaacttggag caaatttatc ctgactagtg
    10801 atgaagcttt tgaaagcaag tatggtagcc aagcagataa gaagcgtaag ttatacaacg
    10861 gaaccttgaa agtggatctg tatcaatatt ttggtcagcg tgtcaaacgg caagaggtaa
    10921 aatagaaagg gatactcatg agtaaaaaaa gacgaaatcg tcaaaaaaaa gaaggtcaag
    10981 aaccgcaatt tgattttgat gaagcaaaag agctaacagt tggtcaagct attcgtaaaa
    11041 atgaagaagt ggaagcagga gtcttgcctg aggattccat tttggacaag tatgttaagc
    11101 aacacagaga tgaaattgag gcggataagt ttgcgactcg tcaatacaaa aaagaggagt
    11161 tcgttgaaac tcagagtctg gatgatttaa ttcaagagat gcgtgaggct gttgagaagt
    11221 cagaagcttc ttcggaggaa gttccatctt ctgaagacat cttactaccc ttgcctctgg
    11281 acgatgagga gcaaggcttg gatcctctat tgctagagga tgaaaatcca acagaaatga
    11341 ctgaagaagt ggaagaggag caaaaccttt ctcgtctgga tcaagaggac tcagaaaaga
    11401 aaagtaaaaa aggctttatt ttgaccgttt tggcgcttgt atcagtaatt atttgtgtca
    11461 gtgcttatta tgtctaccgt caagtggctc gttcgactaa ggaaattgaa acttctcaat
    11521 caactacagc caatcaatca gatgtggatg attttaatac actttatgac gccttttaca
    11581 cagatagcaa taaaacggct ttgaaaaata gccagtttga taaactgagt caactcaaaa
    11641 ccttgcttga taaactggaa ggtagtcgtg aacatacgct agccaaatct aagtatgata
    11701 gtctagcaac gcaaatcaag gccattcaag atgtcaatgc tcaatttgag aaaccagcta
    11761 ttgtggatgg tgtgttggat accaatgcca aagccaaatc ggatgctaaa tttacagata
    11821 ttaaaactgg aaatacggag cttgataaag tgctagataa ggctatcagt cttggtaaga
    11881 gccagcaaac aagtacttct agctcaagtt caagtcaaac tagcagctca agctctagtc
    11941 cagcaagttc aaatacgact agtgagctaa aaccaagtag ttcaaatgag actagaagta
    12001 gtcgcagtga agtcaatatg ggtctctcga gtgcaggggt tgctgttcaa agaagtgcca
    12061 gtcgtgttgc ctataatcag tctgctattg atgatagtaa taactctgcc tgggattttg
    12121 cggatggtgt cttggaacaa attctagcga cttcacgttc acgtggctat atcactggag
    12181 accaatatat ccttgaacgt gtcaatatcg ttaacggcaa tggttattac aacctctata
    12241 agccagatgg aacctatctc tttaccctta actgtaagac aggctacttt gtcggaaatg
    12301 gcgctggtca tgcggatgac ttggactact aagcagtcgt tacaaaattc tttcttttca
    12361 aaagtaaaaa tgataaaata aaacaaatga aacaagagga gtgtcaaatg acaaaagcta
    12421 actttggtgt cgtaggtatg gccgtaatgg gtcgtaacct tgcccttaat attgaatcac
    12481 gtggttacac agttgctatc tacaaccgta gtaaagaaaa aacggaagat gtgattgctt
    12541 gccatcctga aaagaatttt gtaccaagct atgacgttga aagttttgta aactcaatcg
    12601 aaaaacctcg tcgtatcatg ctgatggttc aagctggacc tggtacagat gctactatcc
    12661 aagcccttct tccacacctt gacaagggtg atatcttgat tgacggagga aacactttct
    12721 acaaagatac catccgtcgt aatgaagaat tggcaaactc aggtatcaac tttatcggta
    12781 ctggagtttc tggtggtgaa aaaggtgccc ttgaaggtcc ttctatcatg cctggtggac
    12841 aaaaagaggc ctacgaattg gttgcggatg ttcttgaaga aatctcagct aaagcaccag
    12901 aagatggcaa accatgtgtg acttacatcg gccctgatgg agctggtcac tatgtgaaaa
    12961 tggttcacaa tggtattgag tacggtgata tgcaattgat cgcagaaagc tatgacttga
    13021 tgcaacactt gctaggcctt tctgcagagg atatggctga aatctttact gagtggaaca
    13081 agggtgaatt agacagctat ttgatcgaaa tcacagctga tatcttgagc cgtaaagacg
    13141 atgaaggcca agatggacca atcgtagact acatccttga tgctgcaggt aacaagggaa
    13201 ctggtaaatg gacgagccaa tcatctcttg accttggtgt accattgtca ctgattactg
    13261 agtcagtgtt tgcacgctac atttcaactt acaaagaaga acgtgtacat gctagcaagg
    13321 tgcttccaaa accagctgcc ttcaactttg aaggagacaa ggctgaattg attgaaaaaa
    13381 tccgtcaagc cctttacttc tcaaaaatca tttcatacgc acaaggattt gctcaattgc
    13441 gtgtagcctc taaagaaaac aactggaact tgccatttgc agatatcgca tctatctggc
    13501 gtgatggctg tatcatccgt tctcgttttt tgcaaaagat tacagatgct tacaaccgcg
    13561 atgcagatct tgccaacctt cttttggacg agtacttctt ggatgttact gctaagtatc
    13621 aacaagcagt gcgtgatatc gtagctcttg cggttcaagc tggtgtgcca gtgccaactt
    13681 tctcagcagc tattacttac tttgatagct accgttcagc tgaccttcca gctaacttga
    13741 tccaagcaca acgtgactac tttggtgctc acacttacca acgtaaagac aaagaaggaa
    13801 ccttccacta ctcttggtat gacgaaaaat aagtaggtca gccatgggga aacggatttt
    13861 attacttgag aaagaacgaa atctagctca ttttttaagt ttggaactcc agaaagagca
    13921 gtatcgggtt gatctggtag aggaggggca aaaagccctt tccatggctc ttcagacaga
    13981 ctatgatttg attttattga acgttaatct gggagatatg atggctcagg attttgcaga
    14041 aaaattgagt cgaactaaac ctgcctcagt catcatgatt ttagatcatt gggaagactt
    14101 gcaagaagag ctggaagttg ttcagcgttt tgcagtttca tacatctata agccagtctt
    14161 tatcgaaaat ctggtagcgc gtatttcggc gatcttccga ggtcgggact tcattgatca
    14221 acactgcagt ctgatgaaag ttccaaggac ctaccgcaat cttaggatag atgttgaaca
    14281 tcacacggtt tatcgtggtg aagagatgat tgctctgacc cgccgtgagt atgacctttt
    14341 ggcgacactt atgggaagca agaaagtatt gactcgtgag caattgttgg aaagtgtttg
    14401 gaagtatgaa agtgcgaccg agacaaatat cgtagatgtc tatatccgct atctacggag
    14461 caagcttgat gttaaaggcc aaaaaagcta cattaaaacc gtgcgtggtg ttggatatac
    14521 catgcaagaa tagaaaagca gttgcagttg tgtaactgct tttttgagga gtttttatat
    14581 attgacatgc agtcgggtct ttgctacaat cgttttagga ggatatatag atgaaacttt
    14641 tgaaaaaaat gatgcaagtt ctactagcag tctttttctt tggtttgcta gctacaaata
    14701 cggtatttgc gaataccaca ggtggccgat ttgttgataa ggataataga aaatattatg
    14761 taaaagatga tcataaagca atctattggc ataaaataga cggtaaaact tactattttg
    14821 gtgatattgg agagatggtt gtcggttggc aatacttaga aattcctgga acaggttatc
    14881 gtgataattt attcgataac caaccagtta atgaaattgg ccttcaggag aagtggtact
    14941 attttggaca agatggtgct ttgctagaac aaacagataa acaagtacta gaggcaaaaa
    15001 cgtctgaaaa tacaggaaaa gtatacggtg aacaatatcc tctatctgct gaaaagagaa
    15061 cttattattt tgataataat tatgctgtaa agacaggctg gatttatgaa gacggcaatt
    15121 ggtattattt aaataagcta ggaaattttg gcgatgattc ttacaatcca ctaccaattg
    15181 gtgaagttgc taagggttgg actcaagatt ttcatgttac tattgacatt gatagaagca
    15241 aacctgctcc atggtactac ctagatgctt caggtaagat gcttacagat tggcaaaaag
    15301 taaacggaaa atggtattat tttggctcct ctggttctat ggcaacaggt tggaaatatg
    15361 tacgaggcaa atggtattac ttagataata aaaatggtga tatgaaaaca ggatggcaat
    15421 accttggtaa caagtggtac tacctccgtt catcaggagc tatggtaact ggctggtatc
    15481 aagatggttt aacttggtac tacctaaatg caggtaatgg agacatgaag acaggttggt
    15541 tccaggtcaa tggcaaatgg tactatgctt atagctcagg tgccttggca gtgaatacga
    15601 ccgtagatgg ctattctgtc aactataatg gcgaatgggt tcaataatga aagaagcgat
    15661 tgcgaatgga aacaatcgct ttttttgtga aaatataata aaatagatag gaaagaatta
    15721 atacttgtat gaaaaataag acgttttttc gtctagtaaa aggaaaaaat gacaaaaaaa
    15781 gttggtgtcg gtcaggcaca tagtaagata attttaatag gggaacatgc ggtcgtttac
    15841 ggttatcctg ccatttccct gcctcttttg gaggtggagg tgacctgtaa ggtagttcct
    15901 gcagagagtc cttggcgcct ttatgaggag gataccttgt ccatggcggt ttatgcctca
    15961 ctggagtatt tgaatatcac agaagcctgc attcgttgtg agattgactc ggctatccct
    16021 gagaaacggg ggatgggttc gtcagcggct atcagcatag cggccattcg tgcggtattt
    16081 gactactatc aggctgatct gcctcatgat gtactagaaa tcttggtcaa tcgagctgaa
    16141 atgattgccc atatgaatcc tagtggtttg gatgctaaga cctgtctcag tgaccaacct
    16201 attcgcttta tcaagaacgt aggatttaca gaacttgaga tggatttatc cgcctatttg
    16261 gtgattgccg atacgggtgt ttatggtcat actcgtgaag ccatccaagt ggttcaaaat
    16321 aagggcaagg atgccctacc gtttttgcat gccttgggag aattaaccca gcaggcagaa
    16381 gttgcgattt cacaaaaaga tgctgaaggg ctgggacaaa tcctcagtca agcacattta
    16441 catttaaaag aaattggtgt cagtagcctt gaggcagact ctttggttga aacagctctt
    16501 agtcatggtg ctctgggtgc caagatgagc ggtggtgggc taggaggttg tatcatagcc
    16561 ttggtaacca atttgacaca cgcacaagaa ctagcagaaa gattagaaga gaaaggagct
    16621 gttcagacat ggatagagag cctgtgacag tacgttccta cgcaaatatt gctattatca
    16681 aatattgggg aaagaaaaaa gaaaaagaga tggtgcctgc tactagcagt atttctctaa
    16741 ctttggaaaa tatgtataca gagacgacct tgtcgccttt accagccaat gtaacagctg
    16801 acgaatttta catcaatggt cagctacaaa atgaggtcga gcatgccaag atgagtaaga
    16861 ttattgaccg ttatcgtcca gctggtgagg gctttgtccg tatcgatact caaaacaata
    16921 tgcctacggc agcgggcctg tcctcaagtt ctagtggttt gtccgccctg gtcaaggctt
    16981 gtaatgctta tttcaagctt ggattggata gaagtcagtt agcgcaggaa gccaagtttg
    17041 cctcaggctc ttcttctcgg agtttttatg gaccactagg agcctgggat aaggatagtg
    17101 gagaaattta ccctgtagag acagacttga aactagctat gattatgttg gtgctagagg
    17161 acaagaaaaa accaatctct agccgtgacg ggatgaaact ttgtgtggaa acctcgacga
    17221 ctttcgacga ctgggttcgt cagtctgaga aggactatca ggatatgctg atttatctca
    17281 aggaaaatga ttttgccaag attggagaat taacggagaa aaatgccctg gctatgcatg
    17341 ctacgacaaa gactgctagt ccagcctttt cttatctgac ggatgcctct tatgaggcta
    17401 tggactttgt tcgtcagctt cgtgagaaag gagaggcctg ctactttacc atggatgctg
    17461 gtcccaatgt taaggtcttc tgtcaggaga aagacttgga gcatttgtca gaaattttcg
    17521 gtcagcgtta tcgcttgatt gtgtcaaaaa caaaggattt gagtcaagat gattgctgtt
    17581 aaaacttgcg gaaaactcta ttgggcaggt gaatatgcta ttttagagcc agggcagtta
    17641 gctttgataa aggatattcc catctatatg agggctgaga ttgctttttc tgacagctac
    17701 cgtatctatt cagatatgtt tgatttcgca gtggacttaa ggcccaatcc tgactacagc
    17761 ttgattcaag aaacgattgc tttgatggga gacttcctcg ctgttcgcgg tcagaattta
    17821 agaccttttt ctctagcaat ctatggcaaa atggaacgag aagggaaaaa gtttggtcta
    17881 ggttctagtg gcagcgtcgt tgtcttggtt gtcaaggctt tactggctct ctataatctt
    17941 tcggttgatc agaatctctt gttcaagctg actagtgctg tcttgcttaa gcgaggagac
    18001 aatggttcca tgggcgacct tgcctgtatt gcggcagagg atttggttct ctaccagtca
    18061 tttgatcgcc agaaggtggc tgcttggtta gaagaagaaa acttggcgac agttctggag
    18121 cgtgattggg gattttcaat ttcacaagtg aaaccaactt tagaatgtga tttcttagtg
    18181 ggatggacca aggaagtggc tgtatcgagt cacatggtcc agcaaatcaa gcaaaatatc
    18241 aatcaaaatt ttttaacttc ctcaaaagaa acggtggttt ctttggtcga agccttggaa
    18301 caggggaaat cagaaaagat tatcgagcaa gtagaagtag ccagcaagct tttagaaggc
    18361 ttgagtacag atatttacac gcctttgctt agacagttga aagaagccag tcaagatttg
    18421 caggccgttg ccaagagtag tggtgctggt ggtggtgact gtggcatcgc cctgagtttt
    18481 gatgcgcaat caaccaaaac cttaaaaaat cgttgggccg atctggggat tgagctctta
    18541 tatcaagaaa ggataggaca tgacgacaaa tcgtaaggac gagcatatcc tctatgccct
    18601 tgagcagaaa agttcctata atagctttga tgaggtggag ctgattcatt cttccttgcc
    18661 tctttacaat ctggatgaaa tcgatctttc gacagagttt gctggtcgaa agtgggactt
    18721 tcctttttat atcaatgcca tgactggtgg aagtaataag ggaagagaaa tcaatcaaaa
    18781 gctggctcag gtggcggaaa cctgtggtat tttatttgta acgggttctt atagcgcagc
    18841 cctcaaaaat ccaacggatg attctttttc tgtcaagtct agtcatccca atctcctcct
    18901 tggaaccaat attggattgg acaagcctgt cgagttagga cttcagactg tagaagagat
    18961 gaatcctgtt ctattgcaag tgcatgtcaa tgtcatgcag gaattactca tgcccgaggg
    19021 agaaaggaag tttagaagct ggcaatcgca tctagcagat tatagcaagc aaattcccgt
    19081 tcctattgtc ctcaaggaag tgggctttgg aatggatgcc aagacaatcg aaagagccta
    19141 tgaattcggt gttcgtacag tggacctatc gggtcgtggt ggcaccagct ttgcctatat
    19201 cgaaaaccgt cgtagtggcc agcgtgatta cctcaatcaa tggggtcagt ctaccatgca
    19261 ggcccttctc aatgcccaag aatggaaaga taaggtcgaa ctcttggtta gtggaggggt
    19321 tcggaatccg ctggatatga ttaagtgctt ggtttttggt gctaaggctg tgggattgtc
    19381 acgaaccgtt ctggaattgg ttgaaaccta cacagttgaa gaagtgattg gcattgtcca
    19441 aggctggaaa gcagatctac gcttgattat gtgttccctt aactgtgcca ccatagcaga
    19501 tctacaaaaa gtagactatc ttctttatgg aaaattaaaa gaagcaaatg atcagatgaa
    19561 aaaggcgtaa ccagcgcctt tttttccatc ctcagactga ggtgactttt ttgaattgtg
    19621 ataaaataga agggagagga tgaacctatg agaaaattta aaatcttttt atttatcgaa
    19681 gcctgtcttc tgacaggagc tctgattttg atggtatcag agcatttttc gcgttttctg
    19741 ctgatactat tcctcttttt gcttttgatt cgctactaca ctggtaaaga gggaaataat
    19801 cttcttttag tagcggcaac cattctcttc tttttcatcg ttatgctcaa tccttttgtg
    19861 attctagcta tttttgttgc ggttatctat agcctctttc ttctttaccc gatgatgaac
    19921 caggaaaaag agcagaccaa tttggttttt gaagaggtcg tgacggttaa gaaggagaaa
    19981 aatcgttggt ttggaaatct tcatcatttt tcaagctacc agacttgcca attcgatgat
    20041 atcaatctct ttcgcttcat gggcaaggac actattcatc tggagagggt catcttaacc
    20101 aatcatgaca atgtcattat cctcagaaag atagtaggaa cgaccaaaat catcgtacct
    20161 gtagatgtgg aagtcagtct cagcgttaac tgtctctatg gggatttgac ttttttcaac
    20221 cagcccaagc gagccctccg caatgaacac tatcatcaag aaacaaaaga ctatctcaag
    20281 agtaacaaga gtgtcaagat tttcttgacc actatgattg gtgatgtgga ggtggttaga
    20341 ggatgaaaaa acaagcctat gtcattattg ctctcacctc cttcctgttt gtcttttttt
    20401 tctcccacag cttgctggaa atacttgatt ttgactggtc tatctttttg cacgatgtcg
    20461 aaaaaacaga aaaatttgtc tttttattgt tggttttcag catgtccata acctgtctct
    20521 tagccctgtt ttggcgaggg atcgaagagc tttctctaag aaaaatgcag gctaatctca
    20581 agcgtttatt ggcagggcaa gaagtagttc aggttgtaga tccagatttg gatgccagtt
    20641 tcaagtcctt atcaggtaaa cttaaccttt tgacagaggc tcttcaaaaa gcagaaaatc
    20701 agagtcttgc tcaggaagag gaaatcatcg agaaggaacg gaagcgaatt gctcgggatt
    20761 tgcacgatac agtcagtcag gagttgtttg cggcccacat gattttatcg ggtatcagtc
    20821 agcaggcttt gaaattggat agagaaaaga tgcagaccca gttgcagagt gtcacagcta
    20881 ttttagaaac agcccagaag gatttgcggg ttttgctctt gcatttgcga ccagttgaac
    20941 tggagcagaa gagcttgata gaagggattc aaattctctt aaaagagctt gaggacaaga
    21001 gtgatcttag ggttagtctc aagcagaata tgacgaaatt gcctaagaaa atcgaggagc
    21061 atattttccg tatcctgcaa gagttgatta gcaatacgct ccgccatgcc caggcatctt
    21121 gcctagatgt ctacctctat cagacagatg ttgaattgca actgaaggtg gtggacaatg
    21181 ggattggttt ccagttaggg agcttagacg acttgagtta tggactgcga aatatcaagg
    21241 agcgggttga agatatggca gggacggttc agttattaac agctcccaag caagggctgg
    21301 cagttgatat ccgtattccc ctgttagata aggaatgata aaggagtaaa gatgaaaatt
    21361 ttactagtag atgaccatga aatggtccgt ttgggcttga aaagctactt tgacctccaa
    21421 gacgatgtag aagttgtggg tgaggcgtcc aacgggtctc aagggattga cttggccttg
    21481 gaactgcgtc cagatgtcat ggtcatggat attgtcatgc ctgagatgaa tgggattgac
    21541 gcgaccttag caatccttaa agaatggcct gaagccaaga ttttgattgt gacctcttat
    21601 ttggacaatg aaaaaatcat gccagtctta gatgctggtg ccaaaggcta tatgctcaag
    21661 acttctagtg cagatgaatt gcttcatgcc gtcagtaagg tagctgctgg cgagctggcc
    21721 attgagcaag aggttagcaa gaaggttgaa taccaccgca atcatatgga acttcatgaa
    21781 gaattgactg cgcgtgagcg agatgttctc caactcatcg ccaagggcta cgaaaatcag
    21841 cgcatcgcag atgacctctt tatctctctc aagacggtca agacccacgt gtccaatatt
    21901 cttgccaaac ttgaagtcag cgatcgtacc caggcggctg tctatgcctt tcagcaccat
    21961 ttggtggggc aagaggagtt ttagatgagt ttagcagatt tacttgagga gctagaagca
    22021 gcaaaagact ctaaaaaagc aaggcccatg gaagcctata tgcgccatca attttctttt
    22081 ctaggtattg cggtgcctga aagaaataaa ctctataaaa atatttacta gaagcgaaaa
    22141 aaacaaagat tatcgattgg gattttgcag acacttgctg ggaaaaggag cctagaaaat
    22201 accaatatgt ggctgctaac tatttgaaag caatgcagtc ttatctaaag gaaaccgatt
    22261 tgcctaagct agagcagtta gtcgtgacaa aatcctggtg ggacacggta gatatcctag
    22321 atcgagtagt agggagtttg gtgtatgaac accctgaact agaagaaata atcttaatac
    22381 tcttcgaaaa tctcttcaaa ccacgtcagc tctatctgca acctcaaaac agtgttttga
    22441 gcaatctgcg gctagcttcc tagtttgctc tttgattttc attgagtata aaatggagcc
    22501 tatcagataa tatctggctg agacgtgtcg ctattgacca ccagttgtta agaaaagaga
    22561 agaccaatac tcaattaatg gaaaagattc tacttcataa cttgaaccaa acagaatttt
    22621 ttatcaataa agccattggc tggattctgc gagactactc caaaacgaat ccaacttggg
    22681 taacatgctt tattgatgaa aacaaggaaa gaatggctga acttagtatc aaagaagcaa
    22741 gcaagtacct ctagcgtgat tgaaaagcgc agtcattaat tgaaaagttt gcctgtttat
    22801 gtgataatgg agggtattta aagaaggtgg tagatttctt gattctatag tagattgaga
    22861 aatttagaat agtacgctat aattacatta ggaggataca ataatgaaga aaactgttta
    22921 taaaaaattg ggtatttcaa ttattgcgag tactttattg gctagccagt tatcgacagt
    22981 atctgctttg agtgttattt ctagtacagg tgaagaatat gaggtaagtg agacactaga
    23041 aaaaggtcca gagtctaatg attcttcatt atctgagatt tcaccaacgt atggttaata
    23101 ctaccaaaag caatcagaag tattatcggt aatgatgatt tgattaaaat tgataatact
    23161 ttacagtatc catattcgac ttcagctatg gttttatcta agtattatgg agtagccgat
    23221 ggaatgaatg tagaagggag gggaagtgcg aattttatta aagataatgt gttaattaca
    23281 gcggctcaca actactacag acatgactat gggaaagaag cggatgatat ttatgttctt
    23341 ccggctgtta gtccaagtca agaactattt ggaaagatca aagtaaagga agttcgttat
    23401 ttgaaggaat ttagaaattt aaattctaag gatgcaaggg aatatgactt ggctttatta
    23461 attctagaaa agcccattgg tgcaaaatta gggactttgg gtcttcctac tagtcaaaaa
    23521 aatttgacag gaataactgt gactatcaca ggctatccat catataattt taaaattcat
    23581 caaatgtata cagataaaaa acaagtttta agtgatgatg gcatgttctt ggattaccaa
    23641 gttgatactt tagaggggtc tagtggatct acagtttatg atgctagtca ccgtgtagta
    23701 ggagtgcata ctttaggaga tggagctaat taaattaaca gtgcagttaa attaaatgaa
    23761 cgaaatttgc catttattta tttattcggt tcttaaaggt tactctcttg aaggatggaa
    23821 gaaaataaat ggtagttggt actattatag acaacatgat aaacaaacgg gttggcagga
    23881 gataaatgat acttggtatt atttagacag ttccggtaag atgcttacag attggcaaaa
    23941 agtaaatgga aactggtatt atctcaattc aaatggagca atggttacag gtagccaaac
    24001 tatcgatggt aaagtttata acttcgcttc atctggtgag tggatttgat gttggaggat
    24061 atataaaatg aagcttttga aaaaaatgat gcaagtcgca ctagccacat ttttcttcgg
    24121 tttgctaggg accagtacag tatttgcaga tgattctgaa ggatggcagt ttgtccaaga
    24181 aaatggtaga acctactaca aaaagggggc tctaaaagaa acctactgga gagtgataga
    24241 tgggaagtac tattattttg atcctttatc cggagagatg gttgtcggct ggcaatatat
    24301 acctgctcca cacaaggggg ttacgattgg tccttctcca agaatagaga ttgctcttag
    24361 accagattgg ttttattttg gtcaagatgg tgtcttacaa gaatttgttg gcaagcaagt
    24421 tttagaagca aaaactgcta cgaataccaa caaacatcat ggggaagaat atgatagcca
    24481 agcagagaaa cgagtctatt attttgaaga tcagcgtagt tatcatactt taaaaactgg
    24541 ttggatttat gaagagggtt attggtatta tttacagaag gatggtggct ttgattctcg
    24601 catcaacaga ttgacggttg gagagctagc acgtggttgg gttaaggatt accctcttac
    24661 gtatgatgaa gagaagctaa aagcagctcc atggtactat ctagatccag caactggcat
    24721 tatgcaaaca ggttggcaat atctaggtaa taagtggtac tacctccatt cgtcaggagc
    24781 tatggcaact ggctggcaaa accttgggaa caaatggtac tatctccgtt catcaggagc
    24841 tatggcaact ggttggtatc aggaaggttc gacttggtac tatctaaatg caagtaatgg
    24901 agatatgaaa acaggctggt tccaagtcga tggtaactgg tactatgcct atgattcagg
    24961 tgctttagct gttaatacca cagtaggtgg ttactactta aactataatg gtgaatgggt
    25021 taagtaatga aggctaattg taaactgtga tggatactta actttgtata ataggtggat
    25081 aaaagtcttc acaatcaaaa aacgcatagt atcaaggttt ttctgtactg ccccccaaaa
    25141 gttagacaaa taatttatcc aaaggattta gttctgtact gcacaggact aagtcctttt
    25201 agttttacct taattctctt gttgttgtaa taatcaatat agtctataat ggcttgttcc
    25261 aattgattaa gtgatttaaa tgttttctca tagccataaa acatttccga tttcagaatc
    25321 ccaaagaagg actccaccat agtgtttctc tgtgaatgcc tgttccaaca ttgtttgtac
    25381 ttgttctaag ttgggtgaag ttgaaagatt ataggcgata atttcgctgt taaagccatc
    25441 taaaactggt gataagtaaa gcttttgagt acttgctgga atggcaaatt ctgtcacatc
    25501 tgtgtagcac ttttccattg ttttagagcc ttcaaattgg ccttgaatga gattctctgc
    25561 cttcttgcca acgtctcctt tatgagaaga atattttcgt ttctgtcgca ttttagcttg
    25621 taaattgagt acttttatca agccttgaac tcttttatga tttaccagat aaccacgatt
    25681 tcttagttct aaatgaaccc ggcgataagt ataatttccc ttgtgttcga taaaaatgga
    25741 ttgaatttca gctttaagct attggtcctt atctggttta tctagctgtt tcaagtgata
    25801 gtagtaggtc caacgagcta gtttaatggc ttctagaaga agatctaacg aaaactcagt
    25861 cattaattct tgaacaattt ctgtctttct tctttctctt tttcctcctt caatcggagt
    25921 tctcttaact tttttaggat ggcattctcc gctctcaggt actctccctc ttgttttctc
    25981 aacaatagta tacccgtttt tcctgtattg tgctagccag ttaagaagta tcgtacgact
    26041 tgggagaccg tattcaagag aaactctatc tttagtccag ccttcatgtc agactttatg
    26101 aatcatttct tgttttaaat caggagaata gtaacgattt tttccttttt tgacgaactc
    26161 tattccgtaa cgatcaatca atttaatcat gtacctaata ttagaattgt ttatcccaaa
    26221 tttatt
//
LOCUS       DAVLTT010000022        25546 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLTT010000022 DAVLTT010000000
VERSION     DAVLTT010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25546
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.022"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(223..585)
                     /locus_tag="VYN15_001055"
     CDS             complement(223..585)
                     /locus_tag="VYN15_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV1452390.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            599..673
                     /locus_tag="VYN15_001056"
                     /pseudo
     CDS             599..673
                     /locus_tag="VYN15_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(900..1058)
                     /locus_tag="VYN15_001057"
                     /pseudo
     CDS             complement(900..1058)
                     /locus_tag="VYN15_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1446..2135)
                     /gene="rplA"
                     /locus_tag="VYN15_001058"
     CDS             complement(1446..2135)
                     /gene="rplA"
                     /locus_tag="VYN15_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV1452391.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2343..2768)
                     /gene="rplK"
                     /locus_tag="VYN15_001059"
     CDS             complement(2343..2768)
                     /gene="rplK"
                     /locus_tag="VYN15_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV1452392.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            2900..3037
                     /locus_tag="VYN15_001060"
     CDS             2900..3037
                     /locus_tag="VYN15_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452393.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEVADKTDEVSSKHCFEVVNRTDVVS
                     R"
     gene            complement(3077..3793)
                     /locus_tag="VYN15_001061"
     CDS             complement(3077..3793)
                     /locus_tag="VYN15_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV1452394.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKTKNEDGETKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AESGLSLEEYYGFEGGDYVD"
     gene            complement(3796..4266)
                     /locus_tag="VYN15_001062"
     CDS             complement(3796..4266)
                     /locus_tag="VYN15_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1452395.1"
                     /translation="MCLICQRIDLIKKEENPYFVKELETGYLVVGDHQYFEGYSLFLA
                     KEHVSELHHLKKETRLRFLEEMSLVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            complement(4268..5305)
                     /locus_tag="VYN15_001063"
     CDS             complement(4268..5305)
                     /locus_tag="VYN15_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV1452396.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREIADYLVKTLEGFGYQPVRTSK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKMDRIGGFPWNMIEGENCTI
                     HVASTGEKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTSEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRIYKEEKIELPVTTHFAFSVFEE
                     VGHGANSNILAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSTLVD"
     gene            complement(5509..6834)
                     /gene="brnQ"
                     /locus_tag="VYN15_001064"
     CDS             complement(5509..6834)
                     /gene="brnQ"
                     /locus_tag="VYN15_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV1452397.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(7005..7097)
                     /locus_tag="VYN15_001065"
     CDS             complement(7005..7097)
                     /locus_tag="VYN15_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1452398.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(7140..7292)
                     /locus_tag="VYN15_001066"
     CDS             complement(7140..7292)
                     /locus_tag="VYN15_001066"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1452399.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(7452..8030)
                     /locus_tag="VYN15_001067"
     CDS             complement(7452..8030)
                     /locus_tag="VYN15_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV1452400.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(8084..9484)
                     /gene="pepV"
                     /locus_tag="VYN15_001068"
     CDS             complement(8084..9484)
                     /gene="pepV"
                     /locus_tag="VYN15_001068"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV1452401.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9497..10102)
                     /locus_tag="VYN15_001069"
     CDS             complement(9497..10102)
                     /locus_tag="VYN15_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV1452402.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            10273..11073
                     /locus_tag="VYN15_001070"
     CDS             10273..11073
                     /locus_tag="VYN15_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1452403.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGENIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11255..12088)
                     /locus_tag="VYN15_001071"
     CDS             complement(11255..12088)
                     /locus_tag="VYN15_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1452404.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLAILIEKHGYVEDVKNFFDF
                     L"
     gene            complement(12078..13922)
                     /gene="uvrC"
                     /locus_tag="VYN15_001072"
     CDS             complement(12078..13922)
                     /gene="uvrC"
                     /locus_tag="VYN15_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV1452405.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALPPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(13962..14663)
                     /locus_tag="VYN15_001073"
     CDS             complement(13962..14663)
                     /locus_tag="VYN15_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV1452406.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14742..15974)
                     /gene="murN"
                     /locus_tag="VYN15_001074"
     CDS             complement(14742..15974)
                     /gene="murN"
                     /locus_tag="VYN15_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV1452407.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEEKLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15979..17199)
                     /gene="murM"
                     /locus_tag="VYN15_001075"
     CDS             complement(15979..17199)
                     /gene="murM"
                     /locus_tag="VYN15_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV1452408.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17311..18090)
                     /locus_tag="VYN15_001076"
     CDS             complement(17311..18090)
                     /locus_tag="VYN15_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1452409.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQDFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(18159..19820)
                     /locus_tag="VYN15_001077"
     CDS             complement(18159..19820)
                     /locus_tag="VYN15_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1452410.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19995..22217)
                     /gene="recJ"
                     /locus_tag="VYN15_001078"
     CDS             complement(19995..22217)
                     /gene="recJ"
                     /locus_tag="VYN15_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV1452411.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIIK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSIPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22494..23253
                     /locus_tag="VYN15_001079"
                     /pseudo
     CDS             22494..23253
                     /locus_tag="VYN15_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            23293..24057
                     /locus_tag="VYN15_001080"
     CDS             23293..24057
                     /locus_tag="VYN15_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1452412.1"
                     /translation="MISLFGLVAAKPVQANTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLTFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            24070..24747
                     /locus_tag="VYN15_001081"
     CDS             24070..24747
                     /locus_tag="VYN15_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1452413.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24757..25416
                     /locus_tag="VYN15_001082"
     CDS             24757..25416
                     /locus_tag="VYN15_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1452414.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVPVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
BASE COUNT         7275 a         5912 c         4717 g         7642 t
ORIGIN      
        1 taaactaacc tcctcattat tagcaaggat tctactgatt ataacctaat tcttagacta
       61 cttcaagact aactgtccaa taataatcta cagataaatc atccactctt aataaaattt
      121 tattcaatcc atctactcat tcccaaaagg ttgctgtata atgcaagaca tttttcttac
      181 tgattttact tttccttacc ctcaatttag tgagctaata aattattctt cttcaaaagg
      241 ttgagattta tctagtaact ctaaaacatt aatggtaggt agcaacattg cttcactgct
      301 atcaattgcc gaaactattg aaacaataga acgtaaataa tgataaagaa tagcagtacc
      361 atttacgtat agaatatcgg tgatattttc atctatattt atttcaaaat atcctattac
      421 agttacagat atttttttca tggcatcttt gtcaactaaa gaaacactaa gttttacggc
      481 tccatgacta taatcatctg tatgaccaac cttaactatg ggatataata tatcgaaggt
      541 aaatgtgaac aaactgatta ggaaatttaa accaacttct aacaatctgt tatactcaat
      601 gaaaaccaaa gagcaaacta ggaaactagc ctcaggttgc tcaaaacact gttttgaggt
      661 tgtagatgga actgacgtag tcagctcaaa acactgtttt gaggttgtgg atagaactga
      721 cgaagtcagt aaccatacgc acggcaaggc gacgttgacg tggtttgaag agattttcga
      781 agagtattag aaagctcgat ggactattcc agattcattc cactagattt cgaaatcgag
      841 taggggataa tctctagccc ctctcacacc accgtacgtg ccgttcggca tacggcggtt
      901 caactaactg ttaacgcatg tcgttcaagg taataatcca aacacgaaac cagtccacgt
      961 ttttcaagga ctggttttga tatagcacgt ttaagtaccg acttctgagc tactaattga
     1021 tagtggtccc cccagccaga taccttatcc gctatatagg ccttattatc acgttcctgt
     1081 tcgtagagcc acgatttcgc tatctcttcc tctgacgatt cttatttcca gcgtcagact
     1141 taaaacggtc tatccccaga ccgttttaat ccgctacctc acgatagtca gacttgggaa
     1201 tcgctattgg gttcaccggt agcaggtgcc caccgaggac ttacacctca aatatataat
     1261 aaaataaaat aaaatgaaat aagaacagga cgaatcgatc aggacagtca aatcaatttc
     1321 taacaatgtt ttagaagtag atgtgtacta ttctagtttc aatctactat acaacatgcc
     1381 cgtcgtacat caaaaaaagt tgagacatag cgtcttcaac ttttttacat tactttaact
     1441 actgattaaa gtgagtttac gtcaactttg ataccaacac cttgagtagt tgtgatagtc
     1501 aagtttgtta cgtaagttcc tttagctgta gctggttttg ctttttggat tgtttcgttg
     1561 aaagctttaa agttttcaac caatttttca gcttcaaatg atactttacc gatgattgct
     1621 tgaacgttac ctgcacggtc agcacggtaa gtgattttac cacctttaga ctcttcaact
     1681 gctttagcaa catccattgt tacagtacca gttttagggt ttggcatcaa gttacgtggt
     1741 ccaaggacac gtccaagacg tccaacaaga gccatcatat caggtgtagc gataactacg
     1801 tcgaagtcca accaaccgtc gttgatttta gcaacaaggt catcttcacc aacaaagtct
     1861 gcaccagcag cttttgcttc ttcagctttt gcaccacgtg cgaaaacaag aacacgtgaa
     1921 gttttaccag taccgtttgg caataccatt gctccacgga tttgttggtc agctttttta
     1981 acgtcgatgt tcaagttgta agcaacttct acagttgcat caaattttgc aaagttagtt
     2041 tcttttgcaa gtgctacagc ttcttctaca ctgtatgctt ttgtgctgtc gattttctca
     2101 agagcagcac gaagttgttt gcttttttta gccattttct attctccttg taagtggttc
     2161 aatcgatttt catctcccac gtcacttctc gaaatgatga agtcttgcgg gttttcagtc
     2221 tactattttt ctcttcctac ggccttaagc tcccttgctg tacccaagta caagcctcag
     2281 tcacttgcct agtatgaaaa gcaactaata gactgctgtg agattttcta ctgtgttatt
     2341 gattagtcaa caacagtgaa tcccatagaa cgagcagtac cttcgatcat acgcattgca
     2401 gactctacgt ttgctgcgtt caaatctggc atcttagttt ctgcaatttc ttgtacttgt
     2461 gcacgagtaa ctgtagcaac tttagtttta ttaggtgtac ctgatccttt ttcaacacct
     2521 gcagcttttt tcaaaagaac agcagctggt ggtgttttcg taacgaaagt aaatgattta
     2581 tcttcgtaaa ctgagataac aactggaatg atcataccag cttggtcagc tgtacgagcg
     2641 ttgaactctt ttgtgaatcc catgatgttg ataccagctt gaccaagagc aggtccaacc
     2701 ggtggagctg gtgtagcttt accagcaggg atttgcaatt ttacaagttt ttcgactttt
     2761 ttagccattt ttaaatcctc ctttgtggtt ttggcggtaa ttagagattt ttacctccca
     2821 caagtatgtt tttcacatac ccatccatta tacactattt atctggaatt gcaagagaaa
     2881 agtttatttt ttgtactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggctg
     2941 ctcaaagtac agctttgagg ttgcagataa aactgacgaa gtcagctcaa aacactgttt
     3001 tgaggttgtg aatagaaccg acgtagtcag taggtaaggc gacgctgacg tggtttgaag
     3061 agattttcga agagtattaa tcgacgtagt ctccgccttc aaagccatag tattcttcca
     3121 aactgagacc actctcagca atttcttttg cttcttttcc gacataacgc aggtgccatt
     3181 cctcagccat atagcctgtt tctttttcct tacctttgag ataacggaca acaaagccat
     3241 aatcagctgc atggtccaaa agccattggg ctgctttttc ttctgttacc aaatcaccat
     3301 cagtcccaat cacatcaaag gccaagcctg tctggtgttc gctataacca ggtcgagcag
     3361 aataacggtc ggcagcttct ttcccatctt gattaacata atcttgatag agtttggtct
     3421 gagtttcata acttctaaaa ccactgtaat gatcgctaat ggggaaacct gcctcttgca
     3481 tggctttgat gagtttgacc aactctgcct tggctgttgg attttcccct ggattatagt
     3541 ctttagacaa tggatagtgt ttgttggcta cgatgatttc atcgtatttc ccttgaatgc
     3601 tgtagtaatc acctttattg accacttctg ctttcttctg ggcagctcct tgagacttac
     3661 taccgactgt tccatcagct ttggctgtct gttctgtctt agtttctcca tcttcatttt
     3721 ttgttttttc ttgtgaacaa gctgctagac tcaaggctag caaagctgtc aagactaggt
     3781 atcttttctt catttctact cctttatttc taatagttta tctacttctg acgataaacg
     3841 tttgactaat cttttaatct catccggttt tgcttggcag gtttctgctg tcatttcttc
     3901 aaagggaacc caccagactg gtccacgacc cttgagacca tgaccattca tatcacctgt
     3961 ccgtcgtgga aacagatgcc aatgaagatg agcatcgcca tttcctagca gttcgatatt
     4021 cattttctca gcagcaaagg ccttggcaac tgcctcttgg actaaactca tttcttctag
     4081 aaaacggagt cttgtctcct ttttcaaatg gtgcaattcg ctgacatgct ccttggctag
     4141 aaagagacta tagccttcaa aatactggtg gtctccaacc acaagatagc ctgtttccaa
     4201 ctctttgaca aagtaaggat tttcttcctt cttgatgagg tcaattctct gacaaataag
     4261 gcacatatta gtccaccaac gtgctcttaa gataagcatc gaccattcgt tctgttgcga
     4321 tcaccgagtc aatatgggta cgctcatagg aatggctaga ctctatacca gcaccgagaa
     4381 gggcgtgttt gacttctgcc cctgcagaca tagccgctga agcgtccgaa ccataaaatg
     4441 gatagatatc cagcttaaat ggaatatctt gctctttcgc caaagccacc aaatgttgac
     4501 ggaagtcata gtgataaggt ccagaagcat ccttgacaca gatagacact gtatattcgt
     4561 ctgtttgctg gtcatctccc atggctccca tatccacagc cagatattct actacctgag
     4621 caagaatgtt agagtttgca ccgtgtccca cttcttcaaa gactgaaaaa gcaaaatgag
     4681 ttgttacggg caattcaatc ttctcttcct tataaatgcg aaggagattg agcaaaatcg
     4741 ccgcactgac cttgtcatcc aaatggcgag acttgataaa acctgtctct gtcacgacag
     4801 ttcgtgggtc aaaactgata aaatcaccga cctcaatgcc aagagcacga gtttcttttt
     4861 cactagttac tttggcgtcc aaacgcactt ccatattgtc ttgcgtgcgt tctgcagttc
     4921 ctgcatcctt atagacatgg caagaagttt ggtggatgag gatggttcct gatacttttt
     4981 cacctgtgct agccacatga atggtacagt tttctccttc aatcatgttc caaggaaagc
     5041 caccgatacg gtccattttg agacggccgt ctggtttgac agcacggaca atagcaccaa
     5101 gcgtatctac atgggcagtc acatagcgat gttgctcatc attttgacct ttaatagtta
     5161 cattgacacc gcccttggat gtgcgaaccg gctggtaacc aaaaccttct agagtcttga
     5221 ctaaatagtc cgcaatctca cgagtaaagc ctgttggcga cgcaatggct gtcagttctt
     5281 tgatatattc tactgtttga ttcatttctt cacctctttt gctacctatt ataacacatt
     5341 tatcatcgga taaaaaaaga aaatcactcc tgtagacttg actacaaaag tgattttata
     5401 ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggctgtactt gagtacgaca
     5461 aggcgacgtt gacgcggttt gaatttgatt ttcgaagagt attagtgatt attccatttc
     5521 aaaaacatcg ctttcttgct tgtttggtag aaccaatgag agcaagattc caacaatggc
     5581 tggcaccaac catgggagag atgccttggc aaaaggaaga acgctaacaa gatttgcaag
     5641 aaactcaacc ttaaacgagc ttcctagtac gcttgcaatg gcaataactg taaccacagc
     5701 aattgtcaac tgcatacctg gttttgaaag ggcaacaaat ttgttgacaa tgacaatcat
     5761 aacgatagca atcgtgattg ggtacaagat aaccagtact ggaattgagt acttgataat
     5821 cgcatcaaga cccaaattgg caatagcaaa tccaatcaag gtaaaggctg tcgcataaac
     5881 cttgtagctg atttgtggga agcgctcatt aaagaactca gctgttgaca caatcaaacc
     5941 aacagtcgtt gtgaagcagg ttacggtaac catagctgca aggaagagtt gagctgttga
     6001 gccaaagatt tcttgagtgg cttgtgacaa gatgtaaaca cctggtgttc cacccttcat
     6061 cgcttcagct ggtactggga aatgatttcc aagaaaacct aaaccgatgt aaagagcgct
     6121 gaaggcaagg gcaacaacga taccaacaac ccaaatagtt gaaatgtatt ctttcttact
     6181 tgaaaatcca agttgtttca aggtttgaac tgcgattacg ctaaaggcca ctgaggcaag
     6241 ggcgtccaag gtattgtaac cttctaggaa acctgtacca aaggcagaag cttgataagc
     6301 agctgaagca gcttgaggac ttgttccacc atatttgata gctcccagaa cgaccaagat
     6361 aacaatcaaa attgcaaaga ctggcgttaa aacacgtcca atgcggtcta agatttttga
     6421 tggattaagc gaaatcaaat aggctgccgc aaaatacaga accgtaaata caatcaagcc
     6481 aagtccttta tttgcatccg acaaaagggg gctaatccct acttcgtaag ctgttgtagc
     6541 agtacgtggg gtagcaaaga atggaccgat tgacaagtaa agaactgaga ggtaaagagt
     6601 cgcaaaccaa ggcgctatct tcgttgaaat ctcgtagata tatcctttag gatttagcgt
     6661 tccaataata agggtcaaga cggcgatacc aacgcctgaa aagacaaaac ctgcgatggc
     6721 aggaagaaaa tgttctccag atagagcacc tagagaaggc ggaaaaatca agttccccgc
     6781 accaaaaaat attccaaaca ggagcaaacc tgttagggta ccttttttag ccataaaaat
     6841 ctccttcata tttataaaat actgacctag tataccacga ttaggagtct gaaaaaagca
     6901 tcacgaggca aatgttaaat gttttcaatt ttcttaaaaa taagaattat ctaaaaataa
     6961 aactctccta cccagtccac accaagtagg agaaatgcaa aattttaaag ttcttcaaag
     7021 gctaacatgc caccctggac attgataaca ttataacctt gttctaatag gaattggcaa
     7081 gcacgcgccg atctcattcc agatttgcaa ataatataat gcaagcgatc tttgtccaat
     7141 taatcataac tatcagccaa ttgactaagc ggtaggttgt gggcaccttc taaatgaaga
     7201 gctgcaaact catccacttc tctcacatcc actaaagaaa gctggtcgtt ttggtaaagc
     7261 tggtaaaatg cgtcaaaggc tatttctttc attctttttc ttctaatact cttcgaaaat
     7321 ctcttcaaac cacgtcagcg tcgccttacc gtgcgtatgt taccgacttc gtcagtttta
     7381 tctgcaactt caaagctgta ctttgagcag cctacgacta gcttcctagt ttgctctttg
     7441 attttcattg actataaaat ggttttaatt ctttttttca aatctggcac tacttctgcc
     7501 tcaaaccaag gatttttggc catccagatt tgatttcgtg gtgatgggtg aactagcgga
     7561 aaataggctg gcagatagtc tttatagtgt ttcaccctct ccgttacctt cccactgatt
     7621 ttctcctgta aatagtaggc ttgggcatat tgcccaatca agagggttaa ctgaatatca
     7681 ggcaattcct gtaagagctg cggatgccat ttttctgcaa aacctgtacg aggcggaaga
     7741 tcacccgact tgccatgtcc tggaaagtag aaatccatag gcaaaacagc aaaataacct
     7801 gaattgtaaa aggtatcttc atccacacct agccagtccc gcaagcggtc accactttta
     7861 tctttccagt aaaggcctgc ttcttgagtt ttaagtcccg gagcctgacc gatgatattg
     7921 atgcgagcag tttttggcgc tgcaaagaga ggctcaatgc cacgctctgt atagctggca
     7981 ttctgcgaat ccgccatgat agcctgtttg attctttcga tttgagacat ctactttccc
     8041 tccaaaaaga agtccaagca taagatctca gacttctatc gttttatttg atcaattcgt
     8101 aaatagcttc ggcataaatt gctgctgctc ggaagagatc gtccaaggca ataaattcat
     8161 tggcttggtg catggtatca attgagtctg ggaacatagc accataggca actccgcgct
     8221 ctaacaagcg accaaaggtt ccaccaccga tgacttgttc atgaccttgt aggcctgttt
     8281 gtttttcata gacattcaac aaggtttgca caagtggatc ttccattggc acatagtgag
     8341 gggtatgacc atgttctgat agactgacag aagcaactgg caagttttct aggattgatt
     8401 tgatttgttc tggacttgtt ccttttggat agcggatgtt aagggcaatg gtattatcag
     8461 cacttgtttc atcgaagcgg aagactccgg cattcataga aagagcaccc atcttttcat
     8521 ccacatgagc aatcttgaga ttttcaccct catgatcgtt caagagaatt ttacctgcga
     8581 tgtcaaggta gtctttggct ggaccagcaa agccaaactg gctgaggaag agggcaaggt
     8641 aagttgcgcc attgacacct gaagcaggca tagcaccgtg ggctgattta ccaatgatcg
     8701 tcaccttgta tttgccagct tcttcttgga gttctcctct aagtttgtgt tctgcaacaa
     8761 aggcatctag tttagcttgc aagtcagcca aatcacctga aacgactgct gttgctgatt
     8821 ctggtaccat attttcacgt aaaccacctg taaagctgtg aagacgggca gcacctgtat
     8881 tttctcctgc aaagtggagg tattccgtga tatttccttt ttcaccattg atgattggaa
     8941 attcagcatc tggtgagaaa ccgaaatctg gtttggcaag tcctacgtgc tcaaagtagt
     9001 agtccatgtc tgcccagcct gattcttcgt ctgttccaac gatgaagcga actttcttag
     9061 aagttggaag acccaattct ttgatgattt tcaaaccata gtaacaagct gttgtaggac
     9121 ccttatcgtc cgaagccccg cgcgcataaa ggcgaccatc tttgatagtt ggtgtgtaag
     9181 gatctgtatc ccaaccgcta ccagctggaa ccacgtccat atgggcaaag attccgagaa
     9241 cttcttctcc atcaccaaac tcaaaatgtc ctgcgtagtt atcgacattc ttagttggat
     9301 aaccatcacg gtctgcgatt tcaaggaatt tttccaaggc ttttactgga ccaggtccaa
     9361 atggatgttg ggcatcagcc ttgctatcat cacgttctga gttgatttcc aaaaggctaa
     9421 acaagtcagc caagaggtct tctttgcgtt tttctacttc tgctgtaaaa tcaattgcta
     9481 tcattttttc ttcttcctat cttttttcga tgatttcatc tactggcaag cggtagcttg
     9541 gttccaattt gtcgtctgtg taacccactg tgatcaagag ttctgggcgg aaacggtctt
     9601 caatttccaa aacctcattg acttttgatt tgtcaaaacc aaggataata ttggaaccaa
     9661 ttccttggtc tgtaagagcg agaaccaagt tcatagcaac caaacctgca ttgagtgcta
     9721 ggtagtcgct gacttgttgt tcattgtagc gtgcaaattc agctggcaaa tttttcatga
     9781 agtattgaag ttgttcttct gagaaattgt tagcaccacc aactcgggca atcttacgag
     9841 cgcgtttggc aaggtctgta tctgtaaata gggcaatggt tacaggtgct gatgatacct
     9901 gctcaaagtt tgaaccataa gccaactttg ccagttcagc atttttctca cgaacaacta
     9961 caaatttcca aggctggctg ttgtgggcgc ttggcgccaa ggttgcaatt tcgatagccg
    10021 tacgcacatc ttttggatca acaggcttat cagtgaaatg cttggtcgca tgacgttttt
    10081 tatttaattc aagaaatttc ataatcgatt tccttttcta attctactgc ttccattcta
    10141 ccataatttg aaagagcttg cagggatttt tcatgattaa gtttttctat cacagacata
    10201 aaagatatat attggtttat caggaaagtt tctgataaac tagcaagtac tttacatttg
    10261 aatggagaca gtatgaaaaa atttagccta ttactagcta tcctaccatt tttggttgcc
    10321 tgtgggaatc aagctacacc caaagagact agcgctcaaa agacaatcgt ccttgctaca
    10381 gctggcgacg tgccaccatt tgactacgaa gataaaggca atctgacagg cttcgatatc
    10441 gaagttctaa aggcagtaga tgaaaaactc agcgactacg agattcaatt tcaaagaacc
    10501 gcctgggaaa gtatcttccc aggacttgat tctggtcact atcaggctgc ggccaataat
    10561 ttgagttaca caaaagagcg tgctgaaaaa tacctttact cgcttccgat ttccaacaat
    10621 cccctcgtcc ttgtcagcaa caagaaaaat cctttgactt ctcttgacca gatcgctggt
    10681 aaaacaacac aagaggatac cggaacttct aacgctcaat tcatcaataa ctggaatcag
    10741 aaacacactg ataatcccgc tacaattgat ttttctggtg agaatattgg taaacgaatc
    10801 ctagaccttg ctaacggaga gtttgatttc ctagtttttg acaaggtatc cgttcaaaag
    10861 attatcaagg accgtggttt agacctctca gtcgttgatt taccttctgc agatagcccc
    10921 agcaattata tcattttctc aagcgaccaa aaagagttta aagagaaatt tgataaagcg
    10981 ctcaaagaac tctatcaaga cggaaccctc gaaaaactca gcaataccta tctaggtggt
    11041 tcttacctcc cagatcaatc tcagttacaa taatactctt cgaaaatctc ttcaaaccac
    11101 gtcagcttta tctgcaacct caaagctgtg ctttgagcaa cctacggcta gcttcctagt
    11161 ttgctctttg attttcattg agtataagat atactaaaag cgattggacc agccaatcgc
    11221 ttttttagtt tgcattggct attttaggaa actcttacaa aaaatcaaaa aaattcttca
    11281 catcctctac atacccatgc ttttctatta agatggctaa aagttccaga ttgtgcccct
    11341 gatagttatc gtcacgacgc agttcttcat acatttcaat aaagggaagc cccttggact
    11401 tggccaattc taactcagcc tcgtaatcat aagcaacttt acgaaattgg atattgacca
    11461 attccccatc ttcaacttct atcacggcat actgggcacg gtgatttttt aacgcctccc
    11521 aattaaaata gggcatgcca atcgaccctg gattgatgat ttgttgccct tgacttccat
    11581 aacgaagcaa ctgcttgtga acatgaccat aaactgccac gtccgtttcc gcatctagca
    11641 gttggtcaaa tttctctgta tcattctcaa ctagcaagtc accaccatag ttcttatttg
    11701 gcaaattatg agagatagaa aagcgcaatc cgtcaatttc tttcttttcc agcaaaggca
    11761 agcttcgtag ccagacaatc gttgcaggat ccattcgctc catcaaaaac tgggtcatac
    11821 gcaagagctg aacttcctgt gggtcttcta agccatattg cccatctaaa gcctcaagga
    11881 cacgatcatc ccaattgcct cgaacacttg ctgtgatagg aaggtccttt agcagggcga
    11941 ctaagtcatt tgcgcctgga ccaggaagaa aaatatctcc cagaagccaa tattcactgg
    12001 ccccttgatt tttagcatct gcaatcactg cttctagcgc cgtcgcattg ccatgaacat
    12061 ctgataaaat tgcgatttta tggttcattg tggtttcctt ccgtttggta atctactctt
    12121 tcttctgcta cttgaggcaa ggcttctccc tgcgggttca actttctttg cacagcctct
    12181 gcaacgactc taggtacccc aacttcgaca atctcatcca cactggcttc cttgattttg
    12241 gtcaaagact tgaaatgctt cataagattc tgcttgcgtt taggtcccag accgtcaatc
    12301 ccatccaatt gagatgagaa agaatttttg gagcgcagtt ggcggtggaa ggtaatggca
    12361 aagcggtgca cctcatcttg gatgcgttgg aggaggaaaa attcctgaga attgcgagac
    12421 aagtccacca cctcaagcgg atctccaaag agcaattcat gggtttggtg cttatcattc
    12481 ttttgcagcc cagcaattgg aatatccaag cccagttcct cttggataac ctgcttagcg
    12541 atattgactt gaccttgccc cccatcaatc acaatcaaat ctggaggagg caaagcctca
    12601 cgctgtactc gaccatagcg tctgcgaatg acctctctca tgctggcata gtcgtctggt
    12661 ccaacaaccg tttttatctt gtacttacgg taatccttct tactcggttt accgttgaca
    12721 aagaccacca tagccgaaac agggctagtt cccatgatat tagagttatc gaaggactcg
    12781 atacgtactg gggtcgggat ttggagcaaa cgtcctagat tttcaatagc tccttgggtc
    12841 ttctcgacag atttctctag caggttaaat ttctgctcca gactaacacg tgcatttttt
    12901 atggctagat tgaccagctg ttttttctct ccacgttggg gtttgagaat cttggtatcc
    12961 accaaagcct tgacagcctc ttcgtcaata tcctgcggaa tcagtacctc attgggaact
    13021 aggtgagatt tttcttgata gaattgtcct acataggtca aaaaatcctc atctggatca
    13081 ttgaagtagg ggaagagatt gacatcgcgc tcgatgagct taccctgacg gacaaagaaa
    13141 acctgcacac acatccagcc cttatccaca tagtagccaa agacatcgcg attttggaga
    13201 tccttagcca tgacccgttg cttggttcga agcgttccaa tagcctgaat caggtcacgg
    13261 tattccgccg cacgttcaaa ctccatagtc tgggctgccg ctgccatttt gccctttagc
    13321 tcatcaatga ttttgttatc ctgccctttc agaaaatcag aaacctcctg ggccatagac
    13381 ttgaaataag tctcatcctt cttacagatg gtgtgggcca tgcattgacc gatatggtaa
    13441 taaaaacaga ccttagaggg cgggttggta cacttacgaa aagggaatat ccgatccagc
    13501 aaccgcttga tttcattggc tgcccccaca tcgggatagg gtccaaaata aagacctccg
    13561 tcctttttga cctgacgagt gataatcaag cgtggatagc gctcattggt gattttgatg
    13621 aaaggatagg acttgtcatc cttgagcatg atattgtact tgggcttgtt ttccttgatc
    13681 aggttgattt ctaggagaag tgcctcaata ttagactccg taacaataaa ttcaaaatcc
    13741 acaatttcag acaccagagc ctctgtcttg gtatcatgac ttccacgaaa ataggaccgt
    13801 actcgattac gcagattttt agcctttcct acatagataa tggtgccatt tttatcctta
    13861 tgaatgtagc aaccagggct ggtcggcaag agctctagtt ttgatttaat caagttgttc
    13921 atagttccat tatagcaaaa aaagtaggga aagatagtac cctactcact agtctcatat
    13981 atttttcgga ggtttgcaac atcctcttcc tggataccat aaaaggaacc tgctggttgc
    14041 atgacagact tctcatctgt atggtccaag ccaatcgcat gacctaactc atgttctgcc
    14101 gtatggacaa ggcgttcata ggagtagcca tagtatggat tggacaaata ataatgattc
    14161 aaccgcaccg ttacggacaa gaattgccct gttaagagat tagtttgact ttccgcctct
    14221 cctgccacag gagtgcctcc gtcgttcatc tccgtagccg taatatccgc cttactagac
    14281 tcagtcacga gttcaaagtt aaaagcaccc gtttgattcc agttctggat tgcttctaaa
    14341 taagcctctt gaaagcgtga atccatctgc ggatccaggt aaatacgagc agaggcctgt
    14401 gcccaccttc cttcagaatg ctggtgacta tctgtctggc ttaacttagg cagttgccct
    14461 gttttctccc attggtcaat actttgttga ccaattttta ctgaccgttc tgcttgcttt
    14521 agcgctcctt gaaaatcccc gttcagatac cagagaagtc cgaaagcaag cacacataag
    14581 agcacaacta tccaaaccag acgccaaaac aaacgccaca caaaagaaaa gaaagcccct
    14641 atcaaacgaa aaagccagcg catgtctctc cacctttcta gcaaataaga attattttac
    14701 taaaagaagc taaaagaaat ctaaatactg actttttcat cttaacgtcc tactattttt
    14761 ttgagtaact ggatagcttt gtattttaaa ggcgatggat ggtaacggaa agtacccgct
    14821 ttgcgtacaa tatagccatt aaaattctgt ttaaaacgca aaacaccatc acttccatca
    14881 aaaatccctt gaatgcctag gaagttgtat ttaggtattc cacgttttat gctttccaac
    14941 ataacatatt tttgaagcag tgcaggggca tagaacttat taaactcagt gtaggaacca
    15001 ctaaagagat aagtcgtttc ctgaggcata taaacaaata aactaccagc taaaacaata
    15061 tcttcttctc catatttttc aatcaagtct cgcgcttctg cttttcgaac ttcaaacgtt
    15121 tcaaattgac tagaatattc tctcagttga ttttgttttt tctcagaatg aggattttta
    15181 ctcaaatcaa gtcgcaactt gtccaatttt tcttctagtt tactttgttc accttgcaat
    15241 ttgctcatat actccgaaaa attcaagctt gctatgagaa actccgcttg ttctccaaaa
    15301 gtatcataaa aatgctcata atattctaaa cttttatcac tatattctct acgttcagag
    15361 gtttcttttg ttatattctt aaaaatcgat agttcttcac gttttaactt tttcaaccga
    15421 atgccaaagg tttcagcctt tttcaccaag ggtttaccct ttttgctaaa acttttaagc
    15481 aaactctttt cagttaattc agttaaatct ttatagtata accaatctgg ttctccacct
    15541 gggtaacctg ttgttaagcc atcaaattga taacctaaat cagtcaaacc ttgaataata
    15601 ctttttttct cagcatctat tggattacct tggctatcaa aagtttgata agtttcataa
    15661 ggttttacaa gcaactctaa tacaccattt tgcttggcat attcttttaa ctctgcataa
    15721 aaaactggaa gagcatcttg ttgggtataa atcggccccg aattgagttc catatgcaga
    15781 ccacccagca tgggcaagct ataaaccaga gctgcaactt gaatttctcc ttcttgtttc
    15841 aaagcaagat aaacaattcg agcccctctt ttttctagca aatcccccat ctggacagat
    15901 tgcataaagg aacgagaaga aacctgatca gaataagtct gaaactcttc tttcgtgagt
    15961 gttgttagtg ccatatactt actttctatg tttttttctt aatgttttac ggaaatcaag
    16021 agcaagtctt aacagaggat agagaggatg agtgggcatt gtaaattcac ccaagtattc
    16081 ttcaatcgtt ggattaaatt tttccttaaa atgataaagt ccaccattga gagagttttc
    16141 aacaccacct aaattttgcc agaccatacc tcgctcaaag gcatagcgag ccgtttcata
    16201 ccatgttaaa attggtgcat tgtaacgttt aaaatcatca tccataccag catatatatt
    16261 gacagaggta gtaccaaatt ccaaactcaa agtagccgct aaaggaactc tcgcttgacc
    16321 tacatctata tattcctgca agaaggtcaa ttcctctaac aaacgttctt tttccttctt
    16381 ctgcgcttct acttttgaag ttcgagtcga ctcagtaaag gtctcttcca aggctctatt
    16441 tttcgctaac tgttcttcta actcttgcga acgtttagaa acatccaaag tggccaaggt
    16501 gatataggcc ttgtccttaa aattatctaa caatttttta taataggctt cattcctcaa
    16561 atgaatctct tttcgcttct cagttttttt catcaactcc gaaaatgaat ctaatagttc
    16621 cagtccacca tattgaatct caagcccttt gtttcgtgct gttcgaatag cctgttttgt
    16681 tgacttggaa agtttatctt cttcaaaatt ttccttgtat attttcgcct gaatacgagg
    16741 ttgaatggtg tctcccattt cctccgtttt tcctgaccac cttactccca tttgttgcaa
    16801 actatcaata atagccagat tttcaggaaa ttctgtcttt tcctgattga ttaaactttg
    16861 agataggcaa atacttgggt caaaagtcac aaaaaccgct ctcttactgc gagcatagga
    16921 cttaatagac tgaatgacaa aattcaagag ttctttatcc ccataatcca atataggtcc
    16981 tcttgggatg taaaacattt tatagcctag cggaagagtt ctaatcaaaa tactagctgt
    17041 cgccagtaat ttttcttccc tgtaaacacc aaacttctca tgttgccaat tagacttaac
    17101 ttcctcccaa gcactacttt gtaatacatt ggctaattca tgttctttga caaactgatc
    17161 atattctaat gtgggaatgc caatttgata acggtacatt tcctactctc tttcctccag
    17221 tattttatta ctattctact actttcgttt gaaaagtcta gtgaaaacat attttatttt
    17281 agttctactc cccctatgct gaagttcaaa ctaagtcagt ctctcttcta atttgaaatc
    17341 aattggtaag gttgttaaaa aaacttccaa ttgtttttcc cagtagtacc actcgtgagt
    17401 tccagcacta tggctatagg tcacatcaaa acctagtttt ttgagatttt tcactgcgag
    17461 attattggct tcgtacaaga aatcctgttc gccacaccac gcccaaagtt tggtcttttt
    17521 atccgatttt ttagccagac tttcaagaga atagggacta gttgtccagt ctttaatctc
    17581 tccaaaaaca cctctccagt aggctggact tcccagattt tgactctcag gagaaaaatc
    17641 ttgaaagctc aatgcacctg aaaagctagc tgcatgagaa aaacgatttg tcgcaagagc
    17701 cagtttgaag cagccgtagc ctcccataga aagaccagcg ataaaggtct tttcacgctt
    17761 gctagtcata ttagggaaga agcgtttcag aacctgtggc aattcctctg ctagagccgt
    17821 gtagtagtca aaaccatact gggtatcggt gtaccaacca ttgctggtat tgggcataac
    17881 aacgatgaga ttagttcctc gaagcaagcg ttctacattg gtccgcttaa gccaactatt
    17941 atgatttcca gacatcccgt gcaaaaggta caagacggga atatcttcac actctggttc
    18001 ttccactcga ttggcatcag ggtagaggac attcaccccc cactccatat ccaatacttg
    18061 tgagtaatac tcgattttca ttactgccat gattttctcc ttctattttt ctataagaaa
    18121 aagccgaaac tcgactttct ctctgtttat ttcaacgatt attttgcttc catgactact
    18181 ggtaaaatag ctggacgacg cttggtttgg tcaaagagat acttggtcaa attatctcga
    18241 accttccctt taagatctgc ccagtcaaag tcatctcctt gaagatactc ttctaccgtt
    18301 tggttaatca attctgaact ttcacggaga atatcgcgac tcttcttgag ataaacaaat
    18361 ccgcgcgtat gaacacgagc cctagccaca attttcttct cacgacggtt gactgtaata
    18421 gccacgatga aaattccatc ctctgacaag accttacggt cacgaagaac aacatttcca
    18481 acatcaccaa tggcattccc atcaatcaag atatctcctg ctgaaaccga tccagctgga
    18541 acaaagtctc cattctcgta agccatggtc gtcccctttt taggaatgaa gatgcgttct
    18601 ggcaacatcc caactgccat ggcagcctta gcgtgagcat ccaactcacg atactcccct
    18661 tggacaggga agaggtactt aggttgcaaa agattgatca tcagctgcaa atcacgcaca
    18721 tttccgtgcc ctgatacatg taaactttgg gtaatcaatt tgacaacccc acctgcctga
    18781 taaatcatat tttccacacg cgcaacaaag gcttctttag caatagacgg agccgtagca
    18841 atatagacta ggtccccatc cttgatttct acataacgat ggcgaccaat cgacatctta
    18901 cgaagtccat tgataggctc acccatacga cctgtctcaa gaataatcaa ctcatggtct
    18961 tcaaagcgag acatatcttt aggcttaatc aaaagaattt cgttggctaa agacaacttc
    19021 ttaagacgaa tcgctgtgcg gacgatattt tcaatatcaa atcctgtcaa gacgatacgt
    19081 cgacctgttt tatccgcagc gtcaaaaatc tgctgaatac gagaaagatt actggaaaca
    19141 gctgcaacga tgatacgacc ttcccagtca gcaatagttt gggtaatttc atccctaact
    19201 tcactttcac tagccacctg aatattgctg tctgcattgg ccgaatcact gaggagagcc
    19261 aggacgccgt cacgaccaat ctctgccaaa cgagcaaaat cagttgcata agattcacta
    19321 gccgtttggt caaatttgaa gtcacctgta taaacgatgc ttccttccga tgtcttcaag
    19381 acaattccca gactctctgg aacggagtaa gtcgtaggga agaaggaaac cactgtccca
    19441 ccaaaatcaa tctccgtatt ctcatcaatg acatggaaat cattaaattt cttaacggca
    19501 tcatttcctt tgacaaagag ctttgccaac tcaatggtca actcagaccc aaatacagga
    19561 actttagcct ctgccaagag atacggtaga gcaccaatgg catccgcatg cccgtgggtc
    19621 aagaaaaccc cagcaatacg gtcgctattt tcaaaaaggt aatccatgtt tggaatcacc
    19681 acatcgaccc ctaattgttc attttcagga tattttaacc ctacattcaa aacaaaaatg
    19741 gactctccaa tttcagcaat gtacatattt tttccattct cacgcacacc accaagtgtt
    19801 gttaaactga tattactcat ttttcctcca aaatcttagt ttatcttgat tatagggcaa
    19861 ttctaccctc ttattctaaa agttctgata ctttcagccg aatcttttcc taccattata
    19921 ccattttttt gatgattttc aaaatgaagg tctgttttca aaaaagagtt gatttcccaa
    19981 ctctttccta acttctactc tttttccatc aaaaaatcat aaatttcttg caccgtaccc
    20041 agcgccatca tttcttggtc tttaacggtt tgtttgagat tttggtaaat ttgactttct
    20101 cctatctccc gctttggcgc ctctttattg actgtcatca caccatcttt tatcgtcaca
    20161 aagcctagtt cttcaaatac ttgaatcatc ttgaccagca agatttgttg aatattaaga
    20221 tatgcagcca aatctttcag cttgtagcga atatcaaact ctgggaactg gtaaatagtc
    20281 ttgtacaatt tggcaaactg atctctagtc ccataacctg tcagataata agccttgtca
    20341 atatcatttt tgaaatagac agcagagaaa tgctgttcct gaaaaatggt cttcagctga
    20401 gtaatatcct ctggaatgtt ttttacgaca acagcttcac tagccgcaag atttggcagt
    20461 tctccaggaa aatccaagac tggaacacct tctggcaaga ctgcattttt tccacgaatg
    20521 ttaaaaagtt gaacaccttc cactcgcgca tccaccatca tcaactggag ggcagtttgg
    20581 ccattccatt ggttgacaga caatttaacc gctaactcta gattcttggt ttgagaaaac
    20641 tctgtcgccc atctgccttg accaaaggct accacttcaa aactcgcctc acccttggaa
    20701 attttcagct ttagatgggc attacctgcc cccatagtac gagcactttc gacctgaaaa
    20761 ttcttgatat aaaaaatagg tttctgatta tccattccaa aaggagctaa acgttcaaaa
    20821 cttttgaccg tttccaagct aagtgcctcc aaatccaact cttcatctag gtttaactta
    20881 ttcttgccac cagcatctgc acctttttca cgaacataat cttccaaaac ctgagataaa
    20941 tctgagagtt gctcaacttc cagcgtcata cccgctgcac ctgcatgacc tccaaaggcg
    21001 atgaagaggt ctcgatgggg atccagagct tcaaaaatat cgaccgcttc cacactacga
    21061 gcactgccct tggcacgacc gtcttctata ttaagaacaa tgactgtctg tcccaattct
    21121 tccaataaac gaccagccac gattcctaga accccaggat tccagccttc cttggccaag
    21181 acctgaacct tcttctcagg atccaccatg gtcttggctt cttcatagat agactgaacg
    21241 atttccttgc gctcttcgtt tttctggtga atcataaggg caatctcatg cgcttcctca
    21301 tcatcaaatc cagtcaacaa atcaatggca ggattgggat catccaagcg acccaaggca
    21361 ttcaaacgag gagcaatctg gaaaccaacc gtttcttctg ttacttcgtt ggcagcaatc
    21421 ccagccatgt ccagcatttc ttgcagacca atgcgctggg tatgacccaa catttccaga
    21481 ccatattgaa ctaagatacg attttcatcc gtcagactca ccatatctgc aatagttcca
    21541 atagcgacca aatcaagcaa ttccacttgc acttcttcta acagggcaca agccaacttg
    21601 aaagcaactc cacaaccagc caaatattta aaaggataat ccgcatctgg atgttcagga
    21661 tggacaatag cataagcatc tggcagggtt tcaggtatgg aatgatggtc tgtcacaatg
    21721 acatctactc ccatagactg agccaatgca atagcctcat gaccagcaac cccattgtcc
    21781 accgtcacaa tcaaggaaat cccttcttgc tcgataaagt atttataaac actagcatta
    21841 gggccatagc catcggtaaa acgatttggc aggtaaactc ggcactcagc accaagttgt
    21901 tccaaacttt ccttaataat agaagctgaa gtcatgccat ccgcatcgta gtctccataa
    21961 acgagaatat tttccccttc ttcaatagcc tgacgaatcc gctccactgc cttgtccata
    22021 tcatggagca gataagcatc atgtaagtcc tccaaggaag gttctaaaaa cttcttcaga
    22081 ctttcttggt cctgaatccc tctctcaaac aataaccgag ctacctcagg acccagtcca
    22141 gccttcttgg ctatctttgt aaaatccgca tcttctacct gcagggcaaa ctgccattca
    22201 taagtaggtg ttatcaaaaa gacatccact ctttctaaga attctattgc ttcattataa
    22261 catgatttag acgttttctc tatccagatt gcttttttat aacattttat agtatattga
    22321 aactagaata gtacacctct acttctaaaa tattgttaga aatcgatttg attgtcccga
    22381 tcgatttttc ctgttcttat atcactatag tgaatttttt cagatatgat ttgacaagaa
    22441 cattctttta tcgtagaatc atgttataaa atataacaca agggagatct ctcatggctt
    22501 tagtagaatt taaaaacgtc gaaaaatatt acggagacta ccacgcactc cgcaacatca
    22561 atctccgttt tgaaaaaagg acaagttgtt gtcctgcttg gaccttctgg ctctgggaag
    22621 tccactctta tccgtacgat caatggttta gaggctgttg acaaaggaag tctcctagtc
    22681 aatgggcacc aagttgctgg tgccagccag aaagatttgg tacctcttcg caaggaagtc
    22741 ggcatggttt ttcaacattt taacctttat ccacacaaaa cggtgttaga aaacgtaaca
    22801 cttgcaccca ttgaagttct aggaattgat aaaaaagaag ctgaaaaaac cgcccaaaaa
    22861 tatctggaat ttgtaaatat gtgggacaag aaagattcct atcccgccat gctatctggt
    22921 ggacaaaaac agcggatcgc catcgctcgt ggtcttgcta tgcatccgga actcctcctc
    22981 tttgatgaac caacatctgc tcttgatcct gagactatcg gagatgttct agcagttatg
    23041 cagaaactgg cgcatgatgg gatgaacatg atcatcgtta cccacgaaat gggctttgct
    23101 cgagaggttg cggaccgcat tatctttatg gccgacggag aagttttagt agatatgaca
    23161 gatgtcgata gcttttttga caatccaagc gaacctcgtg cccaacaatt cctcagcaaa
    23221 attatcaacc acgaaagtga caaagtcaaa taaggaggcg cctatgaaaa aaaattcttt
    23281 ttatcagcat tattgattag ccttttcggc cttgttgctg ccaaaccagt ccaggctaat
    23341 actagtatcg cagacattca aaaaagaggc gaactggttg tcggcgtcaa acaagacgtt
    23401 cccaattttg gttacaaaga tcccaagacc ggtacttatt ctggtatcga aaccgacttg
    23461 gccaagatgg tagctgatga actcaaggtc aagattcgct atgtgccggt tacagcacaa
    23521 acccgcggcc cccttctaga caatgaacag gtcgatatgg atatcgcgac ctttaccatc
    23581 acggacgaac gcaaaaaact ctacaacttt accagtccct actacacaga cgcttctgga
    23641 tttttggtca ataaatctgc caaaatcaaa aagattgagg acctaaacgg caaaaccatc
    23701 ggagtcgccc aaggctccat cacccaacgc ctgattactg aactgggcaa aaagaaaggt
    23761 ctaaccttta aatttgtcga acttggttcc tacccagaat tgattacttc ccttcacgct
    23821 catcgtattg atgccttttc cgttgaccgc tctattctgt ctggctacac tagtaaacgc
    23881 acagaactac tagatgatag tttcaagcca tctgactacg gtattgttac caagaaatca
    23941 aatacagagc tcaacgacta tcttgataac ttggttacta aatggagcaa ggatggtagt
    24001 ttgcagaaac tttatgaccg ttacaagctc aaaccatcta gccatactgc agattaagga
    24061 ggacacccca tgacagattt atcatcttgg acagcctatt ttcaggattt tggacaattt
    24121 ttcaatggtt tcctctttac tcttgcccta gcgattggat cctttatcct cgccatggtc
    24181 ttaggaatct tctttggtgc catgtcaacc agtaaacgtc caattttacg cattttagct
    24241 cgcatctttg ttgaatttta ccaaaatact cccctcttgg tgcagtttgt tattgttttt
    24301 tatggcctac ctcttatcag tgaccatatc atcatgattc caatttattg gacagccgtt
    24361 ctctgcgtgg gactctatca cggcgcttat atcgctgagg ttattcgttc agggattcag
    24421 tctattccta gtggtcagat ggaggccgcc ttgtcgcaag gttttaccta tatcagtgcc
    24481 atgcgcttga ttaccttgcc tcaggccttc cgcatcattc tacctccatt gaccaaccaa
    24541 attgttaacc tcatcaagaa cacctctact gtagctatca tctctggagt agacttgatg
    24601 tttgtgacta agtcttggtc ggctctcaac ggaaactata tcccagcctt tttaggtgct
    24661 gctcttctct actttgccct atgcttccct gttgcccagt ttggtcgcaa gatggagcaa
    24721 gccaacaaaa aagcctattc actttaggag gttactatgg aatctatttt agaagtttta
    24781 accccagata acctagtctt tatctttaaa ggatttggct tgaccctcta tatttctctg
    24841 attgccatca tcctctctac tatcatcggt acggtgctag ctgtcatgag aaatggcaaa
    24901 aatcctatct tacgcattat ttccagtatt tatatcgagt ttgtgcgcaa cgttcccaac
    24961 cttctctgga tttttactat ctttttggtg ttcaaaatga agtccacacc agcaggtatt
    25021 acagccttta ctctctttac atcagcagcc ttggctgaga ttattcgagg cggtctcaat
    25081 gccgtagaca agggacaata cgaagcagga atgtcacaag gcttcacctc agcccaaatc
    25141 ctctactaca tcattctccc acaagccatc cgcaaaatgc taccagccat catttctcag
    25201 tttgttcccg tgattaagga taccagtctc ctctactctg ttatcgccct acaagaactc
    25261 tttggagcca gccaaattct catgggccgt tatttcgaac cagagcaggt cttcagtctt
    25321 tacatcctga ttgccctcat ctacttcagc tttaacctag caatttctag cctgtctcat
    25381 atgctagcca aacgttggca acaagctgca gaataatact cttcgaaaat ctcttcaaac
    25441 cacgtctgct tcaccttgcc gtatatatgt tactgacttc gtcagttcta tccacaacct
    25501 caaaacggtg ttttgagcag cctgcggcta gcttcctagt ttgctc
//
LOCUS       DAVLTT010000023        25408 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLTT010000023 DAVLTT010000000
VERSION     DAVLTT010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25408
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.023"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(442..1236)
                     /locus_tag="VYN15_001083"
     CDS             complement(442..1236)
                     /locus_tag="VYN15_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1452415.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHINS"
     gene            complement(1236..2243)
                     /locus_tag="VYN15_001084"
     CDS             complement(1236..2243)
                     /locus_tag="VYN15_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1452416.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(2243..3250)
                     /locus_tag="VYN15_001085"
     CDS             complement(2243..3250)
                     /locus_tag="VYN15_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1452417.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(3240..4265)
                     /locus_tag="VYN15_001086"
     CDS             complement(3240..4265)
                     /locus_tag="VYN15_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1452418.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNILG
                     NACKNAK"
     gene            complement(4658..4876)
                     /locus_tag="VYN15_001087"
     CDS             complement(4658..4876)
                     /locus_tag="VYN15_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1452419.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(5122..5400)
                     /locus_tag="VYN15_001088"
     CDS             complement(5122..5400)
                     /locus_tag="VYN15_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452420.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWYAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(5614..7245)
                     /gene="rlmD"
                     /locus_tag="VYN15_001089"
     CDS             complement(5614..7245)
                     /gene="rlmD"
                     /locus_tag="VYN15_001089"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1452421.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLDMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKISTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(7319..8293)
                     /locus_tag="VYN15_001090"
     CDS             complement(7319..8293)
                     /locus_tag="VYN15_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV1452422.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVENTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(8367..8981)
                     /gene="pmp23"
                     /locus_tag="VYN15_001091"
     CDS             complement(8367..8981)
                     /gene="pmp23"
                     /locus_tag="VYN15_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV1452423.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVQLNLYIIKCFTLFSTSG"
     gene            complement(8981..9955)
                     /locus_tag="VYN15_001092"
     CDS             complement(8981..9955)
                     /locus_tag="VYN15_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV1452424.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDVSRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(9963..11219)
                     /locus_tag="VYN15_001093"
     CDS             complement(9963..11219)
                     /locus_tag="VYN15_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV1452425.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFLLYED"
     gene            complement(11280..11711)
                     /locus_tag="VYN15_001094"
     CDS             complement(11280..11711)
                     /locus_tag="VYN15_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1452426.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKVQKRFIRIF"
     gene            complement(11713..12315)
                     /locus_tag="VYN15_001095"
     CDS             complement(11713..12315)
                     /locus_tag="VYN15_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV1452427.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(12299..13138)
                     /gene="prmC"
                     /locus_tag="VYN15_001096"
     CDS             complement(12299..13138)
                     /gene="prmC"
                     /locus_tag="VYN15_001096"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV1452428.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASNQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(13138..14217)
                     /gene="prfA"
                     /locus_tag="VYN15_001097"
     CDS             complement(13138..14217)
                     /gene="prfA"
                     /locus_tag="VYN15_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV1452429.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(14214..14804)
                     /locus_tag="VYN15_001098"
     CDS             complement(14214..14804)
                     /locus_tag="VYN15_001098"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV1452430.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            14928..15110
                     /locus_tag="VYN15_001099"
     CDS             14928..15110
                     /locus_tag="VYN15_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV1452431.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            15247..16620
                     /gene="mnmE"
                     /locus_tag="VYN15_001100"
     CDS             15247..16620
                     /gene="mnmE"
                     /locus_tag="VYN15_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV1452432.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     SQVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(16667..17602)
                     /gene="dapA"
                     /locus_tag="VYN15_001101"
     CDS             complement(16667..17602)
                     /gene="dapA"
                     /locus_tag="VYN15_001101"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV1452433.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(17658..18734)
                     /locus_tag="VYN15_001102"
     CDS             complement(17658..18734)
                     /locus_tag="VYN15_001102"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV1452434.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(19076..19148)
                     /locus_tag="VYN15_001103"
     tRNA            complement(19076..19148)
                     /locus_tag="VYN15_001103"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19113..19115),aa:Thr,seq:ggt)
     gene            complement(19248..19757)
                     /locus_tag="VYN15_001104"
     CDS             complement(19248..19757)
                     /locus_tag="VYN15_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV1452435.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(19755..19851)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            19880..20311
                     /locus_tag="VYN15_001105"
     CDS             19880..20311
                     /locus_tag="VYN15_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV1452436.1"
                     /translation="MKIPIQKFFNNEILAYLFFGIVTTLVAILLRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            20393..20770
                     /gene="mscL"
                     /locus_tag="VYN15_001106"
     CDS             20393..20770
                     /gene="mscL"
                     /locus_tag="VYN15_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV1452437.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(20812..21906)
                     /gene="hemH"
                     /locus_tag="VYN15_001107"
     CDS             complement(20812..21906)
                     /gene="hemH"
                     /locus_tag="VYN15_001107"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV1452438.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESQDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            22061..23284
                     /gene="pepT"
                     /locus_tag="VYN15_001108"
     CDS             22061..23284
                     /gene="pepT"
                     /locus_tag="VYN15_001108"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV1452439.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHIQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(23320..23949)
                     /locus_tag="VYN15_001109"
     CDS             complement(23320..23949)
                     /locus_tag="VYN15_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452440.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            23914..24135
                     /locus_tag="VYN15_001110"
     CDS             23914..24135
                     /locus_tag="VYN15_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452441.1"
                     /translation="MDLFQELICLVQKTFYFFLSICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNIL"
     gene            complement(24406..24754)
                     /locus_tag="VYN15_001111"
                     /pseudo
     CDS             complement(24406..24754)
                     /locus_tag="VYN15_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(24859..25408)
                     /locus_tag="VYN15_001112"
                     /pseudo
     CDS             complement(24859..25408)
                     /locus_tag="VYN15_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731455.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         7488 a         5110 c         4530 g         8280 t
ORIGIN      
        1 aaagtttagg gttgtctatt accttatctc tttcgatatc cttaaatttt tcataagcag
       61 tagataagtt atctaataaa tttcctatcc aaccctttaa tgtttttatc tcttctttta
      121 ttgtttttac aagttgatta tattttctta tttctctatt atagtttccc tattttcttg
      181 aataactttt tacttgaagt tttagctttt gaactagtcg ttgtactttc tttttgttta
      241 ttatcagtcc tgatcttttt aatattgctg ttattctcta tatcctattt ttcattcatg
      301 atattctttt actaatttta tcttaaattc tgtgctgtat ttgccattaa aaaactgacc
      361 tcctttagtt agttttttgg cctaactttt gagggtcagt tcaaaatttg cgacttttaa
      421 atgaattcca atattcaatt attaagagtt aatatggtgc ttgccaatag gaatcattag
      481 aggcgaattg gaaatagggt cacgtataat ttttgcttca agattaaaga tatctttaac
      541 tagtttatca tttagtatat cttcaggctt tccctctgca acaagtttac cttctttaat
      601 tgcaaatagg taatcagcgt atcttgctgt tagatttata tcgtgcaaaa tcatgcaaat
      661 ggttgtctta tatttttggt ttagatcagt caagaggtct aatagttcta tttgatatga
      721 gatatccaag taagtagttg gctcatctaa aagtaggata cttgtatctt gggctagggc
      781 tagagctatc catactcttt gcctttgacc cccagaaagt tcttcaacta ggttatttgc
      841 tagatcttca acattggcct taaccattga tctgtttatt atttcaaggt catcttttcc
      901 aagactctta aaaggctttc tgtaggggaa acgaccacgg cttacaagat cagctactgt
      961 tattgattca gggattattg gagattgagg taatatagct atgtgttttg ctaaatcttt
     1021 ttctttataa gaattaattg atttattatc aagcaatact tctccctcta atggctttat
     1081 aagtcgagac aaggttttaa tgagtgttga tttcccacaa ccatttgacc caataataac
     1141 tgatattttt tcttcaggta tttttatatt tatattttcc aagattattt tttcatcata
     1201 accgcaggta agattatttg accacagacc tttcattata tattcctcct gttcattttt
     1261 attagtaagt atattaagta tggtgaacct aacaagccag ttacaacacc tactggatat
     1321 ctagctggta aaatattttg agagaatatg tctgataaca aaactagtaa aattccaacc
     1381 aatccagcta atattgggct tcttttcttg ccaatattta aggctatggg accagctaaa
     1441 aaagatatac aagctattgg tcctgtaatt gaagtagaaa aagcagttaa agatacagcg
     1501 caaaaaatta aaacaagcct tgaaagctcg ggatttgctc caagtccgat tgctatttct
     1561 tcaccaagtt caataatttc tagtctttta ttaaaaaata aaactaatat agtagcaata
     1621 atacttacta ttagaacaag aggtatgtca tctaactttg taaaagataa agagccactg
     1681 agccatctca taacttcttg taattcatat cttgctactt tcaacaataa aaatgaggtg
     1741 cctgctcttg tgacagcttg aaaaccaata cctaatatta tcagtcttgc tgctgaaaaa
     1801 ccatcttttt tagctagtaa aaataatatt aaagatgatg ttagtccaca agttattgaa
     1861 ataattccag tagttaaact atttgttttt aataccaata tgcaaaagac cgctgcaata
     1921 gatgaagaac ttgtgacacc gattatatca ggacttgcaa gaggatttct taacatagtt
     1981 tgaaagataa atcctgccaa tccaaaagac cagccagcta taattcctgc taataatttt
     2041 ggtaatctaa tttccataat cgaaaaacta gctccaggaa cagtttcact atttaagact
     2101 ttaatcaaag ttgaaaaaga ataactttca tctccgataa gtaaaatgaa aaatgataga
     2161 ctgattatta ttaataaaaa tagtgaggaa aatagtgtta ttctattttt tcttttttga
     2221 atacctataa ttaaattttg cattagttat taacccctct atttttcata gttacataaa
     2281 taagtactgg acccccgatt attgcagtaa ttatccctac ttcaatttca cctggtttac
     2341 ctaacatacg gccgattata tcacatataa gcaagagctc tgcacctata aaagatgaag
     2401 aaatggtcat tgtgcgtata tctttgctta taaataagcc acaaaagtga ggaactataa
     2461 gacctacgaa gccaataggt ccaccaattg cagtaatact tgaacataaa agcacacttg
     2521 caattattgc aagtgatctt atcctattaa cattaactcc aagaccaaca gccatttcat
     2581 cacccatagc taaagcgttt aaatctgatg aaataaatat agctatcaag tgacctaaaa
     2641 ttataaaagg tagtagtgta gatatagaag ataatgtagc tgctccaagg ctacctattt
     2701 gccaaaatct aaatttgtct aagacgttat tattcggtaa aattaaaaaa cttacaaaac
     2761 tgcttaaagc catactaaca caagttcctg ataaggcaag ttttataggg gtaaggcctg
     2821 cttttccgct tacagcaatc gcgtatacaa aaattgcact tactaagcca ccaatgattg
     2881 caaaacttat atggcttatg cttgatgaaa ttcctaaaaa agaaagacca attactacac
     2941 taagacttgc tcctgtgttt ataccgagta tacctggatc agctattggg tttctagtaa
     3001 ctgattgcat caatacaccg cttatggcaa gactagaacc tgctaaaatt gcaaaaatag
     3061 ttctaggtat tcttttatat ataattgatt taataaaatc atcatttgta ttgcccattc
     3121 caaaagctgc taaaaaatct ctgatattaa tttcttttgt tccaagcttt aatgacaaaa
     3181 atattgtaat aagaagacct aggcagatta caaaaattat gcctaggttt atttgttttt
     3241 tatttcgcat ttttgcatgc atttcctaaa atatttaggt attcttcaat agtatagttt
     3301 attgaaagtg gtgttggagt gcatgaggct gctaacggtg tattatctgg aattacagca
     3361 acggcaccat ttttaattgc atttatttta cctaaaagag gatctttttg taaagcttca
     3421 agagttttat catcaccata agttatgatt acatcagcat catttatctt atttgcttct
     3481 tctgcagaaa tttcctttgc aaaactatct tcactctcaa attcttttaa tgattcaggg
     3541 aaaactagac ctaaatctgt taaataattt gctcttggat ctttgctagt ataaatccag
     3601 aattttgatg tatctgcagc attaatcata gtaaataata ctttttttcc tttgattttt
     3661 cctttgattt ctggatgttt ttctaattct ttggatatac gagcttcagt atttttgatt
     3721 aactcatcac cttctttttc catacctaag gcttttgaat caattttaat catatctctc
     3781 cataaagttt gccaaggttt agatttgtat gctgctacag gagcaatttt tgatagagtg
     3841 tcataatctt ctttagttat accagaataa cctgctaaga taacatctgg tttagaattt
     3901 gatattgctt caaagttaag tccatccaaa tcgtcaaata ggttagcttt accatttagt
     3961 tctttgattt tttcttctgt ccatggtaaa actcctttat cagcacttac accgtaattt
     4021 gcttttgaaa atccaacagg aactattcct aaagctaatg ctacatcatg atttccccaa
     4081 gcaatagttg caactctttc aggtttttta tctaatatag tttgaccgaa agcatgatct
     4141 aaaactattt tatcaggcgc atgctcttta gaagtatttt cttcattttt aacagaatta
     4201 gaagaacaag cgctaaaaac tatacacata gctaaaatag ctattagaaa aaatttgttt
     4261 ttcataaaaa ctccttaaac atatttcaag tctattgtat cgataataat tatcattgtc
     4321 aatagatgca gttacaaatt taataatata attttttcaa aaaaggatct agtttttatt
     4381 tttagttaaa ttatgtctat atttttcatt aactcatcaa taaaaatttg tttgctaata
     4441 tctctttctt ctgattttgt ttcaaggatt attgctacat cattcatatt tttaggtaaa
     4501 taccaaccat ctggcttatc tgaatatccc ttgaagccta attgattaaa agtagttatt
     4561 tgaccagtac cttgattgat gttttcttca acttcattaa agcctatact tctcttgcat
     4621 aatccctaac ttgatcttct gtccttaaag tcattttcta ttcctcgtca ctaaaattat
     4681 cttcaaaact aataatatca ttaggagtgc aagataaagc cttacatatt ctttctaaat
     4741 tcttaaatgt aattggttta tcctttccca tttgtgccat aacatttgtt gtaagtcctg
     4801 ccatagctat tacatctgtt ttctttagtc ctttttttgc taactgtatc cataatggtt
     4861 tatagttaag tgccataata tccctctttt tttcttcatt agatttattt aattatagca
     4921 taaatattga tttcattcaa tcttacattg atttagtgat ttgttttaga gaatttgttg
     4981 tgttattccg tccttatttt gccataaatt gttttaagtg ggacctctta tccttaccat
     5041 ttttacctcc taattttgag tataaaaaag acgatagagt ttttaatttc tatcgtctga
     5101 gatttacata ttaaattttc atcacaaaat aagactcttt aaagaatctt taaattcatt
     5161 ggtatgctgc ttacaatatc cattattaaa atggatattg taagcagcat accaactatt
     5221 tattttttga gttttaaact ttggtagaag tcttgaactc cttatattta cataactatt
     5281 tgcctctata actgttatga cacgaaacca acaagcaagt tcaagcacct ccatatcttt
     5341 attcaaatga ggactaagat attcacaaac tttatcataa acctctttat cttttttcat
     5401 aaaaggggca tacaacttag caaatttatc ctaaaatttt ttgttgcctt tatcaatcat
     5461 ttcaacgctc ctttaaatat aaaaatgatc ctatcaatct ttatattgag cctattttct
     5521 aattgatacc ttgcaagaaa ggaataatag ctgttcctat accaagtagg aatgtaataa
     5581 attcagaaag tcatatactg tcattctttt ctattaaatc attttgaagt gtctcaaagc
     5641 atccatgatg gcttcttctt tttcaggtgt acactgtgga ataatttgtt tatccttttt
     5701 agacttgttg taatgttctc gtaattctat tccacatttc ttttttatct gtgcaatata
     5761 taatgtcgaa atttttaatt caaatttatt ccaaacatat tctttgattt gagcatatgt
     5821 tgctttgctc tccgcacttg tcaaatccat ctcatccagc tcaatttcaa cacttatgtg
     5881 cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg acgtgatgcg tttgaggaaa
     5941 tagatccacc ggctggactt tcttcaattc atatcccaac tcttggtata gtttaatatc
     6001 acgcgccatg gttgcgacat tgcaggagat ataggcgatg cgatcggctc ctgtttgggc
     6061 gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga ggatcaacca agataacggt
     6121 tggttgaata ccttccttga gccatttctt catggcattt tcagccgtgt cacagacata
     6181 gtgggcatta gtaatcttgt tcaaagaagc attcttctgg ctattctcta ctgcttctgg
     6241 aatcagttca acaccgtaga cttctttgac atgcttggcg actgataaac caatggttcc
     6301 aataccagaa taggcatcaa taatcacatc atcttttttt aactctgcaa agtcaatggc
     6361 tgtttgatag agtttctccg ccatttcagt attgacttgg taaaaggctg ggccagcgat
     6421 ttggaagtca tttcccaaca tctggtccgt aatatagtct tgaccataaa gagtgcgcca
     6481 ctccttacca aaaatcgcat tggtattctg gtcgttgata ttttgcatga cagacacaat
     6541 ctctgggaac tgcttgataa cttgttcaat caattggtca acacgaaaaa cttttggacg
     6601 agttgtcacc aaaacgacca tgatttgtcc tgaatagtga ccacgacgca ccacaagatt
     6661 ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt aaatcaaaac gacggagcag
     6721 gtctcgaaga gctactacga cttggtcaat gacaggatcc tggataaaga aatcttcaag
     6781 gggcatgagg ttatgcgaat tcttacggaa aaatcctgtt tccaagacac cattcactcg
     6841 acgaacgggc acctgcgcct tattgcgata cttgactgga tgttccatat caagcgtttc
     6901 agcaacttct acatctgcaa ttccagcaat cttgtagaga ctgtccttga cttgcttggt
     6961 tttaaacttg agctgttctg gataagaaag gtgtcctaaa tccgcgattc ctgaacgcag
     7021 gtaagccaaa tctagatctt gattacggtg tggtgactgg acaaggtatt tttcaacttt
     7081 tccaaagcca atctttttat tgaccttgag gacacgcatg agaatttttt cactcggtaa
     7141 agcattctct acaaaaaaga ccaaaccatc taccttggca actcctgccc cttcatgggt
     7201 caaatcaaca atttcaactt ctacaatatc atttttcttt aacattcttt tctctttcta
     7261 ttggccgaca aaaaagacgg caacgttacg gttaccatcc attataccat gaaatttctt
     7321 aagaaccaaa actcttgaag aagttgacaa gggcttgcca gagggagctt aagaagttac
     7381 caccgtcctc tagcgcctta tccgcatcaa agttaaggtt gatattttta aaactgtcgc
     7441 cagcttgtga tacgatgctt tgtttaaggt catttagggt tttagtgaaa tctgcattgc
     7501 tgaggatatc actctttgag agattcaagg caaaattgat gatgatattg atctggtttc
     7561 ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatt ttcaacaatc ttgcgtacat
     7621 cttcttctgt cagatttccc ttgctttctt tagctttggc gagtcctgac ttgatatcag
     7681 ctagggcaac gtttaattta ttagcatcat agcctgattt gtccttgttt tcagcattga
     7741 tatctgacaa agcctttagc tcttcttgag ccaaatcttt attggcttgc ggcaccttgg
     7801 ctccattagc ttctagcgaa tagtagatcc cagccaaagc actctcacct gtaactggaa
     7861 taggggctgc tacagtgatt ttggcatgtt ccatacccag cgttactgct gcgtttcggt
     7921 acatatcctg agtcacctta gtgatatttt ctggtgtttc aatcttgacc tcaagtggcg
     7981 atttgtcacc tagcttttga atcttggctg atgaatacaa ctgtaagcta gagtcattgg
     8041 ccacattcat gattttagaa taaacatcag gtgtcatggt cttgagttct ttggtatctg
     8101 ttgaggcatt gtagcccagt tttttaagag tttgattttt ttggtcttca gatagggagg
     8161 aacctaggac atattcaggt tggacatagg tttcatcgat aactttttga acatctgttg
     8221 ctgcatggac gctattcata gctgttactg cccacaagac cgcagcacta gtcagaaaga
     8281 gtttctttct catagggaat ttcctccttt acctttctag agtaatatat ctatcttaaa
     8341 gaaaacttat aacaaaaaca cctgaactag ccagatgttg aaaagagagt gaaacatttg
     8401 atgatgtaaa ggttgagttg cacctgtcta gaataataat agtttcctcc atttacatag
     8461 agttcggcac cgtgaaaaat ggaaatggga tgaatataac tataagtctt tccagtcgta
     8521 ttaccaagca agggggcaac agtctcacga gagtactgtt tggctagagc caaggtattt
     8581 tccttgccat tttgggcgat aaaatcgata taggcaggtc caaaattata ggcttgaaca
     8641 gctgtccaga tatctacacc cttcttctgc gccagataga gattgcctgt cagagtttga
     8701 atgccttgcc gaatgctaga ggcattatca ttgatggtgt tggtggaacc acttgcagac
     8761 tcactagact gcataacatc gccttctttt ccttttgttt cagtataaat catagcaagc
     8821 acaagctctt cgtttgctgg ggtgtctttt tcactcaata tttctcgcac catgggttga
     8881 taggtcatga cttgtttgac atcttgatga acgcggtaag ctttatagcc agcaaaaagg
     8941 aagactgcta gtacaagcac tcttcgaatt cgtttaaaca ttatttactt tggatatcct
     9001 cgatattttt gattaagata gagtaggttc cattttcgtt ttggataaac tcaacagact
     9061 cggcgtcttg atagacgtta ttgggaacga tgagctcaat tccatttgat aaggagagtt
     9121 tttggttttc aaatttcttt aattggcgac tgacatcaat ttcatcaaat tgaacaggtt
     9181 ctggtacggc ttctttgact tggtcaataa agctcaaacg agccgtcaga ttgttgtcaa
     9241 aaaggtcatt agccaatttc tcaggtgaca attcattgct ttcttctagg ttgttgaaaa
     9301 tagctgattt gaccttggat tgaaattgaa aatcatctgt gttaaaagat tcagcaattc
     9361 tctgggctgt tttttccagt tccttgatag attttttagg agaaatctta ggagcgacag
     9421 caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt gtacttgatt cgtttttcaa
     9481 tcaggtgata cttgctactc tgaagattga ccaccaaggc ctcatcagct cctgttccaa
     9541 atccaggcag gttattctga gttagcttga ttggattatc aacttctcct ccgaggtggg
     9601 tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg ttctacacct tctttagaaa
     9661 attgaacaaa aatcaagtca ttggtcttga gattttcaga aatgctaaac tcctctttcc
     9721 agagattagc cagcgttact gatgtctcca acaaatcgtc tgtaatatga ttgaagaagg
     9781 gattttcttc ttcgaaaatc ccagtcttgg cttcatctga atacacatgt tcaatttttt
     9841 tacgcaggta ttcttcgatt tttggagtaa tattgagaaa cttatctgct aagaacagtt
     9901 cggtatcatc cggactgaac tggtgaataa tggctttctt aatataaatg tccataaaag
     9961 ttttagtcct cgtatagtag gaaggcatct gtcaattctt tgactgcact tctcacttct
    10021 tctaatacag cctcattttc tgaattctta agggttttaa tgatgagttc agccactttg
    10081 cgactttctt cttcaccaaa tccacgtgca gtaatggctg ctgctccgat acgaatccca
    10141 cttgtcttga atggtgacaa gctttcgtaa gggattgagt ttttatttaa ggtaatattg
    10201 acttcatcca acaagttttg agcaactttg ccgttttcta caactttagt cacatcaaca
    10261 aggaagagat ggttttcagt tccacctgaa ataatacgga aatcagggtc ttgcaagaag
    10321 acatctgcca tagccttgct gttcttaatt acattggcag catattcctt gaaggctgga
    10381 tccaaaactt ctttgaagga aactgcctta gccgccacaa catgctctaa aggaccgccc
    10441 tgaatacctg ggaaaatagc tgaattgatt tttttagcaa gttcttcgtc attggtcaaa
    10501 atcaaaccac cacgaggacc acgaagggtt ttgtgggtcg ttgttgttgt gatatgagcg
    10561 tatggaactg ggcttggatg aaggccagcc gcaaccaaac cagcgatatg ggccatgtcc
    10621 accatgagct tcgccccaac agcatctgca atttcacgga attttgaaaa atcgataatt
    10681 tgagaatagg ctgaagcacc agctacaatc agttttggtt ttacttcttg ggcttgtttc
    10741 aagatagcat caaagtctaa gagttccgtt tcaggatcca cactataaga aacaaagttg
    10801 taggtttgac cagagaagct aacaggagcc ccatgagtca aatgaccacc tgatgccaaa
    10861 tccattccca taaccgtatc acctggctca atcaaggaca tgtaagccgc acagttagct
    10921 tggcttcctg aatgtggttg gacattggca aatttagcac cgaaaatttc ttttgcgcgt
    10981 tcaatagcaa gagtctctac aacgtctact acatcagttc caccataata acggcgtcct
    11041 gggtaaccct cggcatattt gtttgtcaag atagaccctt gagctgccat aacagccttg
    11101 gaaactacgt tttccgaagc aatcaactcg atattatttt gttggcgttc ttcttcttta
    11161 gcaatagcat tccagagatc agcatcatat gctttaaaat catctttgtc aaaaatcata
    11221 ggtcttctcc tttattgtgt gactagtcca ttagtttgat tttacaataa gaaaataaac
    11281 taaaagatgc gaataaaccg tttctgcact ttatcacaag tataaccaac tttttcataa
    11341 aatgcatgag cacccagacg atgattggca gaatttaagc ggataaaccc ataaccacat
    11401 cttttggctt cttgttccaa cccttgtagt aaacttttac caataccttg accttgcgct
    11461 tgaggtgaaa ctgctaaagc taagatatta aatcctgctt tggaatagag tgattcgtaa
    11521 acttcagcgt ggacatatcc aagtaagaca tgattagctg catcctcata gccaagtagg
    11581 aaatgatggg aatcctgaga cagtctagct agttggctag ccgtttcctc tggactaaaa
    11641 gtataaccca aagcctcttg gttgatgtca catatcgctt tcacatctgt ttcttgcaaa
    11701 tctcttagca tttcaagcct cctcaaaaga aatctctggc aaccgagcaa gaatatcttc
    11761 tcgtttaatt gcgccttggc gtaagatttt caccttgtct ccagacaaat ccacaatagt
    11821 tgaatcctgt ccagttagaa aagcatcgtc ttccagaccc agaacctctt ggtcaaaatc
    11881 cttcagaatt tgttcaaagg ttacaccact tgcctgacct gagatattgg cagacggccc
    11941 aatcaaggga cctgtctctc gaattaaatc cagtgtgata gggtgactgg gcatccgaaa
    12001 tccaatagtt gcaaggtcag aatttaccca atagggaact cggtcattgg cttcgagaat
    12061 aatggtcaag ggacctggca aaaaggtctc tacaagtttt tgtagataag ctggctgatt
    12121 ctttgaaaag tgcaagatgt cctcgaaaga ggcgatattg agattgagtg ccttatctct
    12181 aggacgacgt ttgagttggt aaacatggtc aactgctttt tcatctaagg ccttggaaaa
    12241 aagaccataa acagtctctg taggtagaac gacagctcca ccattttcca actcttgtct
    12301 aatcctgtcc atcatcaacc acaaccatcc tattttgacc aaattggtcc ttgagtgttc
    12361 gaactctttt ttcaggaaga tgtttcctaa aaagttcggg aacactttga ccttgcttgt
    12421 atccaatttc aaggtaaatc ttaccaccat ctttgagata gtcttttgca tcttccgcaa
    12481 ttctacagta aatagctagg ccatcctcgt ctgcaaagag agctagatga ggctccgaat
    12541 gcaaaacatt caagcctacc tctgactcat cttcacgaga gatatagggt ggattggata
    12601 caattatatc atatttttca gaaatttctg caaaacaatc agatttttta aaaaatatat
    12661 taagattttg attgctagca ttctctgatg caagctctaa ggcctcttga gaaacatctg
    12721 ctgctgtcac tgaccaatct ggtctatttt ttgctagagc gagagcaata gctccactac
    12781 ctgttccaat atccagaact gagagattcg tctcaagatt ttcagttaga ataagctcca
    12841 ctaactcctc tgtttctgga cgaggaatca aaacccgttc atccaccttt aaatgcattc
    12901 cataaaaatc tgcctgtcca atgatgtact gagctggctt gtgagctgct agttgctggt
    12961 aaatatcttc tacaaattgt ttttcttcct ctgttgtcac ctcctgctgg agggcaaaaa
    13021 taaagtctgt aaaagataga tttttcagac tacgatagac aaaagagagg ctttccgctt
    13081 cctctccttg tcttatcaac tcttcttcaa aatttgaaaa taattgagct aatttcatta
    13141 tttgtttaat tcttctagtt tttgtgtttg gtcataaagc accaaggcat ccacaacttc
    13201 gtccaattta ccagacaaaa tcgtatctag tttttggagg gtcaagccga tacggtggtc
    13261 tgtgacacgg ttttgtggga agttataagt tcggatccgt tctgaacggt caccagtacc
    13321 gattgtcgac ttacgctcag cgtcttgttc atcctgagca atctgagcaa agtggtcagc
    13381 gacgcgtgca cggataatct tcatagcctt ctcgcggttc ttctgctggg tacgttcttc
    13441 ctgcatctca accttgatat tggttggcaa gtgaacgata cgaacggcag tcgcaacctt
    13501 attgacgttc tgtccaccag caccagaggc gtgatagatg tcgacacgaa ggtcttttgg
    13561 atcaatgtcg tattcaacct cttcaacttc tggcataaca agaactgtcg ctgtcgaagt
    13621 atgaacacgg ccttggcttt ctgtcacagg aacacgttgc acacggtggg cacctgattc
    13681 atacttaagc ttagagtata cagactgacc tgaaaccata gcaaccactt ctttaaaacc
    13741 accgacacca ttcatagagg cttccatgac ttcaaagcgc caaccttggg cttccgcata
    13801 cttttggtac atagttagca aatctccagc gaaaagtgcc gcttcgtctc caccagctgc
    13861 tccacggatt tcaaggatga tattcttgtc atcgtttgga tcctttggaa ggagcaaaat
    13921 tttcagtttt tcttcatatt cttctttttc agccttggca tctttgagtt cttgcttggc
    13981 catttcttcc aagtccgcat ctccgcctga ttccttaatc atctcttcgg catcgacgat
    14041 attttgaagg acttgtttat actcacggta ggctattacg gtgtcacgat tggaagcttc
    14101 ttcttttgaa agctccataa aacgcttggt gtctgaaacg acatcagggt cactcagcaa
    14161 ttctcctagt tcttcataac ggtcttctac agcttgtagt tgatcataga tgttcatttt
    14221 tcttcattct ccttattgat ttcaggggca aaataatgtt tacggcaaac cgagatatag
    14281 gtttcattac caccaatttg gatctgttct ccatcgtaaa cgggcagtcc atcctgtgtt
    14341 cgcaacacca tggtcgcctt tttcttgcaa tactgacaga tggtcttgat ttcgtcaatc
    14401 ttgtctgcta aaagcaagag atatttggaa ccttcgaaca attcattgcg aaagtcattt
    14461 ttcaagccaa aagccatgac gggtatgtct aactcgtcca caacacgagc taggtcataa
    14521 acatggtggc gtttgagaaa ctgggcttca tcgaccaaca cacagtaagg tttttctggt
    14581 aggcctcgga tatagccaaa gatatccgtt gtttcctcaa tcgcaagggc agggcgtttc
    14641 atgccaattc gactcgacac atagccaaca ccgtcacgcg tatccagagc tgaagtcata
    14701 atcacaacac cttttccttg ctcctcatag ttataggcca ccttgagaat ctcgattgtc
    14761 tttccagagt tcatggtccc ataacgatag tacaactgtg ccatgtttct tgcttcacgt
    14821 ccatttctaa atttttgcta cattctagta tatcataatt ttcttaagct ttaaacggca
    14881 aaatgtggta aaatagaaga aatcaaaaac tagtggagga agctattatg ccatttgtac
    14941 gcatcgattt atttgaagga cgcacgctcg agcaaaagaa agctcttgct aaggaagtaa
    15001 cggaagcggt tgttcgcaac actggagcac ctcaatctgc tgtccatgtc atcatcaacg
    15061 acatgccaga aggaacttac ttcccacaag gggaaatgcg taccaaataa gctagcttaa
    15121 gcagaattgc ttaggctttt tcaatctcca agtagcattc attgaagaaa tatcctaaat
    15181 ttgttacaat ttgaaaagaa acttggagaa tttccaagaa aatagctatt aattaaagga
    15241 aacattatga ttacacgtga atttgatacc atcgctgcta tctctactcc actaggtgaa
    15301 ggagctattg gtattgtccg cctgagcgga acagacagtt ttgctattgc gcaaaagatt
    15361 tttaaaggaa aagacttgag tcaggttgct agccacactc tcaactacgg tcacattatt
    15421 gatcctctga ctggtaaagt catggacgag gttatggttg gggctatgaa gtctccaaag
    15481 accttcactc gtgaggatat tatcgagatt aacacccacg gtggtattgc ggtgaccaat
    15541 gagattctcc agctagctat ccgtgaagga gctcggttgg cagaacctgg tgaatttacc
    15601 aaacgtgcct ttttaaacgg tcgcgtagat ttgacacagg ccgaggcggt gatggatatc
    15661 atccgagcca agacagacaa ggccatgaac atcgcggtca aacaacttga tggttccctt
    15721 tctgatctta tcaataatat ccgtcaagaa atccttaaca cacttgccca agttgaggtc
    15781 aatatcgact atcctgagta tgacgatgtt gaggaagcca ctactgctgt tgtccgagag
    15841 aagacaatgg agtttgagca attactaacc aaactcctta ggacagcacg tcgtggtaaa
    15901 atccttcgtg aaggaatttc aacggctatc attggacgtc ccaacgttgg gaaatcaagc
    15961 cttctcaaca acctcttgcg tgaggacaag gctatcgtaa cagatatcgc tgggacaaca
    16021 cgagatgtca tcgaagagta cgtcaacatc aatggtgtac ctctcaaatt gattgataca
    16081 gccggtattc gtgaaacaga tgacatagtg gaacaaatcg gtgttgagcg ttcgaaaaaa
    16141 gccctcaagg aagccgactt ggttctacta gtgctaaatg ccagtgaacc actgactgcg
    16201 caagacagac aacttcttga aattagccaa gataccaatc gcattattct acttaataaa
    16261 accgacctgc cagaaacgat tgaaacttcg aaactacctg aagacgttat ccgtatttca
    16321 gtccttaaaa accaaaacat cgacaagatt gaagagcgaa tcaacaacct cttctttgaa
    16381 aatgctggct tgattgagca agatgctact tacttgtcaa acgcccgtca catttccctg
    16441 attgaaaaag cagttgaaag cctacaagcc gttaatcaag gtcttgagct ggggatgcca
    16501 gttgatttgc ttcaagttga cttgactcgt acttgggaaa tcctcggaga aatcactggg
    16561 gatgctgctc cagatgaact catcacccaa ctctttagcc aattctgttt aggaaaataa
    16621 gaaaaatcca tgatccttca ttcggtcatg gattttattg tctttattag taatctggtc
    16681 ttaagacccc tgttacagtt gccttagttg cttcgtagtc gccatctacg acaaccttga
    16741 taatgcgttt ggcatcttct tctggtgctg gaacaagagg tagacgagtg ggtccagctt
    16801 caaatcccat atagttaaga attgccttaa ctggagcagg acttggataa gagaagagag
    16861 cattaacctt aggaatgaat ttacgctgaa ttgctgcggc tttcttcata tcgctttctg
    16921 caatggcagt aaacatctcg tgcatttcat ccccatttgt atgagaggca acagaaataa
    16981 ccccatccgc cccaaggttc atggcatgga aagcatctcc atcctcacct gtataaatca
    17041 agaactcttc aggcttgtgc tcaatcaagt aagccatatt agccaagcta gtacattctt
    17101 tgacaccgat aatatttgga tggtcagcca agcgaagcat ggtttctgga gtcaattcga
    17161 caactacacg ccctggaatg ttatagataa taattggtag gtcagaagca tctgcaatag
    17221 tcttaaagtg ctgatacatc ccttcttgag aaggtttgtt gtagtaagga acaatagcaa
    17281 gcccagctgc gaaaccacca aattccgcta cttctttgac aaactcaata gagtcacgcg
    17341 tatcattagt acctacaccc gcaatcaaag gaacgcgtcc attgacaacc ttttgtacag
    17401 ccgcaaacaa ctccaactcc tcatcgtggg tcaaagttgg actctcagca gtcgttcctg
    17461 cgagaagaat tccatccgta tgatgggcca ataaatgctc aatcaaggct ggaatagcat
    17521 caaagttaat agaaccatcc tcatgaaagg gggtaataaa ggctgtaatg attttacatt
    17581 cttttaaatc ttgataagac atgaaaacac ctctctattt caaagaagga gttcatctga
    17641 actcctaaac gatatgacta ttttaattca aatttcaatt cggctgttgg acgaaccaat
    17701 ccacgttcat gaagagtttc agcaatctga actgagttcc aagcagcacc tttgagaagg
    17761 ttatctgaaa caacccacat gtgaattcct ttttctgcat ccaagtcttt acggatacga
    17821 ccaacaaagg tatcacgcga accaactgca ttgatagctt gaggatagat ttgatgagct
    17881 acatcatctt caagaacagc acctgggaag gctgcgatag ctgcttttac ttcttcgatt
    17941 ggagccactt cttttgtttc gatataaaca gactcagagt gagctgacaa gactggaata
    18001 cgcacacatg ttgcagatac tgcaatgcta tcatcttcca taattttctt agtttccttg
    18061 gtcatcttca tctcttcgta cgtgtaatca ttatcagtga aaacatcaat ttgtggaaga
    18121 gcgttaaagg cgataggata atgtttcttg tcaccacctg aaggcaaaat ttccgcatgc
    18181 aaatcacatg gtttcacacc atcattcaag acttcacgaa gttcacgttg tgtctcaaga
    18241 attgctccca taccagcacc tgaaacggct tgataagttg aaacaatgat acggtccaag
    18301 ccccattttt ggcgaaccgg ctcaagagcc accatcattt ggattgttga acaattaggg
    18361 caggcaatga ttccgttgtg ggcatcaagt gcatgagcat tgacctctgg aacaaccaaa
    18421 ggaacatctg gattttgacg gaaataagat gtattatcca ctactaccac gccagctttt
    18481 actgcgtatg gtgcatactt agctgatgta gaactacctg ctgaaaagag agcaatatca
    18541 actccttcaa aagctgtttc agtcgtttct tcaattgtaa tatcttgatc tttaaatttc
    18601 aatgacttac ctgctgaacg tgcagaagca aggtaacgga ttttatcgat tggaagtgtt
    18661 gattcttcca acatttttat catctgagca ccgacagcac ctgtcgcgcc gactacagca
    18721 actgtatatc ccataaataa cctctttcgg aattttctaa aaatttctat aatagaagta
    18781 ttatactact ttttccatga attgcaaagc tttttcatca ttttttggaa aataaaaatc
    18841 ccagtcgcta gactagggac taagaggcat cttcatgtga tgagcaggtt cacacaactc
    18901 atcaaggtcc gctcctgcgt tatgacctcc ttatgctcaa tagtagtccg aagactacct
    18961 atcgactcat cgcatattct atattactag agatacttga ttttgtcaat aagaaatttt
    19021 ttcgatcgag tataacaaaa aactctcgta ttcaagagtt tccctataca tatcatgcta
    19081 attgccggga tcgaaccggc gacctcatcc ttaccatgga tgcgctctgc caactgagct
    19141 aaatcagctt acttaagaag tatactatat tcagaaaaac ttgtcaagtt tccttagaaa
    19201 ttttccatag gaaaaagcca ggtaagaact acctagctta tcttcttcta tttacttaaa
    19261 tcaattcgac gaccaatttt accaataata atcgccccaa taatcaatga agcaaattca
    19321 ccgattcctg ttgtaaacca agtaaggaag aatggtaatt ctgctacaat atttaactct
    19381 gcagcgatag taaacatgga aattgaaaag aggattgaaa agaagaaatg atcttttcga
    19441 atcaatccgt taaagaggta atccttgcta tattttgcaa aaagccaaac acctaaactg
    19501 aggaatacta aggttgaacc accaccaaca aagacatcta gcagtccgaa gctaaagaaa
    19561 ttagcaatca tacaaccgat ggtaactccg atgatgtact taggattgta aaaagccata
    19621 aagttcatca tttctgaaat acgaaactga taagcaccat agctgatggc atttaggggc
    19681 ggtgtgacag tcaaaacgac gtagatagca gcgacgattg caatatctgc aacatcacga
    19741 atagttaatt ttttcatctt ttctcctttg gcggttgccc gcgtgtaata tgcttggtga
    19801 aagaagctaa gcaccaaggg ttgctttatt caaccctact agtatagcac aatagcctgc
    19861 tttatgctat acttaacaca tgaaaattcc tattcaaaaa ttttttaaca atgaaatctt
    19921 agcctatctc ttttttggta tagtgactac tcttgttgct atactattac gattagtcat
    19981 ttatcagcta agtcatcaag aactccttgc tacggccttg gcaaatatta tcggtatttt
    20041 atttgccttt atcacaaatg atacaattgt atttaagcaa aaaaagaaaa atagacttat
    20101 ccgtttagtg aaattttctc ttgctcgcct ttctactttt ctgttagact tgtttttaac
    20161 ttttctcttt gtaacccaat ttcctcacat catagggcaa ttcgtaactg aaaacattga
    20221 taagataaat gctattgaaa caataattgc acaaatattc attattatca tcaattatat
    20281 cttgagcaag gtctatattt ttagaaaata atgctccatt tatgagcctt ttaattgcct
    20341 tctataatga tttaggatac aatgaaacac gaaacattga aaggaaaaca gtatgttaaa
    20401 aaatctaaaa tcgttcttgc ttcgaggaaa tgttattgac cttgctgtcg gtgttgtaat
    20461 tgcctctgct tttggtgcta tcgttacttc acttgtaaac gacattatca ctcctcttat
    20521 tttaaatccc gctttgaaag ctgctaaagt tgaacgtatc gctcaacttt cttggcatgg
    20581 agtcggctat ggtaacttct taagtgctat tatcaatttt atctttgtgg gtaccgccct
    20641 cttctttatt atcaagggca ttgaaaaagc acagaaactg actggcataa aggaagaaaa
    20701 aactgccgaa aaaaaaccaa ccgaattgga agtccttcaa gaaataaaag ctctccttga
    20761 gaaaaaataa tcgattaaaa ggatctagcg caaagctaaa tccttttttc tttactcttt
    20821 gggtaacttg cctgcttttt caagcatttt tttgataaga taaggcatct taacattctc
    20881 ccgccctttt ttctcaatca gttttttcac aaattctggc atttgtaaat cttgagattc
    20941 ggctaagata tttttagtct catctgaagg cactaactca tcaaaggttt cttcttctgg
    21001 gagaaattcc ttaaactctt gattttcatt gactctaact gtattgacca aggcatcaat
    21061 caaacgagaa tctgtatttg gcattggtgg acgatggtag tttaccccaa attcctgaca
    21121 taaatcataa cattccacat cattgtcaaa caagacctca atatgctcac tgatgaaact
    21181 aataggtaca aaaatataat ggtctggatg ttctgtctgt tctctgagat actccaaaac
    21241 atctggttta atccatggaa taccaatatc actctcactc tgccaagtgt tggtatattg
    21301 ttctgaactc aagcccagtt tttcagcgac tagcttgcta ttttcgaaaa tttggtctat
    21361 ataaggatct ccaaagtcca aggcaaaaat aggcacacta tgggctgaaa agatgacttt
    21421 aaagctgtct tgctttactt cttcttttaa aatcttagca atttcatctg cccaatagtt
    21481 taagagcgct tcttcctgat accagtcctt aatgaccaaa aattgaattt gtttgctttc
    21541 taaaaatttt tcatagccca tgacagagta gaaagaataa tggggctcca aaatcaagca
    21601 aatacactgt tcaattccgt ctgcttccat ttgaccgatc acatctggaa taaagggact
    21661 ggaaaactta ttagcaaagt agacactgta ttcattcccc agcctagctt ctaccaaggc
    21721 aacctcttga cgggtaattt tttgcagagg cgtgcctcca attcgtacat aattatcata
    21781 gagagtctga atctcgtggt cttggggtct catcccacga cgaatatttg tgaaaaaatc
    21841 agctacacct tcaaaggtaa tctcttctgg tgaaccgaag gtcatcatta aaattgcttt
    21901 tttcatgact gcttccttgt gatgttttta tcaagtttat tttatcatta attcatcgat
    21961 aagtaaacgc tagcataggg acattctcaa tcttctgtct tttgtttttc tcttctttct
    22021 atgatacaat ggaaaaaata aattcaaaag gagttttttt atgacttatc caaatctctt
    22081 ggaccgcttc ttaacctacg ttaaggtcaa cacgcgctct gatgaacact ctactactac
    22141 tccaagtaca cagagtcagg ttgacttcgc aacaaatgtc ctaattcctg aaatgaaacg
    22201 tgttggactg caaaatgttt actatctacc gaatggtttt gctattggaa ccttgccagc
    22261 caacgatccg tctttaacac gtaagattgg ttttatatcg cacatggata ctgctgattt
    22321 taatgctgaa ggagtcaatc cacaggtaat tgaaaactac gatggtggtg tgattgaact
    22381 agggaattct ggtttcaaac tcgatccagc tgacttcaag agtcttgaaa aatatccagg
    22441 acaaacgctc atcacaacag atggaacaac cttgctaggt gctgatgaca agtcaggaat
    22501 tgctgaaatt atgacagcca ttgaatatct aactgctcat cctgaaatta agcactgtga
    22561 gattcgtgtt ggttttggtc cagatgaaga aatcggtgtt ggtgccaata aatttgatgc
    22621 agaagatttt gatgtggatt ttgcctacac tgttgatggt ggtccactag gtgaacttca
    22681 gtacgagact ttctcagccg ctggtgctga attgcatttc caaggccgta atgtccaccc
    22741 tggtactgcc aaagggcaga tggtcaatgc ccttcagcta gcaattgatt ttcatattca
    22801 acttccagaa aatgaccgac ctgagttaac tgaaggttac caaggttttt accatctaat
    22861 ggatgtgaca ggtagtgttg aggaggcgcg tgcaagctac atcattcgtg attttgaaaa
    22921 agatgccttt gaagcgcgta aagcatccat gcaatctatc gctgataaga tgaatgaaga
    22981 acttgggagc gaccgtgtca ctctcaactt gacagaccag tactacaata tgaaagaagt
    23041 cattgaaaaa gatatgactc caattaccat tgctaaagcc gttatggaag atctaggtat
    23101 cacgcctatt atcgaaccaa tccggggtgg aacagacggc tctaagattt cctttatggg
    23161 aatcccaact ccgaatatct ttgcaggtgg cgaaaatatg cacggacgtt ttgaatacgt
    23221 tagccttcag actatggaac gtgcagttga taccatcatt ggcatcgtag cttataaagg
    23281 ctaaaaagac gaggtggctc agctacttcg cctttctttt tattctactg gtttttcttg
    23341 atttccagta gttgtagaag attctgttgt ttcattttct gaagttgatt cagcaggttt
    23401 agaatctctt gtattgcttg gtttgttttc gtcgctagca gtttcaatgt tagattctgc
    23461 agttgcgttt ggttggttct cagcactggt gttatcacta tttgcttcag catttcttgc
    23521 tggacttgtt tcttcacttg cgctagcttt tgactggatt tgatgattca aaactagaat
    23581 agcttttgtc gattcaagta aagctgtttt gtctttactc ttagcagaaa gttgatctaa
    23641 taatgcatcc accttatcaa agtccgcatc agatccatta ttactttcta aataagagtg
    23701 aagcgacatg agaatatcgt agagtttttg atagagtaca agtgtctgag aatcttgctc
    23761 agcattttcc ttttcttgtt gaagggcgct agcgatacga gtcaaaacat cttttacctg
    23821 actgtttact tcatccaagt ctgcatcagc cttgtttgtg gcagctttta gattttctac
    23881 ttcttctgcc aaggattgtc tgattccttc ttcatggatt tgttccaaga gttgatttgc
    23941 cttgttcaaa agactttcta cttcttcctt tctatctgtc gcagattatt ggttgctatc
    24001 taccatgtac tcctaaaaca ggagagttat aatccaagat tacaaggcct tacagaaata
    24061 agaaatccag ataagacaat gttcgtccaa gacgctattc gcttcgcaca gcagcacgga
    24121 ttcaatatac tttaatttta aagtttaggt gtcaagacct ctttttagtg tacccaaaat
    24181 ttagagaagt aatcaatcaa ctaactttta tttttttcaa actttcagta aactgaccta
    24241 aagctaactc aatctgtctt tgtagatgct tctgctatca gctagaagtt gatctacttt
    24301 tgccaagact gccttctcat caaaagttcc aggttgatag ttggattgca gggatggaat
    24361 cttgtttttc aaagccgctt catatccctt agtttgaacc ttgatgtagt gattgtggtc
    24421 gccatgagga atcacaaaac cttctgaatc ttcacttata attcgattgg catcaaaaac
    24481 catgaccatc ttcttcctca tggtggacat gtagtgacgg attacttaat acagaactag
    24541 aagaacttcc tacctcttcc gtgttagagt gtgatggggg attgttaaga gatgacttag
    24601 gaatatagtg atagtgttcc ccatgtctta ctatataagc atcacctata tctctgacaa
    24661 tatcattagg gttaaagaca tatgtggctg ctaattcacc tgccgacaag tcactctcag
    24721 gaatgaaatg atagtgacca ccatgtggta ctattagtag gttgaaatag aatatgagca
    24781 aattgataag gggattttaa agtaatttct aacaatgatt tagaaactat gatgtgctat
    24841 tctaaattca actcactata tataaccatc atcggtagta taacgtccct gtaattttgc
    24901 tacagatact tctgcactag ctcctttatc gtctttacca tgttcttgtt tttggcgatt
    24961 gatttcatct tttgttcgta cattttctgc atgagcttga tctttaaggt aaacataata
    25021 ctttccatct accttaataa tatatcctcc cttaacctaa ctgacgatat cttgatcttt
    25081 cggctgatag ttgggggctt tcattaatag ctcttcacta aagagcgcat caaaaggaac
    25141 tttaccatta tagtagtgat aatgatcgcc atgagaagtt acataacctt gacctgtaat
    25201 cttaataaca atttgttttg cttgaattcc ttctttttga ctaacctagt ctggagtcaa
    25261 attttcagtc ttcttagtgt ctttattact gtttacatat gaaacacgat ttttatctgt
    25321 attggcctgt tagctatgtt ggttcagagc ataaacacac agacttaagg aaaggataac
    25381 aacagatcca gctgctatat atttcttt
//
LOCUS       DAVLTT010000024        25281 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLTT010000024 DAVLTT010000000
VERSION     DAVLTT010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25281
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.024"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            1..1206
                     /locus_tag="VYN15_001113"
     CDS             1..1206
                     /locus_tag="VYN15_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1452442.1"
                     /translation="MDKKNEAFLIVSRGISRIGDIMFDFANNTFLAGLNPTSLSLVAV
                     YQSLESVIGVLFNLFGGVIADSFKRKKIIIVANILCGIACIILSFISQEQWMVFAIVI
                     TNIILAFMSAFSGPSYKAFTKEIVKKDSISQLNSLLEITSTIIKVTIPMVAILLYKLL
                     GIHGVLLLDGFSFLIAASLISFIVPVNDEVVTKDKMTIGGVLNDLKIGFKYIYSHKTI
                     FMIIILSAFVNFFLAAYNLLLPYSNQMFGEISDGLYGVFLTAEAIGGFIGAILSGVIN
                     KTLSSKRLMVFLSCSGLMLMLSTPLYFLFQNFIILAFSPALFSLFISIFNIQFFSIVQ
                     REVDTEFLGRVFGIIFTVAILFMPVGSGFFSVVLNPNNTFNLFIIGVSITILSLIFST
                     LLKRYDKNS"
     gene            1865..2086
                     /locus_tag="VYN15_001114"
     CDS             1865..2086
                     /locus_tag="VYN15_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1452443.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            2579..4381
                     /locus_tag="VYN15_001115"
     CDS             2579..4381
                     /locus_tag="VYN15_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1452444.1"
                     /translation="MSNNVEIIKANPLVTRRNDNSGSLSRRVAAYCRVSSDSDDQKNS
                     YDSQVRHYREYISQHQDWILVDIYADEGISGTQVGKRQDFQRLISDCLDGKIDYIITK
                     AIARFARNTLDTLKYVRLLKDKQIGVFFEEENIDTLTMDGELLLTILSSVAQQEVENT
                     SAHVKKGLKMKMQRGELIGFQGCLGYDYNQDTKSISINEKEAKIVRYIFERYIDGIGG
                     RAIARELDELGYKTPRGLDHWQDTTVLGIIKNEKYKGDILMGKTFTVDPISKRRLINF
                     GEEDKYYIKNNHDAIISPEIFTQAQEIRLRRSGNKKTIANTNGKRERYSRMYPFSSRL
                     ECGFCGTVLSRRSWHSSSEYKKIIWHCTTSIKRGKKHCTHSKGIEEKAIENAFLQSYQ
                     QLFYENNNLTEDFLEIIKEELTDDTLKVELNKIVSKLNSLYKKEEKLVSMNLDGKISD
                     SVYEDKFNQIQIEKEKLLEEKVNLEVTLKSEVDIKSRLENFKEILTSQKTLTEFDKDI
                     FESIVEKIIVGGINSDGEIDPSMLTIIFKTGDSSTKDAKSYKSKRKNAKIENDKLCFN
                     TVTDDEKKCTNKENSARGVCKLVAKSVKTLERKE"
     gene            4492..4731
                     /locus_tag="VYN15_001116"
                     /pseudo
     CDS             4492..4731
                     /locus_tag="VYN15_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            4875..6104
                     /locus_tag="VYN15_001117"
     CDS             4875..6104
                     /locus_tag="VYN15_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1452445.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            6124..8820
                     /gene="ppc"
                     /locus_tag="VYN15_001118"
     CDS             6124..8820
                     /gene="ppc"
                     /locus_tag="VYN15_001118"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV1452446.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    8903..9120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            9233..10237
                     /locus_tag="VYN15_001119"
     CDS             9233..10237
                     /locus_tag="VYN15_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1452447.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            10306..11172
                     /locus_tag="VYN15_001120"
     CDS             10306..11172
                     /locus_tag="VYN15_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1452448.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLLTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            11169..11927
                     /locus_tag="VYN15_001121"
     CDS             11169..11927
                     /locus_tag="VYN15_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1452449.1"
                     /translation="MTAIVELKNATKVVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLTSYKNEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLKQEEKAKMKISDYYQLFE"
     gene            12017..13777
                     /gene="dnaG"
                     /locus_tag="VYN15_001122"
     CDS             12017..13777
                     /gene="dnaG"
                     /locus_tag="VYN15_001122"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV1452450.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVAEDKQFYHCFGCGRSGDVFKFIEEYQGVPFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFRIGLAPPE
                     RNYLYQRLSGQYRDEDFLDSGLFYLSDANQFVDTFYNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRSGI
                     ENAVASMGTALSREHVEYLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSITAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            13780..14889
                     /gene="rpoD"
                     /locus_tag="VYN15_001123"
     CDS             13780..14889
                     /gene="rpoD"
                     /locus_tag="VYN15_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV1452451.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGIATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            14903..15232
                     /locus_tag="VYN15_001124"
     CDS             14903..15232
                     /locus_tag="VYN15_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1452452.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            15347..16390
                     /gene="cpoA"
                     /locus_tag="VYN15_001125"
     CDS             15347..16390
                     /gene="cpoA"
                     /locus_tag="VYN15_001125"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV1452453.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVE
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            16406..17731
                     /locus_tag="VYN15_001126"
     CDS             16406..17731
                     /locus_tag="VYN15_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1452454.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            17762..17938
                     /locus_tag="VYN15_001127"
     CDS             17762..17938
                     /locus_tag="VYN15_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1452455.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            17997..18131
                     /locus_tag="VYN15_001128"
     CDS             17997..18131
                     /locus_tag="VYN15_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV1452456.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            18195..19505
                     /gene="obgE"
                     /locus_tag="VYN15_001129"
     CDS             18195..19505
                     /gene="obgE"
                     /locus_tag="VYN15_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV1452457.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIVPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            19515..19673
                     /locus_tag="VYN15_001130"
     CDS             19515..19673
                     /locus_tag="VYN15_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452458.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            20722..21981
                     /locus_tag="VYN15_001131"
     CDS             20722..21981
                     /locus_tag="VYN15_001131"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1452459.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            21997..22548
                     /locus_tag="VYN15_001132"
     CDS             21997..22548
                     /locus_tag="VYN15_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1452460.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            22541..23818
                     /locus_tag="VYN15_001133"
     CDS             22541..23818
                     /locus_tag="VYN15_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1452461.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            23834..24694
                     /locus_tag="VYN15_001134"
     CDS             23834..24694
                     /locus_tag="VYN15_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV1452462.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            24919..25029
                     /locus_tag="VYN15_001135"
                     /pseudo
     CDS             24919..25029
                     /locus_tag="VYN15_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
     gene            25075..>25281
                     /locus_tag="VYN15_001136"
     CDS             25075..>25281
                     /locus_tag="VYN15_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEV1452463.1"
                     /translation="MNYEASKQLTDARFKCLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYE"
BASE COUNT         7938 a         4148 c         5512 g         7683 t
ORIGIN      
        1 atagataaaa aaaacgaggc tttccttatt gtaagtagag gcatatctcg aattggagat
       61 attatgtttg actttgcgaa taataccttt cttgcaggat taaatccaac atctttatca
      121 ttggttgcag tatatcagtc actagaaagt gtgataggtg ttctttttaa tttatttggt
      181 ggagtcattg cagatagttt caagcggaaa aaaattatta ttgttgcaaa tatcttatgt
      241 ggtattgctt gtataattct ttcattcata tcacaagagc agtggatggt ctttgcaatt
      301 gtcatcacta atattatctt ggcatttatg agtgcttttt ctggaccgtc ctataaagca
      361 tttacaaaag aaattgtaaa aaaggatagt atatcacaac ttaattcatt gctagagata
      421 acaagtacta taattaaagt aacaatacca atggtagcaa ttttattata taagctactt
      481 gggatacatg gtgttttact attggatgga ttctcatttc taattgctgc atcactgatt
      541 tcctttattg tacccgttaa tgacgaagtg gtcacaaagg ataaaatgac aataggagga
      601 gttttaaatg acttaaaaat agggtttaag tatatttata gtcataagac aatatttatg
      661 attattattc tctctgcttt tgttaatttt tttctagcag cttataattt attgttacct
      721 tatagtaatc aaatgtttgg agaaatttca gatgggcttt atggtgtttt tctaactgcg
      781 gaagcaattg gaggatttat tggagcgata ttaagtggtg ttataaataa aaccttgtca
      841 agcaaacgtt taatggtctt cttatcatgt tcaggattga tgttaatgct atcaacgcca
      901 ctctattttt tgtttcaaaa cttcattatt ctagcctttt ctccggcatt atttagtcta
      961 tttatttcta tttttaatat tcaatttttc tctattgttc aaagagaagt tgatactgag
     1021 tttctcggta gagtctttgg aatcatcttt acggtagcta ttctttttat gccagttggg
     1081 tctggatttt tctcagtagt tttaaatcct aacaatactt ttaatctttt tattattggt
     1141 gtatctatta cgatattatc gctaatattc agcacgctat tgaagaggta tgataaaaat
     1201 agctgatata gagaatttag agcgcctttg gaatatattt ttggaattta atcaatcaca
     1261 gttgaatgtg aagggcaatc tgttttagaa gaatacaatc aagatatcat tatgctatta
     1321 ctttagttca gttaaaatat tgagaagtat tacttttatt taaaaagcat cataaaggac
     1381 tccaattaat ttttaatgat ttttctaatc taattttgtg gttattgaca aataaagtct
     1441 agttaattgc tttgaaatcc atggattggt ttatatacat ctgttaatgc aacggataat
     1501 tttattgata agtagggagt ggctattatt caacttttag gttctgaaag taagagattc
     1561 atattagaaa tatcatgttg accatttttc aatttgctgg ttagtagtaa tctggacatc
     1621 attaatccct tccttaacaa aattatgtga cttttgttac cggattactg ctgatttttt
     1681 aatagcttat aacattttta gacggttaat agattttgac cgtctttctt aatattgtct
     1741 tacctataat agatatgctt atgagatatg tttaataaat taattttagt tcaaaatgtc
     1801 cagttaggac actttgaatg atttcttagt tttatatatt atacttttct caggagaaag
     1861 ctagatgtac agacgtttga gagatttgag ggaagatcac gatttgaccc aaaaacaaat
     1921 agctaaaata ctttcgttta caaactcagc ttatgctaaa attgaacgag gtgagcatac
     1981 gttaacagca gatgtattgg taactctctc aaacttttac gatgtcagta cagactacct
     2041 attggaattg acagattttc ctgataaaat tcgctttaga aaataatctc ctcaatttca
     2101 tagagtgtga aaatgaggag attattttat ttggttcttt gacaattaaa tagtccaaaa
     2161 tggtactttc ctcatttgtg gagcagtttt gaatggctcg ccatgataag agcgacataa
     2221 aaaccatcaa taaaatagag cgatacttta tatgccatga tacaaatgat atacaatgat
     2281 acttctgacc gttcaggctg ccaccgtaaa agagcagcaa gtgaaattct tatgatgact
     2341 tcatcagtca tgccatggag gagattgata aaagataaaa gggaagtgat tttttgaaat
     2401 caaatttaga aaattatata gtcgagctag agatgctaaa tctattattc ttaaaaaaac
     2461 ttattagcga aaaagaatat gaaaaaataa agctgaaact gcgtaaaata tatacaaatt
     2521 agctgacctt ttttattggt tgcggtaaaa taattgcaga gaaataggag gttcagccat
     2581 gtcaaataac gttgaaatta taaaagcaaa tcctttagta actagaagaa atgataatag
     2641 tggttcttta tcgaggagag tagcagcata ttgtcgtgtt agttccgata gtgatgatca
     2701 aaaaaatagc tatgattctc aagttcgtca ttatagagag tatatatcac agcaccaaga
     2761 ttggattttg gttgacattt atgctgatga agggatttca ggaactcaag ttggaaaaag
     2821 acaagatttt caaagattaa tttcagattg ccttgatgga aaaatagact atatcattac
     2881 caaagccatt gctcgctttg ctagaaatac attagatact ctcaaatatg ttcgtttgct
     2941 caaagataaa caaattggtg tatttttcga agaagaaaat attgatactt taactatgga
     3001 tggtgagtta ctattgacga tattaagttc agtggctcaa caggaagttg aaaatacatc
     3061 tgcccatgtt aaaaagggtt taaaaatgaa gatgcaacgt ggagaactta ttggttttca
     3121 aggttgtctt ggttatgact ataatcaaga tacaaagtcg atatcaataa atgaaaaaga
     3181 agccaagata gtacgttata tttttgaacg atacattgat ggtattgggg gtagggcaat
     3241 agctagagaa cttgatgaac taggttataa aactccgaga ggtctggatc actggcaaga
     3301 tacaacagtt ttaggaatta ttaaaaacga gaagtataaa ggtgatattc taatgggaaa
     3361 aactttcact gttgacccca ttagtaagag acgtttaata aatttcggtg aagaagataa
     3421 atactacatt aaaaataacc atgatgcaat aattagtcca gaaattttta cacaggcgca
     3481 agaaattcga ttacggagat caggaaacaa aaaaaccata gcaaatacaa atggtaaacg
     3541 agaaagatat tcaagaatgt acccttttag cagtagatta gaatgtggtt tttgtggtac
     3601 tgttctgtct agaagaagtt ggcactctag ttcagaatac aaaaaaatta tttggcactg
     3661 tacaacatct ataaagagag gtaaaaagca ttgcactcat agtaaaggaa tagaggaaaa
     3721 agcaatagaa aatgcttttt tacagagcta ccaacagttg ttttatgaaa ataataacct
     3781 aactgaagac tttcttgaaa ttataaaaga agagcttact gatgatacct taaaagtgga
     3841 gttaaataag atagttagta aattaaattc gttgtacaaa aaagaagaaa aattagtttc
     3901 aatgaatcta gatggaaaaa taagtgattc tgtatatgaa gataaattca atcaaataca
     3961 aattgagaaa gaaaaacttt tagaagaaaa ggtaaactta gaagtaactt taaaatcaga
     4021 agttgatata aaaagtagat tagagaattt taaagaaatt ttaacttcac aaaagacttt
     4081 gacggagttt gacaaggaca tttttgaaag tatcgttgaa aaaataatag taggcggaat
     4141 aaattctgat ggagaaattg atccatcaat gttgactata atttttaaaa cgggagattc
     4201 ttcgactaaa gatgcaaaat cttacaaatc taaaagaaag aatgctaaaa tagaaaatga
     4261 taaattgtgt tttaataccg taaccgatga cgaaaaaaag tgtacaaata aagaaaacag
     4321 cgcacgtgga gtgtgtaagc ttgttgctaa aagcgtaaaa accttggaac gaaaggaata
     4381 atagacttcc tgcgaaacaa aaatacaata caataaaact atggatgatg aagcaagtaa
     4441 acaattaagc gatagccgtt tcaagagcct tgtaggtgtt cagcgcacga gatgttagct
     4501 gtgttaaaaa cagcttatca acgcaacgta aacgcgcaaa aggtggacga aaaaccaaat
     4561 taagcctaga cgatctcctc atggtaacta ttcaatacat gcgagaatag cgcacttatg
     4621 aacaaattgc ggctgatttt ggcattcacg aaagcaacat aattagtcgg aggtcaatgg
     4681 attgaagcaa ctcttattca aaatggtttt acgatttcaa attctgcctt aattctgtaa
     4741 aaacagtaaa attcgaagga ttgtaaggta agagtttttt tctttctgaa aaaatggtat
     4801 aatagcaatc aaaactagaa aataaaacgg aatttggaac agatttgtct gtatcctagt
     4861 agagtggtga tactatgaag attagtaaga ggcacttatt aaattattcc atcttgattc
     4921 cctacttgct tttatctatt ttgggcttga ttgtggtcta ttcgaccacc agtgctattt
     4981 taattgaaga aggcaagagc gccttgcagt tggttcgaaa ccaaggaatc ttttggattg
     5041 ttagtttgat actgattgcc ttaatttata aattgagact agattttttg agaaatgagc
     5101 gactaatcat tttagttata ttaatagaaa tgcttttatt gttcttggct cgttttattg
     5161 gtatttcagt aaacggggca tacggttgga tttcggttgc aggagtaact attcagccag
     5221 ctgagtactt aaaaatcatt attatttggt atttagctca ccgattctcc aaacagcaag
     5281 aagaaatagc tacttatgat tttcaagttt tgactcaaaa tcaatggctt ccccgtgctt
     5341 ttaatgattg gcgattcgtt ctcctagttc tgattggaag tttgggaatt ttccctgatt
     5401 taggaaatgc gactatttta gtcttggttt ccttgattat gtatacagtt agtggaatcg
     5461 cttatcgctg gttttcaacc attctggcgc tcgtatctgc cgcttctgtc tttgtcttga
     5521 ccactatcag cctaatcggt gttgagacct tttcaaaaat tccagtattt ggctatgtag
     5581 ccaaacgctt tagtgccttt tttaatcctt ttgccgatcg tgctgatgca ggtcaccagt
     5641 tagctaattc ttattttgcc atggtcaatg gtggttggtt tggtctaggt cttggaaact
     5701 cgattgaaaa acgaggttat ttgccagaag ctcatacaga ctttgtcttt tctatcgtga
     5761 ttgaagaatt tggctttgtt ggtgccagtc ttattttagc tctcttgttt ttcatgattt
     5821 tgcggattat cttggtcggt attcgagcgg agaatccttt caatgccatg gttgcactcg
     5881 gtgtcggagg gatgatgttg gttcaggtat ttgtcaatat cggagggatt tcgggcttga
     5941 ttccatctac aggagtaacc ttccccttct tatcccaggg tggaaatagt cttctagtct
     6001 tatcagtggc agtagccttt gtcttaaata ttgatgccag tgaaaaacgc gctaagttgt
     6061 accgagaatt ggaaaatcaa ccaatgaacc ttctgttgaa gtaggataaa gaaaggatag
     6121 tttatgtctc ttcaaaaatt agaaaattct agtaataaaa gtgttgtgca agaagaagtc
     6181 ttgattctaa cagaattact ggaagatatt actaaaaata tgcttgcccc agagaccttt
     6241 gaaaaaataa tacagttgaa agaattatca acgcaggaag attatcaagg tctaaaccgt
     6301 ctagtgacta gcttatcaaa tgatgaaatg gtctatattt cacgctattt ctctatcttg
     6361 cctcttttga ttaatatttc agaggatgtg gatttagctt atgaaatcaa tcatcaaaat
     6421 aatattgatc aggactattt aggtaaatta tctacaacga ttaaattggt agcagaaaag
     6481 gaaaatgccg ttgagatcct agaacacttg aatgttgttc cagttttgac agcccatcca
     6541 acacaagtgc aacgcaaaag tatgttggat ttaacaaatc atattcatag tcttttgcgt
     6601 aaataccgtg atgttaagtt ggggttgatc aataaagata aatggtacaa tgatttgcgt
     6661 cgttacatcg aaattatcat gcagacagac atgattcgtg agaaaaaatt aaaagtgact
     6721 aacgaaatca cgaatgctat ggaatattat aacagctcct ttttgaaagc tgtacctcat
     6781 ttgacgacgg agtataagcg cttagcgcaa gcgcatggtc tgaatttaaa acaggctaaa
     6841 ccaatcacca tgggtatgtg gataggtggt gaccgtgatg gaaatccatt tgttacagca
     6901 aagaccttga agcagtctgc actcactcag tgtgaagtca tcatgaacta ctatgataaa
     6961 aagatttacc aactttatcg tgaattttct ctttcaacta gcattgtcaa cgtcagcaag
     7021 caagtcagag aaatggctcg tcaatccaag gataactcga tttaccgcga aaaagagctt
     7081 taccgtcgtg ccttgtttga tattcaatca aaaattcagg caactaaaac ctatctgatt
     7141 gaggatgaag aagttgggac tcgttatgaa accgccaatg atttctacaa ggatttgatt
     7201 gccattcgag attctctact agaaaataag ggcgagtcct tgatttcagg tgattttgtg
     7261 gaattattgc aggcagtaga gatatttggt ttttacttag catcaattga tatgcgacaa
     7321 gactctagcg tctatgaagc ctgtgtggca gaactcttga aatcagcagg aattcattct
     7381 cgttatagcg agttgagcga agaagaaaag tgtgaccttc tcttgaaaga attagaagaa
     7441 gatccccgaa ttctttctgc gactcacgca gaaaaatcag aattattagc aaaagaacta
     7501 gctattttta agacggctcg tgttttgaaa gataagttgg gagatgatgt catccgtcag
     7561 accatcattt cacatgcaac cagcctttct gatatgctag aattagctat tctgttaaaa
     7621 gaagtaggac tggtggatac ggaaagggcg cgtgttcaga ttgttcccct ttttgaaaca
     7681 attgaagact tggatcattc agaggaaaca atgagaaaat atctttctct tagccttgcc
     7741 aaaaaatgga ttgactcacg aaataactac caagaaatca tgcttggcta ctctgacagt
     7801 aataaagatg gcggttactt gtcatcatgt tggaccctct acaaggctca acaacaattg
     7861 actgctattg gagatgaatt tggcgttaag gttaccttct tccatggtcg tggtggtact
     7921 gtcggtcgtg gtggtgggcc aacctatgaa gccattacat ctcaaccgct caagtctatc
     7981 aaggatcgta tccgcttgac ggagcagggt gaagtaattg ggaataaata cggtaacaaa
     8041 gacgccgctt actataacct tgaaatgcta gtatcggcag ctattaaccg tatgattact
     8101 cagaagaaga gcgataccaa taccccaaat cgttatgaag ccattatgga tcaagtagtg
     8161 gaccgtagtt acgatatcta ccgtgatttg gtctttggta atgagcattt ctatgattat
     8221 ttcttcgagt caagtccaat caaggctatt tcaagtttta atattggttc tcgtccagcc
     8281 gctcgtaaga ctattactga aatcggtgga ttgcgtgcta tcccttgggt attctcatgg
     8341 tcacagagtc gtgttatgtt ccctggatgg tacggggttg gttcaagctt caaggaattt
     8401 atcaataaaa atccagagaa tattgctatc ttacgagata tgtaccaaaa ttggcctttc
     8461 ttccaatcgc ttctttcaaa tgttgatatg gttttgtcaa aatcaaatat gaatattgct
     8521 tttgaatatg ctaaactttg tgaagacgag caagttaagg ccatctatga gactatttta
     8581 aatgaatggc aagttactaa gaacgttatc ttggctattg aaggacatga cgaactctta
     8641 gctgacaatc catatctaaa agctagtctg gattaccgta tgccttactt taatattctc
     8701 aactatattc agttagagtt gattaaacgc caacgtcgtg gagaattgtc cagtgatcaa
     8761 gaacgattga ttcatatcac catcaacgga attgcgacag gattgcgtaa ttcaggttga
     8821 taattttcaa gagtgaatgc taaaagtgaa tatcaaaaaa attctaatag actattgaca
     8881 agtagtttaa aaatgatata atttaaccat tcagaaaagt aatcatacaa actttttaga
     8941 gagtctgtgg tagctgaaaa cagataagtg gcaatgatga aaattgggct gaatgctatt
     9001 tagaatttga aattataaaa attcggtaag cacaccttac agtgcatctc gttattgcga
     9061 gactgagcga tagggaaatt ccctataatt gaggtggtac cgcgcatcga cgtcctcaca
     9121 caagtttttt gtgtgaggat ttttttgatg gaggttagta tggaaagaaa acgatggcat
     9181 cgcttgttta gataagtgaa atatgttaaa ggaaataaaa aggagaaaca gaatgaaaaa
     9241 taaacgttta attggaatta ttgctgcatt agcagtctta gtagcaggaa gcttgattta
     9301 ttcttcaatg aataaatcag aagctcagaa taataaggat gagaagaaaa taaccaagat
     9361 tggtgtgctt caatttgtga gccatccatc ccttgatttg atttataaag ggatccaaga
     9421 tggacttgca gaagaaggat ataaagatga tcaagttaaa attgatttta tgaactcaga
     9481 aggtgaccaa agtaaggttg cgacaatgag taaacaattg gttgcaaatg ggaatgacct
     9541 tgtggttggt atcgcaacac cagcagccca agggttggct agtgcaacaa aagacctacc
     9601 agttatcatg gccgctatta cagacccaat tggtgctaac ttggttaaag atttaaaaaa
     9661 accaggtggc aacgttacag gggtatctga ccacaatcca gctcaacaac aaattgaact
     9721 catcaaggct ctgacaccga atgtgaaaac aatcggagct ctttactcaa gtagcgaaga
     9781 caattcaaaa acacaggtcg aagaatttaa ggcttatgct gaaaaagcag gtctgacagt
     9841 ggaaacattt gcagttcctt caacaaatga aattgcctca actgtcactg ttatgactag
     9901 caaggtagat gctatttggg ttccaattga taacaccatt gcatcaggat ttccaacggt
     9961 tgtctctagc aatcaaagtt ctaagaaacc aatttatccc agtgcgacag ctatggtaga
    10021 agtaggtggt ttggcatcag ttgtaattga ccaacatgac cttggtgtgg caacaggtaa
    10081 aatgattgtg caagtcttga aaggtgcaaa accagccgat accccagtca atgtcttttc
    10141 aactggtaag tcagtcatca ataaaaaaat agcacaagaa ctaggtatta ctattcctga
    10201 gtctgttctc aaagaagcag gacaagtcat cgaataaata aggtagggag gaggagactc
    10261 ttcccatttt ttaaaaagat gaatatagaa aggattaaat aaaatatgat tgtttccatt
    10321 atttctcaag gatttgtctg ggctattcta ggtctgggaa tctttatgac atttaggatt
    10381 ttaaactttc cagatatgac gacagaaggt tccttccctc ttgggggagc tgttgctgtc
    10441 actttgataa ccaaaggcgt gaacccattt ttagcgacac ttgttgctgt aggagcaggt
    10501 tgtttggctg gaatggcagc aggccttctt tatacaaaag ggaagatccc aaccttgctc
    10561 tcagggattt tggtgatgac ttcttgtcac tcaatcatgc tcttgattat gggacgtgcg
    10621 aatttaggcc tgcttggaac taagcaaatt caggatgttt tgccttttga ttcggatttg
    10681 aatcaactct tgacaggtct catctttgtg agtattgtta ttgctctcat gctctttttc
    10741 ttggacacta aactcggaca agcctatatt gctacagggg ataatcctga tatggctaga
    10801 agtttcggga ttcatactgg acgcatggag ctcatgggct tggtcttatc aaatggtgtg
    10861 attgcccttg caggtgccct cattgctcag caagaaggtt atgccgatgt gtctcgaggg
    10921 atcggggtta tcgttgtggg gcttgcaagt ttgattattg gagaagttat tttcaagagt
    10981 ttgagcttgg cagagcgttt gcttactatc gttgtaggtt ctatcgctta tcaattttta
    11041 gtgtgggcag ttatcgcact tggctttaat acaagttacc ttcgtttata cagtgccttg
    11101 attttagcag tctgcctcat gattccaaca tttaagcaaa caatcttgaa aggagccaaa
    11161 ttaagcaaat gacagcaatt gtagaattaa aaaatgcaac caaagtcgtt aaaaatggct
    11221 ttgatgaaga aaagattatc ttaaatgatg tttccttaga aatttttgaa caggatttca
    11281 tcacgatttt aggtggaaat ggtgctggga agtcaactct ctttaacact attgcaggaa
    11341 ccttgtcatt aaccagtgga accatccgta ttttgggtga agatgttacc aagttttcac
    11401 cagagaagcg ggctaagtat ctgtctcgag tcttccaaga tcccaagatg gggacagctc
    11461 cccgtatgac ggtcgctgaa aatctcctga ttgcaaagtt tcgtggtgaa aagcgtggac
    11521 tatttccacg acgcttgact agttataaga atgaatttca ggcgaccatt gaaaaagtag
    11581 gaaatggtct tgagaaacat ttgaatacac cgattgagtt cttatcaggt gggcaaagac
    11641 aggccttgag tctcttgatg gcaaccttga agcggcctga attactcttg ttagacgagc
    11701 atactgcggc ccttgatcca aagaccagtg tggccttgat ggaattgaca gacgaatttg
    11761 tcaagaaaga ccagttgaca gctcttatga ttacccacca tatggaagat gctcttaagt
    11821 atggcaatcg cttgattgtc atgaaagaag gacgggttat ccaagatttg aaacaagaag
    11881 aaaaagcaaa aatgaaaatc tctgattatt atcaactctt tgaataaagt agggaaaatg
    11941 agtgaaatgg tttacttttt ttctgaaata aagtatacta tataaagtaa actatgataa
    12001 catggaggta ttgtgtatgg ttgacaaaca agtcattgaa gaaatcaaaa acaatgccaa
    12061 cattgtggaa gtcataggag atgtgatttc tttacaaaag gcaggacgga actatctagg
    12121 gctctgtcct tttcatggtg aaaaaacacc ttctttcaac gttgcagagg acaagcagtt
    12181 ttaccactgt tttggttgtg gtcgctcagg tgatgtcttt aaattcatcg aggagtacca
    12241 aggggttccc tttatggagg ctgtccaaat cttaggtcag cgtgttggga tagaggtgga
    12301 aaaaccgctt tatagtgagc agaagccagc ctcgcctcac caagctcttt atgatatgca
    12361 cgaagatgcg gctaaatttt atcatgctat tctcatgaca acgaccatgg gggaggaggc
    12421 cagaaactac ctttatcagc gtggtttgac agatgaagtg ctcaagcatt ttcggattgg
    12481 tttagcacct ccagaacgaa actatctcta tcaacgtttg tctggtcagt atcgtgatga
    12541 ggatttccta gattcaggac tgttttatct ctcggatgca aatcaatttg tagacacctt
    12601 ttacaatcgg attatgtttc ccctgacaaa tgaccaggga aaggttattg ccttctcagg
    12661 tcgtatctgg cagaaaacgg attcacaaac ttctaagtat aaaaatagcc gatcgactgc
    12721 aatttttaac aaaagttacg aattatatca tatggatagg gcaaaaaaat cttctggaaa
    12781 agccagcgag atttacctga tggaaggatt catggatgtc attgcagctt atcggtctgg
    12841 aatcgaaaac gctgtcgcat ctatgggaac agccttgagt cgtgagcatg ttgagtatct
    12901 gaaaaggtta accaagaagt tggttcttgt ttacgatggc gataaggctg ggcaagctgc
    12961 gacattgaaa gcgctggatg aaattggcga tatgcctgtg caaatcgtca gcatgcctga
    13021 taacttggat ccagatgagt atctacaaaa aaatggacca gaagatttgg cctatctatt
    13081 aacgaaaact cgtattagtc cgattgagtt ttacattcac cagtataagc ctgaaaatag
    13141 tgaaaatctg caggctcaga ttgagtttat tgaaaaaata gctcccttga ttgttcaaga
    13201 aaagtctatc actgctcaaa acagctatat tcatatttta gctgacagtc tagcatcctt
    13261 tgattatgcc cagattgagc agattgttaa tgagagtcgt caggtgcaaa ggcagaatcg
    13321 catggaaaga atttccagac cgacgccaat caccatgcct gtcaccaagc agttatcggc
    13381 tattatgagg gcagaagccc atctactcta tcggatgatg gaatcccctc ttgttttgaa
    13441 cgattaccgt ttgcgagaag actttgcatt tgctacacct gaatttcagg tcttatatga
    13501 cttgcttggc cagtatggaa atcttcctcc agaagtttta gcagagcaga cagaggaagt
    13561 tgaaagagct tggtaccaag ttttagctca ggatttgcct gctgagatat cgccgcagga
    13621 acttagtgaa gtagagatga ctcgaaacaa ggctctcttg aatcaggaca atatgagaat
    13681 caaaaagaag gtgcaggaag ctagccatgt aggagataca gatacagccc tagaagaatt
    13741 ggaacgttta atttcccaaa agagaagaat ggagtaataa tggcaacaaa acaaaaagaa
    13801 gtaacaacat ttgacgtaca ggtagcagaa tttatccgta atcataagca aaaagggata
    13861 gcaacagatg atgaaatcaa tgcaagtctg gttattcctt ttaccttgga cgctgatggg
    13921 attgaagatc tcttgcaacg gattcaggat gcaggcattt ctatcacaga taacgaagga
    13981 aatccaagtg cgcgtgttct tagcaatgaa gaagaaccag aactcagcga tgaggacttg
    14041 attgggtcaa cttctgctaa ggtcaatgac cctgtccgta tgtacttgaa agaaataggg
    14101 gtcgttcctc tcttgaccaa tgaagaggag aaagagttgg cactggctgt tgaagctggt
    14161 gatatcgaag ccaaacaacg tcttgcggaa gccaatcttc gtttggttgt ttccattgcc
    14221 aaacgctatg tcggtcgtgg catgcagttc cttgacttga ttcaagaagg aaatatgggc
    14281 ttgatgaagg cggttgacaa gtttgactat tctaaagggt tcaagttttc aacttatgca
    14341 acttggtgga ttcgtcaggc tatcactcgt gctattgcgg accaagctcg taccatccgt
    14401 atcccagttc acatggttga aactatcaat aaattggttc gtgaacagcg gaatctcctt
    14461 caagaattgg ggcaagatcc gacaccagaa cagattgctg aacgaatgga tatgacacct
    14521 gataaggttc gtgaaatctt gaagattgcc caagaaccag tatctcttga aactcctatc
    14581 ggtgaagagg acgatagcca ccttggagac tttatcgaag atgaagtgat tgaaaatcca
    14641 gtggattata cgactcgtat cgtcttgcgt gagcaattgg atgaaatctt agatactctt
    14701 acagaccgtg aagaaaatgt tctgcgtcta cgttttggac tagatgatgg aaaaatgcgc
    14761 acacttgaag atgtggggaa agtctttaac gtaactcgtg agcgtatccg tcagattgaa
    14821 gcaaaggctt tgagaaaact acgccaacca agtcgtagca aaccgcttcg tgattttatt
    14881 gaagactaag agtgaggaaa atatggctta tacagaagag caaattgaaa atatcaaaac
    14941 acggatttta acagccttgg aagaagtcat cgaccctgag ttgggaatcg atattgtcaa
    15001 tcttggtttg atctatgaga ttcgttttga cggtgacaca gggcaaacag agattgacat
    15061 gactttgaca actatgggtt gtcccttagc agaccttttg acagaccaga tttatgatgc
    15121 tatgatagag gttccagaag taacggatac tgaggttaaa ttagtctggt atccagcctg
    15181 gacagttgaa aaaatgagtc gctatgcccg cattgcccta ggcattaagt aaacatataa
    15241 aagcatgtga gagactgttg gaaaagcgag gaaatttccc ctcttttcct ctagtctctc
    15301 ctttcttttg ctgattttat tcaaagaaaa tgatataata gtagttatgg agaaaaagaa
    15361 attacgcatc aatatgttga gttcaagtga gaaagtagca ggacagggag tttcaggtgc
    15421 ttaccgtgaa ttagttcgtc ttcttcaccg tgctgccaag gaccaattga ttgttacaga
    15481 aaatcttcca atcgaggcag atgtgactca ctttcatacg attgattttc cctattattt
    15541 atcaaccttc caaaagaaac gctcagggag aaagattggc tatgtgcatt tcttgccagc
    15601 tacacttgag ggaagtttga aaattccatt tttcttaaag ggaattgtgg aacgctatgt
    15661 attttctttt tacaaccgga tggagcactt ggttgtggtc aatcctatgt ttattgagga
    15721 tttggtagca gctggtattc cacgtgaaaa agtgacctat attcctaact ttgtcaacaa
    15781 ggaaaaatgg catcctctac cacaagaaga ggtagttaga ctgcgcacag atcttggtct
    15841 tagtgacaat cagtttatcg tagtaggtgc tgggcaagtt cagaaacgta aagggattga
    15901 tgactttatc cgtctggctg aggaattgcc tcagattacc tttatctggg ctggtggctt
    15961 ctcttttggt ggtatgacag atggttatga acactataag aaaattatgg aaaatccccc
    16021 taaaaatttg atttttccag gcattgtatc gccagagcgg atgcgcgaat tgtatgctct
    16081 agcggatctt ttcttgttgc ctagttacaa tgagctcttt cctatgacta ttttagaagc
    16141 tgcgagttgt gaggctccta ttatgttgcg tgatttagat ctctataagg tgattttgga
    16201 gggaaattat cgggcgacag cgggtagaga agagatgaaa gaggctattt tggaatatca
    16261 agcaaatcct gctgccttaa aagatctcaa agaaaaggct aagaatattt ccagagagta
    16321 ttctgaagag catctgttac aaatctggtt ggacttttat gagaaacaag ccgctttagg
    16381 gagaaagtaa aaagtgaggt aatctatgcg aattggttta tttacagata cctattttcc
    16441 tcaggtttct ggtgttgcga ccagtattcg aaccttgaaa acagaacttg aaaagcaggg
    16501 acatgctgtt tttatcttta cgacgacaga taaggatgtc aatcgctacg aagattggca
    16561 aattatccgc attccaagtg ttcctttctt tgcttttaag gatcgtcgct ttgcctaccg
    16621 aggttttagc aaggcacttg aaattgctaa acagtatcag ctagatatta tccatactca
    16681 gacagaattt tctcttggcc tgttggggat ttggattgcg cgtgaattga aaattccagt
    16741 catccatacc tatcacaccc agtatgaaga ctatgtccat tatattgcta aggggatgtt
    16801 gatccggccg agtatggtca agtatctggt tagaggtttc ctgcatgatg tggatggggt
    16861 tatttgccct agtgagattg tccgtgactt gctatctgat tataaggtca aggttgaaaa
    16921 acgggtcatt cctactggga ttgaattagc caagtttgag cgtccggaaa tcaagcagga
    16981 aaatttgaaa gaactgcgta gtaaactagg gattcaagat ggtgaaaaga cgttgcttag
    17041 tctttcgaga atctcctatg aaaaaaatat tcaagcagtt ttagtagcct ttgctgatgt
    17101 tctgaaagag gaagataagg ttaaactggt agtagctggg gatggccctt atctgaatga
    17161 cctcaaagag caagcccaga acctagagat tcaagactca gtcatcttta cagggatgat
    17221 tgctcctagt gagacggctc tttactataa agcggcggat ttcttcattt cggcatcgac
    17281 aagcgaaacg caaggtttga cctacttgga aagcttagcc agtggaacac ctgtcattgc
    17341 tcacggaaat ccttatttga acaacctcat cagtgataaa atgtttggaa ccttgtacta
    17401 tggagaacat gatttggctg gtgctatttt ggaagccctg attgcaacac cagacatgaa
    17461 cgagcatacc ttatcagaga aattgtatga gatttcagct gagaactttg ggaaacgagt
    17521 gcatgagttt tatctggatg ccattatttc aaataacttc cagaaagatt tggctaaaga
    17581 tgatacggtc agtcagcgta tctttaagac agttttgtat cttccgcaac aggtggttgc
    17641 tgtacctgta aaaggatcta gacgcatgtt gaaggcttca aaaacacagt tgatcagtat
    17701 gagagactat tggaaagacc atgaagaata gaaagaggaa cagctatgaa aaaaacaatt
    17761 aatgagaagc ggtcgtgata aaaagattgc gggtgtttgt gctggggtgg cccattatct
    17821 ggatatggat ccgactatcg ttcaagtcat ttggggtgtt cttacttgct gttacggagc
    17881 tggaattgta gcttacatta ttttatggat tatcgcacca gtagcaactg actattgaaa
    17941 actagctcaa ttcatgctaa gataatagaa aatagaatgt aacgaaggag agaaaaatgg
    18001 catttggaga taatggaaat cgtaaaaaaa ctatgtttga gaaaataacc ttgtttatcg
    18061 tgattatcat gctagtagca agtttattgg gaatttttgc aactgcaatt ggtgccctca
    18121 gtaatctata aaatagattc aagaaaattt agtgactggg atttcccagc ccttttttaa
    18181 agtgagaaga aataatgagt atgtttttag atacagctaa gattaaggtc aaggctggta
    18241 atggtggcga tggtatggtt gcctttcgtc gtgaaaaata tgtccctaat ggaggccctt
    18301 ggggtggtga tggtggtcgt ggaggcaatg tggtcttcgt tgtagacgaa ggactacgta
    18361 ccttgatgga tttccgctac aatcgtcatt tcaaggctga ttctggtgaa aaagggatga
    18421 ccaaagggat gcatggtcgt ggtgctgagg accttagagt tcgagtacca caaggtacga
    18481 ctgttcgtga tgcggagact ggcaaggttt taacagattt gattgaacat gggcaagaat
    18541 ttatcgttgc ccacggtggt cgtggtggac gtggaaatat tcgtttcgcg acaccaaaaa
    18601 atcctgcacc ggaaatctct gaaaatggag aaccaggtca ggaacgtgag ttacaattgg
    18661 aactaaaaat cttggcagat gtcggtttag taggattccc atctgtaggg aagtcaacac
    18721 ttttaagtgt tattacctca gctaagccta aaattggtgc ctaccacttt accactattg
    18781 taccaaattt aggtatggtt cgcacccaat caggtgaatc ctttgcagta gccgacttgc
    18841 caggtttgat tgaaggggct agtcaaggtg ttggtttggg aactcagttc ctccgtcaca
    18901 tcgagcgtac acgtgttatc cttcacatca ttgatatgtc agctagcgaa ggccgtgatc
    18961 catatgagga ttacctagct atcaataaag agctggagtc ttacaatctt cgcctcatgg
    19021 agcgtccaca gattattgta gctaataaga tggacatgcc tgagagtcag gaaaatcttg
    19081 aagaatttaa gaaaaaattg gctgaaaatt atgatgaatt tgaagagtta ccagctatcg
    19141 tcccaatttc tggattgacc aagcaaggtc tggcaacact tttagatgct acagctgaat
    19201 tgttagacaa gacaccagaa tttttgctct acgacgagtc cgatatggaa gaagaagctt
    19261 actatggatt tgacgaagaa gaaaaagcct ttgaaattag tcgtgatgac gatgcgacat
    19321 gggtactttc tggtgaaaaa ctcatgaaac tctttaatat gaccaacttt gatcgtgatg
    19381 aatctgtcat gaaatttgcc cgtcagcttc gtggtatggg ggttgatgaa gcccttcgtg
    19441 cgcgtggagc taaagatggg gatttggtcc gcattggtaa atttgagttt gaatttgtag
    19501 actaggagac tggtatggga gataaaccga tatctttccg agatgcggat ggtaattttg
    19561 tttccgccgc agacgtttgg aatgaaaaga aattggaaga actatttaat cggctcaatc
    19621 caaatcgtgc cttgagattg gcacgaacta aaaaggaaaa tccatctcag taaagaagct
    19681 aaaaaatccc gtgcctcatc agacacggga ttttgtggta cgacaggcat gtatagcaaa
    19741 ctgaatctgg aatagcacag catatcttct aaaatattgt tataaattga tttgaatttc
    19801 aaaattaaat tgtttgattc ttatttcaat ttgttatagt atatctgatg tcaaagttct
    19861 cggcgagtca aatagcgatt cccaagcctg actatcgtga ggtagcggat taaaatggtc
    19921 tggggataga ccgttttaag tctgacgctg gaaataagaa ttgtcagaag aagggatagc
    19981 gaaatcgcgg ctctacgaac aggaacgtga taataaggcg tatatagcgg ataagagggc
    20041 ctcaaactct aaagtccaaa aaggtagtcg taacctatat gcgtaaatca cgagagtaat
    20101 tgaattcgta ctaagatttt ctattttcac tgtaaccttt taacgtcctt atatcttgta
    20161 tacacgagga aagatgtacg atttatcccg tgaggtctat cactataaag agaaaacgac
    20221 agatagaagt gatcctgagt cacggttatc tttaaaatag attgtctgat aggacggtat
    20281 gtataaaacg cttctgtgaa ctgagagaag gggagaagtt cttgctaaaa tttagttgaa
    20341 cagccgtatt ccgatactta gataagagat ctagtcttag ctcctactca gttttagggg
    20401 ataaaaaagg ggcaatagcg attcgagaaa gattatactc ttcgaaaatc tcttcaaatc
    20461 acgtcaatat cgccttgccg tatgtgtagg atactgacta cgtcagttcc atctacaacc
    20521 tcaaaacagt gttttgagca acctgcggtt agtttcctag tttgatcttt gattttcatt
    20581 gagtattagt aattcagtta ctaactcgtc aactatgatt tatccaataa aattgaaaag
    20641 gatggaaaaa aggataaatt tatgatatac tttattttga agaccttatt agaaatcttg
    20701 aaagagtatt gaaaacttag aatgagaaaa attgttatca atggtggatt accactgcaa
    20761 ggtgaaatta ctattagtgg tgctaaaaat agtgttgtgg ccttaattcc agctattata
    20821 ttggctgatg atgtggtgac tttggattgt gttccagata tttcggatgt agccagtctt
    20881 gtcgaaatca tggaattaat gggagctact gttaagcgtt atgacgatgt cttggagatt
    20941 gatccaagag gtgttcaaaa tattccaatg ccttatggta aaattaacag tcttcgtgca
    21001 tcttactatt tttatgggag cctcttaggc cgttttggtg aagcgacagt tggtctaccg
    21061 ggaggatgtg atcttggtcc tcgtccgatt gacttacacc ttaaggcgtt tgaagctatg
    21121 ggtgccactg ctagctacga gggagataac atgaagttat ctgctaaaga tacaggactt
    21181 catggtgcaa gtatttacat ggatacggtt agtgtgggag caacgattaa tacgatgatt
    21241 gctgcggtta aagcaaatgg tcgtactatt attgaaaatg cagcccgtga acctgagatt
    21301 attgatgtag ctactctctt gaataatatg ggtgcccata tccgtggggc aggaactaat
    21361 atcatcatta ttgatggtgt tgaaagatta catgggacac gtcatcaggt gattccagac
    21421 cgcattgaag ctggaacata tatatcttta gctgctgcag ttggtaaagg aattcgtata
    21481 aataatgttc tttacgaaca cctggaaggg tttattgcta agttggaaga aatgggagtg
    21541 agaatgactg tatctgaaga cagcattttt gtcgaggaac agtctaattt gaaagcaatc
    21601 aatattaaga cagctcctta cccaggcttt gcaactgatt tgcaacaacc gcttacccct
    21661 cttttactaa gagcgaatgg tcgtggtaca attgtcgata cgatttacga aaaacgtgta
    21721 aatcatgttt ttgaactagc aaagatggat gcggatattt cgacaacaaa tggtcatatt
    21781 ttgtacacgg gtggacgtga tttacgtggg gccagtgtta aagcgaccga cttaagagct
    21841 ggggctgcac tagtcattgc tgggcttatg gctgaaggta aaactgaaat taccaatatc
    21901 gagtttatct tacgtggtta ttctgatatt atcgaaaaat tacgtaattt aggagcggat
    21961 attagacttg ttgaggatta aaccgtagag gtgtttatga atatttggac caaattagca
    22021 atgttttctt tttttgaaac ggatcgcttg tatttgcgtc ctttcttttt tagtgatagt
    22081 caggacttcc gcgagatagc ttcaaatcca gaaaatcttc aatttatttt cccaacgcag
    22141 gcaagtctgg aagaaagtca atatgcactg gccaattact ttatgaagtc ccctttggga
    22201 gtgtgggcaa tttgtgacca gaaaaatcaa caaatgattg gttctattaa atttgagaag
    22261 ttagatgaaa tcaaaaaaga agctgagctt ggctattttt tgagaaaaga tgcttggtcg
    22321 caaggattta tgacagaggt tgttagaaaa atttgtcagc tttcttttga ggaatttggc
    22381 ttaaaacaat tatctatcat tacccacctt gaaaatgaag ctagccaaag agttgctctt
    22441 aagtctggat ttagtttgtt ccgtcagttt aagggaagtg atcgttacac aagaaaaatg
    22501 cgggattatc ttgaatttcg gtatgtaaaa ggagagttca atgagtaagc atcaggaaat
    22561 tctaagctat ttggaggaat taccagtagg taaaagggtc agtgttcgta gcatttcgaa
    22621 tcatctagga gttagtgatg gaacagccta tcgggctatt aaagaagctg aaaaccgtgg
    22681 aattgtggag acccgtccta gaagtggaac aattcgtgtt aaatcccaga aagttgctat
    22741 agagagatta acgtttgctg aaattgcaga agtgacttct tctgaggttc tggctgggca
    22801 agaaggttta gagagagagt ttagtaagtt ttcaattggt gccatgactg aacaaaatat
    22861 cttgtcttac cttcatgatg gggggctctt gattgtcgga gaccgaaccc gtattcagtt
    22921 gctagccttg gaaaatgaaa atgcagttct ggttacaggg ggatttcagg ttcatgatga
    22981 tgtgcttaaa ctggccaatc aaaaagggat tcctgttcta agaagtaagc atgatacctt
    23041 taccgtcgcg accatgatca ataaagcctt gtcaaatgtc caaatcaaga ctgatattct
    23101 gacagttgag aaactttatc gccctagtca tgagtatggt tttctgagag agacagatac
    23161 agttaaagat tatttggact tggttcgtaa gaatcgtagc agccgtttcc ctgttatcaa
    23221 tcaacatcag gtcgttgttg gcgttgtaac catgagagac gctggtgata aatcaccaag
    23281 cacgacaatt gataaggtta tgtctcgtag tctatttttg gttgggttat cgacaaatat
    23341 tgccaatgtg agtcaacgga tgatcgcaga agactttgaa atggtaccag ttgttcgaag
    23401 caatcaaact ttgcttggcg ttgtgacgcg acgagatgtc atggagaaga tgagccgttc
    23461 ccaagtttcg gctctaccaa ctttttctga gcagattgga caaaagctct cttatcacca
    23521 tgatgaagta gtcattacag tggaaccctt tatgctagaa aaaaatggag ttttggctaa
    23581 tggtgtattg gcagaaattc tgacccacat gacccaagat ttagttgtta atagtggtcg
    23641 caatctcatt atcgagcaga tgctgatcta ctttttgcag gctgttcaga tagatgatat
    23701 attgcgcatt caggcacgga ttattcatca tacgagacgg tcagctataa ttgattacga
    23761 tatttatcat ggtcaccaga ttgtttcaaa agcaaatgtg actgttaaaa ttaattagaa
    23821 actaggagaa aagatgataa cattaaaatc agctcgtgaa atcgaagcta tggacaaggc
    23881 tggtgatttt ctagcaagta ttcatatagg cttacgtgat ttgattaagc caggcgtaga
    23941 tatgtgggaa gttgaagaat atgtccgccg tcgttgtaaa gaagaaaatt tccttccact
    24001 tcagattggg gttgacggtg ccatgatgga ctatccttat gctacctgtt gctctcttaa
    24061 cgatgaagtg gctcacgctt tccctcgtca ttatatcttg aaagatggtg atttgctcaa
    24121 agttgatatg gttttgggag gtcccattgc taaatctgac ctaaatgtct caaaattaaa
    24181 cttcaacaat gttgaacaaa tgaaaaaata cactcagagt tattctggtg gtttagcaga
    24241 ctcatgttgg gcttatgctg ttggtacacc gtccgaagaa gtcaaaaact tgatggatgt
    24301 aaccaaagaa gctatgtaca agggtattga gcaagctgtt gttggaaatc gtatcggtga
    24361 tatcggtgcg gctattcaag aatacgctga aagtcgtggt tacggtgtag tgcgtgattt
    24421 ggttggtcat ggtgttggcc caactatgca cgaagaacca atggttccta actatggtat
    24481 tgcaggtcgt ggactccgtc ttcgtgaagg aatggtctta accattgaac caatgatcaa
    24541 tacaggcgat tgggaaattg atacagatat gaaaactggt tgggcgcata agaccattga
    24601 cggtggattg tcatgtcagt atgaacacca atttgtcatt acgaaagatg gacctgttat
    24661 cttgactagc caaggtgaag aaggaactta ttaataaaaa gtgaaaagac tactggaagt
    24721 ttattttgat aaaaaatcca gtagatcttt tcataataaa acgcattgta tcaagtgtta
    24781 ggggctgata tcatgcgttt ttctgctttt aagatttttt ccaactctgt ttgtaagcgc
    24841 atcataacaa agggtctagg attcagggct ctcctcctat atactattag taaagtaaaa
    24901 ctaagggagg atattttagt gtcgcagtct attgttcctg tagagattcc acaatattgt
    24961 cgttttgatt ctaaaaagag aaatggaatt ctgtttaacg ttcgtattgc caatcttaaa
    25021 tttacctttt ttagattaga cttcctgcga aacaaaatat ggtatagtag ttccatgaat
    25081 tatgaagcaa gtaaacaact aactgatgca cgatttaaat gtcttgttgg tgttcagcgt
    25141 accacttttg aagagatgtt agctgtatta aaaacagctt atcaacttaa acacgcaaaa
    25201 ggtggacgaa aacctaaatt aagcctagaa gaccttctta tggccactct tcaatatgtg
    25261 cgagaatatc gaacttatga a
//
LOCUS       DAVLTT010000025        24214 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLTT010000025 DAVLTT010000000
VERSION     DAVLTT010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24214
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.025"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(24..3200)
                     /gene="carB"
                     /locus_tag="VYN15_001137"
     CDS             complement(24..3200)
                     /gene="carB"
                     /locus_tag="VYN15_001137"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV1452464.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(3513..4592)
                     /gene="carA"
                     /locus_tag="VYN15_001138"
     CDS             complement(3513..4592)
                     /gene="carA"
                     /locus_tag="VYN15_001138"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV1452465.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALAKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(4642..5565)
                     /locus_tag="VYN15_001139"
     CDS             complement(4642..5565)
                     /locus_tag="VYN15_001139"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV1452466.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(5584..6105)
                     /gene="pyrR"
                     /locus_tag="VYN15_001140"
     CDS             complement(5584..6105)
                     /gene="pyrR"
                     /locus_tag="VYN15_001140"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV1452467.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(6316..6945)
                     /gene="nth"
                     /locus_tag="VYN15_001141"
     CDS             complement(6316..6945)
                     /gene="nth"
                     /locus_tag="VYN15_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV1452468.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(6945..7487)
                     /locus_tag="VYN15_001142"
     CDS             complement(6945..7487)
                     /locus_tag="VYN15_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV1452469.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVGDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            7657..7974
                     /locus_tag="VYN15_001143"
     CDS             7657..7974
                     /locus_tag="VYN15_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1452470.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNNQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FEF"
     gene            8213..9772
                     /locus_tag="VYN15_001144"
     CDS             8213..9772
                     /locus_tag="VYN15_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1452471.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETTLRATKDSTAGR
                     LLSKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLAQELQLTVRGQEKIGIIGPNGIGKSTLLAKLQQLLNDKREISLGFMPQDYHK
                     KLQLDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(9921..10820)
                     /gene="htpX"
                     /locus_tag="VYN15_001145"
     CDS             complement(9921..10820)
                     /gene="htpX"
                     /locus_tag="VYN15_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV1452472.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALVSAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(10822..11382)
                     /locus_tag="VYN15_001146"
     CDS             complement(10822..11382)
                     /locus_tag="VYN15_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV1452473.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            11476..12189
                     /gene="rsmG"
                     /locus_tag="VYN15_001147"
     CDS             11476..12189
                     /gene="rsmG"
                     /locus_tag="VYN15_001147"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV1452474.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12492..13775
                     /locus_tag="VYN15_001148"
     CDS             12492..13775
                     /locus_tag="VYN15_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV1452475.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(13970..15541)
                     /gene="ffh"
                     /locus_tag="VYN15_001149"
     CDS             complement(13970..15541)
                     /gene="ffh"
                     /locus_tag="VYN15_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV1452476.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(15553..15885)
                     /locus_tag="VYN15_001150"
     CDS             complement(15553..15885)
                     /locus_tag="VYN15_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV1452477.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(15976..16353)
                     /locus_tag="VYN15_001151"
     CDS             complement(15976..16353)
                     /locus_tag="VYN15_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV1452478.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            16425..17729
                     /locus_tag="VYN15_001152"
     CDS             16425..17729
                     /locus_tag="VYN15_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1452479.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAVHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            17742..18548
                     /gene="yidA"
                     /locus_tag="VYN15_001153"
     CDS             17742..18548
                     /gene="yidA"
                     /locus_tag="VYN15_001153"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV1452480.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDEGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(18603..18674)
                     /locus_tag="VYN15_001154"
     tRNA            complement(18603..18674)
                     /locus_tag="VYN15_001154"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18639..18641),aa:Arg,seq:cct)
     gene            complement(18716..19063)
                     /gene="rplS"
                     /locus_tag="VYN15_001155"
     CDS             complement(18716..19063)
                     /gene="rplS"
                     /locus_tag="VYN15_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV1452481.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(19182..19511)
                     /gene="crcB"
                     /locus_tag="VYN15_001156"
     CDS             complement(19182..19511)
                     /gene="crcB"
                     /locus_tag="VYN15_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1452482.1"
                     /translation="MVIVYLAIACGFGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLILTYLGGLVA
                     IFLGILL"
     gene            complement(19505..19879)
                     /gene="crcB"
                     /locus_tag="VYN15_001157"
     CDS             complement(19505..19879)
                     /gene="crcB"
                     /locus_tag="VYN15_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1452483.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(19876..20142)
                     /locus_tag="VYN15_001158"
     CDS             complement(19876..20142)
                     /locus_tag="VYN15_001158"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV1452484.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(20258..20701)
                     /locus_tag="VYN15_001159"
     CDS             complement(20258..20701)
                     /locus_tag="VYN15_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV1452485.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            20805..21740
                     /locus_tag="VYN15_001160"
     CDS             20805..21740
                     /locus_tag="VYN15_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV1452486.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            21794..22078
                     /locus_tag="VYN15_001161"
     CDS             21794..22078
                     /locus_tag="VYN15_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV1452487.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(22135..22713)
                     /locus_tag="VYN15_001162"
     CDS             complement(22135..22713)
                     /locus_tag="VYN15_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEV1452488.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKT
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSTAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(22688..23701)
                     /gene="efeB"
                     /locus_tag="VYN15_001163"
                     /pseudo
     CDS             complement(22688..23701)
                     /gene="efeB"
                     /locus_tag="VYN15_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
     gene            complement(23704..24163)
                     /locus_tag="VYN15_001164"
                     /pseudo
     CDS             complement(23704..24163)
                     /locus_tag="VYN15_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT         7127 a         5458 c         4613 g         7016 t
ORIGIN      
        1 tctgctatat cttatttttc tatttaaatc gcttctgtaa caaagctacg actttcaagt
       61 accttaagca tggcattagc tgtatctagc gctgtgaaga ggggcacccc gtgttcaatg
      121 gctgaacgac gaatttgctc accatcttcg tcagcagttc gttttgttcc tactgtgtta
      181 atgatagctt gaattcttcc tttgcgtaca aaacttggga tatccttatc gtcatcacca
      241 atcttaccaa caggttgggc ttgcaagcca tggctagcaa agaaggctgc tgtcccttct
      301 gtcgcaagga ttccataacc aatgttttgg aaacgacgag ccaagttcaa ggcttcttct
      361 ttggcatcat cagcgatggt aaagacgaca ttaccaaaag ttggcaagtg tagataagaa
      421 gcttcaaagg ctttatagag agctttttcc aaagtagcat cagaacccat aacttcacct
      481 gttgacttca tttcaggacc gagcaagctg tctaccttag ctagtttggt aaaggagaag
      541 acaggtgcct tgatatgaac acgggtgctt tcagggtaaa gtccattttg gtagccaagt
      601 tctgataaac tttgaccaag aatgagcttg gtcgctactt gagccatagg aatattggtt
      661 accttagata ggaatggaac agtacggctg gcacgtggat tgacctcaat aacgtagact
      721 ttttcatcct tgataacaaa ctggatgttc atcattccaa ggcagtgaag accgattgct
      781 aagcgtttgg tgtagtctgc gatggtctcc tgaacctttt gcgacaaggt ttgtggtggg
      841 taaacagcca ttgagtcacc tgagtggaca ccagcacgtt cgatatgctc catgatacca
      901 ggaatgagca catctttacc atctgaaatg gcatcaactt cgcactcttg cccaacgata
      961 taagagtcga caagaactgg gtgatctgga ctagccttaa cagcagttcg catgtaagaa
     1021 cgaaggtctt cttcgttttc aacgatttcc atggcacgtc caccaagtac ataagatggg
     1081 cggacaagaa ctgggaagcc aatcttacga gctgcaagag ctgcttcttc ttcattggta
     1141 gccgtttgtc ctggtggctg tggaatatcc aattctttga gagcttgctc gaagaggtca
     1201 cggtcttcgg cacggtctag gtcagcaacc tgtgtaccaa ggatggtcac acctgctttt
     1261 gccaatggct ccgcaaggtt gatggctgtt tgaccaccaa actgaacgat aactcccttt
     1321 ggttgttcca agtcaatgac gttcataaca tcttcgaatg tcaatggctc aaagtaaagc
     1381 ttatctgata cagagaagtc tgttgaaacg gtctctgggt ttgagttcat gatgatagct
     1441 tcataaccag ctgcctggat agccttaaca gagtgaacgg ttgcgtagtc aaactcaacc
     1501 ccttgaccga tacggattgg acctgaacct aggacaagta cagattcttt atcagatctg
     1561 atagattcat tttcccaacc ataggttgaa tagaaatatg gcgtttcaga gtcgaactct
     1621 gccgcacaag tatctaccat cttataaact ggaacaatct tgttttccaa gcgaagttgg
     1681 cgaacttgat catcagtcgt tccccagagt tcagcaatct tacggtctga gaaaccatta
     1741 agtttggctg ttttcaaaac ttctagatct tgtggatgag cacccaattc ttgctcaatt
     1801 tcaaagatat gcaagagttt atcaagatag aagatatcaa tttttgtaag ctctgcaatt
     1861 tcttcaggtg tgtagccacg acgaatggct tctgatacgt agaagagacg gtcatcttgg
     1921 gctttgacaa ccttttcaat caaggcatca tcagaaactg ctgcaagttc aggtatttca
     1981 ttgtggtgca ccccaatttc aagggagcgg caggccttga gaagagattc ctcgatgtta
     2041 cgaccgattg ccatgacttc tccagtcgcc ttcatttgtg taccgagacg gcgttcaccc
     2101 ttttcaaact tgtcaaatgg gaaacgtgga atcttagcaa ctacgtagtc aagggctggt
     2161 tcaaacatgg cataggttga acctgtaact gggtttataa cctcatccaa ggtcaaacct
     2221 actgcaatct tggcagccaa cttagcaatc ggatatcctg tcgctttaga agcaagggct
     2281 gacgaacgtg atacacgagg gtttacttcg ataacataat acttgaagct gttaggatca
     2341 agagctagct gaacattaca tccaccttca atcttgaggg cgcgaataat gctcaagctc
     2401 gcatcacgaa gcatttggtt ttcatagtct gacatggttt gcgcaggggc aaatacaatg
     2461 gaatcccctg tgtgaatccc aactgggtca aagttttcca tgttacaaac aaccaaggca
     2521 ttgtcagctg agtcacgcat cacttcgtat tcaatttcct tgaaaccggc aatcgaacgc
     2581 tcaatcaaac attgggtaac aggtgacaat ttcaaaccat tttcagtgat ttcacgcaat
     2641 tctttttcgt tggcacacat accaccacca gtaccaccaa gggtaaaggc tggacgaacg
     2701 atgactgggt agccaattgt cgctgcaaag gcaactgctt cttctactgt gttaacaatt
     2761 tcagattctg gaatgggttg ctcaagctct tccatcaatt gtttaaagag gtcacggtcc
     2821 tccgcttggt caatggcaga caatttagta ccgagaagct ctacaccaag ctcatctaag
     2881 atgccatttt tagacaattc catggccatg ttgagacctg tctgaccacc gagtgttggt
     2941 agcaaggcat ctggacgttc cttacgaaga atacgtgtca caaactcaag tgtaatcggt
     3001 tcaatgtaaa ccttgtcagc aatttccttg tccgtcatga tggttgcagg atttgagtta
     3061 accaaaacaa cctcataacc ttcctctttc aacgacaagc aagcctgggt cccagcgtag
     3121 tcaaactcag cagcctgacc aataataatc ggaccagaac caatcaccat aattttttga
     3181 atatcagtac gtttaggcat atataagata ttaagggcgt caagcggaca aagctaaaat
     3241 aggagttatg acgaagaact gtcagttcta ggaataacta tctttttagc accgtccgta
     3301 gcccgtattc agttcagcaa atacggagca cccttctcct ttctattcgt cgcctctcag
     3361 ggcgacatta aataagatac aaaggacgaa tagaaagcga ttgaatttta agaaatcaag
     3421 gaaggattga caatccaagt tggtttctct aaattctgag ctttccgtcc gtgttcagtt
     3481 acataaattc tccgacgagc ttttactcgt tcttagtttg attgtttaaa aacttccatc
     3541 atctcgataa actcgtcaaa taggtagcta gcgtcgtgtg gcccaggagc tgcatctggg
     3601 tggtattgaa cagagaaagc aggttggtat ctgtggcgca caccttccac tgacttgtca
     3661 ttgatttctt cgtgggtaat aatcaagtgc tctggcaaat cctcgcggct gactgcataa
     3721 ccatggttct ggctggtgaa gtctactcgt cctgttgcga tttcacgtac cgcatggttg
     3781 aatccacggt ggccaaactt catcttatag gtcttagccc cgtttgccat tgcaaagagt
     3841 tggtgtccca tacaaatacc aaagattgga atttttcctt gtacaccgcg aatcatgtcg
     3901 agtgcttgtg gaacgtcttc tgggttacct ggaccatttg acaacataac tccatcagga
     3961 ttgagatgga gaatttcttc agccgttgtc gaataaggaa caactgtcac gttacagttg
     4021 cgtttagaaa gttcacgtag gattgagtgc ttgagaccaa agtccactag caccacgctc
     4081 aaaccaactc ctggagctgg ataagacgtt ttagtagaaa cctgtttgat attgtctgtc
     4141 ggtaaaactg ttgcttggag ctggtccgtc acatggtcca tactgtcccc aacatgggtc
     4201 aaggttgcac gcatagtacc atgcttacgg ataatcttgg caagagcacg cgtatcaatt
     4261 cctgaaatcc ctggaatttt cttggctttc aaaaattcat ccaaggtcat ttggttgcgc
     4321 cagttgctag ctctacgcgc ttcttcaaaa acaacgactc ccttacaagt tggaataatg
     4381 gattcataat catcacgatt aataccataa tttcctacca aaggataagt aaaggtcaag
     4441 atttgtccat tataagactg gtctgtaatg gattcttggt agccggtcat ccctgtatta
     4501 aagacgattt cgcctgttac atcaatatct gctccgaagg ccttgccttc aaaaactgtg
     4561 ccatcttcta atactagaat tctttttgtc atattttcac ctctcgtgga cgctcactgg
     4621 cgtcttttaa cgtcttgtgt tttagttggc gtttctactc gctagtacgg attctaagat
     4681 tgccattcga acaaagacac cattggtcat ttgttggaca atccgtgatt ttggtgcttc
     4741 aaccaagtgg tctgctattt ctacatcacg attgattgga gctgggtgca tgaggattgc
     4801 tgtttctttc aaacgatcgt aacgttcttg agtcaagcca tgttgggcat ggtagtcttc
     4861 ttttgaaaat acagctccac tatcatggcg ttcgtgttgc acacggagaa acatcatgac
     4921 atcaacctga tcaatgattt catcaatggt tacaaacttt ccatagtctg caaactcttg
     4981 acttctccat tcctcaggtc cagcgaaaaa gagttcagct cccaagcgtt tcaaaatctg
     5041 catattggat ttggcaacgc gtgagtggtc caagtcacct gcaatagcaa ctttaagacc
     5101 ctcaaagtgg ccaaattcct cataaatggt catcaaatca agcaagctct ggctagggtg
     5161 ttggcccgaa ccatctccac cattgatgat ggaagtcgta atcgttggac tagcaatcaa
     5221 ttctctatag tagtcgacct ctggatggcg aatcacacag acatccactc ctaaagcaga
     5281 cagagtcaaa atggtgtcat aaagtgtctc acccttatta accgaactag tcttcacatc
     5341 aaagtcaagt cgttccaatc caagtttaat ctctgcgact tcaaaggact tatgtgtccg
     5401 tgtagaatcc tcaaagaaga gattggaaac aatcggatgg tcttcatagg gaagctgggc
     5461 tccattttta aactcaattc ctcgcttgat caatttcatt acttgatcga cagtgaggtc
     5521 ttccatggac accacatggt tcaatgcttg ttgattttct gacatggcta ctcctttaac
     5581 tttctaagct tcttcagtaa tcagaactct gtcttggtca tcaagttctg tcatctctac
     5641 gatgatttct tcagaacgac tggttgggat attttttcca acgtaatctg gacggattgg
     5701 caattctcta tgtccacgat cgactagaac tgctaaactc acacgcgcag gacgaccatg
     5761 accgacaata ttatcaatag cagcacggat ggtacgacct gtatagagca catcatccac
     5821 caagataact tcgcggtctg tcacatcgac agaaaccaaa gaagtatctt ctccactttt
     5881 aacatcatca cggaaaggtt tagtatccaa ttccacaaca ggaactgaaa gattttctaa
     5941 ctgcttcaaa cgttcttgga ttcggtgggc aataaagaca ccacgagttt taataccagc
     6001 caagacgatc ttattcaaat ctttgttgcg ttcgataatc tcataagtaa tacgcgtaat
     6061 cgctcgtttg acggtcaatt cgtctacaac ttcttttgtt ttcatgacaa acctccaaaa
     6121 agaaaagtct ccttaaacaa ggagacttga aatttatagc caagcgagcc ctactgcaca
     6181 cagtatagac ttcacccttc tactttatcg cgctccttgc ctgcctcacg ggacaggttt
     6241 aaaggaatat ttagttatca tttactatag cacaaagcat gcttaaaatc aagcaaaaag
     6301 tttcaatgta gcatcttaca aattgctaaa atcatataat tgtgggtact ggtcacactc
     6361 tggatttttt ggatggcaaa tggctcttcc aaaataaatc atggcctgat gggcagctaa
     6421 ccactgctca ggcggcaaga tatccatgac ccgcttttcc acctcaagtg gcgtcgctga
     6481 ttttttgaca atatcgtggt gtttgcaaat acgctccaca tgagtatcca ctgcaaaggc
     6541 tggaatccca aatcctacac tcatgacaac attggctgtc ttgcgaccaa cacctgccaa
     6601 actctccaat tcttcacgtg tctgagggac ttgaccatca aaatcgtcta gtaactgttg
     6661 ggcacatttt ttaaggaatt tagctttatt ccgatacaat cccaagcgag aaatatgtga
     6721 agcaatctca ctctctgtcg ctacagacat agcttggggt gttggaaagg caacaaagag
     6781 acctggtgtg gccttattta ccgctgcatc tgtcgtctgg gctgataaca tgaccgcaac
     6841 caggagttca aaatgattgg taaaatcaag actaggcttg gcatctggga agagggcaat
     6901 gatttcttct agcacctttc gtgctcgttt ttttgacaag accattattc atctccgtca
     6961 aatagtcctt gtaagccagc aaaaggactg ttttcttctt tctttactgc tttttgagct
     7021 tggtattctt cctctgtcat gatttgccag tcatttcctg agataaatcc ttgaccagct
     7081 tcttcttcag ccgtcaagac cttgatagga atgtttagca ggatattgtc tgatacactc
     7141 tcagcaaggt caagctcccc attttcgatg ggcaagacca agtcatcatc taaaacttct
     7201 tgatctagct ggttagttgc gccttccatg aaaacttccg tgactggata agattcaact
     7261 aactcaactg gctccatact gcgactcgaa gcaagaacaa tggtataaga tagttgataa
     7321 tctaagaaat acatacggtc ttcatattgt actttcccaa ctgcaaggat atcttttaca
     7381 tctaaaattt cttgattacg tgcacgcagg tcaccaacta aatctaacgt ttgttcaaag
     7441 ttcaaacctt cagactgctt acgaatttct tgaatattta atttcatact tcctccataa
     7501 agatttactc tcttgattat accatgaaaa ggctacaaat cagcacacca aactttgtaa
     7561 ttaaaattca aaattttaac atatttacta tgacagtttt gttttttagt gctatactat
     7621 agggaaagag tacatcagat caaggaggat gctcacatgg aagacaagaa actcattcaa
     7681 ctcctatcca agttaaataa aagctaccaa aactgtaaac agggtacggc agatgatatt
     7741 cgactacaag agctgctaaa cactactatg caagagctca aaaaaacgga aaagttgaac
     7801 aacagtatct taattgatct tgagaaattt taccaaccca ccagtcctct gattggactg
     7861 ggtagcctaa aactaaacaa tcaagcacgc actgcttggc gaaactatga taaattccat
     7921 tacgagcatg tcaaacacgt actaagtctc tatggacctg tttttgaatt ttagagcata
     7981 gaatttccag ttttctgttg acaaaatttc cttaaaggta taatataaag atactaatac
     8041 tcggaggtaa gggagacatg aacaactaag tctatcaaat aaagaacctt tatttagtag
     8101 atcttgtttt tgtctctttt tgtgtgctct tttatgctct ttttctggca tgttaataga
     8161 gtttttttga catagacttt gggctctact aggtaaagta gagctttttg ttatgcacta
     8221 tgaacattct agaaagggaa atcatatgat aaaaatcaat catctaacca tcacacaaaa
     8281 caaagattta cgagatcttg tatctgacct aaccatgacc atccaagacg gggaaaaggt
     8341 tgctattatt ggtgaagaag gaaatggcaa atcaacctta cttaaaattt taatggggga
     8401 agctttgtct gatttcacta tcaagggaaa catccaatct gactatcagt cactggccta
     8461 cattcctcaa aaacttcccg aggagctgaa aaagaaaact ttacacgact acttcttttt
     8521 agattctatt gatttagact acagtatcct ctatcgtttg gcggaggaat tgcattttga
     8581 tagcaatcgt ttcgcaagtg accaagagat tggcaatcta tcagggggag aagctttgaa
     8641 aattcagctt atccatgagt tagccaaacc ctttgagatt ctatttttag atgaaccttc
     8701 aaatgaccta gaccttgaga cagttgattg gctaaaaggc cagattcaaa agaccaggca
     8761 aaccgttatt ttcatttccc atgatgaaga ctttctttct gaaacggcag acactattgt
     8821 tcacttgcga ctggtcaaac accgtaaaga agcggaaacg ctagtagagc atttagacta
     8881 tgatagctat agtgagcaga gaaaggctaa ttttgccaaa caaagtcagc aagctgctaa
     8941 caaccaaaga gcctacgata aaaccatgga aaaacatcgg agagttaagc aaaatgtaga
     9001 aactacgctt cgagctacca aagatagtac tgccggtcgc ctattgtcta aaaagatgaa
     9061 aactgtcctc tcacaagaaa aacgctacga aaaggcagct cagtccatga ctcaaaaacc
     9121 acttgaagag gaacaaatcc aacttttctt ttcagacatc caaccattac cagcttctaa
     9181 agtcttagtc caactggaaa aagaaaattt gtccattgac gaccgtgttt tggctcagga
     9241 actgcaacta actgtccgtg gccaagaaaa aatcggtatc atcggcccaa atggtattgg
     9301 gaaatcaact ctgttagcca aattacagca acttcttaat gataaaagag agatttcact
     9361 tggttttatg ccacaagatt accacaaaaa actgcaattg gatttatcct caatagctta
     9421 tatcagcaaa actggggaaa aagaggaact tcagaaaatc caatctcacc tagccagtct
     9481 caatttcagt tatccagaaa tgcagcatca aattcgctcc ttatctggcg gacaacaggg
     9541 aaaactcctg cttttggatt tagtcctgcg caaaccaaac tttctcctgc tggatgaacc
     9601 cacacgaaac ttttctccca cttctcaacc ccaaatcaga aaactctttg caacctatcc
     9661 aggcggtctc atcactgttt cgcatgaccg tcgtttctta aaagaagtct gctcgatcat
     9721 ctatcgcatg acagaacacg gtttgaagct agttaattta gaagatttat aaatttgcaa
     9781 catagcagat aggtggggca aaaacacaat tttaggagaa aaagaagtaa atcttcccat
     9841 agtaaaacgc ataatatcaa gttttcacac ctgatattat gcgtttttca gattttaaag
     9901 acttttttcc agccttcatt ttacatctgt tttaaacgtt caatccgttc tgagataggt
     9961 gggtgggtat aaaagagttt ttggaacccc ccacctttct tgggatcatt gatataaaga
    10021 gcactgctag catcatcgac gtggcgactc ataggtttgc tattgtccaa cttatctagg
    10081 gcattaatca ttccctgggg attgcgagtc agctcgacac tagatgcatc tgccagaaat
    10141 tccctctgac gagaaatagc gagctgaacc aaggttgcag cgagaggtgc cagtacaata
    10201 gctagtaggg aaaccactag cataatgatt tcaagaccat ttccatctcg gtcatcatca
    10261 cttcgtctgc gacctgctcc accccaccac atcatacgac ctgccatacc agaaagcatg
    10321 gtgatagcac taacaagggc aactgcaata gtcgaaatac ggatatcata attacgaata
    10381 tgactgactt catgtcccat aacagcttct agttcttcac gattcatgat agctagtaga
    10441 cctgaagtcg cagcaacagc cgcattttga ggattagaac ctgtcgcaaa ggcatttaag
    10501 gctggatcat caatgatgaa aacacggggc ataggaatct gagcgaccag agccatatct
    10561 tccactacat ggtagaggtc tggtgccgtt tgctcatcca cctcacgcgc tccattcatg
    10621 gacatgacaa tctctgtcga ttgaaaaatc atagacaaag cgtagataaa gccgataatc
    10681 agtgcgataa ccaaaccacc aagtccagat cttataaaga gataaccaac cgcataacca
    10741 acaagagcta agagtaggaa aaataccagc aacaaaatcc aggtttttcg tttattgctt
    10801 gcaatttgat caaacaacat cttagtcacc taaaccgcta aaatcaactt taggaaccga
    10861 cttttcctct tcaggtgttt gaaggaaatc tgccgcttta aatccaaaca ttccagcgat
    10921 aatattgctc gggaaagttt ctaattttac attgtagttg ctgacaacac tgttatagag
    10981 ttgacgagag taagaaattt tattttctgt gtttgtcaac tcctcttgca atttaacaaa
    11041 gttagcacta gctttcaaat ctggatagct ttctgcaact gcaaaaatac ctgaaacctg
    11101 acgagtgagg gcatcactgg ctttcatagc ttctgctggt gaagtcgctg ccgccacttg
    11161 gttacgtagt tctgccacct tttcaagggt agaaccttca tatttggcat aaccttttac
    11221 agtctcaatc aagtttggca agagatcatt gcgacgtttc aactgaacat caatctgact
    11281 ccaagcctcc ttggtttgca tacgattttt aaccaaaccg ttatagctaa caatcacaaa
    11341 aataacaata agagcgataa ctccaagaat aatccaagtc atgatataag tcctttctac
    11401 ttttagatta gtaccagtat atcaaatttt taatgattgt ggtaaaataa gatgatacta
    11461 aagaaggaaa taactatgaa accagaaaca ttttacaact tgcttgccga gcagaatctt
    11521 ccactttcga accagcaaaa agaacaattt gaacgttatt ttgagctctt ggtcgagtgg
    11581 aatgagaaga ttaatttgac ggcgattacg gacaaggaag aagtttatct caaacatttt
    11641 tacgattcga ttgcacccat tcttcaaggt ttgattccca atgaaactat caaacttctt
    11701 gatatcgggg ctggggcagg atttcctagt ctaccaatga aaattctcta tccggagtta
    11761 gatgtgacca ttattgattc actcaataag cgcatcaact tcctacaact cttggctcaa
    11821 gaactggatt tgaacggagt tcatttctac cacggacgtg ccgaagattt tgcccaagac
    11881 aagaacttcc gtgctcaata tgattttgta acagctcgtg cggttgcccg tatgcaggtc
    11941 ctatctgaat tgactattcc ctaccttaag gttggtggaa aactattggc actcaaggcc
    12001 agcaatgcgc ctgaggagtt gttagaagct aagaatgccc tcaatctcct ttttagtaaa
    12061 gtcgaagaca atctcagcta cgccctacca aatagagatc cgcgttacat cacagtggta
    12121 gaaaagaaaa aagaaacacc aaataaatat ccacgtaagg ctggtatgcc aaataaacgc
    12181 ccgctttaaa tttttaagta aaaaaatatt tacaaaatca acctcgctct cttattttta
    12241 ggctcgggaa aaaatgattt acaaaatcag cctcgctctt ttatttctag gctcgggaaa
    12301 aaatgattta caaaatcatt tttttctgct atactatcct aagcaaaggt ttttaatgtc
    12361 atcccgtgag gtgacgaaga cgcagaaata tttaaaactc tttaaaatct aaattttaaa
    12421 gaagtcttac tctgagggcc tattgctgta aaataatggg ctcttttttg atgcccaaaa
    12481 gtgaggttta tatgaaacaa gaatcaactg ttgatttgtt attagacgtt gaccaacgtc
    12541 cttcggctgg aaaaggaatt ctccttagct tccaacacgt tttcgccatg tttggtgcga
    12601 ccatcttggt accattgatt ttgggaatgc ctgtatctgt tgcccttttt gcttcaggtg
    12661 ttggaacact catctacatg attgctactg gttttaaagt tccagtttat ctaggttctt
    12721 catttgcctt tatcacagct atgtcactgg ctatgaaaga aatggggggt gatgtatctg
    12781 ctgcccaaac aggggttatc ttgactggtt tagtctatgt ccttgttgct accagcatcc
    12841 gatttgtagg aacaaaatgg attgataaac tcttgccacc aatcattatc ggtcctatga
    12901 tcatcgttat cggtcttgga cttgcaggtt cagctgttac caatgcaggt cttgtagcag
    12961 acggaaattg gaaaaatgct ctggtagccg ttgttacttt cctaattgct gcctttatca
    13021 atacaaaagg aaaaggcttc ctacgaatca ttccattcct ctttgccatt atcggtggtt
    13081 accttttcgc actaactctt ggcttggttg actttacacc agttcttaaa gccaactggt
    13141 tcgaaattcc tggtttctac ttgccattta gcacaggtgg tgcctttaaa gagtacaatc
    13201 tttactttgg tccagaagcc atcgctatct tgccaatcgc tatcgtaaca atttctgaac
    13261 atatcggaga ccatactgtt ttgggtcaaa tctgtggccg tcaattctta aaagaaccag
    13321 gtcttcaccg tactcttctt ggtgacggta tcgcaacttc tgtttctgcc ttccttggtg
    13381 gaccagccaa tacaacttac ggagaaaata caggggttat cggtatgact cgtatcgctt
    13441 ctgtctcagt tatccgtaac gctgccttca tcgcgattgc cctcagcttc cttggtaaat
    13501 tcactgcctt gatttcaact attccaaacg ctgtacttgg tggtatgtca atccttctct
    13561 atggggttat cgccagcaat ggtttgaaag tcttgattaa agaacgtgtt gatttcgctc
    13621 aaatgcgaaa cctcatcatc gcaagtgcta tgttggttct tggacttgga ggagctatcc
    13681 ttaaacttgg tccagttaca ctttcaggta ctgccctttc agccatgaca ggaatcatct
    13741 tgaacttgat cttgccatac gaaaataaag actaagagtc taaatacacc taatccactc
    13801 agacagctga gtggattttt cgtatattat aataaaagtg tcttaacaaa attattaaaa
    13861 tcaaaaaacg tataatatca gatattctaa aaccttgata ctgtacgttt tatcatagaa
    13921 atttttactt tattttctca tcaaatgaga tttgcatcaa tctcttgtct tacttgcgtt
    13981 tcttcttcgc tttcttcatt ttgttagcca tacgtttcat ggactgtttc atggcaaatt
    14041 caccaatttt acctttcaaa ccgccaccaa acatctggct catatctggc attcctgctc
    14101 ctccgagagc tgataagtca ggcataccgc cttgtcccat cattccttca agggcagaca
    14161 tatccattcc tcccatattt ggcatatttt taggaaggtt atttggatta atccccattt
    14221 gcttcatcat tttattcata tccccagaca taacaccctg catgagctgt ttagcctggt
    14281 taaagtcctt gatgaattta ttgacttcga cgaatgtatt tccagaacca gcagcaatac
    14341 gacggcgacg gcttggattt aacaaatctg ggttttcacg ttcttcaggt gtcatcgaag
    14401 acacaatcgc acgtttacga gcaatctggc gttcatccac cttcatgttt tgaagggctg
    14461 gattgttggc catacctgga atcatcttga gcaagtcttc catcggcccc atattttgca
    14521 cctgatctaa ttgatcgatg aaatcattaa aatcaaaggt gttttcgcgc atcttctcag
    14581 ccatttcaag ggctttttgt tcatcgtatt cctgagaagc tttctcaatc aaagtgagca
    14641 tatcccccat accaaggata cggctagaca tgcggtctgg gtggaaggtt tcaatgtccg
    14701 taatcttttc acctgtacca gtgaacttga ttggttttcc agtaatgtga cgaacagaca
    14761 gagcagcacc accacgagta tcgccatcaa tcttggtaag gatgacccca gtcacttcca
    14821 actgagcatt aaactcacgc gcaacattgg ctgcttcctg accaatcata gcatcaacga
    14881 caagcaagat ttcatttggt tgagccaatg ctttcacatc acgaagctca ttcatgagga
    14941 gctcatcaat ctgcaaacga cccgcagtat caatcaagac atagtcgtta tgattagttt
    15001 gggcttgctc caaaccttga cgtacaatct caacagctgg tacttctgtt ccaagtgcaa
    15061 agacaggcac atcaatctgt tgtcccaagg tcttaagctg gtcaatggca gctggacgat
    15121 aaatatccgc cgcaatcatc aaaggacgag cattttcttc tttcttgagt ttgttggcca
    15181 atttaccagc aaaggttgtt ttaccagccc cttgtaaacc aaccatcatg atgatggttg
    15241 gaatcttagg tgacttgata atttctgccg tatcagaacc taaaacggct gtcagttcct
    15301 catcaacgat tttaataatc tgttgcgcag gattaagtgt atcaatgacc tcatgcccga
    15361 ctgcacgctc acgaactttc ttgataaagt cctttacaac aggcaaggca acgtcggcct
    15421 cgagcaaggc caagcgaatt tctttggttg cctcttggac atcagattca gagatttttc
    15481 cttttttacg tagattttta aagacgttct gcaaacgttc tgttaaactt tcaaatgcca
    15541 tttttcttcc tcttattctc tattatcaat gcttgttaaa atttctatct gctcctgcag
    15601 aaagtcatcc ttgggatagc gctccaaaat ctgatcaaaa atctgactgc ggacaatata
    15661 gtccgagtac atgtgcaatt tcatctcata atcttccaga atcttttctg ttcgcttgat
    15721 attgtcatag acagcctgac gactgacacc gaactcctcg gcaatttcag caaggctgta
    15781 atcatcagcg tagtagagct cgatataatt catttgctta tctgtcaaaa gcgccgcata
    15841 aaattcaaag agcgcattca tacgattggt tttttcgatt tccataactt ttattatacc
    15901 aaaaattagc ctaatctacc acactaggaa gccgatccaa gaagatagat agctaaattt
    15961 gaaaaagaca tgagcctagc cccaagtaat ttccaattga tagctggcaa agggatgtcc
    16021 ctcttgattt tgtagttgat aatctagttc aatcttttgc ctatcaactt gataatggct
    16081 cgtttggatg ataaactcct gcatgcccat aggtgtagga atataggcta aactatcgct
    16141 atcctttaga aagcgcataa tggtcttggg attagaaaat cggctcatca caagttcttg
    16201 accatgaaat ttaatcacta ctttttcctt ttcctcatta tagaaaagca ggtagctata
    16261 atctcctttt tcatgcactt ccacatcata aagctggtca atcacttcca actgctcatc
    16321 aaactgaatc gtatttcgca tccgaatctt cacatcaggc cctctttctt gtctcttgtc
    16381 ctactatttt accaaaaaga gcaggatttt gctataatgg tcatatgaac gaaaaagtat
    16441 tccgtgaccc tgttcacaac tacatccatg tcaataatca aatcatctat gacttgatta
    16501 atacaaaaga atttcagcgt ttgcgccgga tcaaacaact gggaacttcc agttatacct
    16561 tccacggtgg agaacacagt cgcttctctc actgtctagg agtctatgaa attgcacgac
    16621 gcatcacaga gattttcgaa gaaaaatatc ctgaggaatg gaatcctgcc gagtctctct
    16681 tgaccatgac cgctgctctc ctacacgacc ttgggcatgg tgcctactcc catacttttg
    16741 aacatctctt tgatacagac catgaagcca ttactcagga gattattcaa aatcctgaga
    16801 cagagattca ccaagtcctg ctacaagtgg cacctgattt cccagaaaag gtggccagtg
    16861 tcattgacca tacctatcct aataagcagg tcgtgcagct catttctagt cagattgacg
    16921 cagatcgcat ggactatctc ttgcgcgact cctattttac aggagcatcc tatggggaat
    16981 ttgacctgac tcgaatcctc cgagtcattc gtcctatcga aaatggtatc gcctttcagc
    17041 gcaatggcat gcacgccatc gaagactacg tcctcagtcg ctaccagatg tacatgcagg
    17101 tttatttcca ccccgcaaca cgcgccatgg aagttctcct acagaatctt ctcaaacgcg
    17161 ccaaggaact ctatcctgag gacaaggatt tctttgcccg aacttctcca cacctcctgc
    17221 ctttcttcga aaaaaatgtg accttgactg actatctggc tctggatgat ggcgtgatga
    17281 atacctactt ccagctttgg atgaccagtc ctgacaagat tcttgcagat ttatcgcatc
    17341 gctttgtcaa ccgcaaggtc tttaaatcca ttaccttttc acaagaggac caagatcaac
    17401 ttactagcat gagaaaattg gttgaggata tcggctttga tcccgactac tacactgccg
    17461 ttcataagaa ctttgacctc ccttatgata tctatcgtcc cgaatctgaa aacccacgga
    17521 cacagattga gattttacaa aaaaatggag aactggccga actctctagc ctgtctccta
    17581 tcgtccaatc ccttgctggc agtcgccacg gagataatcg cttttatttt ccaaaagaaa
    17641 tgttggacca aaacagcatc tttgcaagca ttacccagca atttttacac ttgattgaga
    17701 acgatcattt taccccaaat aaaaactaga agaggaaatt tatgagtatt aaactaattg
    17761 ccgttgatat cgacggaacc cttgtcaaca gccaaaagga aatcactcct gaagtttttt
    17821 ctgccatcca agatgccaaa gaagctggtg tcaaagtcgt gattgcaact ggccgcccta
    17881 tcgcaggcgt tgccaaactt ctagacgact tgcagttgag agacgagggg gactatgtgg
    17941 taaccttcaa cggtgccctt gtccaagaaa ctgctacagg acatgagatt atcagcgaat
    18001 ccttgactta tgaggattat ctagatatgg aattcctcag tcgcaagctc ggtgtccaca
    18061 tgcatgccat taccaaggac ggtatctata ctgcaaatcg caatatcgga aaatacactg
    18121 tacacgaatc aaccctcgtc agcatgccta tcttctaccg tacccctgaa gaaatggctg
    18181 gcaaagaaat tgttaaatgt atgtttatcg atgaaccaga aattctcgat gctgcgattg
    18241 aaaaaattcc agcagaattt tacgagcgct actccatcaa caaatctgct cctttctacc
    18301 tcgaactcct tacaaagaat gtagacaagg gttcagccat tactcacttg gctgaaaaac
    18361 tcggattgac caaagatgaa accatggcaa tcggtgacga agaaaatgac cgtgccatgc
    18421 tggaagtcgt tggaaacccc gttgtcatgg aaaatggaaa tccagaaatc aaaaaaatcg
    18481 ccaaatacat cactaaaaca aatgacgaat ccggcgttgc ccacgccatc cgaacatggg
    18541 tactgtaaaa ggaaagaata gactaaaacc gctcagctga gcggtttttg atgtctaatt
    18601 actgccccct gcaggaatcg aacctgcaac tactccttag gagggagttg ttatatccat
    18661 tgaactaagg gagctagata aaaactctgc tgaaaagcag agttttttag tcgaattaac
    18721 gacggatttc tttgatacga gctgctttac cttgaagagc acgcaagtag tacaatttcg
    18781 cacgacgtac tttaccgtaa cgaacaactt cgattttttc aacacgtgga gtgtggattg
    18841 ggaagatacg ctcaacacct acaccgttag agattttacg aactgtgtag ttttctgaga
    18901 ttccagcacc tttacgtgcg ataacaacac cttcaaaaat ctggatacgt tcacggttac
    18961 cttcgacaac tttcgcgtgt acacgaacag tatcaccagg acggaatgat gggatatctg
    19021 tacgaagttg accttcagtc aagctttgga ttaatggatt cattttattc tcctatcttt
    19081 gtcaatcttg aggaatcttc ctcagcggat aaactgtatt tttgtgcgtc cattacacac
    19141 aagatatagt ttaccaaatt tctaaaaaaa agtaaagaaa tttatagcaa aattcctaaa
    19201 aaaatcgcaa ccaaaccacc taggtaggtc aaaatcaggt aagaataaaa taccttctta
    19261 tcgcttagca acctttgaag ttcgtcattc aaggtcgaaa aagttgttaa accgccacaa
    19321 aatcctgttg ctagaatagc atatacttcc ttagactcta catgattgta gaatactcca
    19381 attaaaaaac aacctaaaag attagctatg agcgttccga gtggcaattt agaagcttga
    19441 ttatagcgag aaaagaaata ccgtacgagt gctccgaaac cacaagcaat tgcaagatag
    19501 acgattacca tttcttcctc cctagaaaat aagctaagag taggcctcca ccgatgctca
    19561 aaagcaaata caggactaaa ctaaaataac gccctgtatc aagcagcttc acagtatcaa
    19621 gcattaggct ggaaaaagtt gttaaacctc cgcaaaaacc cgtccccagt gctaaaatca
    19681 agcccttact agtcccctta tagaccagat agcccttgac aagaaaaatc aagcagaaaa
    19741 ttcccagata gttgacaaag agagtgcccc aaggaaagtc tggactggct ggtaaccagg
    19801 tggaaactag atatcggaca agtccgccca acatagcagc tagaaaaatt cctagcggat
    19861 aaaattgttc ttttttcatt tgatattttg atcctgataa tcacgcgaac gtttgagtat
    19921 gtccgaaaaa gtcgctacaa tagtctcctg atagcgcttg tcctctacac gactcctaac
    19981 cttttcaaaa ataacttctt ctctcttagt atctaaaatc ggtttacctg aagctttctt
    20041 ataagcaacc accccctcaa ctaaatgcat tcgttcttct aacagtttga caatttggtc
    20101 gtcgatttga tcgatttctt gacgaataat atctaaatcc atacagtctc ctcctttatt
    20161 tgaattattg tatcaaaaag ccatcaatta ggctagtaaa atcccaactc tcgataagaa
    20221 aaatgcactg attgattaca tcagcgcact tttatgttta tcctacttta gcagccaatt
    20281 cttctgcgaa ttgttccaag cgttcaatat cttcttcctc ggcagaaaga tcaactttaa
    20341 cacactctga acctttttct gctcctgttg acacaaagac acggtcaaag tcatcaacag
    20401 ccttacagaa ttcatcgtag aaggtatctc ctgagccgac cactccgtag attttgccat
    20461 tcaagttgag atctgctagg tcttcgtaga agtccatcat ctcatctggc aattcaccat
    20521 caccataagt ataggtcgca acgatagcga tgtctgcttc caagaagtct gaagcgtcaa
    20581 cagttgtaca ttcatcaaca tcaacatcca agcccaagtc acgtaatttg tctgctacaa
    20641 tatctgcaat ttcttcggta ttaccggtca tactggcaaa tacaattttt gctaatgcca
    20701 tatcgtcctc ctcaatttat ctttctccat tatatcacat ctttttcatt ttaaaaataa
    20761 aaattcttgt gctacaatga aatgagaaag aattgaggtt atttatggag atttgccaac
    20821 aaattttaga aaaaattaaa gaatacgaca ccattatcat tcatcgtcat atgaaaccag
    20881 accctgatgc cttgggaagt caggtgggat tgaaagcctt gctggaacat catttcccag
    20941 aaaaaaccat caaagccgtc ggttttgatg aaccaactct tacttggatg gctgagatgg
    21001 atcttgttga agatagagcc taccaaggcg cacttgtcat cgtctgtgat acagctaata
    21061 ctgctcgtat cgatgataag cgctatagtc aaggtgattt tctcattaag attgaccacc
    21121 atccaaatga tgatgtatac ggtgacctgt cttgggtcga tactagttca agtagcgcta
    21181 gcgagatgat taccctattt gcccaaacaa cccaactagc cttggcagat cgcgatgctg
    21241 agttgctctt tgcaggaatt gtcggtgata caggtcgctt cctctaccct tctaccactg
    21301 cacggactct tcgcctggct gcttatttga gagaacataa ctttgacttt gcggctctca
    21361 ctcgcaaaat ggacactatg agctacaaaa ttgctaaact gcaaggctac atctacgacc
    21421 atctggaagt ggatgaaaat ggtgctgctc gcgttatcct gagtcaagaa gtcttgaaac
    21481 aatacaatgt aaccgatgct gaaactgcag ccattgtcgg tgcacctgga cgcattgaca
    21541 gagtgagtct ctggggaatt tttgtcgaac aggctgatgg ccactaccga gttcgcttac
    21601 gcagtaaaat ccatcctatc aatgaaatcg ccaaggagca tgatggtgga ggccaccctc
    21661 tagcaagtgg tgctaattcc tatagcctag aagaaaacga aatcatctac caaaagttaa
    21721 aaaacttgct taaaaactga taaaatactt gccaaacttt tcagaatctg atagactagt
    21781 atggtaacaa tctatggctc gcaaagagac catggcagaa aggaaatatt gcaaaatgaa
    21841 aaaagatatc catccagaat atcgcccagt tgtcttcatg gacacaacta ctggttacca
    21901 attccttagc ggttcaacaa aacgctctaa cgaaacagtt gagttcgaag gcgaaactta
    21961 cccattgatc cgtgtggaaa tttcatcaga ctcacaccca ttctacactg gacgtcaaaa
    22021 gttcactcaa gcagatggac gcgtggatcg tttcaacaaa aaatacggtc tcaaataatg
    22081 ataagagaac agtttcggct gttctttttt gtttcttgaa atcaactgct gttttcatgt
    22141 tccagactca tctgtaggtt cggtttccat gctactaggc aggaaggaaa tagctgtttc
    22201 aacacgtcca taatgagctg tactattgtc acgaaccaca ctttcattga tggtccaagt
    22261 ggaattcatt ttcttaaaag cttctcggac tttttccaaa tctttggagg caatggcctg
    22321 ttctaaggtt tcaaaacgag gacttagacg gtttaccaat ttttcctttt ccgcatctag
    22381 gtcaacagga ttttgttctt tttcaaaagc taatagagct gaggaaattt cggtgagttt
    22441 ggcttcagta atatctccag atagagctaa cttttcctta acaatcttac caacctcaga
    22501 atccttattt tctactcttt cgaagtctga tgccatcttc gtaacgagtt tctgggtctc
    22561 agtctgacca ccatttttaa ccgttttgga tgcatctgtg attttcacaa agaaaaaact
    22621 caagctttct tgggcacctg ctggggaaag aattaaaaat gacaaagcta aaactagtaa
    22681 ccagctttta gccttccaat aatttctgac caatgtagcc tcctttctcc acaccaccaa
    22741 agcaagtaaa aagtccacta cctatgtgag tgatgtattc attcatctta tcagtagcac
    22801 ctaggttagt ttgaacctta acaaagttat caggatcctt ctggaaagaa atgaagagca
    22861 atcccgtatc aaactgacca gtcttttcat caatgccatc tgagtaagaa taagaacgac
    22921 gtaaaagtgg cttatccact tctttggcca aacaaacatg cgaatcatca ggtaagagac
    22981 tcaaatccac ttcatcaaac tcatttttct taccaaaggg ggcaccgctt tccttgtaac
    23041 gaccaaaggt attttcttgt tcttcgagac tagtgcggtc ccaggtctct aaaaacatct
    23101 gaatccgacg aactgccata taagaaccat tttccatcca gtccttacta tcagcccaga
    23161 taacgcggtc aaagtcttgc tccttggttg gatttgctgt tccatcctta aaaccaaaga
    23221 ggttccacgg agtctccatt cgatccccga tagctgcaaa tccagactga ctccaacgaa
    23281 ggggcaccgc atttctcccc ttacggatga gattgcgaat agcgtgaaag gcaatttgct
    23341 catcatctgc acaagcatga atcacaatat ctccaccagt atatttttca cgtaattgct
    23401 ccttaggaaa tagaggtaaa tccctgaaca gtcgagggcg cttgttttcc aagttcatcc
    23461 ttttcaagaa acttgcagat acaccaaaag tcagcgtcaa acgatgagga ttgagcccaa
    23521 ctgtctcacc agtatcgctc ggaggaaaga gagcattctg tccatctttt ttaaccaatt
    23581 ccccctcgac caacttggca ctataatccg tccaatcctt gaatagctgg ataattttat
    23641 ctctatccgt cgtatgcagg tccaagacaa caaaatagat attcttttgc atgggcgtac
    23701 tatttggtac atcaagcgaa ccttacgaaa acgtctacta tatttaaacc gctttcttgt
    23761 cttcttgaat tgagatttta tttttagacg cgacaatggt ttgagcgtct gctttcttag
    23821 gatgttctgg acgtggcata atatttcgcc aaccatggcg cttcaacagt tgatagaagg
    23881 cgtcacgtgt gtaggaacga cctaactcct ttttataagc ctgaaataag gcatcaattg
    23941 taacaaattc tcctgactct gcagccttca aatgacgggc aagaaaggct ttctcttcct
    24001 caactgtcat atatgcatgg ttacgaccac tacgtgtttc ttgaaggaga gagtcgagtc
    24061 cgaactcctc atattttttt acatttcgct aaatcgttgt ttgattacag tctaaaagtt
    24121 ctataatctc tttataagat ttgcccatca gacgaaatat aataaattga aactagaata
    24181 gtacacctct acttctaaaa tattattaga aatc
//
LOCUS       DAVLTT010000026        23202 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLTT010000026 DAVLTT010000000
VERSION     DAVLTT010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23202
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.026"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            3464..4800
                     /locus_tag="VYN15_001165"
                     /pseudo
     CDS             3464..4800
                     /locus_tag="VYN15_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
     gene            4781..4984
                     /locus_tag="VYN15_001166"
     CDS             4781..4984
                     /locus_tag="VYN15_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452489.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            4987..5337
                     /locus_tag="VYN15_001167"
     CDS             4987..5337
                     /locus_tag="VYN15_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452490.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPTVEPKE"
     gene            5346..5762
                     /locus_tag="VYN15_001168"
     CDS             5346..5762
                     /locus_tag="VYN15_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEV1452491.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLFRKISGVLLLMILIPASVLLPEKTGFAFLYSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            5766..6098
                     /locus_tag="VYN15_001169"
     CDS             5766..6098
                     /locus_tag="VYN15_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV1452492.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKDYLVQKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKNLDTFVESAVKQ
                     MNDVWKGR"
     gene            6102..7058
                     /locus_tag="VYN15_001170"
     CDS             6102..7058
                     /locus_tag="VYN15_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1452493.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLTKWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(7329..7508)
                     /locus_tag="VYN15_001171"
     CDS             complement(7329..7508)
                     /locus_tag="VYN15_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452494.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(7650..7799)
                     /locus_tag="VYN15_001172"
     CDS             complement(7650..7799)
                     /locus_tag="VYN15_001172"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452495.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            8081..8548
                     /locus_tag="VYN15_001173"
     CDS             8081..8548
                     /locus_tag="VYN15_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV1452496.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVETGILEDECAAIMQDFFRNRRKK"
     gene            8581..8678
                     /gene="ffs"
                     /locus_tag="VYN15_001174"
     ncRNA           8581..8678
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VYN15_001174"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            8735..9178
                     /locus_tag="VYN15_001175"
     CDS             8735..9178
                     /locus_tag="VYN15_001175"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV1452497.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAAGGVRTGGFGSTGH"
     gene            9180..9695
                     /locus_tag="VYN15_001176"
     CDS             9180..9695
                     /locus_tag="VYN15_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1452498.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGEMLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            9709..11070
                     /gene="radA"
                     /locus_tag="VYN15_001177"
     CDS             9709..11070
                     /gene="radA"
                     /locus_tag="VYN15_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV1452499.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            11143..11640
                     /locus_tag="VYN15_001178"
     CDS             11143..11640
                     /locus_tag="VYN15_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV1452500.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     AVVEL"
     gene            11665..12480
                     /locus_tag="VYN15_001179"
     CDS             11665..12480
                     /locus_tag="VYN15_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV1452501.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLLGWLSSFANTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKFLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            12625..13593
                     /locus_tag="VYN15_001180"
     CDS             12625..13593
                     /locus_tag="VYN15_001180"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1452502.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(13727..14008)
                     /locus_tag="VYN15_001181"
                     /pseudo
     CDS             complement(13727..14008)
                     /locus_tag="VYN15_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(14137..14370)
                     /locus_tag="VYN15_001182"
     CDS             complement(14137..14370)
                     /locus_tag="VYN15_001182"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452503.1"
                     /translation="MFSQLHMREEQVLLAQDYPLETARAEGLEQGLERGKVEGREERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            complement(14363..14479)
                     /locus_tag="VYN15_001183"
                     /pseudo
     CDS             complement(14363..14479)
                     /locus_tag="VYN15_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
     gene            complement(14694..15044)
                     /locus_tag="VYN15_001184"
     CDS             complement(14694..15044)
                     /locus_tag="VYN15_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1452504.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            15300..17933
                     /gene="polA"
                     /locus_tag="VYN15_001185"
     CDS             15300..17933
                     /gene="polA"
                     /locus_tag="VYN15_001185"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV1452505.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            18018..18455
                     /locus_tag="VYN15_001186"
     CDS             18018..18455
                     /locus_tag="VYN15_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV1452506.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLLDVARDFLKADA
                     KIFWAQLGLESLKAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(18638..19648)
                     /locus_tag="VYN15_001187"
     CDS             complement(18638..19648)
                     /locus_tag="VYN15_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV1452507.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            19797..20966
                     /locus_tag="VYN15_001188"
     CDS             19797..20966
                     /locus_tag="VYN15_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1452508.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTSQLIKSHQYLVTAANTMAQH
                     AAVEALTSGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            20963..21733
                     /gene="recO"
                     /locus_tag="VYN15_001189"
     CDS             20963..21733
                     /gene="recO"
                     /locus_tag="VYN15_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV1452509.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKCMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMETGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            21730..22722
                     /gene="plsX"
                     /locus_tag="VYN15_001190"
     CDS             21730..22722
                     /gene="plsX"
                     /locus_tag="VYN15_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV1452510.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            22728..22961
                     /locus_tag="VYN15_001191"
     CDS             22728..22961
                     /locus_tag="VYN15_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1452511.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            23007..23202
                     /locus_tag="VYN15_001192"
                     /pseudo
     CDS             23007..23202
                     /locus_tag="VYN15_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6784 a         4241 c         5588 g         6589 t
ORIGIN      
        1 acttagtcgg actaagaatg aactgtctgg cgtgaagtca gcgcaagcga cgtatgagga
       61 gacgacgact cgtagactgt cagaactgac caacttggcc aatggtaaag ccagcaagtc
      121 agaactcacg caaacagctg aggagctggc tagtcggatt gcgagtgtgc aggcaggtag
      181 ttcacggaat tacttcagga attcacgttc aagaacgttc acaacaggag gtcaagcggt
      241 atacgactat cgaacattca tagttcctga tttctggaag aacagtgaca ggttcaagcg
      301 tgattatgtt cgcatatctt ttgatgtgac tttccctgtc gccctagtaa atgacatgcc
      361 tgctatggtg cattttagtg ctcatccatg gtatgcctac agaaacttaa tttttaaagg
      421 tggaactgtc gaacgccaac attttgagtt tacgattgac ttgtctagtt cttctgagga
      481 ctatcagact aataatgtgt tcattcgttt tggtactaat tatggatttc ctgctggtct
      541 gcaggtcgtc attgagaacg ctatgttatc ggttggtaat tattttccag cctatcaacc
      601 agcgtatgaa gaccaagaag accgtgtctc agtagtcgaa tccaacttta agcagcgtgc
      661 tgattcactc gacgctggtg taagccgtct gactgaaggc cttagaacta aagccgatat
      721 cagctcactc aatgtgactg ctgaaaatat ccggcaatct gtgaagaggc ttgagacaga
      781 cacgcagaac aagctaaatc agaagttgag tcaggctgaa tttgaggtgc gagctggctc
      841 tatccgtcag gaaatcctga atgcaaccaa ggataaagcc agcaagtcag aactcacgca
      901 gacagctgag gagctagcta gtcggattgc gagtgtgcag gcatccggtc gaaatctatt
      961 cttgaactca ctattcaagc aggatatttc aaaaacagga atttggacaa cgagtacata
     1021 tacggctgct atcgatagcg aaagtaagta tcttggatat aacgctctta aaattatagg
     1081 tctgaatcca tctggccgtg atggagggaa tcccaaggtt acttatccag ctctgggtca
     1141 attcgggaaa gtaattcccg gaagtacgac taatcaagat gtaaccatta gtttttatgc
     1201 taaggcaaat aaaaatggaa taatgctaag atctcgatta gggaatatcg gatataaaac
     1261 tggaaatgtg acattgtcga cagaaattaa gcgatatgtt gtccatattc caaaaggttg
     1321 gacaaacgaa tccaagcaga ccacaaatga atggttgttc aatttcaacc aggaaggaac
     1381 catttggatt tggatgccga agtttgaaat aagcgatgta gatacttctt attcagaagc
     1441 tcctgaagat atagaaggtc agatttcaac agtagaatcg acctttaaac aacgagccaa
     1501 ctcgctcgac gctggtgtga gaagcttgac tgaagggctt agaaccaaag tggatatcag
     1561 ctcactcaac gtgactgctg aaaatatccg gcaatctgtg aagagtcttg agacagacac
     1621 gcagaacaag ctaaatcaga agttgagtca ggctgaattt gaggtgcgag ctggctctat
     1681 ccgtcaggaa atcctgaacg caaccaagga taaagcagat aagactttag ttgtatctga
     1741 agctgggaaa ttgcgtgaag aattttcaaa aatgaaggtg ggaggacgga atctatggat
     1801 aaaatccaag acggttggag ctgtaattga aaaattacct gaaaaccacg tcacaggtca
     1861 aaaagaatgc tataggctag agaacaactc tactttaacg ttcaacattg aaccagattt
     1921 cagctcaagg ttgtatcaaa aagttacttt tagcgcttgg gtcaagtacg aaaatgtagt
     1981 ccaaggtcga aatttttgga atgtatttaa ttgcttcaaa cattatcttt ttagaaaaaa
     2041 tagtgagacc ggagtacaga gtggtccaga ttatgctacg cttggtatgt ataaaggttc
     2101 ggcagattgg aaatatatta cattcactta tgactactct gaaaaaacaa attttgatca
     2161 attgaagaca tcattgcgat tcaatcttga aggtgctaca agcggtacag cttgggtaac
     2221 aggaatcaag gttgaaatcg gtagtgtggc gacggactgg agtcctgcgc ctgaggacgc
     2281 tgatggtctc atcactgaag ctaaggctac ctttgagcgg acagctcagg gcttgcgaac
     2341 cgatttatca gctattcagg aatatgtaaa taaagacggt cagcgacagg aagccctaca
     2401 gcgctatact cgtgaggaga gcacgagaca agcgatagca gtccgtgagc tggtcaatcg
     2461 tgatttcgtt ggtaaggcta cttatcaaga agatgttaag ggtatcaatc aaaggattga
     2521 agctgttaaa actagtgcga ataaagacat cgctagtcaa atcgctagct atcgtcaatc
     2581 tgtagatggt aagttcacgg atatttcaag tcagataact acttataagc aagatgtggg
     2641 cggtcaaatc agtggccttt caaatagact tacaagcagt gagcaaggaa ccactactca
     2701 gatttcaaat ctttcaaatc ggataaacag taataaacaa ggcgcagata atcagatttc
     2761 aaatttaaag actcaggtcg ctacaaacaa ggataatgct gaacgacaaa tgggtagaat
     2821 atctgatcag gtttctgcaa acaaagcgaa tgctgatagt caatttgcga atgtgaccaa
     2881 tcaactagtg cgaaaagtag agactactga cttccagcgt gttaaggaaa ccagtaaact
     2941 ttacgagcgg attttgggca atactgaaaa tggaattgcg gataaggttg ctcgcatggc
     3001 tctgaccaat caactgtttc aggttgaggt tgggaaggtt gccaaaggtg gtcgaaatta
     3061 tatcagaaat ggtcaattta agaacggttc gaaaaactgg cttgaatatc aatctgttaa
     3121 ttttggtttg aatttcaact atcaacactc tcaaaatcct aataatcgaa atcgtccagg
     3181 actacacttc tatcacgatt ctcaagatgt tgctaatttt tttggaattc agcaatcttt
     3241 tgcatttgat ggtgttcgag gtgagaaagt gagtgtatct cttcttgttt cgaaagatgg
     3301 tggcgatagc aacagtggct tgaaagtcgc tttgcactac atcaaaaaca aaaacattat
     3361 tgggcaagag tggcaaaata tcccaagtcc acaaataaca tcgaagtata agcgtttcac
     3421 atttacgttt actttatcag acgatgtaga gaatctgaat ttgatgttgt ttggtgaaaa
     3481 agggaagacc atcaacctct atgttacaga tgttcaactc gaaagaggtt ctgtcgcgac
     3541 ggattacaaa gaagctcctg aagacacgga cgaagcgatt cgctctgttc aaagccaact
     3601 aactggctca tgggcagttc aaaacatcaa ctcggctgga gatatcatct ctggaatcaa
     3661 tcttggcgcc aatggacata accgctttgt tgggaaattg acccacatca ctggagagac
     3721 cctgattgac agagcagtca tcaagtctgc catggttgat aagctcaaaa cggccaattt
     3781 tgaagctggt tcggtcacga ctacgatatt agacgctgaa gcggtaactg ctgagaagtt
     3841 gaaagttgac aatgcgctta ttagaaaatt aactgcaaat gatgctttta ttgaccaact
     3901 gatatctaaa cgtatcttct ctactaaggt tgagtccgtc atttctagct caaccttcct
     3961 agaagcctat caaggccgaa tcggtggatt cacacttggt caatttgacc agggtggcgg
     4021 tcgctggatt tcaggtgtca atcagttctc tgttggtatg gggaatggtg ccgggtatgg
     4081 agtccggaca gccttctggg cgaactgggg aaataattgg aactatgccg gacctaaagc
     4141 atggaacgtc aatactgatg ggaaaatgta ctgtaggaat gaagtcggtt tttatgatca
     4201 agtggatttt tcgaattcat cgagagcaaa cttctatggg aatactactt tttctcgttc
     4261 tcctgtgttt tcaaatggta tcgaacttgg aagtaaagat gtgcttggtg atggttggaa
     4321 tcccaaaggc ggaaggaatg cggttgtttg gtggaatcag gtcggtagcg gtagcgtgaa
     4381 gtattggatg gaacaaaaat cagacagacg cttaaaagag aacatcacag atacagctgt
     4441 gaaagccttg gacaaaatca acagattaag aatggttgca tttgatttca tcgaaaataa
     4501 aaaacatgag gagattggtc taatagctca agaggctgaa accatcgttc caaaaattgt
     4561 ctcacgagat cctgagaatc cagatggcta tctgcatatc gactataccg ctttagttcc
     4621 ttacttaatc aaggctattc aagaattaaa tcaaaaaata gaaaaaatgg agaaaacaat
     4681 agcatgaata acaacatgtt gaccaatatc gcacttaaag caatttagga gcttgctctt
     4741 gaaaatagaa aacgaacaca cagattggag aacttagaaa atgaacacag aacagcttaa
     4801 ccaagcctta caaatgacaa ttagtgaaat gtcaacaact tcaacaaatt cgatgattac
     4861 aagtaatatc ttgagtattc agttgaatga gcaaagggaa gagaatcaaa gacttcaagc
     4921 acgagtggat gagctggaag ctctgcttga tgaacaaact aaaccagcag acaaaggaga
     4981 atagacatgg cagaaacaat tcaaaacaca gataacttac tagaccttac aaaaatcaca
     5041 gaaccatttg atcttgcgag cgctttgcgc tacatgaaag aaaatggaga gttcattcgt
     5101 tgcaagaatg taagcgatga cttctatatg tatcgtgacg ttcaaaaacg tcctgtgatc
     5161 gtaaatggcc gtcgccaatt caaggatgtt gaaaccgttt gggcgttcaa tcagtggggt
     5221 ggtacaatcg caacaatcaa cgtagccgtt ctgttgaatc atgaattcta tatcatgaaa
     5281 tttgatgcag agggcaatcc tgactggacg gttccaacgg tagaacctaa agaataggag
     5341 gttgtatgca aattgaattt ttcaattttc taagaagtgt cgtacagact gaagatggtt
     5401 tggtattgta cgctctagca ctgattgtct caatggaaat cattgatttt gtgacaggga
     5461 cgattgcggc aattatcaat cctgacatcg agtacaagag caaaatcggc atcaatgggc
     5521 tatttcgtaa gatttcaggg gttctcttac tgatgatcct cattccggcg tccgttttgt
     5581 tgcctgaaaa gacaggtttt gcattcttgt actcaatcta tctcgggtac atcgcattta
     5641 cttttcaatc tctcattgaa aattaccgca aattaaaagg aaatgttact ctttttcagc
     5701 cgattgtaaa agtatttcag cgattacttg aaaaagatga tgatacgaaa aaaggagaat
     5761 aacaaatgca acaaattact gaaatcatta ctaatggagc aatcagcatc cttgttattt
     5821 tggctggtat cgcagtcaag gcagtcaagg actacctggt tcaaaaaggt ggagaaaaga
     5881 ccatcaaaat cgttgaaatc ttggccaaaa atgcagtaaa tgccgtggag caggtagctg
     5941 ctgaaactgg ctacaaggga gatgaaaaac tggcacaggc tcgtgctaaa gtccgtgctg
     6001 agcttacaaa atacaatatt agcatgactg acaaaaactt agacaccttc gtagagtcag
     6061 cagtgaagca gatgaatgac gtatggaaag gacgataggg aatggatatc gatagaaaca
     6121 gactacgtac aggcttgcca caggttgggg tgcagcctta tcgacaagta catgctcact
     6181 caacaggtaa ccgcaactca accgtacaga atgaagcgga ttatcactgg cggaaagacc
     6241 cagaattagg ttttttctcg cacgttgttg ggaacggccg tgtcatgcaa gtaggtcctg
     6301 tgaacaacgg aagttgggat gttgggggcg gttggaatgc tgagagttac gcagcggttg
     6361 aactgattga aagccattca actaaggaag agtttatggc tgactaccgc ctctatatcg
     6421 aattgctacg caatctagcg gacgaagcag gcttgccgaa gactcttgat acagacgact
     6481 tggcaggtat caagacgcat gaatactgta ccaataacca accaaacaac cactcagatc
     6541 atgtggatcc atacccttac ttgacaaaat ggggcattag ccgtgaacag tttaagcaag
     6601 acatcgaaaa cggcttgagc gctgcaacag gctggcagaa aaatggcact ggctactggt
     6661 acgtacactc agacggctct tatccaaaag ataagtttga gaaaatcaac ggtacctggt
     6721 attatttcga tggctcaggc tatatgcttt cagaccgctg gaagaagcac acagacggta
     6781 attggtacta ctttgaccaa tcaggcgaaa tggctacagg ctggaagaaa atcgctgaga
     6841 agtggtacta ttttgatgta gaaggtgcca tgaagacagg ctgggtcaag tacaaggaca
     6901 cttggtacta cttagacgct aaagaaggcg ccatggtatc aaatgccttt atccagtcag
     6961 cggacggaac aggctggtac tacctcaaac cagacggaac actggcagac aagccagagt
     7021 tcacagtaga gccagatggc ttgattacag ttaaataaaa tagaaaggaa actttctaaa
     7081 ttgttctttc accgcaggct caggcttgcg gtttttttgt ttgtctgaat caagaaaacg
     7141 tctaaccaac cgacaccaat gtcggtagca aaataaatgg tttgcctaaa aaattagagt
     7201 taagttctat ttttcaaaaa cacgcatttt gaacgattag aaacagaaat ctaaatccta
     7261 ttgttcaaaa aaacgtttac atgaaaaata gggaggtgtt ttgttaaaaa taaaaacagt
     7321 gatcgaaatc actgcttatc agttgtagca aattcataaa gtttttctgc tgtgagaagt
     7381 gccattttgt ccatgcttgt ttttcctttt ctgaggtcag aaacagtagt ccatggaact
     7441 ccagcacctt gggaaatagc agatgtagac atcgaactgt ctaacaattc ttgaataact
     7501 tctctcatct tatttgtcct ttttattttt tagataaata tatacattga ttgcaattat
     7561 aaaaatagct attgcactaa ccattgcatt tcctctttcc atttgataaa atagaggtgt
     7621 aaggggcttt cgccccaacc tcttagcgtt tacctttttc tttgacggga tttcggttta
     7681 cgctttttgt tttgccttgc gaccgttatt gcggtcacta gacttgcgat agcagttacc
     7741 gtttcaggaa tattgtctat tgccttttca agtaacctga gccaatcttc tttgttcaac
     7801 ttcatcaccc cctttcctta tcttgattat attatatcac ggtacaccga gaaagtcaag
     7861 cgttttgatg aagttttttt aattttttca aaaaaaaaat agaccttgtc cagaggtcgg
     7921 ggagttggag gggacaccct ccaagagtgt tgatttaata agattttatt ttaccttttt
     7981 cataataatc tccctataga gtcaccgcat tcggtggctt tttttgtgtt gggattcatg
     8041 atataataat aaaatcgata agtaggaaaa gagaaaagag atgtattata cgcttgaaga
     8101 aaaagaagtc tttatgaggg aggctttgag agaggctgag attgctcttg aacacgatga
     8161 aattccaatt ggttgtgtga ttgtcaaaga tggggaaatc attggtcgtg ggcataatgc
     8221 gcgtgaggaa ttacagcgag cggttatgca tgcggaaatt atggctatag aggatgcgaa
     8281 cttgagtgag gagagctggc gcttgctgga ttgcacactt tttgtgacca ttgaaccttg
     8341 tgtcatgtgt agtggggcga ttgggcttgc ccgcattcca aatgtggtct atggggctaa
     8401 aaaccagaaa tttggcgctg ctggaagttt gtacgatatc ttgacagatg agcgtcttaa
     8461 ccatcgtgta gaggttgaaa cgggaatttt ggaagatgaa tgtgcagcta tcatgcagga
     8521 cttttttaga aatagacgga aaaaataatt ttgcttttaa aatgaatagg aatgtgatat
     8581 aataaatagt ggagcaacag ttctgcgtga agcgggtcag gggaggaatc cagcagccct
     8641 aagcgatttg aattgtgtgc tctttttttc gtgctttttc cgaataaata agatagaata
     8701 atctagaata aatgataata gaaaagagaa aattatgaaa attcgtggtt ttgaattggt
     8761 ttcgagtttt acagatgaaa atttattgcc caagcgtgag acagcgcatg cggctggtta
     8821 cgacttaaag gttgctgtgc gtacagttgt tgcgccagga gagattgtct tggttccgac
     8881 aggggttaag gcttatatgc agccgactga ggttctctac ctctatgatc gttcttcaaa
     8941 tcctcgtaag aagggcttgg ttttaattaa ctcagttggg gtcattgatg gggattatta
     9001 tggaaatcct ggaaatgaag ggcatatttt tgcgcagatg aagaatatca cagaccaaga
     9061 ggttgttctt gaagttgggg aacgtattgt ccaggctgtt tttgctactt tcttaattgc
     9121 agatggagat gcagctggtg gcgttcgaac tggtggattt ggatcgacag ggcactagaa
     9181 tgaagattat ctttgtacgt catggggagc cagattaccg tgagttagag gagcgttctt
     9241 atataggatt tgggatagat ttggcaccct tgtctgagat gggacggcag caagtccaga
     9301 aattgagcaa aaatccttta ctctcgtcag ctgaaataat cgtatcttct gcagtcacaa
     9361 gagctttaga aacggcttcg tatgtggtct gtgctacggg tcttccttta agagtagagc
     9421 ctttattaca tgaatggcag gtctataaaa caggaataga aaactttgaa acagctagaa
     9481 gactgttttt agaaaacaag ggggagatgc ttcctaatag tcctattcaa tatgagacag
     9541 ctacggaaat gaagtctcgg tttctagaat gtatgtctaa gtatcgagaa catcagactg
     9601 tggtagttgt tgctcatcga atgctcatgc gccagtttgt gccaaatgag aagattgatt
     9661 tttgccaagt gattgagtgt gagttagaga tatagaaaga ggtttgtcat cgcaaagaaa
     9721 aaagcgacat ttgtatgtca aaattgtggg tataattccc ctaaatatct gggacgttgc
     9781 cccaactgtg ggtcttggtc ttcttttgtg gaagaggttg aggttgccga ggtcaagaat
     9841 gcgcgtgtgt ccttgacagg tgagaaaacc aagcccatga aactagctga ggtgacttcc
     9901 atcaatgtca atcgaactaa gacggagatg gaggaattca accgtgtgct tggaggcgga
     9961 gtggtaccag gaagtctcgt cctcatcggt ggggatcctg ggattgggaa atcaactctt
    10021 ctcctacaag tctcaaccca gttgtcccaa gtggggacag ttctctatgt cagtggggag
    10081 gagtctgccc agcagattaa actacgtgca gagcgcttag gtgatattga tagtgagttt
    10141 tatctctatg cagagaccaa tatgcagagt gttcgtgcag aagtggagcg tatccagcca
    10201 gactttctca ttattgattc catccagacc atcatgtctc ctgagatttc aggggtgcag
    10261 gggtctgttt ctcaggtacg tgaagtgacc gctgaactca tgcagttggc caagaccaat
    10321 aacattgcca tctttatcgt aggtcatgtg accaaagaag gaaccttggc tgggcctcgt
    10381 atgttggagc atatggtgga tacggtgctt tactttgaag gggagcgtca ccacaccttt
    10441 cgtattttga gagcggtcaa aaatcgtttt ggttccacta atgagattgg gatttttgag
    10501 atgcagtcgg gcggcttggt tgaggtactc aatccgagtc aagttttcct agaagagcgt
    10561 ttggatgggg cgactggttc ctccatcgtt gtaaccatgg aagggacgcg tccgattttg
    10621 gcggaggttc aggctttggt aacaccgacc atgtttggaa atgccaagcg tactacgaca
    10681 ggacttgatt ttaaccgtgc tagcttgatt atggctgttt tggaaaaacg ggcagggctt
    10741 ctcttgcaaa atcaggatgc ctatctcaaa tctgctggtg gtgttaaatt ggatgaacct
    10801 gccattgact tggctgttgc agttgctatt gcttcgagct acaaagacaa gccaactaat
    10861 cctcaggaat gttttgtcgg agaactgggc ttgacaggag agattcggcg cgtgaatcgt
    10921 attgagcaac gcatcaacga agctgctaaa ctgggcttta ctaagattta tgtacctcag
    10981 aattccttga caggaatcac tctgcctaag gaaattcagg tcattggcgt gacaacgatt
    11041 caggaagtct tgaaaaaggt ctttgcataa tccgtgacaa attctcttaa aaatgataag
    11101 ataggagaaa tatttgacta tcaaattttc aaggagggaa tcgtgtcgta ttttgaacag
    11161 tttatgcaag ccaatcaggc ttatgttgcc ctacatgggc agttaaatct gccacttaaa
    11221 cctaaaacca gagtagccat tgtgacctgt atggactcac gtttgcacgt tgcgcaagct
    11281 ctaggtttgg cacttgggga tgctcatatt ttgcggaatg caggtggtcg agtgactgaa
    11341 gacatgattc gttcgctagt tatttcccag caacaaatgg ggacaagaga gattgtggta
    11401 ttgcaccata cagactgtgg tgctcagacc tttgaaaatg aaccttttca ggagtattta
    11461 aaagaggaat taggtgtaga tgtgtcagac caggatttct tgcccttcca agatatagaa
    11521 gagagtgtac gcgaggatat gcaactgctt atcgagtctc ccctaatacc agacgatgtc
    11581 attatctctg gtgccattta caatgttgat acaggaagta tggcagtcgt agaattataa
    11641 atacttcatt tagaaagaaa gtgtatgaag aaaagcagta ttttatttat ttttatttta
    11701 ttgctatgta ttggtttaca gtatgaaacc atctactata cggacggttc gaggtcaggt
    11761 gcggaatatg gactaatggg agtttctatc tttctagctc tcttttacat gattccggct
    11821 ctttattttc tcttccgtat tgggaaaaaa tgggaattgc caaagaaggt tttgattctg
    11881 tctttattgg gagggatgtt ccttttaggc tggttgtcta gttttgctaa tacttatatc
    11941 catgatttac tgggggttct tttcccagat agtccatttt taaatgcctt tgaaagtgct
    12001 attgtggctc ctttggtaga agaacccttg aaattattgc cacttgtttt tgttttggct
    12061 ttgattcctg tgcgaaaatt aaaatttttg tttttacttg gaattgcttc cggtttggga
    12121 ttccaaatga ttgaggatat tggttatatt cgtacggatt tgccagaggg ctttgacttt
    12181 actatttcgc gaattttaga gcgtatcatc tcaggaattg cctctcactg gactttttca
    12241 ggtctagctg tagtaggtgt ttacttgctt tacagagcct ataaaggaca gaaggttggc
    12301 aagaaacagg gccttatttt tctaggttta gccttgggaa ctcacttctt gtttaactct
    12361 ccttttgtgg agttggaaac agagttgcct ttagcgattc cagtggttac ggctattgct
    12421 ctctatggtt tttatcatgc ttattgcttt gttgagaaac acaatgagtt gatgacctag
    12481 aatatttttc aaaagaatga tgcaagggta caaatatggt gcccttcttt tatttttgat
    12541 tgaaaaatag tgcaaaaagc gctacaatgg tagatggaaa atcttgtgaa aagcacaagt
    12601 tatacatata taccggagga aatcatgtct ttttctgatt taaagctgtt tgccctttct
    12661 tctaataaag aattggcaga acgtgtggcg caggagattg ggatagagtt ggggaaatca
    12721 agtgttcgcc aattttcaga tggagagatt caggtcaaca ttgaagaatc aatccgtggg
    12781 aaacacgtct ttatcctaca atcaactagt tcgcctgtaa atgacaatct gcttgaaatt
    12841 ttgattatgg tagatgcttt gaagcgtgcg agtgcagaat ctgtcaatgt tgtcatgcct
    12901 tactatgggt atgcacgtca ggatagaaag gcgagagcgc gtgagccaat cacttcaaaa
    12961 cttgtcgcaa atatgcttga agtagctgga gtggatcgtt tattgaccat cgacttgcat
    13021 gctgcgcaaa ttcaaggatt ctttgatatt cctgtggatc atttgatggg tgctcctctg
    13081 attgcagatt attttgagcg tcgtggtatg gttggttctg actatgtggt tgtcagcccg
    13141 gaccatggag gggtgactcg tgctcgtaag ttggcagaat ttttgaaaac atctatcgct
    13201 attattgata aacgtcgtag cgttgataag atgaatacta gtgaagttat gaacatcatc
    13261 ggtaaggttg aaggcaagac ttgtatcttg attgatgata tgattgatac cgctggaacg
    13321 atttgtcatg cggcagatgc tcttgcggaa gctggtgctg ttgaagtcta tgcaagctgt
    13381 acgcacccag ttctttctgg tcctgctacg gacaatatcc aaaaatcagc tattaagaaa
    13441 ttggttgttt tggataccat ctatcttcca gaagagcgtt tgattgataa gattgagcag
    13501 atttcaatcg ctcatctcct aggggatgct atcgtacgta ttcatgaaaa acgaccactt
    13561 tctccacttt tcgatattga gaaaaaaatt taatgaccaa gcctgagatg attctcaggt
    13621 tttttcgtct tttttccgaa taaatagata gtagcggtga atctagtaaa gctagattta
    13681 aaactgtgat ataataaaaa gagaagaaat atgactgtac gtcatcagaa gtttcagcga
    13741 ccatcatttt tgaacagtga tagcacttga atcgacgctt tctaaggaga attctagtag
    13801 gcataccagt cgtttcaaga taaggaattt tagaaggttt ttgaaagtca tatttcttca
    13861 attgacttcc gcactcaggg caagatgggg cgtcgtagtc cagtttggcg atgatttcct
    13921 tgtgtgtatc cttattgatg atgtctaaaa tctggatatt agggtcttta atgtctagta
    13981 attttgtgat aaaatgtaat tgttccatat gattcttttt aatgagttgt tttgtcgctt
    14041 ttcattatag gtcatatggg actttttttc tacacaaaaa taggctccat aatatccata
    14101 ggggatttac ccactatgga tattatggag cctattttac aacagtgcct caaattcaga
    14161 tactgacata cctaattgct ggctggcaac ctcagaagtc agaagacctt ggcgtactat
    14221 gtctaggaag gcaaaaagtt tcctttcttc ccttccttca actttcccac gctctagtcc
    14281 ttgttcaagg ccttcagccc tagcagtttc caagggatag tcctgtgcta acaagacttg
    14341 ttcttctcgc atatgtagtt gactaaacat tttcctgtcc tcctcggacc agctcttgta
    14401 gtccagcagt tggtctgctt ggctgatggc tcgctcaggt tgctgggtaa agggcttgtt
    14461 gccgaaaaac tccaaccatg gcttgcgaac cttgtctttg ctggtttctc tgtatttttt
    14521 aattccaaga atgccatctt aaccagatgg ttttcctgtc cattgttggt aatcgccaat
    14581 acctcacctg ttgtgtcttc gcgcatacta aagctatgaa aagccaggtc atctgagaaa
    14641 taattactat ccacgatagc aatggcgtaa acaggagcga tgtgtttgta gctctagtga
    14701 gtatcacctt ctcgctgacg aattttttca agattttgat taacctgact gcacaggtaa
    14761 gcccacaagt gattgatgaa aaaattctga tgatggactt gaatctcaat aattacttga
    14821 gtaccgttat ccaactccgc caagacgtct atactggtat aaaaatcctg caccgagtaa
    14881 ggcatggaga gtaatacgtg aatatcgctt ccctccaaaa tggtcacatt ttttgctggc
    14941 aagtccagca tatcgcgaat aaattgacaa gtgatttctg gattgctgaa tattttctta
    15001 gcaatcaaat cattagttgg gctgatgccc ggatgtctga gaatcctcct attcctcctt
    15061 ctatagtgag ttgaaataag atgtgaataa ctctatcagg aaagtcaaat taatttatag
    15121 aaatatttta gcagtcaagg tgtactatta tagattcaat atactatgtt atagcacatt
    15181 tttaaatcta ggtttactaa attctctggc tctatctatt tattcggaaa aagtttgaaa
    15241 aatacttgct ctagctcttc ccaatggtat tttttgattc tttcctttat aatgggtgta
    15301 tggataagaa aaaattatta ttgattgatg ggtcttctgt agcttttcgg gcgttttttg
    15361 cgctgtatca gcagttggac cgttttaaga atgcggctgg tttgcatacc aatgcgattt
    15421 atggtttcca gttgatgttg agtcatttgt tggagcgggt tgagccgagt catattttgg
    15481 tggcttttga tgcgggaaag acgaccttcc ggacagagat gtatgcggac tataagggtg
    15541 gtcgggccaa gactcctgat gagtttcgtg agcaatttcc tttcattcgt gagttgctgg
    15601 atcatatggg gattcgtcac tatgagctgg ctcagtatga ggcggatgac atcattggga
    15661 cgctggataa gctagcagag caggatggtt ttgatattac cattgtcagt ggggacaagg
    15721 atttgattca gctgacggat gagcatacgg tggttgaaat ttccaagaaa ggtgtggctg
    15781 agtttgaggc ctttacgcca gattacctca tggaagaaat gggcctcaca ccagctcagt
    15841 ttatcgatct caaggcgctc atgggtgata agtcggataa tatccctggg gtgaccaaag
    15901 tcggtgaaaa gacgggtatt aagctcttgc tggagcatgg ttcgcttgag gggatttatg
    15961 aaaatattga tggaatgaag acttctaaga tgaaggaaaa tctcatcaat gacaaggaac
    16021 aggccttttt gtctaaaaca ctagcgacca ttgataccaa ggcaccgatt gcgattggtt
    16081 tagaggactt ggtctatagt ggtccagatg ttgaaaatct tgggaaattt tacgatgaga
    16141 tgggcttcaa acagctcaag caggctttaa atgtgtcgtc agctgatgtg gctgagggtt
    16201 tggattttac tattgttgac caaatcagtc aagatatgct gagtgaagag tctatcttcc
    16261 actttgagct ttttggtgag aattaccata cggataattt ggttggattt gcctggtctt
    16321 gtggggataa gctctatgcc acagacaagc ttgagctgtt gcaagacccg attttcaagg
    16381 atttcttaga aaaaacatct ctgagagttt atgactttaa gaaggttaaa gttcttttgc
    16441 aacgttttgg tgtggatttg caggcgcctg cttttgacat ccgtttggct aaatacctcc
    16501 tttcgactgt ggaggacaat gaaattgcga ccatcgctag tctttatggt cagacttact
    16561 tggttgatga tgaaactttc tacggtaagg gtgttaaaaa ggccattcct gaacgtgaga
    16621 aattcttgga acacttagct tgtaaacttg ctgttttggt agaaacagag cctattttac
    16681 ttgaaaaact cagcgaaaat gggcaattag agcttcttta tgatatggag caacctctgg
    16741 cttttgttct tgccaagatg gaaattgctg ggattgtggt caagaaagag accttgcttg
    16801 agatgcaggc tgaaaatgag cttgtcattg aaaaactgac tcaagagatt tacgagctgg
    16861 ctggtgagga gtttaatgtc aactcgccta agcagttggg cgtgcttctc tttgagaaat
    16921 tgggacttcc tctagaatac actaagaaaa ccaagacagg ttattcgaca gcagtggatg
    16981 tgttggagcg tctcgctcct attgctccga ttgttaagaa aatcctggat taccgtcaaa
    17041 ttgctaagat tcaatctact tatgtaattg gcttgcagga ctggattttg gctgatggaa
    17101 agattcatac tcgctatatg caggatttga cccagaccgg gcgtttgtct agtgtggatc
    17161 caaacttgca aaatattcct gcccgattgg aacaagggcg cttgattcgg aaggcttttg
    17221 tgccagagtg ggaggatagt gtgctactca gctctgacta ttcacagatt gaattgcgcg
    17281 ttttggcgca tatttctaag gatgagcact tgattaaggc cttccaagag ggggcagata
    17341 tccatacttc gacagccatg cgggtctttg gcattgagcg tcctgataat gtgactgcaa
    17401 atgaccgtcg caatgccaag gcagttaact ttggagtggt ttatgggatt tcagactttg
    17461 gcttgtctaa taatttggga attagtcgta aggaagccaa agcctacatt gatacctact
    17521 ttgaacgttt tccaggtatt aaaaactaca tggatgaagt ggtgcgggag gcgcgtgata
    17581 agggctatgt agagaccctc tttaagcgtc gccgtgagtt gccagatatc aattcgcgca
    17641 acttcaatat tcgtggtttt gcggagcgaa ctgctatcaa ctcacctatc cagggttcgg
    17701 cagcagatat tctcaagatt gccatgattc agctggataa agccttggtt gcaggtggtt
    17761 atcagactaa gatgctgtta caagtgcacg atgaaatcgt ccttgaagtg cctaaatctg
    17821 aattggtaga gatgaaaaaa ttggtgaaac aaaccatgga agaagccatt caactcagtg
    17881 ttcctcttat cgcagatgag aatgaaggag caacctggta cgaggctaaa taaaaagggg
    17941 gctagtcctc cttttttgta gtagaattct gcaaaccttt tcaaaatgtg ctatactgat
    18001 gaaaaaggag gattcctatg agtcaagaat ttatcaatcc aagtgatggc gtgatacgtc
    18061 agtatctcgc aacgagtaaa acccttgctg tggtgggttt gtctgaccgt gaagaaacaa
    18121 ccagcaatcg agtgacaaag gaaatgcagg ctcggggtta taaaatcatc ccagtcaatc
    18181 ccaaggcggc aggtggcgaa atcttgggtg aaaaggctta tgctagcctc gctgaaattc
    18241 cttttcctgt agatattgtc aatgtttatc gtcgcagtga atttctgctc gatgtggcgc
    18301 gtgattttct caaagctgat gccaagattt tttgggcaca gctaggactt gaaagtttaa
    18361 aagcgaaaga gattttgcgt gatggtggat gtgatgatat cgtgatgaat cgctgtatca
    18421 agagagaaca tactcgcttg attgaggaag cataagaaaa aggtagctga tgggctacct
    18481 tttgtgttat actcaatgaa aatcaaagag caaactagga aactagccgc gggctgctca
    18541 aaacaccgtt ttgaggttgc agatagaact gacgaagtca gtaacatata tacggcaagg
    18601 cgacgttgac gtggtttgaa gagattttcg aagagtgtta gaaaatgccg ataagggtct
    18661 gcataccaag agtggtgagg atgatggcaa tccagcagat ggctccaaga agaatggatt
    18721 ttccactgga tttgaccata gcgaccagat tggttttgag accgatagca ctcatggcca
    18781 tgacaataag gaatttagag agttctttga gaggagtaaa gaaactactg gacacaccta
    18841 gagaggtgag tagtgtagtg aggagagagg caaggataaa gtaaaggata aaaagtggga
    18901 agactttttt cagttgcagg ctttgcttgt tttcttgttg gcgactttgc cagtaggata
    18961 gaaagagcgt gatagggata atggccaaag tacgtgtgag tttaacaatg gttgcagact
    19021 cgagggtatt gctttggtaa agactgtccc aagcgctggc ggcagccgtt acagaggaag
    19081 tgtcgttgac cgcagtccct gcaaagaggg cgaagccttc attggataga tgaagccagg
    19141 tgccgagggt tggaaagatg agcgcagcca agacattgaa gaaaaagata acggaaatgg
    19201 cttgggctac ttccttttcc ttagcatcaa taacgggcgc tgtcgctgca atggcagaac
    19261 ccccacagat agaagaacct actccaacca aggtagccag ttttgtatcc agggcaaaga
    19321 aacgctggaa gaggtaggca ataatcagag ctattgagat agtggacagg atgacaggga
    19381 gtgaagattg gccaactgcg aagacctgcg agatattgag accaaagcca agcaagacaa
    19441 cggcatattg gagcaacttc ttggaactaa aggtcaaacc agcatccagt tgtttatagg
    19501 acgagagaaa gggatgtagg agcatgccta tgaaaatggc aaaaacgggc gcgccaatca
    19561 cagggaagaa tcctcctaag taccaagata cgatagaaat gagaaggcag gccaagatac
    19621 ctgctccatt ttttgataga aatgacataa aaacctccaa ataaaatcta ttaccattat
    19681 agacctataa acaggaaaag taaaatagaa agtggaaagc tatcctctaa tgtatttttg
    19741 cggtcggggg gcttttgtag tataatagag atacgttttg aaagtaggag gtatctatgg
    19801 acttaactaa gcgctttaat aaacagttag ataaaattca agtttcgttg attcgtcagt
    19861 ttgaccaggc tatttcggag attcctgggg tcttgcgttt gaccttgggg gaacctgatt
    19921 ttacaacgcc agaccatgtc aaggaggcgg ccaagcgagc gattgatcag aaccaatcct
    19981 actatacagg gatgagtggt ctgctgactc tacgtcaggc agctagtgac tttgttaagg
    20041 aaaagtacca actggactat gctcctgaaa atgaaatctt ggttacaatt ggggcgacag
    20101 aggctttatc tgcgactttg acggctattt tggaagaggg agacaaggta cttttgccag
    20161 ctcctgctta tccaggctat gaaccgattg ttaacttagt tggggcagaa attgttgaga
    20221 ttgatacgac tgaaaatggt tttgtcttga ctcctgagat gttggagaag gccattttgg
    20281 agcagggtga taagctcaag gcggttattc tcaactatcc agccaatccg acaggaatta
    20341 cctacagtcg agagcagtta gaggccttgg cagctgtttt acgcaagtac gaaatttttg
    20401 ttgtctgtga tgaggtttac tcagaattga cctacacagg cgaagcccat gtgtctctag
    20461 gaacgatgtt gagagaccag gctattatta tcaatggttt gtctaaatcg catgccatga
    20521 caggttggcg tttggggctg attttcgctc ctgcggcctt cacatcccag ttaatcaaga
    20581 gtcaccaata cttggtcact gccgcaaata ccatggcgca acatgctgcg gtagaagcct
    20641 tgacgtctgg taaaaatgat gcggagccca tgaagaagga atatatccag cgtcgggact
    20701 atatcatcga aaaaatgact gctcttggtt ttgagattat caaaccagac ggtgccttct
    20761 atatttttgc taaaattcca gcgggctaca atcaagactc ctttgctttt ctgaaggatt
    20821 ttgctcagaa gaaggccgtt gcctttatcc ctggtgcagc ctttggacgt tacggggaag
    20881 gctacgtccg cctatcttat gcagccagca tggagactat caaagaagcc atgaaacgac
    20941 ttgaggagta tatgagagaa gcatgattca gtctatcacg agtcaaggct tggtgcttta
    21001 caatcgcaat tttcgtgagg atgacaagct tgtcaaaatt tttacagagc aggttggcaa
    21061 atgcatgttt tttgtcaaac acgctggtca gtctaagctg gcgcctgtta ttcagccctt
    21121 ggtgctggca cgatttctct tgcgaatcaa tgatgacgga ctcagttaca tcgaagacta
    21181 tcatgaggtc atgacttttc ccaagattaa tagtgacctc tttgtcatgg cctatgcgac
    21241 ctatgtggca gctcttgcag atgctagttt gcaggacaat cagcaggatg ctcccttgtt
    21301 tgcttttttg caaaagactt tggagttgat ggaaacaggc ttggattatc aggttttgac
    21361 caatattttt gaaattcaaa ttttgactcg atttggaatc agcctcaatt ttaatgagtg
    21421 tgtcttctgc catcgggttg gtcaggcttt tgacttttct ttcaaatatg gagcctgcct
    21481 ctgtccagag cattatcatg aggataagag acgttgtcat ctcaatccca atatccccta
    21541 tctgctcaat caatttcaag ctattgattt tgagactttg gagaccattt cgctcaagcc
    21601 tggaatcaag caagagctac gccaatttat ggatcaatta tatgaagagt acgttgggat
    21661 tcacctaaaa tcaaagaaat ttattgattc cctagcagac tggggacaat tactaaaaga
    21721 ggaaaagaaa tgaaaaaaat cgcagtagat gccatggggg gcgattacgc acctcaggcc
    21781 attgttgagg gtgtcaatca agccctatct gacttttcag atatcgaggt tcaactttac
    21841 ggagatgaag ctaaaatcaa gcaatatctg acagcgacag agcgcgtcag cattatccat
    21901 acggatgaga agattgattc ggatgatgaa cctacgagag ctattaggaa taagaaaaat
    21961 gccagtatgg tattggcagc caaggctgtc aaagatggtg aagcagacgc tgtcctttcg
    22021 gctgggaata caggtgcctt gttggcagca ggattcttca tcgtgggtcg tatcaagaat
    22081 atcgaccgtc ctggactcat gtctaccttg cctaccgttg atggaaaagg ttttgacatg
    22141 ctagaccttg gtgccaatgc agaaaataca gcccagcacc tccatcaata tgcggttcta
    22201 ggttccttct atgctaaaaa tgtccgtggc attgcgcaac cacgcgttgg tttgctcaac
    22261 aacggaacag agagtagcaa gggcgacccg cttcgtaagg aaacttatga attactggcg
    22321 gctgatgaaa gtttgaactt tatcggaaac gtggaagcgc gtgatttgat gaatggcgtt
    22381 gcagatgttg ttgtggcaga tggtttcacg ggaaacgctg tgctcaaatc catcgaaggg
    22441 acagctatgg gaatcatggg cttgctcaag acagctatta caggtggtgg tcttcgagcg
    22501 aaactaggtg ccctccttct caaggacagc ctcagaggtt tgaaaaaaca gctcaattat
    22561 tcagatgttg gtggagcggt cttgtttggt gttaaggcac ctgttgtcaa gactcatggc
    22621 tcaagcgatg ccaaggctgt ttatagtacg attcgtcaga tccgtaccat gctagaaaca
    22681 gacgtggttg cccagactgc gcgtgaattt tcaggagaat aaaagagatg acagaaaaag
    22741 aaatttttga ccgtattgtg accattatcc aagagcgaca gggagaggac tttgtcgtga
    22801 cagaatcctt gagtctgaaa gacgatttgg atgcggattc tgttgacttg atggagttta
    22861 tcttgactct ggaagatgaa tttagtatcg aaatcagcga tgaagaaatt gaccaactcc
    22921 aaaacgtagg agatgtggtt aaaatcattc aaggaaaata gcaatcggag ttccaagtca
    22981 acggaagtag atggttttta gaaatgagaa atatcggaca agctggtaaa atcttggctg
    23041 acagtggtta tcaagggctc atgaagatat atcctcaagc acaaactcca cgtaaatcca
    23101 gcaaactcaa gccgctaaca gttgaagata aagcctgtaa tcatgcgcta tctaaggaga
    23161 gaagcaaggt tgagaatatc tttgccaaag taaaaacgtt ta
//
LOCUS       DAVLTT010000027        22074 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLTT010000027 DAVLTT010000000
VERSION     DAVLTT010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.027"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(218..1441)
                     /locus_tag="VYN15_001193"
     CDS             complement(218..1441)
                     /locus_tag="VYN15_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1452512.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKNLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            1609..2931
                     /locus_tag="VYN15_001194"
     CDS             1609..2931
                     /locus_tag="VYN15_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1452513.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            2933..4819
                     /locus_tag="VYN15_001195"
     CDS             2933..4819
                     /locus_tag="VYN15_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV1452514.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYMRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRSYEELIEEYFFALYGENWQSVVEYLEKL
                     SIYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIVEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            4997..5341
                     /locus_tag="VYN15_001196"
     CDS             4997..5341
                     /locus_tag="VYN15_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1452515.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            5351..6763
                     /gene="lacG"
                     /locus_tag="VYN15_001197"
     CDS             5351..6763
                     /gene="lacG"
                     /locus_tag="VYN15_001197"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1452516.1"
                     /translation="MENLQIKALLKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGAPNILAVRYYHR
                     VFQSCLKYNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            6832..8511
                     /locus_tag="VYN15_001198"
     CDS             6832..8511
                     /locus_tag="VYN15_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1452517.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIVWMRKVYMLTMGVLGIIVSGTVGKSLVGNVNRKMPHGKV
                     INDTSAMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLILVVDILIYLPFCRAYDRQLLVKEDIASSNGIILEEDTSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGANLTEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKSLQFVLEHYQAV"
     gene            complement(8639..10078)
                     /locus_tag="VYN15_001199"
     CDS             complement(8639..10078)
                     /locus_tag="VYN15_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1452518.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGNLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(10082..11431)
                     /gene="trkA"
                     /locus_tag="VYN15_001200"
     CDS             complement(10082..11431)
                     /gene="trkA"
                     /locus_tag="VYN15_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV1452519.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVRDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11620..12468
                     /locus_tag="VYN15_001201"
     CDS             11620..12468
                     /locus_tag="VYN15_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV1452520.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12483..13031
                     /locus_tag="VYN15_001202"
     CDS             12483..13031
                     /locus_tag="VYN15_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV1452521.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            13038..13295
                     /locus_tag="VYN15_001203"
     CDS             13038..13295
                     /locus_tag="VYN15_001203"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452522.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            13397..15079
                     /locus_tag="VYN15_001204"
     CDS             13397..15079
                     /locus_tag="VYN15_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1452523.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQAAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNLSIS
                     KGQVQLQNELAKETPALQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            15064..15894
                     /locus_tag="VYN15_001205"
     CDS             15064..15894
                     /locus_tag="VYN15_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1452524.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            16087..16590
                     /locus_tag="VYN15_001206"
     CDS             16087..16590
                     /locus_tag="VYN15_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV1452525.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFMSQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      16644..16878
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            17043..17606
                     /locus_tag="VYN15_001207"
     CDS             17043..17606
                     /locus_tag="VYN15_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1452526.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            17620..18246
                     /locus_tag="VYN15_001208"
     CDS             17620..18246
                     /locus_tag="VYN15_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1452527.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            18274..18663
                     /locus_tag="VYN15_001209"
     CDS             18274..18663
                     /locus_tag="VYN15_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV1452528.1"
                     /translation="MKVNIADLHLTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            18668..19117
                     /locus_tag="VYN15_001210"
     CDS             18668..19117
                     /locus_tag="VYN15_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEV1452529.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKKIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            19245..19832
                     /locus_tag="VYN15_001211"
     CDS             19245..19832
                     /locus_tag="VYN15_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV1452530.1"
                     /translation="MKLEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            20222..21829
                     /locus_tag="VYN15_001212"
     CDS             20222..21829
                     /locus_tag="VYN15_001212"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV1452531.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKVAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT         6584 a         3719 c         4866 g         6905 t
ORIGIN      
        1 tgaataaaaa ttgttattta agttctgggg gttatgatga atgtttttac aataataaaa
       61 tgcagctaga agaaaagtta ttttaatata aatcactcaa catagagaga aggcggtttc
      121 ctatatggaa gtcgtcttgt tttcatattg tctaaatacg agatatttac tacaggttat
      181 agttgattta aacaggtcta tagatttcta atatatatta aggtgaaata atatcttgta
      241 atacattgct atgctctatg aaaaaagcaa cgatagctaa tgcacaagct cctatacttc
      301 cacgatgttt gttgtaaggt aaaatttcaa tttctatatt acgagtaaag ggaacaaagt
      361 ggagttgatc ttggatttta tccctgactt catgagtgaa aggttgataa ttaagcaatt
      421 gactgttgat atagatttta tcagcaggat tgatgaggag aagatttgca atagaagtgg
      481 ccaataaatt gactccttta tcaatttgtt ggcgtaaagc agaatcgcct aagttgtaag
      541 ctgttaaaag agtatctaaa tgaatgtctt tttcagtttt tacaaggttt tttagtacag
      601 ttagttgaga atttttaaat aataattgag catgtttgat taaccaagca tcagaaatat
      661 atgtttgtaa acaacctttt tttccgcatt cacaatattg cccattcaat tcgacaatgg
      721 tgtgtccaat ttctccgata taaggatttt tagaggctcc tattttttct tttgtgaaaa
      781 aggaagtgta aatacctaat ccagcgtgta ggaaaataaa gttatcgggg gtattgtgtg
      841 gattaaaaag gtattgtcct atagccatac aatcgatatt attttttaca ataaaaggaa
      901 aattgaatct tttaattaca tttaataaat taaaagattc ccatatgggg ttgtttgtaa
      961 tgatacttcc ggagtctttg ttataatgtc caggtattga taagccaaat ccaagtaatt
     1021 ttgtctccaa agggacgtac tctatagctg tttttatcat attggtaatg gtggaattga
     1081 tttctgaaat aggataatct tcattcaaaa tttctgtctc gaaaagagtt ttcccttgta
     1141 agtcacatag actgagaaag atacctagga cgtttatttc aatacctcca acaacatacg
     1201 gaatattatc tgtgatagaa atagtttttc tacgtcttcc agatccggaa aactcgctaa
     1261 attcatcacc agtttcgtat atgagggact gttcgcttag ctcttttatg atgttagtcg
     1321 ttgttgctgg agtaagtcct gtttcattaa caatatctgt acgggatgtt gctggatttc
     1381 gatatagaaa ctccagtata gtggctctat tttgtaaaaa ggctgattgt tttgtaatca
     1441 tttgtttcct cctttggttt attttatatt aaacataaga aaaaatcaat taaaattatt
     1501 attctataca aagaaaaaaa tattgtaaaa acaacaaaaa atatattgac aacgctttct
     1561 gttagtggta tatttaattt ataaaaaata aaaaaaggag ttccggtgat gaacaatatt
     1621 ttagcgtttt tagaaacaaa agtcgctccg tttggtgaaa aagttggcaa ccaacggcat
     1681 ttgaaagcta ttcgtgaagg atttatgatg gcaatgcctt tgattttagt cggatcttta
     1741 tttcttattc taatcagttg gcctcaagag gattttacaa attggctgaa tagtgttgga
     1801 ttgctaagta tcttgacaac tatgaatcag tcaacagtag cgattatctc cttggtcgct
     1861 tgtttcggta ttgcctacag gttgtcggaa ggatatggta cagatggtcc gtcggcaggg
     1921 atcatagcct tatccagttt tgtattgatg gcacctcgtt tttcgagtat ggtttatgat
     1981 aaaaatgggg agcaggtcaa gcagttattt ggcggcgcaa taccattttc tagcctgaat
     2041 gcatcttctt tgtttatggc gattactatt ggattggtta cagcagagat ttatcgtatg
     2101 tttatccagc gcggaattac gataaaaatg ccaagtggtg tcccagatgt ggtaagtaaa
     2161 tcattttcag ctcttttacc tggctttact acttttgttt tgtgggctct ggtcttaaaa
     2221 ggtcttgaag cggcaggagt tgcaggaggt ctcaacggac tcctaggtgc aattgttgga
     2281 acaccgctta agttaattgc aggaacgctt ccaggtatga ttctatgtgt tattgtaaac
     2341 tcattctttt ggttctgtgg agttaatggg ggacaagttt taaatgcttt tgtagatcca
     2401 gtttggttac aatttactac agaaaaccaa gaagctgtgg ctgcaggaca aacactccaa
     2461 cacattatta cattaccgtt taaagattta tttgtattta ttggtggcgg tggagcgact
     2521 attggtcttg cgatttgtct cttcctattt agtaagagtc gtgcgaataa aacattaggt
     2581 aagctagcta ttataccgtc tatttttaat atcaatacag ctattctatt tacgtttcca
     2641 acagttttaa atccgattat gctgattccg tttattgcta ctcctacaat caatgcctta
     2701 attacctatg tatcaatggc tgtaggatta gtaccctaca caacaggtgt aatccttccg
     2761 tggacaatgc caccgatcat aggaggcttc cttgcgacag gagctagttg gcgaggagct
     2821 ctattacaag ttgttttgat tttggtttct gtagcaattt attatccatt cttcaaaatt
     2881 gcagataaac gcaatcttga aaaagaaaaa gctactgttg gagggaaata agatggttat
     2941 cagagtattt gatcagcaga aaaatactta ttctagcttt gccttagagg aattaagtta
     3001 ctatataaat cgggtcttta agactgacat agaacttgtc gaggagaagg aagcggatat
     3061 ttttgtagga ttagtcaata aagaggatag aaaagaccat gttcttatct cattagacaa
     3121 gggtaagggg agaattgagt ctaatacaat tgtaggttta cttattggaa tttaccgaat
     3181 gtttcatgaa tttggggttg tgtatactag accagggcgc ggacatgact ttgttccaga
     3241 gttacgattt gaagattttt tagataaaga gctatctata gatgaaacag ccagttacta
     3301 tcatagggga gtatgtatag agggagcaga ttcatttgaa aatatactag atttcattga
     3361 ttggctacct aagattggga tgaacagttt tttcatccag tttgaaaatc cctattcttt
     3421 tttgaaacgt tggtatgaac atgagtttaa tccataccta aataaagaaa aattctcaaa
     3481 tgaattagta caagaattga gtgataggtt ggataaagaa ttgcaaaaaa gaggtcttat
     3541 tcatcatcgt gttggtcatg gatggacagg tgaggtttta ggttactctt caaaatttgg
     3601 ctgggaatca ggtcttagta tttcagagga gaagaaaccc tatgtcgctg aaataaacgg
     3661 gaaacgagaa ttatttaata cggctccgat tttaaccagt ctggattttt caaatccaga
     3721 tgtggcggat aagatggtag aaattatcaa ggattatgcc aagaaaagac ctgatgttaa
     3781 ctacttacat gtatggttgt cggatgctcg taataatatt tgtgaatgcg aaaactgtag
     3841 acaagaattg gtttcggatc agtatattcg tattctcaat caattggata gggctttaac
     3901 gagtgaggga ttagatacaa agatttgttt tctgctttac catgagttgt tatgggcgcc
     3961 tcagaaagaa aaattagata atcctgaacg ctttaccatg atgtttgcac cgattacaag
     4021 aacatttgaa atgagttatg cagatgtaga ttttgacaat tccataccta cgcctaaacc
     4081 ttatatgcgt aataaaatta tacttccgaa ttctcttgag gaaaatttat cttatctttt
     4141 tgagtggcaa aaaacattta aaggagatag tttcgtatat gactatcctt tagggcgtgc
     4201 tcattatggc gatttaggct atatgaaaat tagtcaaact atttacagag atgtatctta
     4261 tctttcaaac ctacatttga atgggtacat ttcgtgtcaa gaattacgtg ccggattccc
     4321 tcataatttt cctaattatg tcatggggca aatgctctgg aagaagacaa gaagttatga
     4381 agaattgatt gaagaatact tttttgcttt gtatggggaa aattggcagt ctgttgttga
     4441 atatttagaa aaattatcca tttattcctc ttgtgactat tttaatgcaa ttggcagtcg
     4501 tcaaaatgat gttttagcga atcattatta tatagcttac aatctagctg ataatttttt
     4561 accaattgtt gaggaaaata tttctaagtt attaaatagt caaaaggatg aatggaaaca
     4621 gctcagttat catcgtgaat atgttgttaa gatggcgaag gctttatatc ttcaagcaac
     4681 tggaaaaaca aggcaagctc aggatgaatg gagaaatgtg ttgaattata tccgtgggca
     4741 cgaattgcta tttcaatcta atttggatgt ttatcgtgta attgaagtag caaaaaatta
     4801 cgctggtttc cacttataaa tcataagtat agaaaatgaa ctaaggtatt cagagaagat
     4861 tgaccctaaa tattatgaaa tttaaggatt tttaaggatt tttaagatat ttagggtcga
     4921 ctttctattt gtatcgtagc gaagtcattt taataatgat gtgtaaaaga tggatcaaga
     4981 ttgaggagga agaaagatga aatcaaaaga agaaataaat atgcttggtt ttacaattgt
     5041 cgcttacgca ggagatgcaa ggtcagattt gatggatgct ttggcgtttg cgagagatgg
     5101 atattttgaa caggcaagag aattggttga gtctgcaaac gactcaatag tgtctgccca
     5161 tcgagaacag actaatttat tagcggagga ggcatctgga gataattttg aagtgagttt
     5221 tatcatgatt catggtcaag atactttgat gacaacgatg ctattgtatg atcaggtaaa
     5281 gttttttatt gatgaatatg aacgaattcg aaagattgaa gaacatattg gtttgcaatg
     5341 aggattagtc atggaaaatt tacagattaa agccttactg aaggagtttt tattaggagc
     5401 tgctaccgct gcttatcaag tagagggtgc aactagggta gatggcaaag gaataaatat
     5461 gtgggatgtt tatttgcaag aaaatagtcc gttcttacca gatccagcta gtgattttta
     5521 ttatcgttac gaagaggata tagctttggc ggcagaacat ggtttgcagg ctttgcgttt
     5581 atctatttct tgggttcgta tatttcctga tatagatggg gcgccgaata tattggctgt
     5641 tcgttattac catagagtct ttcagtcctg cttaaaatat aatgtgattc cgtttgtttc
     5701 tttacatcat tttgattcgc ctcagaaaat gttagaaaca ggggattggt tgaatagaga
     5761 gaatattgat cgtttcatac gatatgctcg cttttgtttc caagaattta cagaagtcaa
     5821 gcattggttt acaatcaatg aactgatgtc tcttgctgca ggtcaataca taggaggtca
     5881 gtttcctccg aatcaccatt ttcaattatc tgaagcaatt caagcgaatc ataatatgtt
     5941 gttggcgcat gctcttgcag tcctcgaatt tcatcaatta gggattgagg gaaaggtagg
     6001 ttgtattcat gctttaaagc caggctatcc tattgatggg caaaaagaaa atattttggc
     6061 agctaaacgg tatgatgttt ataataataa atttctatta gatggaactt ttttgggcta
     6121 ctacagtgag gacacgcttt ttcacttgaa tcaaatattg gaagctaata attctagctt
     6181 tattattgaa gatggtgatt tagaaattat gaagagagct gcagctctta atacgatgtt
     6241 tgggatgaat tattatcgtt cagaatttat tcgtgaatac aaaggtgaaa atagacaaga
     6301 atttaattca acaggaataa aaggacagtc ttcttttaaa ttaaatgctc taggtgaatt
     6361 tgtaaaaaag cctggtattc cgacaacaga ttgggattgg aatatttatc ctcaaggctt
     6421 atttgatatg ttgcttcgta tcaaagaaga atatcctcaa catccggtca tttatttaac
     6481 tgaaaatggt acagccctta aagaggttaa gccagagggc gagaatgata ttattgatga
     6541 tagtaagaga attcgttata ttgagcaaca tttacacaaa gttttagagg ctcgagatag
     6601 aggagtcaat attcaaggct attttatatg gtctttgcaa gatcaatttt cttgggcgaa
     6661 tggctacaat aagcgatatg gtcttttctt tgttgattat gaaacacaga agagatatat
     6721 taagaaaagt gctctttggg taaaagggct aaaacggaat taaggttagc gatttgactg
     6781 atgtttaata tgttttaaat atgaggttga attttttata ggaggagttt tatggataag
     6841 ctagtcgctg ccattgaaaa gcaacaaggg aaatttgaaa aaatttctac taataactat
     6901 atgatggcta ttaaagatgg attcattgct actatgcctt taattatgtt ttcaagcttt
     6961 ttgatgatta ttattatgat tcctaaaaat ttcggagtag agttaccgag tccagctatt
     7021 gtctggatga gaaaagtgta tatgttaacc atgggagttt tgggtattat tgtttcaggg
     7081 actgttggaa agtcattagt tggaaatgtt aacagaaaaa tgcctcacgg aaaggtaata
     7141 aatgatactt ctgcaatgtt ggcagccata tgtagttatc tggtattaac tgtaacgctt
     7201 gtagttgatg agaagacagg atctacaagt ttgtcgacaa actatttagg atctcaagga
     7261 ttgataactt cgtttgtcag tgcctttatt actgtaaatg tttaccgatt ctgtattaag
     7321 cgagacatta ctattcattt acctaaggaa gttcctgggg ctatatcaca agcttttaga
     7381 gatatttttc ctttttcttt tgttttactt attagtggtt tgttagatat tgtatctcgg
     7441 tttagtttag atgttccttt tgcccaagta tttcaacaac tattgactcc tatttttaag
     7501 ggggcagaat catatcctgc tatgatgttg atttggttta tgtgtgcttt gctttggttt
     7561 gttggaattc atggaccatc tattgtctta cctgctgtta cagctttaca actgagcaat
     7621 atggaagaga atgctcaact tcttgcaaat gggcagttcc cttatcattc tttaacacct
     7681 aatttcggga attatatcgc tgctattgga ggaacggggg ctacctttgt tgtaccattt
     7741 attttgattt tctttatgcg gtctaaacaa ttaaaatcgg taggtaaagc tacaattact
     7801 cctgttttat ttgcagtaaa tgaacctctt ctatttggta tgcctgttat tttgaatccc
     7861 tatctttttg tccctttttt gatgactcca ccagtgaatg tatttctagg aaaggtattt
     7921 attgatttct ttggaatgaa tggattttat atccagttac cttgggcctt tcctggtccc
     7981 ttgggattgt taattggaac gaattttcaa cttatctcct ttgtattttt atctttgatt
     8041 ttagttgtcg acatattgat ttatttgcca ttctgtagag cgtatgatag acagttactg
     8101 gtgaaagaag atattgcaag ctcaaatggt attattttag aggaggatac aagtgaaata
     8161 atgcctggtg agttagatga aataaaaagt aaggagttga aagtactggt tctttgtgca
     8221 gggtctggaa caagtgcgca attagccaat gcaattaacg agggggctaa cttaacagag
     8281 gttagagtga ttgcgaattc aggagcgtac ggagctcatt atgatattat gggtgtttat
     8341 gatttaatta ttctggcccc acaagttcgg agttattata gagagatgaa ggtggatgca
     8401 gaaagattag gtattcagat agttgctacc agaggaatgg aatatattca tttaacaaag
     8461 aatccaagta aatccttaca atttgtattg gagcattacc aagctgtgta gtaagttttt
     8521 ccatctttta tttgagtaag gactttgctt acagacaggc ttggatttaa aaacgttccc
     8581 ccttttttta atataagaat ccctcttttt acaattgtaa aaagagggat tttgtatttt
     8641 atctcttaga ccaagttctt ttcataaaga gaaggaggat tgggtaaatc tccaagcgcc
     8701 ctgcaatcat tgcaaaggag aggagaattt ttgagatggg actaaagatt gagaaactag
     8761 aagtggttcc tagaataggc ccgatgttat tgaaacagct aaagacagcg ctggtcacga
     8821 ccagaaaatc attgctatct aggctgacaa taaagataag cgctagcaaa atcatagcat
     8881 agatgacaaa gtacttgaga atcttatgct gggtatcttt atcaatcacc gtttgattca
     8941 catggagggt caaaacacgg tggggcgata ggattgacaa aatttggttt ttggcaattt
     9001 ttgaaaggat gaggcctcga ataatcttga gtccacctgc agttgatcca gcagagccac
     9061 cgattgccat gaggaaaagg aggataaact gggagaagag gggccagttg gtaatatctc
     9121 catatccaaa accagttgtt gtaatgatgt tggaaacctg gaagaaggtc atttcaaagc
     9181 tctttgaaaa ccctgggtag aggtagaggg tgttgaggct aatcaagcct gtagaaacca
     9241 gtacaatgac caagtaagcc cgaagttctt cgtcaccaaa gaaggccttg atgcgacgga
     9301 gcatgaggta gtagtagagg ttgaaattta ccccaaaaac cagaactccg atactgacca
     9361 gataggtaat cagtgagctg ccatagtggg caattccgtc gttatagacg gtaaagcctc
     9421 cagttcccgc tgtccccata gcaatgacaa aactatcgta gagaggcata ccagctagat
     9481 aatagatgat gacaaagagg gagaagagag ctagataaag gagatagaga atctgggcag
     9541 tgttttttag tttggataca accttgccaa aaacaggacc tggaacctca gccttcatca
     9601 cctctaggtg gctatttttg gcattgtcca taatagcaag tgcaaaaaca agcactccca
     9661 tccctccaat caagtgggta aaacttcgcc agaagaggag ggaacggctg agaaccgaaa
     9721 cgtcgttcaa aatacttgct ccagtagttg taaacccaga actaatttca aaaaaggcat
     9781 caataaggct ggggatttgc ccagaaaaga caaaggggag accaccaaag aaagaccaaa
     9841 ggatccaaca gagggcaacg atcaagactc cctccttggc ataaatccgt tgattttttg
     9901 gcttctgtaa attccctgaa ccgcctaaca atacgagaat ccctatggtc gaaaagaggg
     9961 ctgtaaagac ttggctcgat tcacggtaat agacagcgat agccacagga accaagagga
    10021 gaacagcttc aatcaaaagt aactttgaaa ggaggtaacg aatcatactt ttattcattt
    10081 cttacctcgc aatcaagtca taaatcttgg tgatgtttgg caacaaggtt gttactagga
    10141 gcttgtctcc aacttccaac atatcctccc cagttgggaa aatagtcttg ccctttcgaa
    10201 taatggctgc aataagaacc ccttttttca atttcagttg agaaagaggt ttggcagtca
    10261 ttttattggc ttccttgata tggaattgca gggtttcgat ttggccattg gctagatggt
    10321 gcatggcttg aaggtctgaa tactgggcat taactcgacc acgaataaag tgcataatcg
    10381 tatctacagc gatgctttta ggtgtgatga tacttgaaaa atcaggcgca ttgataatct
    10441 cgaggagact ggtacgattg accttagtaa tatttttctg tacacctacc ctgtcaagga
    10501 acatagatgt aatcagattt tcctcatcga ctcctgttag agtcgcaacg gcatcatagt
    10561 gttgagcact ttcttccagc aggatatctt ttgcggttcc atctccttga acgatgtaga
    10621 gatttgggaa tttctcgcta aagaagctgg cgatttcagg attgatttca atgacttttg
    10681 tatcgatacg actatctttg agaataccaa gtagataata ggcaattcta cctgccccaa
    10741 cgatgagaag gctcttcacg gcgcgtgatt taaaataatt atggaagagt atcatatcga
    10801 cacggttacc agtgacaaag attctatctt tatcccgtac agtcatgtca ccgcttggaa
    10861 tgataatttg atgatccctc tctatcgcac agacaatgac attaccaaat tttttacgaa
    10921 aatcagaaat gggcatttgg caaagaccgc tggtggactt gacgacaaat tccatgaggc
    10981 taacgcgtcc accagcaaag cgttcgacag acagggcgtt ggggaagtca atgatattcg
    11041 cgatagcgcg ggcagccaag agctcaggat taacgataag agaaaaaccg agaatattct
    11101 tttccttgaa ataagagtta gaatattcag ggttccgcac ccgaacgata gtttctttag
    11161 ctcccatttt cttggctaga actgctgcaa tcatgttgac ttcatcgtgc tcagtcaggg
    11221 cgataaagat atcacaatct tggacgctgg cttgctcaag aatggcaaaa tcggccccgt
    11281 taccaaggat accaatgata tcaaagcgac tgacaatatg attgagaaca gcttcgtctt
    11341 gctcaatcag caaaacatca tgcttttctg caaccaagga gcgacagagg gcaaaaccaa
    11401 cttttccccc tccgacaagg ataattttca taataaaacc tactttttca tgatgtaact
    11461 atcataccct ttttcaagaa aaaaagcacc tactagctaa taacaagaac ttttagtagg
    11521 aaatttgcta taaggtaaaa ctatacccta accaattgaa atagctatta gcgactttct
    11581 ctgaaatatg gtatgataaa ggatatacaa ggagataaaa tgaataataa tttactggta
    11641 ttacaatcag actttggtct ggttgatggt gcggtatcgg ctatgattgg agtggcttta
    11701 gaagagtctc caaccttaaa aatccatcac ttgacgcacg atatcacgcc ttataatatt
    11761 tttgagggga gctatcgtct ctttcagacg gtggattact ggcctgaggg aacgacgttt
    11821 gtatcggttg tcgatccagg tgtcggttcg aaacgtaaga gtgtagttgc caagactgca
    11881 aaaaatcaat acattgtcac gccagataat gggacgcttt cctttatcaa gaaacacgtt
    11941 ggcattgtag ccattcgtga gatttctgag gtggccaata ggcgtcaaaa cacagagcat
    12001 tcttatacct tccacggtcg tgatgtctat gcctatactg gtgctaaact ggccagtggt
    12061 cacattactt ttgaggaagt agggccagag ctcagtgtgg aacagattgt agagcttcca
    12121 gtcgtagcga ccatcataga agatcatctg gtgaagggag ccattgatat tctggatgtg
    12181 cgtttcggtt cgctttggac ctctatcaca cgggaagaat tttacaagct ggaaccagaa
    12241 tttggtgatc gttttgaagt gaccatctat catgctgata tgctggtcta tcaaaatcag
    12301 gttgtctatg gcaaatcatt tgcagatgtg agaattgggc aacccatcct ttacatcaac
    12361 tctctctatc gtttaggttt ggctatcaac caaggttcct ttgccaaggc ctataatgta
    12421 ggtgtcggtt catcttggac cattgaaata aagaaaatag aaggataaaa taggagaata
    12481 gtatggaaat taaatttaca attaaacaag ttgttgctgt cggaattggc gctgccctct
    12541 ttgttgtcat cgggatgatc aacattccaa cccctgttcc aaatacaagc atacagcttc
    12601 agtatgcggt acaagcgcta ctttctatta tttttggacc gattatcggt ttgcttgtcg
    12661 ggttgattgg tcatgcaatc aaggactctc ttgttggtta tggtttatgg tggacttgga
    12721 ttatcgctag cggactcttt ggtttagttg tgggactttt tagaaagtac gttcgcgtga
    12781 tcaatagtgt ttttgactgg aaagatattc ttatttttaa tctcattcaa ctacttgcaa
    12841 atgcccttgt ttggggtgtc ttggcaccac ttggagatgt tgtgatttat caagaagcgg
    12901 cagaaaaagt atttgcacaa gggattgttg cgggaattgc caatggtgta tctgtagcta
    12961 ttgcaggaac tcttctctta cttgcctatg caggaaccca aactcgtgca ggaagtttga
    13021 aaaaggacta atactcaatg aaaatcaaag agcaaactag gaagttagcc gcaggttgct
    13081 caaaacagtg ttttgaaatt gtggatagaa ctgacgaagt cagctcaaaa catggttttg
    13141 aggttgtaga tgaaactgac gaagtcagta accataccta cggcaaggcg aaactgacgt
    13201 ggtttgaaga gattttcgaa gagtataaaa tgatggggaa ggctgggcaa ctagtctttt
    13261 tcgatgttta tagattagtt aggcaagtaa gctaagatag gaatcttttt ggcgctaaga
    13321 ttttaagaga agagactgca agaagggctt gatttatgat aaaatagaag tctaagaagc
    13381 gaatgaagag agtaagatga aagaagctat aattgagtgg aaggatttct ctttccggta
    13441 tgaaacacaa caagaaccga ccttgcaagg gatagacttg accatttaca agggagagaa
    13501 agtcttaatt gttggaccat ctggatcagg taaatctaca ttgggtcagt gtttgaatgg
    13561 gattattccc aatatttaca agggtcagac atatggagaa tttttgataa agggtcaagc
    13621 agcctttgat atgagcatct atgataagtc tcatctggtt agcacagttt tgcaggatac
    13681 agatgggcag tttattggct tgtctgtggc agaagatttg gcgtttgctc tggaaaatga
    13741 tgtgacagcc ctagatgaga tgaaaggtcg tgtttataaa tgggctgaaa agctggacct
    13801 tcttccttta ctggatcagc gtcctcagga tttgtcaggt ggacaaaagc agcgagtcag
    13861 tctggctggt gtcttgattg atgaaagtcc gattctcttg tttgatgagc cactcgccaa
    13921 tctagatccc aagtcaggtc aggatattat cgaattgatt gaccagattc ataaggaaga
    13981 ggggacgacg actcttatta tcgagcaccg tttggaggac gttctgcatc gccctgtgga
    14041 tcggattgtc ttgataaacg atggtcgtat cctttttaat gggagccctg accagttgct
    14101 tgcgactgat ttattgactc aaaatggaat tcgagaaccc ctttatctaa cgactctccg
    14161 tcaattaggt gtggacttag tcaaggaaga acaattagcg aatctggata acttgtctat
    14221 ctcaaaaggt caggttcagt tgcagaatga actggcaaaa gaaaccccag cattgcagtc
    14281 actctttaga ctagaggaag tatctttttc ttatgatgat agaccgattt taaaatccct
    14341 acatttagat attaaaaagg gtgaaaagat tgctattgtc ggaaaaaatg gagcagggaa
    14401 atcaactcta gccaaggcta taagtagctt tattcagacg gaaggacgct atctttggga
    14461 aaaacaggat ataaaaggcg attctgttgc agagcgggcg gaacgagtag gatatgtgct
    14521 acaaaatcct aatcaaatga tttcaaccaa tatgattttt gatgaggtgg ctctagggct
    14581 ccgtttgcga ggtgtggatg agaaggaaat tgaaacgaga gtatatgaaa ccttgaaaat
    14641 ctgtggactt tatgaattcc gtaattggcc tatttctgcc ctgtcatttg gtcagaaaaa
    14701 acgtgtcacc attgcttcaa ttttggtctt aggagctgaa attattctcc tagatgaacc
    14761 gactgcaggt caagatcaga agaactatac tgagattatg gaatttctcg aagagttaca
    14821 tcaaaaaggg cataccattg tcatgattac ccatgatatg caattgatgc tggattattc
    14881 agaccgggtc cttgtcatgg tggatggaga attgattgcc gatactgttc cagccagtct
    14941 gttgagcgat cctgagctgt tagtaaaagc caatctaaaa gaaacctcca tctttaactt
    15001 ggctaagaaa ctagatgtgg atccactgga tttaacggca ttttacaaag aaaggagaga
    15061 gggatgcaag ctaaattaat cggttaccag catagagata ctgtgattca tcgcttgtca
    15121 ggagctggga aacttctctt tttcattctg gtatcattgg cggccatgat tagctatgat
    15181 accagaatgc tcttgctgat tgccatcttt tcagtctttc tcctctattt atcagaaatt
    15241 cgctttaaag atgtttcctt tgtagccgtt tttgcgacgg tatttgccgt tttaaacgtt
    15301 ttgatggtct atctcttttc tcccgagtat ggggttggac tttatggaga gagaagtgtg
    15361 atttggcagg gaatcggtgt ctacactcta accagccagg agctctttta tctgctaaat
    15421 ttggccatta agtatctttg caccattcct ctggctatta tctttttgat gacaacccat
    15481 cctagtcagt ttgcttccag tttaaatcaa attggtgtgc cctataagat tgcttattct
    15541 gtcagcctga ccttgcgcta tattccagat ttgcaggaag aattctttac tatcaagatg
    15601 tctcaggagg cgcgtgggat ggaattatcc aagaaagctt ctcttatgca acgaatcaaa
    15661 ggcaatctgc tcattattac gcccttgatt tttagctcgc tagaacgcat tgataccatt
    15721 gcgactgcca tggagcttcg ccgctttggg aaagagaaaa aacgcacatg gtatagttat
    15781 caggccttga aaaaaggaga ctatattacc ttgctcttgg caaccttgtt tttagtagtt
    15841 agtttactac ttatcttgca gaatcaggga cgattttaca acccttggaa atagcttgaa
    15901 aaaattgaaa aaatcaagtc atttctattg acaatgattc tgaaagtgtt atactaagaa
    15961 agtagtttcg ctgatttact tcaaacctgt tgtgaggtaa gttaacgatg ccttaaccac
    16021 gctgtttgct gagcttgact ccgggcagtg tggctatttt tttgcaatgg tgaaaggaag
    16081 caagtcatga caaatcacat tgtattattt gaacctcaaa ttccacaaaa tacaggcaat
    16141 atcgcgcgta cttgcgctgc gaccaattct cccctccaca tcatcaagcc tatgggcttt
    16201 cctattgatg accgcaagat gaagcgggct ggattggatt actgggataa gctagagatt
    16261 tatttttacg agagcttaga agatttcatg tctcagatga agggaaaact ctatctgatt
    16321 tcgaaattcg cggaaaaaat ctattctgag gtggatttat cgactgacga ggaccattat
    16381 tttctctttg gacgtgaaga caagggctta cctgaagatt ttatgcgaga acatcctgag
    16441 aaggctcttc gtattcccat gaatgatgaa catgtccgca gtctcaatgt gtctaatacc
    16501 gtctgcatga ttgtctatga ggctcttcgc cagcagaact ttgcaggtct tgaactcgtc
    16561 catacctatg aagtggataa attgaaataa aaaatgaaaa tgaacaaaat gcttgcgctt
    16621 gcaagcgttt tttgttatga taaaagagtc ttcagggcag ggtgtgattc ccgaccggcg
    16681 gtgactttaa ctaggaaatg atcttttcct tttatacttt gttgacaagc tttgcctaac
    16741 cagaagttat gcctacagct tgtcgcctag tctaaaagaa aaatctctat ttccttctct
    16801 ttaaagaagt ccgcgagcgc aagctgatgt ggtgagattc cacaaccgac agtatagtct
    16861 ggatgggaga agacgaaaga atagctttgt ctgttttgat agatttatag ccggattgta
    16921 accacttgct ttgtttttct ttaatagagt aagagggaac ttttgggata taaaaagtga
    16981 gaatagatag aggaatcctt tccaacttct tctgatttta tagaaaattg gaggaacctg
    17041 ttatgacaaa cacacgtcga ctttcgacca ttgcaattct atcagccatc tcatttgtgc
    17101 tgatgtactt tgactttccg cttttaccag cggcatcttt cctcaagatc gaatttagta
    17161 tcttgccagt ccttgttggt ctggtggtca tggatttgcc tgctgctcta ggagtgctct
    17221 tgcttcgctc actattgaaa ttgcttctta acagccaagg agtgaatact tacattggtt
    17281 tgccgatgaa tatcgtagct ttgggagttt ttgtcatcgt atttgctttg atttggaaaa
    17341 aggaacggac aacccttcgt ttcctactag gctctctagc tggaactgtt ggtttaacct
    17401 tggccatgtt ggttctcaac tatgtttatg ctgttccttt gtacgctaag tttgctaact
    17461 ttgatattgg aaaaattttg ggactttcca actacctaat gaccatggta ttacctttta
    17521 acttgattga gggtgtaatc ttttccgttt cattctggtt gttgtacgtc cttttgaaac
    17581 caaccttaaa acactatgaa agataaacaa acatttttaa tgaagggcag ttttgccctt
    17641 ttacttttcg ttattcttgg ctatatggtc aaattttacc ctgaaatgtt ggtcaatttt
    17701 gaccaatcga ttcagactgc cattcgagga gacttaccag attatttgac tattcttttt
    17761 cgagccctca cacgtctgat tgatatccca gtgattatca cttgggttgt tattacagct
    17821 tttgtctttt atcgtaagcg atggaagata gaaagtttct tcatgctggg aaatctggct
    17881 ttggcaggtc ttttaatcgt gacctttaaa aatatctacc agcgcccacg accagctatt
    17941 ttacatctgg tggaggagaa gggattttcc ttcccaagtg ggcattctct agctgtaacg
    18001 ctgatggtag ggactttgat tgttattctt agtcagcgga ttaaagatca ggtctggaga
    18061 aaaatcgtac aaatcgtcct tggcctctac ctagtcagtg tgctggtatc aagagtctat
    18121 ctgggagttc attacccatc agacgtcctt gccagtctct gtgtgggctt gggagtcctg
    18181 tttatcgagt ttccctttta tgacaagctc cgcttccaat ggcgatttaa aggcaaacag
    18241 aagtgagtat cgaattccct tgaggagaaa gaaatgaaag tcaatatagc agatcttcat
    18301 ctgactcaac tatatttatc agaaaagaag ttgcaagata ttcagatgct ttaccagtcg
    18361 gcagaaacaa tccaagtcga tccaatcagt attcttgcct ttggagattg tttgctgatt
    18421 acagatgggc atcacagggc ttatcaggct ttattggcag gtcgggatac gatttctgct
    18481 gagtgggata gagatggtgg tgatgaacta tatcatctct atgcgcaagc ttgcgaggaa
    18541 agaaagattt actctgtttt tgatttagaa gatcgtatcc tagctcaaga tgggtatgaa
    18601 gcaaaatggt ataactggtg tgatggtttt aatcaagcag caactctttt gttgaaaagg
    18661 tagtgcattg tgttttgttc cttattataa ggtcaatcat tgtgaggaag cttttgcttg
    18721 gtatcaggat gtgaacttgg tttacctcgt agatggggtg aagcttcctt acagtcaagc
    18781 gaccttggaa gccatgtatt cctatttgga tcggcatggt gagctttttt ggattgaagt
    18841 caaggagaag ggagaatggt ttccaattgg ggatattaca ctatctcagg ataatctccc
    18901 cattgtgatt gggaattccg cttaccaaca tcgaggactt ggaaaaaaga ttctaagtgc
    18961 tttgattgaa ttggctcgag taaaaggatg gaaagaattg agagtcaaga aaatctacac
    19021 ctacaatcat gcttctagga ggtgtttcaa gtcgcttgga tttgtggaaa atggagcaac
    19081 agaaaaagga atgagtttta tattggaatt agtctaatcc tgccactttc tcccccttaa
    19141 cctttgacta ttccgcaaaa ttatcgtaaa ataaagagta aatgataaaa tgaggtcaga
    19201 gtctgttcgc tctggcgata gtagtataaa tgaggagaaa cgctttgaaa ttagaagtat
    19261 ttgctgggca agaaaaaagt gaactatcta tgattgaggt agcgcgtgct atcttggaac
    19321 ttcgtggtcg cgatcatgag atgcatttta gcgatcttgt aaacgaaatt caaaactacc
    19381 ttggaacatc aaacagcgat atccgcgaag ctttgccttt gttctacaca gagttgaact
    19441 ttgacggtag cttcatctca cttggggaca acaaatgggg tcttcgttca tggtatggtg
    19501 tggacgaaat cgacgaagaa atcatcgctc ttgaagaaaa tgacgacgat gaagtagcac
    19561 caaaagctaa gaaaaaacgt gtcaatgcct ttatggatgg tgattcagat gccattgact
    19621 acaatgcaga tgatccagaa gacgaagatg catacgaagc agatccagct ctttcatacg
    19681 atgatgaaaa tccagatgat gaaaaaaatg aagtggaagc ttatgatgca gaaatcaacg
    19741 aaatcgctcc agatgacttg ggagaagatg tggatctcaa cgaagacgac gacgagtttt
    19801 cagatgacga cgctgaaacc agcgaggaat aagagttagc tattgacaat tatcctattt
    19861 ttaggtatca tattgtttgg gcacctcttt tagaggtcgg ggctccctag ttcttaggga
    19921 gctatttttg ttttttcaag aagttatctt cttgtatttt atactcaatg aaaatcaaag
    19981 agcaagctag gaaactagcc gtaggctgct caaaacactg ttttgaggtt gtagataaga
    20041 ctgacaaagt caggaacaca tatctacggc aaggcgacgt tgacacggtt tgaagagatt
    20101 ttcgaagagt attagttgtg aatctggtgc agtcgtccca gattattctt attagtaggg
    20161 tcttgttttc tatatcccct cgtagttaac aagaccttga gcattttaga aagaggaatc
    20221 tatgtctacg aaatatattt ttgtaactgg tggtgtggta tcgtctattg ggaaagggat
    20281 tgtggcagcg agtctaggcc gtctcttgaa aaatcgtggt ctcaaagtaa ccattcaaaa
    20341 gtttgaccct tatatcaata ttgatccggg aaccatgagt ccttaccagc acggggaagt
    20401 ttttgtgaca gatgacggag ctgagacaga tttggacttg ggtcactatg aacgtttcat
    20461 cgatatcaat ctcaacaaat attccaacgt gacaactggg aaaatttaca gtgaagttct
    20521 tcgtaaagaa cgccgtggag aataccttgg ggcaactgtt caagtcattc ctcatatcac
    20581 agatgctttg aaagaaaaaa tcaagcgtgc cgctctaacg accgactctg atgtcattat
    20641 cacagaggtt ggtggaacag taggagatat cgagtccttg ccattcctag aggctcttcg
    20701 tcagatgaag gcagatgtgg gtgcggataa tgtcatgtat atccatacaa ccttgcttcc
    20761 ttacctcaag gttgctggtg aaatgaaaac caaaccaacc caacactctg tcaaagaatt
    20821 gcgtggcttg ggaatccaac caaatatgtt ggttattcgt acagaagagc cagctggtca
    20881 aggaattaaa aataaactgg cccagttctg tgatgtggca ccagaagccg ttatcgaatc
    20941 gttggatgtt gaacaccttt accaaattcc actgaacttg caggcacaag ggatggacca
    21001 aattgtttgt gatcatttga aattagacgc accagcagcg gatatgacag aatggtcagc
    21061 catggtggac aaggtcatga acctcaagaa acaagttaag atttcccttg ttggtaagta
    21121 tgtggagttg caagatgcct atatctcagt ggtcgaagct ttgaaacact ctggctatgt
    21181 caatgatgca gaagttaaaa tcaattgggt caatgccaat gatgtgacag cagagaatgt
    21241 agcagaactc ttgtctgatg cggacgggat catcgtacca ggtggttttg gtcaacgtgg
    21301 tacagaaggg aaaatccaag ccatccgcta tgcgcgtgaa aatgatgttc caatgttggg
    21361 agtctgcttg ggaatgcagt tgacatgtat cgagtttgct cgtcacgttt taggtcttga
    21421 aggtgccaat tctgcagagc ttgcaccaga aacaaaatac cctatcattg atatcatgcg
    21481 tgatcagatt gatattgagg atatgggtgg aacccttcgt ttgggacttt atccgtctaa
    21541 gttgaaacgt ggctctaagg ctgctgctgc ttatcacaat caagaagtgg tgcaacgccg
    21601 tcaccgtcac cgttatgagt ttaataatgc cttccgtgag cagtttgagg cagcaggttt
    21661 tgtcttttca ggagtttctc cagacaatcg tttggtagaa atcgtggaaa ttcctgaaaa
    21721 taaattcttt gtagcttgtc agtatcaccc tgaactgtca agccgtccaa accgaccaga
    21781 agaactctac actgcctttg ttactgcagc ggttgagaac agcaattagc aaaatcagaa
    21841 cctttgagaa aaatctcaga ggttttttgc atacgatgat attgcagtat atctgaggta
    21901 ggggtcctct gtatgtacct gctaccgttg aaatcaatag cgactccctc ttgccctgtg
    21961 ctagtgaatg gatttatcag tatattgaaa tgaaataaaa tttgaacaaa ttaattcgga
    22021 aagccaaatc aatttctagc aaagttttag gaactggatt gtatagtgaa ttga
//
LOCUS       DAVLTT010000028        21983 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLTT010000028 DAVLTT010000000
VERSION     DAVLTT010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21983
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.028"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(176..373)
                     /gene="blpI"
                     /locus_tag="VYN15_001213"
     CDS             complement(176..373)
                     /gene="blpI"
                     /locus_tag="VYN15_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEV1452532.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            655..1242
                     /locus_tag="VYN15_001214"
     CDS             655..1242
                     /locus_tag="VYN15_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV1452533.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            1169..2812
                     /locus_tag="VYN15_001215"
     CDS             1169..2812
                     /locus_tag="VYN15_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1452534.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2823..4184
                     /locus_tag="VYN15_001216"
     CDS             2823..4184
                     /locus_tag="VYN15_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV1452535.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ETQLQRFEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLLLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            4241..4369
                     /gene="blpC"
                     /locus_tag="VYN15_001217"
     CDS             4241..4369
                     /gene="blpC"
                     /locus_tag="VYN15_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV1452536.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(4440..5780)
                     /locus_tag="VYN15_001218"
     CDS             complement(4440..5780)
                     /locus_tag="VYN15_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1452537.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLLKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(5794..6531)
                     /locus_tag="VYN15_001219"
     CDS             complement(5794..6531)
                     /locus_tag="VYN15_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1452538.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(6536..6874)
                     /locus_tag="VYN15_001220"
     CDS             complement(6536..6874)
                     /locus_tag="VYN15_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1452539.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7150..7479
                     /locus_tag="VYN15_001221"
     CDS             7150..7479
                     /locus_tag="VYN15_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1452540.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDLRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7647..8696)
                     /locus_tag="VYN15_001222"
     CDS             complement(7647..8696)
                     /locus_tag="VYN15_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1452541.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     QVLYLPYQVKRQMQD"
     gene            complement(8693..9424)
                     /locus_tag="VYN15_001223"
     CDS             complement(8693..9424)
                     /locus_tag="VYN15_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1452542.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVADPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9492..9902
                     /locus_tag="VYN15_001224"
     CDS             9492..9902
                     /locus_tag="VYN15_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1452543.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9912..10199
                     /locus_tag="VYN15_001225"
     CDS             9912..10199
                     /locus_tag="VYN15_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452544.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(10889..12025)
                     /gene="dnaJ"
                     /locus_tag="VYN15_001226"
     CDS             complement(10889..12025)
                     /gene="dnaJ"
                     /locus_tag="VYN15_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV1452545.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12427..12783)
                     /locus_tag="VYN15_001227"
     CDS             complement(12427..12783)
                     /locus_tag="VYN15_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV1452546.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQAGNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(12785..14608)
                     /gene="dnaK"
                     /locus_tag="VYN15_001228"
     CDS             complement(12785..14608)
                     /gene="dnaK"
                     /locus_tag="VYN15_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV1452547.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAVQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(15088..15612)
                     /gene="grpE"
                     /locus_tag="VYN15_001229"
     CDS             complement(15088..15612)
                     /gene="grpE"
                     /locus_tag="VYN15_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV1452548.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSKLDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDAIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15639..16673)
                     /gene="hrcA"
                     /locus_tag="VYN15_001230"
     CDS             complement(15639..16673)
                     /gene="hrcA"
                     /locus_tag="VYN15_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV1452549.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16837..17274)
                     /locus_tag="VYN15_001231"
     CDS             complement(16837..17274)
                     /locus_tag="VYN15_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV1452550.1"
                     /translation="MHLKGWRYRTSRFGLFYFDQCQPDDVIYRIYDSRFLKKYKHELQ
                     DFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMSKGLKWEVMRSRLRSCTTTFLGGLV
                     VCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFRLKRKYRVDE"
     gene            17954..20287
                     /locus_tag="VYN15_001232"
     CDS             17954..20287
                     /locus_tag="VYN15_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1452551.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLMYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKEDSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDKEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20300..21763
                     /locus_tag="VYN15_001233"
     CDS             20300..21763
                     /locus_tag="VYN15_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1452552.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTNDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21763..>21983
                     /locus_tag="VYN15_001234"
     CDS             21763..>21983
                     /locus_tag="VYN15_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HEV1452553.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADG"
BASE COUNT         6985 a         4465 c         4049 g         6484 t
ORIGIN      
        1 accaatccat caactaagta aagcatcaac gattacataa acgattgata atataattaa
       61 aattttgcta actatcttat tctcatgatt cttagataac tttgatattt tgtaagtaag
      121 taaataagac agtaaattaa tagcgataat aatactatat ttaagaatca taatcttaca
      181 aagaggacat aattcctgaa cctacacaaa taagtgttgc tgctccccca gttatcggac
      241 cagtcgcagc agctaatagt actgctccaa tacaaccacc gattgcagat cctaaattgc
      301 ctcttcctcc actaactatt tcgagttctt cattatccat aacagaaaat tgttccatca
      361 tttttgtatt catgacaaat actccttttt tcttttttta tttttgtctt gttgtaactt
      421 tgataagttt agtatatcat cgttttttaa aatttttcat ccagatcttg aattgtcatc
      481 gaaacgtctt gaattaggtt ttttatttca agccacctct aaatgtttaa aaaaaataat
      541 ttctaatcac ttttttacca ttcaggaagt tttaatgact attcaagatt tcataaaata
      601 tgaacttagt tttatgacat aatagaccta tccactatat gaaaggaatt gccaatgact
      661 tcttataaac gtacatttgt tcctcaaata gatgcgagag actgtggtgt cgctgcctta
      721 gcctcgattg ctaaattcta tggttcagat ttttctctag ctcacttgag agaacttgca
      781 aagaccaata aagaagggac gactgctctt ggcattgtaa aagccgctga tgaaatgggc
      841 tttgaaacaa gacctgttca agcagataaa acgctctttg acatgagtga tgtcccctat
      901 ccatttatcg ttcacgttaa caaagaagga aaactccaac attactatgt tgtctatcaa
      961 acaaagaaag actatctgat tattggtgat cctgaccctt ctgtaaaaat cactaaaatg
     1021 tcaaaagaac gctttttcta tgaatggact ggagtagcta tttttctagc taccaaaccc
     1081 agctatcaac cccataaaga taaaaagaat ggtctactaa gcaagcttcc ttcctctgat
     1141 tttcaaacaa aaatctctca ttgcttacat tgttctctca agcttattgg tcactattat
     1201 caatataggt ggttcttact atctccaagg aatcttggat gaatacattc caaatcagat
     1261 gaaatcaact ttaggaatca tctcagttgg tctggttatc acctatatcc tccaacaagt
     1321 catgagcttc tccagagatt atctcctaac cgttctgagc cagagattaa gcattgatgt
     1381 gattttatcc tatattcgcc atatttttga acttcccatg tctttctttg cgacacgtcg
     1441 tacaggagaa atcatttcac ggttcacaga tgctaactct attatagatg ccttggcttc
     1501 taccattctt tctctttttc tggatgtttc tattctgatt cttgtagggg gagtcttgct
     1561 ggcacaaaac cctaatctct tcctcctttc tcttctttcc attcctatat acatgttcat
     1621 catcttttct tttatgaaac ctttcgaaaa aatgaaccat gatgtcatgc aaagtaattc
     1681 tatggttagc tctgccatta tcgaagatat caacgggatt gaaactataa agtcgctcac
     1741 gagtgaagaa aatcgctatc aaaatataga cagcgaattt gtagattatt tggaaaaatc
     1801 ctttaagctc agtaaatatt ctattttaca aacgagttta aagcagggaa caaaattagt
     1861 tctgaatatc cttatcctat ggtttggcgc tcaattagtc atgtcgagta aaatttctat
     1921 cggtcagttg attaccttta acacacttct ttcttacttt acaactccta tggaaaatat
     1981 tatcaacctc caaaccaaac tccaatctgc gaaggttgct aataaccgtt tgaacgaagt
     2041 ctatctagtc gaatctgaat ttcaagttca agaaaaccct gttcattcac attttttgat
     2101 gggcgatatt gaatttgatg acctttctta taagtatggt tttggacgag ataccttaac
     2161 agatattaat ctcacgatta aacaaggaga taaggttagc ctagttggag ttagtggttc
     2221 tggtaaaaca actttagcca aaatgattgt caatttcttt aaaccctaca aagggcatat
     2281 ttccatcaat catcaggata ttaaaaacat tgataaaaaa gtcttgcgcc gtcatattaa
     2341 ttacctaccc caacaagcct atatctttaa tggctctatt ttggaaaact taaccttggg
     2401 cggtaatcat atgattagcc aagaagatat tctaaaagct tatgaattag ctgaaattcg
     2461 tcaagacatt gaaagaatgc ctatgggcta tcaaactcag ctctctgatg gagctggtct
     2521 atcaggagga caaaagcaac gaatcgctct cgctcgtgct cttttaacta aagctcctgt
     2581 tttaatacta gatgaagcta ctagcggtct tgatgtcttg actgagaaaa aggttataga
     2641 taatcttata tccctaactg ataaaaccat tctctttgta gcccatcgtc tcagtatagc
     2701 cgaacgaact aaccgtgtca ttgttcttga ccaggggaaa atcattgaag ttggtagtca
     2761 ccaagagtta atgcaggcgc aaggcttcta ccatcatctg ttcaataaat aaggagaatg
     2821 tcatgaatcc taatcttttt agaagcgtcg agttttatca gagacgttac cataactacg
     2881 cgacagtgtt cattatacct ctttcattac tgtttacttt catcttgatt ttctcccttg
     2941 ttgccacaaa agaaattact gttacttccc aaggggaaat cgcccctaca agtgtcattg
     3001 catctattca gtcgaccagt gataatccta tccttgctaa tcatttagtg gcaaatcaag
     3061 tagttgagaa aggtgactta ctcatcaaat actctgaaac aatggaagag agtcagaaaa
     3121 ctgccttaga aactcaatta caaagatttg agaagcaaaa agaaggactt ggaattttga
     3181 aacaaagctt agaaaaagcg actgatcttt tttctggcga ggatgaattt ggctaccata
     3241 atacctttat gaattttact aaacaatccc atgatattga actgggtatc acaaagacta
     3301 acactgaagt ttcaaatcaa gccaatcttg ccaatagcag ttcatcagct attgaacaag
     3361 aaattacaaa agttcaacaa caaattggag aatatcaaga gctgagagat gctatcataa
     3421 ataacagagc acgcttacca actagcaatc cacaccagtc aattttaaat cgttatcttg
     3481 tagcctcaca aggacaaaca caaggaacgg cagaggagcc atttttatct caaattaatc
     3541 aaagtattgc aggtcttgaa tcatctatcg caagcctcaa aattcagcaa gctggtatcg
     3601 gaagtgtagc aacttatgat aatagtttag caaccaaaat tgaagtactc cgcactcaat
     3661 ttttacaaac agcttctcag caacaactaa ccgtggagaa tcaattaaca gaattaaaag
     3721 tacaactaga tcaagcgaca cagcgcttag aaaataatac cttaaccgct ccaagtaaag
     3781 gtatcgttca tctgaacagc gaatttgaag gtaaaaatag aattccaact ggtacagaaa
     3841 ttgctcaaat attccctgtc atcacagata caagagaagt actaatcact tactacgtat
     3901 catctgacta tctcctctta ctagataaag gacaaactgt aagattaaaa ctggagaaga
     3961 ttggaaatca cggcaccacc atcatcggtc aacttcagag tattgatcaa actcctacca
     4021 gaacagagca aggcaatctc tttaaattaa ccgctcttgc aaaactatct aacgaggata
     4081 gtaaactcat ccaatatggc ttacaaggtc gcgtcactag tgtaactaca aagaaaacat
     4141 attttgatta tttcaaagat aaaattttaa cacattctga ttaattttca gataacactc
     4201 tataactatt tattatctta tcaaaaagga gaatcataac atggataaga aacaaaacct
     4261 aacttcattt caagaactaa caactaccga actcaaccaa attacaggtg gaggattgtg
     4321 ggaagattta ttatataaca ttaatagata tgctcattac atcacataag aacttcatca
     4381 tccaatacaa ctataaaaaa ataagaccga gaaacaagta ctctcggtct tatttttcat
     4441 cattctgtat gtatcacagt aagtacctga cgaaagactt gattttgaca ggtggtattt
     4501 agactggtat taggatggct ttccacaatc ttcatgacgg tatagagacc aactcctctc
     4561 tcctcccctt tagaactggc tccaaaggag aagatttcag aaatatcgat gccctcttct
     4621 ttgatggagt tttcgatgat aaaggtctcc tgtgctccat tttttaaaaa ggcgattgaa
     4681 acatgaggtt gactagcttc cacactggct tcaatagcat tgtcacaaag gatagacaca
     4741 atggttagaa aatcaagtag actcatcccc tcgacctgaa tctcctcagg aacttcgaca
     4801 ttaaagacaa tgttcttatc tctggctttt aaaaatttcc ctgctagaag acttttgagg
     4861 gctttatcac gaatatttac caatctgccc aggtcatatt tattgttctg caatttctga
     4921 ctggaatcct ttaagacgga gccatagacc tcttttatct gctccatatc ctcctcttca
     4981 atgcccagac gtaagctagt caagaggttg gtataatcat gacgaaagct ccgtacttcc
     5041 ttgtaaagct cctctatatg ccgactatag cgttccatat ctctatagcg cagggcctgc
     5101 tcttgttcca atctctcata gagtttttcc ttcaaatagg tatccaattt cttgataacc
     5161 cccataaaaa agagtaggta aaagactagg atgagatggc gaacagtctt tgattgaata
     5221 ctttgttcat attcaaaaaa agacagactt tccatgacta gatagtagcc acccattatc
     5281 cagttaatct gagtcaggga cttttgaaag gctttatcga gaatctcctt tctcaagcta
     5341 gtaaaatcgt agtccaacca tttcaaaaaa gctagagaaa tgaagaaatt gaaaattatt
     5401 atacataacc cagtaaatga gtagccatca tatacttgcc cttgtcccaa aaatggaagc
     5461 acaaaatagg agactcctct ataaaagaga ttcaccaata tcattggaaa gagaccataa
     5521 aagaaaagga gttttttagg aagccctctc aataataaga aagataagcc tatgccgtac
     5581 aagggttcca taaaataaga taggtaaaca tttcctacta tatagctaat catcacaaaa
     5641 acaaaggcca acagtatctt caaaagaaag gccttaaaaa tcctctcgaa agtaagatca
     5701 attccatcca ccttaaagaa gatgacaatt tctagtccat tagtaacaag tgtatacaac
     5761 aatatccaag caatgttcat aaattctcct agctcagtgt aatttattga tggcctcaga
     5821 cacttccctg accttataac gggcgattag acaacttcca ccattgggaa agaaaagcag
     5881 tttttctttc ttatccaaat gcaccacatt tgcaggattg atgagaaaag agcggtggca
     5941 ctgcaagaga cggggctcct gcttgaaaac ctcctctaaa ctcgctgtaa attccagcct
     6001 gtctgtcttg gtatagagaa taacacgatg ggctctgggc gacgtttcga gatagtaaac
     6061 ctctttaaaa ggatactgaa attgggcaaa ttttgattta aagtaaaagc aatcttccgc
     6121 cagactttta ctatcttgac tattggcata gaggagggct gtctcgatcc gagattcaaa
     6181 ctcctctgct gacaaggcct tatcaatgta gtccaaagca gacacttggt agcgaaaaga
     6241 caggggcata aactccgagt gagtcgtcac aaagacaatc agggcataag gatcccgatc
     6301 ccgaatcttt ctagccactt ccagtccctt catctcttca tttcgaatct caatatccaa
     6361 aaagaatagc tgatgggccc ccttctcatg cacttcagcc agcagttggt ccggcttgcc
     6421 aaatacctca aaagagctag gaatgatatg atgtgctttc aaaagtttct caatcgtcgt
     6481 ttcaattcta gtctgttggg aaaaatcatc ctctaaaaca aatattctca tcttcttact
     6541 ctccctcttt caaccatttt tgacgaattt ctctatagcg acgtctggca tacttgacag
     6601 cgtattgacc ttcttctccg agaaaaagga ttctttcttg aaaatcaatc gattttaatt
     6661 tatcaagatt aaccaaacaa tttcgatgac atctcatcaa ggtttcccca cattggttct
     6721 caagattact taaattttga agcatattaa aactagcttc ttctgtaaca atctgtacgg
     6781 tatgggcttt agttggatgt gtttggatat agtagatatc gtcgatgttt actttataga
     6841 ctgttttctg cgtctgaata atcatatgtt tcattggatt ctcctcctaa gaaaagaata
     6901 acagaaaagg tctagcccaa gcacacccaa tcctaaacag tctttgaaaa ctcctaaaag
     6961 gattattttc tacaacatca tgatgagctt acaactattt tatcataaaa ttcactcagc
     7021 gcaattcaag acatttcaat gacaattaaa gatttgaata aaaaaaaaga attaaaagtg
     7081 ataaactaac agtatcaaaa cacagttgcc agaagtaaga ctggcaccca gattaaagga
     7141 ggcattccca tgacagatac agaccccatc aaaagagctc atactttgat tactgactta
     7201 aacaaagcct accaagcatg caaacaggca agcgctgacg acctccgctt tcaggagcaa
     7261 ttaaactcta ttcttggttt tctagccaag gctgaaacag tggataatcg attcttgatt
     7321 gaattggaaa aattttacca gacttccagt cttctcatgg gactcagcgc tcttgatcca
     7381 gatgctccaa ctcgcgccgc ttggcgggcc tatgaccgct tccactttga ccaagtcaag
     7441 accaagttaa tactcaatga aaatcaaaga gcaaactagg aagctagccg caagctgtac
     7501 ttgagtacgg taagacgacg ctgacgtggt ttgaagagat tttcgaagag tataagtctc
     7561 tacggaccaa ccattatcct gtagtaacaa aaaagaagct gagacagact gaactcaact
     7621 tcttttttag tgtcgtatca gcaatgttag tcctgcatct gacgttttac ctgataaggc
     7681 aaatacaaga cttgtaaaac caaaccagct cccagtaagg ctagaagggc tagtttttct
     7741 tgaaaggtaa tcaacccaac aactaattcc acaagtaaaa caaaactggt caatcctcga
     7801 actacctcct gtaagccttt ttccttttgc cccttgtcca gcggaaagag ttgggtcaaa
     7861 tactggtagt caaaggcatg atagagggcc agcaactgga agagcaagag gtagttaaag
     7921 agaactacca ctgctgtcgc aatccaagct tgctcgataa aaacctgcgc cagtacggaa
     7981 agtaagagaa gacgaagact gagagcaaag aggtcgccat ttcgcagata agaacgcaga
     8041 tagagatttt gccaaatctt cccaggcacc ttctgaacag cctttaagat aaagtccaga
     8101 taggcacgac gcttaacgct gtttgaaatt cccttgacct gcgtaaagag ggcaaagaaa
     8161 cgaagcaaga cttgcttacg cttgctttct tgagaaataa catagtccca atccagtcca
     8221 gtttcagtga aaaatttgct ggccttttga cgaaagtgga aatattttcc tacccccaat
     8281 aaaagcacat agagcagaaa aactggcaag ccataaccca ttgctaaaaa taaaggcgca
     8341 aataacagca agaaaagggt ctgtacaaag agccaaaaga ctagggaaat gccagtttga
     8401 cgcttgagat ggagcttgat ttcctcttct ccaactaaga gaaagagctt gtctggagcc
     8461 tccatatagg tggcaattcc tccccaaagt aaaagtaaaa cagacgtaat tcctacaaac
     8521 aaaaggatag gccaatgatt ttcaggaaaa tgttgtaaga gttgactgta ctggtaggct
     8581 agaaagccca acaggacaag caggaacaag acaaagtggt cattgagcac atagcgcaga
     8641 taaccaagac actccttacg aaaggcctgc tttctcttta aaaacaagtc tttcataggt
     8701 cctcctcttt tgtcagagcc aagtaaatat cattcaaact agcctcaggc atatcaaagg
     8761 cttcgcgtag ttgcaggaga ttgcctttgg cacgcacctc tcccttgtga agaatgacaa
     8821 aggcatcaca catcttctcc gccgaatcca gcacgtgggt actcatgaga atagacttgc
     8881 ccttttgctt ctccacttcc aaaagctgaa tcaaatcaga aatagccagc ggatcaagac
     8941 caaggaaagg ctcatccacg atgaaaagac ttggatccgc cacaaaagca cagataatca
     9001 tgaccttctg cttcatccct tttgaaaaat gaacagggaa ccagtctaat ttctgttcca
     9061 aacggaacat ttttaacaag ggctctactc gttcgaaagc cactttttgc tcaataccgt
     9121 aagccatagc aaccgtttcg atatgctctc tgagggtcaa ttcctcatac agactaggcg
     9181 tctcaggaat gtagccaatc tgcttgcggt agctagtcgc atctccttgc agagtcaggc
     9241 cattgatatt gatggagcca ctataaggtg ccaacagacc gataatctca ttgatcgtcg
     9301 ttgatttccc agcaccattg agaccaatca aaccgaccaa ctgcccactt tcaacagtaa
     9361 aggacacatc tttcaaaaca ggaacatgaa catagccacc tgtcaggttt ttaatttcta
     9421 acatattttc tccaaatctg gtataatgta gctatattat atcaaaattc agtacagtag
     9481 aggtagattt tatgtcagat tgcatttttt gtaaaatcat cgcaggggaa attcctgctt
     9541 caaaagtata tgaagatgag caggtccttg cctttcttga tatctctcaa gtaacactag
     9601 gacacacctt ggtcgtgcca aaagaacact atcgcaatct tttggagatg gatgctacga
     9661 gcgccagcca actctttgcc caagtaccaa aagtagctca aaaagtcatg aaagtcacta
     9721 aggctgctgg tatgaatatc atttccaact gtgaagaagt cgctggtcaa acagtttttc
     9781 atactcacgt tcaccttgta cctcgctaca gtgctgacga tgacctcaag attgatttta
     9841 tcgcccacga accagacttt gacaaacttg ctcaagtcgc tgaaaccatc aaaaacgctt
     9901 aaggagttgc tatgaaatta tccaacctac tgctatttgc aggagctgca gccggaagtt
     9961 atctggtcac aaaaaatcgc caaaccatca cagatgaagt cttgaatacc actgaccgcg
    10021 ttcaagctat caaggacgat gtggatatta tccaaaacag cctgcaaatc attgaccagc
    10081 aaaaagaact tatcaaggaa taccaagaag acttgactta caagtttaag gtcttggaaa
    10141 aggatatcca gactagacta gctgtgataa aagaaatgca gggaactgaa gataagtaaa
    10201 aagagcccga cggctctttt ttaaaacgta aacaagttat agtgaattga atttagaata
    10261 gcacatcata gtttctaaag cattgttaga gattacttta aaatcctctt atcaatttgt
    10321 tcatattcta tttcaatcta ctatatatat cccatcaact atgcatcata atttaggtaa
    10381 ctcatactca ataaaaatca aaaagcaaac tagaaagcta ggcacagact gctcaaaaca
    10441 ccgttttaag gttgtggata gaactgacga agtcagtaac catacccatg acaagccgac
    10501 gctgacgtgg tttgaagaaa tttttgaaga gtatcattca ccatttcaca actaaatcga
    10561 agactttctg ccgtaatgaa aacacctgaa acagcttggt ttcggctatc cggaaacttt
    10621 aagacttagg ttcaaagttt aggtatggaa cttcgaagga ggtcgctacc gtccgtcatt
    10681 acttaggaaa gtcttaaaaa atctataaag taaaaagagc ccgacagctc tttttgttta
    10741 tactcaatga aaatcaaaaa gcaaactagg aaactagcca cgggctgctc aaaacactgt
    10801 tttgaggttg tagatacgac tgacgaagtc agtcacatat atacggcaag gcaacgctga
    10861 cgtggtttga agagattttc gaagagtatt attctccatc aaaggcatct ttaatatggt
    10921 caaagaagcc ttttttcttt ggatttactt tcaagtcacc agcagccgcg aattctttca
    10981 aggctacttt ttggcggtcg ttcaagcctg tcggtgttac gacattaaca gtaacgtatt
    11041 ggtcaccaac tgcaccgcca cgaaggctcg gtgccccctt actacgtagg cggaacttct
    11101 taccagtctg agttccctct ggaataacca attcaacatc accgtgaaca gttggaatat
    11161 ctactgtatc accaagagcc gcttggacaa agttgaggtt gagattgtag aagatagtcg
    11221 ttccttcacg ttcaaacttg tcgctagctt ccacagaaac tactacatac aagtcaccat
    11281 aaggtccacc gttaaagcct gcttcacctt gaccagcgag gcgaatttgt tgacctgttt
    11341 ccacaccagc agggattttc acatgtacgc tatgagcttg tttctcatga cctgttccat
    11401 gacaggttgt acatggatat ttgatttctt ttcctcgacc gtgacagaca tcacaggtta
    11461 cttggcgacg catcatacca agaggagtct gcgtatcgac gttaatgaca ccagcgccat
    11521 gacagcgtcc acaagtgact ggacttgtcc ctggcttagc accagatcca ttacatgtac
    11581 gacagccagc ttcacgatga tacttaactt ccttctcagt tccgaagata gcttcttcaa
    11641 aggtcaaatt gacacgatac tggagatcat ctccttggcg aggagcgttt ggattgcgcg
    11701 aagaaccgcc tccgccgaag aaacttgaga aaatatcctc aaaaccaccg aagccacctg
    11761 ccccattgaa accgccgaaa ccaccagctc caccaaaacc accattggcg cctgcagcac
    11821 catactggtc ataggcagca cgtttttggt cgtcactcaa agtctcatag gcttcttgaa
    11881 cttccttgta cttgtcctca gcaccaggct ccttgttgat atctgggtga tattttttgg
    11941 aaagcttacg ataagccttt ttgatttcgt ctgccgaagc gtttttggat acccccagac
    12001 gatcataaaa ttcagtattg ttcataattc aagatacaaa gggcgtcaaa cggacacagc
    12061 catctaggag ttttgacgac ggacgcttac gtcctagaaa aaactatctt tttggcacag
    12121 tccatagccc gtgttcagtt acgaacaccc ttattccttt ctattgatgt tctgaatcga
    12181 accaccattt aggtcgggtt caattccttt cttttatatt tagtaagaaa ttctgaaacc
    12241 cgtgttcagt tacgaacact ctttgttcct ttctattgat gagacaaaac ccaaacaaat
    12301 gagattccgt ccctttttat cgaaaaacag aggctgggtt gcaacctctg caaataagta
    12361 aattaacttt attttgattt taaatatcct ataagtacag aaatatttat atatttttgt
    12421 ctcttcttag tatttgccta tataattcca attgatcata agaaatacaa ctactgtcca
    12481 aatcatacca attatgaacg gtattacaaa tttatatgtt tgtatttcta atgatatcat
    12541 agctgatacc atcgctgata caaatgcaga caacaatact gaagtaacaa aattccttac
    12601 cgcttcatca tttttgacac aactatcatg ctcagctaat ataatttctc tatatatagt
    12661 caaacattct actggaatat tatctataaa accttttgct gcttcatagt tgccagcttg
    12721 attacaaaaa tcattataaa cttttcgtgt attttttaga tactcatcat ccaatacact
    12781 catcttattt ttccgtaaac tctccgtcta cgacgtcatc gcctgcgttt cctgttgctt
    12841 gtgcgccttc tgctccttct tgagcttgtt gcgctgctgc ggcttgttcg tagagtttca
    12901 cagcaaggcc ttgagctttt tcgttcaacg cttcaagttt cgctttcatg tcgtccaagt
    12961 tgttgtcttc ttgagctttc ttaaggtcat caagggcagc ttggacggcg tcacgttctg
    13021 cgtcgaagcc tttaccttca gtttccttga ttgtcttttc agtcgcaaag attgcttggt
    13081 ctacttcatt acgaaggtct acttcttctt tacgtttctt atcggcttca gcgtttgctt
    13141 ctgcatcttt catcatgcgg tcgatttctt cgtcagtcaa acctgagttc gattggatga
    13201 caatagtttg ttctttttga gttccaaggt ctttggcctt aacagacacg ataccgttct
    13261 tgtcgatgtc aaatgttact tcgatttgag gaattccacg aggtgcagct gggatatcag
    13321 tcaattggaa gcgtccaaga gtcttgttat ctgctgccat tgggcgttca ccttgaagaa
    13381 cgtggatatc aacggctggt tggttgtctg ctgctgttga gaagacttgt gatttagatg
    13441 ttgggattgt agtgttgcga tcgataagtt ttgtaaatac tccacccatt gtttcgatac
    13501 caagtgacaa tggcgttaca tcaagaagga caacgtcctt gacatcacca gtaatcacac
    13561 caccttggat agccgcaccc atagcaacta cttcatcagg gtttactgat ttgtttggtt
    13621 ctttaccagt ttcagcttta acagcttcaa caacggcagg gatacgagtt gaaccaccaa
    13681 caaggataac ttcgtcgatt tctgacaagc tcaaacctgc atctgaaagg gcttgacgaa
    13741 ctggaacttt tgtacgttca acaaggtcac gagtcaaatc gtcaaatttc gcacgagtca
    13801 aagtcatttc caagtgaaga ggtccagcct cacctgcagt gataaatggc aagctgattt
    13861 gtgttgaagt tacaccagaa aggtctttct tcgctttttc agccgcatct ttcaaacgtt
    13921 gcattgccat cttgtcagta gacaagtcga taccgttttc tttcttgaat tctgctacca
    13981 agtggtcaat gattttttgg tcaaagtcgt caccaccaag tttgttgtcc cctgcagttg
    14041 acaatacgtc gaagacaccg tcacccaatt caaggataga gacgtcgaat gtaccaccac
    14101 caaggtcaaa taccaagatt ttttcttctt tgtcagtctt gtccaaacca taagcaagag
    14161 ctgctgcagt tggttcgtta acaatacgtt ctacttcaag accagcaatt ttaccagcgt
    14221 cttttgttgc ttgacgttga gcgtcgttga agtaagccgg aactgtgata acagctttgg
    14281 ttactttctc accaaggtag tcttcagcgt agcctttcaa gtattgaagg atcatagctg
    14341 agatttcttg tggagtgtat tcttttccat ttgcagaaac tttttcagaa gttcccatct
    14401 tagatttgat agagataact gtatctgggt ttgtgactgc ttgacgtttt gcagcatcac
    14461 caacgatgat ttctccgttt ttgaatgaga ctacagatgg agttgtgcgg tttccttctg
    14521 ggtttgcgat gattttgctt tcagttcctt caagaactgc aactgctgag tttgttgtac
    14581 ctaagtcaat accgataatt ttagacatgt gtttttctcc ttgttagtta attttctatt
    14641 tttctttttg atactcttct taagtggcga cgccgtcaga gcttgacttc gtcaatctct
    14701 ttgactaaac tttgagccta aggtctcaaa atttgcgcaa atagcgccac ggcgaagagt
    14761 atcgtgtttg gttcgcttcg ctcactatta caaagccaaa catattttat ctttctttat
    14821 agtttattgt cgtttcggac aagttttcta ttctgtaaat tgcgacacga ggagtcgaaa
    14881 tcgattttat ttcgacgacg agttagtaag gaagctaggc aaacgccata tcgattgccg
    14941 ttttctgacg agttgcttta gctaccgtca gaattgccga atcgaacacg ccctaagctc
    15001 tgagtaaaaa agatagattt tcttgtgttc atcgaacact tcgtcaatct cctattttta
    15061 ctgcgagctt tttacgggct ttgtatctta gttatacacc actaccattg ctgggcgtag
    15121 gatgcggtca tggagtttgt agcctttttg aaagacttga gcgatggcat ctactgggtg
    15181 ttcatcgtct gctgggagag tttggatggc catatggtag ttatggtcaa attcgccatc
    15241 tgctgcgatt tcttcaattc cttcttcttt caaagcgtga atcaagcttt cttgcaccat
    15301 ccccaagccc ttcttcacat catctgtcaa accttcaact gcaagtgcac gctcaaggtt
    15361 gtcaagagat ggtaagattg cttttgccaa gtcctggcta cgataacgtt gcaagttttg
    15421 acgttcttca ttggcacggc gttggatatt ttgcatttct gcatgagcgc gaagatattt
    15481 gttttcgaac tcatctgcac gttcatttgc caagtccaac ttagactttt caggagttgt
    15541 ttcttcagct gtttccacaa cttcctcttc ttgaacttct tctacttctt cattttttat
    15601 atcttgggcc atgttcgcct cctttaatga tttcaatctt aatgtacttc gtaatgatta
    15661 ctgctgaggt agcggtaaaa atctgtcaac ttcatagtca aaacacggtt gaccacattg
    15721 acttgattga ttagctgttg gtaatccaga ttaactggac cgataatggc tagaattcca
    15781 actcctcgat aaggaatgag gaacttacta ctaatcaccg ctaggtcagc taaacaggac
    15841 tcttgaccgt ctgcaacacg aacattttgc atctgatcct cacgcaaccc ctcacgaatc
    15901 tccaaggcca ccttttgcgg ttggtcaaag aactgatagg cttctagatt ggcaaaattc
    15961 aagagattga ccttgcccgc catcacaatg ttttcgttga acatttcctt aaagatgtgt
    16021 tcaaagagat cgatgacatt atccgttgtt gtaaagtaac gctggataat ctgcggaatc
    16081 tccgtccgaa tcttgtagtg aatatctaaa acggtgtgac cgaggaaacg ttcctgaatg
    16141 atgctcttca gtttcagcaa atcctcctgc aagaagttcc ttggaatcag aaactgacta
    16201 gtaaccgttc gcgactcgtc tagggtaaat accgccaagg ctgtatgttg ccccaaaaca
    16261 acgatatcaa aggctgtcaa acgttgcctg ctcggctcaa catccagtgc cactaccgta
    16321 cagccactca ggtctgttag caagttagca gcctcttgca gaatatcctc caatttgaag
    16381 aattcctgat caaaggcttt gacaatctca tatacctcat tttcagccag ccggtgaaaa
    16441 tccagtgagt gtttcacata gtactgaaaa ccagcaacac ttggcatccg accgcttgaa
    16501 gtatgagcct tctcaagcaa cccttgtttt tctagttccg ccatgtcatt acgaatggtt
    16561 gcactgctag agttaataga ctcttgcaag gcttttgatc cgacaggttc gtgcgttttg
    16621 gtaaagatgt caataatcag atttaaaata tcctgctgac gctctgtaac catctcatca
    16681 ctcctctctg tctgatcaat tagcactcaa tgcatccaag tgctaactta tgattctatt
    16741 atacaccctt aaaagagaat gtcaagacaa aaactcaaaa aattagcact cttttatcaa
    16801 gagtgctaaa aatcaatctg aagacctaga accttgctat tcatctactc ggtatttcct
    16861 ttttagtctg aaataaccat gaattagata agaaatcaga aaagcatata aaacaaaaat
    16921 aagaaagaaa gacatagaaa gatcctctct aaacaaactc gtacaaacaa caagaccacc
    16981 taagaaagta gttgtacagg aacgaagtct agatcgcata acttcccatt tgagcccctt
    17041 actcatatag acttgatcct ctggaagtaa atcagaagac gatttacgaa gaatcgaaca
    17101 agaacctgct cctatcaatt cccaacctct atctctaaaa tcttgcagtt catgcttata
    17161 ttttttaaga aatctagaat catagatacg gtagatgaca tcgtctggtt gacattggtc
    17221 aaaatagaac aaaccaaaac gactcgttct atacctccaa cctttcaaat gcatctcatg
    17281 taaatattct tcttacttgt ccaaatcaac aatggtgaaa atccgaaatt ctactctgct
    17341 attcattgtc ttaccccaaa attagaaaac atgcctggcg ttatttatta gataattctt
    17401 tccacttttg actcaatctc caaaaaatat aagaaatctg aatcgcaaaa actatcaata
    17461 aaacccaatc tattatgaaa atcaaaaaca ctttccaact gaaagaacta cctccagtga
    17521 caaactttga gaaaaacggt agtagagcta aaaagagaag taaaatagga agcatccgca
    17581 ttgttaaaat ccgtttggca taaaaaaatc tttatttaaa ctaaaatatt atagcaaaat
    17641 ttacgccagt ttttgaacgg ctgatgtaga tattttatac tttcaaaatg tttaaatgtg
    17701 attatttatt tttgaaaaat agctcaccag cccgactgaa agtgcttata gaatgataat
    17761 aagtcgcctg ccgaaaacag cggaaaatag cggtgttatg cggagataat ctgacgcgat
    17821 gcgaaagtat attgcatact tattttcaac aatttagcag agtattttta taagtgtgat
    17881 ataatagaag tataatttgt tctgatagtt tattttatgg agaagtagat ttttagaatg
    17941 cggagggttc aatatggttg agtttataaa gtctaagaaa gaaatgagtg aggaggatat
    18001 taaagcaaat ttcatcactc ctgctattgt atccaaagga tggaaaaatg gtgagcatat
    18061 cgcttacgaa gaatacttca ctgatggtcg aattgaggtt agaggagata aggctcgtcg
    18121 taaagaagga aaaaaatcag actattcact gtattaccaa tttggaactc gaattgcaat
    18181 tgttgaggca aaggataata aacacagcgt tcgagcagga ttacaacaag ctattgaata
    18241 tggagagatt ttagatgttc catttgttta ttcttcgaat ggtgatggct ttattgaaca
    18301 cgaccgtatc acgagagaag aacgtgagct ggagttagac gaattcccta ctcgtgaaga
    18361 attattttct cgtatgacga aggaaaaagg attgatgtac gaaattacag aagctatctc
    18421 aactccatac tatacagacg ccttctcaat gaaaacgcca cgctattatc agcaaatagc
    18481 tatcaaccgt actattgaaa cagttgccag aggacaaaaa cgagtaatgt ttgtgatggc
    18541 aacaggaacg gggaaaacgt tcatggcttt tcaaattatt catcgccttc gaaaagctgg
    18601 tttggctaaa cgagttttat tcttagcaga tagaaacatc ttagtggacc aaacgatggc
    18661 tgaagacttt aggccattcg aaaaggtaat gacgaaaatt acaccaaaac ttttgactgc
    18721 tcctgaaaaa ttaaattctt ttgaaattta tctagggctt tatcagcaac taactggtga
    18781 agatggaact gaaacacatt atcaaaaatt tgacaaagac ttctttgatt taatcgtaat
    18841 tgatgaagcg caccgtggtt cagctaagga agacagtaac tggcgtaagg tgattgatta
    18901 tttcagttct gcgacacaga ttgggatgac cgctactcct aaagaaacca agaatgcttc
    18961 caatacggaa tactttggtg agccaatcta tacttatagt ttaaaacagg gaatcgagga
    19021 tggttttttg gctccatatc gtgttatgag ggttaattta gatgtggatg tggatggtta
    19081 tcgtccagaa actggaaaag ttgatgctaa cggacaatta atagaagata ggtactacgg
    19141 caggaaagat tttgataaaa ccattgtcat tgatgataga acgcaaagag ttgccaagtt
    19201 tgtttctgat tatatgaagc aaaacaatgc acgatttgat aaaacaattg ttttttgtgt
    19261 tgatattgac catgccgagc gaatgcgtgc tgcacttgta aaagagaatc tagacttagt
    19321 ccaagaagac tatcgttatg tcatgcaagt aactggtgac aacgctgaag gaaaagctca
    19381 actggataac tttatggatg tcaattctaa ttttcccgct attgtaacaa cgtctaaatt
    19441 attaacgaca ggagttaatg ctaaaacatg tcgtttgatt gttttagact ctaatatcca
    19501 atccatgact gaatttaaac aaattattgg tcgtggcaca cgtctttatc ctcaaaaggg
    19561 gaaagaattt tttacgatta ttgattttcg aaatgttacc aatttgtttg ctgaccctga
    19621 ttttgatggt gaaccagtga aggtgctgga aacaggtgcg aaaacagtca gtggttctac
    19681 gcccggtttc gtagataagg aaggtgaccc agtagaaaaa tatatcgtta cagacaagca
    19741 ggttaccatt cttaattcta ctgttcaagt attggatgaa aacgggaaac tgattaccga
    19801 aagcctgacc gactacactc ggaagaatat cttaggtagc tacgccactt tgaacgattt
    19861 tatcacagtt tggcatacgg cggataaaaa gaagcttatc ttagacgaac tttataaaaa
    19921 aggagtttat ctagatgcta ttcgagagtc ggagggaata tcagaacaag aaatcgatga
    19981 ttttgattta ctcctaaaac ttgcctatgg tcaaaaagaa ttaaccaaaa cggaacgtat
    20041 caataaactc aaacaaagcg gatatttata taaatatagt gaggaagcgc gtgctgtttt
    20101 ggaaatttta ctgaacaaat acatggataa aggtattgga gaactcgaaa gcattgaaac
    20161 attaaaactt ccagaatttc agatatatgg tggaaccttc aaaatcatca atacttattt
    20221 tggagataaa aaacgatatt tacaagcaat taaagaattg gagcaagagc tatttacagt
    20281 agcttaatga aaggaaagta tgtcaattac atcatttgta aaaagaattc aagatatcac
    20341 tcgaaacgat gctggtgtta atggtgatgc tcaacgtatt gagcaaatgt cttggttatt
    20401 attcttaaaa atttatgata gccgtgaaat ggtttgggaa ttagaagaag acgagtatga
    20461 gtcaattatc ccagaggaat taaaatggcg aaattgggct catgctcaaa atggggaacg
    20521 ggtattgaca ggcgatgaat tacttgattt tgtcaataac aagttattca aagagttgaa
    20581 agagcttgaa ataacttcaa atatgcctat tcgaaaaacg attgttaaat cagcttttga
    20641 agatgcgaac aactatatga aaaatggcgt cttgttacgc caagtcatca atgttattga
    20701 tgaagttgat ttcaatagcc ctgaagatcg tcattcgttt aatgatattt acgaaaaaat
    20761 tcttaaagat attcaaaatg ctgggaactc aggagaattt tatacgccac gtgcagcgac
    20821 tgattttatt gccgaagttc ttgacccaaa acttggagaa tcaatggcag accttgcttg
    20881 cggaacagga ggcttcttga cttcgactct gaaccgttta agtagtcaac gtaaaactag
    20941 tgaagatacc aaaaaatata atacagctgt ttttggtatt gaaaagaaag catttcctca
    21001 tcttttagca gttacaaatc tgtttcttca cgaaattgat gaccctaaaa ttgttcatgg
    21061 aaatactttg gagaaaaatg ttcgtgaata tacgaatgat gaaaaatttg acattattat
    21121 gatgaatcca ccttttggag ggtcagaatt agaaacaata aaaaataact ttccagcaga
    21181 attacggagt tctgaaacag ctgatttatt tatggctgtc attatgtatc gtttgaaaga
    21241 aaatggtcgt gttggagtta ttttacctga tggttttcta tttggtgaag gtgtaaaaac
    21301 tcgcttgaaa caaaaactgg tagatgagtt caacttgcat acgattatta ggttgcctca
    21361 tagtgtcttt gcaccgtata caggaatcca tacgaacatt cttttctttg ataaaacaaa
    21421 gaaaacagaa gaaacttggt tttatcgttt agatatgcca gatggttata aaaatttctc
    21481 gaaaactaag ccgatgaagt cagaacactt caatcctgtt cgtgactggt gggaaaatcg
    21541 tgaagagatt ctggaaggta agttctacaa atctaaatca tttacaccta gtgaattggc
    21601 tgagttgaat tataatttag accagtgtgg ttttccaaaa gaggaagagg aaatcttaaa
    21661 tccctttgag ttgattcaga attatcaagc ggaaagagca actttaaatc ataagattga
    21721 taatgtatta gctgatattt tgcagttgtt ggaggacaaa taatgacacc agaacaactt
    21781 aaagcaagta ttctccaaag agcgatggaa gggaaattag tgccgcaaaa tcccaatgac
    21841 gaacctgcaa gtgaattatt aaagagaatt aaagctgaaa aagaaaaact tatcagtgaa
    21901 ggaaaaatca aacgagataa aaaggaaact gagatatttc gtggtgatga tgggaaacat
    21961 tatgggaagt ttgctgatgg aag
//
LOCUS       DAVLTT010000029        21714 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLTT010000029 DAVLTT010000000
VERSION     DAVLTT010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21714
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.029"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            27..1712
                     /locus_tag="VYN15_001235"
     CDS             27..1712
                     /locus_tag="VYN15_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HEV1452554.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKD
                     KGLWYYLNESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
     gene            complement(2192..2341)
                     /gene="rpmG"
                     /locus_tag="VYN15_001236"
     CDS             complement(2192..2341)
                     /gene="rpmG"
                     /locus_tag="VYN15_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1452555.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(2357..2539)
                     /gene="rpmF"
                     /locus_tag="VYN15_001237"
     CDS             complement(2357..2539)
                     /gene="rpmF"
                     /locus_tag="VYN15_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV1452556.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            complement(2691..2891)
                     /locus_tag="VYN15_001238"
     CDS             complement(2691..2891)
                     /locus_tag="VYN15_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1452557.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(2894..3901)
                     /locus_tag="VYN15_001239"
     CDS             complement(2894..3901)
                     /locus_tag="VYN15_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1452558.1"
                     /translation="MTEKLINSKPNGVFALILIELTLVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            4093..6123
                     /locus_tag="VYN15_001240"
     CDS             4093..6123
                     /locus_tag="VYN15_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1452559.1"
                     /translation="MFDYRALVILMTLMDHCEVSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            6127..6411
                     /locus_tag="VYN15_001241"
     CDS             6127..6411
                     /locus_tag="VYN15_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1452560.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            6424..7770
                     /locus_tag="VYN15_001242"
     CDS             6424..7770
                     /locus_tag="VYN15_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1452561.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            7774..8631
                     /locus_tag="VYN15_001243"
     CDS             7774..8631
                     /locus_tag="VYN15_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1452562.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDENKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            8628..9560
                     /locus_tag="VYN15_001244"
     CDS             8628..9560
                     /locus_tag="VYN15_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV1452563.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            9793..11496
                     /gene="ilvD"
                     /locus_tag="VYN15_001245"
     CDS             9793..11496
                     /gene="ilvD"
                     /locus_tag="VYN15_001245"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV1452564.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(11657..11737)
                     /locus_tag="VYN15_001246"
                     /pseudo
     CDS             complement(11657..11737)
                     /locus_tag="VYN15_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(11795..12136)
                     /locus_tag="VYN15_001247"
     CDS             complement(11795..12136)
                     /locus_tag="VYN15_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1452565.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            12260..13111
                     /gene="rgg"
                     /locus_tag="VYN15_001248"
     CDS             12260..13111
                     /gene="rgg"
                     /locus_tag="VYN15_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV1452566.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYKLNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            13301..14548
                     /locus_tag="VYN15_001249"
     CDS             13301..14548
                     /locus_tag="VYN15_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV1452567.1"
                     /translation="MKLLFRNQAYRLLTLSRFFNAFGASIFNLVFIVYASTLPQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDRFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFFGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGFSLLAIFLTILNLKNDI"
     gene            14626..15915
                     /locus_tag="VYN15_001250"
     CDS             14626..15915
                     /locus_tag="VYN15_001250"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV1452568.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            15906..15986
                     /locus_tag="VYN15_001251"
                     /pseudo
     CDS             15906..15986
                     /locus_tag="VYN15_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            16253..16567
                     /locus_tag="VYN15_001252"
     CDS             16253..16567
                     /locus_tag="VYN15_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452569.1"
                     /translation="MWVLVFILFIIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKKPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            16577..16783
                     /locus_tag="VYN15_001253"
     CDS             16577..16783
                     /locus_tag="VYN15_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1452570.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            16783..16980
                     /locus_tag="VYN15_001254"
     CDS             16783..16980
                     /locus_tag="VYN15_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452571.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            16983..17717
                     /locus_tag="VYN15_001255"
     CDS             16983..17717
                     /locus_tag="VYN15_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV1452572.1"
                     /translation="MKKKRRLLFLMSIVFWGVLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            17729..18370
                     /locus_tag="VYN15_001256"
     CDS             17729..18370
                     /locus_tag="VYN15_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1452573.1"
                     /translation="MKLLKNLGWILLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYVSRKGLVYSISLHALNNLVGFLMILML"
     gene            18388..18618
                     /locus_tag="VYN15_001257"
     CDS             18388..18618
                     /locus_tag="VYN15_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452574.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            18654..18734
                     /locus_tag="VYN15_001258"
                     /pseudo
     CDS             18654..18734
                     /locus_tag="VYN15_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            18970..20733
                     /gene="aspS"
                     /locus_tag="VYN15_001259"
     CDS             18970..20733
                     /gene="aspS"
                     /locus_tag="VYN15_001259"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV1452575.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALVLEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            20711..21652
                     /locus_tag="VYN15_001260"
     CDS             20711..21652
                     /locus_tag="VYN15_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1452576.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
BASE COUNT         6473 a         3745 c         4594 g         6902 t
ORIGIN      
        1 gaaaataaat atgtaaggaa atttaaatga aaaaaactac aatattatca ttaactacag
       61 ctgcggttat tttagcagca tatgtcccta atgaaccaat cctagcagat actcctagtt
      121 cggaagtaat caaagagact aaagttggaa gtattattca acaaaataat atcaaatata
      181 aggttctaac tgtagaaggt aacataggaa ctgttcaagt gggtaatgga gttactcctg
      241 tagagtttga agctggtcaa gatggaaaac cattcacgat tcctacaaaa atcacagtag
      301 gtgataaagt atttaccgtt actgaagtag ctagtcaagc ttttagttat tatccagatg
      361 aaacaggtag aattgtctac tatcctagct ctattactat cccatcaagc ataaaaaaaa
      421 tacaaaaaaa aggcttccat ggaagtaaag ctaaaactat tatttttgac aaaggcagtc
      481 agctggagaa aattgaagat agagcttttg atttttctga attagaagag attgaattgc
      541 ctgcatctct agaatatatt ggaacaagtg cattttcttt tagtcaaaaa ttgaaaaagc
      601 taaccttttc ctcaagttca aaattagaat taatatcaca tgaggctttt gctaatttat
      661 caaatttaga gaaactaaca ttaccaaaat cggttaaaac attaggaagt aatctattta
      721 gactcactac tagcttaaaa catgttgatg ttgaagaagg aaatgaatcg tttgcctcag
      781 ttgatggtgt tttgttttca aaagataaaa ctcaattaat ttattatcca agtcaaaaaa
      841 atgacgaaag ttataaaacg cctaaggaga caaaagaact tgcatcatat tcgtttaata
      901 aaaattctta cttgaaaaaa ctcgaattga atgaaggttt agaaaaaatc ggtacttttg
      961 catttgcgga tgcgattaaa cttgaagaaa ttagcttacc aaatagttta gaaactattg
     1021 aacgtttagc cttttacggt aatttagaat taaaagaact tatattacca gataatgtta
     1081 aaaattttgg taaacacgtt atgaacggtt taccaaaatt aaaaagttta acaattggta
     1141 ataatatcaa ctcattgccg tccttcttcc taagtggcgt cttagattca ttaaaggaaa
     1201 ttcatattaa gaataaaagt acagagtttt ctgtgaaaaa agatacattt gcaattcctg
     1261 aaactgttaa gttctatgta acatcagaac atataaaaga tgttcttaaa tcaaatttat
     1321 ctactagtaa tgatatcatt gttgaaaaag tagataatat aaaacaagaa actgatgtag
     1381 ctaaacctaa aaagaattct aatcagggag tagttggttg ggttaaagac aaaggtttat
     1441 ggtattactt aaatgaatca ggttcaatgg ctactggttg ggttaaagac aaaggcttat
     1501 ggtattactt aaacgaatca ggttcaatgg ctactggttg ggttaaagac aaaggcttat
     1561 ggtattactt aaatgaatca ggttcaatgg ctactggttg gtttacagtt tctggtaaat
     1621 ggtactatac ctataattca ggagatttat tagtaaacac gactacaccc gatggctatc
     1681 gagtcaatgc taacggtgag tgggtaggat aggtatccat tagctaaatc taatcattct
     1741 gaactaaaaa atcttcttac atatgtagga agattttttg gattctcaaa actagtttaa
     1801 aagactacgc tatttaaacc aattttaaga atggatatat aaggatattc agaaatctag
     1861 ttggtcaact tttgtatttt gaatatacct tagatggtga cgatgtcttg gtatatctgg
     1921 tactcactta catattctaa cttattttaa ctaagatgca actgtagttg gtgaatttgc
     1981 tacaaatagt gtagaggcgt tatttgaaaa atatacaaaa aaggaacccc aacttacatt
     2041 tgagtttctc ttacttttaa tcgtccgaat ccgtattctt atttcaaaaa atgtagtcat
     2101 tcgaatgatt tctcttgcaa tatagtgaaa ttaacaaaaa gaaaaaacgc tgatcaagcg
     2161 tttttcttct gtattgattc gtattgaatg cttacttcac ttctgtaaac acaacgtgtt
     2221 tgcgaagttt tggtgagtat ttcttcaatt gaaggcggtc tggagtgtta cgtttgtttt
     2281 tagaagtaag gtacaagcgt tcaccagatt ctttgtgttc aagtgtaata tttacgcgca
     2341 tggtatctcc cttctattat tcagctgatg cagctttagc gattttacgt cctttgtagt
     2401 atcctttaag tgatacacgg tgagaacgtg agtaatctcc agtagtttcg tcaaagttta
     2461 cagatggagc tgttactttg tagtgtgtac gacgtttgtt tttcttcgct tttgaagtgc
     2521 gacgtgcagg tactgccatt ttgatttctc ctttaggtat ttatattcga ttcaatctac
     2581 tgattttcat caaccatact aggataacac attttttttg taaagtaaag ttacttgaca
     2641 aaaaaagatg aaaaaattct cctatccgac acggcagaca ggagaaggtg ttaaatatca
     2701 atctcaaatg gttcgtcaat ggtttctgat acgtattttc cgtctttttt ccgttgcttg
     2761 acacactctg tgaggagata ttcgatttgc ccattgactg aacgaaagtc gtcttctgcc
     2821 catgatgcga gtgcagcgta taactttgtt gagagtcgaa gggggatctg ctttttttta
     2881 gcttcagcca tctttagtaa agacttcctg tgttgacaat tggttgtgca tcatgattgc
     2941 cacaaagaac gacaaggaga tttgaaacca tggcagcttt tcgttcttcg tcaagttcta
     3001 ccaattcccc ttcattgagc cgttctagtg ccatttcaac cattcctaca gcaccatcta
     3061 caatcatctt ccgtgcatca ataatggcag atgcttgttg gcgttgaagc ataacggcag
     3121 caatttctgg agcataagct aggtaagtga tacgtgcttc aaggatttcc aagccagcat
     3181 cctcaacacg actttggatt tcttcacgaa tacggttagc tacaatttca ctagagccac
     3241 ggagactacc ttcatctgct tgcccgtcac ccgtagtatc cacattagga gacacatcgt
     3301 aaggatagat gcggacaata ttacggaggg cgctatcaca ttgcaatgaa agatattctt
     3361 tgtagttatc aacgttgaag actgccttag cggtatcgac aactctccaa gttaccgcga
     3421 taccgatttc tacagggttt cctaagcaat cattgatttt ttgacgggaa ttgctcaagg
     3481 tcatgacttt gagggaaatg tgtttcttgc caatttcaag atttacatca ttgtcatttg
     3541 atgatttagc acctaaaaaa ggagattttg tgctaacatc accactttgt ccaagtcgag
     3601 tgtggtttgc agggttgact gctacgctga agggattgac aaagtaaaaa ccaggttctt
     3661 tgatggtacc tgtataatta ccaaagagtg tcagaaccag agcttcctga ggtttgacaa
     3721 cttttaaacc agcatgagct agacctgcaa ttacgattag taaaggtccg ataataattc
     3781 caaaaatgtt ttccgaacca acacccatta taaatataaa gataccaagt acgagcgtca
     3841 attcaatgag aatcaatgcg aatacaccat ttggttttga attgattagt ttttcagtca
     3901 taagaatgac ctcccattat ttgatatcta aatgatatca ctttgttttt aaaagtcaat
     3961 agaaagttga aaaataatca ctaaaaactt tcagcccaat aatttctttt aaaaggtgag
     4021 attatattgt gctcaaatac tcttttattc ttataacttt tacactataa ttgtagttag
     4081 aaaggaagag aaatgtttga ttatagagca ctagttattt tgatgacttt gatggatcat
     4141 tgtgaggtat cattatatga gttatctgtt aaggtgagct tacctataaa ggaagtcaaa
     4201 gaaggaatag attatttagt gccttatcta gctaataaag ggatagtgct ggataaaaag
     4261 caaggtcgct atagtttatc aaatcgtacg aagcagtctt tgacagatat tattaagtcg
     4321 gatgaattgg ttttaccaaa gtcgactcgc ttagctttaa tctatcttta cactttttgc
     4381 cgattagatt ttatatcgaa tagtcattac caagactttt tgaaagtaag taagaataca
     4441 accttatctg atattcaatc attaagaaag attatgttag ataatgattt ggagctaggg
     4501 tacagtagag caaaaggtta tactttacac ggttcagagt ggaataagca ccgcttagct
     4561 tttcaaatgg ttagtgagtt gctggaatcc tccataggga tttggggttt ggattatgtt
     4621 ttatccagtt gggggtattc attaacttat gatttgattg atcaggtagt taaagattat
     4681 tatgagaagc tacagctagt acctattgtt aatcaattaa aagtttacct tttcggttta
     4741 gtattcattc tgtgtaggta tcaaagggat gttgaaagag tatgtctttc agagacatta
     4801 gtatctcctg ttattcaaga tataaccact attttattgg atacagtggt tgatttggga
     4861 attatagata cggtgttttc tgaggatgat tatcgctata tcaccgtttt attatcaagt
     4921 tgctttgaag gtgaagtaga tgttgctccg gtttacttta atcaattaac agaggctatt
     4981 ataagtagaa tggaagatat ttctttgtta cattttaaac aaagggaagg attgagagaa
     5041 aatcttcgcc gccaccttat accggcttac tatagattaa agttcggcct acctagttca
     5101 aatgaatatg tattgcatgt taaagaacat tatcctgatt tatttgaatt agtcaaagat
     5161 tctttgatgc ccttgatgga cgctattgac aatcccatac ctgatagtga aacagcatat
     5221 tttgttatcc atttcggagg ttatttaaag aaagcagata ctttgcctca aaaatggtat
     5281 aaagcagcaa tcatttgtcc taatggtgtt agttcttcat tgatgttaaa agagaatcta
     5341 ttagcattat ttcctcaaat tgagtttata ggaacctcaa agattgatga tttacaggtg
     5401 aaagctagta gtgactatga tatggttttt tctaccataa aggtggagac agaaaagcca
     5461 aattatctag tttcggttat gatgactgaa gagcaagcaa tacaactagt agaactagtg
     5521 ttaaaagatt ttccgaattt agagtatgga gattttgaga ttgaacaaat cctgaatatt
     5581 gtcaaaagat atggaattat tacacaagaa ttggaattaa gattggcgtt aaagaattat
     5641 ctttaccaaa aaaatgatag aaaggaaatt gtaccagtgc tagaacaact tattaccaaa
     5701 gaaacctatc aggttagttc gcaaaaatta ggatggaagg aggcgattcg tttagcagct
     5761 aaaccgcttt tggatcaaga taagataact gagaactacc ctgaggcaat gattcaaaaa
     5821 gtagaagagt ttggaccttt tattaattta gggaagggag tagcaattcc tcacgctcgg
     5881 ccagatgaag gtgtgaatga aataggaatg tcaatgttag ttttggaaga accgatttat
     5941 ttattggata atccagaaca agaggtaaga ttgttgattt gtattgcagc cattgataat
     6001 gagagtcatt taaaggcttt gtcacattta acaacaattt taagagataa aaatcatgtt
     6061 caaactttaa tatcatcaaa aaactataat gatattaaaa tgataattaa acaggaggat
     6121 tagataatgt taaaaattgg tacagcttgt ggttcaggat taggttcaag ttttatggta
     6181 cagatgaata ttgaatctgt attgagtgat ttgaatgttt cggatgtaga agttgaacat
     6241 tatgatttag gtggagcaga tccaaatgca gctgatattt ggattgttgg tcgtgatcta
     6301 gctgattcag ctagtcatct tggagatgtt cgtatcttaa atagtattat tgatatggat
     6361 gaactacgag aattaattac taaactttgt gaagaaaaag gacttatata ggaggctagc
     6421 gtcatgatga agttcatatt ggatattgtt agtacaccag ctattttagt agctttaatt
     6481 gcaattttag gattagttct tcagaagaag aaattacctg atattattaa aggtggaatt
     6541 aagacctttg ttggtttctt agttgtatct ggtggtgcag gaattgtaca aaattcttta
     6601 aatccatttg gtaccatgtt tgagcatgct tttcatttat ctggcgttgt gccgaataat
     6661 gaagcaattg tagctgtagc tttaacaaca tatggctcag ctactgcaat gattatgttt
     6721 gcaggaatgg tgttcaatat cttaatcgct cgttttactc gatttaaata tattttttta
     6781 acagggcacc acactctata tatggcatgt atgattgcgg tcattttatc agttgctggc
     6841 tttactagct tgcctctcat cttactagga ggattagcac tcggtattat tatgagtatt
     6901 tccccagcat ttgtgcaaaa atatatggtt caattaactg gaaatgacaa ggtggcttta
     6961 ggtcatttca gttctttggg atattggttg agtggtttta ctggtagcct tatcggtgac
     7021 aaatcaaaat caacagagga cattaaattt ccaaagagtt tagctttttt acgtgatagt
     7081 actgttagta tcactttatc tatggcagtt atttacatta ttgtagctat ctttgcaggg
     7141 tcagaatata tagaaaaaga aatcagtagt ggtacaagtg gtctagttta tgctttacaa
     7201 ttagcaggtc aatttgcagc aggggtattt gttattttag caggtgttcg ccttattttg
     7261 ggcgaaattg ttccagcctt taaaggtatt tcagagcgtc ttgtacctaa ttcaaaacct
     7321 gctttggatt gtccgattgt ttatacttat gcacctaatg cagttctaat tggatttatc
     7381 tctagtttta ttggtggttt agtaagtatg gcaattatga ttgcttcagg aacggttgtt
     7441 atcttaccag gcgttgtgcc tcatttcttc tgtggagcga ctgcaggtgt tattgggaat
     7501 gcatctggtg gtgttcgtgg agccactatt ggagcatttt tacaaggtat tttaatcagt
     7561 tttctcccag tctttttaat gccagttttg ggaggactcg gtttccaagg atcaactttc
     7621 tcagatgcag attttggtct atcaggaatt attttaggaa tgttaaatca atttggctca
     7681 caagcaggca ttgtgattgg tcttgttctt attttagcag ttatgtttgg agtatccttt
     7741 attaaaaagc catctgcaaa ggaggaataa gggatgattt taagtaaaaa tagagaagat
     7801 gagttaagaa aatttgcgac taacatccga ttaaatactc ttagaacatt gaatcatctt
     7861 ggattcggac attacggagg aagtctgtct atcgtagaag ttttagcagt gctttatggt
     7921 gaaataatgc caatgactcc agaaatattt gcagcacgag atagagatta tttcatatta
     7981 tcaaaaggtc atggaggacc agctctatac agtacactct atttgaatgg tttctttgac
     8041 aaagaattct tatattcttt aaatacaaat ggaaccaaat taccgtctca tcctgataga
     8101 aatctaacgc caggcataga tatgacaacg ggctctttag gacaaggaat tagtgttgca
     8161 actggacttg catatggtca gagaataaga aagagtccct tttatactta tgctattgtt
     8221 ggagatggtg agttaaatga aggacaatgt tgggaggcta tacagtttgc ttctcatcaa
     8281 cagttatcca acttaattgt atttgttgat gagaacaaaa aacaattaga tggttttaca
     8341 aaggatattt gtaatccagg tgatttcgta gaaaaatttt cagcatttgg atttgaatcc
     8401 attagggtca agggttcaga tattagagaa atttatgaag ggattgtcca attaaaacag
     8461 tcaaataatt catcacctaa gtgcattgta ttagatacta ttaaaggtca aggggttcaa
     8521 gagctggaag aaatgaaatc caatcatcat cttcgcccta ctgtagagga gaaacaaatg
     8581 ttaacttcag ttgtagaaag attaagtcag gaattggagg aaacagaatg atgagaagta
     8641 cgaaagaatt acggcatgta tatagagact tccttttaga ggctaatcaa agttattctg
     8701 atatagtagt cttagaagcc gatttgtcaa gttcgatggc tactcataat cttgaaaagg
     8761 acttcggaga ccgttatgtg aatgttggga ttatggaagc agaaatggtc ggccttgcag
     8821 caggcttgtc tattcagggg tttagacctt atcttcatac atttggtcct tttgcttcac
     8881 gaagagtatt tgatcaatta tttatttctc ttggatacgc acaattggat gccactgtga
     8941 ttggatcaga tgcaggagta acggcagaga tgaatggtgg aacacatatg ccatttgaag
     9001 aaattggatt gttacgttta attcctaaat caatcatttt cgaagcaact gatgatatcc
     9061 aatttcgtga aatattgaac cagacattag acttaaaagg actaaaatat attcgaacaa
     9121 ttagaaaagc tccagttcct gtgtatcaag gtggagaaga tttttctaaa ggctacattg
     9181 agttaaggca tggtgaagat cttgtaatcg ttgcttctgg cataatggtt gctccaagta
     9241 ttcgagttgc agatgaactg tctaaattag gttattcagt aggtgtgata gatttattta
     9301 gaatcaaacc gataccagaa cagataaaaa caatgttaag tggaaaaact atatttactg
     9361 tagaaaatca caatcagata ggtggaattg gcagtgcttt atgtgaatta ttctctgatg
     9421 atggaataac aaaaattcat cggatgggtg ttcaagaaag attcggtcaa gtagggaaaa
     9481 tggattatct tcttaatgag tatggtttga gtgaatcgaa tataaaagag aaggttctag
     9541 aaatttataa tgcaagatag atgttaaata cacttatctg aaagaatttc tgtaaaaatt
     9601 acagtacgtt atttaaagaa agcggattaa aaagcatatt ctggtcatca gaaagtgcac
     9661 taatccgctt tgttgttttt aattttaaat atttcacatg tgtatagaat tttctgaaaa
     9721 ttcaagaatt ttattctgtt cattgccttt aaattgtgct ataatagtaa aaactgaaat
     9781 gggagggata agatgactga attagataaa cgtcaccgca gtagcatcta tgacagcatg
     9841 gttaaatcac ctaaccgtgc tatgcttcgt gcgactggta tgacagataa ggactttgaa
     9901 acatcgattg tgggagtgat ttcgacttgg gcggaaaata caccatgtaa cattcacttg
     9961 catgatttcg ggaaactggc taaagaaggt gtcaaatctg caggcgcttg gcctgtacag
    10021 tttggaacca ttaccgtagc ggacgggatc gctatgggaa cgcctggtat gcgtttctct
    10081 ctaacatctc gtgacatcat cgcggactcc atcgaggcgg ctatgagtgg tcacaacgtg
    10141 gatgccttcg tcgctatcgg tggctgtgac aagaacatgc ctggatctat gattgctatt
    10201 gctaatatgg atatcccagc tattttcgcc tatggtggaa ctattgcacc gggaaatctt
    10261 gatggtaaag atatcgactt ggtttctgtc tttgaaggta tcggaaaatg gaaccacggt
    10321 gacatgacag ctgaggacgt gaaacgtctt gaatgtaatg cctgccctgg ccctggtggt
    10381 tgtggtggta tgtatactgc taataccatg gcaactgcta tcgaagttct agggatgagt
    10441 ttgccagggt catcctctca cccagctgaa tcagctgata agaaagaaga tatcgaagca
    10501 gcaggacgtg ctgttgttaa gatgttggaa cttggtctca aaccatcaga tatcttgact
    10561 cgtgaagcct ttgaagatgc tattactgta acgatggctc tcggtggttc tacaaacgcc
    10621 actcttcact tgctcgccat tgcccatgcc gcaaatgttg acttgtcact tgaggacttc
    10681 aatacgattc aagaacgtgt gcctcacttg gccgacttga aaccatctgg tcagtatgtc
    10741 ttccaagacc tctacgaagt cggtggtgtc cctgcggtta tgaagtactt gttggcaaat
    10801 ggtttccttc acggagatcg catcacatgt actggtaaga ctgtagctga aaacttggct
    10861 gactttgcag acttgactcc aggccaaaaa gttatcatgc cacttgaaaa tccaaaacgt
    10921 gcggatggtc cgcttatcat cttgaacggg aaccttgctc ctgacggtgc agttgccaag
    10981 gtatcaggtg ttaaagtgcg tcgtcacgtt gggccagcta aggtctttga ctcagaagaa
    11041 gatgcgattc aggccgttct gacagatgaa atcgttgatg gcgatgtagt cgttgttcgt
    11101 tttgttggac ctaaaggtgg tcctggtatg cctgagatgc tgtcactttc ttcaatgatt
    11161 gttggtaaag gtcagggaga taaggtggcc ctcttgacgg acggacgttt ctctggtggt
    11221 acttatggtc tggttgttgg acatatcgct cctgaagctc aggatggtgg accaattgcc
    11281 tatctccgta ccggcgatat cgttacggtt gaccaagata ccaaagaaat ttccatggcc
    11341 gtatccgaag aagaacttga aaaacgcaag gcagaaacaa ccttgccacc actttacagc
    11401 cgtggtgtcc tcggtaaata tgcccacatc gtatcatctg cttcacgcgg agccgtgaca
    11461 gacttctgga atatggacaa gtcaggtaaa aaataaactc atactcgaaa atctcttcaa
    11521 atcacgtcaa cgtcgccttg ccgtaggtat ggttactgac ttcgtcagtt ctatccacaa
    11581 cctcaaaaca gtgttttggg ctgacttcgt cagttctatc cacaacctca aaacagtgtt
    11641 ttgagctgac ttcgtcagtt ctatccataa cttcaaaaca gtgttttgag caacctgcgg
    11701 ctagttttct agtttgccct ttgattttca ttgagtatca aaaagcaagc cattttcggc
    11761 ttgctttttt catctttaaa agtgattggc ctgcttaacg aggtggtagt ccaagggcaa
    11821 tacggccata gcgactgatt cgtgtgattt tccaagcagg cgaccaggta acttcaacct
    11881 tgatatcttt gataccctcg atttgtttca gacctgccac gatttcaata ggcaggcttt
    11941 cggcgcaatc acaggcagta tcggtgaagg tcatgacaat cttgcagagc cccgtttcat
    12001 ccagattgat ttcataaatc agacctagat tgtaaacatc caattccaca tctgtatcaa
    12061 aaactttctc tagtttttcg ataatttggt cttgcaaggc caaagcacgg tcattgattt
    12121 tgatatcgtc tctcatagca gtccctccac gtgataaata tcctctattt tctcatgatt
    12181 ctgacaattt ggcaagtttt tgatgaattt tctgaaaaat atgataaaat gaagaaaata
    12241 cgggatcaag gggaagtcta tggagcagat tggaaaagtc tttagacaat tacgagaatc
    12301 aagaaatatc tcactgagac aagcaaccgg aggacaattt tcgccgtcta tgttgtcccg
    12361 ttttgaaaca ggtcagagtg agctttcggt ggaaaagttt ctatttgctc tggaaaatat
    12421 atctgccagt gtggaggaga tcctctttct ggcgagaggt ttccagtatg atacagattc
    12481 tgagttgaga aaagaaatta cagatgtctt ggaaccaaag aatatagcac ctcttgagga
    12541 cttatatcgc agggagtatc aaaagcatgc ccattctcac aacaaacaga aacatattct
    12601 aaatgccatt atgatcaagt cttatatgaa gagcatggat gaaagggtag agttaacagc
    12661 agaggaagga aaagtccttc atgattattt gttttctacc gagatctggg gaatctataa
    12721 actcaattta ttttcagtca gttctccatt tttatctgtt tctcttttta ctagatatgt
    12781 acgagaaatg gtacgtaaat ctgattttct aatggaaatg tctggcaatc gaaacctttt
    12841 tcatactata ctattgaatg gctttttagc tagtattgag tgtgaagaat ttaccaatgc
    12901 ctattatttt aaacgtgtta tcgaagagca tttctacaag gaaaatgaga cctatttccg
    12961 aattgtttat ctgtgggcag aaggtctcct tgatagcaag caaggtagag tcaaggaagg
    13021 ccagaaaaag atggaggatg ctgtccgtat ttttgagatg cttggctgta ataaatctgc
    13081 cgaatactat agaaatacga ccgaatgttg aatatctgca aactaagaaa aaatttgaag
    13141 cgatagaact gttgcccttt ctcaggtcat tacaaaagtt ctatcgtttt ttgctcattt
    13201 tatttgttgc atatattcaa aagaattgtt tcgcaaattc ataagtgcta tactaaagct
    13261 attcttgatg tagaacttag aacaaggagg gagattatct atgaaactat tgtttagaaa
    13321 tcaagcttat cgcctattga ctttgtcacg cttcttcaat gcttttggtg cttcgatttt
    13381 caacctggtc tttatcgtct atgcatcgac cttgccacaa gcatcttttg ctgttgctat
    13441 ggcgaatatt gtcatgattc ttccgaccct ctttacagtt tttgcaggga ttcgggcaga
    13501 ttacacgagg gacaaggtca aatggatggt ctatagcggt ttgtttcagg cggttctatt
    13561 ttttctagca gccctagttg ttcagcaagc tagtctcttt gccttttcta gcctgtgttt
    13621 gatcaatgtc attagtgatg tcatcagtga ttttgcaggt ggcctgcgta tgcctcttat
    13681 taaggaaaaa gtagctgaag atgatttgat ggaggcttat tctttttcac agttcatcac
    13741 ctatatttca gctattggtg gtcaagcttt cggagtctgg ctcttagctc tatcggtcaa
    13801 taatttttct ctcgttgcgg gaatcaatgc ctgctttttc ctagtatcag ccactatcct
    13861 ctttttagga aaaagcaaat tgagcctgtc aatgtcatct gctgatggtg aaaacttaaa
    13921 aaatgagaag ctttctatca aagaccggtt cctaacaatt taccgaaatt tacgtctcgt
    13981 ttttcttaaa agtggacaga aaaactttgg ttttatgctc tttgctgtct tgcttattaa
    14041 ttccttgggt ggcgctttgg gtggaattta taatatcttc tttttgagcc attctctctt
    14101 gaatttttct tatacagagg cactatttat caatcaattc tgtgttttag tagcaatcat
    14161 catcagtagc cttacgggca atgattattt tgggaagcag tccttgccta gattgatgat
    14221 gtgggagacc gtaggactta gtctagttgg tttggctaat ttattcaatc aagtcgtgct
    14281 tggtttgcta tttctcttct ttactctgta tgtgtctggt aaagttcaac caaagattag
    14341 tgccatgctc atgaaaaatc tagctccaga ggttctagct cgtactagta attttttcgg
    14401 tctattgttt accttatcca tacctgtggg aacagcttgt ttttcactag tagccgtatg
    14461 gaacatgcag ttgacttgga tgctatttgt tggtttttcc ttgctagcta tttttttaac
    14521 aattcttaat ctcaaaaatg atatctaaat cctaattttt ttcttactgt tttaatccct
    14581 ctatttatgg taaaataaga ctattaagtt taaagaggat tccctatgaa attacaaaaa
    14641 ccaaaaggaa cgcaggatat tttacctgct gagtctgcta agtggcagta cgttgagggc
    14701 tttgcccgtg aaattttcaa gcgctacaac tacgcagaag tgcgtacgcc tattttcgag
    14761 cattacgagg ttatcagccg ctctgtcgga gatacaacgg atatcgtaac caaggaaatg
    14821 tacgatttct atgacaaggg tgaccgccat attaccctcc gtccagaagg aactgcgccc
    14881 gttgtccgtt cctatgtgga aaataaactc ttcgccccag aagtgcaaaa gccaagcaag
    14941 ttctactaca tgggacctat gttccgttat gagcgtccac aggcagggcg cttgcgccaa
    15001 ttccaccaga ttggtgttga gtgttttggc tctagcaatc cagctaccga tgtggaaaca
    15061 atcgttatgg cagcccattt tttgaaggaa atcggtattc aaggtgtcaa attgcacctc
    15121 aacactcttg gaaatcctga gagccgtgca gcctaccgcc aagccttgat tgactatttg
    15181 acaccgctca aggagacctt gtctaaggat agccaacgtc gcttggagga aaatcctctt
    15241 cgtgtcttgg actctaagga aaaagaagac aaggtggcag tagagaatgc gccgtctatc
    15301 ttggactttc ttgatgaaga aagccaaact cattttgatg ctgtgcgtca gatgttggaa
    15361 aatcttggag tagattacat catcgatacc aatatggtgc gtggtctgga ctactacaac
    15421 cacaccattt tcgagtttat cacagagatt gagggcaatg acttgacagt ctgtgcgggt
    15481 ggtcgctacg atggtttggt tgcttacttt ggaggccctg aaactgctgg atttggtttt
    15541 gggcttggtg tagagcgcct gcttctcatc cttgaaaaac aaggcgtggc cctccctatc
    15601 gaaaacgccc tagatgtcta tatcgcagtc ttgggtgatg gagcaaatgt caaagcccta
    15661 gaactagtcc aagctcttcg ccaacaaggt ttcaaagcag agcgtgatta cctcaaccgt
    15721 aagctcaaag ctcagttcaa gtcagccgat gtctttgcgg ctaagaccct catcacccta
    15781 ggagagagcg aagtcgaaag cggacaagtg acggtcaaga acaaccaaac ccgagaagaa
    15841 gtgcaagtgt cacttgagac aatcagccaa aacttctcag aaatctttga aaaactagga
    15901 ttttatactc aatgaaagtc aaagagcaaa ctaggaagct agccgcaggt tgctcaaaac
    15961 actgttttga agttatggat agaactgacg aagtcagctc aaaacatggt tttgaggttg
    16021 tagatgaaac tgacgaagtc agtaaccata cctacggcga ggtgaagctg acgtggtttg
    16081 aagagatttt cgaagagtat taatgataga taaagtggtc aggaacttac tcctgacctt
    16141 tttcttttgc aaaatgacaa aaatcataaa ctttttgaca gctatacttg tcaaaaagaa
    16201 aaagatgtgt tacaatgtaa gcaagttaag agaaaagaag aaaggagcta tgatgtgggt
    16261 actagtattt atactattta ttattttctt ttattctaat aattctaaaa aaatcaagaa
    16321 actagagaat aaaatcaaaa aacttgagcg aaaagagaaa ggaaacgcag aaatgtcgag
    16381 attattgcaa gaaatgattg gaaagaaacc aattataacg ggagtgtata ttgggccaga
    16441 taactgggaa gttgtggatg ttgatgagga atgggtaaag ctacgacgtg tagataatac
    16501 gggaaaagaa aaattcaagt tgcaacgtat tgaagatatc caaaccgttg aatttgacgg
    16561 agagtaggtg tgtaacgtgc aactaaaaaa tcgtctaaaa gagcttcgag ctcgcgatgg
    16621 tctcaatcaa accgacctag ccaaactggc aggggtttcc agacagacca ttagcctact
    16681 agaacgggat gagtacaccc catccattat cattgccctg aaaatatctc aaattttcaa
    16741 cgaaacagtc gaatcggtat ttcgtttgga ggaggacgag tgatgaacaa gtataaagtg
    16801 atttattatg tagtggtcat agctttatta gtcagcgtat ttctactgat tgggatggac
    16861 ctaagctggt ttaatcccta tcaaagcgac caatttgttt gggtctactt tgctctcatc
    16921 ccagtaattg aatggattga aaagaaatcc aaaaatctag caagtgaaaa aggagaatga
    16981 atatgaaaaa gaaacgtaga ttgttatttt tgatgtctat tgtcttttgg ggggtcttgg
    17041 gcatgtttgt agggatgttt aaggcacgtg tcgaatccca cgaaattatt ttagatgtaa
    17101 aagccttgat gccatggata tcagctattt gtttactgat aggtttcatt agtatgtttt
    17161 tgactttcaa tttcttaaag aaaagcagaa aatttcattc cttgtatcaa gaggaaatgg
    17221 atgacgatct gaatgaaacc tattatgtgc aaatgtatcg gaatcttgag tttggaacca
    17281 ttgcttttaa tattacaggt gtagcgattc cattggctat ttttatttca ttaagtgagg
    17341 tgattatatt gcatacaaac cctcaaacat ttttcctttc tttcttactc tttgtggtat
    17401 tcttagtcgc tcaaaaatct ctttttaaaa ccattgcgat tgttcgtcag tttgatttgg
    17461 aatttttcgc tacaccaaag gatgtcttga actatataaa ttcttatgat gaaggggagc
    17521 gtcaggctaa tttggaacag agttttcgaa ttttattcca attacaccaa tatgtcttac
    17581 cagccttata tatttttctt attatcattt ctttcttgac aggagagatt cagttactag
    17641 ctttcttgct tgtaggagcc atccatgttt atatcaatgt gatgcagtta cctatggtaa
    17701 aacgttattt caaataaagg agttatctat gaaattactt aaaaaccttg gctggattct
    17761 tctagccctt ctatcctttt tctttatcta tggctttatt caggggctcg cgactgcgtc
    17821 gcttgcttta ggcgcttcac cctatgctgt tactctactc tatgtggtct tggctggagt
    17881 atatgtgtac ggcatttaca aatggtatca gaaagctcct gtttatattg agaagagcgg
    17941 ctttaaccga tttatttggc ttcctgcctt ggtttggttc ttatctctgg tcgttcaatt
    18001 cttcttgcca gatgatcctt cagtaaatca gcaaatagcg acagacttga ccttgtctca
    18061 accacttttc tcattctttg ctgtggttat ttttgctcct ttgacggaag agattgtttt
    18121 tagagggatg ttagcacgct atctctttcc taagcaggac aatagtaaac gaaccctgat
    18181 ttttcttctg gtatctagtc ttctatttgc cttgattcat tttccaggtg atgtgcaaca
    18241 attttttgtc tattttagcc ttggttttag tttgggtttg gcttacgtta gcagaaaagg
    18301 tctggtctac agtatttctc ttcacgcttt gaataattta gtcggctttt tgatgattct
    18361 catgctataa tagagtcagg aggtcacatg aaacgagtaa ttttattagc agtgattcag
    18421 gcagtcgttc tatttttcat cattggagcg ctagcttatg ccttcaaagg cgatttcttc
    18481 tataactatc tagcagttgt ctttgctcct attgcaggtg tactgcgttt tgggacggct
    18541 tacataacgg aaattgtctt gcctcgaaag gcagccgaaa tcgctgaaaa gcgtaaagca
    18601 ggcaaaaatt caaaataaaa gagtccggtg aagttcatcg gatttttgta ttatactcaa
    18661 tgaaaatcaa agagcaaact aggaagctag ccgcaggttg ctcaaaacac tgttttgagg
    18721 ttgtggatag aactgacgaa gtcagctcaa aacatggttt tgaggttgta gatgaaactg
    18781 acgaagtcag taacaatacc tacggtaagg cgacgctgac gtggtttgaa gagattttcg
    18841 aagagtatta gcgctaattt ttagggcttt cacctgactt ttaaagactg gcaaactttt
    18901 ctgatgattt tcatgaagag cctgcgcttt tatggtaaaa tagtaacaga ataaaagagg
    18961 agagaaataa tgaaacgtag tatgtatgct ggtcgtgttc gtgaggaaca catcggacaa
    19021 gaaataacct tgaaaggatg ggttggccgt cgtcgtgacc ttggtggttt gatctttatc
    19081 gatcttcgtg accgtgaagg aatcatgcag ttggttatca accctgaaaa agtatctgca
    19141 gaggttatgg caacagctga aagccttcgt agcgaatttg ttattgaggt gactggtcag
    19201 gtcgctgcgc gtgagcaagc caatgataag ttgccaactg gtgcggttga gttaaacgtg
    19261 acagctctta ttgtgcttaa cacagctaag acaacaccat ttgagattaa ggatggcatt
    19321 gaggcaaatg acgatacacg tttgcgttac cgttaccttg accttcgtcg tccagaaatg
    19381 ttggaaaatc ttaaacttcg tgccaaggtg acccactcta tccgcaacta tttggatgag
    19441 ttggagttta tcgacgtgga gacaccattc ctttctaagt caacgcctga aggggcgcgt
    19501 gattatttag tgccgtctcg tgttaataag gggcattttt acgctcttcc tcaaagtcca
    19561 caaatcacga aacagctttt gatgaatgct ggttttgacc gttactacca aatcgttaaa
    19621 tgtttccgtg acgaggactt gcgtggagac cgccagcctg aatttactca ggtcgacttg
    19681 gaaacgtcct tccttactga gcaagaaatc caagatatta cagaaggctt gatcgcgcgc
    19741 gtgatgaagg aaacaaaagg catcgaagta acgctaccat tccctcgtat gaaatacgat
    19801 gatgctatgg ctctttacgg ttctgacaag ccagatactc gttttgacat gttgcttcag
    19861 gacttgacag aagtggtcaa aggtgtagac tttaaagtct tttcagaagc acctgctgta
    19921 aaagcgattg tggtcaaagg agctgcggac aactattcac gtaaagacat cgacaagatg
    19981 acggaagtag ccaaacagta tggtgccaaa ggtcttgctt gggtcaaggt ggttgatgga
    20041 gaattaaacg gaccagttgc caagttcttg actggtatcc aagaagaatt gacaacagcg
    20101 cttgttcttg aagataagga cttggttctc tttgtggcgg atacgcttga agtggctaat
    20161 gcaacactgg gtgcccttcg tggacgtatt gctaaagagc ttggcttgat tgataatgat
    20221 aagttcaact tcctttgggt ggttgactgg ccgatgtttg aatggtctga agaagaaggc
    20281 cgctacatga gcgcccacca tcctttcaca cttccacagg aagagactgc tcacgaatta
    20341 gaaggtgatt tggctaaggt tcgtgccatt gcttacgata tcgtcttgaa cggttatgag
    20401 cttggtggtg gtagccttcg tatcaaccaa aaagaccttc aagaacgcat gttcaaggct
    20461 cttggtttct caactgaaga agccaatgac cagtttggtt tccttcttga agccatggac
    20521 tatggtttcc caccacacgg tggtttggct atcgggcttg accgttttgt catgttgctt
    20581 gctggagaag aaaatatccg tgaagtcatt gcctttccta agaacaacaa ggcaactgac
    20641 ccaatgacac aagctccatc aacagtcgct ctcaaacaac tagaggaact cagcttacaa
    20701 gtagaagaag atgaaacaaa caaaacgaat taagcggtgg cgctattatc tgcgccgctt
    20761 tgcttatcag ataaaaattt tacgtgtctt acaaagtatc tctcgagaaa agtatgatga
    20821 gaagatttcg gcctctctgg tctatggttt tttatcagca gtagcagtta atttcttttt
    20881 ccaaccaggg catgtgtatt cgagtggtgc aacaggtctg gcacagatta tctctgcctt
    20941 gagtaatcac tggtttggtt ttcatattcc gatttcgcta agcttctacg ccattaactt
    21001 ccctttgatg gtcttagctt ggtatcagat tggccataag ttcaccgtct ttacctttat
    21061 cacggtatct atgagttcct tctttatcca gtttgtccct gtggcaacct tgacggagga
    21121 tcccattatc aattcccttt ttgggggtgt tgttatgggt ttggggattg gttttgctct
    21181 tcgaaacaat atctccagtg gtgggacgga tatcgtcagc ctgactattc gcaagaaaac
    21241 gggtaagaat gtcggtagta tttctttctt ggtaaatgga actatcatgc tgatagcagg
    21301 tttgaccttt ggttggaaat acgctcttta ttctatgatt accatctttg tctctagccg
    21361 tgtgacagac gcagtcttta ctaagcaaaa gcgtatgcag gccatgattg tgacaaatca
    21421 tccagagaag gtaattgaaa aaatccataa aaaattgcac cgcggagcaa ccatgatcca
    21481 cgatgcagaa ggaacctata atcacgagag aaaggcagtt ttaatcactg tcattacacg
    21541 tgcagagttt aatgaattta aacagattat gacacaagtg gatccaagct cctttgtctc
    21601 tgtctcggaa aatgttcata ttctaggaag atttgttgag atagataatt agtgattaat
    21661 actcttcgaa aatctcttta aaccacgtca gcgtcgcctt gccgtatata tgtt
//
LOCUS       DAVLTT010000030        21446 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLTT010000030 DAVLTT010000000
VERSION     DAVLTT010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21446
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.030"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     misc_feature    79..210
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            226..756
                     /gene="infC"
                     /locus_tag="VYN15_001261"
     CDS             226..756
                     /gene="infC"
                     /locus_tag="VYN15_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV1452577.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            789..989
                     /gene="rpmI"
                     /locus_tag="VYN15_001262"
     CDS             789..989
                     /gene="rpmI"
                     /locus_tag="VYN15_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV1452578.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            1041..1400
                     /gene="rplT"
                     /locus_tag="VYN15_001263"
     CDS             1041..1400
                     /gene="rplT"
                     /locus_tag="VYN15_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV1452579.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            1458..1838
                     /locus_tag="VYN15_001264"
     CDS             1458..1838
                     /locus_tag="VYN15_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1452580.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDTFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            2088..2888
                     /locus_tag="VYN15_001265"
     CDS             2088..2888
                     /locus_tag="VYN15_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV1452581.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            2899..3837
                     /locus_tag="VYN15_001266"
     CDS             2899..3837
                     /locus_tag="VYN15_001266"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV1452582.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAKAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            3879..5912
                     /locus_tag="VYN15_001267"
     CDS             3879..5912
                     /locus_tag="VYN15_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEV1452583.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDYHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSTDGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(5973..7628)
                     /gene="pavA"
                     /locus_tag="VYN15_001268"
     CDS             complement(5973..7628)
                     /gene="pavA"
                     /locus_tag="VYN15_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV1452584.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            7733..8230
                     /gene="ybeY"
                     /locus_tag="VYN15_001269"
     CDS             7733..8230
                     /gene="ybeY"
                     /locus_tag="VYN15_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV1452585.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            8211..8606
                     /locus_tag="VYN15_001270"
     CDS             8211..8606
                     /locus_tag="VYN15_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV1452586.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            8623..9522
                     /gene="era"
                     /locus_tag="VYN15_001271"
     CDS             8623..9522
                     /gene="era"
                     /locus_tag="VYN15_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV1452587.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            9571..10395
                     /gene="mutM"
                     /locus_tag="VYN15_001272"
     CDS             9571..10395
                     /gene="mutM"
                     /locus_tag="VYN15_001272"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV1452588.1"
                     /translation="MPELPEVETVCRSLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            10395..11000
                     /locus_tag="VYN15_001273"
     CDS             10395..11000
                     /locus_tag="VYN15_001273"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV1452589.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRKQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            10987..12186
                     /locus_tag="VYN15_001274"
     CDS             10987..12186
                     /locus_tag="VYN15_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV1452590.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQIENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            12186..12335
                     /gene="rpmG"
                     /locus_tag="VYN15_001275"
     CDS             12186..12335
                     /gene="rpmG"
                     /locus_tag="VYN15_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1452591.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            12375..12608
                     /gene="secG"
                     /locus_tag="VYN15_001276"
     CDS             12375..12608
                     /gene="secG"
                     /locus_tag="VYN15_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV1452592.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            12710..15064
                     /gene="rnr"
                     /locus_tag="VYN15_001277"
     CDS             12710..15064
                     /gene="rnr"
                     /locus_tag="VYN15_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV1452593.1"
                     /translation="MKDRIKEYLQDKGKMTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVLSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEITTQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            15027..15494
                     /gene="smpB"
                     /locus_tag="VYN15_001278"
     CDS             15027..15494
                     /gene="smpB"
                     /locus_tag="VYN15_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV1452594.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            15510..16370
                     /gene="tehB"
                     /locus_tag="VYN15_001279"
     CDS             15510..16370
                     /gene="tehB"
                     /locus_tag="VYN15_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV1452595.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            16443..17396
                     /gene="coiA"
                     /locus_tag="VYN15_001280"
     CDS             16443..17396
                     /gene="coiA"
                     /locus_tag="VYN15_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV1452596.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            17415..19217
                     /gene="pepF"
                     /locus_tag="VYN15_001281"
     CDS             17415..19217
                     /gene="pepF"
                     /locus_tag="VYN15_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1452597.1"
                     /translation="MVLQRNEINEKDTWDISTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKVMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            19219..19932
                     /locus_tag="VYN15_001282"
     CDS             19219..19932
                     /locus_tag="VYN15_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV1452598.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPKAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            19999..20940
                     /gene="prsA"
                     /locus_tag="VYN15_001283"
     CDS             19999..20940
                     /gene="prsA"
                     /locus_tag="VYN15_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV1452599.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(21057..21398)
                     /locus_tag="VYN15_001284"
                     /pseudo
     CDS             complement(21057..21398)
                     /locus_tag="VYN15_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         6517 a         3961 c         4815 g         6153 t
ORIGIN      
        1 caaaatacaa acacaaactt ttcaaaaaat aactttttat cttgacaaga gctagaaaac
       61 ttggtatcat ataaaagttg agaaaagcag aagtgagagc ttctcgcctt gtgacattaa
      121 gttgcctggc cctacggatg aaaagtttcg aagaaacgct atcataacgt gcgggcttgt
      181 atatttacga gtccgctatt gtttttctct aataaaacaa aagaggtgaa aaccatagca
      241 aagcaagact tattcatcaa tgatgagatt cgtgtacgtg aagttcgctt gattggtctt
      301 gagggagaac agctaggcat caagccactc agtgaagcgc aagctttggc tgataacgct
      361 aatgttgacc tagtattgat tcaaccccaa gccaaaccgc ctgttgcaaa aattatggac
      421 tacggtaagt tcaaatttga gtaccagaag aagcaaaaag aacaacgtaa aaaacaaagc
      481 gttgttactg tgaaagaagt tcgtctaagt ccaacaattg acaagggtga ctttgataca
      541 aaacttcgta atgcacgtaa gttccttgaa aaaggaaata aagttaaggt atctattcgc
      601 tttaagggtc gtatgattac ccataaagag attggtgcaa aagttttagc cgagtttgct
      661 gaagcaactc aagatattgc catcatcgaa caacgtgcta aaatggatgg acgtcaaatg
      721 ttcatgcaat tggcgccagc gactgacaaa aaataattgt cagaaagtta aataaaggag
      781 aaaaaatcat gccaaaacaa aaaacacacc gcgcatcagc taaacgtttc aaacgtacag
      841 gttctggtgg acttaaacgt ttccgtgctt acacttctca ccgtttccac ggaaaaacta
      901 agaaacaacg tcgtcatctt cgtaaagcat ctatggtgca ttcaggagat tacaaacgta
      961 tcaaagcaat gcttactcgc ttgaaataat agcttgactg taagtaaaca attctagaaa
     1021 atatttggag gaaataaaac atggcacgtg ttaaaggtgg cgttgtatca cgcaaacgtc
     1081 gtaaacgtat tcttaaatta gcaaaaggtt actatggagc taaacacatc ttgttccgta
     1141 ctgcaaaaga acaagtaatg aactcttact actatgcata ccgtgaccgt cgtcagaaaa
     1201 aacgtgactt ccgcaaattg tggattactc gtatcaatgc ggcggctcgt atgaacggac
     1261 tttcatactc acaattgatg catggtttga aattggctga gatcgaagtt aaccgtaaaa
     1321 tgcttgctga cttggctgtt aacgatgcag tagctttcac agctcttgca gatgcagcta
     1381 aagcaaaact tggtaaataa caactgatga gactggaaca ggattgtcca gtctttttaa
     1441 aaataaagga gaaagatatg gcttcaaaaa tgctacacac ttgcttacga gtagaaaatc
     1501 ttgaaaaatc aatcgcattt tatcaagata cttttggttt taaagaattg cgtcgcagag
     1561 attttccaga ccatgccttc acgattgtct atctaggtct tgagggtgat gattatgagt
     1621 tggagttgac ttataactac gatcacggtc cgtatgtggt tggtgatggg tttgcccata
     1681 tcgccctcag tacacctgat cttgaggcac ttcatcaaga acacagtgca aaaggctatg
     1741 aagtgactga gccaaatggt ctaccaggaa ctacaccaaa ctattacttt gttaaagacc
     1801 ctgatggata taaggtcgaa gtcattcgtg aaaaataatt tcgtgcaagt taagtagaat
     1861 attcgttttc tacttgactt tttttagctg aaagagtata ctaataaaaa ttcaaccttt
     1921 aaggggagtc cagagagact cacaaggtgt cagataaaag aatagtgcaa ttttctagag
     1981 gagacctttt gagtgtgctc tcttgtgttg tacgatttta actgaggcct tgcactagca
     2041 aggtcttttc tttatctggt ccccttaaaa tttaaggagg aaaagttatg aatctcacat
     2101 gtaagaagcg tttgggtgtc attcggttgg aaaccatgaa ggtggttgca caagaggaaa
     2161 tcgcgccagc aatctttgaa ttagtcctag aaggagaaat ggttgaagcc atgcgagcag
     2221 gccaatttct tcatctgcgt gtaccggacg atgcccatct cttacgtcgt cctatttcaa
     2281 tttcgtctat tgacaaggca aacaagcagt gtcacctcat ttatcggatt gagggagctg
     2341 ggactgcaat tttttcaacc ttaagtcagg gagacactct tgatgtgatg gggcctcagg
     2401 gaaatggttt tgacttgtct gaccttgatg agcagaatca ggttctcctt gttggtggtg
     2461 ggattggtgt tccacccttg cttgaggtgg ccaaggaatt gcatgaacgt ggagtgaaag
     2521 tagtgacagt cctcggtttt gctaataagg atgctgttat tttgaaaacg gaattggctc
     2581 agtatggtca ggtctttgta acgacagatg atggttctta tggcatcaag ggaaatgttt
     2641 ccgttgttat caatgattta gatagtcagt ttgatgctgt ttactcgtgt ggggctccag
     2701 gaatgatgaa gtatatcaat caaacctttg atgatcaccc aagagcctat ttatctctgg
     2761 aatctcgtat ggcttgtggg atgggagctt gctatgcctg tgttctaaaa gtaccagaaa
     2821 gcgagacggt cagccaacgc gtctgtgaag atggtcctgt tttccgcaca ggaacagttg
     2881 tattataagg agaaaattat gactacaaat cgattacaag tgtctctacc tggtttggat
     2941 ttgaaaaatc cgattattcc agcatcaggc tgttttggct ttggacaaga gtatgccaag
     3001 tactatgatt tagacctttt aggttctatt atgatcaagg cgacaaccct tgaaccacgt
     3061 tttgggaatc caactccaag agtggcagag acgcctgctg gtatgctcaa tgcaattggc
     3121 ttgcaaaatc ctggtttaga ggttgttttg gctgaaaagc taccttggct ggaaagagaa
     3181 tatccaaatc ttcctattat tgccaatgta gctggttttt caaaacaaga gtatgcagct
     3241 gtttctcatg ggatttccaa ggcaactaat gtaaaagcta tcgagctcaa tatttcttgt
     3301 cccaatgttg accactgtaa tcatggactt ttgattggtc aagatccaga tttggcttat
     3361 gatgtggtga aagcagctgt ggaagcctca gaagtgccag tttatgtcaa attaaccccg
     3421 agtgtgaccg atatcgttac tgtcgcaaaa gctgcagaag atgcgggagc aagtggcttg
     3481 accatgatca atactctggt tggaatgcgc tttgacctca aaaccagaaa accaatcttg
     3541 gccaatggaa caggtggaat gtcaggtcca gcagtctttc cagtagccct caaactcatc
     3601 cgccaagtag cccaaacaac agacctgcct atcattggaa tggggggagt ggattcggct
     3661 aaagctgccc tagaaatgta tctggctggg gcatctgcta tcggagttgg aacagctaac
     3721 tttaccaatc cttatgcctg ccctgacatc atcgaaaatt taccaaaagt catggataaa
     3781 tacggtatta gcagtctgga agaactccgt caggaagtaa aagagtctct gaggtaaact
     3841 gcaatcaatc tgttcttgat tttttattag tttgtaatat gaatttagga gaattttggt
     3901 acaataaaat aaataagaac agaggaagaa ggttaatgaa gaaagtaaga tttatttttt
     3961 tagctctgct atttttctta gctagtccag agggtgcaat ggctagtgat ggtacttggc
     4021 aaggaaaaca gtatctgaaa gaagatggca gtcaagcagc gaatgagtgg gtttttgata
     4081 ctcattatca atcttggttc tatataaaag cagatgctaa ctatgctgaa aatgaatggc
     4141 taaagcaagg tgacgactat ttttacctca aatctggtgg ctatatggcc aaatcagaat
     4201 gggtagaaga caagggagcc ttttattatc ttgaccaaga tggaaagatg aaaagaaatg
     4261 cttgggtagg aacttcctat gttggtgcaa caggtgccaa agtaatagaa gactgggtct
     4321 atgattctca atacgatgct tggttttata tcaaagcaga tggacagcac gcagagaaag
     4381 aatggctcca aattaaaggg aaggactatt atttcaaatc cggtggttat ctactgacaa
     4441 gtcagtggat taatcaagct tatgtgaatg ctagtggtgc caaagtacag caaggttggc
     4501 tttttgacaa acaataccaa tcttggtttt acatcaaaga aaatggaaac tatgctgata
     4561 aagaatggat tttcgagaat ggtcactatt attatctaaa atccggtggc tacatggcag
     4621 ccaatgaatg gatttgggat aaggaatctt ggttttatct caaatttgat gggaaaatag
     4681 ctgaaaaaga atgggtctac gattctcata gtcaagcctg gtactacttc aaatccggtg
     4741 gttacatgac agccaatgaa tggatttggg ataaggaatc ttggttttat ctcaaatctg
     4801 atgggaaaat agctgaaaaa gaatgggtct acgattatca tagtcaagct tggtactact
     4861 tcaaatccgg tggttacatg acagccaatg aatggatttg ggataaggaa tcttggtttt
     4921 acctcaagtc tgatggcaaa atggctgaaa aagaatgggt ctacgattct catagtcaag
     4981 cctggtacta cttcaaatct ggtggctaca tggcgaaaaa tgagacagta gatggttatc
     5041 agcttggaag cgatggtaaa tggcttggag gaaaagctac aaatgaaaat gctgcttact
     5101 atcaagtagt gcctgtcaca gccaatgttt atgattcaga tggtgaaaag ctttcctata
     5161 tatcgcaagg tagtgtcgta tggctagata aggatagaaa aagtgatgac aagcgcttgg
     5221 ctattactat ttctggtttg tcaggctata tgaaaacaga agatttacaa gcgctagatg
     5281 ctagtaagga ctttatccct tattatgaga gtgatggcca ccgtttttat cactatgtgg
     5341 ctcagaatgc tagtatccca gtagcttctc atctttctga tatggaagta ggcaagaaat
     5401 attattcgac agatggcctg cattttgatg gttttaagct tgagaatccc ttccttttca
     5461 aagatttaac agaggctaca aactacagtg ctgaagaatt ggataaggta tttagtttgc
     5521 taaacattaa caatagcctt ttggagaaca agggcgctac ttttaaggaa gccgaagaac
     5581 attaccatat caatgccctt tatctccttg cccatagtgc cctagaaagt aactggggaa
     5641 gaagtaaaat tgccaaagat aagaataatt tctttggcat tacagcctat gatacgaccc
     5701 cttacctttc tgctaagaca tttgatgatg tggataaggg aattttaggt gcaaccaagt
     5761 ggattaagga aaattatatc gataggggaa gaactttcct tggaaacaag gcttctggta
     5821 tgaatgtgga atatgcttca gacccttatt ggggcgaaaa aattgctagt gtgatgatga
     5881 aaatcaatga gaagctaggt ggcaaagatt agtactataa gtgaatatga tttgagtgaa
     5941 tagtaagtta aaaatcctga tttcaagtaa aatcaggatt ttttcatgga tgcaattttt
     6001 ttggagtctg gtgtgacgcg gagggtcttt tgtcctgtgt aagtgacaaa gccgggtttt
     6061 ccaccagttg gtttattgag ttttttgact tcaatcatat ctacctgcac cagattcgac
     6121 aggcgccctt gagagaagta ggcagctaac tctgctgcgt ctgtcttgac tgcatcagat
     6181 gggtcaagat ttcctgagat gacaacatgg cttccaggaa tgtccttagc atggaaccaa
     6241 agttcctcct tgcgggccat tttaaaggtc aattcctcat tttgaagatt gtttcgtccg
     6301 acatagatga tggttttgcc atcgcttgct agatattgtt ctagtttttt gcgtttctgg
     6361 attttctccc gttgtcttct gcggataaaa cctgtttgaa tcaattcttc acggatttca
     6421 gcgatttctt ccagtccagc ttggttgagg acggtttcta cactttccag atagagaata
     6481 gtggctttgg tttcttcaat caaatcagtc aagtatttga cagcttcttt gagtttctga
     6541 taccgtttaa aatagcgttg ggcattctgg ttgggagtca gagccttatc aagcgcaatc
     6601 atgataggtt ggttggtata gtagttgtct aggataacct ggtcttggtc gttaggcact
     6661 tggtggagga aggttgtcag caattctcct ttttgacgaa attcttcagc gttgtctgtc
     6721 gccagtaact ctttttcctg ttttttgagt ttgtgtcggt ttttctgaag ttcattttca
     6781 acacgacgaa tcagttcact ggcctgctgt ttgacgcggt cgcgctcagc cttatcctta
     6841 tagtaggtgt ccaacaaatc agaaagattt gcaaaaggct ctcccacctg atttgcaaaa
     6901 ggaactggac tgaaggaagt ctcagtcaag catggcttgg tttcttgatt gaaaaaattt
     6961 cggaaagcgg aaagtttttc actaaccagt atcctttcca attcatttgc cgtatcgcgt
     7021 cccagacctt gaaagaggct ttgaagattt tttgctgtta gttcttgggt ttgcaggatt
     7081 tcaaagagct tttcatcctt tatagtaaaa ggattgagag attttgtact tggcggagcg
     7141 atataggtcg atcctggaag taaggtgcgg tagctatttt gtgaaaagcc gacgtgtttg
     7201 ataacttcga ggattttatg actgctttta tcgaccagta gaatattact gtgtttcccc
     7261 ataatttcga taatcaaggt agcctggata tggtctccaa tctcgttttt attggaaact
     7321 gtaatttcca caatacggtc attttccact tgctcaatcg actcaatcag ggccccctgc
     7381 aaatactttc tcaaaaccat gataaaggta gaaggttggg ctggattttc aaaagtcgtt
     7441 tgggtcagct gaatgcgtcc aaaaactgga tgggcagaaa ggagcaggcg atggctttgg
     7501 cgattgctgc ggatttgcaa gaccaactct tgttcaaaag gctgattgat tttctggatg
     7561 cgaccattca ctaattcgct tcgcaattcc tcaactatgt ggtgtaaaaa aaatccgtca
     7621 aatgacatcg ttctctcctt gtgattgtat tccatagtat tatatcaaaa aggtagaata
     7681 aaatcatgga aatgtggtat aataaagcca agtaaagaga aacgagaagc acatgtatat
     7741 tgaaatggta gatgaaactg gtcaagtttc aaaagaaatg ttgcaacaaa cccaagaaat
     7801 tttggaattt gcagcccaaa aattaggaaa agaagacaag gagatggcag tcacttttgt
     7861 gaccaatgag cgtagtcatg aacttaatct ggagtaccgt gacaccgacc gtccgacaga
     7921 tgtcatcagc cttgagtata aaccagaatt ggaaattgcc tttgacgaag aggatttgct
     7981 tgaaaatcca gaattggcag agatgatgtc tgagtttgat gcctatattg gggaattgtt
     8041 catctctatc gataaggctc atgagcaggc cgaagaatat ggtcacagct ttgagcgtga
     8101 gatgggcttc ttggcagtac acggcttttt acatattaac ggctatgatc actacactcc
     8161 ggaagaagaa gcggagatgt tcggtttaca agaagaaatt ttgacagcct atggactcac
     8221 aagacaataa acgaaaatgg aaaaatcgtg acttgatatc cagtttagaa tttgctttga
     8281 caggtatttt tactgctatc aaggaagaac gcaatatgcg aaaacacgca gtgacggctc
     8341 tagtggtcat ccttgcaggt tttggttttc aggtgtcacg aatcgaatgg ctctttctcc
     8401 tattgagtat tttcttggta gtagcctttg agattatcaa ctctgctatt gaaaatgtgg
     8461 tggatttggc cagtcactat cacttttcca tgctggctaa aaatgccaag gatatggcgg
     8521 ctggcgcggt attagtggtt tctcttttcg cagccttaac aggcgcattg atttttctcc
     8581 cacgaatctg ggatttatta ttttaaacag taagaggaaa ttatgacttt taaatcaggc
     8641 tttgtagcca ttttaggacg tcccaatgtt gggaagtcaa cctttttaaa tcacgttatg
     8701 gggcaaaaga ttgccatcat gagtgacaag gcgcagacaa cgcgcaataa aatcatggga
     8761 atttacacga ctgataagga gcaaattgtc tttatcgaca caccagggat tcacaaacct
     8821 aaaacagctc tcggagattt catggttgag tctgcctaca gtacccttcg cgaagtggac
     8881 accgttcttt tcatggtgcc tgctgatgaa gcgcgtggta agggggacga tatgattatc
     8941 gagcgtctca aggctgccaa ggttcctgtg attttggtgg tgaataaaat cgataaggtc
     9001 catccagacc agctcttgtc tcagattgat gacttccgta atcaaatgga ctttaaggaa
     9061 attgttccaa tctcagccct tcagggaaat aacgtgtctc gtctagtgga tattttgagt
     9121 gaaaatctgg atgaaggttt ccaatatttc ccgtctgatc aaatcacaga ccatccagaa
     9181 cgtttcttag tttcagaaat ggttcgcgag aaagtcttgc acctaactcg tgaagagatt
     9241 ccgcattctg tagcagtagt tgttgactct atgaaacgag acgaagagac agacaaggtt
     9301 cacatccgtg caaccatcat ggtcgagcgc gatagccaaa aagggattat catcggtaaa
     9361 ggtggcgcta tgcttaagaa aatcggtagc atggcccgtc gtgatatcga actcatgcta
     9421 ggagacaagg tcttcctaga aacctgggtc aaggtcaaga aaaactggcg cgataaaaag
     9481 ctagatttgg ctgactttgg ctataatgaa agagaatact aagtagaggt aggctcatgc
     9541 ctgcttcttg tttttacaga aggaggactt atgcctgaat tacctgaggt tgaaaccgtt
     9601 tgtcgtagct tagaaaaatt gattatagga aagaagattt cgagtataga aattcgctac
     9661 cccaagatga ttaagacgga tttggaagag tttcaaaggg aattgcctag tcagattatc
     9721 gagtcaatgg gacgtcgtgg aaaatatttg cttttctgcc tgacagacaa ggtcttgatt
     9781 tcccatttgc ggatggaggg caagtatttt tattatccag accaagtgcc tgaacgcaag
     9841 catgcccatg ttttcttccg gtttgaagat gggggcacgc ttgtttatga ggatgtacgc
     9901 aagtttggaa ccatggaact cttggtgcct gaccttttag acgcctactt tatttctaaa
     9961 aaattaggtc ctgaaccaag cgaacaagac tttgatttac aggtctttca atctgccctt
    10021 gccaagtcca aaaagcctat caaatcccat ctcctagacc agaccttggt agctggactt
    10081 ggcaatatct atgtggatga ggttctctgg cgagctcagg ttcatccagc tagatcttcc
    10141 cagactttga cagcagaaga agcgacagct attcatgacc aaaccattgc tgttttgagc
    10201 caggctgttg aaaaaggcgg ttccaccatt cggacctata ccaatgcctt tggggaagat
    10261 ggaagcatgc aggattttca tcaggtctat gataagactg gtcaagaatg tgtacgctgt
    10321 ggtaccatca ttgagaaaat tcaactaggc ggacgaggca cccacttttg tccaaactgt
    10381 caaaggagag actgatgaga aaaatcatcg gaatcactgg gggaattgcc tctggtaagt
    10441 caactgtgac aaattttcta agaaagcaag gctttcaagt agtggatgcc gacgcagtcg
    10501 tccaccaact acagaaacct ggtggtcgtc tgtttgaggc tctagtacag cactttgggc
    10561 aagaaatcat tcttgaaaac ggagaactca atcgccctct cctagctagt ctcatctttt
    10621 caaatcctga agagcaaaaa tggtcgaagc aaattcaagg ggagattatc cgtgaggaac
    10681 tggctacttt gagagaacag ttggctcaga cagaagagat tttcttcatg gatattcccc
    10741 tactttttga gcaggactac agcgattggt ttgctgagac ttggttggtc tatgtggacc
    10801 gagatgccca agtagaacgc ttaatgaaaa gggaccagtt gtccaaagat gaagctgagt
    10861 ctcgtctggc agcccagtgg cctttagaaa aaaagaaaga tttggccagc caggttcttg
    10921 ataataatgg caatcagaac cagcttctta atcaagtgca tatccttctt gagggaggta
    10981 ggcaagatga cagagattaa ctggaaggat aatctgcgta ttgcctggtt tggtaatttt
    11041 ctgacaggag ccagtatttc tttggttgta ccttttatgc ccatcttcgt ggaaaatcta
    11101 ggtgtaggga gtcagcaagt cgctttttat gcaggcttag caatttctgt ctctgctatt
    11161 tccgcggcgc tcttttctcc tatttggggt attcttgctg acaaatacgg ccgaaaaccc
    11221 atgatgattc gggcaggtct tgctatgact atcactatgg gaggcttggc ctttgtccca
    11281 aatatctatt ggttaatctt tcttcgttta ctaaacggtg tatttgcagg ttttgttcct
    11341 aatgcaacgg cactgatagc cagtcaggtt ccaaaggaga aatcaggctc tgccttaggt
    11401 actttgtcta caggcgtagt tgcaggtact ctaactggtc cctttattgg tggctttatc
    11461 gcagaattat ttggcattcg tacagttttc ttactggttg gtagttttct atttttagct
    11521 gctattttga ctatttgctt tatcaaggaa gattttcaac cagtagccaa ggaaaaggct
    11581 attccaacaa aggaattatt tacctcggtt aaatatccct atcttttgct caatctcttt
    11641 ttaaccagtt ttgtcatcca attttcagct caatcgattg gccctatttt ggctctttat
    11701 gtacgcgact tagggcagat agagaatctt ctttttgtct ctggtttgat tgtgtccagt
    11761 atgggctttt ccagcatgat gagtgcagga gtcatgggca agctaggtga caaggtgggc
    11821 aatcatcgtc tcttggttgt cgcccagttt tattcagtca tcatctatct cctctgtgcc
    11881 aatgcctcta gcccccttca actaggactc tatcgtttcc tctttggatt gggaaccggt
    11941 gccttgattc ccggggttaa tgccctactc agcaaaatga ctcccaaagc cggcatttcg
    12001 agggtctttg ccttcaatca ggtattcttt tatctgggag gtgttgttgg tcccatggca
    12061 ggttctgcag tagcaggtca atttggctac catgctgtct tttatgcgac gagcctttgt
    12121 gttgccttta gttgtctctt taacctgatt caatttcgaa cattattaaa agtaaaggaa
    12181 atctagtgcg agtaaaaatc aatctcaaat gctcctcttg tggcagtatc aattacctaa
    12241 ccagtaaaaa ttcaaaaacc catccagaca agattgaggt tttaaagtat tgtcccaagg
    12301 aaagaaaagt aaccctacat cttgaatcta agtagatttt atggtaaaat aatagggatt
    12361 ttaaggagtt tgatatgtat aacctattat taaccatttt attagtatta tctgttgtga
    12421 ttgtgattgc aattttcatg caaccaacca aaaaccaatc cagcaatgta tttgatgcca
    12481 gttcaggtga tttgtttgaa cgcagtaaag ctcgcggttt tgaagctgta atgcagcgtt
    12541 tgacagggat tttagtcttt ttctggctag ccattgcctt agcattgacg gtattatcaa
    12601 gtagataaga aaataatggg caggactagg tctttgcctc tttttatttt taaaggatgt
    12661 ttgagaaggt tttacagtaa aagaaaatta aaaaatctag aaagaaaata tgaaagatag
    12721 aataaaagaa tatttacaag acaagggaaa gatgactgtt aatgatttgg ctcaggcttt
    12781 gggaaaagac agttccaagg attttcgtga gttgattaaa accttgtcct taatggaaag
    12841 aaagcaccaa attcgttttg aagaagatgg tagtctgaca ttagaaatta agaaaaaaca
    12901 tgagattacc ctcaagggga tttttcatgc ccataaaaat ggctttggct ttgttagtct
    12961 ggaaggcgag gaggacgacc tttttgtagg gaaaaatgat gtcaactatg ctattgatgg
    13021 tgataccgtc gaggtagtga ttaagaaagt cgctgaccgc aataagggaa cagcagcaga
    13081 agccaaaatt attgatatcc tagaacacag tttgacaaca gttgtcgggc aaatcgttct
    13141 ggatcaggaa aagcctaagt atgctggcta tattcgttca aaaaatcaga aaatcagtca
    13201 accgatttat gttaagaaac cagccctaaa gttagaagga acagaagttc tcaaggtctt
    13261 tatcgataaa tacccaagca agaaacatga tttctttgtc gcgagtgttc tcgatgtagt
    13321 gggacactca acggatgtcg gaattgatgt tcttgaggtc ttggaatcaa tggacattgt
    13381 atccgagttt ccagaagctg ttgttaagga agcagaaagt gtgcctgatg ctccgtctca
    13441 aaaggatatg gaaggtcgtc tggatctaag agatgaaatt acctttacca ttgacggtgc
    13501 ggatgccaag gacttggacg atgcagtgca tatcaaggct ctgaaaaatg gcaatctgga
    13561 gcttggggtt cacatcgcag atgtttctta ttatgtgacc gaggggtctg cccttgacaa
    13621 ggaagccctt aaccgtgcga cttctgttta cgtgacagac cgagtggtgc caatgcttcc
    13681 agaacgacta tcaaatggca tctgctctct caatccccaa gttgaccgcc tgacccagtc
    13741 tgctattatg gagattgata aacatggtcg tgtagtcaac tataccatta cacaaacagt
    13801 tatcaagacc agttttcgta tgacctatag cgatgtcaat gatatcctag ctggcgatga
    13861 agaaaagaga aaagaatatc ataaaattgt attaagtatc gaactcatgg ccaagcttca
    13921 tgaaacttta gaaaacatgc gtgtgaaacg tggagctctc aattttgata ccaatgaagc
    13981 gaagatttta gtggataaac aaggtaagcc tgttgatatc gttcttcggc agcgtggtat
    14041 tgccgagcgg atgattgagt cttttatgtt gatggctaat gaaacagttg ccgaacattt
    14101 cagcaagttg gatttgcctt ttatctatcg aattcacgag gagcctaagg ctgaaaaggt
    14161 tcagaagttt attgattatg cttcgagttt tggcttgcgc atttatggaa ctgccagtga
    14221 gattagtcag gaggcacttc aggacatcat gcgtgctgtt gagggagaac cttatgcaga
    14281 tgtattgtcc atgatgcttc ttcgctctat gcagcaggct cgttattcgg agcacaatca
    14341 cggccactat ggactagctg ctgactatta tactcacttt accagtccaa ttcgtcgtta
    14401 tccagacctt cttgttcacc gtatgattcg agattacggc tgttctaagg aaatagcaga
    14461 gcattttgaa caagtgattc cagagattac gacccagtct tccaaccgtg aacgtcgtgc
    14521 catagaagct gagcgtgaag tcgaagccat gaaaaaggct gagtatatgg aagaatacgt
    14581 gggtgaagag tatgatgcag ttgtatcaag tattgtcaaa ttcggtctct ttgtcgaatt
    14641 gccaaacaca gttgaaggct tgattcacat cactaatcta cctgaatttt atcatttcaa
    14701 tgagcgtgat ttgactcttc gtggagaaaa atcaggtatc actttccgag tgggtcagca
    14761 gatccgtatc cgtgttgaaa gagcggataa aatgactgga gagattgatt tttcattcgt
    14821 acctagtgag tttgatgtga ttgaaaaagg cttgaaacag tctagtcgta gtggcagagg
    14881 gcgtggttca aatcgtcgtt cggataagaa ggaagacaag agaaaattag gacgctcaaa
    14941 tgataagcgt aagcattcac aaaaagacaa gaagaaaaaa ggaaagaaac ctttttacaa
    15001 ggaagtagct aagaaaggag ccaagcatgg caaagggcga gggaaaggtc gtcgcacaaa
    15061 ataaaaaggc acgccacgac tatacaatcg tagatacgct agaggcaggg atggtcctga
    15121 ctggaactga aatcaagagt gtacgagctg ctcgaattaa tctcaaggat ggctttgctc
    15181 aagtgaaaaa tggagaagtt tggctgagca atgttcatat cgcgccttac gaagagggca
    15241 atatctggaa ccaggaacca gaacgtcgtc gtaaactcct gcttcataaa aagcaaattc
    15301 aaaaattgga acaagagacc aaagggacag gaatgacctt agttcccctt aaggtctata
    15361 taaaagatgg ctacgctaag cttcttttag gacttgccaa agggaagcat gactatgaca
    15421 aacgggagtc tatcaaacgt cgtgagcaaa atcgagatat cgcgcgtgtg atgaaagctg
    15481 ttaatcagcg ataaaaagag gaattgaaaa tggaaaaatt agttgcctat aaacgcatgc
    15541 ctttgtggaa taaacaaaca atgcctgaag ctgttcagca aaagcacaat acaaaagttg
    15601 ggacttgggg gaaaattact gtcttgaagg gagctctcaa gtttattgaa ttgacagaag
    15661 aaggggaagt tctagctgaa cacctctttg aagcaggggc agacaatcca atggcccaac
    15721 ctcaagcctg gcaccgagtg gaagctgcca cagatgatgt ggaatggtac ttggaatttt
    15781 attgtaaacc tgaggattat tttgctaaaa aatacaatac caatcctgtt cattcagagg
    15841 tcctagaggc catgcagaca gtgaaacaag ggaaagcttt ggatttgggt tgtggtcagg
    15901 ggcgtaattc tctttttcta gcccagcaag attttgatgt gacggctgta gatcaaaatg
    15961 gactagctct tgaaatcttg caaagcattg tggagcagga agatttggac atgcctgttg
    16021 gcctttacga tatcaattca gctagcattg aacaagaata tgattttatc gtttcaacag
    16081 ttgttctcat gtttctacaa gcggaccgca ttccagctat tattcaaaat atgcaggaga
    16141 aaaccagtgt tggtggttac aaccttatcg tttgtgccat ggacacggag gattatcctt
    16201 gctcggttaa cttcccattc acctttaaag aaggagaact ggcagactat tacaaggatt
    16261 gggaattggt taagtacaat gaaaatccag gccatttgca ccgtcgcgat gagaatggca
    16321 atcgtattca actacgcttt gcgaccttac tagctaagaa aatcaagtaa acacacatga
    16381 agattaggaa ttttcctgat cttttttctt ttttacgaat gatatagaaa aggagggaat
    16441 tcatgtttgt tgcgagagat gctaggggag aattggtaaa tgtgttagag gataaacttg
    16501 agaagcaagc atacacctgc ccagcttgtg gaggccagct ccatttgcgt caaggaccaa
    16561 gtgtacggac gcattttgcc cataaatcct taaaagactg tgattttttc tttgaaaatg
    16621 aaagtccaga acacctggcc aataaggaat ccctctatca ctggttgaaa aaagagacaa
    16681 aggttcaatt agagtacccg ctttcagaac ttaaacagat tgcggatgta tttgtaaatg
    16741 gcaatctagc tctagaagtt cagtgtagtc ccttgcctca gaaagtcctt aaagagcgaa
    16801 gtgagggcta tcgtagtcag ggttaccaag tactgtggtt gctgggtcaa aaactgtggc
    16861 tcaaggagcg tttgactcgt ctacagcaag gttttctgta tttcagtcaa aacatgggct
    16921 tttatgtttg ggaattagac aaggaaaaac aagttttaag actcaaatac ctgatttacc
    16981 aggatctccg cggtaaactc cattatcaaa tcaaggaatt ttcctatggt caaggtagtt
    17041 tattggaaat attgcgtctt ccctataaga gacaaaaaat atctcatttt acagtttctg
    17101 aggacaagga catctgtcgc tatatccggc aacaacttta ttatcaaaat ctcttttgga
    17161 tgaaagaaca agcagaagcc tatcaaaagg gagaaaatat cctgacttat ggactgaaag
    17221 aatggtatcc acaaattcga ccaatagtgg gcaaattttt ccagattgaa caagacttga
    17281 ctagctatta tcagcacttt tatacctatt accaaaaaaa tcctcaaaat gattggcaaa
    17341 agctttatcc accagccttt tatcagcaat atttcttgaa aaatatggta gaatagaaag
    17401 gatggaggaa tctaatggta ttacaaagaa atgaaataaa tgaaaaagat acatgggata
    17461 tatcaacgat ctacccaact gaccaggctt gggaagaagc cttaaaagat ttaacagaac
    17521 aattggagac agtagcccag tatgaaggcc atctcttgga tagtgcggat aacctactag
    17581 aaatcactga attttctctt gaaatggaac gccagataga gaagctttac gtttatgctc
    17641 atatgaagaa tgaccaggat acacgtgaag ctaagtatca agagtactat gccaaggtca
    17701 tgacactcta cagccagtta gaccaagcct tttcattcta tgagcctgaa tttatggaga
    17761 ttagcgaaaa gcagtatgct gactttttag aagctcaacc aaagctgcag gtttatcaac
    17821 actattttga caagctcttg caaggcaagg atcacgttct ttcacaacgt gaagaagaat
    17881 tattggctgg agctggagaa atctttggtt cagcaagtga aaccttcgct atcttggaca
    17941 atgcggatat tgtgttccct tatgtcctag acgatgatgg taaagaagtt cagctatctc
    18001 atgggactta cacacgtttg atggagtcta aaaaacgtga ggttcgccgt ggtgcctatc
    18061 aagctcttta tgcgacttac gaacaattcc aacacaccta tgccaaaacc ttgcaaacca
    18121 atgttaaggt gcaaaattac cgtgctaaag ttcgtaacta caagagtgct cgtcatgcag
    18181 ccctcgcagc gaattttgtt ccagaaagtg tttatgacaa tttggtagca gcagttcgca
    18241 agcatttgcc actcttacat cgctatcttg agcttcgttc aaaaatcttg gggatttcag
    18301 atctcaagat gtacgatgtc tacacaccgc tttcatctgt tgaatacagt tttacctacc
    18361 aagaagcctt gaaaaaagca gaagatgctt tggcagtctt gggtgaggat tacttgagcc
    18421 gtgttaaacg tgccttcagc gagcgttgga ttgatgttta cgaaaatcaa ggcaagcgtt
    18481 caggtgccta ctctggtggt tcttacgata ccaatgcctt tatgcttctc aactggcagg
    18541 acaatctgga caatctcttt actcttgttc atgaaacagg tcacagtatg cattcaagct
    18601 atactcgtga aactcagcct tatgtttacg gagattactc tatctttttg gctgagattg
    18661 cctcaactac caatgaaaat atcttgacgg agaaattatt ggaagaagtg gaagacgacg
    18721 caacacgctt tgctattctc aataacttcc tagatggttt ccgtggaaca gttttccgcc
    18781 aaactcaatt tgctgagttt gaacacgcca ttcaccaagc agatcaaaat ggggaggtct
    18841 tgacaagcga tttcctaaat aaactctacg cagacttgaa ccaagagtat tatggtttga
    18901 gtaaggaaga caatcctgaa atccaatacg agtgggctcg cattccacac ttctactata
    18961 actactatgt atatcaatat tcaactggct ttgcggccgc ctcagccttg gctgaaaaaa
    19021 ttgtccatgg tagtcaagaa gaccgtgacc gctatatcga ctacctcaag gcaggtaagt
    19081 cggactatcc acttaatgtc atgagaaaag ctggtgttga tatggagaag gaagactacc
    19141 tcaacgatgc ctttgcagtc tttgaacgcc gtttaaatga gtttgaagcc cttgttgaaa
    19201 aattaggatt ggcataaaat ggttgaatcg tatagtaaga atgctaacca taacatgcgt
    19261 cgtcctgtcg tcaaagaaga aattgtagac ttgatgcgtc agcgtcaaaa gcaggtcaca
    19321 ggtttcttga aagaattgga agactttgcc cgcaaggaaa atattcctat tattccccat
    19381 gaaacggttg cttatttccg ttttcttatg gaaaccatgc agcctaaaaa tattctggaa
    19441 attgggacgg ctatcggttt ttcagctctc ttgatggctg aacatgcgcc aaaggctaag
    19501 attacaacta ttgatcgtaa tccagaaatg attggttttg ccaaggaaaa ttttgcccag
    19561 tttgacagtc gcaagcaaat cactctccta gagggagatg cggtggatgt cttatctaca
    19621 ctgacagagt cttatgattt cgtatttatg gattctgcca agtctaaata catcgtcttt
    19681 ctgccagaaa tcctcaaaca tttggaagtt ggtggtgtgg ttgtcttgga tgatattttt
    19741 caaggtggtg atgttgccaa ggatattatg gaagtccgtc gtggtcagcg aaccatttat
    19801 cgaggccttc aaaaattatt tgatgcaacc ttagacaatc cagaactcac cgcaacatta
    19861 gtgcctttag gagatggtat tctcatgctt cgtaaaaatg tagcagatgt tcaactgtct
    19921 gaaagcgaat gattttcaga aaaatttaag aaaaaatagt aaaatagata gagtaacact
    19981 tatctcaaag gagtagacat gaagaaaaaa ttattggcag gtgccatcac actattatca
    20041 gtagcaactt tagcagcttg ttcgaaaggg tcagaaggag cagaccttat cagcatgaaa
    20101 ggggatgtca tcacagaaca tcaattttat gagcaagtga aaaacaaccc ttcagcccaa
    20161 caagtcttgt taaatatgac catccaaaaa gtttttgaaa aacaatatgg ctcagagctt
    20221 gatgataaag aggttgatga tactattgcc gaagaaaaaa aacaatatgg cgaaaactac
    20281 caacgtgtct tgtcacaagc aggtatgact cttgaaacac gtaaagctca aattcgtaca
    20341 agtaaattag ttgagttggc agttaagaag gtagcagaag ctgaattgac agatgaagcc
    20401 tataagaaag cctttgatga gtacactcca gatgtaacgg ctcaaatcat ccgtcttaat
    20461 aatgaagata aggccaaaga agttctcgaa aaagccaagg cagaaggtgc tgattttgct
    20521 caattagcca aagataattc aactgatgaa aaaacaaaag aaaatggtgg agaaattacc
    20581 tttgattctg cttcaacaga agtacctgag caagtcaaaa aagccgcttt cgctttagat
    20641 gtggatggtg tttctgatgt gattacagca actggcacac aagcctacag tagccaatat
    20701 tacattgtaa aactcactaa gaaaacagaa aaatcatcta atattgatga ctacaaagaa
    20761 aaattaaaaa ctgttatctt gactcaaaaa caaaatgatt caacatttgt tcaaagcatt
    20821 atcggaaaag aattgcaagc agccaatatc aaggttaagg accaagcctt ccaaaatatc
    20881 tttacccaat atatcggtgg tggagattca agctcaagca gtagtacatc aaacgaatag
    20941 tccaaatcaa tgagtcaggg aaaaaaactc gacttcagga aaaaatgaag caaacattcc
    21001 cacaataaaa cgcatagtac aaggtttgta ctgaccccaa aagttagaca attaatttat
    21061 ctgaaggatt tagttctgta ttgcacaggg ctaagtcctt ttagttttac cttaattctc
    21121 ttattgttgt aataatcaat atagtctata atggcttgtt ccaattgatt aagtaattta
    21181 aatgttttct catagccata aaacatttcg gattttaaaa tgccaaagaa agattccatc
    21241 ctaccgttgt cttggctgtt tcctttgcgt gacatagatg cttgaattcc cttactctct
    21301 aggaagcgat gataagaatc gtgttggtat tgccagcctt ggtcactatg gagaatcgta
    21361 ttctcgtagt gcttctcttt gaatgcctgt tccaacatta acgatcaatc aatttaatca
    21421 tgtacctaat attagaattg tttatc
//
LOCUS       DAVLTT010000031        21161 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLTT010000031 DAVLTT010000000
VERSION     DAVLTT010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21161
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.031"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..208
                     /locus_tag="VYN15_001285"
     CDS             <1..208
                     /locus_tag="VYN15_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV1452600.1"
                     /translation="AHRLVENTTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEY
                     NYLLTSSELVYLMAHIRRLTKNLD"
     gene            226..2064
                     /locus_tag="VYN15_001286"
     CDS             226..2064
                     /locus_tag="VYN15_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1452601.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDAPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            2077..3492
                     /locus_tag="VYN15_001287"
     CDS             2077..3492
                     /locus_tag="VYN15_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1452602.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDITLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            3974..5020
                     /gene="pheS"
                     /locus_tag="VYN15_001288"
     CDS             3974..5020
                     /gene="pheS"
                     /locus_tag="VYN15_001288"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV1452603.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            5020..5529
                     /locus_tag="VYN15_001289"
     CDS             5020..5529
                     /locus_tag="VYN15_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1452604.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            5606..8011
                     /locus_tag="VYN15_001290"
     CDS             5606..8011
                     /locus_tag="VYN15_001290"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV1452605.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVIQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIVSLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(8079..9080)
                     /locus_tag="VYN15_001291"
     CDS             complement(8079..9080)
                     /locus_tag="VYN15_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1452606.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            9236..9651
                     /locus_tag="VYN15_001292"
                     /pseudo
     CDS             9236..9651
                     /locus_tag="VYN15_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            9777..10043
                     /locus_tag="VYN15_001293"
     CDS             9777..10043
                     /locus_tag="VYN15_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1452607.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            10304..12553
                     /gene="metE"
                     /locus_tag="VYN15_001294"
     CDS             10304..12553
                     /gene="metE"
                     /locus_tag="VYN15_001294"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV1452608.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEANRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            12617..13483
                     /gene="metF"
                     /locus_tag="VYN15_001295"
     CDS             12617..13483
                     /gene="metF"
                     /locus_tag="VYN15_001295"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV1452609.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            14168..16381
                     /gene="pnp"
                     /locus_tag="VYN15_001296"
     CDS             14168..16381
                     /gene="pnp"
                     /locus_tag="VYN15_001296"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV1452610.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            16397..17014
                     /gene="cysE"
                     /locus_tag="VYN15_001297"
     CDS             16397..17014
                     /gene="cysE"
                     /locus_tag="VYN15_001297"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV1452611.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            17026..17910
                     /locus_tag="VYN15_001298"
     CDS             17026..17910
                     /locus_tag="VYN15_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1452612.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGVRDSEV"
     gene            17997..19340
                     /locus_tag="VYN15_001299"
     CDS             17997..19340
                     /locus_tag="VYN15_001299"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV1452613.1"
                     /translation="MIKIYDTMSRDLREFVPIENGKVKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            19333..19719
                     /locus_tag="VYN15_001300"
     CDS             19333..19719
                     /locus_tag="VYN15_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV1452614.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            19723..20607
                     /locus_tag="VYN15_001301"
     CDS             19723..20607
                     /locus_tag="VYN15_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV1452615.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(20654..>21161)
                     /locus_tag="VYN15_001302"
     CDS             complement(20654..>21161)
                     /locus_tag="VYN15_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEV1452616.1"
                     /translation="IMNQFERKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLT
                     NKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPIFQTVFKT
                     FLKNKEKIVNALQLPYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKER
                     TKFVLSRA"
BASE COUNT         6396 a         3872 c         4732 g         6161 t
ORIGIN      
        1 tgcccatcgc ttggttgaaa atacaactta ttgtgacgat gatgatgaag acttgttagc
       61 attaatgaaa aataaatatc ctagagaata tgaatgtggt gaacaggtgg caatgtttat
      121 acaaactgag tacaattatt tgctgacttc tagtgaatta gtttatttga tggctcatat
      181 tcgtcgctta acaaaaaatt tagattaata gaataggaga ataccatgag ttataaagat
      241 aaggtacaaa aaatcctcga tgtaattgga ggtgaaaaaa atgtcaatag agttacccat
      301 tgtgtaacac gtttaagatt agaattaaaa gatgaaaatt tagtcaatga tgatgatgtg
      361 aagaagatac caggtgtaat aggtattatg aaaaagaatg gacaatatca aattatactt
      421 ggtaatgatg tagctaatta ttataaagaa ttcgttaaac ttggcaattt tgaatccgat
      481 tcagttgttc aagggcacaa agggaatatt ttagaaagaa tcattgagta tatcgctggt
      541 tccatgactc caatcattcc agcaatgtta gggggaggta tgctgaaagt cttggtaatt
      601 attttaccaa tgcttggtat attgcaatca gattctcaga ctattgcttt tttgacattt
      661 tttggggatg ctccatatta tttcttaccg ctgttattag cttattctgc atcacaaaaa
      721 ttaaaagtaa catctacatt agctatgtct gtagcaggtg tacttctcca tccaaatttt
      781 gttcaaatgg tgcaatcagg gaatcctctt agtttatttg gtgtacctgt gacaccagct
      841 agttatggtt cgtcagtcgt tccaattctt attatggttt ggttgatgaa atatattgaa
      901 aaaatgattg ctaaattaac accagctgtt actaagagtt ttttgcaacc tacgctagta
      961 ttattagtat caagctgtat tgccttagtt gtagtcggac ctattggagt aattgttggt
     1021 gaaggattat caaatctagt tgggcaaatg tatggtgtag ctggatggct tacattagct
     1081 attcttggtg ctattatgcc atttattgtt atgactggaa tgcattgggc ttttgcacct
     1141 atttttttgg cggcatctat tgctactcca gacgtattaa ttcttccagc aatgttaggg
     1201 tcaaacttag ctcaaggggc tgcttcgatg gctgttgcat taaagagtaa aaataataat
     1261 acaaaacaaa ttgcttttgc agcaggtttc tcagccttac ttgcaggaat taccgaacct
     1321 gcattatatg gtgtgacttt aaaatataaa aaaccgcttt atgcagctat gattggtggt
     1381 ggattagcgg gattatttgc aggtcttact agtgttaaag cgtatctatt tgctgtccca
     1441 tctttgatag cgttgcctca atttatttat tctgatgcac catcaaatat tgtaaatgct
     1501 ttaattgtgg cggtcatttc ggttgttatt acctttgtat tagcttatat atttggaatc
     1561 gatgaagaag agagttctag taatttagaa gttgaagctg gagtttcaaa taaaaaaatg
     1621 atattttctc ctatatcagg agaaatcatt ccgttaagcg atgttcagga taaaacattt
     1681 tcagataaac taattggaga cggagtagcg attatcccaa gtgaaggtaa ggtttatgca
     1741 ccatttgatg ggaaaattac aaatattttt ccgactaagc acgcaattgg attgaagagt
     1801 gatgagggtg ttgagttact aattcatatc ggattagata ctgttgagct aaaaggtcaa
     1861 ggttttatta gtcatgtaga agaaggagac agagttttca aaaatcagtt gatttttgaa
     1921 atggacttaa atttaatcaa gactaaaggc tacgaaacag ttacaccagt aattgtaacg
     1981 aataccaatg attttctaga tgtattagta ttacctaata atcagacaat cgagcattct
     2041 aaggaactac tggtaatatt ataatggagg aaagttatga ccatttttcc agatgatttt
     2101 ctttggggtg gagctgttgc agctaatcaa gtagagggag catataatga agatggtaag
     2161 ggcttatcag ttcaggatgt gttacccaaa ggtggattag gagaagcaac agaaaatcct
     2221 acagaagata acttaaaatt attaggtatt gatttttatc ataaatataa ggaagatata
     2281 accttgtttt ctgaaatggg ctttaatgtt tttcgtactt ctattgcatg gagtagaatt
     2341 tttccaaaag gagatgaaga agaacctaac gaagctggtt tgaaatatta tgatgaattg
     2401 tttgatgaac tacatgctca cgggatagag ccacttgtaa ctctttcaca ctatgagact
     2461 ccattatatt tagcaagaaa atatcatgga tggattgata ggagaatgat tcatttttat
     2521 gaaaaatttg ctcgaacagt tttagaaagg tataaagata aagttaaata ttggcttaca
     2581 tttaacgaag taaactctgt tttggaatta ccgtttacta gtggaggaat agatatacct
     2641 aaggagaatc tttcgaaaca agaattatat caagctatac atcatgaatt agtcgcctcg
     2701 agtttggtta caaaaattgc tcgtgagatt aattcagagt ttaaggtggg gtgtatggta
     2761 ttagctatgc cagcttatcc aatgactcca aatccaaaag atgtatgggc gactcatgag
     2821 tatgagaatc taaattatct attttcagat gtgcatgtta gaggttatta tccgaattat
     2881 gcaaaaagat attttaagga acatgacatt aacatagagt ttgcagctga agatgcagag
     2941 ttattaaaaa attatactgt agatttttta tcctttagct attacatgag tgtgactcaa
     3001 tctgctcttc caacacagta taattcagga gaagggaata ttattggtgg tttagtaaat
     3061 ccttatttag agtcttctga gtggggatgg caaattgatc caattggact acgtataatt
     3121 ttaaatagat attatgaccg ttatcaaatt ccattattta tagtggaaaa cggattaggt
     3181 gctaaagatc aactaataaa agatgaattt aataacttaa cagtccaaga tgattataga
     3241 attcagtata tgaaagaaca tttattgcaa gtagctgaag ctctacaaga tggtgtggaa
     3301 attatgggct atacgtcttg gggatgtatt gactgcgttt ctatgtccac tgcacagctt
     3361 tctaagaggt acggtctcat ttatgttgat cgaaatgatg atggaaatgg cacattcaat
     3421 cgatataaga aaatgtcctt tacttggtat aaaggagtga ttgaatcaaa tggagaatcc
     3481 ttattcaaat agttttttat tgatgactag ctattatcac ggttaaggtg gcatttcatt
     3541 aaatatggaa taaagaagtt tggaagacat taaattctaa acttctttat tttatagggg
     3601 agtgtcaatt aatttaattt tgttacaaaa attataaata gttaatttag ataaattgtt
     3661 tatataaatt tagataagaa taagctaaca agcagaagta agataggtct tgcaagaatg
     3721 gtaaaaatct gataaactaa gtagtaattg aataggaatc tgaaagacta gtagcccaag
     3781 ggaagtatat cagggaggag agccgtgact gcaagctctc tatatgaaag ctgggtgaat
     3841 tcacttgcgc atggatttag aaatgaaggt ctgacttgtc agatgaaaac ggatggtacc
     3901 gcgtgtcaac gctccgagtg gagtttttgg catgtggttt tctttttatc tacgagagac
     3961 tgatggagga aatatgtcaa ctattgaaga acaattaaaa gcgcttcgcg aagaaacgct
     4021 gactagcttg aagcagatta ctgctggaaa tgaaaaagag atgcaagatt tgcgtgtctc
     4081 tgtccttggt aaaaagggtt cgctcactga aatcctcaaa gggatgaaag atgtttctgc
     4141 tgagatgcgt ccaatcatcg ggaaacacgt caatgaagct cgtgatgtct tgacagctgc
     4201 ttttgaagaa acagctaagc tcttggaaga aaagaaagtc gcggctcaac tggctagcga
     4261 gagtatcgat gtgacgcttc caggtcgtcc agttgcgact ggtcaccgtc acgttttgac
     4321 acaaaccagt gaagaaatcg aagatatctt catcggtatg ggttatcaag tcgtggatgg
     4381 ttttgaagtg gagcaagact actataactt tgaacgtatg aaccttccaa aagaccaccc
     4441 agctcgtgat atgcaggata ctttctatat cactgaagaa atcttgctcc gtacccacac
     4501 gtctccagtt caggcgcgtg ctatggatgc ccatgatttt tctaaaggtc ctttgaagat
     4561 gatctcgcca gggcgtgtct tccgtcgcga tacggacgat gcgacccaca gtcaccaatt
     4621 ccaccaaatc gaaggcttgg tagttgggaa aaatatctct atggctgatc ttcaaggaac
     4681 gcttcagttg attgtccaaa aaatgtttgg tgaagagcgt caaattcgtt tgcgtccatc
     4741 ttactttcca ttcacagagc catctgttga ggtggatgtt tcttgcttca aatgtggtgg
     4801 agaaggctgt aacgtatgta agaaaacagg ttggatcgaa attatggggg ccggtatggt
     4861 tcacccacgt gtccttgaaa tgagtggtat cgatgcgact gtatactctg gctttgcctt
     4921 tggtcttgga caagagcgtg tagctatgct ccgttatgga atcaacgata tccgtggatt
     4981 ctaccaagga gatgtccgct tctcagaaca gtttaaataa tgattagaaa agtagaaatg
     5041 gcagatgttg aggtgttggc taaaattgcc aaacaaacct ttcgtgaaac ctttgcgtat
     5101 gataatacgg aagagcagtt acaggaatac tttgaagagg cttatagtct gaaaactttg
     5161 tcaactgagt tgggaaatcc tgactctgaa acctatttca ttatgcatga ggaggagata
     5221 gctggttttc tcaaagtcaa ctggggaagt gctcaaactg agagagaatt agaggacgct
     5281 tttgaaattc aacgcctcta tgtgctacaa aaattccaag gatttggact aggtaagcaa
     5341 ctgtttgaat ttgctcttga acttgctaca aaaaatagtt tttcttgggc ttggttaggt
     5401 gtttgggagc ataatacaaa agctcaagcg ttttataacc gatatggttt tgaaaaattt
     5461 agccaacatc attttatggt tggtcaaaaa gtagatacgg attggttact gagaaagaaa
     5521 ttaaggtaag aagatgattc ttctattgaa atgataggaa aggaaaagaa ctagagtgac
     5581 aactgtcatt ctggagaact aaattatgct tgtatcttat aaatggttaa aagaattggt
     5641 ggacattgat gtgccatcac aggagttggc tgaaaaaatg tcaaccacag ggatcgaggt
     5701 cgaaggtgtc gaatcaccag ctgccggtct ttcaaaaatt gtcgtcggtg aggtcttgtc
     5761 ttgcgaagat gtgccagaga ctcacctcca tgtttgtcag gttaacgttg gcgaagaaga
     5821 agcccgtcag atcgtttgtg gtgccccaaa tgtgcgtgct gggatcaagg tcatggtggc
     5881 tcttccagga gctcgtatcg ctgataacta caaaatcaaa aaaggaaaaa tccgtggttt
     5941 ggagtcactt ggaatgatct gttcacttgg tgaattggga atttctgact cagttgtgcc
     6001 taaggaattc gcagatggca tccaaatctt gcctgaagat gccgtgccag gtgaggaagt
     6061 cttttcttac ctagacttgg atgatgaaat catcgaactt tccatcacac caaaccgtgc
     6121 agatgccctt tctatgtgtg gagtggctca cgaagtggca gccatctatg acaaggcagt
     6181 caactttaaa aaatttactc taacagaaac taatgaagct gcggcagatg ccctttctgt
     6241 cagcattgag acagacaagg cgccttacta tgcagctcgt atcttggaca atgtgactat
     6301 cgcaccaagt ccacaatggt tgcaaaacct tctcatgaac gaaggcatcc gtcccatcaa
     6361 taacgttgta gacgtgacaa actacatcct gctctacttt ggtcaaccta tgcatgcttt
     6421 tgacttggac acatttgaag ggactgacat ccgtgtgcgt gaagcgcgtg atggtgaaaa
     6481 attagtgacc ctggacggtg aagaacgaga cttggctgag acagacctcg tgattacagt
     6541 tgctgacaaa ccagtagccc ttgccggtgt tatgggtggt caggctacag aaatttctga
     6601 aaaatctagt cgtgttatcc ttgaagctgc tgtttttaat ggcaaatcta tccgtaagac
     6661 aagtggtcgc ctgaaccttc gttctgagtc atcttctcgc tttgaaaaag gaattaatgt
     6721 ggcaacagtt aatgaagccc ttgatgcggc agctagcatg attgcagagc ttgcaggcgc
     6781 gacggtgcgt aagggtatcg tttcagcggg tgagcttgat acctctgatg tggaagtttc
     6841 ttcaaccctt gctgatgtta accgtgtcct cggaactgag ctgtcttatg ctgatgtaga
     6901 agacgtcttc cgtcgtcttg gctttggtct ttctggaaat gcagacagct ttacagtcag
     6961 cgtaccacgt cgtcgttggg atatcacaat cgaagctgat ctctttgaag aaatcgctcg
     7021 tatctatgga tatgaccgct tgccaaccag ccttccaaaa gacgatggta cagctggtga
     7081 attgactgtg atacaaaaac tccgccgtca agttcgtacc attgctgaag gagcaggttt
     7141 gacagaaatc atcacctatg ctctgacaac tcctgaaaaa gcagttgagt tcacagctca
     7201 accaagtaac cttactgaac tcatgtggcc aatgactgtg gatcgttcag tcctccgtca
     7261 aaatatgatt tcagggatcc ttgataccgt tgcctacaac gtggctcgta agaataaaaa
     7321 cttggccctt tatgagattg gaaaagtctt tgaacaaaca ggtaatccaa aagaagaact
     7381 tccaaatgag atcaacagct ttgcctttgc cttgacaggc ttggttgctg aaaaagattt
     7441 ccaaacagca gcagttccag ttgatttctt ctatgctaag ggaatccttg aagccctatt
     7501 tactcgtttg ggactccaag taacctatac agcaacatct gaaatcgtta gccttcatcc
     7561 aggtcgtaca gccgtgattt cactcggtga ccaagttctt ggtttccttg gccaagtgca
     7621 tccagtcact gccaaggctt acgatattcc agaaacgtat gtagctgagc ttaacctttc
     7681 agccatcgaa ggggcgctcc aacctgctgt tccatttgtg gaaatcacca aattcccagc
     7741 agtcagccgt gacgttgccc ttctcctcaa ggcagaagtg actcaccaag aagttgtaga
     7801 tgctatccaa gctgccggcg tgaaacgttt gacagatatc aaactctttg acgtcttctc
     7861 aggtgaaaaa ctgggacttg gtatgaagtc aatggcttat agcttgacct tccaaaatcc
     7921 agaagacagc ttaacggacg aagaagtcgc acgctatatg gaaaaaatcc aagcgtctct
     7981 cgaagaaaaa gtcaatgcag aagtgcgtta aacgatagta ggatacaaat tccccctcta
     8041 gtttatgaac attagagggg tgattttata taaaataatt aaaatgtgat ttctgtaaaa
     8101 atacatctat gatcagagtt ttgaaaactt acaatgtcta aatctttaac atagtagtgg
     8161 tttttaggca ataaaatatg atctattgtt gcattaaaaa gttttggact ttggctattc
     8221 caagttcctc tttcaaaagg tggcagtgca tttaatgcgt ccctatgaga gcttattttt
     8281 gcaagtgctc catgacgcat agttgcatta aaatcacctg caataatagc ctttggatat
     8341 tttgaagcca attgattatg aatgatgttt aagtcttgct tccagatttc cattaaacct
     8401 ggcagaggag gagcagtatg caaggcaatg atatctggta tattttgttt tctcgaatgt
     8461 aatacaattg tcccgaaccg tgttgtatga aaagttttag cttctgtata gaaaccataa
     8521 cttttcttga caatcacagt cacaggagct attccactat tggtaggtgg agaagtgaaa
     8581 atatcatagt tggccataga aagtccaact tgatgaaaca atagtttgat tctctggttt
     8641 tcttgctcac ctctgatatt ggtagctagt tcagggaata tagccatatc ggcgtcaaaa
     8701 tggctaaaaa ttcgctcaat atgttgtgct tctatttgat tagcgacgtt ccaagttact
     8761 aattttaagg ttttagtctt atttgatgca gaagaaaggg ttttatctgt tccgaataat
     8821 agtaatatga gcgatagtaa gagcaaaatg ccagagtaaa accgtatttg tttatttttc
     8881 ttgtaaaaag ataggaaaaa aaataagaaa cttaaaatag cagccatagt tgcagtagct
     8941 aaggggaagg cataaatctg tgccaagata ggttgggtag atagccaaat gttaagatta
     9001 gaagatggga aaaaagaata agttatgata gggatagaaa agagaatgac cgaaagggca
     9061 gagagaaatg ttttaatcat tgtgtgagta cctcaatttg caatggttgc tcggagctaa
     9121 tgtgactttg tgactttact tgattgatat tctttttctt gtcttcctca tagattaagt
     9181 acaacccaag taaaaaaagt ccaatttaag attgaaatga ttaaaaggca cagaaatgca
     9241 agacaattat actacaaaag gcaaacattt gacaatcgat agccgtcgct taatcgaacg
     9301 atggaaaaaa gaaggaaaat caaatagaga aattgcctct ctacttggaa aagctcctca
     9361 aactatccac actgaaatca agcgtgggac agtccgacaa tgtcttggaa aagggcgctt
     9421 caaagagatt tattctgccg actacgctca acagtcttaa gaaactaaag gaaaagattc
     9481 tccactatac ataaccaaaa acataaccaa aaattttcgc ctgaaatgat ggtgatggct
     9541 aaaggggtta acgtgggaat ttcaaccatt tactattgga ttcatcgtgg aaaattgggg
     9601 ttaagcaagc aggaactgct ttatcctaga aaaggaaaat cgcttaagaa ataggctagc
     9661 accaacttta aacccactgg tcaatctatc gaatcataat tcgctcattt ttttaaaaat
     9721 acatagacgt aaaaaaaaga gggttaagtg atgaagaata gtgctattgg gagtaattgg
     9781 aaggatgtcc atctgagctc tttagcaagg aggaaatcct tgaaagtgat atgcgagtgg
     9841 ctatcatgag cgagttgatt gaggctaggt atgaacaagg aatcagtcag aaaaagctgg
     9901 aagaagtcag tggaataagc cagcctgtca tagctaggat ggagacagga aagactagtc
     9961 ctcagttgga tacagtctta aaagtcctag ccagtttagg aaagacacta gcaatcgtcc
    10021 cacttgaaca gggaaaaagt tgactagaat cagttatagt cttttctaat aacaggtcat
    10081 agtcacttat aagaattact aataacatgt tttagtattc taattggaat atagctgtaa
    10141 agtaagaatt acaaaggatt tgagacgttt gcttcaagtc tttttctttt gtccgaaaca
    10201 gatatatagt ttcaaactat atcaaaccct aattttttac aattatacag acgctttctt
    10261 ttctgttaag atagtttcaa caacaaattt tggaggacac atcatgtcaa ctacaatcat
    10321 cggtttccct cgtttgggcg aattccgtga attaaaattt acaactgaaa aatactttag
    10381 aaaagaaatc tcagaagaag aacttttagc agcagcaaaa gacttgcgtg ctaaacactg
    10441 gaacattgtc aaagaaaaag gcatcactga aattccatca aatgactttt ctcactatga
    10501 taacttccta gatgcggctt tccttttcaa cgtggtgcct gcatccgttc aaaacttgga
    10561 cttgtctgac cttgagcgct acttcgcttt gggacgtggt taccagggag aaaaagggga
    10621 cgttcgcgcc cttccaatga agaaatggtt caacactaac taccactaca tcgttcctaa
    10681 atttgaaaaa gacactcaag taaaattggc tggtcacaag attttcgatg agttccaaga
    10741 agccaaagaa cttggattga acactcgtcc tgttcttgta ggtcccttca ctttccttca
    10801 attgtcagac tttgaagaag gcgtgaaagc agacgacttc gtagatagct tagtggctgc
    10861 ttaccaagaa gtttttgcta aattggctga acttggtgcg actcgcatcc aattggatga
    10921 agcggctctt gtaaaagact tgacagctga agaaaaagct ctcttcttga acctttacaa
    10981 caaactcttg gctgacaaaa aaggtcttga agtcttgctt caaacttatt tcggtgatgt
    11041 tcgtgacgta tacgctgacc ttgtaaactt accagtagat gctatcggtc ttgactttgt
    11101 tgaaggtaag aaaactcttg aactcgttaa aggtggcttc ccagctgaca agactctcta
    11161 tgtaggtatt gtcaatggta aaaacatctg gcgcaacaac tacgaaaaga gcttggctgt
    11221 tcttgagcaa attccagctg aaaacatcgt tttgacaagc tcttgctcac ttcttcatgt
    11281 gccatttaca actgctaatg aagaatttga accagcactc ttgaaccact ttgcctttgc
    11341 agttgaaaaa ttggatgaaa tccgtgactt ggatgctatc cgaaatggtc aaggttcaga
    11401 agctcttgca gccaacaaag aactctttgc gactgagcgt gttggtgaaa atgctgaact
    11461 tcgtgcgcgt atcgctggct tgacagacgc agactacact cgtttgccag cctttgcaga
    11521 acgtgaagct atccaagaag aagctttcaa acttccagct cttccaacaa caacgattgg
    11581 ttcattccct caaacaaaag aagttcgtgc caaacgtttg gcttaccgta aaggtgaatt
    11641 gtctcaaaaa gagtacgacg ctttccttgc tgaaacgatt gacgaatgga tcaagtggca
    11701 agaagatatt gactttgatg tccttgttca cggtgaattt gagcgtaatg acatggttga
    11761 gtacttcggt caaaacttgt caggatacct cttctctaaa aatggatggg tacaatcata
    11821 cggtatgcgt ggggtaaaac caccaatcat ctggggtgat gtcactcgtc ttaaccctat
    11881 cactgttaaa tggtctagct atgcacaaag tcgtacaaac aaacctgtta aaggtatgtt
    11941 gactggacct gttaccatcc ttaactggtc attcccacgt gaagacatct ctatcaagga
    12001 ttcaactctc caaatcgccc ttgctatcaa ggatgaagta cttgaccttg aagctgctgg
    12061 tgtgaaaatc atccaaatcg acgaggctgc tcttcgtgaa aaattgccac tccgccgtag
    12121 cgactggtac gaagactacc ttgactgggc tattcctgcc ttccgcttgg tacactcaac
    12181 agtagcgcca gacacacaaa tccacactca catgtgttac tcagaattta cagatatcat
    12241 cccagctatc gataacatgg atgcagacgt tatttccttt gaagctaacc gttcaaacct
    12301 tgaaatcttg gacgaactca aagcgaaaaa cttccaaaca gaagtgggac ctggggttta
    12361 cgatatccac tcacctcgtg taccaaatga aggcgaaatc gacaacacaa tcgaagccat
    12421 ccttgctaaa gtgccaagca agaaagtttg gatcaaccct gactgtggtt tgaaaacacg
    12481 tggtatccca gaaacaaaag aaagcttgat ccgccttgtt gaagcagcta aagctgcgcg
    12541 tgagaaattg taagattgga tttctctcca tacagtggtt gttcaaaaag aaatcaacta
    12601 gaaaaggtta ttacatatgt cacgccaaac accgtcactc tcatttgaag tgttccctcc
    12661 aaacccagcc gtgggtaatg ataacattat ttcagccttg caggatatgc aggagttggc
    12721 tccccatttt atcagtgtaa ctgccagcaa taataaattt aatatcaagg aaacgacggt
    12781 tcgtttggct gactttatcc aaaatgattt ggcgattccg accattgccc acttgccagc
    12841 tatttatcta actaaggaca aggttgctga aactattgct gacttggaca aagttggggt
    12901 gcagaaaatc ttggctcttc gtggggatat tattccagac gtggaaccac aaaaggattt
    12961 ccgctatgca accgacttga ttgagtttat caaggaacaa acccctcact ttgatattat
    13021 tggagcttgc tatccagaag ggcatccaga ttcgccaaat cagatttcag atattcaaaa
    13081 tcttaagaag aaagtggatg caggctgttc gagcctcgta actcagctct tctttgacaa
    13141 tgagcgcttc tatgattttc aggacaagtg tatcttggct gggattgatg ttcccattca
    13201 tgcaggaatt atgccaattc tgaatcgaaa tcaggctctc cgactcttga agacttgtga
    13261 gaatatccat cttccacgca aatttaaagc catcttagac aagtatgagc atgaccctga
    13321 gtcgctcaga gcagcaggac ttgcctatgc agtggaccaa atcgtggact tggtaactca
    13381 ggatgttgcc ggtgtgcatc tctatacgat gaataatgct gatacagcaa aatacatcca
    13441 tcaagcaacc catgccttgt ttaatcacca gtctctagga taataaaagc aaaccattct
    13501 tctcaggtga ggggaatggt tcctttttaa tggtaaagac ctcacttttt aagaaaaata
    13561 tgataaaata aattctgtac gtacttgata caaagatgaa ggtattaaat aatacaatgc
    13621 atttaaactg taagatttaa cgacacgagt gagtcaaatc gatgttattt gacgagagag
    13681 ttagtaaagc atttagctaa tcgcccgata gcgattagcg tgaaagcttt agatacttta
    13741 gtattaaacc tttctaatga tgtatcttga aaactgaact tgcctacaac tctgtggaaa
    13801 aagataaatc tccctaggag tagtcgctcc gtcgttcgat ttcctatctt cctttgagtt
    13861 gcttgacggc ttggtatctt gatgacttga attttggtct catttcttag gaaaaaagat
    13921 aagcttccta gcactcgtcg agtgcgacgt caccttccta tttttctaca gaaatgttcg
    13981 gcaagccgaa ccgtccaaaa tatcttgtgt aattgaacac ggccgaaaag ctgtgtaaaa
    14041 aagataaact gtcttgtctt catcgaagac ttcgtcagtt tcctattttt actttgcttt
    14101 tgacgtcctt ggtatcttga tctttgtagg caaggcgtat aatttcatca atccaaaggg
    14161 gattaaaatg gcaaaacaag tgtttcaaac gacttttgcg ggtcgtgagt taattgtaga
    14221 gactggtcag gttgctaagc aagcaaatgg atctgttgtc gtacgttacg gtgagtcaac
    14281 tgtcttgact gctgccgtta tgtctaagaa aatggcaact ggggatttct tcccactcca
    14341 agtcaactac gaagaaaaaa tgtatgcggc tgggaagttt cctggtggct ttatgaaacg
    14401 tgaaggacgt ccttcaacag atgcgacctt gacagcgcgt ttgattgacc gtccgattcg
    14461 tcctatgttt gcggaaggtt tccgtaatga agtccaagtc atcaatacag tgctttctta
    14521 tgatgaaaat gcatctgcac caatggctgc tatgtttggt tcatctttgg cactgtctat
    14581 ttcagatatt ccatttgacg gaccaattgc tggggtacaa gtgggatatg tagatggcca
    14641 aatcatcatc aacccaagtc aagaacaagc agagcaatct cttcttgaat tgacagtagc
    14701 tggaaccaag cacgctatca acatggtaga gtctggtgcc aaagaattgt cagaagaaat
    14761 catgttggaa gcgcttctta aagggcacga agctgtcaaa gaattgattg ccttccaaga
    14821 agaaatcgtt gctgctgtcg gtaaagaaaa agcagaagtg gaattgcttc acgtggatgc
    14881 tgaattgcaa gctgaaatca ttgcagccta caacagtgac ctccaaaagg cagttcaagt
    14941 agaagagaaa ttggcacgtg aagctgcgac tcaagtagtg aaagaccaag tgactgccgt
    15001 ttacgaagaa aaatatgcgg accacgaaga atttgaccgt attatgcgtg atgtggctga
    15061 aattttggaa caaatggaac acgcagaagt gcgacgttta attacagaag acaaggtgcg
    15121 tcctgatggt cgtaaggtcg atgaaatccg tcctttggat gcggttgttg acttccttcc
    15181 tcgtgtacat ggttcaggtc tctttactcg tgggcaaact caagctcttt cagtcttgac
    15241 cttggctccg atgggagaaa ctcaaatcat tgatggtttg gatccagagt acaagaaacg
    15301 ctttatgcac cactataact tccctcaata ttctgtaggg gaaacaggtc gttacggtgc
    15361 gccaggtcgt cgtgaaatcg gtcacggtgc tcttggtgag cgtgctcttg ctcaagtctt
    15421 gccaagcttg gaagaattcc catacgctat ccgtctagta gcagaagttt tggaatcaaa
    15481 cggttcttca tctcaagctt ctatctgtgc gggaactctt gcccttatgg ctggtggtgt
    15541 gccaatcaag gcgccagtag ctggtattgc tatgggactt atctcagatg gaaataacta
    15601 cacagtattg acagatatcc aaggtttgga agatcacttt ggagatatgg acttcaaggt
    15661 tgcaggtact cgtgatggga ttacagccct tcaaatggat atcaagattc aagggattac
    15721 tgcagaaatc ttgacggagg ctcttgctca agccaagaaa gcgcgttttg aaatccttga
    15781 tgtcattgaa gcaaccattc cagaagttcg tccagaattg gctccaactg ctccgaaaat
    15841 tgatacgatc aagattgatg tggacaagat taagattgtc atcggtaagg gtggagaaac
    15901 catcgacaag attatcgctg aaacaggtgt taagattgat atagacgaag aaggaaatgt
    15961 gtctatctac tctagtgacc aagatgctat taaccgtgcc aaagaaatta ttgctggttt
    16021 ggttcgtgaa gccaaagtgg atgaagttta ccgtgctaaa gtcgttcgta tcgagaaatt
    16081 tggtgccttt gttaacctct ttgataagac agatgccctt gttcatatct ctgagatggc
    16141 ttggactcgt accaatcgtg tagaggattt ggtagaaatc ggggatgaag ttgatgttaa
    16201 ggttatcaaa attgatgaaa aaggccgtat cgatgcctct atgaaggctc ttctacctcg
    16261 tccgccaaaa cctgagcatg atgaaaaagg tgaaaagtct gagcgccctc accgcccacg
    16321 tcatcacaag gatcacaaac ctaagaaaga atttacagaa acaccaaaag attcagagta
    16381 agaaaaggag aaatgtatgg ggtggtggcg cgaaaccatt gatatcgtaa aagaaaatga
    16441 tccagcggcc cgcaccactt tggaggtttt gctgacttat ccaggtgtca aggccttggc
    16501 ggcccaccgt ctctcgcatt ttctctggaa gcacggcttc aaactcttag ctcgtatgca
    16561 cagtcagttt tggcgctttt ggactcagat tgagattcat ccaggagccc agattgattc
    16621 aggtgtcttt attgaccatg gttctggtct ggtgattgga gagacagcga ttgttgaaaa
    16681 aggcgttctt ctctatcacg gagtgactct tgggggaaca gggaaagact gtggcaaacg
    16741 ccatccgact gtacgaaagg gagccctcat atcagcccat gcccaagtta tcgggcctgt
    16801 ggaaattggt gaaaatgcca aggtcggtgc tgcagcagtt gtcgtagcag atgtacctag
    16861 tgatgtgacg gttgtcggta ttccggccaa gattgtccgt cttcatggta agaaagatga
    16921 gcctgtcatt cacgaagtcg aagaaaaacg agagtattat gtcaataaac tcgagcaggc
    16981 taaagatgcc agtcacagat cgtctggttt gtagaggata cctatatgat tcaagcaaga
    17041 aacaagttaa gccaagagga gctatctgag gcgaaaaaag taattaactg ttgccaaaac
    17101 tatgacggta cctatcgcga tccctatctc tctaacatgc ttaattttga cccaaacatg
    17161 cccgcctttt tcctttatta tgaaaaaggc gaacttgttg gtttattaac tgtctatgca
    17221 gatgaccaag atgtagaagt aacgatactg gttcatccag gtcatcgccg tcaggggatt
    17281 gcgcgtgcat tgtttactag ttttgagaga gaaacagctt ctttccccat tcggtcagtc
    17341 acttttcaga cagaacgtat ttttttagag aatcatcctg actttgccag taactgggga
    17401 ctaatcgagg atgaagagac agaaacttgg ttaggtaagg atagaagacc ttatccgtta
    17461 gcaaatgttt cccatcttga agttttgtta gcagatagtt cgtatcagga tcaaattagt
    17521 caattaaaat ttcaggcatt ttcagaggaa catgaatcga gagaagttgt ggatagatat
    17581 gtcgctgaag ctctgaagga tccagaaagt cgcttatata ttttgttaaa agacggtcag
    17641 gttattggga cttgcacggt agatttatcg actaatacga attacttcta cggtttagca
    17701 atatcggaac ctgaacgtgg gaaaggctat ggaagctact tagcaaaatc cctcgtcaac
    17761 caactaattg agcaaaatga caaggaattt cagattgcag tggaagatag caatgtaggt
    17821 gccaaacgtt tgtatgaaaa aattggcttt gtcaaacaga ctcaggtggt ttatttgaat
    17881 gagaaaggag taagggattc cgaagtgtag agacattcgg actgaaattt acttgagctc
    17941 ttagtttagt gatgcaacta acagttcttg gattttagct ttcctgatta tgatttatga
    18001 ttaaaatcta tgacaccatg tctcgtgatt tgcgagaatt tgtcccaatt gagaacggta
    18061 aggttaagat gtatgtctgt gggccaaccg tgtacaacta tattcatgta gggaatgctc
    18121 gttcgacggt agcttttgat acgattcgtc gctattttga gtaccgtggg tataaggttg
    18181 cctatatttc caattttaca gatgtggatg ataagattat caaccgtgcc agggaagaag
    18241 gtatcacgcc tcaggaggtt gcggataagt acatcgctgc ctttcgtgag gatgtgacgg
    18301 ccttaggcgt gaaacctgcg actcgccatc cgcgtgtagt ggagtttatg gcagacatca
    18361 tccgttttgt ggaagacttg atcgagaaag gctttgccta tgagagtcaa ggggatgtct
    18421 atttccgtgt agaaaaatcc cacaactatg ctaaattggc taataaaact ttggaagatt
    18481 tggatctagg tgcttcaggt cgtaccgatg aagaaacggc tcgtaaggaa aatcctgtag
    18541 attttgctct atggaaatct tccaaaccag gtgagatttc ttgggatagt ccttggggac
    18601 ctggacgtcc gggttggcat attgagtgtt cagtcatgtc gacagagatt ttaggtgata
    18661 ccattgatat ccacggtggt ggagctgacc tagagtttcc acaccacacc aatgaaattg
    18721 cccagtctga agctaaaaca ggcaaggctt ttgctaacta ctggatgcac aatggctttg
    18781 tcaatatcga caatgtcaaa atgtctaagt ccttgggtaa cttcattacg gtacacgatg
    18841 cccttaaaac tcttgatggg caagtacttc gtttcttctt tgcgacccag cactaccgta
    18901 agcctatcaa cttcacggaa aaggcagttc gcgatgccga gaccaatctc aagtatctga
    18961 agaatactta cgaacaacca tttacaggaa atgtggatgc ccaagagtta caaaacttta
    19021 aagataagtt tgtagcagct atggatgaag attttaatgc tgccaacggt atcacagttg
    19081 tctttgaaat ggccaaatgg atcaactcag ggaactatga tgcaagtgtc aagcaagctc
    19141 ttgcagatat gttagaaatt tttggaattg tctttgttga ggaagttttg gatgcagaga
    19201 ttgaagactt gattcaaaaa cgccaagagg cgcgtgccaa tcgtgacttt gcgacagcag
    19261 accaaatccg tgaccaattg gttactcaag gaattaagct ccttgatacc aaggatggag
    19321 tgaggtggac acgtgattga tgtcaatctc attaacggga ttgcgctagc ctttgagggg
    19381 gatgcggtgt attctatgta tattcgccgt cacctcatcc tcaaaggtat gaccaaaccc
    19441 aataaactcc atcaagaagc aactaagtac gtgtcagcca aggctcaggc tcgcctgatt
    19501 gctctcatgt tggaggagca ggtcctaacg gaaaaagaag aagaaatcta caaacgtggc
    19561 cgcaatacca atagccacac aaaggctaaa aatgcagatg tcgtgactta tcgtatgtcc
    19621 acgggatttg aagcggttat gggctatctc catatgactg agaatctgga acgtcttgag
    19681 agtttggttt catggtgcat ccaaaaagtg gagggctaga acatgagggc aaaagaacta
    19741 caagactggt ttcctgaggc tcggatttca gaccaaccag tagagaaaga gggctatctc
    19801 acgctccctt tagcttctca gcagtggatt ttgctggagg aagctgggct cagcgagcgt
    19861 gaaaagcagt tggttgccct tttgacccag caggagcagg ctcgttcgct aaacccttgg
    19921 tattcctatc tggttgaggg caagggacag gcaccgcaag tttttaaaaa gattcagttg
    19981 gtttattgcc atctttctta ttttcagcag gaaaatctgg cttcttggct agatatgatg
    20041 cggactcttt ttccgaattg tcagacagtg ctacaggtcg gagctcagga ttatgttttc
    20101 gtgcttcaac aagacaaata cacttctgta agagatattt taagtgatac gattgaagcg
    20161 gttgagtatg actttggact tcgtctttct atcatgttgg gtcaggtttg gtctcagacg
    20221 ggacatcaag ccctatcaga cttaatcaaa gctgagcggg atttgttcaa gacatggtgg
    20281 cgtcagggtc accaaggtgt tcatactttt tctcagctct atctttggag tatgggagaa
    20341 agactcgtgg acttgaagcc aatcaaggaa tgtctacacc agatgatttt ggatcaagat
    20401 cagattcagg aaatcattct ctctctttgg gaaaatagtg ctgttctcac taaaacagcc
    20461 cagcaactct atctgcaccg caattctctc caatacaaga ttgataaatg ggaagagttg
    20521 acagggcttc agttgaaaga gttgaccgac ctgaccttgt gttatcaatt gattttaggt
    20581 tctttgtcaa ctatagttgg tttgtaaaga agttaatatg gctctttgtc aactgtagtg
    20641 ggttgaaaaa aagctaagct cgagaaagga caaattttgt cctttctttt ttgatattca
    20701 gagcgataaa aatccgtttt ttgaagtttt caaagtttcg aaaaccaaag gcattgcgtt
    20761 tgataagttt gatgagatta ttggtcgctt ccaatttggc gtttgaatag ggtagttgaa
    20821 gggcgttgac gattttctct ttgttcttta gaaaggtttt aaagacagtc tgaaaaatag
    20881 gatgaacctg cttcagattg tcctcaatga gtccgaaaaa tttctcaggg tctttgttct
    20941 gaaagtgaaa aagtaagagt tgatagatct gatagtggtg tttcaagtct tctgaatagc
    21001 ttaaaatctt gtcaagaatt tctttatttg ttaagtgcat gcgaaaagta gggcgataaa
    21061 aacgtttatc gctgagttta cgactatcct gttggatgag tttccagtaa cgcttgatag
    21121 ccttgtattc atgagatttt cgttcaaact gattcataat t
//
LOCUS       DAVLTT010000032        20825 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLTT010000032 DAVLTT010000000
VERSION     DAVLTT010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20825
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.032"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(187..274)
                     /locus_tag="VYN15_001303"
     tRNA            complement(187..274)
                     /locus_tag="VYN15_001303"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(238..240),aa:Ser,seq:gga)
     gene            437..1177
                     /locus_tag="VYN15_001304"
     CDS             437..1177
                     /locus_tag="VYN15_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1452617.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            1174..2085
                     /gene="pfkB"
                     /locus_tag="VYN15_001305"
     CDS             1174..2085
                     /gene="pfkB"
                     /locus_tag="VYN15_001305"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV1452618.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSDGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            2082..4034
                     /locus_tag="VYN15_001306"
     CDS             2082..4034
                     /locus_tag="VYN15_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1452619.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAAMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLAISGDAEVYRAANGAK
                     VATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVACSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGSLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            4198..6423
                     /locus_tag="VYN15_001307"
     CDS             4198..6423
                     /locus_tag="VYN15_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1452620.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALKYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(6467..6895)
                     /locus_tag="VYN15_001308"
     CDS             complement(6467..6895)
                     /locus_tag="VYN15_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452621.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSPNKENKTSQEKTQQEETPKSSVKE
                     EKKEEQKTATQDSTTPATSKPATENEKQPNTPTSENKSNQ"
     gene            7058..9142
                     /locus_tag="VYN15_001309"
     CDS             7058..9142
                     /locus_tag="VYN15_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1452622.1"
                     /translation="MFEIRNLSLSFAGRRLLEPTDLIFERGKVYTIYGKSGVGKSSLL
                     NKIGLLSATDPSVSYFFDGKEIDIENKKSVSVFIAEEVAFVFQGRNLINDLTVFENLR
                     LALNFYDLSPDEIESKIDTVLADLQISSLKHAYPEDLSGGEEQRVAIARALVTGKTLI
                     LADEPTSSLDKENREKVSALLIDLAHKYHKIVLIVSHDEAMIAIGDVQLHFKDHKLVG
                     NCLILNSDEGIKDSKKWSSCLSSSHTKLSVLKHRRPFLPRLLAFFISLVVAIAVTSIN
                     FQSLFADKYHQLVNNSLENGFLVINDSLHLQTTKVLDDFLSFDKEEITSISTSQNIQT
                     VNPYIEFLSLGMTFDNSKDYSQLQKNFQPTLTIDGQTRSLTRNFSIQPLYQTNTTQRQ
                     IEYFDRSNEKGIYLSEQFISDEKLPNIVSGTTVTLTFYIPISLYESSIEKEGNILKGD
                     GDLFVKVDKTYPVLGIVKKSYPFEYSPYGNTLFMNIAEMEELQNEAIQQHPMTKMALD
                     GFPLKSWMPSAIHVLLKDSGAIPEELSRIRAISSQITILSSYENYEEFNKGLTYIRQF
                     LMLLSLVLLILVIAVLSFVFFLLNRPRRFEVGILKSLGYSTQNIVWLFLKELIGYGKT
                     ISILASCLLVILSILAMQVLKLEISDVFKFYLTSVFTLIGLSVSVLIISGLLPIYTTC
                     RQTVVDTIRKNG"
     gene            9152..9529
                     /locus_tag="VYN15_001310"
     CDS             9152..9529
                     /locus_tag="VYN15_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452623.1"
                     /translation="MKHKIMKKIIVVVFAIPWLTFLSQVHADYVSKSSSLDGYSLVGL
                     NVLNVTFNASGYSDTYSGSVSNMYFTDWAWFPNTISNRSTWKSSIPYGQRANGTVHIG
                     VGVNSPWGAVNLWGGQNYFSLDF"
     gene            9689..10831
                     /locus_tag="VYN15_001311"
     CDS             9689..10831
                     /locus_tag="VYN15_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1452624.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLVGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            10840..12054
                     /gene="thiI"
                     /locus_tag="VYN15_001312"
     CDS             10840..12054
                     /gene="thiI"
                     /locus_tag="VYN15_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV1452625.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            12189..13013
                     /locus_tag="VYN15_001313"
     CDS             12189..13013
                     /locus_tag="VYN15_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1452626.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            13035..13370
                     /locus_tag="VYN15_001314"
     CDS             13035..13370
                     /locus_tag="VYN15_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEV1452627.1"
                     /translation="MHIEHLSHWSGHPNREMYLNRYGHGGIPVVVFASSGGSHNEYYD
                     FGMIDACASFIEEGLVQFFTLSSLDSESWLATWKNAHDQAEMHRAYERYVIEEAILLS
                     STRQVSLMA"
     gene            13367..13774
                     /locus_tag="VYN15_001315"
     CDS             13367..13774
                     /locus_tag="VYN15_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1452628.1"
                     /translation="MMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFVGDYY
                     NDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCTGLGAWEQDGLPSFYKLKEAFDQK
                     QIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            13787..14953
                     /locus_tag="VYN15_001316"
     CDS             13787..14953
                     /locus_tag="VYN15_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1452629.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            15461..16954
                     /locus_tag="VYN15_001317"
     CDS             15461..16954
                     /locus_tag="VYN15_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1452630.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            16967..18088
                     /locus_tag="VYN15_001318"
     CDS             16967..18088
                     /locus_tag="VYN15_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1452631.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLA
                     LQNEFADFVAQVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            18148..18384
                     /locus_tag="VYN15_001319"
     CDS             18148..18384
                     /locus_tag="VYN15_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV1452632.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            18381..18794
                     /locus_tag="VYN15_001320"
     CDS             18381..18794
                     /locus_tag="VYN15_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV1452633.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            18912..19877
                     /locus_tag="VYN15_001321"
     CDS             18912..19877
                     /locus_tag="VYN15_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1452634.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKVNLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            19911..>20825
                     /locus_tag="VYN15_001322"
     CDS             19911..>20825
                     /locus_tag="VYN15_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1452635.1"
                     /translation="MKKVKLGEVATFINGYAFKPQDWSSEGREIIRIQNLTKTSTEIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIYG
                     SGGIMGYAKDWIVKKNSVIIGRKGNINKPILVRENFWNVDTAFGLEPVLEKINSEYLF
                     YFCQLYNFEKLNKAVTIPSLTKSDLLNIS"
BASE COUNT         6542 a         3629 c         4459 g         6195 t
ORIGIN      
        1 tttgagattt tgtcttttac tgttcgtaaa atcgtatgag ataagaaggg agtggaaaga
       61 attcatactc tctctagaac ttgtatattg aaacgatgtg gagattgtaa agaaattaca
      121 aaatacccca aaactaagat agaaatacaa agtttcaggg tatcatatat tttatctgtt
      181 tttcgacgga agacatggga ttcgaaccca cgcacgctat tacacgccta ccgcgtttcc
      241 aacacggcct cttaagcctc ttgagtaatc ttccaatact tactcaaata gtctaccata
      301 aaggctctta tcttgcaata aaaattctag aaataagaaa aaatgataga ttttgaaaga
      361 aaatgataaa aaatgcttga cttcgaaaga aagtatgata gaatgaatag tgtaaacgat
      421 aacaggaggt gattcagtgt taaaaacaga acgtaaacaa ctaattttag aggagttaaa
      481 tcaacatcat gtagtttctc tagaaaaatt agttagtttg ctagaaacgt cagaatcaac
      541 ggttcgaaga gacttggatg agttggaagc ggaaaacaag cttcgtcgtg tgcatggtgg
      601 agcagaactc ccccactcct tacaggaaga agaaaccatt caagaaaaat ctgtcaaaaa
      661 ccttcaagaa aagaagttgc tggctcagaa agcagcctct ctcattaaag aaaaagatgt
      721 catctttatc gatgctggaa caacaactgc ttttttgatt catgaattgg tcaataagaa
      781 tgttacagtt gtgaccaact ccattcacca tgccgctcag ttggttgaaa agcagattcc
      841 aactgtcatg gttggaggaa acgtcaagac ggcgacagat gctagtatcg ggggcgttgc
      901 tcttaaccag attaaccaat tgcactttga ccgtgccttt atcggaatga atggtgttga
      961 cgatggctat tatacgactc ctgatatgga ggagggagct gtgaaaagag ctattttgga
     1021 gaatgccaag cagacctacg tcttggtgga ttcgtcaaaa attggacaaa cttgctttgc
     1081 caaggtagca ccactcaaac gcgctatcgt tatcactagt caagggcatg agctcttgca
     1141 ggttattaag gagaaaacgg aggtaataga agtatgattt atacagtcac actcaatcca
     1201 tccattgact atatcgttcg tttggaccaa gtcaaagttg gtagtgtaaa tcgtatggac
     1261 agtgatgata agtttgctgg tgggaaagga atcaatgtca gccgtgtctt gaaacgtttg
     1321 aatataccaa atacagcgac gggatttatc ggtggcttta ctggtaaatt tatcacagat
     1381 actttagcag aggaagaaat cgagacacgt tttgtccagg tggcagaaga tactcgtatc
     1441 aatgttaaaa tcaaagcaga ccaagaaaca gaaatcaacg gaacgggtcc aactgttgaa
     1501 tcggttcagc tagaagaatt gaaagctatt ttatctagtc tgacagcaga agatacagtt
     1561 gtctttgcag gttcaagtgc taaaaatcta ggcaatgtta tctataagga tttgatttcc
     1621 ttgacgcgcc agactggtgc gcaagtggtc tgtgactttg aaggacagac cttaattgat
     1681 agtttggact accagcctct tcttgtaaaa ccaaacaatc atgaacttgg agcgattttt
     1741 ggggttaaac tcgaaagttt agatgaaatt gagaaatacg ctcgtgagtt actggctaag
     1801 ggtgctcaaa atgttattat ctctatggct ggtgatggtg cccttcttgt cacatctgat
     1861 ggagcttact tcgctaaacc aatcaaggga acagtcaaaa attcagttgg agctggtgat
     1921 tctatggttg ctggattcac aggtgaattt gtcaaatcaa aagacgcagt agaagccttc
     1981 aaatggggag tggcttgcgg aacggcaact accttctcag atgacttggc aacggcggaa
     2041 tttattaaag aaacatatgg aaaagttgag gtagaaaaac gatgaaaatt caagacctat
     2101 tgagaaaaga tgtcatgttg ctggatttgc aggcaactga aaaaacagct gtcatcgacg
     2161 agatgattaa aaatttgaca gaccacggtt atgtaacaga ttttgaaaca tttaaagaag
     2221 gaattttggc gcgtgaagct ttgacttcta ctggtttggg tgatggaatc gcaatgcctc
     2281 acagcaaaaa cgctgctgtc aaagaagcga cagttctatt tgctaagtca aataagggtg
     2341 ttgactacga gagcttggat ggacaagcaa ctgacctctt cttcatgatt gcagctccag
     2401 aaggtgccaa tgatactcac ttggcagcct tggcagaatt gtctcaatac ttgatgaaag
     2461 acggttttgc agacaaactt cgtcaagcaa catctgcaga ccaagttatc gaactttttg
     2521 accaagcttc agaaaaaact gaggaacttg ttcaagcacc tgctaatgac tctggtgact
     2581 ttatcgtagc tgttacagct tgtacaacag gtattgccca cacttacatg gcccaagaag
     2641 cccttcaaaa agtagctgct gcaatggggg ttggtatcaa ggtcgaaacc aacggtgcta
     2701 gcggtgttgg aaatcaacta actgcagaag atatccgtaa ggctaaagct attatcattg
     2761 cagcagacaa ggccgttgaa atggatcgtt tcgatggcaa acctttgatc aatcgtccag
     2821 ttgctgacgg tatccgtaag acagaagaat tgatcaactt ggctatttca ggagatgcgg
     2881 aagtctaccg tgccgctaat ggtgccaaag tcgcaacagc ctctaacgaa aaacaaagcc
     2941 ttggtggtgc cttctacaaa cacttgatga gtggtgtatc tcaaatgtta ccattcgtta
     3001 tcggtggtgg tatcatgatt gcccttgcct tcttgattga cggtgctttg ggtgttccaa
     3061 atgaaaacct tggcaatctt ggttcttacc atgagttagc ttctatgttc atgaaaattg
     3121 gtggagctgc ctttggtttg atgcttccag tctttgcggg ttatgttgcc tgctctattg
     3181 ctgaaaaacc gggtttggta gcaggtttcg tggctggtgc tattgccaaa gaaggttttg
     3241 cctttggtaa aattccttat gccgcaggtg gtgaagcaac ttcaactctt gcaggtgtct
     3301 catctggttt cctaggtgcc cttgttggtg gatttatcgc aggtgccttg gttcttgcca
     3361 tcaagaaata cgttaaagtt cctcgttcac tcgaaggtgc taaatcaatc cttctattgc
     3421 cacttcttgg aacaatcttg acaggatttg ttatgttagc tgtgaatatc ccaatggctg
     3481 caatcaacac tgctatgaat gacttcctag gcagtcttgg aggaggttca gctgtccttc
     3541 ttggtatcgt ccttggtgga atgatggctg ttgacatggg tggaccagtt aataaagcag
     3601 cttatgtctt tggtacaggt acgcttgcag caactgtttc ttcaggtggt tctgtagcca
     3661 tggcagcagt tatggctgga ggaatggtgc caccacttgc aatctttgtc gcaactcttc
     3721 ttttcaaaga taaatttact aaggaagaac gtaactctgg tttgacaaac atcatcatgg
     3781 gcttgtcatt tatcactgag ggagcgattc catttggtgc cgctgaccca gctcgtgcga
     3841 ttccaagctt catccttggt tcagcagtag caggtggact cgttggtctt actggtatca
     3901 aactcatggc gccacacgga ggaatcttcg ttatcgccct tacttcaaat gctctccttt
     3961 acctcgtttc tgtcttggta ggagcaatcg taagtggtgt ggtttatggt tacctacgca
     4021 aaccacaagc ataaaaaata gaaaaatgaa aagattggac cgtttggtgc agtctttttc
     4081 tcttcccgaa atgcctgtga aatatggtat aatagaagaa tggcaaacaa gaatacaagt
     4141 acaacaagac ggagaccgtc taaagcagaa ctggaaagaa aagaagcgat tcaacgaatg
     4201 ttgatttcgt taggaattgc gattttattg attttcgcag ccttcaaatt aggggctgca
     4261 ggtataaccc tttataattt aattcgcttg ctagtgggta gcctagctta tctggcgata
     4321 ttcggcctat taatctatct cttctttttc aagtggatac gaaaacagga aggactctta
     4381 tctggctttt tcaccatatt tgctggctta ctcttgattt ttgaggccta cttggtttgg
     4441 aaatatggtt tggacaagtc cgttctaaaa gggaccatgg ctcaggttgt gacagatctg
     4501 actggttttc gaacgactag ctttgctgga gggggcttga tcggggtcgc tctttatatt
     4561 ccaacagcct ttctcttttc aaatatcgga acttacttta ttggttctat cttgatttta
     4621 gtgggttctc tcctagtcag cccttggtct gtttacgata ttgctgaatt tttcagtaga
     4681 ggctttgcca aatggtggga agggcacgag cgtcgaaaag aggaacgctt tgtcaaacaa
     4741 gaagaaaaag ctcgccaaaa ggctgagaaa gaggctagat tagaacaaga agagactgaa
     4801 aaagccttac tcgatttgcc tcctgttgat atggaaacgg gtgaaattct gacagaggaa
     4861 gctgttcaaa atcttccacc tattccagaa gaaaagtggg tggaaccaga aatcatcctg
     4921 cctcaagctg aacttaaatt ccctgaacag gaagatgact cagatgacga agatgttcag
     4981 gtcgattttt cagccaaaga agcccttaaa tacaaacttc caagcttaca actctttgca
     5041 ccagataaac caaaagatca gtctaaagag aagaaaattg tcagagaaaa tatcaaaatc
     5101 ttagaagcaa cctttgctag ctttggtatt aaggtaacag ttgaacgggc cgaaattggg
     5161 ccatcagtga ccaagtatga agtcaagccg gctgttggtg taagggtcaa ccgcatttcc
     5221 aatctatcag atgacctcgc tctagccttg gctgccaaag atgtccggat tgaagcacca
     5281 atccctggga aatccctaat cggaattgaa gtgcccaact ccgatattgc cactgtatct
     5341 ttccgagaac tatgggaaca atcgcaaacg aaagcagaaa atttcttgga aattccttta
     5401 gggaaggctg ttaatggaac cgcaagagct tttgaccttt ctaaaatgcc ccacttgcta
     5461 gttgcaggtt caacgggttc agggaagtca gtagcagtta acggcattat tgctagcatt
     5521 ctcatgaagg cgagaccaga tcaagttaaa tttatgatgg tcgatcccaa gatggttgag
     5581 ttatctgttt acaatgatat tccccacctc ttgattccag tcgtgaccaa tccacgcaaa
     5641 gccagcaagg ctctgcaaaa ggttgtggat gaaatggaaa accgttatga actctttgcc
     5701 aaggtgggag ttcggaatat tgcaggtttt aatgccaagg tagaagagtt caattcccag
     5761 tctgagtaca agcaaattcc gctaccattc attgtcgtga ttgtggatga gttggctgac
     5821 ctcatgatgg tggccagcaa ggaagtggaa gatgctatca tccgtcttgg gcagaaggcg
     5881 cgtgctgcag gtatccacat gattcttgca actcagcgtc catctgttga tgtcatctct
     5941 ggtttgatta aggccaatgt tccatctcgt gtagcatttg cggtttcatc aggaacagac
     6001 tcccgtacga ttttggatga aaatggagca gaaaaacttc ttggtcgagg agacatgctc
     6061 tttaaaccga ttgatgaaaa tcatccagtt cgtctccaag gctcctttat ctcggatgac
     6121 gatgttgagc gcattgtgaa cttcatcaag actcaggcag atgcagacta cgatgagagt
     6181 tttgatccag gtgaggtttc tgaaaatgaa ggagaatttt cggatggaga tgctggtggt
     6241 gatccgcttt ttgaagaagc taagtctttg gttatcgaaa cacagaaagc cagtgcatcc
     6301 atgattcagc gtcgtttgtc agttggattt aaccgtgcga cccgtctcat ggaagagctt
     6361 gagatggcag gtgtcattgg tccagctgaa ggtaccaagc caagaaaagt attgcagcaa
     6421 taaaaaatag cttctttcca aggttggaag gaagctattt ttctggttat tgattacttt
     6481 tattttctga agttggagta ttgggctgtt tttcattttc agtggcaggt ttacttgtag
     6541 caggtgtagt agagtcctga gttgctgttt tctgctcttc ttttttctct tccttgacgc
     6601 tagattttgg cgtttcttct tgttgtgttt tttcttgaga agtcttattt tccttattgg
     6661 gactagtatt ttcctgaggg gattcctttt gaatttcttt gacaattgtt gtcgtctggc
     6721 ttgttgtagg ttccttttta gtatttttgt tattatccaa ggcgttcata atcgtgatac
     6781 tagcggtaat caagccaagg atactagcga tagtcgcaac ggttttttga aagactgtaa
     6841 agcctttttt gatgtgttct gtttttggtt ttgaagttct acgataatta gacatacatt
     6901 ctctccttta attaaaattt attatacctc atttctttaa aaaaatctta aaaaaagagg
     6961 agatttttct acacgaactt cagtaattag ttgaaataaa atatgactta tgatataaca
     7021 aaataaagaa agcgatttca aaaaaggagg gcgttatatg ttcgaaatta gaaatttgag
     7081 tctctctttt gcaggcaggc ggttgctaga gccaacagat ttgatatttg aaaggggaaa
     7141 agtatataca atatatggga agtcaggcgt aggaaagtct tctttactga ataaaattgg
     7201 tttgctctct gctacggatc ctagtgtttc ttatttcttc gatggaaaag agattgatat
     7261 cgaaaataag aaatcagtct ctgtctttat agctgaagaa gttgcctttg tatttcaggg
     7321 gcgaaatcta ataaatgatt tgaccgtatt tgaaaattta agactagctt taaactttta
     7381 tgacttgagt ccagatgaaa tagaaagcaa aattgataca gtattggcgg atttacagat
     7441 ttcttcttta aagcatgctt atccagaaga tttatccggt ggtgaagaac aacgagtggc
     7501 aatcgcaaga gccttagtta caggaaagac tctcatctta gctgatgaac caacaagttc
     7561 tttggataaa gaaaatagag aaaaagtctc cgccttgtta attgatttag ctcacaaata
     7621 tcataaaatt gtattgattg tttcgcatga tgaggcgatg attgcaatag gagatgttca
     7681 gcttcatttt aaagaccata aattagttgg gaattgtctt attttgaatt ctgatgaagg
     7741 gataaaggat tctaagaagt ggtcctcctg tttgtcgtct tctcatacga agctatccgt
     7801 tttgaaacat agaaggcctt ttttacctag attattagcg ttttttatct ctcttgtagt
     7861 tgctatagca gtaacctcta ttaactttca gtccttattt gcagataagt atcaccaact
     7921 ggtgaacaac tcactcgaaa atggcttctt ggtgattaat gattcgcttc atttacaaac
     7981 tacaaaagtg ttggatgatt ttctcagttt tgataaggag gaaatcacct caattagcac
     8041 aagtcagaat attcaaaccg tcaatcctta tatagagttt ctctctttgg gtatgacgtt
     8101 tgataattca aaagactatt cacaacttca aaagaacttt cagccaactt tgactattga
     8161 tggtcagacc agaagcttga caagaaattt ttcaattcaa cccttgtatc agacaaatac
     8221 aacacagagg cagatagagt attttgatag gagcaatgaa aaagggattt atctatctga
     8281 gcaattcatt tcagatgaaa aattaccaaa tatagtttcg ggaactaccg tgacactgac
     8341 tttttatatt ccaatttctt tatatgaatc aagtatagag aaagagggga atatattgaa
     8401 aggagatggc gatttatttg tcaaagtgga taaaacatat cctgttttag ggattgttaa
     8461 aaaaagttat ccgtttgaat attcccctta tgggaacacc ctatttatga atattgctga
     8521 aatggaagaa ttgcaaaatg aagcaattca acagcatccc atgacgaaga tggctttaga
     8581 tggttttcct ttgaaatcat ggatgccgag tgcgattcat gtgttactaa aggatagcgg
     8641 tgctattcct gaagaattga gtagaataag agcaatctct tcacaaatta ctattttatc
     8701 atcatatgaa aactacgaag aatttaataa aggactcacc tatatcaggc aatttttaat
     8761 gttgctatcc ctagtcttac tcatccttgt catcgcagta ttgtcctttg ttttcttttt
     8821 gctcaatcgt cctcgacgct ttgaagtagg gattttaaaa tctttgggat acagtactca
     8881 aaatattgtt tggcttttct taaaagaatt aattggttat ggtaaaacaa tttcgatatt
     8941 agcaagttgt ttactcgtca ttctttccat tttagcaatg caagtgctta aattggaaat
     9001 ttcagatgtt tttaaattct atctaacttc cgttttcacc ttaattggat tatcagtctc
     9061 agtactgata ataagtggct tactacctat atacacaact tgtaggcaaa cagttgtcga
     9121 tactatccga aagaatggat gaggtgatat catgaaacat aagataatga aaaaaataat
     9181 agtggtagtg tttgctatcc catggttaac atttttaagt caagtacatg cagattatgt
     9241 aagtaagtct agttctttag acggttatag cttggtaggc ttgaatgttc ttaatgtgac
     9301 ttttaatgct tctggctatt ctgatactta tagtggcagt gtgtcaaata tgtatttcac
     9361 tgactgggct tggtttccta atacgataag taatcgttcc acttggaaaa gttcgattcc
     9421 atatggtcaa cgcgcaaatg gtacagtcca tataggtgta ggagtaaatt cgccttgggg
     9481 agcggttaat ctctggggcg gacaaaatta cttttcttta gatttttaac agaaataatc
     9541 aaagttagat agaatgaata agaatgctct tgatgatggt atcaagagta ttttatgtta
     9601 ttcagattaa tgcaaacatt gccctttctt gtcgcaggct ccgtttcatg atacaataga
     9661 aggagtgatt ttagaaagcg tgagaaacat gatttacttt gataattcag cgacgaccaa
     9721 gccttatcct gaagcccttg aaacctatat gcaggtcgct tcaaaaattt taggaaaccc
     9781 atctagtctc catcgtttgg gagaccaagc aacacgaatc ttagatgctt ctcgccaaca
     9841 gattgcagat ttagtcggta agaaaagcga tgaaatcttc tttacctctg gtggaacaga
     9901 aggggataac tggcttatca agggtgtggc ctttgaaaaa gctcagtttg gcaagcacat
     9961 cattgtttca gccattgaac atccagcagt caaagagtca gccctctggt tgaaaagtca
    10021 aggatttgaa gtggattttg ctccagttga taagaaaggc ttggtcgatg ttgaggcgtt
    10081 agcaggtttg atacggcatg atacaatcct cgtttccatc atggctgtga acaatgaaat
    10141 cggctctatc caacctattg aggctatttc agaattcttg gcagacaagc cgactatttc
    10201 cttccacgtt gatgcggttc aggcgcttgc caaaattccg actgaaaagt atctgacaga
    10261 acgggtggac tgcgcgactt tctctagtca caagttccac ggggttcgag gtgttggctt
    10321 tgtctatatc aaatctggca agaagattac acctcttctt acaggtggtg gccaggagcg
    10381 agattatcgt tcgacaactg aaaatgtggc agggattgca gcgacagcca aggccctccg
    10441 tttgtctatg gaaaagctag atatctttag gagcaagact gggcagatga aggcagtgat
    10501 tcgccaagct cttctgaact atccggatat ttttgtcttt tcagatgagg aaaactttgc
    10561 acctcatatt ctgacttttg gaatcaaagg tgttcgaggt gaagtcatcg ttcacgcctt
    10621 tgaagactat gatattttca tctcaacaac ctcagcttgt tcatctaagg caggaaaacc
    10681 agccggtacc ttgattgcca tgggagtgga caaagataag gccaagtcag ctgtgcgtct
    10741 tagcctagac ttggaaaatg atatgagtca ggtcgagcag tttttgacca agttaaaatt
    10801 gatttacaat caaactagaa aagtaagata ggagcattca tgcagtattc agaaattatg
    10861 attcgctacg gagagttgtc aaccaagggt aaaaaccgta tgcgtttcat caataaactt
    10921 cgtaataata tttcggacgt tttgtctatc tatacccaag ttaaggtaac agcagatcgc
    10981 gaccgtgccc acgcttacct caatggagct gattacacag cagttgcaga atctctcaaa
    11041 caagtttttg gaattcaaaa cttttctcct gtttataagg ttgaaaaatc tgtagaagtt
    11101 ttgaagtctt ctgtccaaga gattatgcgg gacatctaca aggaaggtat gacctttaag
    11161 atttctagca agcgtagcga ccacaacttt gaacttgata gtcgtgaact caaccaaaca
    11221 cttggagggg ctgtattcga agccattcca aatgtgcaag ttcaaatgaa aagtcctgac
    11281 atcaatcttc aggtggagat tcgtgaagaa gcagcctatc tttcttatga aaccattcgt
    11341 ggggctggtg gtttgccagt tggaacttca ggtaaaggga tgctcatgtt gtcaggaggg
    11401 attgactcac ctgtagcagg ttatcttgct cttaagcgtg gggtggatat cgaggcagtt
    11461 cactttgcta gtccaccata tactagtcct ggtgccctca agaaagcgca ggacttgacc
    11521 cgtaaattga ccaagtttgg cggaaatatc cagtttatcg aggtgccttt cacagagatt
    11581 caagaggaaa tcaaagccaa agcgccagaa gcttatttga tgactctaac tcgtcgcttt
    11641 atgatgcgga ttactgaccg tattcgtgag gtacgaaatg gtttggttat catcaatggg
    11701 gaaagtctag gtcaagtagc cagccaaacc cttgaaagta tgaaggctat caatgctgtt
    11761 accaacactc ccatcattcg tcctgtggtt accatggaca agttggaaat cattgacatc
    11821 gcccaggaaa tcgatacctt tgacatttca atccaaccgt ttgaagactg ttgtaccatt
    11881 tttgcaccag atcgtccaaa aacaaatcct aaaattaaga atgcggagca gtacgaagcg
    11941 cgtatggatg ttgaaggctt ggttgagcga gcagtggctg gaatcatgat tactgaaatc
    12001 acacctcaag ccgaaaaaga tgaagttgat gacttgattg acaatctgct ctaattcaga
    12061 aaatccaaaa gaatagcgaa aatcagtaaa aaaagttagt tttttctcta aaaacaggta
    12121 aaaaactaac tttttttatt tttatgatat aatgatataa aattttgaat atagagagtt
    12181 ttctgacaat gaatcaatcc tacttttatc taaaaatgaa agaacacaaa ctcaaggttc
    12241 cttatacagg taaggagcgc cgtgtacgta ttcttcttcc taaagattat gagaaagata
    12301 cagaccgttc ctatcctgtt gtatactttc atgacgggca aaatgttttt tatagcaaag
    12361 agtctttcat tggatattca tggaagatta tcccagctat caaacgaaat ccggatatca
    12421 gtcgcatgat tgtcgttgct attgacaatg atggtatggg gcgaatgaat gagtatgcgg
    12481 cttggaagtt ccaagaatct cctatcccag agcagcagtt tggtggtaag ggtgtggagt
    12541 atgctgagtt tgtcatggag gtggtcaagc cttttatcga tgagacctat cgtacaaaag
    12601 cagactgcca gcatacggct atgattggtt cctcactagg aggcaatatt acccagttta
    12661 tcggtttgga ataccaagac caaattggtt gcttgggcgt tttttcatct gcaaactggc
    12721 tccaccaaga agcctttaac cgctatatcg agtgccagaa actatcgcct gaccagcgca
    12781 tcttcatcta tgtaggaaca gaagaagcag atgatacaga caagaccttg atggatggca
    12841 atatcaaaca agcctatatc gactcgtcgc tttgctatta ccatgatttg atagcagggg
    12901 gagtacatct ggataatctt gtgctaaaag ttcagtctgg tgccatccat agtgaaatcc
    12961 cttggtcaga aaatctacca gattgtctga gattttttgc agaaaaatgg taagttaaga
    13021 aaggaaaaaa cgaaatgcat attgaacatc ttagccactg gagtggtcat cctaaccgtg
    13081 aaatgtacct taaccgttat ggacatggtg ggattccagt tgtggtcttt gcttcatcag
    13141 gtggtagtca caacgaatac tatgattttg gcatgattga tgcctgtgct tcctttatcg
    13201 aggaaggcct tgtccagttc tttaccctat ctagtttgga tagtgagagc tggttggcta
    13261 cttggaaaaa tgctcatgac caagcggaaa tgcaccgtgc ctacgaacgt tatgtgattg
    13321 aggaggccat tcttttatca agcacaagac aggttagttt gatggcatga tgacgacagg
    13381 ttgctctatg ggagcctatc atgcactcaa tttcttcctc cagcatccag atgtctttac
    13441 caaagtgatt gctctcagtg gtgtttacga cgcacgtttc tttgtcggtg attactacaa
    13501 cgatgatgct atttaccaaa actcgccagt agattatatt tggaaccaaa acgatggctg
    13561 gtttattgac cgttaccgtc aggcagagat tgtgctgtgt acggggcttg gagcctggga
    13621 acaagatggt ttaccatcct tttacaagct caaagaagcc tttgaccaga aacaaattcc
    13681 agcctggttt gctgaatggg gacatgatgt cgcccatgac tgggaatggt ggcgtaaaca
    13741 aatgccttat ttcctcggta atctctattt ataaaaggag ttacctatga attaccttgt
    13801 tatttctccc tactatccac aaaactttca acagtttacc atcgaactag ctaataaagg
    13861 catcacagtc ttgggaattg gtcaagagtc ttacgagcaa ttggatgagc ccttgcgcaa
    13921 tagcttgacc gagtattttc gtgttgataa tcttgagaac atagatgaag tcaaacgtgc
    13981 agttgctttt ctcttttata aacatggtcc aattggccgc atcgagtctc acaatgaata
    14041 ctggcttgag ctagacgcaa cactcagaga acaattcaat gtttttggtg ccaaaccaga
    14101 ggatctcaaa aagacgaaat ataagtctga aatgaagaaa cttttcaaaa aagcaggtgt
    14161 tcctgtggta cctggagctg ttatcaagac ggaagcagat gttgatcaag cagtgaaaga
    14221 aatcggtctt ccaatgattg ccaaacctga taatggagtg ggagcagccg caacctttaa
    14281 acttgagaca gaagacgata tcaatcactt caagcaagaa tgggaccatt caacccttta
    14341 tttctttgaa aaatttgtca cttccagcga aatctgtacc tttgacgggc tcgtggacaa
    14401 ggatggaaag attgtcttct caacaacctt tgactacgcc tatacaccgc ttgacctcat
    14461 gatttataag atggacaatt cttattatgt gctcaaggat atggatccta aactgcgcaa
    14521 gtatggggaa gcaattgtca aagaatttgg tatgaaagaa cggtttttcc atattgagtt
    14581 cttccgtgag ggggacgatt atattaccat cgagtacaat aaccgccctg caggtggttt
    14641 taccattgat gtttataact ttgctcattc cttggacctt tatcgtggct atgcagctat
    14701 tgtcgcagga gaggagttcc cggcgtcaga ctttgaaact cagtattgtt tggctacttc
    14761 tcgccgtgca aatgctcact atgtttattc agaagaggat ttgcttgcca aatatagcca
    14821 gcagttcaag gttaaaaaag tcatgccagc tgccttcgcg gaacttcaag gagattacct
    14881 gtatatgctg accactccga gtcgacaaga aatggagcag atgattgcag atttcggaca
    14941 acgtcaagaa taagaactat cggattaagg aaattaactc ccttaatcct tttgttttgt
    15001 ctgataaaaa ataagagcat cccaacaagg tagctatcat aaaacttgtt cgataactat
    15061 ttgaagcagg attaggtggt cagaaattaa attttaatat ttcaattgag tcatagtatt
    15121 gtgtttgcgt atccttaaat cagctaaaag gatccatgac gacacctata cgatatagtt
    15181 ttcaagatac caaacaagtc tattaatatt caatgaaaat caaagagcaa actaggaagc
    15241 tagccgcagg tttctcaaaa cactgttttg aggttgtgga tagaactgac agagtcagta
    15301 tcatatacct acggcaaggt gaagctgacg tggtttgaag agattttcga agagtataaa
    15361 atattcaggt gacgcataga tatagttaat tgaagctttg tttgaaatct gataaaataa
    15421 tgatattact aagttttaaa aactaaagaa aagggaagat atgattacag gcgaattaaa
    15481 aaataaaatc gatcagctgt gggaaattct ttggacagaa ggaaacgcaa atcctttaac
    15541 aaatattgaa cagttgactt atctcttatt tatgaaagat ttggatagtg tcgagcttgg
    15601 acgtgaaagt gatgctgaat ttctagggat tccttatgag ggagtttttc caaaagataa
    15661 acctgaatac cgttggtcaa cttttaaaaa tataggagat gctcaggaag tttatcgttt
    15721 aatgactcag gagatttttc cgtttattaa aaatctcaag ggggatacag atgatacagc
    15781 cttttcacga tatatgcgag aagctatttt tcaaataaat aaacctgcta cgcttcaaaa
    15841 ggcaatttct atcttagatg tttttccaac taggggatta gatgtagatt ttgataatga
    15901 caaacaaagt attactgata tcggagatat ctatgaatat ctgttatcaa aattgtcgac
    15961 cgcaggtaaa aatggacagt tccgtacacc tcgtcacatc atcgatatga tggttgagtt
    16021 gatgcaaccg actatcaaag atatcatctc agatcccgct atgggttctg ctggcttctt
    16081 agtatctgct agccgttact taaagcgtaa gaaagatgaa tgggaaacca atacagataa
    16141 tatcaatcat tttcataatc agatgtttca tggaaatgat acggatacga ctatgttgag
    16201 acttggggcg atgaacatga tgctacatgg agtagaaaat ccacaaatca gttaccttga
    16261 ctcgctgtct caagataatg aagaagccga taaatatact ttggttttag caaatcctcc
    16321 ttttaagggc tcacttgact acaattcaac ctctaatgac cttcttgcaa ccgtaaaaac
    16381 caaaaaaaca gaattactct ttctttctct tttcttgcga actttaaaac caggtggacg
    16441 agcagcagtt atcgtacctg atggtgtcct ttttggttcg tctaaagctc ataaaggaat
    16501 tcgtcaggaa attgtagaga atcataagct tgatgctgta atctcaatgc ctagtggtgt
    16561 gttcaagcct tatgctggag tttcaactgc cattctcatc tttacaaaaa ctggtaatgg
    16621 tggtactgac aaagtctggt tttacgatat gaaagcggat ggtttaagtt tggatgataa
    16681 gcgacaaccg attagcgaca atgatattcc agatattatc gaacgctttc atcatcttga
    16741 aaaagaagca gaacgtcaga gaacggatca atctttcttt gttccagttg ctgagataaa
    16801 ggaaaatgat tatgatttgt ctatcaataa atataaagag attgagtatg aaaaagttga
    16861 gtatgaacca acagaggtca tcttaaagaa aatcaatgat ttagaaaaag aaattcaagc
    16921 tggcttggct gaattagaaa aattactcaa gtagagaggt ggctgtatga aaaaagtgaa
    16981 gttgggggaa gtcttatctc taaaaaaagg caagaaagcc actgtacttg ctgaacaaac
    17041 aactctaagc caacgttata ttcaaataga tgatttaaga aataataata atttaaaatt
    17101 cactgaaagt ttaaatatga ctgaagcact cccagatgat attctgatag catgggatgg
    17161 agctaatgca ggaacagttg gttatggatt atcgggagct gttggtagta caattacggt
    17221 cttaaaaaag aatgagcgat acaaagaaaa aattatatca gattacttgg gagtcttttt
    17281 ggaaagtaaa tcgcagtatt tacgagaaca ttcaacaggt gcaacaattc ctcatttaaa
    17341 caagaatata ttacttgatt tacaattaga attgctaggt atcgaagaac aagagaacat
    17401 tatctgtatt cttaatacga ttaaaaggct tattactaaa agaaaattgc agttagatga
    17461 actaaacttg ctcgtcaaat cccgatttaa cgagatgttt ggggaaaata aaatatttga
    17521 aagcattgat aacttatttg atattataga tggtgatagg ggcaaaaatt atcctaaatc
    17581 agatgagttg tttagtgagg agtactgttt atttttaaat acaaagaatg ttactaaaaa
    17641 cggattttca ttcgatacaa agcaatttat cactaaaaca aaggataaat tacttcgaaa
    17701 aggcaaactt gagcgttatg atatagtctt gacaacaaga ggtactgttg gaaatgtagc
    17761 gtactacgat gaattaataa aatataaaca tttacgtata aattcaggta tggtaatatt
    17821 acgtcccaag acaccaaatc taaatcagaa atttattatc catgttttaa ggaataataa
    17881 ttatagtcga gtgatatcag gaagtgctca gcctcagtta ccaattacaa aattaaaaaa
    17941 aatacttctc cccctccccc cactagccct ccaaaatgag ttcgcagact ttgtagccca
    18001 ggtcgacaaa tcacaattgg caatccaaaa atctctggaa gaacttgaaa ctttgaagaa
    18061 atctctgatg caggagtatt ttggctgata ttctgccatt gtaattacgg taatgatttg
    18121 ttataatact tcaaaggagg aaatcagatg gtagtaaaaa caagaaaaca aggaaattca
    18181 atcaccatta cgattccaag tgaatttaat attccaagtg gtgttaaata cgaagcgaaa
    18241 ttgttaccaa gtggtgagat tatctttact cctgaagaat tggggcagca ggtttcttat
    18301 gtatctgatg atgcctttga cttaaattta gataaaatat ttgacgaata cgacgatgtt
    18361 ttcaaagctt tggtggaaaa atgacaatct atctgacaga aaagcaaatt gaaaaaataa
    18421 atgctttagc aattcaacgg tattctccaa atgagaaaat tcaaacagtt agttcttctg
    18481 ccttaaatat gattgtgaac ttaccagaac aatttgtctt tgggaagtct ctttatccaa
    18541 caatttttga taaagcaacg atactatttg tccaattgat aaagaagcat gtttttgcta
    18601 atgctaataa aagaactgct ttcttcgttt tggtcaaatt tttacaatta aacggctatc
    18661 gtttttctgt aacggtagaa gaagcagtaa aaatgtgtgt aaccatcgca gtagaagctt
    18721 taactgatga aaaaatgaca agctactcca aatgggtttc tgaacattct gttagagaaa
    18781 aggtcaaaaa gtaacctagt atgctggatt tgaatgagca caagaaaata aatgaacaga
    18841 caatattaga attctgtaat gcagaaactg atattgtctc tttttattga tgaataagaa
    18901 agtgagaaat tatggaatca aaagttacaa ttatcatgca agaaatgtta cctcttttaa
    18961 ataatgaaca attactagcg ttgagagaga gtttagaaca tcatctagta gacggaaaaa
    19021 agcagcagaa gtattcgaat aataacctgt tgcaactatt tattaccgcc aagcaggtag
    19081 agggctgtag ctcaaaaaca attcgttatt accagaggac gattgaaaac ttgtttaatg
    19141 ctattaaaga gtctgtgaca caactcacaa cagatgattt aaggagttat ttagcaaatt
    19201 accagtctga aaaggattgt agtaaggtaa atttagacaa tattaggcgt atattgtctt
    19261 ctttttttgc ttggcttgag caagaggaat atatcattaa aaatcccatt cgacggataa
    19321 agaaaattaa gactgagcaa aatgtgaagg aaacttatac tgatgaacat ttggaaatta
    19381 tgcgtgataa ctgtgaaaat ttgagagatt tggcaataat agacctacta gcatcgacag
    19441 gtatgcgtgt aggggagctt gtacagttga atcgttcaga tattgatttt gaaaacagag
    19501 agtgtgttgt ctttggtaaa ggaaagaagg agagaccagt atattttgac gctcggacga
    19561 aaattcattt aagaaattat cttaacgaca gaaaagatag tcaccctgct ctttttgtaa
    19621 cgttagttgg aaaagtccag aggcttggaa ttgctggtgt agagattcgc ttaagaaagt
    19681 taggagacaa actcggtata caaaaggttc acccacataa gttcagaaga actttagcga
    19741 ctaaggcaat tgataaaggt atgcctatcg aacaagtcca aaaactgcta ggtcatagca
    19801 agattgacac aaccctggcc tatgccatgg tcaatcaaaa taatgtcaag cattcacacc
    19861 aaaaattcat ctcttaaaag caaatcccga tattccgagg aggtggttgc atgaagaaag
    19921 tgaaattagg ggaagtggct acttttatca atggctatgc ttttaaacct caagattggt
    19981 catctgaagg gagagagatt atcagaatac agaatctgac taaaacttca acagagataa
    20041 attattattc gggtacgatt gataaaaaat acattgttga agctggtgat atccttattt
    20101 cgtggtcggg tacattaggg gtttttcagt ggtgtggaag atccgcagta ttaaatcagc
    20161 acatttttaa agtggttttt gataagatag atatagataa atcgtatttt aaatatgttg
    20221 ttgaaaaagg tttacaagat gctgtaaaac atactcatgg ttccacaatg aaacatttaa
    20281 ctaaaaaata ttttgataat attatagttc catatacaaa tttgggagag caacaaagaa
    20341 ttgcaagtga gctggatttg ttaagcaagc tgattttaag gagacaagaa caacttgaag
    20401 agcttaatct acttgtaaaa tcccgattta acgagatgtt tggggatgtt attctaaatg
    20461 aaaaagaatg gaaagttagc aaatggaacg agattctaac aataagaaat ggtaaaaatc
    20521 aaaaacaggt tgaagatgct gatgggaaat ttcctattta tggaagtggg ggaattatgg
    20581 gatatgctaa agattggata gtgaagaaaa attcagttat tattggacgt aaaggaaata
    20641 taaataaacc tattttagtt agagaaaatt tttggaatgt agatacagca tttggattag
    20701 agcctgtttt agaaaaaata aactcagaat atttattcta tttttgtcaa ttatacaatt
    20761 ttgagaagtt aaataaggct gtaacaatac ctagtttaac taaatcagat ttattaaata
    20821 tttcc
//
LOCUS       DAVLTT010000033        20761 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLTT010000033 DAVLTT010000000
VERSION     DAVLTT010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.033"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            52..681
                     /locus_tag="VYN15_001323"
     CDS             52..681
                     /locus_tag="VYN15_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1452636.1"
                     /translation="MTILISICVIFLGTILGVVLAFGQRSKFKPLVWLANLYVWIFRG
                     TPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILIISMNSGAYVSETVRAGINA
                     VPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEFITIIKDSSLLSAIGVMEL
                     WNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFEKHMGQGDKK"
     gene            681..1415
                     /locus_tag="VYN15_001324"
     CDS             681..1415
                     /locus_tag="VYN15_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1452637.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            1569..2426
                     /locus_tag="VYN15_001325"
     CDS             1569..2426
                     /locus_tag="VYN15_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV1452638.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            2568..3440
                     /locus_tag="VYN15_001326"
     CDS             2568..3440
                     /locus_tag="VYN15_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV1452639.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMAFALQDKQLLKEQLEKAEVVLLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDTTASALTSFPKGTILVEKGPATRVWQAGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            3722..4405
                     /gene="rpiA"
                     /locus_tag="VYN15_001327"
     CDS             3722..4405
                     /gene="rpiA"
                     /locus_tag="VYN15_001327"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV1452640.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            4419..5630
                     /locus_tag="VYN15_001328"
     CDS             4419..5630
                     /locus_tag="VYN15_001328"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV1452641.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            5632..6192
                     /locus_tag="VYN15_001329"
     CDS             5632..6192
                     /locus_tag="VYN15_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV1452642.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKNNKGDTQ"
     gene            6189..6998
                     /locus_tag="VYN15_001330"
     CDS             6189..6998
                     /locus_tag="VYN15_001330"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1452643.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            7474..8454
                     /locus_tag="VYN15_001331"
                     /pseudo
     CDS             7474..8454
                     /locus_tag="VYN15_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            8479..8991
                     /locus_tag="VYN15_001332"
     CDS             8479..8991
                     /locus_tag="VYN15_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV1452644.1"
                     /translation="MSAQITINHKKVRYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTADFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            9649..10359
                     /gene="deoD"
                     /locus_tag="VYN15_001333"
     CDS             9649..10359
                     /gene="deoD"
                     /locus_tag="VYN15_001333"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1452645.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(10382..10906)
                     /locus_tag="VYN15_001334"
     CDS             complement(10382..10906)
                     /locus_tag="VYN15_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV1452646.1"
                     /translation="MKIAIIGYSGSGKSTIAEKLSNYYSIPKLHMDTLQFQPDWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAVDCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(10959..11195)
                     /locus_tag="VYN15_001335"
     CDS             complement(10959..11195)
                     /locus_tag="VYN15_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV1452647.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLVK"
     gene            complement(11263..12183)
                     /locus_tag="VYN15_001336"
     CDS             complement(11263..12183)
                     /locus_tag="VYN15_001336"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV1452648.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            12373..12776
                     /locus_tag="VYN15_001337"
                     /pseudo
     CDS             12373..12776
                     /locus_tag="VYN15_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12992..13573
                     /locus_tag="VYN15_001338"
     CDS             12992..13573
                     /locus_tag="VYN15_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1452649.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            13570..14847
                     /locus_tag="VYN15_001339"
     CDS             13570..14847
                     /locus_tag="VYN15_001339"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV1452650.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDMIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            14865..15527
                     /gene="deoC"
                     /locus_tag="VYN15_001340"
     CDS             14865..15527
                     /gene="deoC"
                     /locus_tag="VYN15_001340"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV1452651.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLSQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            15514..15903
                     /locus_tag="VYN15_001341"
     CDS             15514..15903
                     /locus_tag="VYN15_001341"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1452652.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            15993..17045
                     /locus_tag="VYN15_001342"
     CDS             15993..17045
                     /locus_tag="VYN15_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV1452653.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDIANKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            17189..18724
                     /locus_tag="VYN15_001343"
     CDS             17189..18724
                     /locus_tag="VYN15_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1452654.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDSLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            18717..19775
                     /locus_tag="VYN15_001344"
     CDS             18717..19775
                     /locus_tag="VYN15_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1452655.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            19778..20734
                     /locus_tag="VYN15_001345"
     CDS             19778..20734
                     /locus_tag="VYN15_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1452656.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         6075 a         3697 c         4800 g         6189 t
ORIGIN      
        1 aatttttctt ttttacctaa gtatttacct tattttaact atggggctgt tgtgacgatt
       61 cttatttcta tctgtgttat ctttttggga actattttgg gtgttgtctt ggcttttggg
      121 caacgttcaa agtttaaacc gcttgtttgg ttggccaact tgtacgtttg gattttccgt
      181 gggacaccga tgatggttca aattatgatt gcctttgctc ttatgcatat caatgctccg
      241 actattcaga ttggaatttt aggtgttgat ttttcgcgtc tgattccagg gattttgatt
      301 atctctatga atagtggtgc ttatgtttcg gagactgttc gtgccggaat caatgcggtt
      361 ccaaaaggtc agctagaagc ggcttattcg ctagggattc gtcctaaaaa tgcgatgcgt
      421 tatgtgattt tgccacaagc agtcaaaaat atcttgccag cattggggaa cgaatttatc
      481 accattatca aggacagctc cctcttatca gctattgggg tcatggagtt gtggaatggg
      541 gctacaacag tttctacaac aacctatcta cctttaacac cacttttatt tgcagcattt
      601 tactacttga ttatgacctc tattctgaca gtagccttga aagcttttga aaaacatatg
      661 ggacaaggag ataagaaata atgacagaaa ccttgataaa aattgaaaat ttacataaat
      721 cttttggaaa gaatgaagta ttgaagggca tcaacctcga gattaaaaga ggagaagttg
      781 tcgttatcat cggtccttca gggagtggga aatctacctt gcttcgctct atgaatttgt
      841 tggaggaagc aaccaagggg aagcttatct ttgagggagt cgatattacg gacaagaaga
      901 atgacctgtt tgccatgcgt gagaagatgg gcatggtttt ccaacaattt aacctctttc
      961 ctaatatgac tgtgatggaa aatattacct tgtcacctat caagactaaa ggtgaaagca
     1021 gggaagttgc tgagaagaga gcccaagagc ttttggaaaa agttggtttg ccagataagg
     1081 cagacgctta tccacagagt ctgtcgggtg ggcaacaaca acggattgcc atcgcgcgtg
     1141 ggttggctat ggaaccagat gttttgctct ttgacgaacc aacttcagcc ttggatcctg
     1201 aaatggtagg tgaggtattg gctgttatgc aagaccttgc caagtcagga atgactatgg
     1261 ttatcgtaac acatgagatg ggatttgccc gtgaggtggc agatcgtgtt atctttatgg
     1321 cagacggtgt ggttgttgaa gatgggacac ctgagcagat ttttgaacaa acccaagaac
     1381 aacggactaa agatttcttg agtaaggttt tataatctat tttaaaattt caagacaaga
     1441 ttagtgaaaa gttcaaccag agctttttct tatagtttga aactatagga taacctagga
     1501 aagaagtgtt agagggcact agcagttttt ggtataatgg aagatatttg aaagaaaaga
     1561 gaagtgatat gacacagatt attgatggga aagctttagc ggccaaattg caggggcagt
     1621 tggctgaaaa gactgcaaaa ttaaaggaag aaacagctct agtgcctggt ttggtagtga
     1681 ttttggttgg ggataatcca gccagccaag tctacgttcg caacaaggag aggtcagctc
     1741 ttgcggctgg ttcccgtagc gaagtagtgc gagttccaga gactattact caagaggaat
     1801 tgttagacct gattgctaaa tataatcagg atccagcttg gcatgggatt ttggtccagt
     1861 tgccattacc aaaacatatc gatgaagagg cggttttatt agccattgac ccagaaaagg
     1921 atgtggatgg tttccatccc ctaaacatgg gacgtctttg gtctggacat ccagtcatga
     1981 ttccctcgac acctgcagga attatggaaa tgtttcatga atatgggatt gacttggaag
     2041 gtaaaaatgc ggtcgtaatc ggtcgttcaa atatcgttgg aaaacctatg gctcagcttc
     2101 ttttggctaa aaatgcgaca gtaaccttgg cccactcacg aactcataat cttgccaagg
     2161 tggctgctaa agcagatatt cttgtagtcg caatcggccg cgccaagttt gtgactgctg
     2221 actttgtcaa accaggtgcg gttgtcattg acgttgggat gaatcgagat gaaaatggga
     2281 agctctgtgg agatgttgat tatgaggcag ttgcaccact tgctagccat atcacgccag
     2341 tccctggagg tgtcggtcct atgaccatta ccatgctgat ggagcaaact tatcaagcag
     2401 cacttcggac attggataga aaataagaga agcattcgat taatagagtg tattttctat
     2461 agctatatct aaaatggcag aaatgaatat taaattttag atataagatt acaaaaggag
     2521 gtctgcgtct cctttttatt gtataataaa agtgagagga aaaaaggatg aaagtgatta
     2581 atcaaacctt attagaaaaa gttattattg aacgttctcg ttcaagtcat aaaggagatt
     2641 atggtcgtct gctgctgctt ggtggtactt atccttatgg aggtgccatc atcatggctg
     2701 ctttagcagc tgtaaaaagc ggtgcaggat tggtgaccgt tggaacggac agggaaaata
     2761 tccctgctct gcacagtcat ttacctgagg ctatggcctt tgctcttcaa gacaagcaat
     2821 tgttaaaaga gcagttggag aaggcagaag ttgttttgct gggacctggt ttaggagaca
     2881 atgcttttgg agaagattta gttaaacagg tctttgctgg cttaaaacag aatcagattt
     2941 tgattgtaga cggaggtgct ttgactattc ttgctaggac aagtctgtca tttccttcta
     3001 gccagcttat cctaactccc caccaaaagg agtgggaaaa actgtctgga attacgattg
     3061 aaaagcaaaa ggaagataca acggctagtg ccctgacttc tttccctaaa ggaacaattt
     3121 tggtggagaa aggtccggct actcgtgttt ggcaagctgg ccagtctgat tattaccagt
     3181 tacaggttgg cggtccctat caggcaactg ggggaatggg agatactctg gctgggatga
     3241 tcgcaggatt tgtaggccaa ttccgacagg ccagtctcta cgagcgtgta gcagtagcga
     3301 cccatcttca ttcagccata gcccaagaac tatctcaaga aaattatgtg gtcttaccga
     3361 cggaaatcag caggtatctt cccaaaataa tgaaaattat ttgtcaacaa gagagggtaa
     3421 gcaaagataa acttgtttaa aatagacaga taaatctact tccttctctt aatttatgat
     3481 tcttgaaatg cgcctgcttt aaggctaaac tagacgtatc aaagttaaga gtttgttttt
     3541 gtaactggaa agagatgaac aaatcaaata cataaaagat aaactcattt ttattcgttt
     3601 ggtaaaaata aaatgcatat ttttaaagaa agattgatga aaaatgtaga tttgatgttt
     3661 ttacttgaat aaaaagcggt ttcatagtaa aataagaact gagaatgatg gaggtaaatc
     3721 ggtggaaaat ctgaagaaaa tggcaggtat caaggctgct gagttcgtga gcgatggaat
     3781 ggtcgttgga cttggaacag gctcgactgc ctattatttt gtcgaagaaa tcggtcgtcg
     3841 tatcaaggaa gaaggattac agattacagc tgtaacaact tctagtgtga ccactaaaca
     3901 ggcagaaggc cttaatatcc cgctcaagtc tattgaccaa gtagactttg tcgatgtgac
     3961 ggttgatggc gcggatgaag tggatagtca gtttaatgga atcaaaggcg gtggtggtgc
     4021 ccttctcatg gaaaaggtgg tcgcaacacc atcaaaagaa tacatttggg tggtggatga
     4081 aagcaagctg gtcgaaaaac taggtgcttt taaattgcca gtagaagtgg ttcagtatgg
     4141 tgcagagcag gtctttcgtc attttgaacg agctggctac aaaccaagtt tccgtgaaaa
     4201 agacggccaa cgttttgtga cggatatgca gaattttatc attgacctcg ccttggatgt
     4261 cattgaaaat ccaattgctt ttggacaaga attggaccat gtcgttggtg ttgtggagca
     4321 tggtttattc aaccaaatgg tggataaggt aatcgttgct ggacgagatg gagttcagat
     4381 ttcaacttca aaaaaaggaa aatagaaggg ggcataagat gtctaaattt aatcgtattc
     4441 atttggtggt actggattct gtaggaatcg gtgcagcacc agatgctaat aactttgtca
     4501 atgcaggggt tccagatgga gcttctgaca cactgggaca catttcaaaa acagttggtt
     4561 tgaatgtccc aaacatggct aaaataggtc ttggaaatat tcctcgtgaa actcctctta
     4621 agaccgtagc agctgaaatc aatccaactg gatatgcaac aaaattagag gaagtatctc
     4681 ttggtaagga tactatgact ggacactggg aaatcatggg actcaacatt actgagcctt
     4741 tcgatacttt ctggaacgga ttcccagaag aaatcctgac aaaaatcgaa gaattctcag
     4801 gacgcaaggt tattcgtgaa gccaacaaac cttattcagg aacggctgtt atcgatgatt
     4861 ttggaccacg tcagatggaa actggagagt tgattatcta tacttcagct gaccctgttt
     4921 tgcagattgc tgcccacgaa gacattattc ctttggatga attgtaccgt atctgtgaat
     4981 acgctcgttc gattaccctt gagcgtcctg cccttcttgg tcgcatcatt gctcgccctt
     5041 atgtaggtga accaggtaac ttcactcgta cggcaaaccg tcgtgacttg gctgtatctc
     5101 cattttcccc aactgttttg gataaattga atgaggctgg tatcgatact tatgctgtgg
     5161 gtaaaatcaa cgatatcttt aacggtgctg gtatcaacca tgacatgggt cacaacaagt
     5221 caaatagtca tggaattgat acactattga agactatggg acttgctgag tttgaaaaag
     5281 gattctcatt tacaaaccta gttgactttg atgcccttta cggccatcgt cgtaatgctc
     5341 acggttaccg tgattgcttg catgagtttg atgaacgctt acctgaaatt atcgcagcta
     5401 tgagagagaa tgaccttctc ttgattactg cggaccatgg aaatgaccca acgtatgcag
     5461 gaacggatca cactcgggaa tatattccat tgttggccta tagccctgcc tttaaaggaa
     5521 atggtctcat tccagtagga cattttgcag atatttcagc gactgttgcc gataactttg
     5581 gtgtggaaac tgctatgatt ggggaaagtt tcttagataa attggtataa gatgacgcgc
     5641 tatgctttgc tggtgagagg tatcaatgtt ggtggtaaga ataaggtcgt catggcggag
     5701 cttcgtcaag aattgacaaa cttgggactg gaaaaggttg agagctacat caatagtggc
     5761 aatattttct ttacttcgat agattccaaa gcccaattgg ttgaaaagct agagactttc
     5821 tttgcagtcc attatccatt tattcagagc ttttctttac tgagtctaga ggactttgag
     5881 gcggaacttg aaaatctacc agcttggtgg agcagagact tggcacgaaa agattttctc
     5941 ttttacactg agggtttgga tgtggaccaa gtcatcgcga cagttgaaag tttagagctg
     6001 aaagatgaag tgctttattt tggaaaactt gggattttct gggggaaatt ttctgaagaa
     6061 tcctattcta agactgccta tcataagtac ttgctgaagg tgcctttcta ccgccacatt
     6121 actattcgta atgctaaaac ctttgacaaa attggtcaaa tgctaaaaaa taataaagga
     6181 gacacacaat gacattttta aacaaaatcc atgaaactgc tactttcctg aaagaaaagg
     6241 gaattgcagc ccctgagttc ggtctaatcc ttggatcagg acttggagaa ttggcagaag
     6301 aaatcgaaaa tccagttgta gtagactatg ctgagattcc aaactggggc cgttcaacag
     6361 tagtcggtca tgctggtaaa ttggtatatg gtgaactggc aggtcgcaag gtcttggctc
     6421 ttcaagggcg tttccatttc tatgaaggga atcctctgga agtggtgact ttcccagttc
     6481 gtgtgatgaa agttcttgga tgtgaaggtg ttattgtaac caatgcagct ggcggtatcg
     6541 gatttggtcc tggtaccttg atggctatct cagaccatat caacatgacg gggcaaaatc
     6601 cattgatggg tgaaaacttg gatgactttg gcccacgttt cccagatatg tctagggcct
     6661 acacaccaga ataccgtgcc actgcccatg aagtggctaa aaaacttaat atcaagcttg
     6721 atgaaggtgt ctatatcgga gttactggtc cgacttatga aacaccagca gaaattcgtt
     6781 cctataagac actgggagca gatgcagttg gtatgtctac ggttcctgaa gttatcgtgg
     6841 cagcccactc tggcttgaaa gttctgggaa tttcatgtat cactaacttt gcggccggtt
     6901 tccaagaaga actcaatcac gaagaagttg tagaagtgac tgaacgtgtt aaaggtgatt
     6961 tcaaaggctt gcttaaagcg attcttgctg aattgtaaga aaaaagattt aaaaggggga
     7021 gtgcctctgt tttttcagga ttgactgcct atccggatta aagaagaaac agaggaatac
     7081 tatgagcttc ttcctgctct tataactgaa agaagcggaa gaataggtat gtctgatctg
     7141 atagccagca ttgtgaaaga caagattcta ggatactagc attagcttcc tagccaagca
     7201 gactagtatg ataaggagag atgagaatga attgactttc tgaatttctc agtcttatca
     7261 tatatagcac aatgagattt cgcttgagtc tgcttgtaaa taaacgaaaa gaaagataag
     7321 aaataatgaa aattggtcaa cgaattatgc gctttggcat aaaaaattaa gtatcggagt
     7381 tgtatctgtt gtagttggct ttgatttcta gctccagctg gaatttcagc caatgaagta
     7441 aagcaagatg taacatctga agtggtaata ggtgtgctag attctaagga ggaattgaaa
     7501 gagtcagaaa atgatgctcc aaaactagaa actcctctta gagaggagcc aagactagct
     7561 cctcaaacgc ttccggaagc aagtgaagtt cttgaaaaca aaagggaaga gtcaaaagta
     7621 gagataacat aaccagctca agcggatgat atccgcaagg ttgttgggga attagccaag
     7681 gatataagta ttactaagtt gtatatgaca ggtcattctc ttggatgtta cctagctcag
     7741 attgcagcgg ttgaagctta ccaaaaatat cctgattttt ataaccatgt attgaggaaa
     7801 gtgacaactt tcagtgctcc taaagtgatt acttccagaa ctgtttggaa tgctaagaat
     7861 ggtttctggg atgttggttt ggaaagtcgt aaattagctg ttagtggaaa aattaagcat
     7921 tatgtggttg ataatgacaa tgttgtgact cccttgattc ataataatcg tgatattgtt
     7981 acatttacag gtaattcacg ctttaaacac cgttctcgtg gctattttga aagtccaatg
     8041 aatgatattc ctaactttaa tattggtaaa caagctacct tggataaaca tggttatcgt
     8101 gatccgaaat tggataaagt gcgattcttt aagaaacagg ctctgcctcg atcttctagt
     8161 caaccaagcg ctgaaccaat ggaaaatatt gccttaggaa aacaggttac tcaaagttcg
     8221 acagttttcg gaggagatgc tagaagagct gtggatggca aagtcgatgg taactatggt
     8281 cacaattctg tcactcatac aaacttccaa tctaagcctt ggtggcaagt agatttggct
     8341 aaagaagaaa ccattcgcca aatcaatatt tacaaccgaa cagacactgc ccaggataga
     8401 ttggcaaact ttgatgtcat tcttttagac agttctggta aagaaattga gtaaaaacgt
     8461 ataacatctc ctaaagatgt gtcagcacaa attacgatta accataaaaa agtgcgctat
     8521 gttcggattg agctagaagg ctataatgcc ctcagtcttg cagaagttga agttttccgc
     8581 tttatagcta cgaatgctga aacggcgaca caagtttcta agccagttca accaatcagt
     8641 cagactcctg tgaaagataa aacattgaca attcaacaca gtggagctta cattgcccgc
     8701 tactccataa cttgggaaga agttccagta gataaagatg gaaaccaagt tgttcgtagt
     8761 cattcttggg aaggaaacgg ttgcaaccag actgcagatt ttgtcctcaa cctcccaatc
     8821 aaagaaaata tgagaaatct gcgagttaag attgagaaaa agacgggcct actatggaat
     8881 agatggcaaa caatctatga aaacagacca attttagctc aaccccaccg taaaattacc
     8941 cattggggta cgacattgaa ttccaaggtg agtgacgatg atgtcttgta atctgatggt
     9001 acaatgacag ttagtttgtc tagtttataa gaaagtacta cctgagcttg aatagaactc
     9061 aggtagctct ctgtgaaaga acaaaattaa tactcaatga aaatcaaaga gcaaactagg
     9121 aaactagctg caggttgctc aaagcactgc tttgaggttg tagataagac tgacgaagtc
     9181 agtcacatat ataatccaag gcgacgttga cgtggtttga agagattttc gaagagtata
     9241 aacagaaagg tagagcgcgt gttctaattt gaacacgagt agaaaacttt tctaaaaaca
     9301 aaaacgaaag gatgggtaaa ctgtattcgc tgaactgaat acgggcgact ctcctctaaa
     9361 tcaaaattaa gaaagaaagg aattgaaccc accctaaaag cagtgggaaa aagatagttg
     9421 gtctagcgag catcgctcac tgcgcccaac tcctattttc ccttcgcttt ttgacgggtt
     9481 tggtatcttt ctcaatataa aatataaaat aaagaaaggt agagcgtgtg ttttgatttg
     9541 aacacgagcg gaaaactcgg aaaatagata atctgactga aaaatcagga tttctcgtcg
     9601 gcttcctaat tttcagtcgt tttcttctcg ctctttgtat cataaattat gtctatccat
     9661 attgctgctc agcagggtga aattgctgat aaaattcttc ttcctgggga tcctcttcgt
     9721 gctaagttta ttgcggagaa tttccttggt gatgctgttt gttttaacga agtgcgtaac
     9781 atgtttggtt acactggtac ttacaagggt caccgtgtat ctgtcatggg aactgggatg
     9841 ggaatgccat ctatttcgat ttatgcgcgt gagttaatcg tagactacgg tgtgaagaaa
     9901 ttgattcgtg tgggaactgc aggttctttg aatgaagagg ttcatgttcg tgaattagtt
     9961 ttggcgcagg cggctgcaac caactcaaac atcgttcgta atgactggcc acagtacgat
    10021 tttccacaaa ttgctagctt tgatttgctt gataaagcct accatatcgc caaagaactt
    10081 ggtatgacta ctcacgttgg gaacgttttg tcatctgatg tcttttactc aaattacttt
    10141 gaaaagaata tcgagcttgg taaatgggga gtcaaggctg tggaaatgga agcagcagct
    10201 ctttactatc ttgctgccca ataccatgtt gatgcgctag ctatcatgac catctctgat
    10261 agcttggtca atccagacga agacacaact gcagaagaac gtcaaaatac cttcactgat
    10321 atgatgaagg ttggtttgga aaccttgatt gcagaataat tatagccaaa aaggaagccc
    10381 tttatgaatt gtaggacttc cttttcttat ccagaaattg atctagctct ctctgatttc
    10441 gaagaatagt gactttatgt gaatattctt ggcaaagttt ttggtaattt tctttttgag
    10501 ttttgctacg cccatcccaa agaatccatc tgataaactc ccactcaaag cgttcagggc
    10561 aatctaccgc catactttct ctgacttttc cacggtattt aagataacgc ttaaaggctc
    10621 taaagagaca ggtcaatggc gaaaaattga gaaagatgat ttggtcagct tcttgcattc
    10681 gttcttggta gtagcaccaa gaataattac catcgatgac ccaagcttta tgcttggtga
    10741 gaaagttttt tatctcggtt aacatccatt cgcagtcact gtcttgccaa tcaggttgaa
    10801 attggagtgt gtccatgtgc agttttggaa tggagtagta gttagataac ttttctgcta
    10861 tagttgactt accagaacca gaatatccga taattgcgat tttcattttc taccttttcc
    10921 tatttggaga caaaaaaaca gcctctatgg actgtttctt atttaacaag tttagctgaa
    10981 agacgagctt tatcgcggct tgctttgttt ttgtgaatca aacctttagt ttctgcttta
    11041 tcgatagctg agctagcagc acggaaaagt tcttcagatg ggtttgcttc gaaagctttt
    11101 atagcagtac gcatagctga tttttgagct gagttctttt cgttttgttt aacgttcaat
    11161 tcagcgcgtt tgatagctga tttaatgttt gccaatgttc ttacctccat atttactaac
    11221 tataccatta tatatgaaaa cttacgtttt gacaagggaa aattactttt ttaagtaaat
    11281 ttcatcgatt tcatggttct tgcttttatg aagaatcact tctgcacgat ttctggttgg
    11341 ttcaatataa ttttgcagat ttgtgagatt gatactgatc cagacctgat gggcaaagga
    11401 ctccacttcc ccaatcggca tctgagtaaa acgataatag tagctatcag ggtcgttttg
    11461 ggctaggctc agcattttca agaaacggtc cagataccaa ctttcaatat catccactcc
    11521 agcatctaca tagatggaaa agtcaaagaa gtcagtgata tagagacgat cgttttgtgg
    11581 attttgaaag acattaattc cctcaacaat tacaaaatca gcagctttga cactttgttt
    11641 cttttcgggt acgatgtcgt aaacttcatg agaatagaca ggaatatcta catcttgtcc
    11701 atttttgatg cggtccaaga agttgagaag agcttccata tcatagcttt caggaaatcc
    11761 tttacgattt aaaatcccct gctcaatcaa ggtttgattg ggatagagaa aaccatcagt
    11821 tgtaaccaac tcaaccgtag catctgtaaa cgtacgggac agtaggattt gaagtaggcg
    11881 actggttgtg gattttccaa cggcaacact cccagaaacc ccaataataa aaggttgaga
    11941 tttactttca cgttggagga aaattccttt tgaaaaggct aaatcttcct tagttcgctt
    12001 gtaaatctga atcagatgag ccaaggggag atagatatct gtaacgtctt ggagactgat
    12061 ttggtcatta aaactcttga tagattccaa ttcttcttct gtcaaaggag gtgttgtctt
    12121 tcgatgtaaa gattgccaag tctggcggct gattttttca aaatgtaaaa attcgttggt
    12181 catttgtttt cccctagata ttttgtctat cataccataa aaagctaaaa aaataaagcg
    12241 gtttcttgaa tgttgtaagt caatgatata taatataagt gatcaattta ttgatgaaat
    12301 aggagataga ttctactgat ttataagctt ataaaggggg ctttttagtt cacaacttat
    12361 aggaggtgta ctatgaaaat cttaaaacgt tacatattgg aactctgttt tattttaagt
    12421 tttgctttac cttttataaa aggaaccaat gcagataatg gtagatgctt tgtggaaacc
    12481 tattacggtt ttactttttt gatggaacat gctattgtaa cagctgtctt tatttgttcg
    12541 ttcttaattg ctttcttact aaaaaacgat ggacgaaatg gattgctgcg ggtagttatt
    12601 gctttttagt cctacggatt gcgacagagg gttatttctt ccacatgtca ctagaagatt
    12661 tgatacgact ttggacaagt ttggaaatcc tgacacaaac gtatcagttg ggcttttatc
    12721 taaacatttt gttaggaatt ttgttgataa taaagtattt taaggttaag caatagaaat
    12781 aataatctgc ctgattatag atgataaact ttttgttttt atctggactg tgatatttat
    12841 agttctaaat gatttattat ttataagtgt tgaaagagat tgaagaaaat ggcttcgtga
    12901 cttgctttct tcggtctttt tcgttttatt atcaatttgt aaacgattta caatttgagt
    12961 caaattatgg taaaatagtg tcatgagtaa aatgtactat gcagaaaatc ctgacgctgc
    13021 tcacgacatt catgagttga gagtggactt gttgggagaa aaaatgactt ttttgacaga
    13081 tgcgggtgtt tttagcaaga aaatggttga ctttggaagt caactcttgc tcaagtgtct
    13141 ggatgtcaac caaggagaga cagtcctaga tgtaggctgt ggttatggtc cattaggttt
    13201 gtccttggtc aaggtttacg gagttcaggc gaccatggtt gatattaaca ctcgtgccct
    13261 ggatttagct cagagaaatg ctgaaaaaaa taatgcaaaa gcgacgatat ttcaatctaa
    13321 tatttatgca agagttcaag ggcgatttga ccatgtcatt tccaatcctc ctatccgtgc
    13381 gggcaagcaa gtcgttcatg aaatcatcga gaaaagtaaa gatttcttgg aaattggtgg
    13441 cgatttgacc atcgtcatcc agaaaaaaca aggagctcca agtgccaagt ctaagatgga
    13501 agatgtgttt ggcaattgtg aaatccttaa aaaagacaag ggatactata tccttagaag
    13561 tgtgaaagaa tgagagcagt tgatttaatc caaaaaaaac gagacggtca agaactgact
    13621 tcaagtgaaa ttgaatggct gatagaaggc tatgtatcag gaactgttcc tgattatcag
    13681 atgtctgcct ttgctatggc tgtttatttt aaaggaatga cgactcgaga aatctctgat
    13741 ttaacgatga atatggttaa gactgggcaa gagtttgacc tgtcagccat tgatggtgtg
    13801 aaagttgaca agcattctac tggtggtgtc ggcgataagg taaccttgat tttagctcct
    13861 cttgttgcta gcttcggtgt gcctgtagca aaaatgagtg gtcgtggtct tggccataca
    13921 ggcggaacaa ttgataaatt ggagtccatt aagggctatc aagtagaacg tagtcaagag
    13981 gattttattc gtcaggttca ggatattgga gtatctgtca ttgggcaatc agaccagctg
    14041 gtcaaagcag ataagcttct ctatgccctt cgtgatgtga ccgcaactgt cgacatgatt
    14101 cctttgattg cgagttcggt gatgagcaag aaaattgcgg caggggcgga tgctattttg
    14161 ctagacgtga ctgtcggtga gggtgccttc atgaagacgg ttgatgaggc gcgtgagttg
    14221 gctcaaacta tggtagatct tggtaaggtt gttggacgga agacagtagc agtgattacg
    14281 gatatgagcc agcctttggg acgagcgatt ggaaatcgtc tggaaatcct tgaagcattg
    14341 gagattttgc aaggtcaagg acgtcaggat attacccact ttatttgtga attggctcaa
    14401 attatgcttg gtttggcaaa tgttaacaaa actgttgaag aagttcgcca acatcttgaa
    14461 aatggtcaag cactggctaa gtttgaggaa atggtgcaag cccaaggtgg agacttggaa
    14521 gacctctatc gtcctgtaaa tgtagctcat gtggtggaaa tccctgctca ggaaacgggt
    14581 gtcatttcag ctcttccagc tatggacttt ggtctttatg ccatgaggct gggtgctggt
    14641 cgtgcagtta agtctgatgt cttggactat gaaacaggaa ttgtttttga aaagaagatt
    14701 ggagactccg ttcaaaaggg tgaaattgtt gcaaaagtat acacaaatga aaaaattcca
    14761 cctcaactag ttacagattt ccaaaaatgt gttaaaataa gtgatgaagt gaaaaaaatc
    14821 cgtgaaattg tagaaatcat ctcctaaatg gagggaaaac cgaaatgaaa ttaaataaat
    14881 atatagatca tacgctttta aaacaagatg caaagaaaaa acaaattgat agtttgttgt
    14941 ctgaggctag agagtatgac tttgccagtg tttgcgttaa tccgacctgg gttgaacatg
    15001 ctaaaaaagg acttgaaggc acagatgtta aggtttgcac agtagtaggt ttccctttgg
    15061 gagcaacaac ttcagccgtg aaagcatttg agacaaaaga agctatccaa aatggtgcag
    15121 atgagattga tatggtgatc aatgttgggg ctctcaagtc aggtgatttg gccttggttg
    15181 agtcagatat tcgcgcagta gtggaagcaa gtggtgataa gttagtgaaa gtcattattg
    15241 aagcttgcct tctgacagac caagaaaaag ttgttgtttg ccaattgtcc caaaaagctg
    15301 gggctgactt tgtcaaaaca tctactggct tttcaactgg tggtgctacg atagcagatg
    15361 ttacattaat gcgtgaaaca gttggatctg atatgggtgt caaggccgcc ggtggagctc
    15421 gttcttatgc agatgctctt gcctttgtcg aagcaggtgc gacccgtatc ggaacgtcag
    15481 ctggggtagc tattttaaaa ggagaattgg cagatggcga ctactgagtt gattgaactg
    15541 gcaattgaaa ccagcaaaca tgcctatgtc ccctattctc actttcctat cggagcagtt
    15601 ttagtagcta aagacggaag tgtttacacg ggagtgaata tcgaaaatgc tagctatcct
    15661 ttgaccaatt gcggtgagag aacagcagtt tttaaggcta tatctgaagg ccaaagagaa
    15721 ttttcagaat tgattgtcta tggtcaaact gaaaaaccga tctcgccatg tggtgcttgt
    15781 cgccaagtga tggctgaatt ttttgaacaa gatctaaaag tgaccttagt cgcaaaagat
    15841 aaatcgacgg tcgagatgac ggtcggggaa ttacttccat actcttttac agacttaaac
    15901 tagtctgagt cgctctctga gtggcacggt ccttgtggcc aaccaatcca tacttgcaac
    15961 atcgttgcac atcttattta ggaggttcag taatgaacaa gaaacaatgg ctaggtcttg
    16021 gcctagttgc agtggcagca gttggacttg ctgcatgtgg taaccgctct tctcgtaacg
    16081 cagcttcatc ttctgatgtg aagacaaaag cagcaatcgt cactgatact ggtggtgttg
    16141 atgacaaatc attcaaccaa tcagcttggg aaggtttgca ggcttggggt aaagaacaca
    16201 atctttcaaa agataacggt ttcacttact tccaatcaac aagtgaagct gactacgcta
    16261 acaacttgca acaagcggct ggaagttaca acctaatctt cggtgttggt tttgcccttc
    16321 acaatgcagt tgaagaagca gctaaagaac acactgactt gaactatgtc ttgattgatg
    16381 atgtgattaa agaccaaaag aatgttgcga gcgtaacttt cgctgataat gagtcaggtt
    16441 accttgcagg tgtggctgca gcaaaaacaa ctaagacaaa acaagttggt tttgtaggtg
    16501 gtatcgaatc tgaagttatc tctcgttttg aagcaggatt caaggctggt gttgcgtcag
    16561 tagacccatc tatcaaagtc caagttgact acgctggttc atttggtgat gcggctaaag
    16621 gtaaaacaat tgcagccgca caatacgcag ccggtgcaga tattgtttac caagtagctg
    16681 gtggtacagg tgcaggtgtc tttgcagagg caaaatctct caacgaaagc cgtcctgaaa
    16741 atgaaaaagt ttgggttatc ggtgttgacc gtgaccaaga agcagaaggt aaatacactt
    16801 ctaaagatgg caaagaatca aactttgttc ttgtatctac tttgaaacaa gttggtacaa
    16861 ctgtaaaaga tattgctaac aaggcagaaa aaggagaatt ccctggcggt caagtgatcg
    16921 tttactcatt gaaggataaa ggggttgact tggcagtaac aaacctttca gaagaaggta
    16981 aaaaagctgt cgaagatgca aaagctaaaa tccttgatgg aagcgtaaaa gttcctgaaa
    17041 aataatggat ggaagtcatt tcttaggaag cggccaaggg ccgctttttt aagagttgag
    17101 acaaagtcat tttgtctcag taaagcttgc tactagacaa actagcaagt tttattgaaa
    17161 taaaataaga ctctgaaagg aagagcacat ggcacacgaa aatgtcattg agatgcgtga
    17221 tattaccaag gtgtttggtg gatttgttgc caacgacaaa atcaacttgc acctacgaaa
    17281 aggtgaaatt catgcacttt taggagaaaa tggggctggt aagtccacgc taatgaacat
    17341 gttagcaggc cttcttgaac caactagtgg tgaaattgcg gtcaacggtc aagttgtcaa
    17401 tctcgactcc ccatctaaag cagctagctt gggaatcggg atggttcacc agcactttat
    17461 gttggttgaa gccttcacag tggctgaaaa catcatttta ggtagtgaat tgactaaaaa
    17521 tggtgtgcta gatatcgctg gagctagcaa agaaatcaag gctctttctg aacgttatgg
    17581 cttagctgtt gacccttctg ccaaggtagc agatatctca gttggagccc aacaacgtgt
    17641 agaaatttta aaaacacttt atcggggggc tgatatcctt atctttgacg aaccaacggc
    17701 tgttttgact ccatcagaaa ttgatgagtt gatggctatt atgaaaaatc ttgtcaaaga
    17761 aggaaaatca attatcttga ttacccacaa attggatgaa attcgagcag tttctgaccg
    17821 tgttacagtt atccgtcgtg ggaaatcaat tgaaaccgtt gaaattgcag gggctaccaa
    17881 tgctgatttg gcggaaatga tggtaggacg ttctgtttcc tttaaaacag agaagcaagc
    17941 ctctaaacca aaagaagtgg ttttgtctat caaagatttg gtggtcaatg aaaaccgtgg
    18001 tgttccagct gttaaaaatc tgtccttgga tgttcgtgct ggagagattg ttggtattgc
    18061 ggggattgat ggaaatggtc agtctgaact gattcaagcc attacaggtc ttcgtaaggt
    18121 tgaatctggt agcattgagc taaaaggaga ttcaattgta ggcttgcacc cacgtcagat
    18181 tacagaacta agtgttgggc acgttccaga agaccgtcac cgtgatagct tgattttgga
    18241 aatgatgata tctgaaaata ttgcccttca aacctactat aaagaaccac atagtaaaaa
    18301 tggaattttg aattattcaa atattacttc ttatgctaaa aagctgatgg aagagtttga
    18361 tgttcgcgct gccagtgaat tagttcctgc agctgcactc tcaggaggaa atcaacaaaa
    18421 agcaattatt gctcgtgaaa ttgatcgaga tcctgatctc cttatcgtta gtcagccaac
    18481 tcgtgggttg gatgtcggtg ccattgagta tatccacaaa cgcttgattg aagagcgtga
    18541 taatggcaag gctgtccttg ttgtcagctt tgaattggat gagattttaa acgtctcaga
    18601 ccgtattgcc gttatccacg atggtaagat tcaaggtatt gtatcaccag aaacaaccaa
    18661 taaacaagaa cttggtgtct tgatggctgg tggaaacttg ggaaaggaga agagtgatgt
    18721 ctaaaaaatt acaacaaatt tcggttccct tgatttctgt attcctagga attttactcg
    18781 gagccattgt catgtggatc ttcggttatg atgctatttg gggctacgaa gaattgttct
    18841 atacagcctt tggcagtctg cgtgggattg gagaaatctt ccgtgctatg ggtcctctgg
    18901 tcttgattgg tcttggtttt gccgttgcca gtcgagctgg tttctttaac gtcggacttc
    18961 ctggtcaggc tttggcaggt tggattctca gtggttggtt tgccctgtcg catccagata
    19021 tgccccgtcc cttgatgatt ctagcaacca tcgtgattgc cttgattgct ggtgggattg
    19081 tcggagcgat tccaggtatt cttagggcct atctagggac gtcagaggtt attgtaacca
    19141 tcatgatgaa ctacattgtc ttgtatgtag ggaatgcctt tatccatgct ttccctaaag
    19201 acttcatgca aagtacagat tcgaccattc gtgttggggc taatgcaacc tatcagacac
    19261 cttggttggc tgagttgact ggtaactcac ggatgaatat tggtattttc tttgccatca
    19321 ttgccgttgc agttatttgg ttcatgctca agaaaacaac tcttggtttt gaaatccgtg
    19381 cagttggtct taatccacat gcttcagaat atgctggtat ttctgccaag cggactatta
    19441 tcctatctat gattatttca ggtgccttgg caggtcttgg tggagctgtt gaaggtttgg
    19501 gaaccttcca gaacgtctat gttcaaggtt cgtcattagc tatcggattt aacggaatgg
    19561 cggttagttt gcttgcggcc aactcaccaa ttggtatact ctttgcagcc ttcctatttg
    19621 gcgttctcca agttggggct cctggtatga atgcggcgca ggtaccatct gagcttgtca
    19681 gcattgtaac agcgtctatt atcttctttg tcagtgttca ttaccttatc gaacgctttg
    19741 tcaaaccgaa aaaacaagtt aaaggaggta agtaaagatg tctattataa ccttgctccc
    19801 cctcttggtg tcttctatgc tgatttactc agcacctctc atctttacaa gtatcggtgg
    19861 tgttttctct gaacgtggtg gtgtggtaaa cgttggcctt gaaggaatta tggttatggg
    19921 tgccttttct ggagttgtct ttaaccttga atttgcagaa caatttggag cagcaactcc
    19981 atggctatcc ttgcttgtag caggattggt tggtagtgtt ttctctatca tccacgcagc
    20041 agcgacggtt catttccgtg cagaccatgt tgtcagcggt acggtattga acttgatggc
    20101 gcctgccttg gctgttttct tagttaaagt tctttataac aaaggacaaa ccgacaacct
    20161 aagtcaaact tttggacgct ttgatttccc agtcttggca aatatcccag tgattggtga
    20221 tatcttcttc aagtcaacta gtctacttgg ttatctggcg attgccttct cattccttgc
    20281 ttggtttatt ctctttaaga ctcaatttgg tcttcgtctc cgctctgtcg gtgaacatcc
    20341 tcaagcagcg gataccttgg gaatcaacgt ctacaagatg agatatttag gggttattat
    20401 ttcaggtttt ctaggtggaa ttggcggagc gatttatgcg caatcaatct cagttaactt
    20461 ctcagtgaca actattgttg gacctggatt tatcgccctt gctgcgatga tctttgggaa
    20521 atggaatcca atcggtgcta tgctttctag tctcttcttt ggactttcac aaagtttggc
    20581 tgttatcggt tctcaattgc cgttcctaca aggagtgcca gcggtttatc ttcaaattgc
    20641 accttatgtt ttgacaattc ttgtcttagc agccttcttt ggaaaagcag tcgcaccaaa
    20701 agcagatggt atcaactaca tcaaatcaaa ataagcatac aaaaaaacgt cagtccaatg
    20761 a
//
LOCUS       DAVLTT010000034        20124 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLTT010000034 DAVLTT010000000
VERSION     DAVLTT010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.034"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            244..420
                     /locus_tag="VYN15_001346"
                     /pseudo
     CDS             244..420
                     /locus_tag="VYN15_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            793..939
                     /locus_tag="VYN15_001347"
     CDS             793..939
                     /locus_tag="VYN15_001347"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1452657.1"
                     /translation="MKAQAIVTSQGRIVSLDIAVNYCHDMKLFKMSRRNIGQAGKILA
                     DSGY"
     gene            946..1182
                     /locus_tag="VYN15_001348"
     CDS             946..1182
                     /locus_tag="VYN15_001348"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1452658.1"
                     /translation="MKIYPQAQTPRKSSKLKPLTAEDKAYNHALSKERSKVENIFAKV
                     KTFKMFSTIYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(1345..1596)
                     /locus_tag="VYN15_001349"
     CDS             complement(1345..1596)
                     /locus_tag="VYN15_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452659.1"
                     /translation="MPKTKTLAELADVILWSFDFVNDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYIENVYLDSLSVKQKFKFIFDFGDEWRFEC"
     gene            complement(1886..3766)
                     /locus_tag="VYN15_001350"
     CDS             complement(1886..3766)
                     /locus_tag="VYN15_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1452660.1"
                     /translation="MVRFIGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(3760..4629)
                     /locus_tag="VYN15_001351"
     CDS             complement(3760..4629)
                     /locus_tag="VYN15_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1452661.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALISYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(4713..7358)
                     /locus_tag="VYN15_001352"
     CDS             complement(4713..7358)
                     /locus_tag="VYN15_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV1452662.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEVTIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(7449..8729)
                     /locus_tag="VYN15_001353"
     CDS             complement(7449..8729)
                     /locus_tag="VYN15_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV1452663.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            8900..10984
                     /locus_tag="VYN15_001354"
     CDS             8900..10984
                     /locus_tag="VYN15_001354"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV1452664.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            complement(11024..12703)
                     /locus_tag="VYN15_001355"
     CDS             complement(11024..12703)
                     /locus_tag="VYN15_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV1452665.1"
                     /translation="MKKIKPHRPLPSQTQLAYLGDELAAFIHFGPNTFYNQEWGTGQE
                     DPERFNPTQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFDCRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            13459..14688
                     /gene="arcA"
                     /locus_tag="VYN15_001356"
     CDS             13459..14688
                     /gene="arcA"
                     /locus_tag="VYN15_001356"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV1452666.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            14746..15762
                     /gene="argF"
                     /locus_tag="VYN15_001357"
     CDS             14746..15762
                     /gene="argF"
                     /locus_tag="VYN15_001357"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV1452667.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            15927..16874
                     /gene="arcC"
                     /locus_tag="VYN15_001358"
     CDS             15927..16874
                     /gene="arcC"
                     /locus_tag="VYN15_001358"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV1452668.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            17083..18594
                     /locus_tag="VYN15_001359"
     CDS             17083..18594
                     /locus_tag="VYN15_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV1452669.1"
                     /translation="MSEKAKKGFKMPSSQTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALAIGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            18616..19947
                     /locus_tag="VYN15_001360"
     CDS             18616..19947
                     /locus_tag="VYN15_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV1452670.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            20040..>20124
                     /locus_tag="VYN15_001361"
     CDS             20040..>20124
                     /locus_tag="VYN15_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1452671.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRF"
BASE COUNT         5763 a         4502 c         4120 g         5739 t
ORIGIN      
        1 gtagaataga gtagtacatt ttataaattg tcatctctcc ataaacacag tatatcattt
       61 ttaaatttta agtcaaggaa aattaaccca ctttaatttc ttttttaacc cgtgttaaaa
      121 aagaaattaa agtgggttaa aaaataaatt aactgagtaa aaactctcga aattcaattc
      181 gctatattat cactcaactt gaacaaatac cagaaccaca aaaaacagat gtaaaggaaa
      241 aatatggact taaaatttga aggggttgat ttagaataca aaaaagctaa aaacaatctt
      301 ccagagtctt tctgggaaac ctactcagca tttgcaaata caaatggcgg gaaaataatt
      361 ctcgggatag atgaaaaaaa cattgacacc taccaaagag tcaatagact ccctgcgaaa
      421 caaaattatg aagcaagtaa acaactaacc gatgcacgat ttaagcgtct tgttggtgtt
      481 caacgcacga cttttgaaga gatgttagct gtattaaaaa cagcttatca acttaaacac
      541 gcaaaaggtg gacgaaaacc taaattaagc ctagaagacc ttcttatggc cactcttcaa
      601 tatgtgcgag aataccgcac ttatgaacaa attgcggctg attttggtat tcacgaaagc
      661 aacttaatcc gtcggagcta atgggttgaa gtaactcttg ttcaaaggtg gtgttacgat
      721 ttcaagaact cctctcagtt ctgaggacac ggtaatgatt gatgtgacgg aagtaaaaag
      781 aaatgccacg ctatgaaggc tcaggcgatt gtcacaagtc aagggagaat tgtttctttg
      841 gatatcgctg tgaactattg tcatgatatg aagttgttca aaatgagtcg cagaaatatc
      901 ggacaagctg gtaaaatctt ggctgacagt ggttattaag gactcatgaa gatatatcct
      961 caagcacaaa ctccacgtaa atccagcaaa ctcaagccgc taacagctga agataaagcc
     1021 tataaccatg cgctatctaa ggagagaagc aaggttgaga acatctttgc caaagtaaaa
     1081 acgtttaaaa tgttttcaac aatctatcga aatcatcgta aacgcttcgg attacgaatg
     1141 aatttgattg ctggtattat caatcatgaa ctaggattct agttttgcag gaagtctatt
     1201 gaaatactaa gcctacacag actgatttca attttaccat tcttcatagt caaaaccatc
     1261 ataatctgga tattgttctg gcaacgttcc aaccgaacgt acgagataag cttcttcgtc
     1321 ctctgtctcg atttctctca gcacttagca ttcaaaacgc cattcatcac cgaagtcgaa
     1381 aataaactta aatttttgtt tgacacttag gctatccaga tagacatttt ctatgtaacg
     1441 ttcttcaaca tcgtcactaa caaagctaag aaagtaagaa tctgcatgac tccactcaac
     1501 attatccatg aaaaatgcat gagcatgatc atttacaaaa tcgaaactcc ataaaatcac
     1561 atctgctagt tccgctaacg tttttgtttt tggaatctat atatgtcggt agcaaccttt
     1621 tttaatttga cggaaatgat ccaagcttct acagatgctg gcttttcagc ttctatttct
     1681 tgttttacta attttaactg tagcatttga aaccagatac ttcttctgtt tcacgcgaaa
     1741 caccctgcgc caagcaaggt gttcttgttt ttatactcaa tgaaaatcaa agagcaaact
     1801 aggaagctag ctgcaggttg ctcaaaacac tgttttgagg ttgcagatgg aagctgacgt
     1861 ggtttgaaga gattttcgaa gagtattaag tcgtataaat cgtcgacgct gtcgcaatgg
     1921 tatgccactg gttggctgta gttgctgcga aatccttgtc tgcgtagaag tcagtaaatg
     1981 gtaggatttc aacttccagc tcgtcgatgc ggtcaagctg accagccaga taaacctcga
     2041 tacggctttc tgctcgtttg atgcgttgca agagtccgcc catacggatg tcaactgtat
     2101 ccaaaccaaa gaccttgttt tctttcagcc attggtggct aaagagggca tggaagtctt
     2161 caatttggct tctaagttct ggtaattctt gtctggcgat ttgttgtaaa ctttctttat
     2221 catccgcttg gtaggcctga cgaatgcgtc gtcccacatc tactttgcta cttaaaatag
     2281 cattcaactg ggcctgagtt tcaaagagat aagcatagtt tccagctttt tctttaatgt
     2341 tagcaagcgt ctcagcagcc tgagcgaagt gcggtttgtc ctgttcaggt gtcatgtgtt
     2401 gatcaagaat cggacaaaga atatcctgat aaaaaacata gcggttggga ttgataccgc
     2461 tgagattgcc tggtaggtct ggtaagaggt tggcaaggtc aatctgcata aaatcctcaa
     2521 ccgttagacc agtattggtc ttgaagtgcg cagacaaact atctaggtca ttgcgatagc
     2581 tgagttctgc ccagatttgc aagcttggta ggatagagaa ctgggcagtt tcaccaccat
     2641 tgtctcccca accagttacg atgacttctt taatctgatt ggcacggcag gctttattag
     2701 cctcgatagc cactagacgg ctaaaatgat tgtgaggtgt aaagccaatc cacttccaag
     2761 ctccccctgc aaatgcaagg tcatggctaa tcttgtgatg attgcggaaa ttacggttgt
     2821 atttttcctc gctatcctga taataatccc agtaaaccag agtcacacgg tctttgagac
     2881 ggtctaggta gacacgagtt tcctctggaa tttccacatc acggtcgtac tggccatccg
     2941 ctgacatgag tttgaagaac atatcactcc acatctggca gtggaaacca tatttgtcag
     3001 caatatccag cacgcgctcc aagtgttggc acatgaggag actacgatcc acaacaccgt
     3061 tcagaatcag gtagcgtccc aaaccaacca agtgggcttc gtccatcccg atattgacct
     3121 tgcgagtctt cagtttagac aacgtggcaa acatgccatc aatcaggtca taaacctttt
     3181 cttcgccaat gagaagaatg tcctctacat cacggagctc ctgcacttcc ttgacacccc
     3241 atttgacaaa ggctgacagg tgggccaagg tctggatgca tggtacaaag gtcatgtcaa
     3301 actgttgagc ataggcttcg atttcctgca actcctctgc tgaataagct ccacggaaat
     3361 agccaaagta aggctgccct tcaatctggt aagtgtcttc catgtaaagc tcaaaggttg
     3421 agtagcccat gagagccaag acctcaatca tctgcttggc agaagccaca ttcagcaccg
     3481 catttcgaga acagtcaacc atgtaagcca aatcttcgta agctgcttgt tcctcaatct
     3541 ctactttatc agcttctgct agaactgtta ccaacaagga caaggcacga taaagttggt
     3601 gaggtttgcg ataggtcaat tgatagtgac cttcctcacc ctcgatagag atagatgctt
     3661 ggtcagactg agtgacagcc acttccacat ctggtagaga aatgtgacct tttaaaacct
     3721 caatagcttg cgtttgtttg agactaagtc ctataaatct taccactgct tttcctcctg
     3781 tagccagttg acaagagcac cgtagagatt ggcatctgcg tgataggtgc aggcctggat
     3841 aactggtgcg accgtgtatt cttcgtaggc atcgacaaag tcttcaacag ccttcttaac
     3901 accttggata aaatctggat tttgactgat agagccaccc agactgatga catctggatc
     3961 gatgagatac tggatattga gcaagccttg cgtcaaattg cggttcatgc gctcaatggc
     4021 ttcttgacaa agagcattac cagctgcggc ctcttggtaa atcttgcgac cgtcccaatc
     4081 agtatgacca gatttttcaa tcacgtatcg taccatattc ccagttgatg ctagttgcga
     4141 ccagttatta agtttttcag caggggcaag ggttgtcatg tagccaaatt ctccacccag
     4201 accgtggcga cctcgatgaa gtctaccatt gataatcatg gctccgccaa tccctgtccc
     4261 aatcacgaca caggctgcat tttcaagctc tggatgagct agtagttcac tgagtccaac
     4321 gcagttggca tcattttcta aatggacagg tagctgataa gagataagcg cctcatacca
     4381 agaaaagcca tggatgtagg gcaccgcact gaagccatca atcacacctg tctcttgatt
     4441 gactgcacct ggaacactca tagcaatccc actgtaatcc tgttctgaca agcgttgatc
     4501 tagccacgct agtaaatcct ccaagttttc aggcgttgaa atacttgtct tatccagtat
     4561 tttcccatca ggagtcagac tggcaaactt aatcccagtc cctccgatat caatcgttgc
     4621 aatggtcatt gtttttacca taaaaagggg cgaatcagca gttagttctt actttttcgc
     4681 ccctcctttc ttttgatgtt tactttttga aattaaattt cttctttttt gatgaattct
     4741 gtacgaatct cttgtggagc caatagtcct gaatgaactg gatatggtcg ctcaagtaag
     4801 tcaagaatgg tttgttgatg ttctgatatg cgcacatttt cttgactcat attatagtaa
     4861 cggaggacat agccttcttc attttccgcc actttaaagg ctgttggaca aacttgcggt
     4921 atgctgagaa cagaatggct caagaggcta ccagtcgcaa ccacgcttcc ttcctgtcta
     4981 gcaagctgaa ggctggtaaa cggtgtctgc aaggctttgg cacgacgata ggctgagaag
     5041 cgttcttggg cttggtggca ttcaatcgca aattcgactt caaactcacg caagcattgt
     5101 gcttctggcg ttgggaagta gccccagtca cctagctcac ctgatgcacg caaaatggtc
     5161 acggcaatgg tgttatcccc aaggatttcg tattcattca atcccttgtt ggatacagtc
     5221 accccttttt catcgtcata cagactgaca aaagcttgtt ggtgttgagg attttcagga
     5281 ttttcccatg aagcagctgg tttgtttggt cgtgtcacca cctcatagat actttcagaa
     5341 tcattgcttg gacgcgtgtt atgagtcttg accaagagac ggatacggtg atccttggca
     5401 gtgttagtaa agcgagtctt gaagcggatt tgtggattgt caacaaagac aatcaactca
     5461 gtttccagag gaatgtttgt caattcttct gaccgtccag cctcacgctt cataaactcg
     5521 atgatacctt gttgctcttc ttctagcttt tcatccgcac tgacaggcac ggtcaattca
     5581 tgtttgagca agattttagc atagcgatct gtgttttcca agacctcgtg gcccttaagc
     5641 tctgcaaaga ttggctctgt tccttttggt tggaaataga tatactcgtt tccgatgtca
     5701 ccccggtctt cgaagcggat aaagtcttca taggcttcgt gagttgtctt gtcatagact
     5761 gtgatgttgt catccacact caccgttacg aatggtgtat caatcactcc gttttggtaa
     5821 ataccctcac ggtgttcttg ttctccttcc agcaattgga aggttgtcca agaaagcggt
     5881 gctaggtgaa ctggaatggt cacgcgcact tgtcgagcaa tacgagcttg gcggaactta
     5941 tcttttggta aatcgtattc aaaattagct ccgaggtctt cgattgtaac ctctacagga
     6001 cgaccatcca agtcctccac acggtaactt ggcaagataa gagcagccat ctttttgtag
     6061 ccttctgttg ggtgcaattc cttgaaatca caagtcgcca catcaatcac tgtgctgaca
     6121 gtatcgacct tatcatgcaa gcctgtgtta atgacagtaa agagatagtc actttgagcc
     6181 ttatccgtag caattttacc cttccactcg ttgagcaaat tacttttaac aaagtttcct
     6241 acttggttga ccttggcaaa acgcgtttcc atctcgcggt gaacttcgtc cacgctacag
     6301 ccacagatac tatcatgtgg cgcattctgc aaaagtgttt tccaagcata ggtcaactgg
     6361 tccttgtggt tgtgtccacc agtgataata gtcaagggtt ctaccacttg ctctaggagg
     6421 ttgctatttt cttggaaggc ttgttttagg taaatgcggg atgaagaagt gttggcaagt
     6481 gtgtaccagc catctgtttc ctgactggtc aactcgcctg taacagttga taagtgttca
     6541 ggaagcgcac cttctacagc ttgaacatat tcatcaaaag aactatgaac aaagattaca
     6601 tccgggaaga gttcatttgc cacacgaatg gcttcgctca gatttttctg tacaggctgg
     6661 tggtcacagc cgttcatcat caaccattgg ttggtcgaag cgtaggcacg cacatctgac
     6721 aatttttgtt tccagaaggt caaggcctca tctttgtcaa ctgggatttc attcccatta
     6781 ctgtaccagt tggcaaagag aatacctaaa acacgactac catccacacc ctgccagtac
     6841 atttctgaaa actgggatgt aaaccgctca tcttcaagga cttggttgtc aaatccaatc
     6901 ggcttcacac cacgaccaaa ggctgccacg tgaatacctg atttttgaag gatttgagga
     6961 gcttgtccca tatttccaaa ggtatctgga aagtagccaa tctgggttga tttaccccat
     7021 ttggcagctt cttgttgacc aatcaaggta ttgcggacat tggcttcact ggagatcaag
     7081 tagtcatcct gcaagatgta aaagggacca attttaagtt tgccctcgtc aatgtagcgt
     7141 tggaccttgt cgcgattttc agggcgaatt tgtaagtagt catcaaggac aatagtttgt
     7201 ccatccaagt ggaaactctt gaactcaggg tcattttcaa agagatcaaa gagattgtca
     7261 aacaattcca ccaactgcat acgatggctt tcaaaaggca agtaccactc acgatcccag
     7321 tgactatgtg agataatatg tacaacaaca ttttccatga agtaaaacct cattctaaat
     7381 ttaaatttta acgttttaaa tgtaaacttg tgattctgat aagaatcggt tgagctaaag
     7441 cgagcccctt agcggatatc caagtaatcc aagaccaact cacagaacat catgttagcc
     7501 caggagaacc attcacgaga gtagagggtc ggatcatcta cgtggaagct ttcgtgcatg
     7561 acacctgtac caccatcgca ggcaaccagc tgatccagca agaatttttt ctctgcctta
     7621 tctcttgttg tcaatccttg gatagaaagg gcgattggcc agatatagcg atagaaggta
     7681 tgagaacttc cgagaccgct agcgtattct ccttggtaga agtatggatt ttcagagctc
     7741 agaatggtac ggcgagtggc ttgatacact tcatcatcga tcgaacagta gcccagatag
     7801 ggcgcagcta gtagacttgg tacatttgga tcatccatga tgctggcatt tcctaggcca
     7861 tctacttcaa aagcgtaaat cttttcgccc ttgctgttgg tggtgtaagc gtagttttcg
     7921 attccttctt ggatttcatc ctgaagacgc ttggcatcag caataacact ctggctatca
     7981 gctaggttta atgctgcgaa gatttcttgc acataaccca agactactac agcaaacata
     8041 tttgacggaa tcaagtaact atactggcaa cagtcatcac tcggacgaaa ggctgaccaa
     8101 gtcatacctg tcactgcaaa gtcaggtcca aagccatcat ttaccaaggt gtcttcctta
     8161 cggtccgtat ctcggacaaa acgataagga gagttcttgt ggtcttgttc aactgtccat
     8221 agatggagaa tttccttagt cgctgcgaca aaagtttcat caaactgact agtctcgcca
     8281 gtctctttcc agaggagata agccaactgc aaaggatagc aaagcgaatc cacctcatac
     8341 ttgcgctccc agatccagcc gttaaggtct gtgtggtcag tctcgtggtg ccctttccag
     8401 ttctcctcaa tgttgaagga gttagcatag ggatccttga gtaccaaggt catctgacgt
     8461 ttgaccaaac ctgcaatggt ctgacgcagg agggcatctc ttttagctac atgaaggtag
     8521 ggtctgagtt gggctgtcga atctcgaagc cacatggcag gaatatcccc agtcaagaca
     8581 aaagttgaac catcttctaa gatttcaacc gtattgtcca aggtatcggt gtagcaacgc
     8641 tcgaaaacat ccacccactc tggatggtcc ttagcccgct ctgctacttc atctagccat
     8701 tctctaacaa tttctttcga ataaatcatc gtgcaatttc ctctttcaaa caagtttcat
     8761 tttcagtata tagcttttga gacagaaaat acatacacaa atgatagtca tttttctaca
     8821 aaatagttat ttttgaaact ccttttctaa aggccctctt tttctgatat aatgtagaaa
     8881 aacagctaaa ggaaagacta tgaaaccact acttgaaacc atcgataccc gctttggtac
     8941 tgctagcaaa catgccttct ctcggggaaa taccctgcca tacacaggcg tgccttttgg
     9001 gatgaattat tttgtgcccc agaccagtga ccaggatgga tcttggtttt ttgatccgca
     9061 tctgcctatc tttcagggga ttcgattaac tcaccagccc agtccttgga ttggggacta
     9121 ctcttggctc cttctgacac ctgtcaccag tcaactgggg ggagacagcc tctttcaccg
     9181 ccagtcttct tatgatatag ataaagcttg cttccagcct cactatttga agctcttttc
     9241 cctgcgctat caaattgaaa cccagctcac accgacttgc tatggtgctt ctattcgttt
     9301 gaagcaaaag caaggcaaag ccctctccct ctatcttcac gcagcagatg aactgaccgt
     9361 agagcaagta gataagcgga ctcttgccct gcgacaagaa ggtaaaactg aaactaacaa
     9421 aaattcgcta acgatgttca ctgccctgca aatgaacacg gatattcttg ctatcagcca
     9481 agaagctggg gactggcgaa ttgacttagc aagtagtcaa accgagatgc aactagccac
     9541 ttctttcatc tctccttctc aagctctaat caatctacct caagaagatt ttgatagctg
     9601 taaaacaagt gcccaagcgg attgggaaaa tctcctccat cgttttgaca ttatagagac
     9661 aggagaggct gaccgaacct tctttgacca ctgcctctac agactcttcc tcttcccaca
     9721 gactttttat gaggttgatg agtcagggaa agccatccac atggatctgg ctactggtac
     9781 tgtcaagcct ggtgtcctct ttagcaacaa tggtttctgg gataccttcc gcaccacctt
     9841 ccccctcttt gcccttatca taccggagca ctatcaacgc tttttagaag gtttcctcaa
     9901 tagctaccgc gatactggtt tccttccaaa atggctggct ccagatgaac ggggtatgat
     9961 gccaggtaca ctgctagatg gcattatcgc agatagcgcc tgtaaggaca tggcccccga
    10021 cctagaagga gaactcttcc aagccatgct cgaaacagcc agcaaagccg accctctcgg
    10081 catcaatggc cgccacggac tagcccaata ccaagaacta ggttacctct ctaccgacca
    10141 ccacgaaagt gttagccata ctctagacta tgcctatagt gacttttgta tcgccagctg
    10201 tgccaaaaaa ctagagaaca tagaaatcgc tgaaacctac aaggctgctt cacaaaatta
    10261 ccgccagcta tttgacgctg agacaggtta catgcgagca cgagacaatc aaggaaactt
    10321 tcaccctgac ttctctcctt atagttgggg gcgagactac gctgaatgct ctgccattca
    10381 agctacttta ggcgttctcc acgacatccc tggcttaatc caactgatgg gtggaaaaga
    10441 aacctttagc aactatcttt tgaaagcctg tcaagatgct cccctctttg aaacaacagg
    10501 ctatggttac gaaattcacg aaatgagcga gatggctact gctccttttg gacaaatagc
    10561 catttccaac cagcctagtt tccacattcc ttatctcttc cgctacagcg attaccctga
    10621 ctacactgcc cttcttatca agacgctccg tcagaaagct tttcacccaa gttgggaagc
    10681 ctatcctgga gatgaagaca atggtagtct ctctgcttgg tacatctggt cagctctcgg
    10741 attttatcca acctgtccag gaaaaccaag ctatgatctc ggaatccctc tctttgacca
    10801 tctacgagtc tacctagcta aagaaaataa atggctagat attcatactg agcaaaacca
    10861 cagccatttt aactttgtca aagaatgccg actggacaaa acactcgtat caactattca
    10921 acaccaagac ctcctaaaag ctgaacaact aactttcacc ctcagctggc taccaaatca
    10981 ctaataacca aaagaacctt tgcatcgcgc aaaggttctt cttttatgaa acttggactt
    11041 gaagttgatc cacaagctga ccatccaccg ttaggttcag atagaaatcc aaggttttat
    11101 ctcctgcgaa atacaaggtt ggtagcgtca gccttttttc agtctcacca gcttgaaacg
    11161 caaggacata aatctcgtcc tgataggcga caccatggac acctgtcccc ggttgaatcg
    11221 aaatcttagc ctctaaagag gagctacttt cactacgttc aatcctaaaa tgaagagtct
    11281 ctccctttgc cacagctagg cttttttctg caaatgctag ttcctgaaca acttcttttt
    11341 ttgataaccc aggagtttta taaagggaaa tcttggtcaa tacagggata gattgtgcct
    11401 cggtaatcat cacgcgcacc ttttgtgcct ctactagcgg acctcgcaag aggcgcttat
    11461 gaccaactgt gaagcccctg ccaaactcct gccagacacc atccacctct acttgcacat
    11521 gaaaagcagc gattcgttgc cctagcttca aatcttctct taactcaatt acatcaaaag
    11581 ttttaggaga acctaaatcg agttctaact ggatgggcaa gtctgcatcg cttgcccaag
    11641 agctggtctc aaggccgtct gtcaaatggc gacaatcaaa gtctgcggaa agagctggac
    11701 cagatacctc agctcccaga gccaaatctt ctttatagag ctcattgcga taggtcgcaa
    11761 attcataaag tcgttcaata tcctttgcat caaagagccc agcttgattc ggcggaatat
    11821 taagcaagag tggagttcct cgccctactg agtgaaagta gatttcgacc aactcctcga
    11881 gagacttagg atcctgatcc tcatggtaga accagcctgg acggatggaa acatctgcct
    11941 ctccgattga aaaaatcgtg cccgagggat ccccgtgctg aagatagttc agctctgctt
    12001 ctgttcctag tttatcaaga ttcacctttt gccacagtgg atcacctgca taccctcgtt
    12061 cattgccaat ccagcggata ctggtgcctt ctgttgaaaa aatcaagcaa tcgccctgca
    12121 ggtcacgaat ggtttcaaac catttttcaa attcataatt aaccttttgc gcgccctctc
    12181 ctctggcacc atccatccaa acctcagcga acttaccagc attcccatag ttaggatttg
    12241 ataagatttc cttcagctga gccagataat aggcattgta gtccgcttct cggtccacat
    12301 gatagagggg actatgggca tcccacggtg acaggtagac ccccatatcc atatcaaact
    12361 ctgtggcagc ttgggatact tcaaggagca agtcgccctt tcctctcctc caaggactga
    12421 ccttaaccga ataatctgtg tgagctgtcg gataaaggac aaagccatcg tggtgcttga
    12481 ccaccaaaat caactttttg aagcccgttt ccttgagcac gcgaacccac tcacgtgcgt
    12541 ctaactgtgt cgggttaaag cgttcaggat cctcctgacc tgttccccat tcctgattat
    12601 aaaaagtatt aggtccaaaa tggataaagg ctgctagttc atctcccaga taagctagct
    12661 gagtctgact tggtaacggt ctatgcggtt tgattttctt catcgttata tatctccttc
    12721 ttttgcaact tctcttgttc acaaggttat ccacaggttg tggataataa accatgatct
    12781 aacagccagc tctttccaac tccaactggt aggctcagga tttttctcct caatattccc
    12841 tcttcaaaca gctctgtcat atggttctgc taacacctct cagaatgcta ctctccataa
    12901 ttattctcag gcttctttca ggtcattgtg tgaagaccat tcactctcca gacttttcca
    12961 cagattgtga ataagtgatt attctaaact atcacctcgt cgactataac aaaaaataaa
    13021 aagagggtca ataagataat tatctcttcc taaatactca gaaaagattc tataatttgt
    13081 acaattgaac aagaaatgct tctccaaaat ctatcttcaa aagaatgttg catcttttta
    13141 tcctttcaca caaacatttc tctttataca gatccaagtg ataaccagat gataattgga
    13201 cactttttag tcatttgtat attttttgaa aaatttttta aaaaaatttt atatcctctt
    13261 taatagaagt ttatgcattt gtatctatgt attctatcct atgttatgta taataacata
    13321 aaattgtgct aaacatcata atttatatta ttttccgaga aattatagcc attgacatta
    13381 cctaggaatt gcgttataac atacatgtaa gcggtaccca aaatggtgcc aagtcaaaat
    13441 ttttaaggag gaaaatacat gtcttctcat ccaattcagg tcttctcaga aattgggaaa
    13501 ctgaaaaaag ttatgttgca ccgtccaggc aaggagttag aaaacttgtt gccggactat
    13561 cttgaaaggc ttctttttga tgatattcct ttcttggaag atgctcaaaa agaacatgat
    13621 gcatttgccc aagctcttcg cgatgaagga attgaggttc tctacctaga acaactcgct
    13681 gctgaatcat tgacctctcc agaaatccgc gatcaattta tcgaggaata cttagacgaa
    13741 gccaacatcc gtgatcgtca aaccaaggtt gctattcgtg aattgcttca cggcatcaag
    13801 gacaaccaag aattggttga aaaaacaatg gctgggattc aaaaagttga attgccagaa
    13861 attcctgacg aagctaaaga tctaactgac ttagttgaat cagattatcc atttgcaatt
    13921 gacccgatgc caaacctcta tttcactcgc gacccatttg caacaattgg aaacgccgta
    13981 tcgcttaacc acatgtttgc agacactcgt aaccgtgaaa cactctacgg taagtatatc
    14041 ttcaaatacc acccaatcta tggcggaaaa gtggatttgg tctacaaccg tgaagaagat
    14101 acgcgtatcg aaggtggaga cgagttagtt ctttctaaag acgtccttgc agtaggtatc
    14161 tctcaacgta cagacgcagc ttctatcgaa aaacttttgg tcaacatctt caagaaaaat
    14221 gttggcttca agaaagtttt ggcctttgaa tttgctaaca accgtaaatt catgcacttg
    14281 gatactgtct tcactatggt agactatgac aagttcacta ttcacccaga aatcgaaggc
    14341 gaccttcacg tttactcagt tacttacgaa aacgaaaaac ttaaaattgt tgaagagaaa
    14401 ggtgacttag ctgaacttct tgctcaaaac cttggtgtag aaaaagttca tttgattcgt
    14461 tgcggtggtg gcaatatcgt agcagctgcg cgtgaacaat ggaacgacgg ttctaacact
    14521 ttgaccatcg cacctggtgt ggtagttgtt tatgaccgca ataccgtgac caataagatt
    14581 ttggaagaat acgggcttcg cttgattaag attcgcggaa gtgaattggt tcggggccgt
    14641 ggtggacctc gttgtatgtc tatgccattt gaacgtgaag aagtgtaatc gctgttcggc
    14701 attcgtcaat agaaaatgta aaaaatagaa agaggaaata ataaaatgac aaattcagta
    14761 ttccaaggac gcagcttctt agcagaaaaa gactttaccc gtgcagagtt agaatacctt
    14821 attggtcttt cagctcactt gaaagatttg aaaaaacgca atattcaaca ccactacctt
    14881 gctggcaaga atatcgctct cctatttgaa aaaacatcta ctcgtactcg tgcagccttt
    14941 acaactgcgg ctatcgacct tggtgctcac ccagaatacc tcggagcaaa tgatattcag
    15001 ttgggtaaaa aagaatctac tgaagatact gctaaagtat tgggacgtat gtttgacggg
    15061 attgaattcc gcggattcag ccaacgtatg gttgaagaat tggcagaatt ctcaggcgtt
    15121 ccagtatgga acggtctaac tgacgaatgg cacccaactc aaatgctcgc tgactacttg
    15181 actgttcaag aaaacttcgg tcgcttggaa ggcttgacat tggtatactg tggtgatgga
    15241 cgtaacaacg ttgccaacag cttgctcgta acaggtgcta tccttggtgt caatgttcac
    15301 atcttctcac caaaagaact cttcccagaa aaagaaatcg ttgaattggc agaaggattt
    15361 gctaaagaaa gtggcgcaca tgttctcatc actgaagatg ctgatgaagc agttaaagat
    15421 gcagacgttc tttacacaga cgtttgggta tcaatgggtg aagaagacaa attcgcagaa
    15481 cgtgtagctc ttcttaaacc ttaccaagtc aatatggact tagttaaaaa agcaggcaat
    15541 gaaaacttga tcttcctaca ctgcttgcca gcattccacg atactcacac tgtttatggt
    15601 aaagacgttg ctgaaaaatt tggtgtagaa gaaatggaag taacagacga agtcttccgc
    15661 agcaagtacg ctcgccactt cgatcaagca gaaaaccgta tgcacactat caaagctgtt
    15721 atggctgcta cacttggtaa cctttatatt cctaaagtat aattttagat aataaaccgt
    15781 ctaccaacag ctatgagggc tgcgactaat agctttagtc cggtcctctt ttatgtaatg
    15841 gtaatctatt atttcttata aaatatgtga aaaatcatta aattgaaatc taaacgcatt
    15901 ctattgagtg tgataaagga gaatttatgg caaatcgtaa aattgtagta gctttgggag
    15961 gaaatgcgat tctttcttct gacccatcag caaaggctca acaagaagct ttagttgaaa
    16021 cagctaagca tcttgtaaaa ttgattaaaa atggagatga tctgattatc actcacggta
    16081 atggacctca agttgggaat ctcttgctcc aacatttggc atcagactct gaaaagaacc
    16141 ctgccttccc actcgactca cttgtcgcta tgacagaagg tagcatcggt ttctggttga
    16201 aaaatgcttt gcaaaatgct ctcttggatg aaggcatcga aaaaaatgtt gcctctgttg
    16261 taacgcaagt tgtcgtagat aaaaatgatc cagcttttgt taacttgagt aaaccaatcg
    16321 gtcctttcta ttcagaagaa gaagcaaaag cagaagccga aaagagcgga gcgactttca
    16381 aggaagatgc tggccgtggc tggcgtaagg tcgttgcctc accaaaacct gttgacatca
    16441 aagaaattga aaccatccgt actcttttaa ataatggtca agtcgtcgta gctgcaggtg
    16501 gtggcggtat tcccgtcgtc aaagaaaaca atggacattt gactggtgtc gaagcggtta
    16561 ttgataaaga cttcgcttcc caacgtttgg cagaattggt tgatgcagac ctcttcatcg
    16621 ttttgacagg tgtagattat gtatttgtta actacaacaa gccaaaccag gaaaaattgg
    16681 aacatgtgaa tgttgcccag ctggaagaat atatcaaaca agatcagttt gcaccaggta
    16741 gcatgcttcc aaaagtagaa gcagctatcg cttttgtcaa tggtcgtcca gaaggaaaag
    16801 cagttattac ttcccttgaa aatctaggcg ccttgattga atctgaaagc ggaacaatta
    16861 ttgaaaaagg ataagttgtt ttactaataa gatgtattct atttctagta tctttatatc
    16921 aaattagaaa ttattcttga aaacatgtac aatatttcaa aagatactag ttttagactt
    16981 taatatggta aaacaaatat aaatagaaag cgttttcttg aatgtttatt taagaaagta
    17041 gttggttttt tacactttgt tagacatcag gaggaaaaac aaatgagtga aaaagctaaa
    17101 aaagggttta agatgccttc atctcaaacc gtattattga taatcattgc tattatggca
    17161 gtgctaactt ggtttatccc tgcgggggcc tttatagaag gtatttacga gactcagcct
    17221 caaaatccac aagggatttg ggatgtcctc atggcaccga ttcgggctat gctaggtact
    17281 catccagagg aaggttcgct cattaaagaa acgagcgcag cgattgatgt agccttcttc
    17341 atccttatgg ttggtggttt ccttggcatt gtcaacaaaa ctggtgctct tgacgtaggg
    17401 attgcctcta tcgtgaagaa gtataagggc cgcgaaaaaa tgttaatttt ggtactgatg
    17461 cctttgtttg ccctcggtgg tacaacttat ggtatgggtg aagaaacaat ggccttctat
    17521 ccactccttg tgccagttat gatggccgtt ggttttgata gcctgactgg tgttgcaatt
    17581 attttgctcg gttctcaaat cggctgtttg gcatctactc tgaatccatt tgcgacaggt
    17641 attgcttcag cgactgcggg agttggtaca ggggacggta tcgtacttcg tctgatcttc
    17701 tgggttacct tgactgctct tagtacttgg tttgtttacc gttatgcgga taagattcaa
    17761 aaagatccga ctaagtcact ggtttatagt actcgcaaag aagatttgaa acactttaac
    17821 gtagaagaat cttcatctgt agaatctaca cttagcagca aacaaaaatc agttctcttc
    17881 ttatttgtgt tgacattcat cttgatggta ttgagcttca ttccatggac agaccttggc
    17941 gttaccattt ttgatgactt taatacttgg ttgactggtc ttccagttat tggtaatatt
    18001 gtcggttcat ctacttctgc actaggtact tggtacttcc cagaaggcgc aatgctcttt
    18061 gcctttatgg gtatcctgat tggtgttatt tatggtctta aagaagataa gattatctct
    18121 tccttcatga atggtgctgc tgacttgctc agtgttgcct tgatcgtagc gattgctcgt
    18181 ggtattcaag ttatcatgaa cgacggtatg attaccgata caatcctcaa ctggggtaaa
    18241 gaaggcttga gcggtctatc ttcacaagtc tttatcgttg taacttatat cttctatcta
    18301 cctatgtcat tcttgatccc atcttcatct ggtcttgcca gcgcaactat gggtatcatg
    18361 gctccacttg gagaatttgt aaatgtccgt cctagcttga ttatcactgc ttaccaatct
    18421 gcttcaggtg tcttgaactt gattgcacca acatctggta ttgtgatggg agctcttgca
    18481 attggacgta tcaacattgg tacttggtgg aaattcatgg gcaaactcgt agtcgctatt
    18541 attgtagtga ccatcgccct tcttctcctt ggaaccttcc ttccattcct ataaaatagt
    18601 gagtgaggtg attccatgaa aatagatata acaaatcaag ttaaagatga atttcttata
    18661 tcattaaaaa ccttgatttc ctatccttca gtactcaatg aaggagaaaa tggaacacct
    18721 tttggacaag caatccaaga tgtcctagaa aaaactttag agatttgtcg agacataggt
    18781 ttcactacct atcttgaccc taaaggttat tacggatatg cagaaatcgg tcagggagca
    18841 gagcttctgg ccattctctg tcatttggat gttgttccat caggtgatga agcagattgg
    18901 cagacaccgc catttgaagc aactatcaaa gacggctggg tattcggacg tggtgtccaa
    18961 gatgataaag gcccttcgct cgcagctctc tatgcagtaa aaagcttgct ggaccaaggt
    19021 attcagttca aaaagcgcgt acgctttatc tttggtaccg atgaggaaac cctctggcgc
    19081 tgcatggcac gctacaatac catcgaagaa caggccagta tgggctttgc acctgactca
    19141 tcttttcctc tgacctatgc tgaaaaaggg cttctacagg tcaaacttca tggccctgga
    19201 tcggatcaac tagagcttga agtaggaggc gcctttaacg ttgtaccaga caaggccaac
    19261 taccaaggtc ccctctatga acaggtttgt aacgatctca aagaagctgg ttatgattac
    19321 caatccactg aacaaaccgt aacggttctc ggagtgccaa agcatgctaa ggatgctagt
    19381 caaggtatca atgctgtcat ccgactagct accattcttg ctcctctcca agaacaccct
    19441 gctctcagct ttcttgcaac acaagcaggt caagacggca caggaagaca aatctttggt
    19501 gatatagcag atgaaccttc tggtcaccta tcctttaatg tcgcaggtct catgatcaat
    19561 catgaacgtt ctgaaatccg tattgacatt cggactcctg tcttagctga taaggaagaa
    19621 ctagtagagt tgcttacaag atgtgcacaa aactaccaac tccgctacga agagtttgac
    19681 tatctagcgc ctctatacgt cgcaaaagac agtaaactcg ttagcacact gatgcaaatc
    19741 taccaagaaa agactggcga taacagtcct gctatttcat ccggtggtgc cacttttgct
    19801 cgcaccatgc caaattgtgt agccttcggc gccttattcc caggagcgaa gcagacagaa
    19861 catcaggcaa atgaatgtgc cgttctagaa gatttgtacc gtgctatgga tatttatgcc
    19921 gaagccgtct atcgacttgc aacttaatca ggcaactgtt tctaccaaaa aaaatcccgc
    19981 aaaatgaact gcaccccaaa agttagacag aataaatcta acttttgggg tgttttatta
    20041 tgaaattgag ttatgaagat aaagttcaga tctatgaact aagaaagcaa ggacaaagct
    20101 tcaaacagct ttcaaaaaga tttg
//
LOCUS       DAVLTT010000035        20098 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLTT010000035 DAVLTT010000000
VERSION     DAVLTT010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20098
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.035"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            1..895
                     /locus_tag="VYN15_001362"
                     /pseudo
     CDS             1..895
                     /locus_tag="VYN15_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(1012..1359)
                     /locus_tag="VYN15_001363"
     CDS             complement(1012..1359)
                     /locus_tag="VYN15_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1452672.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYANDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(1470..3245)
                     /gene="spxB"
                     /locus_tag="VYN15_001364"
     CDS             complement(1470..3245)
                     /gene="spxB"
                     /locus_tag="VYN15_001364"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV1452673.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(3452..5695)
                     /locus_tag="VYN15_001365"
     CDS             complement(3452..5695)
                     /locus_tag="VYN15_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1452674.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QAAGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLSLNPELASLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5705..6076)
                     /locus_tag="VYN15_001366"
     CDS             complement(5705..6076)
                     /locus_tag="VYN15_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV1452675.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(6087..6482)
                     /locus_tag="VYN15_001367"
     CDS             complement(6087..6482)
                     /locus_tag="VYN15_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV1452676.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAEQFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      6666..6764
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6848..7639
                     /gene="thiD"
                     /locus_tag="VYN15_001368"
     CDS             6848..7639
                     /gene="thiD"
                     /locus_tag="VYN15_001368"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1452677.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLDSVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7849..8481)
                     /locus_tag="VYN15_001369"
     CDS             complement(7849..8481)
                     /locus_tag="VYN15_001369"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1452678.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIIQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLSP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8474..9277)
                     /locus_tag="VYN15_001370"
     CDS             complement(8474..9277)
                     /locus_tag="VYN15_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1452679.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     SREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLVVSKNQVAVLGNGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(9277..9801)
                     /gene="thiW"
                     /locus_tag="VYN15_001371"
     CDS             complement(9277..9801)
                     /gene="thiW"
                     /locus_tag="VYN15_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV1452680.1"
                     /translation="MRKRQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(9806..10498)
                     /gene="tenA"
                     /locus_tag="VYN15_001372"
     CDS             complement(9806..10498)
                     /gene="tenA"
                     /locus_tag="VYN15_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV1452681.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(10509..11159)
                     /locus_tag="VYN15_001373"
     CDS             complement(10509..11159)
                     /locus_tag="VYN15_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV1452682.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(11161..12546)
                     /locus_tag="VYN15_001374"
     CDS             complement(11161..12546)
                     /locus_tag="VYN15_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1452683.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     TSIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLSHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(12547..13107)
                     /locus_tag="VYN15_001375"
     CDS             complement(12547..13107)
                     /locus_tag="VYN15_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1452684.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(13369..13457)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(13666..14295)
                     /locus_tag="VYN15_001376"
     CDS             complement(13666..14295)
                     /locus_tag="VYN15_001376"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1452685.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(14297..15079)
                     /gene="thiM"
                     /locus_tag="VYN15_001377"
     CDS             complement(14297..15079)
                     /gene="thiM"
                     /locus_tag="VYN15_001377"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1452686.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKRPNGHLPGTFKAEFINALYEITDEDVKEFKRVK"
     gene            15170..15256
                     /locus_tag="VYN15_001378"
                     /pseudo
     CDS             15170..15256
                     /locus_tag="VYN15_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(15406..16074)
                     /locus_tag="VYN15_001379"
     CDS             complement(15406..16074)
                     /locus_tag="VYN15_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV1452687.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYNV"
     regulatory      complement(16289..16377)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(16631..17767)
                     /gene="lctO"
                     /locus_tag="VYN15_001380"
     CDS             complement(16631..17767)
                     /gene="lctO"
                     /locus_tag="VYN15_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV1452688.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDKRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGTQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(18392..19882)
                     /gene="lysS"
                     /locus_tag="VYN15_001381"
     CDS             complement(18392..19882)
                     /gene="lysS"
                     /locus_tag="VYN15_001381"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV1452689.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYTNLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(20010..>20098)
                     /locus_tag="VYN15_001382"
     CDS             complement(20010..>20098)
                     /locus_tag="VYN15_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV1452690.1"
                     /translation="EPMAQQVIPKAAFGYIASGAGDTFTSFQ"
BASE COUNT         6031 a         4372 c         3743 g         5952 t
ORIGIN      
        1 acgatttggc gaaatgtaaa aaaatatgag gagttcggac tcgactctct ccttcaagaa
       61 acacgtggtg gtcgtaacca tgcatatatg acagttgagg aagagaaagc ctttcttgcc
      121 cgccatttga aggctacaga ggcaggagaa tttgttacaa ttgatgcctt atttcaggct
      181 tataaaaagg agttaggtcg ttcctacaca cgtgatgcct tctatcaact gttgaagcgc
      241 catggttggc gaaatattac gccacgtcca gaacatccta agaaagcaga cgctcaaacc
      301 attgttgcgt ctaaaaataa aatctcaatc caagaaggca agaaagcgtt ttaaatatag
      361 tagacgtttt cgtaaggttt gcttgatgta ccaagctgaa gctggtttcg gtagaatcag
      421 taaactggga tcttgttggg ctccaatagg agtaggtcca catatccata gtcactatat
      481 acgagaattt cgctattgtt atggagctgt tgatgcctat acaggcgaat catttttctt
      541 aatagctggt agatgtaata ctgagtggat gaacgccttt ttagaagagc tttcacaagc
      601 ttatccagat gattatcttt tactcgttat ggacaatgct atatggcata aatcaagtac
      661 cttaaagatt ccgactaata ttggttttgc atttattcct ccatacacac cagagatgaa
      721 ccccattgaa caagtgtgga aagagattcg taaacgtgga tttaagaata aagcctttcg
      781 aattttggaa gatgtcatga atcaactcca agatgtcata caaggattgg agaaggaggt
      841 gataaagtcc atcgttaatc ggagatggac tagaatgctt tttgaaagca gatgagtatt
      901 atatgcaatt tctttatata aaaagaccgg attgctccga tctttcaata gttcatattc
      961 tcaatttcta ttttaaaaat agctaaggtt aacgtcaaat gactacgcga cctatttcat
     1021 acgataaaaa tcaagcacta gaccagcagg tccttgaact aataaggact ctgttcccca
     1081 atcggttaca gttggtccgt gtaaaacctt tataccaagc tcgttcaacc gtttgtagtt
     1141 ctggtctaca tcctcaacct cgatatgaat aatgattcct gactgaaagt tttccaaagg
     1201 aaccaaatga ttttgtgaca acataaggca gtgactacca atcgtaaact gagcaaaacc
     1261 atcattagca taatctgcct ttttatccaa gatatgctcc aagtcagcac agacttgggg
     1321 aacatttgaa acgataatat ctaattgatt taaattcatt tactctcctc cataaaaaga
     1381 ccggattgct ccgatctttt aaagttctgc tctatgaaaa tcaaagaata aagtctacaa
     1441 gtttcatatt tgattttcgg cgagaggaat tatttaattg cgcgtgattg caatccttct
     1501 tcttccaaga agagacggaa tggtacgagt tcttctgctt cgtatttttc cttgaaggct
     1561 ttgatagctt cttctgagtg aagttttgga tccaattcaa gtacttctac tggaagtgga
     1621 cggtgttgag tgatgcgagc atcgatgaca acagttttac cttctttgtt caatttaaca
     1681 gcttctgcaa caactgcatc gatgtcttcg atacggtcaa ctgtgaatcc aacagctcct
     1741 tgagcttccg caattttagc gtagtcagcg tttgtgaagt ctacaccaaa caagtgtttg
     1801 tttgtatctt cgtatttgtt cttgatgaag ccgtactcag catttgagaa gacaaggttg
     1861 ataactggaa ggtcgtattg aacgtttgtg ataacgtctg ggtagcacat gttgaatgct
     1921 ccgtcaccca tgatgttcca tacttggcga tctggattgt ctttcttagc agcgatacca
     1981 ccaggaaggg caatacccat tgtcgcaaag agtggagatg tacgccacat gttcttaggt
     2041 gtcatgtgaa ggtgacgagt agatgtttga gtagtgttac ctacgtcgat tgagtagata
     2101 gcgtcttgat cagcatgttt gttgattgca ttgtaaactt gatacaattg caattcaccc
     2161 tcagttttac cttcgagttt gttcatgtaa tcacgccagt tttggttgtt cttaacgttt
     2221 gcacgccacc atggagttga ttcaactggg tttactttgt caaggatagc tttagctgct
     2281 tgaccagcat caccaaggat tgaagcgtca agggcatgac gtttaccaag tttgtaaggg
     2341 tcgatatcga cttggatgaa tttttcagtg ttcttgaatg cttcgtaaac ttcagcaaat
     2401 gggaagtttg aaccaaggaa aagaactgtg tctgcttcaa agaccacttc gttggctggt
     2461 ttccaaccaa cacggtaagc agaacctgtc aaaccttcat agttccattc gaaagcttca
     2521 aagtttttac cagttgtgat gattggtgct ttgattttac gtgacaattc agtaatcact
     2581 tcaccagctt taacaccacc aaatccagca tagataactg ggcgttcagc attgttcaag
     2641 atttcaacag ctttgtcgat ttcaacttcg ttcaaagcag gagcgatgaa tgagcgttcg
     2701 tatgaacctg aaccgtagta tgagttttca tcgatttctt ggaaaccgaa gtttactgga
     2761 atttcaacaa cagctggacc ttttttagaa actgcagcac ggcaggcttc gtcaattact
     2821 tttggcaatt gctcagcgta agctacacgt ttgttgtaaa cagcgatacc gttgtacatt
     2881 gggttttgat taagctcttg gaaagcatcc atgttcaatt cgttaactgg acgtgatcca
     2941 aggatcgcta ggaatggagt gttatccata gctgcatcgt aaacaccgtt aatcaagtga
     3001 gtcgcacctg gaccacctga accaactgca accccgattg agccgccgaa tttagcttgc
     3061 ataaccgctg caagagcacc tgtctcttcg tggcgaactt gtaagaaacg gatatctttg
     3121 tcttcagcca aagcatccat caatgagctg agtgttcctg atgggatacc gtagattgta
     3181 tctacgcccc atgttttcaa tacgttaagc attgctgcag atgcagtaat tttcccttga
     3241 gtcataatga taactctcct tcaatttttt taaacttgga gaatacgatt acatagaatt
     3301 ggaaacgttc tccaaatttt tactattcca ctgtatcata tttatgctga cttttctaaa
     3361 aatctgctca aaactctcta ttctctattc taatacagtt ttgaaagtgt tgtcatttct
     3421 gttttataac aaagaaatct agtcattact tttagtctat tttactaaaa tttaacagaa
     3481 gggaactggt cagaacagat acagaactaa aggccatggc tagacttgcc aattctgggt
     3541 tgagagacag tccaacacct gaaaagactc ctgctgcaat cggaattccg acaacattgt
     3601 agataaaagc ccagaaaaga ttgagtagaa ttcgatgaaa ggttttctta ctcatatcaa
     3661 aggcacgaac cactcctaaa agattattgg ttgtcaacac caaatctgct gactcgatgg
     3721 cgatatctgt tccagcaccc atagcaattc ccacatctgc tacactaagg gcaggagcgt
     3781 cattgatacc gtccccaaca aaggctactt tgccagccgc ttgcagttta tggatttcat
     3841 gggctttttc ttctggcaag acgcctgcaa tgacctcttc aattccgatt tgatctgcaa
     3901 tagcacgcgc cacaccagca ttgtctcctg tcagcatgac tgttcggaga ccacgttttt
     3961 ttagctgact gatggctagc ttagcatttt ccttaggaat atcttgcaaa gcaagcaagc
     4021 ctttgatttc attgtcaaca gctaagaaca caactgtctt agcttctttt tctagttctt
     4081 ctagtttatc ttgataagta ttagaaatat ccatgccatc cagcatttta gcatttccaa
     4141 gtaaaacttg ttttccattg attcgccctg aaacaccttt cccgtgcaag gcctgaaaat
     4201 tttcaacagt ttgaaactca agtccagctt cactcgctcg cttaacgata gcctcagcca
     4261 gtgggtgttg agaagcatct tccaaggagg ctgccaatcc aaacacttct acttcgtcgc
     4321 cgatgatatc tgttaccaca ggtttccctt ccgtcaaagt cccggtctta tcaaagacaa
     4381 gagtttgaac tttctggatt tcctgtaaga cagttccatt tttgaggaga acccccatct
     4441 tggcactacg tcctgtcccc accataaggg ctgtcggtgt tgcaagtccc aaggcacaag
     4501 gacaggcgat aatcaaaacc gccactccgt agagaagaga ggacacaaag ctagctccaa
     4561 gcacgaccac actatccctg agcaagacga accaaaccca aaaggtcatg attcctaaaa
     4621 tgacaactac tgggacaaaa atccctgaaa tcttatccgt caagtcctga atcggcgcac
     4681 gacttgtctg agctttcttc acaaaatcca caatctgagc caaaacagtc tctgagccaa
     4741 ctttttctgc tctaaagaca agcgttccac tatgattgat ggttgagcca atgacagtat
     4801 ctccaactgt cttgtccaca ggcagactct cacctgtcac catggattcg tcaatactag
     4861 agacaccttc tactacgaca ccatcaacag caatcttttc accgggacgc actcgaatca
     4921 ggtcgcctac cttgacttgt tccaaaggaa cttggacata actatcatca ctcaagactt
     4981 ctgcagtttt agcttgcaag tccagtaatt tctccacagc ttgggacgta ttttttctca
     5041 ttttttcctc aaaaactgct cccaaaagaa cgaaaaagag gataaatcca gcactttcga
     5101 agtaaacagg gagaccagca aagagagcaa ctaggctata gaaataagcc actagagttc
     5161 ccagcgcaac caaggtatcc atgttggcat tgtgcttttt aaaactggcc caagcactct
     5221 ggatatatgg cttacctgca actaacataa taggcgttgt tgctagaaag gttccccaat
     5281 gcatgacttg atgactaatg ctacctgtca acatcccaat catgagaatc acaagaggca
     5341 cagtaaagat actagtaatc caaaaacgtt gcaggagaga tagagatttt cgagtcttct
     5401 caacgactat atagcttccc ttttgcatct tcatgccaca agaaaattca tgtcgcccta
     5461 attcttgagg tgtaaaacga atgactttct cctcatctac gccgattggt tccaagatac
     5521 cttcttcttc aaacagaatt tccttataac agtttgaagg agtagcacga tgaaaggtaa
     5581 tctcagctgg aattcccttt tgaagctgga tatgggctgg atgatagcct ttttcagctc
     5641 ggatacggat tttttgaatg ccattttcta agcttgcttt cacaatttct gtcatagtct
     5701 ccacctactc tacaatcatc ttgccgtgca tcatgttcat accacaagca aagccaaact
     5761 ctccaacctg ctcaggcgtg atttccacta catactcttc ccccattggc aggttcgcat
     5821 gtacaccaaa atctggaaaa acaatttgat ccagacatgg tgaaggatcc ttgcggtcaa
     5881 agacaatgcg tgctggcact gatttcttga ggacaatcaa ctcaggagta tagcctccca
     5941 tgacttccac tcgaatctct tggtatccgt ttttttgctg ggctttttgt ccagattttt
     6001 caggcttttt gaaaaaccaa aacaagataa acgcgataag ggcaatacaa ataatggtta
     6061 caatactatt taacatgacg tctcctttac atacaattac atcttacttc tgttacagca
     6121 cttgatttct tctctgaaat cacagcttcc aagtcttcca agtcagtctg agtaaattca
     6181 cattctacaa tcaagtcagc caacaaattc ctaatcctac gggaacaaac cttgtctttg
     6241 atatcttgga caagtaaatc ccgactttgg tctagagtta aaagggctga ataaacaaag
     6301 aacttgcctt cttttttccg agtcaaacac tctttctcaa ccagacgagc caaaagtgtc
     6361 tgaacagtgg acttggacca atcaaactgc tctgccaaaa ccctaatcaa atctgtactg
     6421 gtctgctccc cctgcatcca aataatcttc atgacctgcc attctgcatc tgaaatctgc
     6481 attaccatac ctccaaaatc tacatttgtc aattacactc atcagtatac tatcaaaatc
     6541 tacatttgtc aattatagaa ataatatttt cttcgaaaaa tagaatttta atcatttgaa
     6601 aaacgatttg cagtcaaata ttactatata aacaataaaa atatgctata ctaaagaaaa
     6661 aagaaaacaa ccactagggg tgcgtaaagc tgagattaac gactgttaga tccctctgac
     6721 tcaatctagg taatgctagc tgatggaagt ggaaatgata atggggacta gcagtcttct
     6781 attgcctttc taaaacagac tagcttgttc ttaagaatac aaacttcagt tggttgggag
     6841 gttttagatg acttatttac ccgttgcttt gaccattgca gggactgacc ctagtggtgg
     6901 tgctggcatt atggcagatt taaagtcatt ccaagcgaga gatgtctatg gaatggctgt
     6961 tgtaaccagt cttgtcgctc aaaataccag aggtgttcag ctaatcgaac acgtttctcc
     7021 tcaaatgttg aaagcccaat tggacagtgt cttttctgat attccacctc aggctgtaaa
     7081 aactggaatg ttggctacta ctgaaatcat ggaaatcatc caaccctatc ttaaaaaact
     7141 ggattgtccc tatgtccttg atcctgttat ggttgctaca agtggagatg ccttgattga
     7201 ctcaaatgct agagactatc tcaaaacaaa cttactacct ctagcaacta ttattacgcc
     7261 aaatcttcct gaagcagaag agattgttgg tttttcaatc catgaccccg aagacatgca
     7321 gcgtgctggt cgcctgattt taaaagaatt tggtcctcag tctgtggtta tcaaaggcgg
     7381 acatctcaaa ggtggtgcta aagatttcct ctttaccaag aatgaacaat ttgtctggga
     7441 aagcccacga attcaaacct gtcacaccca tggtactgga tgtacctttg ctgcagtgat
     7501 tactgctgaa ctagccaagg gcaagagtct ttaccaggca gttgataagg ccaaggcctt
     7561 tatcacaaaa gctattcaag atgcccctca actcggtcat ggttctggtc cagtcaacca
     7621 tacaactttt aaagattaag aaaaaaaact ctctagttcc cactttaagg gaattagaga
     7681 gtttttatac tcttcgaaaa tctcttcaaa ctacgtcagc ttccatctgc aacctcaaaa
     7741 cactgttttg agctgacttc gtcagtctta tctaaaacct caaggcagta ctttgagcaa
     7801 cctgcgacta gctttctagt ttactctttg attttcattg agtattaatt aggaaagaat
     7861 gtcatgcaac tttgttaaaa aggcttgcgt ttttgcctca atatcttctg cttgcatcaa
     7921 atcacgtaca acagctacac cagctatgcc agtgcccata agctgatcaa tattctccga
     7981 agtcaagccg ccaatagcaa ctattggaat ggcaaccgtt tggcaaattg ttttcaaggt
     8041 tgaaatcagg gtgatgggtg cattttcctt ggtggttgtc ggaaaaatgg ctcctgtccc
     8101 caagtaatct gcacctgatt tctccgcttc cagagctctt ttaaccgttt tagcggtgac
     8161 accgaggatt ttttcaggac tcaagacttg tcgggcaacc gaaactggga gttcgtcatc
     8221 tccaatatgc agaccagcag catcaaccgc aagacaaaca tccaaccgat catcgattat
     8281 caagggtacc tgataagcat ctgttatttc cttgacttgt tttgccagtt gataatattg
     8341 attggttgtg agattttttt ctcgcaattg gattatggta acccctgaac ggcaggccgt
     8401 ctcaactttt gcaagaaagc tttccacgga atcttgatag cgattggtta ccagatatag
     8461 tctaagtgct tctctattca taaacctctc ctttgatggt atctagccaa ttttcatctc
     8521 ttcttaggag cgaaagctga ttgagtactt ggtaacgaaa ttcttccaat cccattcctt
     8581 gaacaactat tttctcagca gcgatattga gataagagac tgctaagcaa gaagcttcaa
     8641 aaccagtctt tccttggctg agaaaaacag ctgttaaggc tccaaccaag tctcctgtcc
     8701 ctgttatcca gtctaattca gtacagccat ttcccagtac agcgacctga tttttcgaaa
     8761 cgacgaggtc cttgggacct gtgactaaga aagacatacc aggataggtc tgacaccaat
     8821 ctttcaagac ttgaagcaaa tcctccgttt cttgatcttt agcactcgca tcgaccccaa
     8881 cgccgtggtg ctttaatcca acaagacttc gaatttctga catgtttcct ttaaggaccg
     8941 taggtctata gtctaaaagg tctttaacta agctcttacg aatggatgaa gtcgttacgc
     9001 caaccgcatc tactaccatc gggagagaag attggtttgc atacgaagct gccatgcgga
     9061 ttgctttttc cttctcagct gacaaatgcc ccaaattgat gaagagagcc tgactttgct
     9121 tagtaaaatc aagaacttca cgggaatcat ctgccatgac aggtttgcat cccagagcca
     9181 aaatcccatt tgccagcatc tcacaagaaa tctcattggt catacagtga attagggaac
     9241 tagagcctat aggaaaggga tttgtaaatt cctgcatcag tctatccttt cactaaagaa
     9301 atatccctgc acttttttaa agaattcctg cttgattaaa aatcgaaagg caataaagga
     9361 aatcgctgta ccaatcaagg ttgctccgaa aaatcgaggc gtgtagataa accagctaag
     9421 cttagcagct gatcctgtaa agagtaccat aacaggatag gaaacaatag aaccaataat
     9481 acctgttccc acaatttctc ccaaggcaga aaagtaaaat tttcgaccgt acttataaaa
     9541 gagacctgct agaagggctc caaaagtcgc tcctgtgaga gctaaaggcg gaatcccttg
     9601 agtcgtcata cgtataaagg ctgtcactgt agccatagcc aaggcataaa caggtcccat
     9661 catgattccc gctagaatat tgactacact ggacatcggt gccattccct caatccgaaa
     9721 gataggtgta aggactacat caagggcaat catcatagat aaaatggtca atttgtgaac
     9781 ttgtagttgg cgctttctca tgtttctatt cttctccttt ttctaaagac tgtaaatcgc
     9841 tcttccatgt ctggtgttgg taagccatct cccaaaactt ggcttccata tgaacactga
     9901 tgtggaaggc atctagcatt ttttgcttat ctgtctcatc actttctcga tagagctgat
     9961 tgaccagtgc tccctcctct ctgatctgtt gctctaactc atccgtaata taagtttcaa
    10021 tccattgttg atagagagga tttggtgatg gtttaagatt aagtgatttg cctatatcat
    10081 ggtataacca aggacaagga agcaagcttg caaaagctat ggctaagttc ggttctgcaa
    10141 attgcctata aatatgagaa atgtaatgat aacaggttgg agcgattgga tgttgctcca
    10201 tttcctggtc gttgatttcc aattccttga aaaattgttg gcgaataaat aactcaccct
    10261 ccactaaacc ctgagcattt tgcttcaaga gtcttttcat ctcttggttt gaagtcttat
    10321 cagccaaaag atgatagatt tctgagaaag ccttcagata gtaggcatcc tgaatcaggt
    10381 aatagcggaa aatggcaggt tctaaattcc cctcttgtaa ttgtaaaata aagggatgat
    10441 gaaaggaagc ctgccaagct ttcttggata attccatcgc aatatctgta aattccataa
    10501 taactccttt ataaaaatag actggtttga agcaataaaa agaaaagcag gtagattaat
    10561 tttgtttttt taggaatata aaaagtccga tagctattct tcaactgtgc atgttcgtca
    10621 tatccatgag cagatagagc tctcaggtaa agatggcgcc acctaaagac tgtcatcaga
    10681 accttactgt aaatcaaggg cgaccaaaaa tgcagttctt gaccacgtaa taggcaagct
    10741 tctttgaggg acttgatttc ttgctgaatg agaggaaagg aattgaatac cacaatcaag
    10801 gcataggacc aagagcgtga tagccccttt tgagccaagt acaagagaag ctcttttagt
    10861 gaaatagagg aaacaaagac aaggccgata caaactgtca caaaggccct cgttccaagc
    10921 atgactgcct gtgaagcatc tccgtgtaac tgaactgccc agtagttggc aaaagatggt
    10981 aaaatggcaa gtatgatcat ccaagctaac attttaaatc gacggtaata gagcataaag
    11041 agaatacaaa atgcgactac cgaaagattc agagcaatcg aaggaatgaa agatgtttcc
    11101 aaggataaaa tcagcaagaa gagactgata atcggtgtct gggttgctac tttgaccata
    11161 ctatctcacc tccccttggg tattgctact ctgagatgta agtggtttgg taatggtcac
    11221 ttctttcaca tgactgagcc cctgactagt catctcaatc caataatcaa ccacagaaat
    11281 caaagggtct aaacgatgac taatgagcag aaaacttctt ccttgattcc tctcctccac
    11341 aatccacttg caaaaataat ggcaggctct atcatccaaa cctgcaaaag gttcatctag
    11401 caagatcacg gaagccttac tggtcaagat ggtcaggagc tgaagaattt tttgctgacc
    11461 accacttaat tgatagggac tcttatcgac tgcctgctcc aaatcaaaat atcgtaaagc
    11521 ttgaaaaatc cgctgatttc tttcagaatc aggtccatct aattgaagct cctctcgcag
    11581 actgactcgg ataaactgct tctcagcttc ctgaacaaca cccgtcagat cacggtacaa
    11641 actctttttc tttttcagga ctgtcccctt ccatgcaatg cgccccttat acttttgaaa
    11701 ttgaagaata gagcgaaaga gggttgattt cccgacacca ttgtcaccca ggatacagga
    11761 aatcccttga tagaatgtga aatcagcaat tgaaaagagg gggcgattac caagctcacc
    11821 agtcacacgg ttcatatgga atagttccgg gctagaagca acttcctttg aagcaacctg
    11881 tgtcatctca taggaaggga tttgaaacac ttcccttagt tttccgtctc ttagctcaac
    11941 catatggtcg atataggctt tatagtcaga taaatcatgg tcgcacaaaa taactgtctt
    12001 cccatcaaga gccaactctt ttagaatctc caatatctcg attctgctct tgcggtcaat
    12061 agaagtgaag ggctcatcca agagatagac cctaggattc atggcaaaga ggacagccag
    12121 cgctgctttt tgcttttccc cacctgatag gtgatgaatg ggacggtgta agattgcctc
    12181 gcaacgacat tgctggacaa cctctgctat tttagaatca atttcctgaa ggtgatagcc
    12241 gatattctcc aaggtgaaaa tcagctcctc aaacaagttc tccatggtaa attgatgatt
    12301 gggattttga aagagaatgc caaccttctg gacacgtgcg atgatagaaa gctgactgac
    12361 ctcgctccca tctatcagga cttgaccact atagggaaga gaactgactt gggcaatgac
    12421 ttgaaaaagg ctggattttc ctgaaccact gctcccaact aacaaggtaa aggcttgcgc
    12481 atgaaaagta aaatcaaacg gctcagagaa gattggggac tgaatcgctc gtagttccag
    12541 acccatctat gcttttcctc cagttgcaaa ctgatgatag agtttgacaa tggcacgaac
    12601 caagatggta cagaagaaat aaacagaaat aaaacgtacc acaagtaagg aaaggacaaa
    12661 cggaagggaa aaggcgtagt aacctaactt aatgtattca tagacaaagc taacaagcgt
    12721 aatcccaata ctattagcag ttagagagag ccaactttca tagcgattct tagttacgat
    12781 aaaaccaaat tcacttccca aaccttgaac caagccagac aaaagagctc ctagaccaaa
    12841 ttggctacca taaaggactt cagcaagcgc agctagcact tctccaatcg ttgcacttcc
    12901 gactctcgga acaaagatgg cagcaatggg cgcagccata caccagagac cgaagaggat
    12961 ttcattggca aaggcctgca aaccaagagg tgttaagagt agactgagaa tattatacac
    13021 atatcctgaa ccaacgaaaa ccccaccaaa aaagatagac aagaaagcaa gcaagataac
    13081 atcttttaac tgccattttt tcaacataaa aaactccttt tttaaaagaa aagtggggca
    13141 ctcaagaaga ccgacctaaa tactttgtat agcagattga atttagaaca gtacacagga
    13201 atgctaaaat atttctagaa attaatttga attttctaat tgatttgttc gcatcttatt
    13261 tcaatctact atatcatctt catccagttt cgtaaaagaa aaaactctaa ttacagatac
    13321 gaattagagt tcagcttaca agattagaca gttcttttcg acatacgaaa aaaacatttc
    13381 acatttccct tcgccagtct taactgtatc aggttcaatg ggtatcatct cagcctaaag
    13441 caccccaaat gcctttatta tttaattatg tgattattat aacacacatt ttatactagt
    13501 tcaagaaatt gaactggaaa tacagccttg cactcacaaa gacagcagat ctttcttttg
    13561 caaaaaacaa atgacctgtt tgatgaatta gccattcaag ctgaatctag acatagcttt
    13621 ttaaaaaagg aaaatcctac ttacttagaa tccaaggata gatatctatt gttcactcat
    13681 ttcccgaaca gttttttcta tattttttgc atacgatatt gccgaaatga ttgaaacgcc
    13741 gtcaacattg gtctttataa tgtctttaat atgtttcgtc tgtatcccac caattgcaac
    13801 taaaggcatt tgtggcaata gttttctcat caattcaaga ccttcataac ctatagcacc
    13861 accagcatca tcttttgact gggtatcaaa tacaggccca acacctacat aatctacata
    13921 ttcaactttt gattgttgaa attcttcttc gtttcttata gaaagaccaa ttattttatc
    13981 tggcatcaat tttctaattt catcaacacc aatatcatct tgacctacat gtacgccatc
    14041 ggcgtcaatt tccattgcta aatctatatc gtcattaacg ataaatggaa cattgtattt
    14101 tttacaaagt tctttaattt ggatagctag ctcaagtttt tctaagcctt ctaaagcacc
    14161 ctcacctttt tctcgaaatt gaaataaggt tataccacct tttaaggctt cctcaacgac
    14221 tgtatataga ttttttcctt ggcaagtagt cgttccacaa ataaaatata gttttagtaa
    14281 ttctttatga aacatcttac ttcactcttt tgaattcctt tacatcttca tctgtaatct
    14341 cgtataaggc atttataaat tcagctttaa atgttccagg aagatgtcca ttgggacgtt
    14401 tttctgctat ttctccagcg atattgtaaa ccaacattgc tgtttctaat gatttcaatt
    14461 cttgaccttt ttctagtccg ataaagcttg ctactacagc tcctaataag catcctgtcc
    14521 caatgacttt cggcatcata gcactaccat tatgaatcgt taccacttct ccattaacag
    14581 caatggcatc cacttcacct gttactacta ttggaatatt gaacttctca tttgctgcta
    14641 gagcaatttc gtcaatatta tctacgcccg cactatctac tcctttagat gccacatcta
    14701 ttcctactaa agaggcaatc tcgccagcat ttcctctaat cgctgctagt ttataattgt
    14761 tgattagatc atccgctact ttttttctat attctcctgc tccacaggct acaggatcta
    14821 aaactgctgg gacattatat ttctccgcaa ttttcagagc agcttggtat aatttccaat
    14881 tttcatctgt caatgttcct atgtttatta ataaaccacc agcatacttt aacaaatcct
    14941 ctaaatctgc tggaaactca ctcatggctg gtgaggcgcc cagtgctact aatccatttg
    15001 ctgtgaaatt ttttactaca tcattggtta tacaaatgac caatggtgct ttttctttta
    15061 ataattttaa acttgtcata ttgaaatcct tccttttcac tttatacgat ctactgattt
    15121 cgatttatat ctatctttcg ttaagaaatt tttttcattt acattgaatg atttatactc
    15181 aatgaaaatc aaagagcaaa ctaggaagct aaccgcaggt tgctcaaaac actgctttga
    15241 acctgtagat aagactgacg aagtcagctc aaaacactgt tttgaggttg tggatagaac
    15301 tgacgaagtc agtaaccata cctacggcaa ggtgaaactg acgttgtttg aagagatttt
    15361 cgaagagtct tacctcatca aatttgtaaa tatcatgagc cttctctaga cattgtaacc
    15421 aatatcaaaa aaagctaatt ctaaagcgac tgcttgattc cagcgttgct gaagttctgt
    15481 caaatcttct cgatttttac cgacacgatt gagttcgtca accagaaatt gaacccactc
    15541 tgcaaagaaa ggacctctgt ggagattgat ccattccgaa tgaatataga cttcaggtag
    15601 agccaaatct ttagaacccc agtctaaata gagaccttct gcaatgacca gcataaccaa
    15661 aagatgggca tagtctgatg aagccactgc cgaatacatt agatcctgaa aggcttttgt
    15721 tacagggtgc aaagtcactt ctagatagtc attctctgct acttttaact ctttaaaagc
    15781 cttttggaaa taaccatctt catctgcttc aagaaagcct agttgcttgg caaaacgaag
    15841 cttggattca agtttatctg cgtgagctac gcaggcaccc agcatggata agaaggcatc
    15901 aaagaagtga taatcttgaa tcagatagtc ctttaagacc ttattctcaa ttgtccccgc
    15961 aaaaagttcc ttaacaaaac gatgattgat tgcagcctgc caatccttct gactgctttt
    16021 taataattct ccaacagtca aacctggctg aaatgcatag tcttgtgttt ccatatttac
    16081 ttctcctctc tttacttgtt agtaattaat aaaacagcaa gaaatatcaa gcaaaatcgt
    16141 aattccactt gatcctttta aagcacatcg agagcatttg cagagagcta actaaacaag
    16201 cctatccagt ttatataaac aaaaaactcc aattacaatc aagaattaga gttgacttac
    16261 aagattagat cgttcatttc gccatacgaa aaaacgtttc acatttccct tcgccagtct
    16321 taactgtatc aggttcaatg ggtatcatct cagcttaaag caccccaaat gtctctatta
    16381 tttaattact gaaccagtat agcaaaaaat gaaagcccta gcaagatatt tgaccgaaaa
    16441 atatctttat atataataga ttgaaattag aatagtacac atctacttct aaaacattgt
    16501 taaaaatcga tttaactgtc ctgattgatt tgtcctgttt ttattccatt ttactatggt
    16561 tttctatagc gatttattct tccaatacac gaagaaaaac ctccacattc agtggaggca
    16621 atctctttta tcaatacaat tttaagtcac gagggtcaac tgggaaagtt gggttgtatg
    16681 ggttgtgacg gagtttgaag tgtttaacat cttcaatagt ctgagttcca gacaactgca
    16741 taactgtctt caattccgca ttcaagtgtt caaagacttg acgcacacca acactaccgc
    16801 cgagagccaa gccatagata accgggcgac caatagctac caagtctgct cctgaagcca
    16861 aggctttaaa gacatgttga ccacgacgaa caccagagtc aaagacaatt ggcacacgtt
    16921 tatcaactgc ttctgccact tcttgaagcg agtcaaaggc agctggtcca ccgtcgattt
    16981 gacgaccacc gtggttggtt acccagatac cagaagctcc tgcagcaagc gaacgttcaa
    17041 cgtcctcacg gcattgtggt cccttgacat acacaggaag tcctgagtat tcagcgataa
    17101 attctacatc acgtggagac aagcgttgtt tagctgattt gtaaacaaag tccattgatt
    17161 taccagcacc ttctggcagg tattcttcaa caatcggcat gccaactggg aagacaaaac
    17221 cattacgctt atccacttca cgattccccc ctacagtagc atctgccgtc aagacaatcg
    17281 ctttataacc ttcagccttc acacgatcca tgatgtggcg gttgataccg tcatccttac
    17341 taaagtaaaa ttggaaccaa tggggtgtcc cttgaagggc ttcagaaatc tctggaaggt
    17401 caacagtaga gtaagaactg gttgtataaa gagaaccaaa ctcatgcaca ccacgcgcag
    17461 tcgccacttc cccctgttca ttcgctaatt tatgggccgc aacaggcgcc ataatgattg
    17521 gtgaagatag tttttcacct gcaaattcaa tctctgtact tggattttca acatcgcaaa
    17581 gtgtatgagg aacgatgagt ttgtggttaa aggcgcggat attctctctt aaagtgaaag
    17641 tatcttccgc cccactagcg atatagccaa atgctgcttt aggaataact tgttgcgcca
    17701 ttggctccaa atcataggta ttgatgaagt ctacatgacc ttctgcattg cttgttttgt
    17761 atgacataaa atgccctcct tgattaagta agcgtttgct ttttactaca caactataat
    17821 aactcttttt tcaatcattt tcaagagttt tgcttaaaaa ccatcttatt ttttcataca
    17881 atatactagc cctactttcc ttaaactcta aactttagtc tatattaagt gaatcgttga
    17941 gattttttgc tgccaggcat ttgaactact tttttatttg cggattctat ctactaatac
    18001 tataaaaaaa caagtgaata agacaccaga acatcctcta ataggaccta tggacttata
    18061 tcagtcccat atatactgtt taagcaagat actatcctag ttgacgctaa cttcctatcc
    18121 cacttattaa ttttttattt atagtgaatc tgaacaaatc aattggggaa tccaagtcaa
    18181 tttctagtac tttttgaaca gtttcagcgt actatcgtaa aatgaaataa aacatgcaca
    18241 aattgcttag ggaatttaaa ccaatttcta acaatgtctt agaaatcaaa gtgtactatt
    18301 tcaacttcaa tatactacac ttcattttct ccttaaattc agtctctttt tgaatcaaaa
    18361 aatcccctgg taagagccag aggataagaa tttatttcat tgttgggaag agcaatacat
    18421 cacggatagt tgttgtatca gtgaggagca tgcagagacg gtcgataccg attcccaaac
    18481 cacctgttgg tggcataccg tattcaagag cttcaatgta gtcatagtcg attcctgtcg
    18541 cttcatcatc accaagttct ttggctttag cttgggcttc aaaacggcta agttggtcga
    18601 ttgggtcgtt caactcagta aaggcattac cgtactcctt agtcatgata aagagctcga
    18661 aacggtcagt aaagcgttgg tcttcaggat ttttcttagc gagtggagat acagctactg
    18721 gatgtccata gacaaaggtt ggttggatta aagtttcttc aacaaactct tcaaagaagg
    18781 cattgatgat gtgaccaacc tcagtgtagt gtttctcaac tggaactttc ttctcagcag
    18841 cgatagcttt agcttcttcc aaagtcatgt cttgccagaa atcgacacca gtaatttctc
    18901 tgatagcatc caccatatga acacgcttaa atggttcgtt aatcttgatt tcagtacctt
    18961 ggtagttgac tgggccatca cctttgactg atttagcagc gtgttggata atgccttcag
    19021 tcaagtccat gatgtcttgg aagtctgcat aagcttggta aacttcgata gaagtgaact
    19081 cagggttatg agtagcgtcc attccttcgt tacggaagat acggccaatt tcatagacac
    19141 gttccatacc acccacgata aggcgtttta agtgaagctc agtcgcgata cgaagcacca
    19201 tgtcaatgtt ttgggcattg tggtgggtga taaatggacg ggcagcagca ccaccggctt
    19261 cattatgaag aacaggtgtt tccacttcaa ggaatccttt ttggtcaagg taacgacgga
    19321 tttcagagat gatttttgaa cgagtgacaa agcgttcaaa gctttcacga ttagaaatca
    19381 agtcaaggta acgtttacgg taaattgttt caacgtctgt caaaccatgg aatttctcag
    19441 gaagaggacg aagagcctta gacaagtgtg tgatgtgggt tgccttgata gagagttctc
    19501 ccatatccgt acgcatcact tcaccttcga caccaaggaa gtcaccaagg tctgcttttt
    19561 tgaagatttc gtagttttct tcaccgacag catccttacg aacgtagatc tgaatctggc
    19621 cttcgcggtc ttgaaggtgg gcaaaaccaa cttttccttt accacgtttg gttaccaagc
    19681 gtcctgcgat agtagctgtt tcgtttttat cgtgtaattg ttctttatcg aggttggtat
    19741 atttatcttt taattcttgt gaatttgcag tacgttcaaa acgttttccg aaaggatcga
    19801 ttccttgttc gcggagcgca gccatttttt cacggcgaac gatctgctgg tcatttagtt
    19861 cttccatatg ttctgtagac atgggatcct cctagtttta ctcaaaattg aatacgatga
    19921 gtcatttttt gcgatactcc cattttatca taaataagca agaaattcac ggataatctt
    19981 taaaaactaa aaagaacctg acgctaaaat cactggaaag aagtgaaagt atctcccgcc
    20041 ccactagcga tatagccaaa tgctgcttta ggaataactt gttgcgccat tggctcca
//
LOCUS       DAVLTT010000036        19600 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLTT010000036 DAVLTT010000000
VERSION     DAVLTT010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19600
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.036"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            115..864
                     /locus_tag="VYN15_001383"
     CDS             115..864
                     /locus_tag="VYN15_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV1452691.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVAHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            877..2049
                     /locus_tag="VYN15_001384"
     CDS             877..2049
                     /locus_tag="VYN15_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV1452692.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            2444..3307
                     /locus_tag="VYN15_001385"
     CDS             2444..3307
                     /locus_tag="VYN15_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1452693.1"
                     /translation="MIEKMELGEFYKELRLARKLKQTDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMRIGRKVVNRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKDAIHSLNKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFSYIPIFE
                     AELESMLRPYDVFEKLLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLANPQLIALFE
                     LRLQQYKKLID"
     gene            3593..3790
                     /locus_tag="VYN15_001386"
     CDS             3593..3790
                     /locus_tag="VYN15_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV1452694.1"
                     /translation="MLNLQFAETMELTEAELETVYGGELGYNAVIPGGSWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            3858..4523
                     /locus_tag="VYN15_001387"
     CDS             3858..4523
                     /locus_tag="VYN15_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1452695.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            4595..5821
                     /locus_tag="VYN15_001388"
     CDS             4595..5821
                     /locus_tag="VYN15_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1452696.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(6217..6294)
                     /locus_tag="VYN15_001389"
                     /pseudo
     CDS             complement(6217..6294)
                     /locus_tag="VYN15_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            6326..7021
                     /locus_tag="VYN15_001390"
     CDS             6326..7021
                     /locus_tag="VYN15_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV1452697.1"
                     /translation="MKEKGFWEGAQAAMPTALGYVSIGLACGIIGAPYVTPVEMGLMS
                     LFVYAGSAQFAMLALIAVKAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWQNIGM
                     SSILTDETYGVLMGELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIF
                     GLDFALVGMFIGIFASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFAT
                     LLGCTMGVVLDGQ"
     gene            7011..7334
                     /locus_tag="VYN15_001391"
     CDS             7011..7334
                     /locus_tag="VYN15_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV1452698.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGNVGSLPQIKWLDFLAIFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            7438..8268
                     /locus_tag="VYN15_001392"
     CDS             7438..8268
                     /locus_tag="VYN15_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1452699.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            8422..9276
                     /locus_tag="VYN15_001393"
     CDS             8422..9276
                     /locus_tag="VYN15_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1452700.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            9376..10749
                     /locus_tag="VYN15_001394"
     CDS             9376..10749
                     /locus_tag="VYN15_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV1452701.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLHGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVETAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            10742..11803
                     /locus_tag="VYN15_001395"
     CDS             10742..11803
                     /locus_tag="VYN15_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV1452702.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            11805..12497
                     /locus_tag="VYN15_001396"
     CDS             11805..12497
                     /locus_tag="VYN15_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1452703.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(12527..13096)
                     /locus_tag="VYN15_001397"
     CDS             complement(12527..13096)
                     /locus_tag="VYN15_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1452704.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            13231..13845
                     /locus_tag="VYN15_001398"
     CDS             13231..13845
                     /locus_tag="VYN15_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1452705.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLVGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            13847..15493
                     /locus_tag="VYN15_001399"
     CDS             13847..15493
                     /locus_tag="VYN15_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1452706.1"
                     /translation="MKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRK
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            15505..16791
                     /locus_tag="VYN15_001400"
     CDS             15505..16791
                     /locus_tag="VYN15_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1452707.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            16843..17376
                     /locus_tag="VYN15_001401"
     CDS             16843..17376
                     /locus_tag="VYN15_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1452708.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            17454..17924
                     /gene="nrdI"
                     /locus_tag="VYN15_001402"
     CDS             17454..17924
                     /gene="nrdI"
                     /locus_tag="VYN15_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV1452709.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(18217..19479)
                     /locus_tag="VYN15_001403"
     CDS             complement(18217..19479)
                     /locus_tag="VYN15_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV1452710.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT         5837 a         3504 c         4236 g         6023 t
ORIGIN      
        1 tatatgttta tttaacgaaa tattcattat taagaataag gtgaattttt ttgatgatgt
       61 ggaatttaat cagacactta gtgagttttt agataaattg tagagggaat ggttatgagt
      121 aacaatacta agtatatctt tttatctcca catttagatg acgcaatttt ttcctgtggt
      181 gattatattt caaaattaac ttcagaagga gaaattgtac ttgttattac tatattttct
      241 ggttaccctt tgagccaaca gctacagccc tctgctaagc aatttcataa gttgtgtaac
      301 cttgggaaat atccgattga agaaaggaag aaagaagaca ggttagcttg tgaacgtcta
      361 caatgtgatt ttagacactt atcgtactat gaatgtctct ataggaaaga tagaaatggc
      421 aattttctat accgtcatat ctatagtgaa ttaaaaaatg aggacacatt aaagaatgat
      481 atcataaaag agctgttaat gcatttagac gacaaatgtg tcgtatattg tccgctttca
      541 cttggtgacc atgttgctca tgtttttgtg aatagtattg gaagggcgct tgaatttatg
      601 cgttataaag taatatatta tgaggacttc ccatatgtaa gtgatagtag tatggttagt
      661 tatatgggaa aaactaaaga attaaaaatg tatcaagagg aacttgatga aaaacattat
      721 attgatagaa tatcatcaat attgtgctat aaatctcaga ttttgataat ctggaaatca
      781 gttgaaaaac ttttaaacaa tattaaagag ttgtatttaa ggaatggggc agcttattct
      841 attagatttt ggattaagaa ataaggaagt agttttatga atatagcagt aattggtttg
      901 gggcatgttg ggctggccta cgcgttacta tttgcatcta aatataaagt tgttgcatat
      961 gatatagatt ctgtaaaaat aaataattta aaaaagggca ttcttccatc taaaaatgaa
     1021 gagcttatga agtttttttg cgagaataac ttaaatatta ctttttttga tacattttct
     1081 gaaattaaaa ataatattga ttattatatt attgcgcttc cgacagatta tgatgagaaa
     1141 attggtagtt ttaatacata tgaaatcgaa caaacggtat cgaagattct gagggtaaaa
     1201 cctaatggaa agattatttt aaagtcaaca gttccgatcg gcttttcaaa caaattaaaa
     1261 aggctgtttg atacaaaaaa tatcattttt gtccctgaat ttttgagaga aggttgttct
     1321 atatatgata atttatatcc aagtcgcata gttgttggag atgagacagt tgaaggaaga
     1381 aaaattgcag agttgttcct ttcgattagt actcatagta ctgccaatat taaaaatgtt
     1441 atgttagttt ctcctactga agcagaagca attaagcttt tttctaacac attcttagct
     1501 ctccgtgttg ctttttttaa tgaactagat tcttttgctg agaggagaag tttaaatgct
     1561 gaagttgtaa taaaaggtgt ttgtttagat ccaagaattg gaaattttta taataatcct
     1621 tcttttggat ttggaggata ttgtcttccc aaagatacta aacaattaaa aaaagaattt
     1681 atagaaataa atgccccagt gatagaagcg attgatattt caaacacaaa tagaaaacag
     1741 ttcatagtta aacaaatatt ggaacgaaag ccaaagatag taggaatata taaattgggg
     1801 atgaaatata attcagataa ttacaaagag tcagctattt taagtataat taatgaacta
     1861 ttgattgtcg gtataaaaat tttagtatat gaaccaaatt taaacgttag tatagataac
     1921 gtaatttttg aaaagaattt tgaactattt acaaaacaaa gtgatctaat tgttgcaaat
     1981 agatgggata ggggccttga agcttataaa gataaagttt acacaagggg gatctggata
     2041 agagattaac tattgatatt aaaaaggcaa taatttataa aatttgtaca aaaaaatgtt
     2101 aaattttcac attttcatag tatactgttt aatagaaagt aggttctttg taaccgctcc
     2161 attataaaat cctttcactc ttccggtata ctattaggaa aaacataact ggaggatatt
     2221 ttgagctcac ccctcatcgt tccagtggct gttccccaag ctcgtgtact gcccaaaaaa
     2281 gttagacatt ctatttagaa cgaggattga gttctgtatt gtacaaggct cggtcctttt
     2341 agagtcagct taaggctggc tttttcaatc accaaagtgt cagaatgttt tgacaaatga
     2401 acacaaataa tgatataata tgcaaaagct aggaggtggt aggatgattg aaaaaatgga
     2461 actgggggaa ttttacaagg aattacgttt ggcgagaaag cttaagcaga cagatgtggc
     2521 ttgtgagggt ctaacagctt ctcagttgtc caagtttgaa ctagggcagt ctatgctgtc
     2581 tgcggataag ttgattctag ctatccaagg tataaatgtg acctttgatg agtttgggca
     2641 caagctcaac aactatcaag aatctccaca tatgcgaatc ggtcgaaagg ttgtgaatcg
     2701 ctttgcccat caggatatag ctgctttaga gcagctattg gaggaagtcg atcaagaaca
     2761 gatggcgcag acctatcgtc gtttgaatgc catcgtgatt aaagatgcca tccattcact
     2821 aaataaaagc tacccactag cagaggagga tagcgagttt ttgaccacct atctctatgc
     2881 tatcgagtct tggacctggt ttgaactcta tctcttttgc aataccatgc ccttcttgag
     2941 caatcaagat ctgatttttt tatcaacctc cttactcgaa aaatccaaag aatttaaaga
     3001 gttagtacac aatcgattgt atatgaagca aggactctta aatatcttat cagaactcat
     3061 ggagcgaaaa cttttctcct acatcccaat ctttgaagcc gagctggaga gtatgctccg
     3121 tccatacgat gtttttgaga aattattgtg gcagttttta aagaagatga gcattttcct
     3181 tcaaactaag ggaagcaatc aaaaagagat tgaacacttt atccaatctc tgcaagtatt
     3241 agcaaatcca caattaatag ccctttttga attgcgtttg cagcaataca aaaagcttat
     3301 cgattagtta gaaatggcaa aataataata atctcagcaa cgattttcaa taatgttaaa
     3361 atttgtttct tcgtatttct ccactcctca ttagtagtaa ctttattata ccagagaagt
     3421 aatcaaattc accaaaatcg caaatctgaa atttctataa gaaaaaatat caaatatgcg
     3481 attttctaaa ataagccaat tttcgtgtta tactgtactt gtaaaacact tgaagcaaat
     3541 cctaggtcgc agaagtggtt tacaaatgaa gataattgaa ggagtgtaaa agatgttaaa
     3601 tttacaattt gcagaaacaa tggaattgac agaagctgag ttggagacag tttatggagg
     3661 ggaacttggg tataatgccg ttatcccagg tggtagttgg ggaggtttag gaacgtcttg
     3721 gtcaatcact aatttctgga agaaatattt taaccatgat tcttccactg ttaatcgtcg
     3781 ccattattga tattcagagt ccttgccttt ttcttgggta gggactgtct ttatttcata
     3841 gtataggaga aaatagaatg aaaaagataa tctcacaccg ctactttatt atagtttttc
     3901 tactagttat tgctgaccag aagttcagtg ttttagtttt acgcagcgac cttgttgctg
     3961 ggctatctga ctttgcctat tatctgtcgg atatgatgtt gaattttctt gtggttttat
     4021 ttgctcttat tgctatgatt tggtcgggga aatggcagaa aatcaatagt agaaagttta
     4081 aaggatccta tcttttctat tccttcctag ctctgcttgc ttttgttgct tggaattttg
     4141 tcaccttttt tcttttccca cctactcgaa atgaaatttc ttatcaacat gctgctccta
     4201 cttttacagg agctacggca tttttgatgt atttttttta tcctgtgatt gcaggtccca
     4261 tttttgaaga catgatttat cgtggattag tgatgactgc tctggaaaaa ggaaagaaat
     4321 gggggctaga tgtacttggt tccgctgttt tatttggggt ctcgcacatt agtaatcacg
     4381 gttgggtctt gacagacttt gtcttctata tgggtggagg tcttatattt gcagtcttat
     4441 ttagaatgac aaagtcaatt tattggccta ttggactgca tatagtctac aatggcattg
     4501 gtcagctttt gatgttactg taattttggt tgttagtagt atcgcggtct atccttgggg
     4561 aaagattccc atttgaactt aagaaggagt tgtgatgaaa gtatttcttc aaaatagaga
     4621 ttttaggcaa ttaactatca accagtggat ttcaacgctt ggggatacga ttttttatct
     4681 ggcctttctg aattatgtgg cagatgcgtc ttttgcacct ttggcgattt tactcattac
     4741 gatttcagaa acccttcccc aaattttaca aatctttctg ggagttttgg cagattttca
     4801 acatcatcgt gtcttgaaat acacagtcat tagttttgca aaatttttgc tttactctat
     4861 cgtttcttta tcactttcag ggcagtcttt ctccttgttg ctagtagcat ttatttgtct
     4921 gcttaacctc ttgtctgaca cattgagtta cttttcagga gccatgctca ctccgatttt
     4981 cattagaatt attgggcaag accatctggc agaagctatt ggatttaaac agtcaactgt
     5041 tagtttagtg aaaacaatca gtaatattct aggaggagtc ttgctaggga ttctctccat
     5101 ccagttcatt tccttgctga acgctcttac ctttttaatc gcatttttag gtatcctctt
     5161 cataaaaact gacctcttga aagtagaaaa aacgattaac tatcaagaag gactctctgt
     5221 aaaatccttt tgccagcatt tgctccaatc atcgaaattg atatggaata tgaataaggt
     5281 gctcttggtt ttgtttatta tctctactag tcaagcagtg ataaatgtta cagttcctgt
     5341 ctctactcta tttttgagga atcaaccctt tttgaattta caaacaggtc aatctcttgc
     5401 cttgctatcc acttttgaac tgtcagccct gattgtcgga agccttgtaa gtggctatct
     5461 gcaacatacc atttccataa aaacagctct ctatgcctca cttgtcatcc agttgcttct
     5521 tctagtagga tttgccacag ttcgttttga ctggattctc atctttagta ccttggatgc
     5581 ctttttcgca ggtgttctct ctcctagatt gcaagaactc gtctttaaac aaatacctga
     5641 ggagtcaatg ggagcagttc aatcctctat cggtgccatt acggttgttt tacctagctt
     5701 atttacaata gctttggtaa ccattgctac tagctttgga actctggcag ttagctttgt
     5761 tttattgcta tttcttctag ttgcctttgt tatgcttctg aatattcgtg aaagtattta
     5821 gtggagaatt tctataatat atgtttgaga ctggattgcc agtcttttta tgatggtcaa
     5881 aatcaacaga cttttttctc ttttctgaat gtgttataat agactgaatc taaaatagta
     5941 cgaaacaatt gctaaaacat ttatagaaat taattttact ttcccaatcg atttgttctc
     6001 atcttatttc aatctgctat ataatagtcc atgctgtggc tggattcttt tcagcctact
     6061 tgtactcttc gaaactctct tcaaaccacg tcagcttcac tttgccgtat atatgttact
     6121 gacttcgtca gttctatcca caacctcaaa acggtgtttt gagctgactt cgtcagttct
     6181 atccacaacc tcaaaacggt gttttgagct gacttcatca gttctatctg caacctcaaa
     6241 acagtgtttt gagcaacctg cggctagttt cctagtttgc tctttgattt tcattgagta
     6301 ttattaaggc aatatgagga gaaagatgaa agaaaaagga ttttgggagg gggcgcaggc
     6361 agccatgcca acggcccttg gttatgtcag tatcggactg gcctgtggga ttatcggtgc
     6421 gccctatgtg acacctgtag agatgggctt gatgagcctc tttgtttatg ctgggagtgc
     6481 ccagtttgcc atgctggcac tgattgcggt taaagcgcct gtggcagcta ttgctatgac
     6541 ggtctttttg attaatttgc gtctcttttt gctgagctta catgcgtcga cctatttccg
     6601 tcataccagt ctctggcaaa atatcggtat gtctagtatc ttgacagatg agacctatgg
     6661 cgttttgatg ggcgagttag cccatacaga caaggtcaat cctatgtgga tgcacggaaa
     6721 caacctcaat agctatgtgg cttggtttgt ggggacagta gtcggaacgg ctctgggtgg
     6781 cctgctacca aatccagaga tctttggttt agattttgcc ctagttggga tgtttatcgg
     6841 catttttgct tcgcaattcc agattatgca aagacggatt cccgtccgaa atctactgat
     6901 tatcctagca gttgttgcgg tgtccttctt tttactctta acagtggtgt ctcagtcgct
     6961 agctgttctg tttgcgacct tgctaggttg tacaatgggg gtggttttag atggtcagta
     7021 agtatctttt attagcagtt attttctctg gcttggtgac ctggattccc cgtatgattc
     7081 ccttcatctt agtcaagtat aagggtttgc ctgcgattgt tgaacgtttt ttgaagttct
     7141 tgcccgtttc tattatcttt gctttgattc tttcaagcgt agtgacaggt aatgttggga
     7201 gtcttcctca aatcaaatgg ctggacttct tagccatctt tccaacagct tgggtagcct
     7261 ttcgctaccg caatctagtc ggaacagttc tctttggagt ggtcttaatt gcagtcttgc
     7321 gtttggtctt ttaaattacc cataaaaaaa acttatcaca gagatagata tcatataatg
     7381 gcgtaaatgc tctttttctg ttaagattat aaggtattct attttggagg aaatgacatg
     7441 aaaaaaatcg ttaaatactc atctcttgct gccctaggac ttgttgctgc aggtgtgctt
     7501 gcggcttgct cagggggtgc taagaaagaa ggagaagcag ctagcaagaa agaaatcatc
     7561 gttgcaacca atggatcacc aaggccattt atctatgaag aaaatggcga attgactggt
     7621 tacgagattg aagtcgttcg cgctatcttt aaagattctg acaaatatga tgtcaagttt
     7681 gaaaagacag aatggtcagg tgtctttgct ggtcttgacg ctgaccgtta caatatggct
     7741 gtcaacaatc ttagctacac taaagaacgt gcggagaaat acctctatgc cgcaccaatt
     7801 gcccaaaatc ctaatgtcct tgtagtgaag aaagatgact ctagtatcaa gtctctcgat
     7861 gatatcggtg gaaaatcgac ggaagtcgtt caagccacta catcagctaa gcagttagaa
     7921 gcatacaacg ctgaacacac ggacaaccca actatcctta actatactaa ggcagatttc
     7981 caacaaatca tggtacgttt gagcgatgga caatttgact acaagatttt tgataaaatc
     8041 ggtgttgaaa cagtgatcaa gaaccaaggt ttggacaact tgaaagttat cgaacttcca
     8101 agcgaccaac aaccgtacgt ttacccactt cttgctcagg gtcaagatga gttgaaatca
     8161 tttgtagaca aacgcattaa agaactctac aaagacggaa cgcttgaaaa attgtctaaa
     8221 caattcttcg gagacactta cctaccggca gaagctgata ttaaataatt tcttgaaatc
     8281 atccattctg agtaagatgg gtggtttctc agtttttagg gatatagttt taaactatat
     8341 atctgattat ctaataacaa tttgtgaaat caaacaaatt gtgagatact agtacggtat
     8401 tatttttaag gagaaagaat catgaaaatc aaaaaatggc ttggcctagc agcccttgct
     8461 acagtcgcag gtttggctct tgcagcttgc ggaaactcag aaaagaaagc agacaatgca
     8521 acaactatca aaatcgcaac tgttaaccgt agcggttctg aagaaaaacg ttgggacaaa
     8581 atccaagaat tggttaaaaa agacggaatt accttggaat ttacagagtt cacagactac
     8641 tcacaaccaa acaaagcaac tgctgatggc gaagtagatt tgaacgcttt ccaacactat
     8701 aacttcttga acaactggaa caaagaaaac ggaaaagacc ttgtagcgat tgcagatact
     8761 tacatctctc caatccgcct ttactcaggt ttgaatggaa gtgccaacaa gtacactaaa
     8821 gtagaagaca tcccagcaaa cggagaaatc gctgtaccga atgacgctac aaatgaaagc
     8881 cgtgcgcttt acttgcttca atcagctggc ttgattaaat tggatgtttc tggaactgct
     8941 cttgcaacag ttgccaacat caaagaaaat ccaaagaact tgaaaatcac tgaattggac
     9001 gctagccaaa cagctcgttc attgtcatca gttgacgctg ccgttgtaaa caataccttc
     9061 gttacagaag caaaattgga ctacaagaaa gcacttttca aagaacaagc tgatgaaaac
     9121 tcaaaacaat ggtacaacat cattgttgcg aaaaaagatt gggaaacatc acctaaggct
     9181 gatgctatca agaaagtaat cgcagcttac cacacagatg acgtgaaaaa agttatcgaa
     9241 gaatcatcag acggtttgga tcaaccagtt tggtaataag aaacagggag gtgggagaga
     9301 gaattccacc tcttgctttt gtatagagca cggagtgtaa agaagactat tcgttcatag
     9361 aaaggtagag agaatatggt ttttcctagc gaacaagaac agattgaaaa atttgaaaag
     9421 gatcatgtag cccagcatta ttttgaggtt ttgcgtacct tgatttctaa gaaatcagtc
     9481 tttgcccagc aggttggact caaggaagtc gcaaattatc tgggtgagat tttcaagcgt
     9541 gttggagctg aagtggagat tgatgagagc tatacagcgc cctttgtcat ggcacatttc
     9601 aagagttcgc gtccagatgc caagaccttg attttctata accactatga cactgtgcca
     9661 gcggatgggg atcaggtctg gacagaggat ccttttacgc tttcggtccg caatggcttc
     9721 atgtatgggc gtggggttga tgacgacaag ggtcatatca cagctcgctt gagtgctttg
     9781 agaaaatata tgcagcacca tgatgattta cctgtcaata tcagctttat catggaggga
     9841 gcggaggaat cggcttcaac agacctagat aagtatttgg aaaagcatgc agacaaactc
     9901 catggggcgg atttgttggt ctgggaacaa gggaccaaaa atgccttgga acaactggaa
     9961 atttctggtg gcaataaggg gattgtgacc tttgatgcca aggtaaaaag cgctgatgtg
    10021 gatatccact cgagttatgg tggcgttgtg gaaacagctc cttggtatct cctccaagcc
    10081 ttacagtctc ttcgtgctgc ggatggccgt atcttggttg aaggcttgta cgaagaagta
    10141 caagagccca atgaacgaga aatggccttg ctagaaactt atggtcaacg aaacccagag
    10201 gaagttagtc ggatttatgg attggagttg cctctcttac aggaggagcg gatggccttt
    10261 ctaaaacgtt tctttttcga gccagcgctt aatatcgaag gaatccagtc tggttatcaa
    10321 ggtcagggtg ttaagactat tttgcctgca gaagccagtg ccaagctaga ggttcgtctg
    10381 gttccgggct tagaaccgca tgatgttctg gaaaaaattc ggaaacagct agacaaaaat
    10441 ggctttgata aggtagaatt atactatacc ttgggagaga tgagctatcg aagcgatatg
    10501 agcgcaccag ccattctcaa tgtgatcgag ttggccaaga aattctatcc acagggcgtt
    10561 tcagtcttgc cgacgacagc ggggacagga cctatgcata cggtctttga tgccctagag
    10621 gtaccaatgg ttgcattcgg tctaggaaat gccaatagcc gagaccacgg tggagatgaa
    10681 aatgtgcgaa tcgctgatta ttacacccat atcgaattag tagaggagct gattagaagc
    10741 tatgagtaga gatattatca agttagatca gatcgatgtg acttttcacc aaaagaagag
    10801 aaccattaca gcggttaagg atgtgaccat tcacatccaa gaaggggata tctacggaat
    10861 cgttggatat tctggagcag ggaaatcaac ccttgtacgg gtgattaacc tcttgcaaaa
    10921 accatctgca gggaaaatta ccattgacga cgatgtgatt tttgacggca aggtgacctt
    10981 gacggcagag cagttgcgtc gtaaacgtca agatatcgga atgattttcc agcattttaa
    11041 cctgatgagc caaaagacag cagaggagaa tgtagccttt gcccttaaac actctgaact
    11101 cagcaaggaa gaaaagaagg ctaaagtagc taagttgttg gacttggttg gtttggcaga
    11161 tcgtgctgaa aactaccctt cacaactatc tggagggcaa aaacagcgtg tggcaattgc
    11221 gcgtgccttg gccaatgatc caaaaatctt gatttcagac gagtcaactt ctgcccttga
    11281 ccctaagaca accaagcaga ttttggcctt gttgcaagat ttgaaccaaa aattaggctt
    11341 gactgttgtc ttgattacgc atgaaatgca gattgtcaaa gacattgcca accgtgttgc
    11401 agttatgcag gatgggcatt tgattgaaga gggtagtgtg cttgaaatct tctcaaaccc
    11461 taaacaacct ttgactcaag actttatctc aacagctaca ggtattgacg aagccatggt
    11521 caaaatcgag aagcaagaaa tcgtggaaca cttgtctgaa aacagtctct tggtgcaact
    11581 caagtacgct ggagcttcaa cagacgagcc acttttgaat gaattgtaca agcattacca
    11641 agtaatggct aatattctct atgggaatat cgaaattctc gatggtactc ctgttggaga
    11701 attggtggtg gtcttgtcag gtgaaaaagc agcgttggca ggtgcccaag aagctattcg
    11761 ccaagcaggt gtacaactaa aagtattgaa gggagtacag taagatggaa tcattgattc
    11821 aaacctattt accaaatgtc tataaaatgg gttgggctgg tcaggcaggc tggggaacgg
    11881 ctatctactt aactctttat atgacagttc tttccttcat tatcggaggc ttcttggggc
    11941 tagtggcagg tctctttctc gtcttgacag cgccaggtgg tgtcttggag aataaagtcg
    12001 tattctggat tttagacaaa attacctcaa tttttcgtgc ggttcccttt atcatcctct
    12061 tggcaatctt gtcaccactt tctcacttga ttgttaaaac aagtatcggg ccaaatgcag
    12121 cccttgtccc actttctttt gcagtctttg ccttctttgc ccgtcaggtg caggttgtct
    12181 tggctgaatt ggatggcggt gtcattgagg cggctcaagc gagcggagcg actttctggg
    12241 acatcgtggg tgtttaccta tcagaaggtc ttccagattt gatccgtgtg acgactgtga
    12301 ccttgatttc ccttgttggg gaaacagcta tggccggtgc ggttggagct ggtggtatcg
    12361 gtaacgtagc catcgcttat ggatttaacc gctacaatca cgatgtgacc atcttggcaa
    12421 ccatcattat cattttgatt atctttgcaa tccaattctt gggagatttc ttgactaaga
    12481 aattgagcca taaataaaaa agagccgcgt ggctcttttt aactgatcag attttctgtg
    12541 caaatttttt actcaaggct tgtccaatca aggcacccac tagggctccg atgacaatac
    12601 ttgcgataaa tagaaggaca gttccagggt ttggagcgac catgatgcgg tcgatatatt
    12661 cttgggattt tcctcttgcc agaagagtag ccatataggc tttgggcgca atccacataa
    12721 gcaagattgg tcctgttgta ctaaaggcga aaataatgaa agaaaggaag ttctttgttt
    12781 tgtccttgta ttttcctaaa tgagctactc catctgctag gaggccacag ataattccag
    12841 gaaggaagga accagcaccg tgtttagttc ccaagaaaaa gagggcaatg acaaggccga
    12901 tagtggtaat ggctccaaag cgcggaactt ttgcgactag gatcatatag acgctaccgc
    12961 cgacaagggc agtaaaggca ggcgcataaa acatgtttcc agtttggtca aagagattgc
    13021 ccaaaaggac accaatcccc atgcagagga agtaaagaac tgcaaaaagc agtgtagtta
    13081 agatagattt cttcatgaat tgtctcctga taattttttc acaattctca ttgtaccacg
    13141 gtttggtggg attgtaaatg gatactagaa gtttttgaaa acgcttgaaa tatgatataa
    13201 tggtttcata gttattttta ggggaatatc atgggtagat ttttagactt tgtctttaat
    13261 cgtttctttt tagggatgat tgcgacagcc ttcttttggc tattaacttt agtaggaggg
    13321 attatccttg gtctagcgcc agctagtgcc accttgatga gcttatatgc agaacatggt
    13381 tatagctttc gggaatacag tttgaaggag gcttggtctc tttacaagca aaattttgtc
    13441 tcaagcaacc tgattttcta tagcttttta ggtgtgggtc tagttttgac ctatggtttg
    13501 tatctcttgg tgcaattgcc tcatcagacc attgttcatt tgattgcgac ccttttgaat
    13561 gtcctagtag ttgccctgat ctttttggct tatacagtat ctttaaaatt acaagtttat
    13621 tttgccttgt cctatcgaaa tagtctcaaa ttatccttga ttggcatctt tatgagtcta
    13681 gcagctgtgg ccaaggttct ccttgggact gtgctacttg tagcaattgg ttactatatg
    13741 cctgccctgc tattttttgt aggaattggg atgtggcatt tctttatcag tgatatgttg
    13801 gaacctgtct atgaaatcat ccatgaaaaa ttggcgacaa aatagaatga agcacttttg
    13861 gctacatacg cttctaagaa cctatagttc agtgatgatc attatcattg cgagttttgc
    13921 aatcttactc tcttacgctg actgggattc acgtgaaaag gaagcccaga gagtagccca
    13981 gcgtgtaact gctagaacag tgagtgaaat tgaatattac catagagagt caacccagat
    14041 agctcaggct ttagttgaaa atcaagctcg tattgaggga atctataaat actttagcct
    14101 tagcatgcca gactattttt actggcaatt agagcggaaa gcttcgcctt atatatcagt
    14161 ctctctgtat gaaaatgttg atgacctcta tgttcgaaat gattttgtaa ctggagtggc
    14221 cattgctttt caagattaca aggaagtcta tgtttctact aaagacaaac gtagtggaga
    14281 aaaaatcagg gctgaggatt tcaaaccagc aggaaatagt tttgccattc cggtgtcaga
    14341 tccagtgtca gatcaagatt taggagtgat ttacatctcc ttggatcctg ctgttttata
    14401 ccatgccatt gataatacta gaggtcatac tccgatggca gtaacagtga cctcaccttt
    14461 tgatacggag atttttcata ttggtgagac agttgataag gagagtgaaa attggctagt
    14521 tggcttaact tctcatggat atcaggttca ggtggcagtt cctaaaaact ttgttttaca
    14581 aggaacagtg actagctctg ctttgattgt gggtttgagc cttctcttta ttgtcattct
    14641 ttatctgact ttgaggcaga cttttgctaa ttaccaaaag caggtagtgg atttagtaga
    14701 atccattcaa gtcattgctc aaggcgaaga ggggcgtcgg attgacattt ccgagaaaga
    14761 tcaggaatta ctcctaatcg cggagacgac caatgatatg ttggatcgat tggaaaagaa
    14821 tatccatgat atttaccagt tagagcttag tcaaaaagat gccaatatgc gagccttgca
    14881 ggcgcaaatc aatcctcatt ttatgtataa tacgctggag ttcttacgca tgtatgcagt
    14941 tatgcagagt caagatgagt tggcagatat catttatgaa ttcagtagtc tcttgcgtaa
    15001 caatatttcc gacgaaagag agaccctcct caaacaggaa ttagaatttt gccgtaaata
    15061 cagctatctc tgcatggttc gctatcccaa gtccattgcc tatggtttca agatagatcc
    15121 agagttagag aatatgaaga ttcccaagtt taccttgcaa ccgctggtag aaaactattt
    15181 cgcgcatggt gttgaccaca ggaggacaga taatgtgatt agcatcaagg ctcttaaaca
    15241 ggatgggttt gtggaaattt tggtggtcga taatggtaga ggaatgtcgg ctgaaaagtt
    15301 ggcaaatatc cgagaaaaat taagtcagag atattttgaa caccaagcca gctacagtga
    15361 tcaaaggaag tctatcggga ttgtcaatgt acacgagcgt tttgtgctct attttggaga
    15421 ccgctatgcc attacgatag agtctgcaga gcaagccggt gttcagtatc gtattacaat
    15481 tcaagatgag tagaaaggga gaaaatgtat aaagtattat tagtagatga tgagtacatg
    15541 gtgacagaag gtctgaagcg tttgattccc tttgataagt gggatatgga ggtcgtcgca
    15601 acagccagtc atgccgatga agctctagaa tatgttcagg aaaatcctgt cgatgtcatc
    15661 atttccgatg tcaatatgcc agacaaaaca gggcttgata tgattcggga gatgaaagag
    15721 atcttaccag atgctgccta tatcctgctc tcaggttatc aggagtttga ttatgtaaaa
    15781 agagcaatga accttagtgt ggtggactat ttggtcaaac ctgttgataa ggtagagctg
    15841 ggaaatctgc tggagaagat tgcaggtcag ctcggcgaga gagggaagaa aagtcagact
    15901 cttagtcaag aattagacga ggctggattt gttagttatt taggggataa ggagaattgg
    15961 tggataggtc tatccaagga aaaacaaggt tccttcacca ttccctacta tgtcttgggc
    16021 caagactggc agattttcat ttctgaccaa cccctagatg gtttagtcgt tacacctttt
    16081 gaagctcctt atcaagaaca ctttgaacgc tggaagctga atgctgagaa aaccctcttt
    16141 tacggttctg taaatttgca gcagtctgag agtctctttg cctattacga accgatttat
    16201 agggttatca ttcagggaaa tctcaatcaa atcgtagaag agttaaatct cttggagaag
    16261 gtagttcttg aaaatacgcc gcgtgttccg attactaaac agctttttat tcagtttgtc
    16321 atggatgttt tccatttatt tgaacatctc aaagctgatg acctgacaga catcgtcaaa
    16381 accattcatg ctattcaatc cttcgatgaa ttggttcctt atatcaagga aactctgacc
    16441 agctttttcg gtcaataccg tatgaatgaa aatgtggtca gtgtgctgga agtcattggt
    16501 cgtgattacc aaaaagagct ttccctcaag gatatcagta aggctctctt tatcaatcct
    16561 gtctatctag ggcagttgat taagcgtgaa accgattcga cttttgcaga gttactaaac
    16621 aaacaacgta ttaaggctgc ccaacaactt ttgctttcaa ctagtgacag catcgaagat
    16681 atttgttatg ctgttggtta cagtaacctt ggatatttct ataaagtttt ccgaaagttg
    16741 tgcggaaaat cgccaaaagc ctaccgaaaa caggtagaaa ctatactata aaatttgtat
    16801 tcctttacaa aaggtgctat aatattatca ggaggttcta tcatgaaaaa gaaaccaatt
    16861 tatctatggg tcttgctaat cttgtctgcc cttatttcag ttccgtctct gtttggaatt
    16921 gtgagtccct tgcctagtaa agaagccctt cgtgctgctc agaaacaagt tgcaggggtc
    16981 aatgctcagc aattagaaga ccagcttaat tatacctata gagtagcaga agcatctcat
    17041 tctattttta atgttgcttt gattgtgcta tctactattt tagtggtcgt agcgattgtc
    17101 ttccttgttc gtaaaaattt gcaatatgca aactatactt acgttggcta tgttttgtta
    17161 gctattattg gttcgattta tggctatgtt ggtttacaag acgctgtgca gttggttcaa
    17221 gatgagagca tgcgtttgac agtgagtatt ggctcaaaag ctgttagcat tttctatatc
    17281 gtcatcaatg ttctcttcct agcccttgtc ttctataaga tgtggcgaca acagaaagcc
    17341 ttggcagaag aagaggaaac agaagagctt acctaagtat tgacaaaaaa gaactatcaa
    17401 gatacaatct tggtagttgt tttttgatta tagataaaat catggaggta catatgaaga
    17461 caatttcttt agtttatatt agtttgagtg gcaacactga aagttttgtg acgcgcttga
    17521 aagactatct cttgtcccag tacaaaggga ttgaggttca aaagattcat atcaaggatt
    17581 tggtcaagga aggcaaaaat ttctatgaaa tggaccatcc ctatgtcgct tttttgccga
    17641 cctatctcga aggtgggaat ggcgtggata acggagatgt tgagattttg acgacaccgg
    17701 tgggagattt tattgcctat ggtaacaatg ctagtaagtg ttttggtgtg gttgggtcag
    17761 gaaatcgtaa ctttaataac caatactgcc taacagccaa gcaatacagt caacgctttg
    17821 gcttccctgt attggctgac tttgaaatgc gaggcatgct ggaagatatc aaacatgtcg
    17881 cagctattat cgcagatttg tatgagttgg aaaaggagaa ttaatactca atgaaaatca
    17941 aagagcaaac taggaagcta gtcgcaggtt gctcaaagca cagctttgag gttgcagata
    18001 gagctgacgt ggtttgaaga gattctcgaa tagtataaag ttcttataag aggtggttga
    18061 agttgttcaa ctgttttttg agtataaaca gtctttaaga acgtaaaaaa gcataagttc
    18121 aggtcttcaa aaccttgttc ttatgctttt tatcatagaa atatttgctg aattttctct
    18181 tgaaatgaaa ccttatcttc atctcgcgct tgtcccttac cctgcttttc cgattgcgag
    18241 tgcgtagata aagaagatgg cgaagccaaa gaggaaaatc aatcccgcaa tggcaaggtg
    18301 tttgagccaa gaaggaagat ttttgttttc acgcgttacc aaggcgtaat tcaaaagagc
    18361 aaagaaaggt gttgtcagga aagatccaat catggcaaag cggagcatgg ttgaaacctg
    18421 accagcgaag aacttgataa tgacgatacc gatgatagca gtgatggtca tccagatgtt
    18481 caaagattta cgattgtcct ctttttgact gattagcagt cggagagatt cctgattaac
    18541 gcgagaatag ccatcgataa cagttataac tgttccaaag atacagagga aggcaataaa
    18601 ggtaatcaag taacgggacc attcgccaag aacagaggca tacatgccca cgaattgaga
    18661 gatgtatttg gctgaagcag cttcaaccgc ctgccctgta ggatactgaa tcagtgctcc
    18721 cagtgccaca aagaagacgg ctaggatagc tgttccaata taaccagtgt taaagtcaaa
    18781 cagagcgtct tctgtgttaa agttgacggt ctttctcttt tcagctgacc aaagtgaatt
    18841 gatggctgaa atttcaatag gagccggcat ccatcctagg agggagacga tgaagggcag
    18901 agctgccatt tgccaaggtg tcttctcgac aaaatcagaa ctgtattctg gatgcttgac
    18961 cgccgcaatg ataactgcaa gaacagtcgc aatggttaag gcagacataa tccatttgac
    19021 catgccgtct aaaagtttgt agcctccaaa gagtagcata gcccaaatga ttgcaacgag
    19081 aatgagggac cactgagtaa tgctaagtcc aatcattggg aaggcactgg cgatgatagc
    19141 tgagcacaga atggcaacac cagccgtgtt gaccatagcc gaaaagacat tgagaataaa
    19201 gaaaatccag agatagagtt ttcctttttc ggcataacct tcaaccaaag tctttccagt
    19261 atcagctgtg tattcagcac caaaacggaa aaatggatat ttaaagacat tggctaagat
    19321 gaccaagaga agtagagacc aaccgtaaga accgccagct tgagttgagg atacaatgtg
    19381 ggaacctcca acagcggcag ttgccattag gattccaggt cccattgctt ttagcttgct
    19441 tgcccaggtt gattgattta aggaaatagc ttgcgacatg ataaatactc ctttttgaat
    19501 tttcagaata atctgtatat gcaatctata ttctacaaaa aattttggaa aaatgcaaga
    19561 atattttgaa aaaagataga aaatttacaa agaaaatctg
//
LOCUS       DAVLTT010000037        19075 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLTT010000037 DAVLTT010000000
VERSION     DAVLTT010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19075
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.037"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            168..1649
                     /locus_tag="VYN15_001404"
     CDS             168..1649
                     /locus_tag="VYN15_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1452711.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2010..3011
                     /locus_tag="VYN15_001405"
     CDS             2010..3011
                     /locus_tag="VYN15_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1452712.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3160..4077
                     /locus_tag="VYN15_001406"
     CDS             3160..4077
                     /locus_tag="VYN15_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1452713.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKVDFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4088..4978
                     /locus_tag="VYN15_001407"
     CDS             4088..4978
                     /locus_tag="VYN15_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1452714.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5007..6623
                     /locus_tag="VYN15_001408"
     CDS             5007..6623
                     /locus_tag="VYN15_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1452715.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6633..7952
                     /locus_tag="VYN15_001409"
     CDS             6633..7952
                     /locus_tag="VYN15_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1452716.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVATKHKDNVGCIVLLGSDNLVEWQFESIFLKGREHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDH
                     GQDFYAPQTLLDNQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8159..8231)
                     /locus_tag="VYN15_001410"
     tRNA            complement(8159..8231)
                     /locus_tag="VYN15_001410"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8196..8198),aa:Lys,seq:ctt)
     gene            complement(8496..9767)
                     /locus_tag="VYN15_001411"
     CDS             complement(8496..9767)
                     /locus_tag="VYN15_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV1452717.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10037..10276
                     /locus_tag="VYN15_001412"
     CDS             10037..10276
                     /locus_tag="VYN15_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452718.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            10441..10620
                     /locus_tag="VYN15_001413"
     CDS             10441..10620
                     /locus_tag="VYN15_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452719.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10757..10936
                     /locus_tag="VYN15_001414"
     CDS             10757..10936
                     /locus_tag="VYN15_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV1452720.1"
                     /translation="MLMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            10973..11425
                     /locus_tag="VYN15_001415"
     CDS             10973..11425
                     /locus_tag="VYN15_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV1452721.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11716..12186
                     /locus_tag="VYN15_001416"
     CDS             11716..12186
                     /locus_tag="VYN15_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV1452722.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPKY"
     gene            12205..13272
                     /locus_tag="VYN15_001417"
     CDS             12205..13272
                     /locus_tag="VYN15_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV1452723.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     RYIGLKEDESDQRIILMLSGGLMVHLGLILLAILFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPADITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVVQTHKAMKIARQKMNSSRMLR
                     DEKRYYENWLAELEKELAEGV"
     gene            13274..13702
                     /locus_tag="VYN15_001418"
     CDS             13274..13702
                     /locus_tag="VYN15_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1452724.1"
                     /translation="MEIEISGFTGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECAAREVYEELGIHLTEDCLLWSKVYPSILFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            13837..14790
                     /locus_tag="VYN15_001419"
     CDS             13837..14790
                     /locus_tag="VYN15_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV1452725.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDSGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SLFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     CMENIHVAAGDLLKGVEIEADVIVANILADILVHLTDDAYRLVKDEGYLIMSGIIKDK
                     WDMVRESAELSGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            14792..15535
                     /locus_tag="VYN15_001420"
     CDS             14792..15535
                     /locus_tag="VYN15_001420"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV1452726.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELIQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFSADWSVAKWDGKKLDKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            15546..17342
                     /gene="pepF"
                     /locus_tag="VYN15_001421"
     CDS             15546..17342
                     /gene="pepF"
                     /locus_tag="VYN15_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1452727.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            17588..18142
                     /locus_tag="VYN15_001422"
     CDS             17588..18142
                     /locus_tag="VYN15_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV1452728.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPDFPINRIHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            18253..18921
                     /locus_tag="VYN15_001423"
     CDS             18253..18921
                     /locus_tag="VYN15_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV1452729.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGPIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         5869 a         3294 c         4140 g         5772 t
ORIGIN      
        1 ccctcaatag acggtaaaat aagaaaattg tttatatatt gtctccgtag tgttattata
       61 cgaaataaaa gattttagga aaagtcgtta tatcatgcta tacctattct ttgtggtata
      121 attgcaagag gtttaatccg ataatttata aagagagaaa gatattcatg agagatttat
      181 tatctaaaaa aagtcatagg caattagaat tattagaatt attatttgaa cataaacgtt
      241 ggtttcatcg ttctgaacta gcagagttat taaattgtac agaacgtgca gtcaaagatg
      301 atctatccca tgttaaatct gcttttcctg acttgatttt tcattcttct actaatggta
      361 tacgcattat taataccgat gatagtgata ttgaaatggt ttaccatcat ttctttaaac
      421 attcaactca tttttcgatt ttagaattca tcttctttaa tgaaggttgt caagctgaga
      481 gtatttgtaa agaattttat atcagttcat cttcgctcta tcgtattatt agccaaatca
      541 ataaagtgat taaaaggcaa tttcaatttg aagtcagtct gacccctgtt caaatcattg
      601 gaaatgagag agacattcgt tacttttttg cacaatattt ttcagaaaaa tattatttcc
      661 tagaatggcc atttgaaaat ttttcatcag agccactatc tcaattgtta gaattggttt
      721 ataaggaaac aagctttcca atgaatttgt caacgcatag aatgctaaag ttgctcctag
      781 ttacgaatct atatagaata aagtttggtc attttatgga agtagataaa gattctttta
      841 acgaccaaag tttggatttt ttaatgcagg cagaaggaat agaaggtgtt gctcagagtt
      901 ttgaatcaga atacaatatc tctttagatg aagaagttgt ttgccaatta tttgtgtctt
      961 actttcaaaa aatgtttttc atagatgaaa gtctctttat gaaatgcgta aaaaaggata
     1021 gttatgttga aaaatcttac catctattga gtgattttat tgatcagatt tcagtcaagt
     1081 atcagattga aatggagaat aaggataatc tgatttggca tctgcataat accgcacatc
     1141 tgtatcgtca agagttgttt actgagttta ttttatttga tcaaaaaggg aatacaatca
     1201 ggaactttca aaatattttt ccaaaatttg tttcagatat aaaaaaagag ctttctcact
     1261 atttagagac tcttgaggtt tgttctagtt caatgatggt aaatcatcta tcttatacct
     1321 tcatcactca taccaaacat ttggtgatta atttgctaca aaatcagcct aaactaaagg
     1381 ttttggttat gagtaatttt gatcagtatc atgcaaaatt cgttgcagag acactttctt
     1441 attactgtag caataatttt gaactggaag tttggaccga attagaatta tcaaaggaat
     1501 ctttagaaga ttcaccttat gatatcatta tttccaattt tattattcct cctattgaaa
     1561 ataagagact catctattca aataatataa acacggtctc actcatatat ttgttaaatg
     1621 ccatgatgtt tattcgatta gatgagtaac caaaaataac aaaaaaacgc tatttcgcgt
     1681 ttgaactgta cctcaaaagt tagacagaaa aaatctaatt tttggggtgt ttttgttaag
     1741 aaaagacctt caatcattta agcaaaatgt acatctagat ttatagccct ctaaaactct
     1801 tgtttttttg tagaagatac gaaaaaagct atgaaaccaa ggcttttcct gttttatgta
     1861 gatgtttaca catgaaaatt gaagtatttt caaaagctaa ttggagtgat tttattcatg
     1921 atgggataaa tgatctggcc aaaaatgact gagaaatagt tgcttaaaaa gcatttgcat
     1981 gatactatat attgaaagga ggtgataata tggtagaaca aagaaaatca attaccatga
     2041 aagatgttgc tttagaagca ggagttagtg ttggaactgt ttcacgtgta attaataaag
     2101 aaaaaggcat taaagaagta actttgaaaa aagtggaaca agcgattaaa actttgaatt
     2161 acattccaga ttactacgct agaggaatga aaaaaaatcg aacagaaacg attgcaatca
     2221 ttgtaccaag tatctggcat cccttctttt cagaatttgc tatgcatgtg gaaaatgaag
     2281 tctataagag aaataacaaa ttactcttat gttctatcaa tggtacaaat agagagcaag
     2341 actatctgga gatgttgcgt cataataaag ttgatggagt ggttgccatt acctatagtc
     2401 caattgaaca ttacttgacg tcaggaattc cctttgttag tattgaccgc acatactcag
     2461 atattgccat tccttgtgtt tcatcagata atgatgcagg tggaagagaa gcagctaaac
     2521 aattaattag taaaggatgt cagcatttag cctttgtggg cggacataat acaaccatta
     2581 atgaaaccaa acgtcgtaga atttcatttg aaaagtatgt ccaagagcat aaaatacctc
     2641 ttagtatttt tgatttggat gagacagtta ctgactatta tggaaagcta gagagtttct
     2701 tggaagaaaa ttcttctata gatggaattt ttacaatcaa cgattttaca gctttggatg
     2761 tgattgaaat actaaaaaaa aatggcaaac gtattcctca tgatgtccaa attattggat
     2821 acgatggaat taaaatggct ggagatagag attatctact ttcaactatt gaacaaccat
     2881 tggaagaaat ggcaaaagaa gcggttcgta ttttgtttga tataattgat ggaaagactg
     2941 ttaatttgca gacaatccta ccagtaaaat ttgttgaagg aaaaacaaca aaaaatgaaa
     3001 ataagtcttg acagaaagcg ctatcaatga tagaatgaat tcagataaaa agatttattt
     3061 ttaaaacaaa aatgaaacgt ttcaaaaaag aaataaagag acagcgtcaa gcgctatctt
     3121 ttctagaaca aaaatgaaac gtttcaaaag gaggttgcta tgaatagcaa agcgaagcaa
     3181 gtttctcttt gggaaagaat caagaaacaa aaactcttgt tattgatgac tgtccctggt
     3241 ttagttttaa cctttatctt taaatacatc cctatgtatg gggttttaat cgcatttaaa
     3301 gattacaatc ccttaaaagg aattttaggg agtgattgga ttggtttttc tgagtttaca
     3361 aaattcatat cctctcccaa ctttggtatc ttgttagcca acacattaaa attaagtatc
     3421 tatggtttat tgcttggctt tttaccacca atcattcttg ctattatgct caatcaactc
     3481 ttgagtgaaa aagtcaaaaa acgaattcag ctcattttat acgcaccaaa ctttatctca
     3541 gtcgttgtta ttgtcggtat gattttcctc ttcttttcag tgggaggacc aatcaacaat
     3601 tttctttcta tgtttggaat gaaggttgac ttcttgacaa atccagactt ctttagacct
     3661 ttatacatct ttagtggtat ctggcaagga atgggctggg cttcaacgct ctacacggca
     3721 acattggtaa atgtagatcc agccttagta gaagcagccc gactggatgg agccaatatc
     3781 ttccaacgaa tctggcacat tgatattcca gctcttaagc ctattatggt tatccaattt
     3841 gttttagctg caggtggaat tatgaatgtc ggatatgaaa aagcattctt gatgcagaca
     3901 tcgttaaatt tgccaacttc tgaaattatc tcgacatatg tctataaagt tggtcttgta
     3961 tcaggagact attcttactc aacagcggtt ggtttgttta atgcagtgat taacgtagta
     4021 ttgcttgttg cagttaacca aatcgttaaa cgcatgaata atggtgaagg aatttaagga
     4081 ggaaagtatg aaaaattcga ttatggatac aaaatttgat agacgtatct tactcttaaa
     4141 taaaatcatt attgtcttta tcgttttgat gactttgctt cctttacttt atatcgtcgt
     4201 agcatccttt atggatccta aggttctggt tagtagaggg attagcttta atccagccga
     4261 ttggactgta gaaggttacc agcgtgtatt cagtgaccaa tctattctaa gaggttttat
     4321 caattctcta ctatactctt ttggatttgc agctttaaca gtcttgctat ctgtgtttac
     4381 agcttatcct ctttctaaga aagacttggt tggacgtcgt tggattaact acttcttgat
     4441 tgtaactatg ttctttggtg gtggtttagt cccaacttac ttgctcgtaa aagaattggg
     4501 aatgctcaat actccatggg ctatcattgt tccaggtgct gtcaatgttt ggaatattat
     4561 tcttgctagg gcctatttcc aaggattgcc tgaagaatta gttgaagctg ctgtcattga
     4621 tggtgcaaat gatttacaga ttttctttaa aatcatgctt cctcttgcaa aaccaattat
     4681 gtttgttctc ttcctctatg cttttgtagg acagtggaac tcatactttg atgcaatgat
     4741 ttatatcaag gatccaaact tggaaccatt gcaacttgta cttcgtaaaa ttctcattca
     4801 gagccaacca ggtcaagaca tgattggagc acaagcggct atgaatgaaa tgaaacgttt
     4861 agctgaattg attaaatacg caactattgt catttccagc ttgccattga ttgttatgta
     4921 tccattcttc caaaaatact ttgataaagg aattatggct ggttcactta aaggataaaa
     4981 aaagaaaaaa taaaaggagt tttctcatga aattcaaaac attctcaaaa tcagcagttt
     5041 tgttgacagc tagtttagca gtacttgcag cctgtggctc aaaaaataca gcttcaagtc
     5101 cagattataa gttggaaggt gtaacattcc cgcttcaaga aaagaaaaca ttgaagttta
     5161 tgacagccag ttcaccgtta tctcctaaag acccaaatga aaagttaatt ttgcaacgtt
     5221 tggagaagga aactggcgtt catattgact ggaccaacta ccaatccgac tttgcagaaa
     5281 aacgtaactt ggatatttct agtggtgatt taccagatgc tatccacaac gacggagctt
     5341 cagatgtgga cttgatgaac tgggctaaaa aaggtgttat tattccagtt gaagatttga
     5401 ttgataaata catgccaaat cttaagaaaa ttttggatga gaaaccagag tacaaggcct
     5461 tgatgacagc acctgatggg cacatttact cattcccatg gattgaagag cttggagatg
     5521 gtaaagagtc tattcacagc gtcaacgata tggcttggat taacaaagat tggcttaaga
     5581 aacttggtct tgaaatgcca aaaactactg atgatttgat taaagtccta gaagctttca
     5641 aaaacgggga tccaaatgga aatggagagg ctgatgaaat tccattttca tttattagtg
     5701 gtaacggaaa cgaagatttt aaattcctat ttgctgcatt tggtataggg gataacgatg
     5761 atcatttagt agtaggaaat gatggcaaag ttgacttcac agcagataac gataactata
     5821 aagaaggtgt caaatttatc cgtcaattgc aagaaaaagg cctgattgat aaagaagctt
     5881 tcgaacatga ttggaatagt tacattgcta aaggtcatga tcagaaattt ggtgtttact
     5941 ttacatggga taagaataat gttactggaa gtaacgaaag ttatgatgtt ttaccagtac
     6001 ttgctggacc aagtggtcaa aaacacgtag ctcgtacaaa cggtatggga tttgcacgtg
     6061 acaagatggt tattaccagt gtaaacaaaa acctagaatt gacagctaaa tggattgatg
     6121 cacaatacgc tccactccaa tctgtgcaaa ataactgggg aacttacgga gatgacaaac
     6181 aacaaaacat ctttgaattg gatcaagcgt caaatagtct aaaacactta ccactaaacg
     6241 gaactgcacc agcagaactt cgtcaaaaga ctgaagtagg aggaccacta gctatcctag
     6301 attcatacta tggtaaagta acaaccatgc ctgatgatgc caaatggcgt ttggatctta
     6361 tcaaagaata ttatgttcct tacatgagca atgacaataa ctatccaaga gtctttatga
     6421 cacaggaaga tttggacaaa attgcccata tcgaagcaga tatgaatgac tatatctacc
     6481 gtaaacgtgc tgaatggatt gtaaatggca atattgatac tgagtgggat gattacaaga
     6541 aagaacttga aaaatacgga ctttctgatt acctcgctat taaacaaaaa tactacgacc
     6601 aataccaagc aaacaaaaac tagaggttga ttatgggaga taagaaatac acagtagaaa
     6661 aagccaatcg ttttatagca gaaaataaac atctcgttaa tactcaatat aagcctgaag
     6721 aacatttttc agctgagatt ggttggatca atgatccaaa tggatttgtc tattttcgtg
     6781 gagaatacca tctcttttat caattctatc catatgatag tgtttggggg cctatgcact
     6841 ggggacatgc taaaagtaag gacttggtga cttgggagca cttgccagtg gcacttgctc
     6901 ctgaccaaga ttatgaccga aatggttgtt tctcaggctc tgccattgtc aaggatgatc
     6961 gcctctggct catgtacact ggacatatcg aagaagaaac cggtgtccgc caagtgcaaa
     7021 atatggcatt ttcagatgac gggattcact ttgaaaagat ttcccaaaat ccagttgcaa
     7081 ctggatcaga cttgccagat gagttgattg ctgctgattt ccgtgatcca aaactctttg
     7141 aaaaagatgg acgctattac tccgtagtag ctaccaaaca caaggataat gtgggctgta
     7201 tcgttctact agggtccgat aacctagtag aatggcagtt cgaatccatc tttttaaaag
     7261 ggagagaaca ccaaggcttt atgtgggaat gcccagatta cttcgagtta gatgggaaag
     7321 attgccttat tatgtcaccc atgcgttatc agcgtgaggg agactcatat cataacatca
     7381 actcatcgct tttgttcacg ggtaaggtag attggggaga aaaacgtttt atcccagaat
     7441 cagttcaaga aatcgatcat ggccaagact tctatgcgcc tcaaacattg ttggacaatc
     7501 aaaatcgtcg tatcctgatt gcttggatgc agacatgggg gcgtaccctt ccaacccatg
     7561 accaagaaca caaatgggca tgtgccatga ctttacctag aattctaaga ttggaagatg
     7621 gcaaactaag acaattccct gttaaaaaag gccaatatca aatccaaata gataaagatt
     7681 gtcattacca cttaggaaat gatatagatt atcttgaatt tggttatgac agtaatgcgc
     7741 agcaagttta cattgatcgt agccatctta ttcaaaaaat tctaggtgaa gaagaacagg
     7801 acactagtcg acggtatgta gatattgaag ctaaagaatt ggaagttgtt ctagataaaa
     7861 attccatcga gatttttgtc aatcaaggtg aagcaagctt gactgcaact tattacttaa
     7921 cggtgccagc tgagctatca cgaattgatt aaaaattaag ttatttctcc taaagaaaaa
     7981 gttctctttc taaaatagtg gaaagaggac tttttgtgtt ttgggtatat aagcttagtt
     8041 tatggtattt gtaaaattgg tgttggatta tgatttaagc tagttttcta aagaatttga
     8101 aaaaatttta tttaagcaaa aaaaccttgg ttccaaggcc tttcctgttg tatttatatg
     8161 ccccctacag ggatcgaacc tgtgacccac ggattaagag tccgctgctc tgccagctga
     8221 gctaaggagg caaagaaaaa agctgtattg gtgccgaaac ttcacggttt gtattgaacc
     8281 cgcgcaatta agcaggtggg caactcgctc taactgaagc tgtttccgtg tgagacggcc
     8341 tacatgctgt tagaagactt ttgtttccct aataatacaa aaaatagtcg gtcaacactt
     8401 aagtgtgaag tcgtacacca cagcgtttct atacttatat gataccactt tttcaaaaaa
     8461 aatcaagagg aaagtgcaat tttttgaaaa ggatttcaga tttttcgcaa acggtcgata
     8521 gcttcctttc tttgagccaa agcccgttca tatttaccag tatcttctgc ttggaaatag
     8581 tgatgattac gaattttttc tggcagatag tcttgcttga cccaatttcc aggatagttg
     8641 tgtggataga gatagtcttg ggcattcccc agttccttgc ttccactgta gtgcccatca
     8701 cgcaggtgtc gcggaatagg caagtgccct gatgttttga ggtcagcaag tgccttatcc
     8761 atagctacat aggctgagtt ggattttgga gaaagggcca aatcaatcac gacattggca
     8821 atgagaatgc gggcttcggg gaaaccaatc ctttgtgcag catccagagc agtcacggta
     8881 tgaatctggg cctcaggatt ggctaagccg atatcttcat aggcgataac agtcaagcga
     8941 cgagcgagac taggcagatc cccagcctca atcaagcggg cagtatagtg gagactggca
     9001 tccacatctg agccacgaat agacttttgc agggcagata gaacatcata gtgaccgtct
     9061 ccatccttgt ccatagtgat gtagcttctc tgaagactat tttccatgat gtctaaggtg
     9121 atgtggcgaa tgccctcgtc attctcaggg gtagagagaa cagccaagtc cagtgagtta
     9181 aaggcagagc gaaggtctcc gtttgtagag gttgcgatga aatccagcgc atcctcatct
     9241 agttctattg gaaaatcaaa accacgttca gggttactta gagctatctg cagggcctct
     9301 ttgacgtctt ggttagacag aggttccaac tcgaaaattt gaacacggct acgaatggca
     9361 ggagtgacag agaagaaagg attttcagtc gttgctccaa tcatgatgac cagtccactt
     9421 tccaagagag gcaagaggaa gtcttgcttg gtcttatcta gtcgatgaat ttcgtctagc
     9481 aataggacga gaccaccaga aaatttagct tcttccgaga tttcttgcag tcgcttttta
     9541 ctatcaactg tcgcattgaa agttcgaaag gcatacttgg tcgttccagc gatggcagag
     9601 gcaatactgg ttttgccgat tccaggaggg ccatatagaa tcatggagga caggcggttg
     9661 gcttccacca tgcggcggat gatttttcca ggtccgacca gatgctcctg accgatgacc
     9721 tggtcgatgg ttttagggcg catgcgaagc gcgagattgt ctggcatagc agtcctttct
     9781 aacgtggatt tgagtagaat gactcatcta ctatatctta ctatgtccat tctagcctat
     9841 tagttgtgat atttcaatgg ttttgtaata atcagggagt gagatagaat cttttttact
     9901 atttaattta atgaggagag gtatcagcat gagagatttg attttcctta aagctcaaaa
     9961 taggatagtt gagcctaaag aagtggaagt gctgacttga gaaataatat tgctgaatgt
    10021 cattgtatga actataatga aaagagaggt gataagcaat ggaaatgatg gaccaagtca
    10081 ggaaattttg atttttacaa aacaaattcg tcattggatt cttagtgatc aagttatttc
    10141 agggaaaaga aaacttttct tccgggaaga tactccaaaa gagattttag atttgtacga
    10201 aaacattaaa tctaaacttg attttgctta ccaagaagtt cattctaata atgggttgaa
    10261 aaaatatgaa aaatagaata attgatgttt ttgaagtagt aaatcgcctc cttgtaataa
    10321 ctgttgaaaa tcctgatttc gaagacttga gagttaatca tactcaatga aaatcaaaga
    10381 gcaaactagg aaactagccg caggctgtac ttgagtacgg taaggcgacg ttgacgtggt
    10441 ttgaatttga ttttcgaaga gtatcagttt gtaaaaattg gagataaaaa atatagagta
    10501 cgcagtgttc ctatgattca ttcaactccg cctcaatctg tcttagatcg agatactttt
    10561 acaattgact atacagatga tgaattgctc gataaagaag cagtttttac tactcattag
    10621 aaaaataggt ctgaataaat tggcttccct tagaaccaca tctaggggct tttatgtata
    10681 atagaataat aagtatcact cctttacaat acgtgtaaca cgtgttataa tggtgttgtc
    10741 aggaggtaaa agcgctatgc ttatgacaca aaaagagatg gttaaactcc ttacggccca
    10801 tggttggata aagactagag gcggtaaagg ctcccatatt aaaatggaga agcaagggga
    10861 aagacttatc acaatccctc atggtgagct gaataagtac actgaaagag ggataagaaa
    10921 gcaagctggg ttgtaaaatt cagcccctgt tttttgatat ggaggtagtg aaatgttagt
    10981 tacgtatcca gctttatttt attatgacga cacagacgga acagaagcga cttattttgt
    11041 ccatttccca gattttgaat actcagctac acaaggagag gggatttctg aggctttggc
    11101 tatggggtcg gagtggctag ggataactgt tgcagatttg atagagagtg atggagagtt
    11161 acctcagcca tcagatatca atagcttgtc tttaattgat aatgatcctt ttaaagatga
    11221 tgaagatttc gtgtcaacct atgaccttga taaatctttt atttctatgg tatctgttga
    11281 tgtatcagaa tacctaggaa gtcaggaacc cattaaaaag actttgacca taccaaaatg
    11341 ggcagataag ttgggacgag aaatgggact taacttttct cagactttga cagacgctat
    11401 tgcagataag aaagttcaag cctaagatta agcgtggtat cgtggtaata gtcaataaaa
    11461 aagcacgtcc acttgtgcta attactcgcc tattgatttt atagatttat tagccctttc
    11521 gagggctttt tatattgatt tttatgagaa atgaagaaat cagactttta agaaaatcac
    11581 tgataccaag ggtttaaatg aggtaatatg gtataattag gacataaaat aattttgtgg
    11641 taagatggta gtatctattt tagcatattt ccgagcaatc ggggcgatta aagagtcgca
    11701 tagaaagagg acaaaatggc aacatacgga tttttagatg ttttagagga agagttggac
    11761 aagaactttc cctttgactt tgagattagc tgggacaaac gcaaccatgc ggtagaagtg
    11821 agttttctat tggaagcgca aaatgctgca ggtgtggaga tggtggatga agacggagag
    11881 gtttcatcag atgacattct ttttgaggaa gcggtccttt tctacaatcc tgccaagtca
    11941 acagtcaatg aggaagacta tttgactgtt attccttacc tgcctaaaaa aggattttcc
    12001 cgtgaatttt tagcttattt tgcgcttttc cttaaagata ctgctgaggt tgggctagat
    12061 gtcctcatgg actttttgga agacccagaa gcagaggaat ttgttatgga atggaaccaa
    12121 gaagtctttg aagaaggaaa agttggcttg gaagagggag aattttatcc ttatccaaaa
    12181 tactaggagt tggttggagg tgttatgaag aaaattggga cttatttggt ttatgtgcta
    12241 gctgttgtct ttattatgct agcttttgct tgtggaacaa tcgcatttgc agagttgggg
    12301 tattccgcag ttttagcctt tacttttggt tatgccttcg ctcttctaag catgtattta
    12361 atctttattc ttcatgagct gggtcatgct ttttgtggct acttgacagg ctatcggctg
    12421 gtggcttttg gattaggaca ttttattttg accaaaaagt caggcaggtt tcatcttagt
    12481 agaacagcca ttctgaaaaa tgttggtgct cgatacattg gtttaaaaga ggatgaaagc
    12541 gatcaaagaa tcatcctgat gctttcagga ggcttgatgg ttcatctcgg cttgatatta
    12601 ttggcgatat tgtttggatt tttgacaaga agctggtatt ttgcagggac ttggattttt
    12661 cttaatttat ctttcttcct aaataacatt ttgccagccg acatcaccga tggagcaaaa
    12721 atttgggaat tactacaaca ccctgaaaat accaaatacg cctacctggt attgagacat
    12781 tctgctcaaa ctttgctggc tcctcaagaa tatgatttga aagactttgt tcaagcagtt
    12841 cctgaggatg cacgagggag ttttgcggat ggtgtattag gtatgcaagg tgaagtttcc
    12901 attttggaag ggaaggaaga agtagctaaa cagcagtttc aagcattact tgagaggaca
    12961 actactccga tgatgcagac agttgcccaa ctatccctgc ttcatatcgc cttgttggaa
    13021 ggagattttg agcaagcgga gcaatatgct agtattcgac aggtcaaatc gtttctgtct
    13081 ctcaaactgt ccaatcttca agtgatacaa gcttggtatc aatttaaggt aaagaaagat
    13141 gtagttcaaa ctcacaaggc tatgaagatt gctagacaga aaatgaatag cagccggatg
    13201 ttacgggatg agaaaagata ttatgaaaac tggttagccg agctggaaaa ggaattagcc
    13261 gaaggagtct aatatggaaa tagagatttc tggtttcaca ggttgcaaga ttgctttgtt
    13321 ttgtggggat aagcttttga ctatcttacg cgatgataag gcaagcattc cctgggccaa
    13381 tatgtgggaa ctgccaggtg gtggacgtga aggtgatgaa agtccttttg agtgcgcggc
    13441 gcgtgaagtt tatgaagaac tgggcattca tctgactgaa gattgtctgc tttggagtaa
    13501 ggtttaccca agtatacttt ttgcagacaa acagtccgtt tttctagttg gtcagttgac
    13561 acagaaccag tttgacagta tcgtatttgg agatgaagga cagggctatc agctgatgaa
    13621 tgttgaggaa tttcttagtt ccagtcaagt tgtgcctcag ttgcaagaga gattaaaaga
    13681 ttatttaaaa gtaagtgatt agaaaggatg gttcagttaa atttctaaac tgaacccgcc
    13741 ctaaatactg tgccaaaaag ataaacttct cttagacaca agcgtcttca gagaatttcc
    13801 tattttggtt ttgtgtttta cgggcttggt atcttaatga tggaaacatg gcaagagtta
    13861 aaagttacag tgaagcgtga gggagaggag ttggtttcca atctcttgat tgagctggga
    13921 gcgcaaggtg ttgcgattga agacagcatg gactatgtgg gaaatgtgga tcgctttggc
    13981 gagattttcc cagaggtgga gcagcaagaa gaaatcgtag tgacagccta ctaccctgac
    14041 acggtggatg tgacagtggt tgaggcggac ttgcaggctc gcatatcaga attgacggat
    14101 tttatggatt cgggagagtt aaaaataggt acgactgcct tggctgagga agactgggca
    14161 gacaactgga agaaatacta tgagccagct cgtatcactc atgatttgac catcgttccc
    14221 tcttggacag actatgaggc gactgcggga gaaaaaatta tcaagctgga tcctggcatg
    14281 gcttttggta ctggaaccca cccaactacc aagatgagcc tttttgcctt ggaacaggtt
    14341 cttcgtggtg gcgaaacggt gctagatgtg gggactggtt caggggttct ctctattgcc
    14401 agctcgcttc tgggggctaa agaaattttc gcctatgacc tggatgatgt ggcggttcgt
    14461 gtggctcagg aaaatattga gctcaaccct tgtatggaaa acatccatgt agcagcagga
    14521 gacttgctta agggtgttga gattgaggca gatgtgattg tagctaatat cttggcggat
    14581 atcctcgttc atctgacaga cgatgcctat cgtttggtta aggacgaagg ctacctgatc
    14641 atgagtggga ttatcaagga caagtgggac atggtgcgcg agtcggctga gttatctgga
    14701 tttttccttg agacccacat gattcagggg gaatggaatg cctgtgtctt caagaagacc
    14761 aaggatatct ctggtgtgat tggaggctag catgcagcag tattttgtaa aaggcagtgc
    14821 tatctctcct gtcactatcg aggacaagga aaccagtaag catatgtttc aggttatgcg
    14881 cttgaaagaa gaggatgagg ttaccttagt ctttgatgat ggcatcaagc gcttggcgcg
    14941 cgtgctggat atggaaaatc gtcagtttga gttgatccaa gaattaaatg acaatgtgga
    15001 actaccagtc caagtgacca tcgcatctgg atttcccaag ggagacaagc tggagttcat
    15061 cgctcaaaaa gtaaccgaac tgggtgctag ccaaatctgg gccttttctg cagattggtc
    15121 agttgccaag tgggatggca agaaattgga taaaaaagtt gaaaaactag aaaaaattgc
    15181 ccttggagca gccgagcaaa gcaagcgtaa tattgtacca agtattaaac ttttcgagaa
    15241 aaaagcagat tttctagctc agctggacca gtttgactct atcatagtag cctatgaaga
    15301 atcagctaaa gaaggagaag ccgctgcgct tctgcaagca gtcactggtc ttgaaacagg
    15361 agccaaactg ctctttatct ttggtccaga aggcggtctc tcacctgcag aaatcgaaag
    15421 ttttgaagct aaaggagccg ttttggcagg cctaggtcct cgtattttgc gagcagaaac
    15481 agcaccgctt tacgctttat cagcccttag tgttttagta gaattagaga aataagagga
    15541 agaaaatgga acaaaaacac cgttcagaat ttccagagaa ggaactctgg gacttaacag
    15601 ccctatacca agaccgtgag gatttcttgc gtgcaatcga gaaagctcgc gaagacatca
    15661 accagtttag ccgtgattac aagggcaacc ttcacacttt tgaggatttc gagaaggcct
    15721 ttgcggaatt ggaacagatc tacattcaga tgagccatat tggcaactat ggttttatgc
    15781 ctcagacgac ggactatagc aatgacgaat ttgccaatat tgcccaagct gggatggaat
    15841 ttgaaacaga tgccagcgta gccttgacct tctttgacga tgccttggtg gcagcagatg
    15901 aggaagtctt ggaccgtttg ggtaaattgc cacatttaac agctgccatt cgtcaggcta
    15961 aaatcaaaaa agcccactac ttaggggcag atgtggagaa ggccttgaca aatctcggtg
    16021 aagttttcta cagtccgcag gacatttata ctaagatgcg agctggggat tttgaaatgg
    16081 ctgactttga agcccatggc aagacctaca aaaacagctt tgtgacctat gagaatttct
    16141 accaaaacca tgaggatgct gaggttcgtg agaaatcctt ccgttccttc tcagagggac
    16201 ttcgtaagca ccaaaatacg gctgcagcag cctatctggc tcaggtcaag tctgaaaaac
    16261 tcttggctga tatgaaggga tacgactctg tctttgatta tcttctagct gaacaagaag
    16321 tggaccgtgt catgtttgac cgccagattg acctcatcat gaaggacttt gcaccagtcg
    16381 ctcagagata cctcaagcat gttgccaagg taaatggtct tgaaaagatg acctttgcag
    16441 actggaaatt ggacttggac agcgccctga atcctgaagt gactattgac gatgcctatg
    16501 atttggtcat gaagtcggta gaacctttgg ggcaagaata ttgtcaggaa gttgctcgtt
    16561 accaagaaga gcgctgggtg gactttgctg ctaacagtgg caaggattcc ggtggttatg
    16621 cggcggaccc atatcgcgta cacccttatg tcctcatgag ctggacaggc cgtttgagcg
    16681 atgtctatac cttgattcat gaaatcgggc attctggtca attcatcttt tcagacaatc
    16741 atcaaagtta cttcaatgcc catatgtcga cctactatgt tgaagcaccg tcaaccttca
    16801 atgaattgct actcagtgat tacttagaga accaatctaa tgacccacgt caaaaacgct
    16861 tcgctctggc tcatcgcttg acagacacct acttccataa ctttatcacc cacctcttgg
    16921 aagccgcctt ccagcgtaag gtgtatacat tgattgaaga aggagaaacc ttcggagcaa
    16981 gcaaactcaa cagtattatg aaggaagttt tgacagattt ttggggcgat gccattgaaa
    17041 tcgacgacga tgcagctttg acttggatgc gccaagctca ctactatatg ggcttgtata
    17101 gttacactta ctctgctggt cttgtcatct cgacagctgg ttaccttcat cttaaaaact
    17161 cagaaactgg agctgaagac tggctcaatc tcctcaaatc aggtggtagc aagacaccac
    17221 ttgagtcagc catgattatc ggtgctgata tttcaacaga caaaccactc cgtgatacca
    17281 tccaattctt gtctgacaca gttgaccaga ttatcgccta cagtgctgag ttgggggagt
    17341 aaggagatag aaaaattttt tagaatgatg tttatgggct tgttaagcgt cattctattt
    17401 gtcttagttg tagctatttt caaaaatgtc gttgaaggtc gtgatgttaa atttgaactt
    17461 actgtagaac tggtattgat agttatttac gtcattttat atcagattgt atttaattga
    17521 gaattcaata ttgagtcatt taagactgcc tttttgaaca gttgctagaa atgtagaggt
    17581 attgaccatg tatcaagatt tactaagaaa aatagcagaa gaaaaaccaa attataacca
    17641 ggaagaaatc cagtggttgt ttgatcattt gggaaatcct tctccagaaa ttcgtaatgt
    17701 ccttttaaat caaggcttgc actatctttc aaaagaaaag gatacaacag gtttctcaag
    17761 tcagtatggt tgggttcatg cttttgcaca tggagccgat ttactgacag aggtggtttg
    17821 tcatccagac tttcctataa acagaattca tgaagtattt gacatacttg gccaactatt
    17881 taaaagaatg tcgattcgct ttacagatga tgaggattgg cgtttagcaa gagtgatcta
    17941 tgaacctatt ttacaaggga agttggagca agaacaagta gcttcttgga taaaaactgt
    18001 tgattttccg atagaagaaa gggaggattt ttacaaattt tccaacttta gatcctgtct
    18061 ggtggaagtc tatgtccaac ttgaccagag aaatagttta caagatgagt tgaaagaagc
    18121 tatccagtct tttcaatact agagattagc taatagttct atgattttca aaaaatttcc
    18181 aatcaatttt cttgaaaccc tttcctactt ttgatagact agtatctagt ttttgaaaaa
    18241 aggagaaaga aaatgaaaaa atttgttgct gagttaatcg gtacgttcat gcttgtattc
    18301 gtcgggacag gagctgttgt ttttggaaat ggtcttgatg gccttggtca ccttggaatc
    18361 gcctttgcct ttggtttggc aatcgtggtg gcagcctact caatcggaac tgtttcaggt
    18421 gctcacttga acccggctgt ttcgattgct atgtttgtaa acaaacgttt gtcatcttca
    18481 gaacttgtaa actacatcct tggtcaggtt gttggagctt tcatcgcttc tggcgctgtc
    18541 ttcttcctct tggctaactc aggtatgtca actgctagtc ttggtgaaaa tgccttggca
    18601 aacggtgtca ctgtctttgg tggtttcttg tttgaagtca tcgcaacttt cttgtttgta
    18661 ttggttatca tgactgtgac ttcagaaagc aagggcaatg gcccgattgc tggtttggta
    18721 atcggtttgt cattgatggc gatgattctt gtcggattga agattactgg actttcagta
    18781 aacccagctc gtagcttggc accagctgtc ttggtaggcg gcgcagccct tcaacaagtt
    18841 tggattttca tccttgcacc aatcgctggt ggagttcttg cagcccttgt tgcaaaaaat
    18901 ttccttggaa cagaagaata attgaaactc aaaaagcctt gctcctcatc ttgaggaaca
    18961 gggctttttc gtatgatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc
    19021 gtaggtatgg ttactgactt cgtcagtttc atctacaatc tcaaaacagt gtttt
//
LOCUS       DAVLTT010000038        18760 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLTT010000038 DAVLTT010000000
VERSION     DAVLTT010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18760
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.038"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(95..748)
                     /gene="phoU"
                     /locus_tag="VYN15_001424"
     CDS             complement(95..748)
                     /gene="phoU"
                     /locus_tag="VYN15_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1452730.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(760..1518)
                     /gene="pstB"
                     /locus_tag="VYN15_001425"
     CDS             complement(760..1518)
                     /gene="pstB"
                     /locus_tag="VYN15_001425"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1452731.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            complement(1531..2334)
                     /gene="pstB"
                     /locus_tag="VYN15_001426"
     CDS             complement(1531..2334)
                     /gene="pstB"
                     /locus_tag="VYN15_001426"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1452732.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYGKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(2345..3229)
                     /gene="pstA"
                     /locus_tag="VYN15_001427"
     CDS             complement(2345..3229)
                     /gene="pstA"
                     /locus_tag="VYN15_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1452733.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(3219..4136)
                     /gene="pstC"
                     /locus_tag="VYN15_001428"
     CDS             complement(3219..4136)
                     /gene="pstC"
                     /locus_tag="VYN15_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1452734.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(4136..5014)
                     /gene="pstS"
                     /locus_tag="VYN15_001429"
     CDS             complement(4136..5014)
                     /gene="pstS"
                     /locus_tag="VYN15_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV1452735.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(5588..6892)
                     /locus_tag="VYN15_001430"
     CDS             complement(5588..6892)
                     /locus_tag="VYN15_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV1452736.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(6893..7666)
                     /locus_tag="VYN15_001431"
     CDS             complement(6893..7666)
                     /locus_tag="VYN15_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV1452737.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(7656..7934)
                     /locus_tag="VYN15_001432"
     CDS             complement(7656..7934)
                     /locus_tag="VYN15_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV1452738.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(7934..8335)
                     /locus_tag="VYN15_001433"
     CDS             complement(7934..8335)
                     /locus_tag="VYN15_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV1452739.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(8542..9159)
                     /locus_tag="VYN15_001434"
     CDS             complement(8542..9159)
                     /locus_tag="VYN15_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV1452740.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLCLKSRRK"
     gene            complement(9149..9922)
                     /locus_tag="VYN15_001435"
     CDS             complement(9149..9922)
                     /locus_tag="VYN15_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV1452741.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(9933..10670)
                     /locus_tag="VYN15_001436"
     CDS             complement(9933..10670)
                     /locus_tag="VYN15_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV1452742.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(10675..11805)
                     /locus_tag="VYN15_001437"
     CDS             complement(10675..11805)
                     /locus_tag="VYN15_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV1452743.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(11889..12278)
                     /locus_tag="VYN15_001438"
     CDS             complement(11889..12278)
                     /locus_tag="VYN15_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1452744.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(12294..12677)
                     /locus_tag="VYN15_001439"
     CDS             complement(12294..12677)
                     /locus_tag="VYN15_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV1452745.1"
                     /translation="MLEVAYILVALAVIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(12678..13466)
                     /locus_tag="VYN15_001440"
     CDS             complement(12678..13466)
                     /locus_tag="VYN15_001440"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV1452746.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(13459..14394)
                     /locus_tag="VYN15_001441"
     CDS             complement(13459..14394)
                     /locus_tag="VYN15_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV1452747.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(14524..14700)
                     /locus_tag="VYN15_001442"
     CDS             complement(14524..14700)
                     /locus_tag="VYN15_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV1452748.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(14840..15547)
                     /locus_tag="VYN15_001443"
     CDS             complement(14840..15547)
                     /locus_tag="VYN15_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV1452749.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            15698..16726
                     /gene="queA"
                     /locus_tag="VYN15_001444"
     CDS             15698..16726
                     /gene="queA"
                     /locus_tag="VYN15_001444"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV1452750.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
     gene            complement(17387..17776)
                     /locus_tag="VYN15_001445"
     CDS             complement(17387..17776)
                     /locus_tag="VYN15_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1452751.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(17830..18522)
                     /locus_tag="VYN15_001446"
     CDS             complement(17830..18522)
                     /locus_tag="VYN15_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1452752.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYNV
                     DGKSGQVTESTLSQKKDSQTRVVKKGTKPQVLVQEIPIETEYLDGPTLDKSQEVEEVG
                     EIGKLLLLQSIL"
BASE COUNT         5556 a         4317 c         3423 g         5464 t
ORIGIN      
        1 gttttttaaa tttttatctc aaaaatattt tttcgttcaa aaaaaggagc catcagttga
       61 tttcaagctc ctttttatac agaattaaac tattttatag ttcgacaatc ttacctgttt
      121 caaagtagac aacccattca cagatatttt tagcatagtc accgatacgc tccaagtagg
      181 aaataacttg gaaataatca cgacccgtaa caatggcttc tggatttttc ttaatctctt
      241 cagtcgcaag gtcacggata gtttcaaaat agtggttaat ttgctcatcc atggaggcca
      301 cccggtatgc gtcgtcaaca gaaccattaa gataaagatc aagtgctgct tcaacaacgc
      361 ttttaacttc acgtcccatt tttttaattt cttcctctac agctggaatg cgctcttccc
      421 ccttcatacg gatggttgcc tgagcaatgg ctacagcgtg atcccccata cgctccacat
      481 ctgatacagc cttaaggaca gtcaagactg tacgcaaatc ttgagagact ggttgttgga
      541 gtgcgatcat ttcaaatgat ttcttttcca gtttcacttc gtattcattt acttctgcat
      601 catcttcgat gacctctttt gccaggtcac ggtcatgcgt gacaaaagca cgtaccgtac
      661 gattgatttg tgagagcact tcttgtccca tagcgtagaa ctggttatgt aatttctcta
      721 aatcttcttc aaattgagat cgtaacatct ttcatctcct tatccaaatt ttcctgtaat
      781 atagtcttcc gtttccttgt gttggggatt aaggaacatc tgcttggtat cattaaattc
      841 aatcaaatct ccatctagga aaaatcctgt cttatcagag atacgtgaag cttgctgcat
      901 ggaacgggtt accagaagca tggtgtactt gtcttttaga ccatacaagg tttcctcaat
      961 tttaccagct gaaatcggat ccaaagccga agttggctca tccaagagga tgattttagg
     1021 actagttgcc aagacacggg ccacgcagac acgctgctgt tgaccacctg acaatccaat
     1081 agctgaatca tatagacgat ccttgacctc atcccagata gaggcacctt gcaaggcttt
     1141 ttctacggct tcatccagaa cctgcttatc cttaattcca ttgatacgaa gcccgtagac
     1201 aacattctca tagatagtca tagggaaagg attaggttgt tggaaaacca ttccgatttc
     1261 cttacgtaat tcaaccgtat ctgtacgcgg actgtagatg ttgtgaccat tgtacaccac
     1321 ggatccagtt gtggtcacct ctggattgag atctcccatg cggttgagag acttgaggag
     1381 ggttgacttc cctgatccag atggaccaat caaggctgta atttccttag gttggaaaga
     1441 tagggaaaca ctattcaaag ccttcttttt attataataa acggacaggt ctgatacctg
     1501 taaaatcgca tctgtcatac ggtttccttt ctaaccaaag tgaccagata catagtcatt
     1561 ggtggactgt agcttggcat tttggaaaat agttgcagtc ttgccatact caatcaaatc
     1621 acccaagtaa aagaagcctg tatagtcact tgcacgagca gcctgctgca tattatgcgt
     1681 tacaatgatg atggtaaagt ttttcttgag ctcaaacatg gtctcttcta gttgcatggt
     1741 cgcaatcgga tccaaggctg aggctggctc atccattaag aggatatctg gcttaacaga
     1801 gatggcacga gcgatacaga gacgttgttg ctgaccacct gataaggtca aggctgactt
     1861 gtggagatcg tctttaacct gatcccaaag ggcagcctga cgaagggagg tttctacgat
     1921 ttcatctagg acttgcttat ccttaactcc agcacgttca tgcgcaaagg taatattacg
     1981 gtaaattgac ttagcaaatg gattggggcg ttgaaaaacc attccaatgt gtttacgcat
     2041 ttcataaacg ttgatttctg gacggttgac atcaattcca cgatagagaa tctgcccagt
     2101 tactttagca atatcaatgg tatcattcat gcgattgaga ctgcgtaagt aggtagattt
     2161 ccccgatccc gacggaccaa tcaaagctgt aattttattt ctttcaaatt gcatatcaat
     2221 ccccttaatg gattcatttt taccatagta aacatggaca tccttagtag aaagggctac
     2281 tttttcttca ggaaaggtaa ggatatgctt ctcatcccag ttatatgttg acatggcttc
     2341 tcctttaggc agcggttaat ttcttgtgta gatagcttcc gaacttacga gctccaaagt
     2401 taaaaatcag gataaagatc aggagcacag cggcagaacc tgctgataca atggttccat
     2461 ctggaatagt gccttcacta ttgactttcc agatatggac agccaaggtt tctgcttgac
     2521 ggaagataga gatggggcta gtcacactga ggatattcca gttagaccag tcaagagctg
     2581 gcgccgattg ccctgctgta tagatcagag ctgcagcttc gccaaagata cgaccagatg
     2641 ccaaaacgac acccgttaca atacctggaa gcgcttctgg aataacaaca tgaaccactg
     2701 tctcccagcg agaaatccca agagccagac cagcctcacg ttgggtatgg tgaacgtgtt
     2761 tcaaactatc ctctacatta cgcgtcatct gaggcaagtt aaagactgtc aaggccaagg
     2821 cacctgaaat gattgaaaat ccatactcaa actggactac aaagatcaag taaccaaaga
     2881 gacccaccac cactgatggt aaagaggaca agatttcaat acaagtccgc acaaagttgg
     2941 taacaggacc ttttttagca tattcagcca agtaaatccc agctcccata gaaagaggta
     3001 cagaaataat caaggtaatg accaatagga aaaaggaatt gtaaagctga atgccaatcc
     3061 caccacctgc ttgaaaagca gaagaccttc cagtcaagaa agaccaagag atatggggca
     3121 agccccgaac caagatatag agaatcaagg aagccaagat tgtcacaatg atgctagcaa
     3181 tcgtatagag gacagctgtt gcaagtttat ctaatttctt agcgcgcata atttttcttt
     3241 cctctttctt tcgtaatcaa tttaatcaca ctgttaaaaa ctaaactcat caagagcagt
     3301 accaaggcca gtgaccagag aacattatta tttacagttc ccatgacagt gttcccaatt
     3361 cccatagtta atatagaagt taaagttgca gctggtgtgg tcaaggaagt tgggataaca
     3421 gctgagtttc cgacaaccat ctggatagct agagcctcac caaaggcacg cgccatccca
     3481 aagaccactg cagtgaaaat accagaacgg gccgccttca agatcacacg ccagatagtc
     3541 tgccagcgag tggctcccat agcgaaactg gcttcacgat aataacgagg aaccgcacgc
     3601 aagctatccg ttgtcataaa ggttacggtc ggcaaaatca tgacaaagag gacggaaatc
     3661 cctgacaaaa tcccaaaacc agtcccacca aagacactgc gaacaaaggg aacgacgact
     3721 tgcaagccaa taaatccgta cactactgaa ggaatcccaa ccaggagttc aatagctggt
     3781 tgcaaaatct tcgccccttt tggtgatact tcggtcataa aaactgctgc accaatagca
     3841 aagggtgttg cgataagggc tgagagaatg gtaacgataa aggaacccaa aatcatagga
     3901 agggcaccaa attctttact agaaggattc caagttcctc ccaaaagaaa gtcaaagata
     3961 ttcacaccat tgacaaagaa ggtcgacaag cctttttgcg ctacgaaaac caaaatcatg
     4021 gccacaagga tgactatcaa agaaagacag gcaaaggtca aaccttttcc taatttctcc
     4081 agacgagaat tctttgatgg aagcaacatt ttcttggcta attcttcttg attcattatt
     4141 gtctcccttc caacactgtc acagttccgg cagcatcttt ttcaaccttc atttccttaa
     4201 tcggaatata cttcaatcct ttgacaatcc cttcttgggt ctcatccgag agaacaaaat
     4261 tgagaaattc tgcagccaac tcattgggct gccccaatgt atacatatgc tcataagacc
     4321 acaagggcca attattgcta cttatatttt ctggacttaa gtcatagcca ttcaacttca
     4381 tgcttttgac cgaatcatct atataggtaa gagataaata agagatagct cctggacttt
     4441 ttgatacgat tgattttacc gctccatttg aatcctgctc ctgactttgc atggcagact
     4501 gaccttccat aatgacagta tcaaaggtag cacgagagcc agagccggct gcccgattga
     4561 taacagagat gggtaagtcc ttaccaccaa cctctttcca attggttacc tcacctatga
     4621 agatttgacg aagttgctct gtcgttaggt tatcaacatc aacctcctta ttgacaatca
     4681 gagccaagcc agctaccgcg accttgtggt caacaagagc agaagcatca attccgtctt
     4741 tttcctcagc aaatacatct gagtttccta tatcaactgc cccagactga acctgggaca
     4801 agcctgtacc agaacctccc ccttggacat tgaccgtttt tccaacatgg atcgtgccaa
     4861 attcatctgc cgctacttca accaagggtt gcaaggcagt tgagccaaca gccgttatgg
     4921 attctccacg atcaatccag ctagcacagc ctactaaaca agccgtcagc caaaaagcga
     4981 taagagacag agcaagcttt tttctttttt tcactgtttt tctcctcgaa aataattatg
     5041 aatactgtga attttttaag tagttcttta tgagttgacg catgaattct taccaaattt
     5101 ctgcgcaatt gattatttat ataatatagg ctatattact ctttcctaac ctcctttttt
     5161 catatgtgga taaaatctct tgtctatccc ttcccccatt gtcacccatt atagtcattt
     5221 cgtgtctctt tttccccttt ttaatgcaag ggaaattact cttcttagat gataatccaa
     5281 aagctagaaa ggtatctcaa acctctctac tctcccagac tagtttacaa ctaaaaggaa
     5341 aagattctat tttatgagaa atctagttta caagcggtaa gaacgctaat aactaaactt
     5401 cttgtactct ttgaaaatct cttcaaacca gtgttttgag ctatctatgg ctagcttcct
     5461 agtttgctct ttgattttca ttgagtagta aaactacatg taatggcaat caagatatca
     5521 agaatcatcc tactaaaaaa atccatactt tcactataac atagaataag atatttgact
     5581 agcattttca tttgaatctg aggccttttg gaaaataatt tttcaaaaca tttccagtaa
     5641 cctttgcaaa gcccaagcca ttgcctttaa ccaaaacttg gtaccaacca tttggcagac
     5701 tttctgccag ctgaacgatt tctccagccg catacttgac aaacgcttct tggccaattt
     5761 caaccgactg ttcgacctga ctcggtttca aggctaaacc aagagcgaaa ctgggctcaa
     5821 agcgtttctt cttaaaagtg cccagatgca gtccattgcg agcaatcttg agcttcccta
     5881 aatctggcaa aagttctggc aagagataaa gctggtctcc aaaagtctgc aagatacccg
     5941 gtagattgac cttcaaatgg ttttgggcaa attcctgcca caaggcaact tgttcacggc
     6001 tgaggttact cttacttgcc ttaaatttag gagctggatt gttaccctta aactgtagat
     6061 gggcaacaaa ctgaccctct cccttaaact gatgaggata catccgagcc gtttctggca
     6121 ggtcaatacc agctaccatt ccattgatat gctctactgg caacaagtca aaatcatact
     6181 cttccagcaa ccaattgaca atctcttcgt tttcctcggg tgcccaggta caggtcgaat
     6241 aaaccagacg accaccttca gctaacatgg tcactgcatc ctccagaatt tctctttgca
     6301 agctagcaca ttgactcgga taatctaagc tccaatagtc catagcatca ggttgcttac
     6361 gaaacattcc ttcaccagag caaggggcat caagaacgat taagtcaaaa tagcctttaa
     6421 agaccttgac caagcggtcg gcagattcat tggtcaccac gacatttgtc gctccaaaac
     6481 gctccatgtt ttcaaccaaa atcttagccc gtttgcttga aatttcattg gaaacaagta
     6541 gcccctcccc tgctagatag gctgccagtt gagttgattt gccccccggt gcagcagcca
     6601 agtccaagac cttcatacca ggactgggtt gggctacttg agccaccatt tgagcagcag
     6661 gttcttgcga ataaactaaa cctgtagcat gctcaggcga tttccctgaa accttcccat
     6721 agtggcccca aggggtttga gtaatggcat cagaaaagga aagttgctct tcttttaagg
     6781 gattgacccg aaaggccgaa accgcttcct cctcaaaaga ggcaagaaaa tctcttgcct
     6841 catctcctag tatttcttta tatttttcaa caaatccttc tggaaatttc atttaagttc
     6901 ttttcctttc gtaaatatag gactgaattt cctcctgcat ctcaagaggc accatcatga
     6961 ccggctgtct ggtttgaaaa tcaggagctt caccaaaaag ggtcacaacc cgatagccca
     7021 gactttcccc taaaatacta gctgcggcat aatcccatgg ttgcagatag gtgagatagg
     7081 tcaacaaatg ccctgacaaa atcttggcaa aactaatggc cgcacttcca tagacacgaa
     7141 caccaagaac cgctcggctc aaatcagcca gcccccattc attggtttcc agcataccac
     7201 tattccctgc aatgagaaaa tctccaagtg gtttagtttt aaaaggagct aggggcctat
     7261 catttagaca aactggaaat tccccaccac cgtggtaaca atcccctttg accacatcat
     7321 aaatcagacc aaactgtccc tgaccatttt caaaataagc catcataaca gcaaaatctt
     7381 cctgctgggc tacaaaatta ttggtaccat caatgggatc aatgacccaa accttgccct
     7441 cttgaaccga ggctcgcaga caaccttctt cagcacaaat cttatcctca ggataacggg
     7501 acaaaatctc accaaccaag agttcctgaa cttctttgtc cagtctggtc accaaatctg
     7561 ttggagagga cttggtttca acacgcaagt cttcctgcat atggtcaaga atgtactggc
     7621 ctgctttctt aacaagctct ttagcaaatt caaatttact ttccaagaga aatctttcct
     7681 tccccttttt ctttggcagc ctgaactgct cggtaaagtg aatagccact aaccgtttca
     7741 aattctcgtc ccaaacgttt ctcttcgctc ttgcttggca cgaccgcttt gaatccctta
     7801 taggagtcca gtaacttttt agcctctact ttgccttcat aggcagcttc aacatcatta
     7861 aaaaaagaaa gcactgaagc aagttcttca gtgctccacg acaaatctag tgggtaacta
     7921 tactgtttgt tcattaacta ataccagctc tcattcttgc ttcttttagt tcttgcttac
     7981 gataactacg agggagaaaa gcacgaatct catcttcatt aaaaccgatt tgcatacgct
     8041 tggcatcaat aataattgga cgacgcaaaa gactaggata ctgctcaatc aaatgaagca
     8101 attccgatac cgaaatactc tctacatcaa tattcaattt ttgaaaaatt tttgaacgag
     8161 ttgaaatgat gtcatcagta ccattttcgg tcaaggaaag gatgtgttgc aattcttttc
     8221 ttgttaaagg actggtcata atattgtgtt ccacaaaggg aaccttatgt ttttctaacc
     8281 aggccttagc cttacgacat gatgtacagc tcggtgatag aaatagtgta atcatgcttt
     8341 tctcttctta tctatacttt gctacttcta ttatacaaaa aaataaggcg cttgactagg
     8401 gatttttaga aaaaagccta ttttttcagg aaaaataggc tgtttgcgaa cgattgacac
     8461 aattggattt ggttaattca ctcttaacga tggttttaaa cgatatatat atttatatgt
     8521 aaattaaaaa catctttcct ttcacttcct acgacttttc agacacagat agccaaagaa
     8581 gttttcatag agggcaaaaa agaggaggaa ggcatgaaga aagaaggtct ctggcaaaat
     8641 cataataaca ggatccttgg ctggatcaaa aagccaggta tcatctccca caaagagaat
     8701 ttgatggaaa agagtaaaga attggtcaaa accaatcaaa actcccccaa gtccaatcat
     8761 tacaggtaaa actactagag ccaggagact ttttcgataa agagacaaaa agtccttttt
     8821 cacaatccta ttgacaaaga catagaaact tggcagtgtc actagagcta ctagctgaac
     8881 caaatgaaag agattcttga ccactgcgaa atggtgcaga ccagctgctg acgaacgaaa
     8941 atcaggcatc tgtaagacct gactaaaagg attggtcaga taattcatca agatatgaaa
     9001 attgtattga atggtttctg gttttagata gactcgattc gttaagttta gccactgaat
     9061 ctccatagga tagaaaatcc aagccagata aatggtcaga aggatggaga gggagaggag
     9121 aaagagcata gagccccaaa agatcaattt agttttcatc aaaatcccac tccgcaaggc
     9181 tagaaaccac atgtgtcggt gcgattggca ggccagctac ttcttctgcc ttagtaaaac
     9241 ctgtcgtcac caagagcgtt ggaatgccat tgtcaatccc agcccgaata tcagtcaaat
     9301 aattgtcccc aaccatgatt aactcttcac gttccaaacc taagtgctca accgccttgt
     9361 ccataatgat ggcatttggt tttccgatat aaaccggctt cactcgtgtc gctacttcaa
     9421 gcagcgtaat cagtgagcca gcacctggca aaagaccgcg ttccgtcggg atgttgaggt
     9481 caggattggt tccgataaaa tgggcaccct tttgaatagc aagagttgct gtggcaaatt
     9541 tttcatagtc gacttgccaa tccagaccaa ctaccacgta ggcagggttt tccttgtctt
     9601 ccacataacc agccgccttg atggcttcct tgagtcctgc ttctccgacg acatagacag
     9661 tcttttcaag ccccaaatca ttcatatagt cgatggttgc caaagtcgct gtgtagacag
     9721 tcgatagagg cgtatcgata ttaaaattct gagccaacat ctccttaaca ctctctggag
     9781 tgcgggttgt attgttggtt acaaagagat agggaatgtc ccgcttttgc aattcatgaa
     9841 caaaagtctc tccagcaggg attcggtctt tccccttata aatggttccg tctaaatcaa
     9901 ttaaatagcc tttatatttc atctatttct ccctaaacct tttttatttc ttgccaagta
     9961 atgattgctt gggcattgat aaccccatca cttgtaattt catgcttgct ttccagtcca
    10021 gtccgttcaa cagccgatgt aatcacccca cctggtcgaa cttccttgac atacttgagg
    10081 ttgattttct tgggaatata gtgggtcaaa aaatccgctc ccatgacctc aaaaatccag
    10141 tccaagtatt tactgttatt gacatgacca ttcatatcca agtcgtaaaa acgaacatgg
    10201 taatccttgc tgatcggctc ttccaaggat tcatacttcg gtccacggat aagtttttta
    10261 tcaaaatcag actggtaagg agccacaatc tcaggttcaa cagcatggac ttttcgactg
    10321 tcgcggtcca tgagaacaaa ggtcgccatc atatggatga gctcctgccc cgcttcatta
    10381 taaatagtaa agcgacggta gcaaaaaagt cgattgtagc tcaaggcttc cgtttcgatg
    10441 gtaatttctt ccgcaaaacg aggcaaacga accacctcaa tatcatattc tgcgataatc
    10501 cagaccagat tatagtcttc caaaatggcc ttatcactaa ctcccagttc aatcgattgc
    10561 atccctgaaa cttgcagtga cagcaaaatc acatctggaa gtttgatatg accgttcata
    10621 tcagccatat caaaaggaat tttcattttc atttgataag ttaagcccat gatcctactc
    10681 caaaataaat cgttctgcta cagtatctcc caaaaagaga cctctctttg tcatgcgaac
    10741 gtggtcaccc tcaatctgca tgaggccttg ttgaaccaag tctctgacaa tttctccata
    10801 aagtccagca aaagactgtc caaatttttc ctcaaatcgc gccatggaaa ccccggattt
    10861 cttgcggagt cccaagaaca tttcttcttc catttgctcc ttttgactca ggtgatcttc
    10921 tgtaatacaa gcattgcctt cctcaaccgc actgagataa tgacgaatgg gaccatgatt
    10981 tttatagcgt actccattga cataaccaga tgcccctgca ccaataccat agtattcagc
    11041 attgtcccag tacatgagat tatgacgact ttcaaagccg ggtttggaga aattagaaat
    11101 ctcataatgc tcaaaacccg ctcgctccag ctctgcaatg atgtactcaa acatctccgc
    11161 ttctagttcc tccttaggca gaggcaattt cccacgtcgc atccggttca taaagaccgt
    11221 atggttttct aaaatcaaac tatacaaact catgtgggga atatccaatc caatggcttt
    11281 agccacattt tcctttactt gctccatggt ctgaccaggc agagcataaa tcaaatcaat
    11341 ggagatgttg tcaaaaccag ccagtttcag gcgatcgata ttttcataaa tatccttctc
    11401 caaatgactg cgcccaatct ttttcaacat cttatcatca aaggtctgga cacctagcga
    11461 aacacgattg acagccgaat ttttcaaaac agctatctta tccgcatcca aatcgcctgg
    11521 attggcttca atggtcaact cttccaagac agacaaatcc aagtttttag tcaagccatt
    11581 cagtaacacc tccagttgcg gagccgacag ggctgtcggt gttccaccac cgatataaag
    11641 ggttgacaac ttttcaatat cataagaacg aaactcttcc agcagatgct ctaaatagct
    11701 gtcgactggc tgatttttga tgaagacctt tgaaaaatca caataataac aaatctgggt
    11761 acaaaatggg atgtgcacat aggctgacgt tggttttttc tgcatagtaa ttattatacc
    11821 acaaagacta gattccagat aaaaatcacc atccccagat acatagtccg tccggagatg
    11881 gtgatggttt attcttctgt tatatcaatc acaatctctt ctgagtcatc aagagcttcg
    11941 gctttttctt gccattgttc cttgagatta tttaattgat tttttgatgc ttctgtcgct
    12001 tgaaaagcat aggatttagc ttgagcaagt atactgtcca cagtgatttc acctgactca
    12061 acctgttctt ttgttttcag aacaaaatct gtagcctgct ccttaacttc tgtcagtttt
    12121 tcacagactt gctccttggc atactccgga tcttctctca aatcatctag aaaatcttga
    12181 gcctgactgc aaacttgttt gcccttatca cttgttaaaa acaaggcaag agctgcacct
    12241 gaaacggttc ctaaaaggat tgaggataat ttacccataa ggattctcct tttttatttt
    12301 ttgaaaaatt tacttgcaag acgaagagct gacagacttg caccagtctt gagtgttttt
    12361 gaaccagctg atgaagcttt cttgctcaag acacgcgcat ggtcattgag gtctgaaaca
    12421 gatagagata aatctgcaac agcactgaag agtggatcaa tcgtagccac cttgacattg
    12481 atatcatctg ccaagacatt gaccttagcc aacaactcat tggtgtgatg caaggtcaca
    12541 tccacatctg aagtcaaggt tttaatcgtc ttttctgttt catcgataac acgaccaagc
    12601 ttttgtacag taatgatcag atagaccaaa aagacaatca cagctagggc aacaagaata
    12661 tatgcaactt ctaacattta gttttcctcc tctgtaatat agtaaggggc cttctttcga
    12721 ttttgataaa taacgatcat tataccgaga ccgataaaga caactgacag ccattgggac
    12781 actcgaaggc cgaagaacat gagactatct gttcgcatac cttcgatgac catacgaccg
    12841 aaaccatacc aaatcaagta aaaggccgtg atatgacctc gtctgagact cttccatttc
    12901 cgtctaaaaa tcagaatcaa ggcaaagcca agcagattcc atagagactc ataaaggaaa
    12961 gtcggttgac ggtagctccc ctcaatatac atctggtcac ggataaagcc aggtagataa
    13021 tccagattat ccactgttgc accataagct tcttggttaa agaaattacc ccaacgcccc
    13081 aaactttgag caatcataac gctaggcgcc gcaatatcta gaaaatccca agtattgatg
    13141 agtttacggt cagcaaagat atagagcaca agagccccag ttatcaaacc accgtaaatg
    13201 gccaaaccac cattccaaat ggcaaaaatc tctcctaaat tctgactata gtaatcaaat
    13261 cggaaaataa catagtagag acgagctcct aaaatagcca agggaaaggc tactaagata
    13321 aaatctaaaa tatcgtctgg tatgatcttc tttctaggtg cttctttcat ggtcaaataa
    13381 accgcaagaa tcaagcctgt cacaatacat aaggcatacc aacgaatggc taggggtcct
    13441 agttgaatag caattggatc aagcattttg cacctcattt cgagctatga gacttgtcag
    13501 tcgttcgtcg aacaaacggg tagcatcaaa gcccatttcc ttggcacgat aattcatggc
    13561 agctgcctca atcacaacag agatattacg acctgtttta actggaatac gaatacgagg
    13621 aatggctacg ccagaaactt caagttcctc tgcattgttt ccaagacgat caaaggtctt
    13681 atgcgtatcg taattttcca aatagacagc aagctgaacc tgtgaagaat ccttgacagc
    13741 actcgcaccg tagagactca taacatcgat aataccaacc ccacgaattt caatcaagtg
    13801 tttcaaaatt tcagctggtt caccccagag agtaatctca tccttggcaa agatatcgac
    13861 acggtcatcg gctaccaaac ggtgaccacg tttgacaagc tcaagacctg tctcgctctt
    13921 accaattcca ctatctccct gaatcaagac gcccatccca taaatatcca tcaagacacc
    13981 gtgcacactg gtacgttctg ccaaacgaga atccagatag ctagataact ctccagataa
    14041 acgactggta gctgcacggc tggttaaaat agcaatctta cattctctag cagcctttaa
    14101 catctcctct ggaaccacca aaccacgggc aacaatgact gctggtgtct caggtagaaa
    14161 catttttttc aaaacttcat aacggctgtt ggaaggcatg ctgatcagat aagaccactc
    14221 cttcatcccc aaaagttgaa tccgctctgg tgtatagtag tcaaaatagc ctgtcatttc
    14281 aagaccaggt cgcgtaatat ccgctgtatt gatttccttt tcaagcaatt ctggttcacc
    14341 atagacaata tctagtctaa gcttttcaat cacttctttt actaaaaccg acatcatttc
    14401 ctccttcaaa tgaattcttc tctctattat atcaaattgt aggaggaagt ttcagatttt
    14461 tgcaggcttt ggagtattta tttaaaagaa aaaggactag atttctctag cctttcattt
    14521 caattagaat tttttacgtt tacgagctac ttctgattta cgtttacgtt ttacagaagg
    14581 tttttcatag aattcacgtt tgcgtgtttc ttgaagagta ccagctttag taaccgcacg
    14641 tttgaaacgg cgaagtgcgt cgtcaagaga ttcattctta cgtactactg ttttagacat
    14701 ttttttcact cccttcaagt tcaatatcta tttcattcta cacgtaaaag gaataattgt
    14761 caagcaaaaa tgcggtttaa ttttgatttt ttcttccatt tatacaagag ttgaaagcgt
    14821 tcaatagaac attgcttttt tatttttcga gtaagctaag cgcttcagca tctgcgatga
    14881 tggttacatc agggtgattt tggaggctac ttgcaggtag gttctcagtc actgggccag
    14941 atactgttcc ggcaatggct tctgctttcg actcaccata agcaaaaaga ataatagact
    15001 tggcatccaa aatgttttta atccccattg aaatagcttg ggttgggacg tcttcaatct
    15061 tggcaaagaa gcgagcattg gcttcgatag tagactggtc aagttctact agatgcgttt
    15121 gactgtcaaa tggagtacca ggctcattaa agccgatatg cccattgcga ccgattccca
    15181 agatttggag gtcaactgga tggtcagcca aaatttggtt gtagcgttca acttcagctt
    15241 cagcattgtc cttaacacca cgaggcaaga aactttcttt aaatggtttt tggttgaaca
    15301 agttttcttg catgaagtaa cgataagact gtggattgtc cccatcaagg cccacatact
    15361 catcaaggtt gacactggtt agatttgaaa aatcaaggtc actctcaaca atttccttgt
    15421 aaaattcaag tgggctactt cctgtcgcaa gtcctagagt ttgagctcca ttagccaatt
    15481 tttccttcaa aatctcaaaa gcaacttttc caccttgaac ttggttttca actttaataa
    15541 ctttcatctt ttcatcctcc atttctgtct atatttatta tatggtatag accaattttt
    15601 gtcaagtgaa aacgatttaa tttctaaaaa aagagcgtcc aaacttgaaa cgtgttataa
    15661 tggataggat tagaacttag aaagaatgaa cagatatatg aatacagctg attttgattt
    15721 ccacttgcca gaggaattga ttgcccaaac gccccttgaa aaacgtgatg cctccaaact
    15781 cctcatcgtc aaccgtgaga caggagaaat gcaagataaa cacttccact ctattattaa
    15841 tatgctggaa cctggtgatg cccttgtcat gaacgacacc cgagttctcc ctgcccgcct
    15901 ctatggtcaa aaagtggaga caggaggtca tgtggaactt ctcctcctta agaacactag
    15961 tggagacgag tgggaagttc tggctaaacc tgccaaacgc ctcaaggtcg gtactcgtat
    16021 cagctttggt gatggccgcc tcagcgctgt cgttacagaa gaattgaccc acgggggacg
    16081 cattgtccgc tttgaatacc aaggaatttt cctagaagtc ttggaaagtc tgggagaaat
    16141 gcctctgcca ccttatatcc acgaaaaatt agatgaccgt gaacgttatc aaaccgtcta
    16201 cgccaaggaa agcggctctg ctgcagcacc gactgctggt cttcacttca ccaaagaact
    16261 gctggcagaa atccaagcta agggtgttca tctagtctat ctgactctcc atgtcggact
    16321 cggaaccttt agacctgttt ctgtggataa tctggacgaa cacgaaatgc actcagagtt
    16381 ctatcaactt tctgaggaag ctgctgccac ccttcgctct gtcaaaaaaa atggtggtcg
    16441 tgtcatcgct gtcggaacca cttctatccg caccttggaa actattggtt ccaagtttga
    16501 tgggcaaatc caagcagatt ctggttggac caatatcttt atcaaacctg ggtatgagtg
    16561 gaaggtcgtg gatgccttct caaccaactt ccacctgcca aaatcaactc tggtcatgtt
    16621 ggtttctgcc tttgcaggcc gtgaattagt cttagatgcc taccaccatt ccatccaaga
    16681 acactaccgc ttcttcagtt ttggtgacgc catgtttatt tattgagaaa gaatttctct
    16741 aaatcttcta ataccaataa atcgctaaga tattatttca aagaacatct acaattgaaa
    16801 ctctagctag ctgtagaaga ggcctagtac attgaaatta aaatgcttcc ccctagcttc
    16861 gaaaatattg ccatagattg cgttgactct ccaaattgat tcatctatat tttatttcag
    16921 cttcctatac tttcttcgct gtttgtaaat caaaatgcaa gacacatgag tagcaccata
    16981 tttgttactc ttatctgtcc tctcaagaga ctattatgag ttatttcaga atcattcact
    17041 actttgaccc tgactctcct tagtctcaaa atcaaagact tatactcttc aaaaatctct
    17101 tcaaaccgcg tcaacgtcac cttggattat atatgtgact gactttgtca gttctatcta
    17161 caacctcaaa gcagtacttt gagcaacctg cgactagttt tctagtttgc tctttgattt
    17221 tcattgagta ttaaacaaaa agtgaacaaa tctgaattct aatgtacaga agactaggct
    17281 tgttcacttt tttatagtcg ctataagatg accttatcta tagcttttta tatataatta
    17341 tatattcaga catactatta tcaattttgt cgcagggagg aatctgttaa cgcacccatt
    17401 caccattatc attgactcta tagccatcta tacttgtatt gaccgctaac tcacccgatg
    17461 tatttacata ataccattta ccaccaactt ggaaccattg attgactttc atagaaccgt
    17521 tgctgttgag gtagtaccat gaaccattaa cttgtaccca acctgttgcc atggaaccat
    17581 cagtattata aaaataccac ataccatttt cttgtttcca gtctgttgtt ggagcaactg
    17641 ctttagctgg ttctactgct acatctgttc cttggttaga tgtaacagat acaggatacg
    17701 aaggaataga tgattgctca ggaacaacaa ctttttcagg ttctctcgtc cctctcctta
    17761 tacgtctttt taccatctct ttagtaattt gacgagaagt agtttcttca attgttccat
    17821 cacgttcatc tacagtatag attgtagtaa gagtaattta ccaatttctc ctacttcttc
    17881 tacttcttga cttttatcaa gagttgggcc atcgagatat tctgtttcga ttggaatttc
    17941 ttggacaaga acttggggct tggttccttt tttaacaact cttgtttgag agtctttttt
    18001 ttgacttaaa gtactctcag ttacttgtcc actctttcca tctacattat aagttatcgt
    18061 tgtaactgtt ttcccattct ttcctagagt aatctcttgc tcctgtcctg cagaaaggtc
    18121 attgtctgct tcatatttag tagcaaatgg aacaagaact tcttcaacct tgcttttagc
    18181 tggaactttg ataactgtat ccgtggcttc ttttctatca acagtaacct gttcggtaac
    18241 ataaccagtc tctggattaa catcgtaggt ccttgtcgta gttacatagc catcctctcc
    18301 atcaattgta acaggatttt cactacggtc ttttgtttca tctttttcat aacgaattcg
    18361 cgtacttgaa attttcttgg ttactacctt aggtttagtc gctactttta caataatatc
    18421 cccattgtca gcgtcatcat actctattcc ctcttcttta tctctagtat catctctgac
    18481 atattgaatc ccatcagcag catgaacaaa acttgtattc agattcctcc taaaaataaa
    18541 gttagcccga ttaccgcaga accaaaaatc tttccgagtt tacgtaatgc atagcgctta
    18601 ttagtattag attttgccat tacatcctac ttctagtata gcatcttttc tatcaaacat
    18661 taaacaatat actttatata taaaatagac ttagaatgat atattgatta ttgaactaac
    18721 actttaacta tatcgtaatc aatctcatat ataaagaatt
//
LOCUS       DAVLTT010000039        18563 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLTT010000039 DAVLTT010000000
VERSION     DAVLTT010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18563
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.039"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            829..1281
                     /locus_tag="VYN15_001447"
                     /pseudo
     CDS             829..1281
                     /locus_tag="VYN15_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
     gene            1300..2637
                     /locus_tag="VYN15_001448"
     CDS             1300..2637
                     /locus_tag="VYN15_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV1452753.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2716..3600
                     /locus_tag="VYN15_001449"
     CDS             2716..3600
                     /locus_tag="VYN15_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1452754.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHGVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3600..4433
                     /locus_tag="VYN15_001450"
     CDS             3600..4433
                     /locus_tag="VYN15_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1452755.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4451..6544
                     /gene="nanB"
                     /locus_tag="VYN15_001451"
     CDS             4451..6544
                     /gene="nanB"
                     /locus_tag="VYN15_001451"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV1452756.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINDHYYLKLKKNGDNDFRYTVRENGVVY
                     NETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6556..7659
                     /locus_tag="VYN15_001452"
     CDS             6556..7659
                     /locus_tag="VYN15_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1452757.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7833..8531
                     /locus_tag="VYN15_001453"
     CDS             7833..8531
                     /locus_tag="VYN15_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1452758.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8550..10067
                     /locus_tag="VYN15_001454"
     CDS             8550..10067
                     /locus_tag="VYN15_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1452759.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            10192..11520
                     /locus_tag="VYN15_001455"
     CDS             10192..11520
                     /locus_tag="VYN15_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1452760.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11772..12638
                     /locus_tag="VYN15_001456"
     CDS             11772..12638
                     /locus_tag="VYN15_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1452761.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12654..13493
                     /locus_tag="VYN15_001457"
     CDS             12654..13493
                     /locus_tag="VYN15_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1452762.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13766..14218
                     /locus_tag="VYN15_001458"
     CDS             13766..14218
                     /locus_tag="VYN15_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1452763.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14360..14668
                     /locus_tag="VYN15_001459"
     CDS             14360..14668
                     /locus_tag="VYN15_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452764.1"
                     /translation="MDGQGITVDEMAWIIRGIVNALIGRYIKLGTYAAKYGISMARSI
                     LSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAAAWDAHDKIPNNGRINF
                     "
     gene            14955..15599
                     /locus_tag="VYN15_001460"
     CDS             14955..15599
                     /locus_tag="VYN15_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1452765.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEIKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15768..16685
                     /locus_tag="VYN15_001461"
     CDS             15768..16685
                     /locus_tag="VYN15_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV1452766.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEDLNIGSVR
                     SPLTPVTEEDRPVVEVAAALIRETKERFL"
     gene            16703..17587
                     /locus_tag="VYN15_001462"
     CDS             16703..17587
                     /locus_tag="VYN15_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1452767.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17603..18454)
                     /locus_tag="VYN15_001463"
     CDS             complement(17603..18454)
                     /locus_tag="VYN15_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1452768.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
BASE COUNT         5857 a         3133 c         3859 g         5714 t
ORIGIN      
        1 gttagaaatt agtttgaatt ttccaatcaa tttgttcgat ttttacatca ttgcattata
       61 tcatgtgact attaaccttg ttttctccta aaattgattt tcttcttttc ttatcttgtc
      121 cactcgaaac aagtattgta agaatttgat tatttttgaa agtactttta atatatttga
      181 gatagttaaa aaagatttga aactaaattc caaattagaa aaagacttga aatgctaaaa
      241 aaaaaaagta tactctaatt gaaaacggta acaaaactaa tttagagaat gaaatataga
      301 gtatttctct cttaaaagtt tttggtgaaa cgagatgtag aaaggagatt tagccaaaga
      361 gtctattagt gctagaataa tagattagaa ttattttaga aaaacgaagt gagcagctta
      421 taaattcaag tccccaaata gattcatact agtatctttt gcaaaaaata aagggcgact
      481 tccttcatga atatcaattt catctataag gaaggtagct aattgaacta acttatttat
      541 tctgtttgtc gctagaaaaa tcagacctcc ttgtgaagat tgaggagata cttaatgaaa
      601 atcaaagaag aaactagcaa gctagtagca gattgcccaa aacaccgctt tgaggttgta
      661 gataagactg acctatataa tccaaggtga agcgactgtg gtttgaagag attttcaaag
      721 agtataggct agagagtagt gtttttatgt ccttctagta gaaaatgcta gacagaagaa
      781 tggggaactt ggataggaaa aatagattga gaaaggaggt tagaagagat gattattaca
      841 aaaattagcc gtttaggaac ttatgtggga gtaaatccac attttgcaac attaatagat
      901 tttctagaaa aaacaggact agaaaattta acagaaggtt cgattgctat cgatggtaat
      961 cgattgtttg ggaattgctt tacttatcta gcagatggtc aagcaggggc tttctttgaa
     1021 acacaccaaa aatatttgga tattcattta gttttggaaa acgaagaagc catggctgtt
     1081 acatcgccgg aaaatgtaag cgttacccaa taatatgatg aagagaaaga tattgaatta
     1141 tacacaggga aagtggaaca gttggttcat ttgagagctg gtgaatgcct catcactttt
     1201 ccagaagatt tacatcaacc caaggttcgt ataaatgatg aacctgtgaa aaaagttgtc
     1261 tttaaagttg cgatttctta atgtagaaag agaagaacga tgaaaaaaat gagaaagttt
     1321 ttatgtctag ctggaattgc gctagcggct gttgccttgg tagcttgttc aggaaaaaaa
     1381 gaagctacaa ctagtactga accaccaaca gaattatctg gtgaaattac aatgtggcac
     1441 tcctttactc aaggaccccg tttagaaagt attcaaaaat cagcagatgc tttcatgcaa
     1501 aagcatccaa aaacgaaaat caagattgaa acattttctt ggaatgactt ctatactaaa
     1561 tggactacag gtttagcaaa tggaaatgtg ccagatatca gtacagctct tcctaaccaa
     1621 gtaatggaaa tggtcaactc agatgctttg gttccgctaa atgattctat caagcgtatt
     1681 ggacaagata aatttaacga aactgcctta aatgaagcaa aaatcggaga tgattactac
     1741 tctgttcctc tttattcaca tgcacaagtc atgtgggtta gaacagattt gttaaaagaa
     1801 cataatattg aggttcctaa aacttgggat caactctatg aagcttctaa aaaattgaaa
     1861 gaagctggag tttatggctt gtctgttccg tttggaacaa atgacttaat ggcaacacgt
     1921 ttcttgaact tctacgtacg tagtggtgga ggaagcctct taacaaaaga tcttaaagca
     1981 gacttgacaa gccaacttgc tcaagatggt attaaatact gggttaaatt gtataaagaa
     2041 atctcacctc aagattcttt gaattttaat gtccttcaac aagctacctt gttctatcaa
     2101 ggaaaaacag catttgactt taactctggc ttccatatcg gaggaattaa tgccaacagt
     2161 cctcaattga ttgattcgat tgatgcttat cctattccaa aaatcaaaga gtctgataaa
     2221 gaccaaggaa ttgaaacctc aaacattcca atggttgttt ggaaaaattc aaaacatcca
     2281 gaagttgcta aagcattctt agaagcactt tataatgaag aagactacgt taaattcctt
     2341 gattcaactc cagtaggtat gttgccaact attaagggga ttagcgattc tgcagcctat
     2401 aaagaaaatg aaactcgtaa gaagtttaaa catgctgaag aagtaattac tgaagctgtt
     2461 aaaaaaggta ctgctattgg ttatgaaaat ggaccaagtg tacaagctgg tatgttgact
     2521 aaccaacaca ttattgaaca aatgttccaa gatatcatta caaatggaac agatcctatg
     2581 aaagcagcaa aagaagcaga aaaacaatta aacgatttat ttgaggctgt tcagtagatg
     2641 taaaagacta gaaaataggt gggctagtga tctgaaaagc tctagcccaa ttttgtaaaa
     2701 gaagggagaa ggagaatggt taaagaacgt aatttaactc gctggatatt tgttttgcca
     2761 gctatgatta tcgtaggatt actctttgtt tatccgtttt tctcgagtat tttttatagc
     2821 tttaccaata agcatttgat tatgcctaat tataaatttg ttggtttggc taactataaa
     2881 gctgtgctat cagatcccaa cttctttaat gcgttcttta attcaattaa gtggaccgtt
     2941 ttctcattag ttggtcaagt tttagtaggg tttgtattgg ctttagctct tcacggagta
     3001 cgccacttca agaaattata taggacctta ttgattgttc cttgggcatt tcctaccatc
     3061 gttattgcct tctcttggca gtggattcta aacggggttt atggctactt acctaatcta
     3121 atcgtaaaat taggtttaat ggaacataca cctgcatttt tgacagatag tacatgggca
     3181 ttcctatgtt tggtgtttat caacatttgg tttggagcac caatgattat ggttaatgtg
     3241 ctttcagctt tgcaaacagt accagaagaa caatttgagg ctgctaagat agatggtgct
     3301 tcaagttggc aggtgttcaa gtttatcgtc tttccacata ttaaagtggt tgtaggactt
     3361 ctagttgttt tgagaactgt atggatcttt aataactttg acattatcta cctcattact
     3421 ggtggtggac cagccaatgc tacaacgacg cttccaattt ttgcttacaa cctgggctgg
     3481 ggaactaaat tgttgggtcg tgcttcagca gttacagtac tgctctttat cttcttggtg
     3541 gcgatttgct ttatctactt tgctatcatc agtaagtggg aaaaggaggg tagaaaataa
     3601 tgaagaagaa atccagtatt tatttagata ttctctcaca tgtactttta gttggtgcga
     3661 ccatcgttgc agttttccca ttggtatgga ttatcatatc ttctgtcaaa gggaaagggg
     3721 aattaactca gtatccaaca cgattttggc ctgaacagtt tacattagat tatttcactc
     3781 atgttatcaa cgatttgcac ttcattgata acattcgaaa cagtttaatc attgccttgg
     3841 ctacaaccct tattgcgatt attatttctg ctatggcagc ctatggtatt gttcgattct
     3901 ttcctaaatt gggagcaatc atgtcgagac tactcgtcat tacctacatt ttcccaccaa
     3961 ttttgttagc aattccctat tcaattgcca ttgctaaagt tgggttaaca aatagtttat
     4021 ttggcttgat gatggtttat ctatctttta gtgttccata tgcagtttgg ctcttagttg
     4081 gatttttcca aacagttcca attggaattg aagaagcggc tagaattgat ggtgcaaata
     4141 aatttgttac gttttataaa gttgtgctac cgattgtagc accaggtatt gtagcaacag
     4201 ctatttatac atttatcaat gcttggaatg aattcctgta tgccttgatt ttgattaaca
     4261 atacaggaaa gatgacagta gcagtagccc ttcgttcact taatggttca gaaatactag
     4321 actggggaga tatgatggca gcgtctgtta ttgtagttct tccatcaatt attttcttct
     4381 ctatcatcca aaataagatt gcaagtggat tatcagaagg atctgtgaag tagacgaaag
     4441 aaggaaaaaa atgaataaaa gaggtcttta ttcaaaacta ggaatttccg ttgtaggcat
     4501 tagtctttta atgggagtcc ccactttgat tcatgcgaat gaattaaact atggtcaact
     4561 gtccatatct cctatttttc aaggaggttc atatcaactg aacaataaga gtatagatat
     4621 cagctctttg ttattagata aattgtctgg agagagtcag acagtagtaa tgaaatttaa
     4681 agcagataaa ccaaactctc ttcaagcttt gtttggccta tctaatagta aagcaggctt
     4741 taaaaataat tacttttcaa ttttcatgag agattctggt gagataggtg tagaaataag
     4801 agacgcccaa aagggaataa attatttatt ttccagacca gcttcattat ggggaaaaca
     4861 taaaggacag gcagttgaaa atacactagt atttgtatct gattctaaag ataaaacata
     4921 cacaatgtat gttaatggaa tagaagtgtt ctctgaaaca gttgatacat ttttgccaat
     4981 ttcaaatata aatggtatag ataaggcaac actaggagct gttaatcgtg aaggtaagga
     5041 acattacctc gcaaaaggaa gtattgatga aatcagtcta tttaacaaag caattagtga
     5101 tcaggaagtt tcaactattc ccttgtcaaa tccatttcag ttaattttcc aatcaggaga
     5161 ttctactcaa gctaactatt ttagaatacc gacactatat acattaagta gtggaagagt
     5221 tctatcaagt attgatgcac gttatggtgg gactcatgat tctaaaagta agattaatat
     5281 tgccacttct tatagtgatg ataatgggaa aacgtggagt gagccaattt ttgctatgaa
     5341 gtttaatgac tatgaggagc agttagttta ctggccacga gataataaat taaagaatag
     5401 tcaaattagt ggaagtgctt cattcataga ttcatccatt gttgaagata aaaaatctgg
     5461 gaaaacgata ttactagctg atgttatgcc tgcgggtatt ggaaataata atgcaaataa
     5521 agccgactca ggttttaaag aaataaatga tcattattat ttaaaactaa agaagaatgg
     5581 agataacgat ttccgttata cagttagaga aaatggtgtc gtttataatg aaacaactaa
     5641 taaacctaca aattatacta taaatgataa gtatgaagtt ttggagggag gaaagtcttt
     5701 aacagtcgaa caatattcgg ttgattttga tagtggctct ttaagagaaa ggcataatgg
     5761 aaaacaggtt cctatgaatg ttttctacaa agattcgtta tttaaagtga ctcctactaa
     5821 ttatatagca atgacaacta gtcagaatag aggagagagt tgggaacaat ttaagttgtt
     5881 gcctccgttc ttaggagaaa aacataatgg aacttactta tgtcccggac aaggtttagc
     5941 attaaaatca agtaacagat tgatttttgc aacatatact agtggagaac taacctatct
     6001 catttctgat gatagtggtc aaacatggaa gaaatcctca gcttcaattc cgtttaaaaa
     6061 tgcaacagca gaagcacaaa tggttgaact gagagatggt gtgattagaa cattctttag
     6121 aaccactaca ggtaagatag cttatatgac tagtagagat tctggagaaa catggtcgaa
     6181 agtttcgtat attgatggaa tccaacaaac ttcatatggc acacaagtat ctgcaattaa
     6241 atactctcaa ttaattgatg gaaaagaagc agtcattttg agtacaccaa attctagaag
     6301 tggccgtaag ggaggtcaat tagttgtcgg tttagtcaat aaagaagatg atagtattga
     6361 ttggaaatac cactatgata ttgatttgcc ttcgtatggt tatgcctatt ctgcgattac
     6421 agaattgcca aatcatcaca taggtgtact gtttgaaaaa tatgattcgt ggtcgagaaa
     6481 tgaattgcat ttaagcaatg tagttcagta tatagatttg gaaattaatg atttaacaaa
     6541 ataaaggaga aaaacatggt taaatacggt gttgttggag cagggtattt tggagctgaa
     6601 ttggctcgct acatgcaaaa gaatgatgga gcagagatta ctcttctcta tgatccagat
     6661 aatgcagagg cgattgcaga agaattgggg gcaaaagtag caagttcctt agatgagttg
     6721 gtttctagcg atgaagtaga ttgtgttatc gtcgcaactc caaataatct tcataaggaa
     6781 ccggttatta aggctgcaca gcatggtaaa aatgttttct gtgaaaaacc aattgcgctt
     6841 tcttatcaag attgtcgcga gatggtagat gcgtgtaaag aaaacaatgt aacctttatg
     6901 gcaggacata ttatgaattt ctttaatggt gttcatcatg caaaagaact cattaatcaa
     6961 ggagttatcg gagacgttct atattgtcat acagctcgta atggttggga agaacaacaa
     7021 ccgtcagtat catggaaaaa aattcgtgaa aaatcaggtg gtcacttgta tcaccacatc
     7081 catgaattgg attgcgttca attccttatg gggggcatgc ctgaaactgt aaccatgaca
     7141 ggtggaaatg tggcccatga aggtgaacat ttcggtgatg aagatgatat gatttttgtc
     7201 aatatggaat tttctaataa gcgttttgcc ttgttagaat ggggttcagc ttatcgttgg
     7261 ggtgaacatt atgtcttaat ccaaggaagc aaaggtgcca tccgcttaga cttattcaac
     7321 tgtaaaggaa ctcttaagct agatgggcaa gaaagctatt tcttgattca cgaatcgcaa
     7381 gaagaagatg atgatcggac tcgtatctat catagtacag agatggatgg agcaattgct
     7441 tatggtaaac caggtaaacg tactccatta tggctatcat ctgtcattga taaagaaatg
     7501 cgctatctgc atgagattat ggaaggagct ccagtatcag aagaatttgc aaaacttttg
     7561 acaggtgaag ctgccctaga agcaattgct actgcagatg cttgtaccca gtctatgttt
     7621 gaagatcgca aagtaaaatt gtcagaaatt gtaaaataaa ttttggtatt ctcctattta
     7681 taggtcgact tgctcctctg aaagtacttt tagaggagct gtttgacttt gctagttttt
     7741 gaaactgaaa tctattatac tacaaactat tgaaagcgtt ttaattttaa ggtataataa
     7801 tctcatagaa ataaagaaaa ggaggaaaga ggatgccaca gattagcaaa gaagccttga
     7861 ttgagcaaat caaagatgga atcatcgttt cttgtcaggc tcttcctcat gaaccgcttt
     7921 atacagaagc gggaggggtg attcccttgc tggtcaaagc ggctgagcaa ggtggagcag
     7981 tcggtatccg agcaaacagt gttcgcgata tcaaggaaat taaggaagtc actaaacttc
     8041 caatcattgg gattatcaaa cgtgattatc cacctcagga acccttcatc acggctacta
     8101 tgaaagaagt tgatgaattg gcagaactgg acatcgaggt gattgctctg gattgtacca
     8161 agcgtgaacg ctacgatggt ttggaaattc aagagttcat tcgtcaggtt aaggagaaat
     8221 atcctaatca gcttttgatg gctgatacta gtatcttcga agaagggcta gcagctgtag
     8281 aagcaggaat tgactttgtc ggaacaacct tatcaggcta cacatcctac agtccaaaag
     8341 tagacggtcc agattttgaa ttgattaaga aactctgtga tgccggtgta gatgtcattg
     8401 cagaaggaaa aattcataca ccagaacaag ccaaacaaat ccttgaatat ggagtgcgag
     8461 gcatcgttgt tggtggcgcc attactagac caaaagagat tacagaacgc ttcgttgcta
     8521 gtcttaaata agatgtgagg gggagtttta tgtttaaagt tttacaaaaa gttggaaaag
     8581 cttttatgtt acctatagct atacttcctg cagcaggtct acttttgggg attggtggtg
     8641 cactttcaaa cccaaccacg atagcaactt atccaatact agacaatagt atttttcaat
     8701 caatattcca agtaatgagc tctgcaggag aggttgtatt cagtaatttg tcactacttc
     8761 tctgtgtggg attatgtatt ggcttagcga aacgagataa aggaaccgct gcgttagcag
     8821 gagtaactgg ttacttagtt atgactgcaa cgatcaaagc tttagtaaaa ctttttatgg
     8881 cagaaggatc tgcaattgat actggagtta ttggagcatt agttgtcgga atagttgccg
     8941 tatatttgca caaccgatat aacaatattc aattaccttc cgctttagga ttctttggag
     9001 gttcacgctt cgttcctatt gttacatcgt tctcttctat cttgattggc tttgtcttct
     9061 ttgttatttg gccacctttc caacaacttc ttgtttctac aggtggatat atttctcagg
     9121 cgggtccaat tggaactttt ctatatggat ttttaatgag actttctgga gcagtaggct
     9181 tacatcatat aatttaccct atgttttggt atactgaact tggtggtgtt gaaactgttg
     9241 caggacaaac agtggttgga gctcaaaaaa tattttttgc tcaattagcc gatttggccc
     9301 attctggatt atttacagaa ggaacaaggt tttttgcagg tcgtttctca acaatgatgt
     9361 tcggtttacc ggctgcctgt ttagcgatgt accatagtgt tcctaaaaat cgtcgtaaaa
     9421 aatacgcggg tttgtttttt ggagttgctt taacatcttt tattaccggt attacagaac
     9481 caattgaatt tatgtttcta ttcgtcagtc cggttctata tgttgttcac gcattccttg
     9541 atggtgttag cttctttatt gcagacgtct taaatatttc aataggaaac acattttcag
     9601 gaggtgtaat cgatttcact ttatttggaa ttttgcaggg gaacgctaag acgaattggg
     9661 ttcttcagat tccatttgga cttatttgga gtgttttgta ttatattatt tttagatggt
     9721 tcattactca attcaacgtt ctaacgccag ggcgaggaga agaagtagat tctaaagaaa
     9781 tttctgaatc cgcagattca acttcaaata ctgcagatta tttaaaacag gatagcctac
     9841 aaattatcag agccttgggt ggatcaaata atatagaaga tgtagatgct tgtgtgacac
     9901 gtttacgtgt agctgtaaaa gaagttaatc aagttgataa agcactttta aaacaaattg
     9961 gtgcagttga tgtcttagaa gtgaagggtg gcattcaagc aatctatgga gcaaaagcaa
    10021 tcttatataa aaatagtatt aatgaaattt taggtgtaga tgattaagta cttactgact
    10081 taataaaaaa cagaggagag tgatggatga gtaggatgaa atgaaatcgc atacaagaaa
    10141 taaagaactc attatccaag ttggatacgc ttattacata ggagaataca aatgaaattt
    10201 agaaaattag cttgtacagt acttgcgggt gctgcggttc ttggtcttgc tgcttgtggc
    10261 aattctggcg gaagtaaaga tgctgccaaa tcaggtggtg acggtgccaa aacagaaatc
    10321 acttggtggg cattcccagt atttacccaa gaaaaaactg gtgacggtgt tggaacttat
    10381 gaaaaatcaa tcatcgaagc gtttgaaaaa gcaaacccag atataaaagt gaaattggaa
    10441 accatcgact tcaagtcagg tcctgaaaaa atcacaacag ccatcgaagc aggaacagct
    10501 ccagacgtac tctttgatgc accaggacgt atcatccaat acggtaaaaa cggtaaattg
    10561 gctgagttga atgacctctt cacagatgaa tttgttaaag atgtcaacaa tgaaaacatc
    10621 gtacaagcaa gtaaagctgg agacaaggct tatatgtatc cgattagttc tgccccattc
    10681 tacatggcaa tgaacaagaa aatgttagaa gatgctggag tagcaaacct tgtaaaagaa
    10741 ggttggacaa ctgatgattt tgaaaaagta ttgaaagcac ttaaagacaa gggttacaca
    10801 ccaggttcat tgttcagttc tggtcaaggg ggagaccaag gaacacgtgc ctttatctct
    10861 aacctttata gcggttctgt aacagatgaa aaagttagca aatatacaac tgatgatcct
    10921 aaattcgtca aaggtcttga aaaagcaact agctggatta aagacaattt gatcaataat
    10981 ggttcacaat ttgacggtgg ggcagatatc caaaactttg ccaacggtca aacatcttac
    11041 acaatccttt gggcaccagc tcaaaatggt atccaagcta aacttttaga agcaagtaag
    11101 gtagaagtgg tagaagtacc attcccatca gacgaaggta agccagctct tgaatacctt
    11161 gtaaacgggt ttgcagtatt caacaataaa gacgacaaga aagtcgctgc atctaagaaa
    11221 ttcatccagt ttatcgcaga tgacaaggag tggggaccta aagacgtagt tcgtacaggt
    11281 gctttcccag tccgtacttc atttggaaaa ctttatgaag acaaacgcat ggaaacaatc
    11341 agcggctgga ctcaatacta ctcaccatac tacaacacta ttgatggatt tgctgaaatg
    11401 agaacacttt ggttcccaat gttgcaatct gtatcaaatg gtgacgaaaa accagcagat
    11461 gctttgaaag ccttcactga aaaagcgaac gaaacaatca aaaaagctat gaaacaatag
    11521 tccttagtta ttctataaaa agtagttttt taaagaacct aagagtgtat accccctttt
    11581 ccctctacac agatagtgta agaaaagggg gcttttgttt aaaatgtaag aaactgtcac
    11641 gaaattaaaa tgaagttctt acataagcga atcataaaaa atttcatttt gattttaaaa
    11701 cagttcaaga aagtcaaaaa attattctat ttgaaagaga ggtgccgact gtgaaagtca
    11761 ataaaatccg tatgcgggaa acagtgattt cctacgcttt cctagcacca gtattattct
    11821 tctttgtcat ctttgtgttg gctccgatgg tgatgggctt cattacaagt ttctttaact
    11881 actcaatgac taaatttgag tttgtaggct tggataacta tatccgtatg tttaaagatc
    11941 ctgtctttac aaaatctctg attaacacag ttattttggt tattggatct gtaccagttg
    12001 ttgttctatt ctcactcttt gtagcatctc agacctatca tcaaaatgtc attgccagat
    12061 ccttctaccg tttcgtcttc ttccttcctg ttgtaacggg tagtgttgcc gtgacagttg
    12121 tttggaaatg gatttatgac ccactatcag gaattctaaa ctttgtcctt aagtcaagcc
    12181 acatcatcag ccaaaacatt tcttggttgg gagataaaaa ctgggcattg atggcgatta
    12241 tgattattct cttgaccact tcagttggtc agcccatcat cctttatatc gctgccatgg
    12301 ggaatatcga caattcactg gttgaagcgg cgcgtgttga tggtgcaact gagtttcaag
    12361 ttttttggaa gattaaatgg ccaagccttc ttccaacaac tctttatatt gcaatcatca
    12421 caacaattaa ctcattccag tgtttcgcct tgattcagct tttgacatct ggtggtccaa
    12481 actactcaac aagtaccttg atgtactacc tttacgaaaa agccttccaa ttgacagaat
    12541 acggctatgc caacacaatt ggtgtcttct tggcagtcat gattgctatc gtaagctttg
    12601 ttcaatttaa agtacttgga aacgacgtag aatactaaag aaaggagaca gctatgcaat
    12661 ctacagaaaa aaaaccatta acagccttta ctgttatttc aacaatcatt ttgctcttgt
    12721 tgactgtgct gttcatcttt ccattctact ggattttgac aggggcattc aaatcacaac
    12781 ctgatacaat tgttattcct cctcagtggt tccctaaaat gccaaccatg gaaaacttcc
    12841 aacaactcat ggtgcagaac cctgccttgc aatggatgtg gaactcagta tttatctcat
    12901 tggtaaccat gttcttagtt tgtgcaacct catctctagc aggttatgta ttggctaaaa
    12961 aacgtttcta tggtcaacgc attctatttg ctatctttat cgctgctatg gcgcttccaa
    13021 aacaagttgt ccttgtacca ttggtacgta tcgtcaactt catgggaatc cacgatactc
    13081 tctgggcagt tatcttgcct ttgattggat ggccattcgg tgtcttcctc atgaaacagt
    13141 tcagtgaaaa tatccctaca gagttgcttg aatcagctaa aatcgacggt tgtggtgaga
    13201 ttcgtacctt ctggagtgta gccttcccga ttgtgaaacc agggtttgca gcccttgcaa
    13261 tctttacctt catcaatact tggaatgact acttcatgca attggtaatg ttgacttcac
    13321 gtaacaattt gaccatctca cttggggttg cgaccatgca ggctgaaatg gcaaccaact
    13381 atggtttgat tatggcagga gctgcccttg ctgctgttcc aatcgtcaca gtcttcctag
    13441 tcttccaaaa atccttcaca cagggtatta ctatgggagc ggtcaaagga taatactctg
    13501 cgaaaatcga atgcaaacta cgtcagcttc accttgccat acttaagtat tgcctgcggt
    13561 tagcttccta gtttgttctt caattttcat tgagtatagg aaaatcaatc tatcaagata
    13621 cagaagtata ttttatagat ttagagaata tagaggttat aagtgtctac aaaatggagg
    13681 gtatgcagtt actttatgaa gttttgtcag acacttatca acttaagaat ggttttagtt
    13741 aactatcaga aacgaaggaa agagtatgat ttttgacgat ttgaaaaaca tcacctttta
    13801 caaagggatt catcccaatt tagacaaggc tatcgactac ctctaccaac atcgtaaaga
    13861 ttcattcgaa ttaggaaagt atgagattga tggagataaa gtctttctag ttgttcagga
    13921 aaatgtcctc aatcaagttg agaataatca atttgaacac cataagaact atgcagattt
    13981 gcatttgctg atagaagggc atgaatattc gagctacggt tcacgtatca aagacgaggc
    14041 agtagcattc gacgaagcga gtgacattgg ctttgttcat tgtcatgaac actacccgct
    14101 cttgttgggt tatcacaatt ttgcgatttt cttcccaggt gagccacatc agccaaatgg
    14161 ttatgcaggc atggaagaaa aggttcgaaa atatctcttt aaaatcttga ttgattaaaa
    14221 ataggatgaa ttgttttttt gtaaagcttt gataatactc taccatgaaa ttgatctttg
    14281 tgaggtagag aaatgagaat aaaatattta aaaattggta tcttcttgtc agtctgtgta
    14341 tgctacaaga gctagtttct tggatggaca gggaattaca gttgatgaga tggcttggat
    14401 aattaggggc attgtgaatg cattgattgg tagatacata aaattaggta cttatgcagc
    14461 taagtatggt attagtatgg cgcgctcgat cttaagtagg gcagctgcaa ctgcggcagc
    14521 aagagtagga ttattgacta agatttttgg atggatttta cgaatagctg tgctcgcagc
    14581 tgatgtatat ggtaattttg ccaacaatat tgctgcagct tgggatgcac atgataaaat
    14641 ccctaacaat ggtcgtataa acttttaaaa tgcgagaatg aaagcacttt gtattttttt
    14701 attgtatatg ttagcttgga cagtgcttgc aatgataatc cgtggagggc tagatggatt
    14761 tgatgaacac acttggcgta atattttagc tagtgcgttg tcctcgctat acatacatta
    14821 tatatccata gatagaaaaa gaaaaaagtc caaaagaaaa aagaaaaaat agatttgttc
    14881 atggtaggga cttatgaaag ctttactaac aaaaaagaaa acagtttaca aagaaaaatg
    14941 atggaggagt aaacatggca caaaaaggag taagccttat caaggcagca tttgatacag
    15001 ataactttct tatgcgtttt agtgagaaag tcttggacat cgtgacagcc aatcttcttt
    15061 ttgtcgtctc ttgtttgccc atcgtgacga ttggagtggc taaaatcagc ctctacgaga
    15121 ccatgtttga gattaagaag agcagacggg tgcctgtttt taaaatctat ctaagatctt
    15181 tcaagcaaaa tctgaaacta ggtcttcagt taggtctgct tgagttgggc attgtttcat
    15241 taagcctcct agatctttat ctcttttggg gtcaaacagc tctgcccttt caattgctga
    15301 aagctatttg tctaggcatt ctgattttcc ttacgattgt gatgttggct agctatccaa
    15361 tcgcggcacg ttatgattta acttggaaag aagtgttaca aaaagggctt atcttggcaa
    15421 gttttaactt tccttggttc ttcctcatgt tagccattct tgtcctcatt gtgatggttc
    15481 tttatctgtc cgccttcagt ctactcttag gtggctcagt cttcctactt tttgggtttg
    15541 gactattggt ctttatccag actggattga tggagaaaat tttcgcaaaa taccaatagg
    15601 agccttattt ctgaaactac tttcaaaggc tccaaacgct attctataag cgagaaacta
    15661 aaatctaagt gtctataaga tattgaaagc cttttcggta aagtgtatac taaagaagta
    15721 aagaaaaatc tgctttagca gaaaataaaa ataataggag aaaatctatg tcagatttga
    15781 aaaaatacga aggtgtcatt ccagccttct acgcatgtta tgatgatcaa ggagaagtaa
    15841 gcccagaacg tacgcgtgcc ttggttcaat acttcattga taaaggtgtt caaggtcttt
    15901 atgtcaatgg ttcttctggt gaatgtatct accaaagcgt tgaagatcgc aagttgattt
    15961 tggaagaagt catggcggta gccaaaggta aattgaccat cattgctcat gttgcctgca
    16021 acaatactaa agacagtatg gaacttgctc gccatgctga aagcttggga gtagatgcta
    16081 ttgcaacgat tccaccaatt tatttccgct tgccagaata ctcagttgcc aaatactgga
    16141 acgatatcag ttctgcagct ccaaacacag actacgtgat ttacaacatt cctcaattgg
    16201 caggggttgc tttgactcca agcctttaca cagaaatgtt gaaaaatcct cgtgttatcg
    16261 gtgtgaagaa ctcttctatg ccagttcaag atatccaaac ctttgtcagc cttggcgggg
    16321 aagaccatat tgtctttaac ggtccagatg aacagttcct aggtggccgc ctcatgggtg
    16381 ctagggctgg tatcggtggt acttatggtg ctatgccaga actcttcttg aaactcaatc
    16441 agttgattgc ggataaggac ctagaaacag cgcgtgaatt gcagtatgct atcaacgcaa
    16501 tcattggtaa actcacttct gctcatggaa atatgtacgg tgtcatcaaa gaagttttga
    16561 agatcaatga agacttgaat attggttctg ttcgttcacc attgacacca gtgactgaag
    16621 aagatcgtcc agttgtagaa gtagctgcag ccttgattcg tgaaaccaag gagcgcttcc
    16681 tctaatctaa aaggaggtat ttatgacata ctacgttgca attgatatcg gtggaaccaa
    16741 catcaagtat ggtttggttg atcaagaggg gcaacttctt gaatcgcatg aaatgccaac
    16801 tgaggcgcat aagggtggac ctcatatctt acaaaagacc aaagatatcg tagctagtta
    16861 tttagaaaaa ggcccagtag caggtgttgc catatcttct gctgggatgg tggatccgga
    16921 taagggtgag attttctatg ctgggccgca aatccctaac tacgcaggca cccagttcaa
    16981 aaaggaaatc gaagaaagct ttactattcc ttgtgagatt gaaaatgatg tcaactgtgc
    17041 aggtcttgct gaggcagtat ctggttcagg caagggagca agtgtgacac tttgcttgac
    17101 cattggaaca ggtatcggtg gttgcttgat tatggatagg aaagtcttcc atggttttag
    17161 caattcagcc tgtgaagtcg ggtatatgca tatgcaggat ggagcttttc aggatctcgc
    17221 ttctacaaca gctttagtga aatatgtagc tgaagcccat ggagaagatg ttgatcagtg
    17281 gaatggccga cgtatcttta aggaagctac tgaaggaaac aaaatctgca tggaaggcat
    17341 tgaccgtatg gttgactatc taggaaaagg tctggcaaat atttgctacg ttgccaatcc
    17401 agaagtggtt attcttggtg gtggtatcat ggggcaagag gctatcctca aacctaagat
    17461 ccgcacagcc ttgaaagagg ctttggtacc aagtttagca gaaaaaacac gattagaatt
    17521 tgcccatcac caaaatacag cagggatgtt gggtgcatat tatcatttta agacaaaaca
    17581 atcctagttt ggctcagcca aactaggatt ttcttacacg tttttgtcta cgatagccgt
    17641 tgagtttttt attttcccag tagctattaa agattttttc cttgctttcg cgattgattt
    17701 ccaaaaagta ggcataaatc aaatcgataa agaagagcat aggaagttga gcggatattc
    17761 gttggatata ggagggttgg ctgtgggtgg ctacaagaac agtctctgta taggtctggc
    17821 tatctttatt gggaacactt gtaaagagta cagtctttgc ccccatctcc ttagcatcta
    17881 atagactatc taaaatagaa ggagttgagc ctgaaagtga gaagcccagt actagacaat
    17941 tttcatccat gatgctggtt gtccaggcaa agccgtcttg gtctgtcaaa gcttcgcaga
    18001 ccacacctag tcgcataaaa cgtaatttca tttcacgggc gacgaggcca gaactccctg
    18061 ttccaaagaa gtagatacgc tcagcatctt cgattagctg ggcaattcgt tctagttgga
    18121 tttcgtcaat caagtcttgt gtttgttccc tcatattgct ataacttctg aggactcgtt
    18181 tggtcagtgg actgtgcttg gagacttggt tggcttgatt ttctgcctga tgttggtatt
    18241 ggaaaataaa ttctcggtag ccagtaaagc cacacttttt agcaaagcgg gtcaaagcag
    18301 cttgagaaat atgtaatttt tgggtgactt gttgagaaga taaatcatct gtaatcgttt
    18361 cagcttgcaa aaaatagcga gcgatttctt gttctaggtc tgtcatttct tcaaaatgtg
    18421 aatcaatgat agttgcgata tctggtttgt ccatagggaa agctccttta catgagtcat
    18481 actggaagac tagatcagag aatagtcaca cttcattata acacataata taaggataga
    18541 taaataaaaa cgcatctctg ttt
//
LOCUS       DAVLTT010000040        18478 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLTT010000040 DAVLTT010000000
VERSION     DAVLTT010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.040"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            408..3683
                     /gene="rexB"
                     /locus_tag="VYN15_001464"
     CDS             408..3683
                     /gene="rexB"
                     /locus_tag="VYN15_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV1452769.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3680..7330
                     /gene="addA"
                     /locus_tag="VYN15_001465"
     CDS             3680..7330
                     /gene="addA"
                     /locus_tag="VYN15_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV1452770.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQKGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7500..8678
                     /locus_tag="VYN15_001466"
     CDS             7500..8678
                     /locus_tag="VYN15_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452771.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSFIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSNFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            8887..14778
                     /gene="iga"
                     /locus_tag="VYN15_001467"
     CDS             8887..14778
                     /gene="iga"
                     /locus_tag="VYN15_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HEV1452772.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     NPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELY
                     LEDQFSKTKQNLGDSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     QHGATDLFSTLEHYRKVFLPNTSNNDWFKSQTKAYIVEEKSTIEEVKTKQGLAGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALN
                     DFVEENARETAKRQRDHYDYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEA
                     KFDSSNPAMKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVL
                     DPTERFQNAADLQNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDP
                     ADGNEVYATNVVKELTEAEARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAP
                     IYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGSRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            14830..15006
                     /locus_tag="VYN15_001468"
     CDS             14830..15006
                     /locus_tag="VYN15_001468"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1452773.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            15225..16076
                     /gene="ylqF"
                     /locus_tag="VYN15_001469"
     CDS             15225..16076
                     /gene="ylqF"
                     /locus_tag="VYN15_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV1452774.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQVIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            16063..16842
                     /locus_tag="VYN15_001470"
     CDS             16063..16842
                     /locus_tag="VYN15_001470"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV1452775.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKD
                     LNDSKKIPKKKHLEIFQAVQDQSLSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            16858..18408
                     /locus_tag="VYN15_001471"
     CDS             16858..18408
                     /locus_tag="VYN15_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV1452776.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIIGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         5985 a         3660 c         3861 g         4972 t
ORIGIN      
        1 cacgatgtac tattatagtt tcaatttact atagttcaat cattctatca agaatattga
       61 atatataaag gcacgtaata ttaaaacttc ttctgatatc gaattagagt ccgatgttga
      121 tggcgataaa tcagacaatc tacccgtcga cattaagata ctgggacaac acattgaagt
      181 gtattccgta cctaagaaac aatcataaaa ctcaaagtct tgttaccgag gcttttttat
      241 tatgtgattt tcagtagcca gacttattct atctaataca agtaaagcta agtatttaag
      301 atttagcaga tgatgaagaa aagaaaggat ggcctaaata ttttaacaga tttacgaggc
      361 taatcatggt ataatatagg gtgatgaaaa attccaacga ggctgagatg aaattacttt
      421 atactgatat tcgaacttct ttgacagaaa ttctaacaag agaggcagaa gagctagttg
      481 cagctggcaa gcgggtcttc tacattgccc ccaactctct ttcttttgaa aaggaacgcg
      541 ccgtgctgga atgcttgtcc cagcaggctt ctttttctat taccgtcacg cgctttgctc
      601 aaatggctcg ttatctggtc ctgaatgatt taccagttaa aactactctt gatgatatcg
      661 gtcttgggtt ggccttttac aaatgccttg ccgaactcga tcccaaggac ttgcgtgttt
      721 atggcgctat taagcaggat cctcaattga tccagcagtt aattgagctt taccatgaga
      781 tgaccaaatc tcagatgagt tttttggact tggagaattt aacagatgag gataagagga
      841 cggatttact cttgattttt gagaaagtaa cagcctatct taatcaaggt cagttagccc
      901 agggaagtca gttgtcccat ttgattgagg ctattgagaa tgacaaggta agtagtgatt
      961 ttaatcaaat caccttggtc attgacggct ttactcgttt ttctgctgag gaagagcggg
     1021 ttgtggactt acttcacggc aaaggtgttg agattgttat cggggcttat gctagtaaga
     1081 aagcctatac cagtcctttt agcgagggca atctctacca agccagcgta aaatttctcc
     1141 atcatctggc ttctaaatac caaacgcctg ctcaggactg ttctcaaact catgagaaga
     1201 tggatagttt tgacaaggcc tctcgtttgt tggagtcttc ttatgacttt tcagaactcg
     1261 ctttggatgt cgatgagaaa gaccgtgaaa atttacaaat ctggtcttgt ttgacgcaaa
     1321 aggaggagtt ggagctagta gcccgtagca ttcgtcagaa attacatgag aactcagacc
     1381 tgagctacaa gcattttcgt attctcttgg gggatgtagc ttcttaccag ttatctctca
     1441 aaaccatttt tgaccagtat cagattcctt tttatcttgg tagaagcgaa gccatggctc
     1501 atcatccctt gactcagttt gtcgagtcta ttttagcttt aaaacgttac cgttttcgtc
     1561 aggaggattt gattaatctt cttagaactg atttgtatac tgacctcagt cagtctgata
     1621 ttgatgcttt tgagcaatat atccgctatc ttggtatcaa tggcttgcca gcctttcagc
     1681 aaatcttcac caaatcccac catggaaaat ttaatcttga gcgtttgaat gtcctccgcc
     1741 tgagaatttt agcacctctt gaaaccctct ttgccagccg aaaacaaaag gctgaaaacc
     1801 tcctacaaaa atggagtgtc tttctaaaag aaggagctgt gaccaagcag ttacaagatt
     1861 tgacaaccac tttggaagct gtagaacagg aaagacaagc cgaagtttgg aaggctttct
     1921 gccatgtttt agaacaattt gcgactgttt ttgctggttc acaggttagt ctggaagact
     1981 tcctagcctt gctccattct ggaatgagtt tgtcccaata ccgtaccatt ccagcaacag
     2041 tggacactgt tctggtgcag agttacgatt tgattgcacc attgactgct gactttgtct
     2101 atgctattgg actaactcag gacaatttac caaaaatttc tcaaaacacc agtcttctga
     2161 cagatgaaga aaggcaaaat ctaaaccaag cgaccgaaga aggcgttcaa ttactgattg
     2221 ccagcagtga aaatctcaag aaaaatcgct acactatgct ttccttggtc aattctgctc
     2281 gtaagcagtt gttcttgtcg gctccaagcc tttttaacga aagtgaaagt aaggaatctg
     2341 cctatcttca agagttgatc cattttggat ttaggcggag agagaagagg atgaatcaca
     2401 aaggactgtc taaggaggat atggggtcct atcacagtct tttgtctagt ctggttgcct
     2461 atcaccagca gggtgagatg agcgatactg agcaagattt gacttttgtc aaggttctgt
     2521 cgcgtgtcat aggtaaaaaa ctagatctgc aaggtctgga aaatccagct atcccaacca
     2581 gtccaagcag caagacctta gccaaggaca ccttgcaagc tctctatcct gccaaacagg
     2641 agttttacct gtctacgtcg ggtttgacag agttttatcg caatgaatac agttatttcc
     2701 tacgctacgt tttaggcttg caggaggaat tacgtttgcg tcctgatgcc cgtagtcacg
     2761 ggaatttctt gcatcgtatc tttgaacgcg ccttacagtt gcctaatgaa gattcctttg
     2821 accaacgtct agaacaagct attcaagaaa ccagtcaaga acgcgaattt gaagctattt
     2881 atcaagaaag tttggaagcc cagtttacca aggaagtttt gcttgatgtt gcacggacga
     2941 ctggacatat tctccgacac aatccagcca tcgaaaccat caaagaagaa gcaaattttg
     3001 gtggaaaaga ccaagccttt attcaattag acaatggacg cagtgtcttt gtacgaggca
     3061 aggtggaccg gattgaccgt ttgaaagcta atggagcgat aggagtagta gactacaaat
     3121 ccagtctgac tcagttccag tttcctcatt tctttaatgg gctcaattct cagttaccaa
     3181 cctatcttgc tgccctaaaa agagaagggg agcagaactt tttcggcgcc atgtacttgg
     3241 aaatggctga acctgtccaa tctctgatgg cggtaaaaag tctggcagga gcagtggtag
     3301 aagccagcaa atctatgaaa taccaagggc tcttcttgga aaaagaaagc agttatttag
     3361 gcgaatttta taacaaaaac aaggctaatc aactgacaga tgaggaattt cagctcctac
     3421 tggactacaa tgcctatctt tacaagaaag ctgctgagaa gattttagca ggccggttcg
     3481 ccatcaatcc ttatactgaa aatggcagaa gcattgcccc atacgtccag caacatcagg
     3541 ctattacagg ctttgaagcc aattaccatc tgggccaagc ccgtttccta gaaaagttgg
     3601 acctagctga tggcaagcgt ctggtcggag aaaaactcaa gcaagcttgg tttgaaaaaa
     3661 taagagagga gttaaatcga tgaagcttat tcccttttta agtgaggagg agattcaaaa
     3721 actgcaagaa gcagaagcaa attcgagcaa ggaacagaag aaaactgccg aacaaatcga
     3781 agctatctac acttctggtc agaatatcct ggtctcagca tcggctggtt ctggaaagac
     3841 ctttgtcatg gtagagcgca ttctggacca attggcgcgt ggtgtcgaaa tttctcaact
     3901 ctttatctca acctttaccg tcaaggctgc aactgaactt aaagaacgtt tagagaaaaa
     3961 aatcagcaag aaaatccaag aaacagatga tgtcgatctc aaacaacact tgggtcgcca
     4021 gttggcagac ctacccaacg ctgccatcgg aaccatggac tctttcacac aaaaattcct
     4081 tggcaaacat ggttatctgc ttgatattgc acctaatttc cgtattttac aaaaccaaag
     4141 cgagcaactt cttctcgaaa acgaagtctt tcatgaggtc tttgaagcgc attaccaagg
     4201 taaacagaaa gagaccttta gtcatttgct gaaaaacttt gctgggcgtg gcaaggacga
     4261 acggggtctg cgccagcagg tctataaaat ctatgacttc ctccaatcca ccagtaatcc
     4321 tcaaaagtgg ttgagtgaat ctttcctcaa aggctttgag aaagctgatt ttaccagtga
     4381 aaaagaaaaa ctgactgagc aaatcaaaca agccctttgg gatttggaaa gctttttccg
     4441 ttaccatctg gataacgatg ccaaggagtt tgcaaaggct gcctatttag aaaatgttca
     4501 gttaattctg gatgaaattg gctccctaaa tcaggagtcc gatagtcagg cttatcaggc
     4561 agtgcttgcg cgtgttgtcg ccatctctaa ggagaaaaac ggtcgagctc tgactaatgc
     4621 cagtcgtaag gctgatttga agcccctggc tgatgcctac aacgaagaga gaaagaccca
     4681 gtttgctaaa ctaggacaat tatcagacca gataaccatt ctcgactatc aagaacgtta
     4741 tcatcaagac acatgggaac tagctaaaac cttccaaacc tttatgagtc attttgtgga
     4801 ggcttatcgt cagcgcaaac gccaggaaaa tgcctttgaa ttcgctgata tcagccatta
     4861 caccattgag attttagaga atttcccaca agttcgtgag tcttatcagg agcgcttcca
     4921 tgaagtcatg gtcgatgagt atcaggatac caaccatatt caagaacgga tgctggaatt
     4981 gttgtctaat ggccacaatc gctttatggt gggagatatc aagcaatcca tctatcgttt
     5041 ccgtcaggca gacccgcaga ttttcaatga gaaattccaa cgctatgcgc aaaatcccca
     5101 aaaaggcaag ctcattctcc tcaaggaaaa tttccgtagt agttcagaag tgctgtcagc
     5161 aaccaatgat gtctttgaac gtctcatgga ccaagaggtc ggcgaaatca actatgataa
     5221 caagcaccag cttgtttttg ccaataccaa actgactccc aatccagaca acaaggcaga
     5281 atttctcctc tacgacaagg acgatacagg tgaggaagaa gagagtcaaa cagaaacgaa
     5341 actaacaggc gaaatgcgct tagttatcaa ggagattctg aaacttcatc aagaaaaagg
     5401 tgttgccttt aaggaaattg cccttctgac ctccagccgc agtcgtaatg accagattct
     5461 cctcgccctg tctgagtacg ggattcctgt caaaactgac ggagagcaaa acaattatct
     5521 ccaatcccta gaagtgcaag tcatgctaga cactcttcgt gtcattcaca atcccctgca
     5581 agactacgcc ttggttgccc ttatgaagtc tccaatgttt ggttttgatg aggatgagct
     5641 agcacgtttg tcccttcaga aagcagagga taaagtccac gaaaatctct atgagaaact
     5701 ggtcaatgca caaaaaatgg caagtagtca aaaaggcttg attcacacag ctctagctga
     5761 aaaactaaaa caattcatgg atatcctagc ttcttggcgc ttgtatgcca aaacccactc
     5821 tctctatgac ttgatttgga agatttacaa cgaccgtttt tattatgact atgttggggc
     5881 tttgccgaat ggtcctgcta ggcaggccaa tctctatgcc ctagcactgc gtgctgatca
     5941 atttgaaaag agcaatttca aaggtttgtc gcgttttatt cgtatgattg accaagtctt
     6001 agaagcccag cacgatttgg caagcgtggc cgtcgcaccg ccaaaagatg cagtagagct
     6061 catgaccatc cacaagagta aagggctgga gtttccttac gtctttatcc tcaatatgga
     6121 tcaagatttc aacaagcaag actctatgtc agaagtcatt ctcagtcgtc agaatggtct
     6181 tggtgtcaaa tatattgcca agatggagac aggggcagta gaagaccact atcctaaaac
     6241 catcaaactc tccattccta gtctgaccta taggcagaac gaagaggaat tacagctagc
     6301 aagctattct gagcagatgc gtttgctgta tgttgctatg acgcgggctg agaaaaagct
     6361 ctatcttgtc ggcaagggtt ctcgtgaaaa gctggaatcc aaggaatacc cagcagccaa
     6421 aaatgggaaa ctaaatagca atactagact gcaagcacgg aatttccaag attggctttg
     6481 ggctatcagt aaagtgttta ctaaggacaa gctcaacttt agttatcgtt ttattggcga
     6541 agatcagttg accagagaag ctatcggaga gttggaaacc aagagtcctc tccaagatag
     6601 ctcccaagca gacaatcgtc agtcagatac catcaaagaa gctctggaaa tgctgaagga
     6661 ggtggaagtt tataatactc ttcaccgcgc agctattgaa cttcctagtg ttcaaacccc
     6721 aagtcaaatc aagaaattct acgaaccagt tatggatatg gaaggtgtcg agattgctgg
     6781 tcaaggtcag tcagtaggca agaaaatcag cttcgatttg ccagattttt caaccaaaga
     6841 aaaggtaact ggagctgaga ttggtagtgc tactcacgaa ctcatgcaga gaattgacct
     6901 cagccagcaa ctaacccttg ctagcctaac agaaacactc aaacaagttc aaactagcca
     6961 agctgtcaga gacaagatca atcttgataa aattcttgct ttctttgaca cagtactcgg
     7021 tcaggaaatt cttgctaata ccgaccatct ttatcgcgag caacctttct ccatgctcaa
     7081 acgagaccaa aagagtcagg aagactttgt tgtccgtggt atccttgatg gctatctgct
     7141 ttacgaaaac aaaattgttc tgttcgacta caagacagac cgctatgatg aaccaagtca
     7201 actcgtagac cgctatcgtg gtcagttagc tctatacgaa gaggctttat cacgagccta
     7261 ttcgattgaa aatattgaaa aatacttgat tttactcggt aaagacgagg ttcaagttgt
     7321 aaaagtataa cttatactct ttgaaaatct cttcaaacca cgtcagcttc gccttgctgt
     7381 atatatggtt actgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagctga
     7441 ctgcggctag ctttctagtt tgctctttga tttttattga gtattagaaa ggagacctca
     7501 tgacacttcc agttagaaaa tccctgcacg atgcagtttt acaggcttcg aaagcggata
     7561 cttgggaaca agctaccaag gaatggaatg aagtttcctt tatttttaac ggtatcggcc
     7621 gtagcaattg tgtctgtgga aatgccatca aatacgctta tgaactcttt aacggtgtca
     7681 caggccaacg cctctttcca attggtagcg actgtgttcg tcattttcat cgattgtccc
     7741 ttgaccagca attggaagag gaagaaaaac tgctcagaaa ggttgaaaat ctaaccagaa
     7801 aagctcagaa aaaggaaaaa atcaaggtca ataaaagtaa ctttgacgag cgacttctaa
     7861 aatggctctg ggaaaaaggt gttttcaaac ccaatcgtgg caatcaattt gcgcctgaga
     7921 gagactacca gcttttccta gaagtctttc agggaggaag ttggaccaag gcggaaccaa
     7981 agaaaaaggc tcggatggaa gaagtccttg aaaagtgtat caaacccttt ttacttggga
     8041 aatcggatga ccaactctac cttgtcaagc taggcaagga gaaaattgac tacgaacaag
     8101 aactccgtat ccaggcagag aaagaacgca agaagaggga taaaatcgcc aagcaatatg
     8161 cagacaatct ggttctagcc atgggacccg cagagcgtgc ttatcaagat tactttggct
     8221 ttacagagac cctgactcaa gaagaacgca agtgggaaaa aattcttttt ggtaaaaata
     8281 gagcagaacg agctatcaag gccaaacaat accaaaaaga gctggaaaaa gaccaacgaa
     8341 ttgccagtca ggatccaatt gaaagaaaac agaagcagac ttggatcctc aattcctatt
     8401 ttcgtgagct tcctgaagaa aaagctcgat tttctagact cttattagaa tatcgaaaaa
     8461 gtggtgaagt acccttttca actgaatacc tgtcagatca tctcatcgac tttttctata
     8521 aaatgaaagc ctttgaattt gaaatcgcac cagaacaagt ccgagatttt ctaaaaaaaa
     8581 gcctgcagga agaccatcgc tcatcagcac aaggaagctg gatagaagga attctcctca
     8641 actgcctcaa accattttta gaacgattag tgatatgagt aacacctacc gtgtaaattt
     8701 catggtaggt gttattgtac ccccaaataa tataaaacaa agtatgaaag cgcatctcaa
     8761 ttttaagact tttttgtaaa ttaagagtat aattaaggta tactgccttt tctatagata
     8821 atagataata cactaatata ataaaggtct ttgtaacata tataaatttt atttcaagga
     8881 ggaataatgg aaaagtattt tggtgaaaaa caagagcgtt tttcatttag aaaattatca
     8941 gtaggacttg tatctgcaac gatttcaagt ttatttttta tgtctgtatt agctagttca
     9001 tctgtggatg ctcaagaaac tgcgggagtt cactataaat atgtggcaga ttcagagcta
     9061 tcatcagaag aaaagaagca gcttgtctat gatattccga catacgtgga gaatgatgat
     9121 gaaacttatt atcttgttta taagttaaat tctcaaaatc aactggcgga attaccaaat
     9181 actggaagca agaatgagag gcaagcccta gttgctggtg ctagcttagc tgctctggga
     9241 attttaattt ttgctgtttc caagaaaaag gttaagaata aaacggtatt acatttagta
     9301 ttggttgcgg gaatgggaaa tggtgtctta gtttcagtcc atgctttaga aaatcatctt
     9361 ttgctaaatt acaatacgga ctatgaattg acctctggag aaaaattacc tcttcctaaa
     9421 gagatttcag gttacactta tattggatat atcaaagagg gaaaaacgac ttctgatttt
     9481 gaagtaagta atcaagaaaa atcagcagcc actcctacaa aacaacaaaa ggtggattat
     9541 aatgttacac caaattttgt agaccatcca tcaacagtac aagctattca ggaacaaaca
     9601 cctgtttctt caactaagcc gacagaagtt caagtagttg aaaaaccttt ctctactgaa
     9661 ttaatcaatc caagaaaaga agagaaacaa tcttcagatt ctcaagaaca attagccgaa
     9721 cataagaatc tagaaacgaa gaaagaggag aagatttctc caaaagaaaa gactggggta
     9781 aatacattaa atccacagga tgaagtttta tcaggtcaat tgaacaaacc tgaactctta
     9841 tatcgtgagg aaactataga gacaaaaata gattttcaag aagaaattca agaaaatcct
     9901 gatttagctg aaggaactgt aagagtaaaa caagaaggta aattaggtaa gaaagttgaa
     9961 atcgtcagaa tattctctgt aaacaaggaa gaagtttcgc gagaaattgt ttcaacttca
    10021 acgactgcgc ctagtccaag aatagtcgaa aaaggtacta aaaaaactca agttataaag
    10081 gaacaacctg agactggtgt agaacataag gacgtacagt ctggagctat tgttgaaccc
    10141 gcaattcagc ctgagttgcc cgaagctgta gtaagtgata aaggcgaacc agaagttcaa
    10201 ccgacattac ccgaagcagt tgtgaccgac aaaggtgaga ctgaggttca accagagtcg
    10261 ccagatactg tggtaagtga taaaggtgaa ccagagcagg tagccccatt gccagaatat
    10321 aagggtaata ttgagcaagt aaaacctgaa actccggttg agaagaccaa agaacaaggt
    10381 ccagaaaaaa ctgaagaagt tccagtaaaa ccaacagaag aaacaccagt aaatccaaat
    10441 gaaggtacta cagaaggaac ctcaattcaa gaagcagaaa atccagttca acctgcagaa
    10501 gaatcaacaa cgaattcaga gaaagtatca ccagatacat ctagcgaaaa tactggggaa
    10561 gtgtccagta atcctagtga ttcgacaacc tcagttggag aatcaaataa accagaacat
    10621 aatgactcta aaaatgaaaa ttcagaaaaa actgtagaag aagttccagt aaatccaaat
    10681 gaaggcacag tagaaggtac ctcaaatcaa gaaacagaaa aaccagttca acctgcagaa
    10741 gaaacacaaa caaactctgg gaaaatagct aacgaaaata ctggagaagt atccaataaa
    10801 cctagtgatt caaaaccacc agttgaagaa tcaaatcaac cagaaaaaaa cggaactgca
    10861 acaaaaccag aaaattcagg taatacaaca tcagagaatg gacaaacaga accagagaaa
    10921 aaactcgaat taagaaatgt ttctgatatt gagttgtata gtcagacgaa tggaacctac
    10981 agacaacatg tttcattgga tggaattcca gagaatacgg atacttactt tgtcaaggta
    11041 aaatcttcag catttaaaga tgtctatata ccagtagctt caataaccga agagaaaaga
    11101 aatgggcagt cagtttataa aatcacagcc aaagctgaga aactccagca agaactagaa
    11161 aataaatatg tcgacaattt caccttctac ctcgataaga aggctaaaga ggaaaataca
    11221 aactttactt cctttagcaa cctggtcaaa gctataaacc aaaatccctc tggaacctat
    11281 catttagcgg ccagcctgaa tgctaacgaa gtggagcttg gtcctgatga aagatcctat
    11341 atcaaggaca cctttactgg tcgtttaatc ggtgaaaaag atggcaagaa ttatgctatc
    11401 tataatttga aaaaacctct gtttgaaaac ttgagtggtg ctacagtaga aaaactgagt
    11461 ctaaaaaatg ttgctatttc agggaaaaat gatattggtt cactggcaaa tgaagctacg
    11521 aatggcacaa agattaaaca agttcatgtt gatggtgttc tggctggaga acgtggtgtc
    11581 ggtggtttgt tggctaaggc agaccaatca agcatcgcag agagcagttt caagggaaga
    11641 attgtcaata cctatgaaac gactgatgcc tacaatattg gcggtctggt cggtcattta
    11701 acaggaaaaa atgcgtctat tgctaaatcc aaagcgacag taaccatttc gtcaaacacc
    11761 aataggtcag atcagactgt cggtggtctt gcaggtctag tagaccaaga tgcgcatata
    11821 cagaacagtt atgcggaagg tgatattaat aatgtcaagc actttggtaa agtcgctggt
    11881 gtggcaggat atttgtggga tcgaacttct ggtgaggaaa aacacgctgg tgaattgacc
    11941 aatgttctta gcgatgtcaa tgtaacaaac ggaaatgcca tcactggata ccactataca
    12001 ggaatgaagg tagctaatac atttagtagt aaggctaata gagttttcaa tgtcacttta
    12061 gagaaggatg aggtcgtcag caaggaatcc tttgaagaaa gaggaacaat gctagatgct
    12121 tctcaaattg taagcaaaaa agcagaaata aatcctctca ctctaccaac ggtggaaccc
    12181 ctctcaacaa gtggcaagaa agacagtgat ttttctaaga tagcccatta tcaagctaac
    12241 cgtgctttgg tttataagaa cattgaaaaa ttgttacctt tttataataa gtcaaccatc
    12301 gtcaaatacg gaaacctggt taaggagaac agtctcttat accaaaaaga actcttatct
    12361 gcagttatga tgaaggatga ccaagtaatc acagatattg tttccaacaa acagactgca
    12421 aacaaactct tacttcacta taatgaccat tcatctgaga aatttgatct caagtaccag
    12481 actgattttg ccaatctagc agaatataat ctaggtaata cgggacttct ctacactcct
    12541 aaccaattct tatatgatcg agactctatt gttaaggaag tcttgcctga gttgcagaag
    12601 cttgattacc agtcagatgc tatcagaaag acacttggta tttctccaga agttaagtta
    12661 accgagctct atttagaaga ccagttctcc aaaacaaaac aaaatctggg agacagcttg
    12721 aaaaaacttt tgtcagcaga tgccggtcta gctagcgata actcagtcac cagaggctat
    12781 cttgtagata aaatcaagaa taataaggaa gccttgctac tcggtttaac ttatttagaa
    12841 cgttggtata actttaacta tggtcaagtg aatgtcaaag acctagttat gtatcatcca
    12901 gacttctttg gtaaaggaaa tacttcccca ctagatactc tgattgagtt aggtaaatct
    12961 ggctttaaca atcttctagc taagaataat gtcgatactt atggtatcag tcttgccagt
    13021 caacatggag cgacagattt gtttagcacg ctggaacatt accgaaaagt ctttttacca
    13081 aatacaagca ataatgactg gtttaaatca cagactaagg cttacattgt cgaagaaaaa
    13141 tccactatcg aagaggtgaa aacgaagcaa gggttagctg gcaccaagta ttctatcggt
    13201 gtttatgatc gtatcacgag tgccacatgg aaataccgca atatggtctt gcctctcctg
    13261 accttgccag agagatccgt atttgtcatc tcgaccatgt ctagtctagg atttggagct
    13321 tatgatcgct accgcagtag tgaccataaa gcgggcaagg ctctcaatga ttttgttgaa
    13381 gaaaatgcgc gtgaaacagc caaacgtcag cgagatcact acgattattg gtatcgtatt
    13441 ttagatgaac agtcacgcga aaaactctat cgtacgattc tcctttatga tgcctataag
    13501 tttggggatg acacaacatc aggaaaagct acagcggagg ctaagtttga tagctccaat
    13561 ccagctatga agaacttctt tggaccagtt ggcaataagg tagtacacaa ccagcatgga
    13621 gcctacgcta caggggacgg cgtctactat atgtcttacc gcatgctgga caaggatgga
    13681 gccattactt atacccatga aatgacccat gattcggatc aggatattta ccttggtggc
    13741 tatggtcgaa gaaatggctt gggaccagag ttcttcgcaa aaggcttatt gcaagcccct
    13801 gaccaaccaa gtgacgcaac cattaccatt aattctatct tgaaacactc aaaatcagat
    13861 agtacagagg gatcccgtct tcaagtcttg gatccgacag agagattcca aaacgcagca
    13921 gatcttcaga actatgtcca taacatgttt gaccttatct acatgatgga atatctcgaa
    13981 gggcagtcaa tcgttaataa actaagtgtt taccagaaaa tggcggctct cagaaaaatt
    14041 gagaacaagt atgtgaaaga tccagcagat ggaaatgagg tttatgccac taacgtagtc
    14101 aaagaattga cagaagcaga ggcccgaaac ctgaatagtt ttgaaagttt gattgaccac
    14161 aacatcttat cagctcgtga gtaccagtct ggcgactatg aacgaaatgg ctactatacc
    14221 atcaaactct ttgccccaat ctattcagct ctcagcagtg agaaaggcac accaggggac
    14281 cttatgggac gtaggattgc gtacgaactt ttggctgcca aaggctttaa ggatggaatg
    14341 gtaccttata tctcaaacca atacgaagaa gatgctaaac aacaagggca aactatcaat
    14401 ctttatggta aagaacgggg cttggtgacc gatgagcttg ttttgaaaaa ggtatttgac
    14461 ggtaagtata aaacttgggc agaatttaag acagctatgt accaagaacg ggtggatcag
    14521 tttggaaact tgaagcaggt gacctttaaa gatccgacaa aaccatggcc aagctatggc
    14581 acaaagacta tcaataatgt ggatgaattg caagccctca tggaccaagc tgttctcaag
    14641 gatgctgaag gttcacgttg gagtaattat gatccagaaa tcgacagtgc cgttcataag
    14701 ttgaagagag caatctttaa agcctatctt gaccaaacaa atgattttag aagttcaatt
    14761 tttgagaata aaaaatagtg tttactatta ggaaataaag tttaaaaagg tgatgaagaa
    14821 caaaccaaga ttcaagcagg aattcctact gataatgaag taagttatgc tcttatttat
    14881 cagcaggaaa ctcttcctgc aacaggttca tcaacttctg cacttacagc tttaggccta
    14941 ttagctgttg gtagtttagt tcttttggtt cacaatatga cgggaacagt tttttgctcc
    15001 ctctgaaaag tcatcatttg atggcttttt tctatatagg gtaaaagata gggtaaaagg
    15061 ctatcatcgg acaaaataaa gaaggcatga tataatataa agtagatttc tatgtcataa
    15121 aacaagaact gtttggacat catccatttg aagactctct atgttcaaac tatagtaaaa
    15181 taaaataggg gatctaaatc cttgctacga aaggaaaaaa ctcaatggct actattcaat
    15241 ggtttcctgg tcacatgtct aaagcgcgtc gacaggtgca ggaaaattta aaatttgttg
    15301 attttgtgac gattttagta gatgcacgct tgcctctatc tagtcaaaat cctatgttga
    15361 ccaagattgt tggtgataaa ccaaaactct tgattttaaa caaggccgac ttggctgatc
    15421 cagcaatgac caaggaatgg cgtcagtatt ttgaatcaca agtaatccag acgctagcta
    15481 tcaactccaa agagcaagtg actgtaaaag ttgtaacaga tgcggccaag aagctcatgg
    15541 ctgataagat tgctcgccag aaagaacgtg ggattcagat tgaaaccttg cgtaccatga
    15601 ttatcgggat tccaaacgct ggtaaatcaa ctctgatgaa ccgtttggct ggtaaaaaga
    15661 ttgctgttgt tggaaacaag ccaggggtca caaaaggtca acaatggctt aaaaccaata
    15721 aagatctgga aatcttggat acaccgggga ttctctggcc taagtttgag gatgaaactg
    15781 ttgcacttaa gttggcattg actggagcta tcaaggatca gttgcttcct atggatgagg
    15841 ttaccatttt tggtatcaat tatttcaaag aacattatcc agaaaagctg gctgaacgct
    15901 tcaaacaaat gaaaattgaa gaagaagcgc ctgtgattat tatggatatg acccgcgccc
    15961 tcggtttccg tgatgactat gaccgttttt acagtctctt cgtgaaggaa gtccgtgatg
    16021 gcaaactcgg taactatacc ttagatacat tggaagacct cgatggcaac gattaaagaa
    16081 atcaaagaac tccttgtgac agtcaaggag ttagaaagcc ctattttttt agagcttgaa
    16141 aaggataatc gctcaggagt tcaaaaggaa atcagcaagc gtaaaagagc cattcaagct
    16201 gaattagatg aaaatttgcg cttggaatcc atgctttctt atgaaaaaga actttataag
    16261 caaggattga ccttaattgt aggtattgat gaggttggtc gtggtcctct tgctggtcct
    16321 gtagtcgctg cggccgtcat tttacctaaa aattgtaaga ttaaagatct caacgacagc
    16381 aagaaaattc ctaaaaagaa acatctggag attttccaag ccgttcaaga ccaatccttg
    16441 tcgattggaa ttggtatcat agataatcag gtcatcgacc aagtcaacat ctatgaagca
    16501 accaaactag ccatgcaaga agcaatctcc cagctcagcc ctcaaccaga gcaccttttg
    16561 attgatgcca tgaaactgga cttgcccatt tcacaaacct ccattatcaa aggagatgcc
    16621 aactccctct ctatcgcagc agcatctata gtagccaagg taacacgtga tgaattgatg
    16681 aaggaatacg atcagcagtt ccctggctat gatttcgcta ctaatgcagg atatggcaca
    16741 gctaaacatc tggaaggcct cacaaaacta ggagttaccc caattcaccg aaccagcttt
    16801 gaacccgtta aatcactggt tttaggtaaa aaagaaagtt aattgaaagg aaataccatg
    16861 gaggaacagt cggaaatagt ccgttctaag aaagaattcg cctttgcatc cagcactata
    16921 ctatcccaag ttggtcgagg aatcattatc ggcctcatcg ttggaattat cgtcggatcc
    16981 tttcgtttct taattgaaaa gggcttccac ctgatacaag gagtttatca agatcaaggg
    17041 tacttagtgc gcaatctttt tgtactggtt ttgttttata tactcatctg ttggctcagt
    17101 gccaaactaa cacggtcaga aaaagatatt aaaggctcag gaattcctca agtcgaagcc
    17161 gaactgaaag gcctcatgtc cctcaactgg tggggcattc tttggaaaaa atatgtgcta
    17221 ggtattcttg ctattgccag tggactcatg ctgggtcgag agggacccag cattcaactt
    17281 ggagcagttg gtggtaaagg aattgccaag tggctcaaat ccagtccagt agaggaacgt
    17341 tccttgattg ccagtggagc tgcagcaggt ttagccgcag cctttaatgc tcctattgca
    17401 gcacttctct ttgttgtaga agaagtctat caccattttt cgcgcttttt ctgggtctca
    17461 actctagcag ccagcatcgt agcaaacttt gtgtctctac tcatgttcgg tttgacacca
    17521 gtattggata tgccagataa cattcctccc atgaccctag accagtattg gatatatctc
    17581 gtcatgggaa ttttccttgg attttcaggt tttctctatg agaaagctgt attaaacgtt
    17641 ggaagagttt atgacttgat tggtcaaaaa atccatttgg atagggctta ttatcccatc
    17701 ttggctttta tccttatcat accagtcgga atcttcttac ctcaaatcat tggtggcgga
    17761 aatcagcttg tcctttcttt aactgaacaa aattttagtt tccaagtttt attagcttac
    17821 tttttaatcc gctttatttg gagtatgatt agctatggaa gtggactgcc aggaggaatt
    17881 ttcctcccca ttttagctct tggttctttg cttggtgcct tagttggtgt tatctgtgtc
    17941 aatcttggac ttgtcagtca agagcaattc cctatatttg tcattctagg aatgagtggc
    18001 tattttggag ccatatcaaa agctccctta accgctatga tcctcgtaac tgagatggta
    18061 ggagatattc gcaaccttat gccacttggt cttgtcactc ttgtttctta tattatcatg
    18121 gatttgctca aaggtacgcc agtctatgaa gccatgctgg aaaaaatgct tccagaagaa
    18181 gtatctagcg aaggagaagt tacacttatc gaaataccag tttctgataa aattgctggg
    18241 aaacaagttc atgaactcaa cttaccacac aacgtcctca tcacaactca agtccataat
    18301 ggcaagagcc aaacagttaa cggctcaacc agaatgtatc tgggtgatat gattcacctg
    18361 gttattccaa aaagtgaaat tggaaaagtc aaagatttgt tgttgtagta tgatcattta
    18421 cataatttat gttatgtaaa tgatcagttt gatttattta gaaaaccgat tctcagaa
//
LOCUS       DAVLTT010000041        17279 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLTT010000041 DAVLTT010000000
VERSION     DAVLTT010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17279
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.041"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..138
                     /locus_tag="VYN15_001472"
     CDS             <1..138
                     /locus_tag="VYN15_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1452777.1"
                     /translation="RSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELG
                     F"
     gene            329..2620
                     /gene="pcrA"
                     /locus_tag="VYN15_001473"
     CDS             329..2620
                     /gene="pcrA"
                     /locus_tag="VYN15_001473"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV1452778.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWNFANMMLDLREQLDHLSITELVESVLEKTGYVDILNTQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2663..3343
                     /gene="radC"
                     /locus_tag="VYN15_001474"
     CDS             2663..3343
                     /gene="radC"
                     /locus_tag="VYN15_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV1452779.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3340..4029)
                     /locus_tag="VYN15_001475"
     CDS             complement(3340..4029)
                     /locus_tag="VYN15_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1452780.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKIIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4047..4688)
                     /locus_tag="VYN15_001476"
     CDS             complement(4047..4688)
                     /locus_tag="VYN15_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV1452781.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDNHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4771..4986)
                     /locus_tag="VYN15_001477"
     CDS             complement(4771..4986)
                     /locus_tag="VYN15_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1452782.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4994..5341)
                     /locus_tag="VYN15_001478"
     CDS             complement(4994..5341)
                     /locus_tag="VYN15_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV1452783.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5346..6461)
                     /locus_tag="VYN15_001479"
     CDS             complement(5346..6461)
                     /locus_tag="VYN15_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1452784.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIP
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6471..7430)
                     /locus_tag="VYN15_001480"
     CDS             complement(6471..7430)
                     /locus_tag="VYN15_001480"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1452785.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7543..8112)
                     /locus_tag="VYN15_001481"
     CDS             complement(7543..8112)
                     /locus_tag="VYN15_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV1452786.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8240..8911
                     /locus_tag="VYN15_001482"
     CDS             8240..8911
                     /locus_tag="VYN15_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV1452787.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8895..9713
                     /locus_tag="VYN15_001483"
     CDS             8895..9713
                     /locus_tag="VYN15_001483"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV1452788.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9710..10606
                     /locus_tag="VYN15_001484"
     CDS             9710..10606
                     /locus_tag="VYN15_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1452789.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     DIRLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLDDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10650..11624
                     /gene="pta"
                     /locus_tag="VYN15_001485"
     CDS             10650..11624
                     /gene="pta"
                     /locus_tag="VYN15_001485"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV1452790.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(11965..12264)
                     /locus_tag="VYN15_001486"
     CDS             complement(11965..12264)
                     /locus_tag="VYN15_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV1452791.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVIDPEDLETLSDTTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            12666..13364
                     /locus_tag="VYN15_001487"
     CDS             12666..13364
                     /locus_tag="VYN15_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV1452792.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIGFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     misc_feature    13429..13516
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            13552..13866
                     /gene="rplU"
                     /locus_tag="VYN15_001488"
     CDS             13552..13866
                     /gene="rplU"
                     /locus_tag="VYN15_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV1452793.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            13882..14226
                     /locus_tag="VYN15_001489"
     CDS             13882..14226
                     /locus_tag="VYN15_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV1452794.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            14243..14536
                     /gene="rpmA"
                     /locus_tag="VYN15_001490"
     CDS             14243..14536
                     /gene="rpmA"
                     /locus_tag="VYN15_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV1452795.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(14741..14946)
                     /locus_tag="VYN15_001491"
                     /pseudo
     CDS             complement(14741..14946)
                     /locus_tag="VYN15_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1980 domain-containing protein"
     gene            15384..16301
                     /locus_tag="VYN15_001492"
     CDS             15384..16301
                     /locus_tag="VYN15_001492"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV1452796.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            complement(16394..17242)
                     /locus_tag="VYN15_001493"
     CDS             complement(16394..17242)
                     /locus_tag="VYN15_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1452797.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
BASE COUNT         5143 a         3191 c         3651 g         5294 t
ORIGIN      
        1 agaagcaagg ttgagaacat ctttgccaaa gtaaaaacgt ttaaaatgtt ttcaacaacc
       61 tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt tgagtgctgg tattatcaat
      121 catgaactag gattctagtt ttgcaggaag tctattgagg tattgagcta gtttatgaaa
      181 aaattgggtg aaaagtcgag tgttttagaa acccacagtg tagtattcta gtttcaatcc
      241 actatatttt gctactcccc gtaaagtttc tattttccct gatttctgat ataatagaaa
      301 tattgacttc aagagtaagg aagagaagat gaacgcatta ttaaatggaa tgaatgaccg
      361 tcaggctgag gcggtgcaaa cgacagaagg tcccttgcta atcatggcag gggctggttc
      421 tggaaagact cgtgttttaa cccaccgtat cgcttatttg attgatgaaa agctggtcaa
      481 tccttggaat atcttggcca ttacctttac caacaaggct gcgcgtgaga tgaaagagcg
      541 tgcttatagc ctcaatccag ctactcagga ctgtctgatt gcgaccttcc actccatgtg
      601 tgtgcgtatt ttgcgtcgcg atgcggacca tattggctac aatcgtaatt ttacaattgt
      661 ggatcctggt gaacagcgaa cgctcatgaa acgtattctc aaacagttga acttggatcc
      721 taaaaaatgg aatgaacgaa ctattttggg gaccatttcc aatgctaaga atgatttgat
      781 tgatgatgtt gcttatgctg cccaagctgg cgatatgtat acgcaaattg tggcccagtg
      841 ttatacagcc tatcaaaaag aacttcgtca gtctgaatcc gttgactttg atgatttgat
      901 tatgctgacc ttgcgtctct ttgatcaaaa tcctgatgtt ttgacctact accagcaaaa
      961 attccaatac atccacgttg atgagtacca agataccaac cacgctcagt accaattggt
     1021 caaactcttg gcttcccgtt ttaaaaatat ctgtgtggtt ggggatgcgg accagtctat
     1081 ctacggttgg cgtggtgctg atatgcagaa tatcttggac tttgaaaagg attaccccaa
     1141 agccaaggtt gttttgctgg aggaaaatta ccgctcaacc aaaaccattc tccaagcggc
     1201 caacgaggtt attaaaaata ataaaaatcg ccgtcctaaa aatctctgga ctcaaaacgc
     1261 tgatggggag caaatcgttt actatcgtgc cgatgatgag ctggatgagg ctgtatttgt
     1321 agccagaacc atcgatgaac ttagtcgcag tcaaaacttc cttcataagg attttgcagt
     1381 tctctatcgg actaatgccc agtcccgtac aattgaggaa gccctgctca agtctaacat
     1441 tccttatacc atggttggcg gaaccaaatt ctacagccgt aaggaaattc gcgatattat
     1501 tgcttatctc aaccttattg ctaatttgag tgacaatatt agttttgagc gtattatcaa
     1561 cgagcctaaa cgtggaattg gtctaggtac agttgagaaa atccgtgatt ttgcaaattt
     1621 gcaaaatatg tctatgctgg atgcttctgc taatattatg ttgtctggta tcaagggtaa
     1681 ggcagcccaa tctatctgga attttgccaa tatgatgctt gatttgcggg agcagctaga
     1741 ccacttaagc attacagagt tggttgagtc cgtcctagaa aaaacaggtt atgtcgatat
     1801 tcttaacacc caagcgactc tagaaagcaa ggcaagggtt gaaaatatcg aagagtttct
     1861 ttctgttacg aagaactttg atgacaccac tgatgtgaca gaagaggaaa ctggtctgga
     1921 caaactgagt cgtttcttaa atgacttggc tttgattgcc gacacagatt caggtagtca
     1981 ggagacatca gaagtgacct tgatgaccct gcatgctgcc aaaggtctcg aatttccagt
     2041 tgtctttttg attgggatgg aagaaaatgt ctttccactt agtcgtgcga ctgaagatcc
     2101 agatgaatta gaagaagagc gccgtctagc ctatgtaggt atcacgcgtg cagagaaaat
     2161 tctctatctg accaatgcca actcacgctt gctttttggt cgtaccaatt ataaccgtcc
     2221 gactcgtttt attaacgaaa tcagttcaga cttacttgag tatcaaggtc tggctcgtcc
     2281 tgcaaataca agctttaagg catcatatag cagtggtagt atttcctttg gtcaaggtat
     2341 gagtttggct caggctcttc aagaccgtaa acgcggtgct gccccaaaat caatccagtc
     2401 aagcggtctt ccatttggtc aatttacagc tggcgcaaaa tcagcatcta gcgaggcaaa
     2461 ttggtccatt ggtgacattg ctctccacaa gaaatgggga gagggaaccg ttctggaagt
     2521 ttcaggtagc ggtgctaggc aggaattgaa aatcaatttc ccagaagtag gtttgaaaaa
     2581 acttttagcc agtgtggctc caattgagaa aaaaatctaa ttttccatcc ttctcacgaa
     2641 taataaagtg aggaggattt ttatgtacag tatttcattc caagaagatt cactattacc
     2701 aagagaaagg ctggccaagg aaggagttga agcgcttagt aaccaagagt tgctagctat
     2761 tttactcagg acaggaacac gtcaagctag cgtttttgaa attgcccaaa aagtcttgaa
     2821 caatctttca agcctaacgg atttgaaaaa aatgaccctg caggaattgc agagtttgtc
     2881 tggtattggg cgtgttaagg ccatagaatt acaagctatg attgaactgg ggcatcgtat
     2941 tcacaaacac gagactcttg aaatggaaag tattctcagc agtcaaaagt tggccaagaa
     3001 gatgcagcag gaattagggg ataaaaaaca agagcacctg gtggcactct atctcaatac
     3061 tcaaaatcaa atcatccatc agcagaccat ttttatcggt tctgtaactc gtagtatcgc
     3121 tgaaccgcga gagattctgc actatgcaat caagcatatg gcgacttctc ttatcttggt
     3181 ccacaatcat ccttcaggag cggtagcgcc tagccaaaat gatgatcatg tcactaaact
     3241 tgttaaagaa gcctgcgaac tgatggggat tgttctcttg gaccatttga ttgtctctca
     3301 ttctaattac tttagttatc gtgaaaagac agatttaatc taaagttcat taacgacata
     3361 gtcaaagagt ttcttatctt tgggacgatt ttcaaaaaga agttctggat gccattggac
     3421 accgagaaag gcgacatcat ccgtactcat gacagcctca atgataccat ctttaggatc
     3481 atgagccaca acttttaaat ttggtgctaa gtccttgatg ctctggtggt ggaaggagtt
     3541 gatatgagag atttctccat agatttcttg gagaacggta tctggttctg tcaccaagcg
     3601 ttgagttgtg tactcaacag aagaatcctg ccaatggtct tcgatatctt ggtacaaagt
     3661 tccacccatg gcaacgttaa agagttgggt accacggcag acagagaaaa tgggcttttt
     3721 ctgtttaata gcttccttga tgagggccag ttcgaagata tctctttgaa ggtgatagtc
     3781 atcgctatca atgattttgg gttcgccata aaattttgga tcgacatttt gcccacctgt
     3841 caagatgagc ttgtcaatca aactgatata gtggcaggcc atttcttgat caccaatcgg
     3901 taggatgatg ggaatccctc cagcatcttt aacgccttca acaaagcctt ttgctgcgta
     3961 gctcatcatg atgtcatcat ctggatgagt tttttcgttt cctgtaatcc caataactgg
     4021 ttttttcata aaatgatttt cgctttctaa tcctcttttc gcatgaagta gaggagggtt
     4081 tggagttcac ttgtcaaatc gacatactga acgaccacgt cttttggtaa atgcagatgg
     4141 actggtgaaa aactgagaat tcctttcaca ccagcatcaa ccaagagatt agcaacctct
     4201 tgtgacttga cactgggaac agttaggata gcagtcttca catcagcatc cttgatttta
     4261 tccttgatct gagaaattcc gtaaatggga atcccgtcag gagtttgggt accgacttca
     4321 ggatggttat ctaggtcaaa ggccatgata atcttcatct tgttacgttc gtggaagcgg
     4381 tagtggagaa gggcatggcc catatttcca ataccaacca gcatgacatt ggtgatggag
     4441 ttatcattga gcaaatcggc aaaaaatgtc attagttttt tgacatcata gccaaaacca
     4501 cgacgaccaa gttcaccaaa ataggaaaaa tcacgacgta cggtcgctga atcaatccca
     4561 atggcctctg caatttgctt agaattggca cgttcaatct tttctgcatg aaatctctta
     4621 aaaattcgat agtagagaga gagtcttttt gctgtagctt ttggaatagc aaactgttta
     4681 tctttcacaa aatcacaacc tttctattct tctattttat agaaacattg tgaaaaaatc
     4741 aacaaaaata agaaaaaact aagaaaaatc ttagttttga tgtaaaaaat ctgcatgaga
     4801 tagaaaacgg tagaggtctc cgaccagacc ctgataaact ttttggcccc taaaagtcag
     4861 agaagtcaca taaagtgtat ctggtaaggt tacacatcct gacaaagtca acatgagagc
     4921 ctcatgatcc tcatacttga gagtacgctc tacatgatag cagtccttat aggtcagttc
     4981 aaacattttg gctctatctt tccgattttg taaagacacc acgttctacc aagctatcca
     5041 tgaggaagta gaatttttcc tgatgaatat ggtggtcttc tgatttgaaa atatcaacta
     5101 gacgaaggcc aaacttgtca gtgatattga ttttagcccc tgtaagttcc ttgttaatga
     5161 tgattttgag ttggaagcct tcaccgctgt ttggcacttt ttccaaaagg cgagtcagtt
     5221 catagttacc aaccttagtt tcaaaaaagg tgttatcttt gagggtgaat tttttaacag
     5281 aagggctaag agtgtaatcg taacgacaat tttttaactg aatgattttt tcaaatgcca
     5341 tatggctaac ctccgataat ttcttttaag gtttttgcga gggtttgtag gtcttcaacg
     5401 gtattttgtg gcgacaaact gatgcgaagg gattccttca agcgttctga atttgcgcca
     5461 tacatggctt caagaacatg gctggattgg acaacgcctg cagtacaggc tgagccagta
     5521 gagattgaaa ttccagctaa atctagccga aggagtaaga ggtcattttt ctgaccagga
     5581 aatccaatat tgagaacata agggagatga tgttttcctc tattcaggta atacggaatg
     5641 ccctccagct ctgccagaaa ggcagtttct agattttgta catgttgaaa atgttcttct
     5701 tgtttttcta ggtcttcttt tagggctgca accatgccta cgatggcagg cagattttca
     5761 gttcctgcac gttttttctg ttcctggtct ccgccatgta gataggaatc aaagtccatg
     5821 ctagatgcgt agagaaaacc gattccctta ggaccatgga atttgtgggc agaagcagtg
     5881 agaaaatcaa tgcccaattc ttctgaatga attgggattt taccaatagc ctgaactgca
     5941 tcaacatgat aggcagcagg gtgttgcttg agtatttggc caatttcagc gatgggcagt
     6001 aggtttcctg tctcattatt ggcaaacatg gtagaaacca aaatcgtatc gtcacgtaaa
     6061 gccttttgaa tttgctgggc tgtgatttct tgattttctg gctggataat ggttgcttca
     6121 aacccaaagt gttgaaccaa gtaatcaatt gtttcaagga cagcatggtg ctcgatggca
     6181 gttgtgatga tatgttttcc ttgttcttgg tgacgaagac agtagccaat gatggtagta
     6241 ttattgcctt cagtcccacc agaagtgaaa aagatatgtt gaggttttgt ccttagtaac
     6301 tgggctagtt cctgacgggc ttctcgcaag agtttgccag cttgacgacc atgaccatga
     6361 atactagaag gatttccgtg ggtttcttgc ataaccttgg tcatagctga aatagcaact
     6421 gctgacatag gagtcgttgc agcattgtcc aaataaatca aagaatcacc ttatttcttt
     6481 ttattgtagg caaagagtgg gctgactggt tttctttcgt gaatacggac gatagcatcg
     6541 ccaattaact cactagcagt gatgtagcat acatttttag gagttttttc ttttgttgct
     6601 actgaatcag tcacaagaat ttctttaata ttagtattgt caagaagctc agcagctccc
     6661 tcgacgaaga gaccgtggct agaaacagca taaatttctg tagctccttc acgttcaacg
     6721 attttagaag cttcagagaa ggtacgtcct gtatttaaaa tatcatcaat caagatagct
     6781 ttcttacctt caacatcacc aataatataa ccttcgttac gagttgcatc gtcttgaggg
     6841 tagtcgataa tggcgatagg agcatcaaga tattcagcca ggctacgcgc acgtttgaca
     6901 cctgaatttt tagggctaac gacaacaaca tctgaaccaa gcaatccttt atcgcagtaa
     6961 tgttttgcga ataggggaac agtgaaaaga ttatccactg gaatatcaaa gaaaccttga
     7021 acctgaacgg catgcaaatc aagagtcagg atacgatcaa ctccagcctt aaccagcata
     7081 ttggcaacta gttttgctgt aagtggctca cgaggacaag caatgcggtc ttgacgtgca
     7141 tagccaaaat atggaaggac aacgttgata ctgtgggcac ttgcacgcac acaagcatcg
     7201 accatgatta acaattccat taggtggttg ttgacaggga aacttgttga ttggatgatg
     7261 taaacatcat aaccacggac actttcttcg atatttactt ggatttctcc gtctgaaaat
     7321 tgacgtgatg atagttttcc aagtgggaca ccaacagctt gggcaatttt ctgtgcaatc
     7381 tcttggttag agttgagtgc gaaaagtttc atgttttttc tatctgacat tatagaccgt
     7441 cctctgtaaa ctttataaat cctagttata tttaccttac atatatgaac tagggtttgt
     7501 gtatttttat cttttctatt ttaccaaaaa atggagatta tttcagctat ttttcatact
     7561 tttgacaaat cgaaccaatt ttgaaggagc tttttgatag gaaatctgat ttttctctaa
     7621 aaattgtcgg aaatcctgtt tgccttgctc atgattttcc acttcaagct ccaattcgta
     7681 atctgttata tcaaagtatc ggctctgatc cagtgccatg agaccaatag ctgttttcat
     7741 ttcatagcga agcgttgtta gacaaccaag aacctgccag ttcttacttt ggataccatg
     7801 tttcgccaat tcatccagta ctagcccttg aggaagttct tccttactca gatagttctc
     7861 agcatctttt agttgcaatt tttggttgta ttccatgttt ccaacactct gcgggacttt
     7921 gagtgtcaac tcagcccagt cttcaaaggt tcgaatgcgc atagcgactt tcttttctcg
     7981 cagttcaaaa tcaggcgtgt cgatgtagta atttgtttga agaacaggag tgacacctgt
     8041 gaactggtct tttagacgat tgtattcatc ttttttcaat agtgttttca attcaatttc
     8101 taaatgtttc atttttctta ccttttttta tcgttgaaag cggatttatg gtataataag
     8161 cattgtattt attgtatatg aatctggaga aaaaatcaaa gatatttttg acggataata
     8221 tgagaacaag ggagaatata tgaccttaga atgggaagaa tttctagatc cttacattca
     8281 agctgttggt gagttaaaga ttaaacttcg tggtattcgt aagcaatatc gtaagcaaaa
     8341 taagcattct ccaattgagt ttgtgaccgg tcgagtcaag ccaattgaga gcatcaaaga
     8401 aaaaatggct cgtcgtggca ttacttatgc gaccttggaa cacgatttgc aggatattgc
     8461 tggcttacgt gtgatggttc agtttgtaga tgacgtcaag gaagtagtgg atattttgca
     8521 caagcgtcag gatatgcgaa tcatacagga gcgagattac attactcata gaaaagcatc
     8581 aggctatcgt tcctatcatg tggtagtaga atatacggtt gataccatca atggagctaa
     8641 gactattttg gcagaaattc aaattcgtac tttggccatg aatttctggg caacgataga
     8701 acattctctc aactacaagt accaagggga tttcccagat gagattaaga agcgactgga
     8761 aattacagct agaatcgccc atcagttgga tgaagaaatg ggtgaaattc gtgatgatat
     8821 ccaagaagcc caggcacttt ttgatccttt gagtagaaaa ttaaatgacg gtgtaggaaa
     8881 cagtgacgat acagatgaag aatacaggta aacgaattga tctgatagcc aatagaaaac
     8941 cgcagagtca aagggttttg tatgaattgc gagatcgttt gaagagaaat cagtttatac
     9001 tcaatgatac caatccggat attgtcattt ccattggcgg ggatggtatg ctcttgtcgg
     9061 cctttcataa gtacgaaaat cagcttgaca aggtccgctt tatcggtctt catactggac
     9121 atttgggctt ctatacagat tatcgtgatt ttgagttgga caagctagtg actaatttgc
     9181 agctagatac tggggcaagg gtttcttacc ctgttctgaa tgtgaaggtc tttcttgaaa
     9241 atggtgaagt taagattttc agagcactca acgaagccag catccgcagg tctgatcgaa
     9301 ccatggtggc agatattgta ataaatggtg ttccctttga acgttttcgt ggagacgggc
     9361 taacagtttc gacaccgact ggtagtactg cctataacaa gtctcttggc ggtgctgttt
     9421 tacaccctac cattgaagct ttgcaattaa cggaaattgc cagccttaat aatcgtgttt
     9481 atcgaacact gggctcttcc attattgtgc ctaagaagga taagattgaa cttattccaa
     9541 caagaaacga ttatcatact atttcggttg acaatagcgt ttattctttc cgtaatattg
     9601 agcgtattga gtatcaaatc gaccatcata agattcactt tgtcgcgact cctagccata
     9661 ccagtttctg gaaccgtgtt aaggatgcct ttatcggtga ggtggatgaa tgaggtttga
     9721 atttatcgca gatgaacatg tcaaggttaa gaccttttta aaaaagcacg aggtttctaa
     9781 gggattgctg gccaagatta agtttcgagg tggagctatt ctggtcaata atcaaccgca
     9841 aaatgcaacg tatctattgg acgttggaga ctacgttacc attgacattc ccgctgagaa
     9901 aggctttgaa accttggagg ctattgagct tccattagat attctctatg aggatgacca
     9961 ctttctagtc ttgaataaac cctatggagt ggcttctatt cctagtgtca atcactctaa
    10021 taccattgcc aattttatca agggttacta tgtcaagcaa aattatgaaa atcagcaggt
    10081 tcacattgtt accagactag atagggacac ttctggcttg atgctctttg ccaagcacgg
    10141 ttatgcccat gcacgattag acaagcagtt gcagaagaaa tctatcgaga aacgctactt
    10201 tgctttggtt aagggagatg gacatttgga gccagaaggg gaaattattg ctccgattgc
    10261 gcgtgatgaa gactccatta ttaccagacg ggtggctaaa ggtggaaaat atgcccatac
    10321 ttcctacaag attgtagctt cttatggaaa tatccacttg gtcgacattc ggctgcacac
    10381 tggtcgaacc caccaaattc gagtccactt ttctcatatt ggttttcctt tgttgggcga
    10441 tgatttgtac ggtggtagtc tggacgacgg catccaacgt caggccctgc attgccatta
    10501 cctatccttt tatcatccat ttttagagca agatttgcag ttagaaagtc ccttgccgga
    10561 tgatttcagc aaccttatta cccagttatc aactaatact ctataaaaac tgtttcagag
    10621 tataattatt atcttaaagg agaaaactca tggaagtttt tgaaagtctc aaagccaacc
    10681 ttgttggtaa aaatgctcgt atcgttctcc ctgaagggga agagccacgt attcttcaag
    10741 cgactaaacg tttggtaaaa gaaacagaag tgattcctgt tttgcttgga aatcctgaaa
    10801 aaattaaaat ttatcttgaa attgaaggaa tcatggatgg ttatgaggtc atcgaccctc
    10861 aacattatcc tcaatttgaa gaaatggttt ctgccttggt ggagcgtcgc aagggcaaaa
    10921 tgactgaaga agatgtacgc aaggttttgg ttgaagatgt caactacttt ggtgtgatgt
    10981 tggtttactt gggcttggtt gatggaatgg tgtcaggagc gattcactca acagcttcaa
    11041 cagttcgtcc agctctacaa atcatcaaaa ctcgtccaaa tgtaactcgt acttcaggag
    11101 ccttcctcat ggttcgtggt acggaacgtt acctatttgg agactgtgcc attaacatca
    11161 atccagatgc agaagccttg gctgaaattg ccatcaactc agcaatcaca gctaagatgt
    11221 ttggcatcga acctaaaatt gccatgttga gctattctac taaaggttca gggtttggtg
    11281 aaagcgttga taaggtcgtt gaagcaacta aaattgctca cgacttgcgt cctgaccttg
    11341 aaatcgatgg tgagttgcaa tttgatgcag cctttgttcc tgaaactgca gctctgaaag
    11401 ctcctggaag tacggtagct ggtcaagcaa atgtcttcat cttcccaggt atcgaggcag
    11461 gaaatatcgg ttacaagatg gctgaacgcc tgggtggctt tgcggctgta ggacctgttt
    11521 tgcaaggttt aaacaagcca gttaatgatc tttctcgtgg atgtaatgca gatgatgttt
    11581 acaagttgac cctcatcaca gcagctcaag cagttcatca atagtgaaaa ctataaagcg
    11641 atatactatg ctatactgta gttatgaaac tatgtacgaa aagcactgcc attaattcct
    11701 gagaactaaa ttactgattg gtgtcaaaaa ggaaaacttc caagcgatga tattctgtct
    11761 atacacgacc tatagaaatc tgtaatatgt atgtccgtaa aacgataatt tccctttttg
    11821 attttaaatg agtatgaaaa gagaattttt catgagaaaa cgcataatat taagtgtctt
    11881 gacacctgct attatgcgtt ttttataatt tttgcacctt tcttagcctt tgttatcgac
    11941 aagtattgtt ctagctcctt gtttttagaa tggcaatttc ccagcgaaag cacccagttt
    12001 tttcttagta gtttcatcga tttgttcaag agcagagttg atggcttgaa cggtcgtatc
    12061 agaaagagtt tcaaggtcct ctgggtcaat gacagctgga ttgaaatcaa tgctgacaac
    12121 tttcttatct ccagttaagg tcgcttggac aagatcttga gcagatttgc caacaaattg
    12181 catagcagca agttcagctt ggctttgttc catttgtttt tgaagttttt gtgcttgacg
    12241 catcatgttt tgcatgttca tcataagatt tctaaagttc ctttcatctc aaggggataa
    12301 tccttgttgt taacaagtgc ctgattttct ctcctaattg ttattagtag catagccatc
    12361 aagcccaagt attgatttta ttataccatt tttttaagac atagtctttt attggtgaga
    12421 gttatttatg tcaaggagtg attagaaata aattaaaata atgatttttg ctaagagggc
    12481 tctattctag tttcatggaa atgattttac taaaggttcg tatgctttgt ttgcaaacat
    12541 gttacatcta tctatttttg gataaatagt tgtctattat tatttttatg ctaatagtaa
    12601 aatctaaatg gtagcctacg attttttaga aagaaaatgg tacaatattt ctaagagaaa
    12661 atacaatggg aggtaaaatg aggttattac ctataagaaa aatatcacgt cagtctaaaa
    12721 ggttagcact ttttttgacg ttttgtgctg gatatgtgga tgcttacact tttattgttc
    12781 gcgggaatac ccttgtagct ggacaaactg gaaatgttgt ctttctttca gtagaattaa
    12841 ttaaaaataa tgtttcggat gttagggaca aggttctcac cttgctagcg tttatgatgg
    12901 gagtcttttt attaacgatt tataaggaaa aattgagaat tgtgaaaaaa cctattctgt
    12961 ccttgattcc cttggcaatc ttatcaatca ttattggttt tgtgccgcaa actgtggata
    13021 atatctatct agtgccgccc ttggccttct gtatgggact ggtgacaact gcttttggag
    13081 aagtgtcggg tattgcctat aataacgctt ttatgacagg gaatatcaaa cggaccatgc
    13141 tggcttttgg agattatttc cgaaccaagc acactccttt tttgcgtgaa ggattcatat
    13201 ttgttagcct gcttagtagt tttgtccttg gcgttgtctt ttcagcctat ttgacgattt
    13261 tctatcatga aaagaccatt cttggtgttc ctattatgat gagcgttttt tacctcagca
    13321 tgctttttgc ctcttggcag aaaaaagtaa aagaaaaagc ttgattttag gtgttattac
    13381 ttgtaagaaa ataggagata tgctatactt gaagagttga ctatgcacga tcctgtgcaa
    13441 ccgcacgaac atcgttgctt gattattcaa gtttaagtgg ttcgtcccac gatgctaggc
    13501 gagtcttcac aaaaaatcgg ggaaacccat aaaaatcata ggaggtgcat aatgagcaca
    13561 tacgcaatta tcaaaactgg cggaaaacaa gttaaagttg aagttggtca agcagtttac
    13621 gttgaaaaat tgaacgttga agctggtcaa gaagttactt ttaacgaagt tgttcttgtt
    13681 ggtggtgaaa acactgttgt cggaactcca cttgttgctg gagctactgt agttggaact
    13741 gttgaaaaac aaggaaaaca aaagaaagtg gttacttaca agtacaaacc taaaaaaggt
    13801 agccaccgta aacaaggtca ccgtcaacca tatacaaaag ttgtcatcaa cgcaatcaac
    13861 gcttaatttt aaggagaaca catgatacag gcagtctttg agagagccga agatggcgag
    13921 ctgaggagtg cggaaattac tggacacgcc gagagtggcg aatacggctt agatgtcgtg
    13981 tgtgcatcgg tttctacgct tgccattaac tttatcaatt ctattgagaa atttgcaggc
    14041 tatgaaccaa tcctagaatt aaacgaagat gaaggtggct atctgatggt tgaaatacca
    14101 aaagatcttc cttcacacca gagagaaatg acccagttat tctttgaatc atttttctta
    14161 ggtatggcaa acttatcgga gaactattct gagttcgtcc aaaccagagt tatcacagaa
    14221 aactaacacg gaggaaaaca ttatgttaaa aatgactctt aacaacttgc aacttttcgc
    14281 ccacaaaaaa ggtggaggtt ctacatcaaa cggacgtgat tcacaagcaa aacgtcttgg
    14341 agctaaagca gctgacggac aaactgtaac aggtggatca atcctttacc gtcaacgtgg
    14401 tacacacatc tatccaggtg taaacgttgg tcgtggtgga gacgatactt tgttcgctaa
    14461 agttgaaggc gtagtacgct ttgaacgtaa aggacgcgat aaaaaacaag tttctgttta
    14521 cccaatcgct aaataaaaag gtccattgaa ccttttatcc cgaaccttga aatgtaaagg
    14581 tgaggaagct agaaacagct taaaataagg ctttccgagt tttcggagag cctgtttttt
    14641 tgttttggta cccatacttt ttaatatgta tagtggattg aatctggaat agaacactgt
    14701 taaaaattga tatgagtttc ctactcgatt tcttcagatt ttatttcaat tgactataag
    14761 aactgctatc tggtttcaaa tattggcttg tcgtcccttc acttgtctga atggtttgag
    14821 ccgttccttc tgataaggga aaagatattc tttagctgaa actgtctgag aatccaagct
    14881 aacagatgga gagaaaaata gcccagtctg aagcacacta aatgggagtt gttggaaagc
    14941 agtcatctag tttttctttg ctgttttggc ttttttcttt gtcatcaggg aaagtgactt
    15001 gcttcaaatc agggagttta ggaaattctt caaacatctt gcccaagttg tctcattttg
    15061 taaattttac agccataggt gtacctcgat tctaaattct accttttcgg caccaattag
    15121 taatttaaag ttctcaggag ttagttgcat tgctttttca tacataagca tagtatgaca
    15181 ctttatggtt accgaacaag tctaatcact ccttgcaaaa ttttgaagat gtcctacaag
    15241 tttttgagaa gaatattgca aagttcatag ttaagcaacg atagaataaa gtgctttttg
    15301 aaaacaggta cacttcatgt gaaaaaaaca acatttcaga ttttctgttc cagaaatagc
    15361 tatcgctatg atataattat tttatgatta ttactattcc tataaaaaac caaaaagata
    15421 ttggcacacc atctgattca gtcgttgttc tcggctattt tgatggcata cataaggggc
    15481 atcaagaatt atttcgtgtt gccaacaagg ctgcgagaaa ggatttatta cctatcgtcg
    15541 ttatgacctt taatgaatct ccaaagatcg ctttagagcc ttatcatcca gatttgtttt
    15601 tgcatatttt gaaccctgct gaacgtgaaa gaaaattaaa gcgcgaaggt gtagaagaat
    15661 tatatctcct tgattttagt agtcaattcg ctagtctcac tgcacaagaa ttctttgcaa
    15721 cttatatcaa ggctatgaat gccaaaatta ttgttgcagg ttttgattat acatttggtt
    15781 ctgacaaaaa aacagcagaa gatttaaagg attactttga tggagaagtt atcattgttc
    15841 cacctgtaga agatgagaaa ggaaagatta gttcaactcg tatccgtcaa gctattttag
    15901 atggaaatgt gaaagaagca ggaaaacttt tgggggcacc gcttccatca agaggtatgg
    15961 tggttcatgg taatgctcgt ggtcgtacaa ttggttatcc gacagcgaat ttagtgcttt
    16021 tagaccgtac ttatatgcca gcagatggcg tttatgtcgt tgatgttgag attcaaagac
    16081 agaagtatcg tgctatggct agtgtcggga aaaatgtgac ctttgatgga gaagaagcac
    16141 gttttgaagt caatattttt gattttaatc aagatattta tggggaaacc gtcatggttt
    16201 attggcttga tcgcattcgt gatatgacca aatttgactc agttgaccaa ttagtggatc
    16261 agttaaaggc tgatgaagaa gtaactcgga attggtctta agagcttgag taaataaaat
    16321 aaaaaagagg ttgtctgtaa cccaaaagat agatgattta gtctaacttt tgaggtcacg
    16381 acattacctc tttttattct ttttcaaagg tgaagccttc tcctaggatt tcatgggctt
    16441 ctgtaatagt tataaaggct tgaggatcga ttcgatgaat catttccttc gttttcacaa
    16501 tttcatttct tccgacaata cagtagatga ttttcaaatt ttctttacta tagtagcctt
    16561 gaccagaaat aaaagtaaca cctcttccga ggtcatcatt aatcgcctta gcaagttggt
    16621 caggacgttt tgtgataatc ataaagcctt tgccggcata tcctccttca ccaatcaaat
    16681 caataacacg agaaacaata aaatcaaaca aaagcgtgta ggaaaccaat ctcaaatcct
    16741 tgaagattag gagaatcaac atgagaatac aaaaatctaa gataaagagc agttttccta
    16801 tggatatatg agtgtatttg ttgagaatac gagctagaat atcagttccg ccagttgtac
    16861 ctccagcatt aaaaataatt ccaaggccaa ttcccaatag gattcccgct ataagggctg
    16921 tgattagtaa atcaccttga agatcaatat gaaggggaat atgctcaaaa aaagctaacc
    16981 agccggacaa agctaaggtt cctagtaaac tagaatagag ggatttggct ccaaaaatct
    17041 tccaagctag gatgaaaagg ggaatattaa tcagcaggtt catgagggaa acagggattt
    17101 taaaaagata aaaggtgatg agggtaatgc ctgtcgcccc tccttcaaag agatgatggg
    17161 gaactacaaa ataagtcagt ccaaaagcat aaatagcagc acctagtaaa atggtaaaaa
    17221 tggggtaaat ttttttaatc ataggacacc tcttttctta taagttgatt atatcaaat
//
LOCUS       DAVLTT010000042        16078 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLTT010000042 DAVLTT010000000
VERSION     DAVLTT010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16078
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.042"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            12..965
                     /locus_tag="VYN15_001494"
     CDS             12..965
                     /locus_tag="VYN15_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1452798.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            1042..3030
                     /gene="uvrB"
                     /locus_tag="VYN15_001495"
     CDS             1042..3030
                     /gene="uvrB"
                     /locus_tag="VYN15_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV1452799.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDVNSLNKQE
                     RKDLVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            3040..3603
                     /locus_tag="VYN15_001496"
     CDS             3040..3603
                     /locus_tag="VYN15_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1452800.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            3569..4057
                     /locus_tag="VYN15_001497"
     CDS             3569..4057
                     /locus_tag="VYN15_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1452801.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            4131..4598
                     /locus_tag="VYN15_001498"
     CDS             4131..4598
                     /locus_tag="VYN15_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1452802.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(4595..5110)
                     /locus_tag="VYN15_001499"
     CDS             complement(4595..5110)
                     /locus_tag="VYN15_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV1452803.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQRLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(5122..5649)
                     /locus_tag="VYN15_001500"
     CDS             complement(5122..5649)
                     /locus_tag="VYN15_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1452804.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(5931..6494)
                     /locus_tag="VYN15_001501"
     CDS             complement(5931..6494)
                     /locus_tag="VYN15_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1452805.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(6478..7029)
                     /gene="coaC"
                     /locus_tag="VYN15_001502"
     CDS             complement(6478..7029)
                     /gene="coaC"
                     /locus_tag="VYN15_001502"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV1452806.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(7041..7730)
                     /gene="coaB"
                     /locus_tag="VYN15_001503"
     CDS             complement(7041..7730)
                     /gene="coaB"
                     /locus_tag="VYN15_001503"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV1452807.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGYEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISTDQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            7960..9630
                     /locus_tag="VYN15_001504"
     CDS             7960..9630
                     /locus_tag="VYN15_001504"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV1452808.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDTIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            9958..11133
                     /gene="mutY"
                     /locus_tag="VYN15_001505"
     CDS             9958..11133
                     /gene="mutY"
                     /locus_tag="VYN15_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV1452809.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            11188..11892
                     /locus_tag="VYN15_001506"
     CDS             11188..11892
                     /locus_tag="VYN15_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1452810.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            11885..13234
                     /gene="vicK"
                     /locus_tag="VYN15_001507"
     CDS             11885..13234
                     /gene="vicK"
                     /locus_tag="VYN15_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV1452811.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            13236..14045
                     /locus_tag="VYN15_001508"
     CDS             13236..14045
                     /locus_tag="VYN15_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1452812.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            14136..14378
                     /locus_tag="VYN15_001509"
     CDS             14136..14378
                     /locus_tag="VYN15_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV1452813.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            14380..14634
                     /locus_tag="VYN15_001510"
     CDS             14380..14634
                     /locus_tag="VYN15_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1452814.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            14709..>16078
                     /locus_tag="VYN15_001511"
     CDS             14709..>16078
                     /locus_tag="VYN15_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000150981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEV1452815.1"
                     /translation="MTIDISEESLAKESADLLKILLKDRTTKKSIVWATHSYELLGKG
                     FAPSDRINPSKVTGNFANLIQPRSEKSKYEQKDRTKIRAEVFTPTWLVAKQNGYVESK
                     LGSLSLEEYVDLRWLEVTCGEAPYMVTRYDTVTGEEIPLSERVGFVDRKLQRISREVS
                     DEVTFYKLVKDAYHASYGYEYQGDSLLLARENLLATFEDYYLAKTGNQPTLEKKKEIA
                     TIISYNVFQMDGLKKSSPYSAKQKQSQQLSLFADELEVQEVEESKTHIKDWKKNRMIG
                     FERLSSEESEMKFDVVIGNPPYQETGEARDEPIYHYFIDEAYKIADKSILITPARFLF
                     KAGQTPKNWMEKMLEDKHLKVQFYELKSGKVFTGTDIKGGVAITYRDVDKDLGPIGVF
                     TIFETLNGIVKKIEKHPEFETFSDLVYPQGIYRFSNKLFSDYPNAEKLQGKGTKNKIV
                     SKSLTQ"
BASE COUNT         4943 a         2787 c         3588 g         4760 t
ORIGIN      
        1 aggacgggga tatgaagaac aaaagaatat ttaaagactt ccaagcttca aaaatgagtt
       61 taaacattta cacaagcccc ttgttagcct ttgtttttgt cttcatagga gagtttgtgg
      121 cttatacttt atatggtatt agtttgttag ctctcatcgg acttgctaga aattttggag
      181 aggctggtca aaatcttgca agctacttgc agaccttgca tcagagcttg acggataaaa
      241 caagtgactt tcgtttaatt ttaggattac tggcctttgg ttttattctt aacactgtgt
      301 tcagatggac aagaaaagtt gagaaaagac ctattcgaac cttgggattt tatagagaga
      361 atttcctcag caatcttctg aaaggattta gtctaggcct ggcacttttt cttctgacct
      421 tgttaggttt agtagtctta ggtcaatatc gtttggaatc cattcacttg aatccttatt
      481 ctcttgcctt tgtcgtcttt actatcccat tttggatttt acaggggaca gcagaagaag
      541 tggtggcccg tgcttggcta cttcctcaat tggcctcaag aaccaatcta aaactagcta
      601 ttcttatatc tagcctgttc tttaccctgc ttcatatggg caattctggt ctcacccctc
      661 tatctctagt aaatctcttt ttattcggag ttgccatggc tctttacctt ctcaaaactg
      721 atacagtttg gggtgttgca ggtattcatg gtgcttggaa ttttgctcag ggtaatctct
      781 ttgggatttt agttagtggt caaccgtcag gaacgtctct gatgaccttt ttaccacaag
      841 gcaatcaaga ttggctatca ggtggttctt ttggcataga aggttccatt atgacaagtc
      901 tggtattact actgctgatt gtctatcttg ctaataaatt aaagaaagaa aatgaaagga
      961 tgtgacttcg gtccatcctt ttcttcgtga aaatactata agtatgctaa aataggaata
     1021 gcacatggag agaggattct tatgatcaat cacattacag ataatcaatt taaactagta
     1081 tcaaaatatc aaccatcagg agatcaaccc caagctatcg agcagttggt ggataacatt
     1141 gaggggggag aaaaagcaca gattctgatg ggggcgactg gaacagggaa gacctatact
     1201 atgagtcagg tcatttctaa agtcaataaa ccaactctgg ttattgccca caataaaact
     1261 ctggctggtc agctctatgg ggagtttaag gaatttttcc ctgaaaatgc agttgagtat
     1321 ttcgtatcct actatgatta ttaccagcca gaggcctatg tcccttctag cgatacctat
     1381 attgagaagg atagttctgt caatgacgag attgacaagc ttcgccactc agctacctca
     1441 gcccttttgg agcgtaatga tgttattgtc gtggcctcag tctcttgtat ctatggtttg
     1501 ggttcgccca aggaatacgc tgatagtgtc gttagtctcc gtcctggtct agagatttct
     1561 cgtgataaac tcttgaatga cttggtcgat attcagtttg aacgcaatga tattgatttc
     1621 caacgcggaa gatttcgcgt tcgtggggat gtggtagaga ttttcccagc ttcccgagat
     1681 gaacatgcct ttcgagtaga attttttgga gacgaaattg accgtattcg tgaagttgag
     1741 gctctgacag gtcaggtgtt gggagaagtg gatcatttag cgattttccc agcgacacac
     1801 tttgtgacca atgacgacca catggaagtt gccattgcaa agattcaggc cgagttggaa
     1861 gaacaattag ctgtctttga aaaggaaggt aaactgcttg aagcccagcg tttgaaacag
     1921 cggacagagt atgatatcga aatgttgcgt gagatgggct ataccaacgg ggttgagaac
     1981 tattcacgac acatggatgg acggagcgaa ggagagcctc cttatacgct cttagatttc
     2041 ttcccagatg attttttaat tatgattgac gagagtcaca tgaccatggg gcaaatcaag
     2101 ggcatgtaca atggagaccg ttcgcgtaag gaaatgctag taaattatgg tttccgttta
     2161 ccgtctgcct tggacaatcg tcctctccgt cgtgaggagt ttgaaagcca tgtgcatcag
     2221 attgtttacg tatcagcgac acctggtgac tatgaaaatg aacagactga gacggtgatt
     2281 gagcaaatca ttcgaccgac agggcttttg gatcctgagg tggaagtccg tccgactatg
     2341 ggacagattg atgatctctt aggtgaaatc aatgcccgtg ttgaaaagaa tgaacgaacc
     2401 tttatcacca ccttgaccaa gaaaatggca gaggacttga ccgactactt caaggaaatg
     2461 ggtatcaagg ttaagtacat gcactcggat atcaagacct tggaacggac ggagattatc
     2521 cgtgacctgc gcttgggtgt ctttgatgtc ttggtcggaa ttaacctgct ccgtgaagga
     2581 attgacgttc ctgaagtgag cctcgtagct attctcgatg ctgacaagga aggtttcctt
     2641 cgcaacgaac gtggactcat ccagactatt ggacgtgctg ctcgtaacag tgaaggccat
     2701 gtcatcatgt atgcagacac ggttacccag tctatgcaac gtgctatcga tgaaactgcc
     2761 cgccgtcgga aaattcagat ggcctataat gaagaacatg gtatcgttcc acaaaccatt
     2821 aagaaagaaa tccgtgacct gattgccgta actaaggcag ttgctaagga agaagacaag
     2881 gaagttgatg ttaatagcct caacaaacaa gaacgtaaag atcttgttaa gaaactcgaa
     2941 aaacaaatgc aagaagccgt cgaagtgctt gactttgaac tagcagcaca gattcgtgat
     3001 atgatgttgg aagtcaaggc gttggattag gggaatagta tgatttattt aagaaagtta
     3061 aagagagaag atttgatgtc tttatgggaa atggcttatt cacaacttaa tccagtttgg
     3121 aaacagtatg atgctcccta ttatgatgat tatcagtatt tttcaaattt taaagaattc
     3181 gaactacaaa aatcagaatc cattttaagc aactcaaatc gccttggtat ttttgttgat
     3241 gataaactag ttgggactgt ttcgcgttat tgggtatgta aacaaacaag atggatggaa
     3301 ttgggaattg gtatttatga taaaaaattc tggaacactg gtattgggaa agttgctatg
     3361 ttgcagtgga tagataggac gtttcaggat tacttggagt tggagcatct gggtttgaca
     3421 acttggtcag ggaatcttgg tatgatgaaa cttgctgaaa aattaagaat gaaaaaagaa
     3481 gctcatattc caaaagttcg ttattatcaa ggtaaatatt ttgatagtat taaatatggt
     3541 attttgagag aagactggga gaaaataaat gacggttatt atcaaatcaa tggaaactcc
     3601 tgaagagata gaaggtaaat ccctcgttca ctggcaaacg tggagagagg cttatgatga
     3661 ccttttgcct gcggaatttc aggatacaat gacattagaa agatgtcgat tctttagtca
     3721 aaagtatcca gaaaatacat tgattgcgat ggatggcgtg aaggtggttg gttttatcag
     3781 ttatggcaat tttcgtgatg agactattca agctggtgaa attattgctt tatatgtttt
     3841 aaaagactat tatggaaaag gtatcgcaca aaagttaatg aaagcagctt tgactgctct
     3901 taatcatttt tctgaaattt tcttatgggt attgaaagat aacaagcgcg ccattgcttt
     3961 ctatcaaaaa atgggtttta cttttgatgg acaagaaaaa atacttgaac ttggaaagcc
     4021 tataaaggaa aaacgaatgg tgttctattc taaataattt taaaaaagta aaagataata
     4081 tctctggtag taagtctgaa aatttaataa attagaaagc gagtaaattt atgtcccgtt
     4141 cccaattaac aattttaaca aatatctgtc tgattgaaga cctcgaaact cagcgcgtgg
     4201 tgatgcagta tcgcgcccct gaaaacaatc gctggtctgg ttatgccttt cctggaggtc
     4261 atgtagaaaa tgatgaggct tttgcggagt ctgtcattcg tgaaatctac gaagaaacag
     4321 ggttgactat ccaaaatcct caacttgtcg gcattaaaaa ttggccacta gatacaggtg
     4381 ggcgctatat tgtcatttgt tataaggcga ctgagttctc tggtaccctt caatcttcag
     4441 aagagggaga agtttcttgg gtgcaaaaag accagattcc aaacttaaat ctggcctatg
     4501 atatgctacc attgatggaa atgatggaag ctcccgacaa gtcagagttt ttctaccctc
     4561 gccgtacaga agacgattgg gaaaagaaaa tcttctagtc ttttactaaa taacctagct
     4621 gatccaaggc ctcctcgata tagtggaggt cttgttgtgt ttcggcttcg actaggtggt
     4681 aatggatgcc atctgtcaat tcagatagag gtctaaagtc agaatgctcg acttgttcta
     4741 gaaaatgttg cacatctctg cgacaagaca gtttaagcaa ggtttcaatt tctccataaa
     4801 cgggatggtc aatcaaggta ttctggacat gcccaccatt atcgacaata gcaaggagtt
     4861 cctgaccgat ttcttcaact tcatgtttca ctttgaaaag tttgtgaaca taaggattgg
     4921 tatcaatttg cttatagata taaccacgat tggtagatag aattggagct ccatcagctc
     4981 ttaaaattgc aatatcttga acaataactt gtcgagtgac atgaaagtgc tcagctaatc
     5041 tttggccatt gagggcttta ggagcttctt tcaagagttg gagcagggct tgtttgcgat
     5101 cttttgtcat agttcttcct tttaacggcg ttttcgaagc actttataga cagctagtgc
     5161 taatgtatag tctaccatac tatggataat tgtgccaaat ccaactagta caaatagaac
     5221 atagaacata ttttctacat tggtacccga agttgcgtaa aaaaggacac aggctaatac
     5281 ttcagcaagg gcatgaacaa cagccaaaac aaaattgaaa acccaggaag attttggttt
     5341 atctagggta tcggggaatt tttgtaggta aagagctcct aaagcaccaa aagatatatg
     5401 ggaaaaagcc cgaaaaacga taaccatggg atagccagcc atcaaaaatc caaaactaga
     5461 ggctaggatg acaaaaactg ccatcaaggg cgacaagaac atggctataa aaatagcgat
     5521 gtggctcccc aaagtatagg aagcaggtgg aatgacaatc ttgaaaggca taacaattgg
     5581 aatcaaaatc gcaatagccg ttaaaagggc tgtcattgtc ataaattgtg tctttttccg
     5641 tgtattcaca agaatctcct ttttaactgc atatacacta gtatggtaca ataaaccaga
     5701 caataaagca agaatttact tgggtttata gatcattttt tagttaaaag ttatagtaga
     5761 tggaaactag aatagtccac ctctacttct aaaacattgt tagaaatcga tttgactgtc
     5821 ctgatcgatt tgtcctgttc ttatttcgtt ttactatagt aaagatttca ttaaaaagaa
     5881 actgtataga gcaaaatctc caccttcagg tttgaaagcg gagattgttt ttattttttc
     5941 aaggtttgta gtcgtggaac aatggctagg gttagaattg cagaaatgac caattcagca
     6001 attgaatttg ttgagataac ggttgccaga agaagttgga tatttccatt ataaacattt
     6061 ccaaatagga agaagattcc tccaaggaca aagatagtat ttgtcaagga accaagggct
     6121 ccagctaaaa tcagaccagt cttgtttttc atcagtttat agactaagta aggagttaaa
     6181 ccaatcaaaa tacgtgggac gatggcaatg atagctgagt agatgtttcc gtttggtacg
     6241 aagggagaga agaggtagct tgtcggtaga atcgtaatcg tgttaaccgt caagctaagt
     6301 aatcccatca aaaatccaag tgtaacccca actcgtggac cataaataat gctggcaata
     6361 atgacaggaa tatgaacaat ggtcggtttg attggaaatg gaaaaaggtt aaagataagt
     6421 gagctcagaa agtgtatcac gagcatggta gcaaaaaaga tagcaatggg tgcaatatta
     6481 gagcgttttt tcatcgatag tttcctttat tctttctaaa ataattgtga ggtcagctaa
     6541 agctcctcgt ccgtggtctc cacaagctag tagggattcc ttaggagcaa tcagctgata
     6601 gccgtaggtt tctaatgttt tcagattatt ctgagttact ggatggtcat acatttttgt
     6661 attcatagca ggagctatta gtttgggaat atgacttggt agggctagag ctgtactggt
     6721 taccatgttg tccgcaaatc cgtgagctag ttttgcaata gtgttagcag ttgcaggtac
     6781 cacgataaat aaatctgctt tttttccaag ttcgatatga ttgacctgat caggataggg
     6841 ttccttcatg acatccaagt ggacaggatt ctgtgagagt acctgtagtg tcaaaggttg
     6901 gataaactct gtagcagcct gagtcattaa gacagtgact tgatggcctt gtttttttag
     6961 agaactgact aaatctgccg acttataaga ggcgattgaa cccgttacag ccaagagaat
     7021 gtttgccata gttttccttt ctaagaatga taggcttgaa ttttttcaag gaggagttct
     7081 gcaatttctt ctttagtctg gactgtttga agctgatttt tctcaacaaa tatagctcgg
     7141 tgctgatctg ttgaaatttg agtcaggtca ttcgcgatga ttaaatctgc ttgattcttg
     7201 ataagacttt ttcgtgcaat gtcaaccaga tgatcttcgg taacatcaac cagcagtttg
     7261 aaaccaatca gatgaatagt aggattccat tccttgacta gggatatgat tttgggtgtc
     7321 tttttaagga acaaaacctg aacctcatca gttgaagaaa tcttggcctg atgattttgc
     7381 ttgcttaaaa attcttttag attggagcta gcctgaactt cctcaagccc tgtcatataa
     7441 acaggagtgt agtcagaaac agccattgag tggatcaaga cctgataatc ctgaacacgt
     7501 tcttgcattt ctattagaag gtccttggta ttggtaattt ctcgaatact taggttagga
     7561 tgaggctctg gcttcagagc tcgttttgtc gtaattaaac aaacttcata ccctgcagaa
     7621 agcaaagtct ctgtgataat tttccccaag tgacctgtag aatggttagt gatagagcgg
     7681 acgctatcga tagcttcact ggtaccgccc gatgtaacta aaattttcat agcactattg
     7741 tacacaaaaa taagcggtaa gtaaaatgaa agtgataaat ttttggtaaa aacgaagatt
     7801 tattatagtt tcaaactata aagccatata aaatttaaga aaggactcta aaagtcttaa
     7861 aaacagagat atttacgaac gtttagagag ttttaggatg ttaaaaatct tgttttgtga
     7921 tataatgaat tatcatataa gaggttagag gaattttgaa tgaaaacaga tattgaaatc
     7981 gcacagagta ttgagttgaa gccaattgtt gatgttgtag agaaacttgg tatttcttat
     8041 gacgatttgg agttgtacgg aaagtacaag gctaaactca gctttgataa aattcgtgca
     8101 gttgagagca atccagtcgg taaattgatc ttggttactg ccatcaaccc aacacctgca
     8161 ggtgaaggaa agtcgacgct taccattggt cttgcggatg ccttgaacaa gattggcaag
     8221 aaaaccatga ttgctatccg cgaaccgtct cttggtccag tcatggggat caagggtggt
     8281 gctgctggtg gtgggtatgc acaagttctg ccaatggaag acatcaacct ccactttact
     8341 ggagatatgc atgctattac aactgccaac aatgcccttt ctgccttgat tgacaaccac
     8401 ttgcaccaag ggaatgagct ggaaattgat caacgtcgta tcctctggaa acgcgttgtg
     8461 gacttgaacg accgtgcgct ccgccatgtg actgttggtc ttggtggtcc tctaaacggt
     8521 attccacgtg aggatggttt tgatattaca gttgcttcag aaatcatggc aattctttgc
     8581 ttggcaacgg acatcgagga cttgaaacgt cgtttggcga atatcgttat tggttatcgc
     8641 tatgaccgta cgcctgtttc tgtaggtgat ttgcaggttg agggtgcctt ggctttgatt
     8701 ttgaaggata ctattaagcc aaacttggtt cagacaattt acggtacacc tgcctttgta
     8761 cacggtggtc catttgccaa tatcgctcat ggctgtaact ctgttttggc gacgacaaca
     8821 gcccttcact tggctgatta cactgttact gaagctggtt ttggtgcgga ccttggtgct
     8881 gagaaattcc ttgatatcaa gacaccaaac ttgccaacat ctccagatgc agttgttatt
     8941 gtcgcaaccc ttcgtgccct taagatgaat ggtggtgtgg ctaaagacgc tctgactgaa
     9001 gaaaatgtag aggcagttcg tgcaggtttt gctaacttga aacgtcacgt tgaaaatatc
     9061 cgtaagttcg gtattccagc agttgtagct attaacgaat ttgtatctga tacagaagct
     9121 gaaattgcag ccttaaaaga actctgtgcc tcaatcgatg taccagttga attggctagt
     9181 gtctgggctg atggagcaga aggtggagta gcacttgccg aaacagttgt taagacaatt
     9241 gctgaaaatc cagctaacta taaacgtttg tacgataatg acctttctgt ccaagaaaag
     9301 attgaaaaaa ttgtcactga aatctatcgt ggtagcaaag tgaactttga gaagaaagct
     9361 caaacacaaa ttgctcaaat cgttcaaaac ggttgggaca aattgccaat ttgtatggct
     9421 aaaactcaat acagtttctc agacaatcca aatgcgcttg gagcaccaga aaactttgaa
     9481 attaccattc gtgaattggt accaaaatta ggtgcaggct tcatcgttgc cttaactggt
     9541 gatgttatga ccatgccagg tcttccaaaa cgtccagcag ctctcaacat ggatgttgaa
     9601 agcgatggaa ctgtactagg cttgttctag tggattgaaa ttgactttaa gtgagtttgg
     9661 aaataatatc caagctcatt ttttctcaga ctgcaagcag ttcatcaata agatttatac
     9721 tcttcgaaaa tcttttcaaa ctacgtcagc ttcaccttgc cgtaggtata tgatactgac
     9781 tctgtcagtt ctatccacaa cctcaaaaca gtgttttgag caacctgcgg ctagcttcct
     9841 agtttgctct ttgattttca ttgagtataa gtagatagaa aagttatata ctatctattg
     9901 aaaatattat aaatcagata caaagacagg tgaaaccttc tgtgttatac tagagatatg
     9961 ttagatttga aagaatacgg tatcgtcatg tggccggagg agaaagtcat ttctttccgt
    10021 gagaaacttc tcgcttggta tgatgaaaac aaaagagatt tgccttggag gagaagtaaa
    10081 aatccttatc acatctgggt atctgaaatc atgcttcagc agaccagggt ggatacagtt
    10141 atcccttact acgaaagatt tttggactgg tttccaactg tcgaaagtct ggcaactgcg
    10201 cctgaggaga gtttactgaa agcttgggag ggcttgggct attattctcg agttcgcaat
    10261 atgcaggctg cagcccagca gattatgact gactttggtg gccaatttcc aaatacctat
    10321 gaaggaattt ccagcttgaa agggattgga ccttacacag caggagccat ttccagtatt
    10381 gcttttaact tgcctgagcc agctgtagat ggtaatgtca tgcgggtctt ggcgcgtctg
    10441 tttgaagtca accacgatat tgggattcca agtaatcgaa aaatttttca ggcaatgatg
    10501 gagatcttga ttaatccaga tcgtccgggt gattttaatc aagccttgat ggacttaggg
    10561 tctgatattg agtctcctgt aaatcccaga cctgaagaaa gcccagtcaa ggactttagt
    10621 gcggcatatc agaatggaac catggaccgt tatccaatta aatctcctaa gaaaaagccg
    10681 gttcctattt atcttaaagc cttagttgtg aaaaattctc aaggacaatt tttacttgaa
    10741 aaaaatgaaa gcgaaaagct cttggcaggt ttttggcatt tcccctttat agaagttgat
    10801 aacttttcgc aagaagagca gtttgacctc tttcatcagg ttgcggaaga aagtgtgaac
    10861 tctggcccca gtccagaaga gagtttccag caggactatg acctagatgt tgattggctt
    10921 gatgtttgtt ttgatacagt ccagcatgtt tttagtcatc gaaaatggca tgtacagatt
    10981 gtagcaggtc aggtgagtga cttccatgat ttttcagata gggaagttcg ttggctttca
    11041 ccagaagaat tcaagaatta cccacttgcc aaaccccaac aaaaaatctg gcaggcttat
    11101 gcacaagcca acttagacag tagccaagac tagctattgt gtcttctgac tattttttgg
    11161 tataatagta gagaaaaagg tgaacatatg aaaaaaatac taattgtaga tgatgagaaa
    11221 ccaatctcgg atattatcaa gtttaatatg accaaggaag gttacgaagt tgtaactgct
    11281 tttaatggtc gtgaagcgct agagcaattt gaagcagagc aaccagatat tattattctg
    11341 gatttgatgc ttccagaaat tgatggttta gaagttgcta agaccattcg taagacaagc
    11401 agtgtgccca ttcttatgct ttcagccaaa gatagtgaat ttgataaggt tatcggtttg
    11461 gaacttgggg cagatgacta tgtaacgaaa cccttctcca atcgtgagtt gcaggcacgt
    11521 gttaaagctc ttctgcgtcg ttctcaacct atgccagtag atgggcagga agcagatagt
    11581 aaacctcaac ctatccaaat tggggattta gaaattgttc cagacgccta cgtggctaaa
    11641 aaatatggcg aagaactaga cttaacccat cgtgaatttg agcttttgta tcatttagca
    11701 tcgcatacag gtcaagtcat cacgcgcgaa cacttgcttg agactgtctg gggttatgac
    11761 tattttggtg atgtccgtac agttgatgtg actgtacgac gtctgcgtga gaagattgaa
    11821 gatacgccca gccgaccaga gtatatcttg acgcgccgtg gtgtagggta ttacatgaga
    11881 aataatgctt gatttactga aacaaaccat ttttaccaga gattttatct ttatcctgat
    11941 tttgttaggt ttcatccttg ttgtgaccct cttattactg gaaaatagac gtgataatat
    12001 tcagttgaag caaatcaatc aaaaggttaa agatttgatt gcaggagatt attccaaggt
    12061 tcttgatatg caaggtgggt ctgaaatcac taatattacc aataatttga atgacttgtc
    12121 ggaggttatt cgtctcactc aggaaaatct agaacaagag agtaagaggc taaatagtat
    12181 tctgttttat atgacagatg gggttcttgc gaccaaccgt cggggtcaga ttatcatgat
    12241 taacgataca gccaagaagc aactggggtt ggttaaggaa gatgttctga atagaagcat
    12301 tttggaattg ctcaagatag aagaaaacta tgaattgcgt gatttgatta cccaaagtcc
    12361 agaattgttg ctagattccc aagatatcaa tggcgaatat ttgaaccttc gagttcgctt
    12421 tgccttgata cgtcgagagt ctggctttat ttcaggtttg gtggctgttt tgcatgatac
    12481 gacggagcag gagaaggaag aacgcgaacg aagactcttt gtttccaatg ttagccatga
    12541 gttacggact cctctgacta gcgtaaaatc ctatcttgaa gccttggatg agggggcttt
    12601 gtgtgaaact gtagcaccag actttatcaa ggtttctctt gatgaaacca accgtatgat
    12661 gcgcatggtg acggatctcc tccatctttc acgtattgat aatgctacca gtcacctaga
    12721 tgtggaactg attaacttca ctgcttttat tacctttatc ctcaatcgtt ttgacaagat
    12781 gaaaggacag gaaaaggaga aaaaatatga gttggtgaga gattatccca tcaattctat
    12841 ctggatggaa attgatacag ataagatgac gcaggttgtc gacaatattt taaataatgc
    12901 tattaagtat tcgccagatg ggggtaaaat cactgtcaga atgaagacaa ctgaagacca
    12961 gatgatttta tccatttctg accacggttt ggggattcct aagcaggatt taccacgtat
    13021 ctttgaccgt ttctatcgtg tggatcgtgc tagaagtcgt gcacaaggtg gtacaggtct
    13081 aggactgtct atcgctaaag aaattatcaa acaacataag ggctttattt gggccaagag
    13141 tgaatacggc aagggttcaa cctttaccat tgtgctccct tatgataagg atgcagtgaa
    13201 agaagaagta tgggaggatg aagtagaaga ctagaatgag tgaaataggc tttaaataca
    13261 gtattttagc gtcgggttcc agtggaaatt ctttttatct ggaaacctca aaaaagaagc
    13321 ttttagtaga tgcaggcttg tctggcaaga aaattaccag tctgctagct gaaattaacc
    13381 gtaagccaga agacctggat gccatcttga ttacccatga gcattcagat catatccatg
    13441 gagtaggcgt tttggctcgc aagtatggta tggatcttta tgccaatgaa aagacctggc
    13501 aagctatgga aaatagtaaa tatcttggca aggtggattc ttcgcaaaag catatttttg
    13561 aaatgggtaa aaccaaaacc tttggagata tcgacatcga gagttttggt gtaagccatg
    13621 atgcagtcgc accgcagttc tatcgcttta tgaaggatga taagagtttt gtcctcttga
    13681 cagatacagg ttatgtcagt gaccgtatgg cgggcattgt cgaaaatgcg gacggttatc
    13741 ttatcgaggc caaccatgat gtagagattt tgcgatcagg ttcttacgct tggcgcctca
    13801 aacaacgaat cctatctgac cttggtcacc tttctaacga ggacggtgct gaagctatga
    13861 ttcggacgct aggaaatcgt actaagaaga tttaccttgg gcatttatct aaggaaaata
    13921 atatcaagga actggctcat atgaccatgg tcaatcagct ggctcaagct gatctgggag
    13981 tcggagtaga ctttaaggtt tatgatacct caccagatac cgcaacacca ttgacagaga
    14041 tatagaaaga acgctgagaa ggtgttcttt ttatattgac tggacaccta aaaagtaata
    14101 caatggtgtt accattaaaa aagggagcac aaaagatgac tactattaca ttaaaagttt
    14161 ctgaagctga taaaacattt atgaaagcaa tggctaagtt tgaaggagtt tccctttcgg
    14221 aacttattcg caccaaaact cttgaagccc tagaagatga atacgatgct cgtgtggcag
    14281 atttagccta tcaagagtat ttagaagact tggaaaaagg agttgaaccc attacttggg
    14341 aagaaatgat gcatgattta ggcttgaagg atgaataatt tgtataaatt agttccaaca
    14401 agacgtttta tcaagcaatt gaaaaaattg gaccgttata cgcagaagct aattacaaac
    14461 tatttacaaa ccaatgtttt ggaagatcca agacgacacg gaaaggcttt ggttggtaat
    14521 cgcgttggtc aatggcgcta tagaattggt aattatcgag ttatcgtaca aattgtagat
    14581 gatgaattag ttgttgctac tctagaagtt ggtcatcgga gagatattta ttgaattact
    14641 tttttcaagt aaattttcat tctttaaaat atgatataat agggcttaca atataagaga
    14701 ggttgctgat gacaatagat attagtgaag aaagtttggc taaagaatcg gctgacttat
    14761 taaaaattct tttaaaagat cgaacgacaa agaaatcaat tgtttgggct acgcattctt
    14821 atgaattgtt aggaaaggga tttgctccaa gtgatcgcat caatccaagt aaggttactg
    14881 gaaactttgc caacttgatt cagcccagat ctgaaaaatc caaatatgaa caaaaagatc
    14941 ggacaaaaat aagggcagaa gtgtttacac caacgtggtt ggtcgcaaag caaaatggat
    15001 atgtagaatc gaaattaggc tcgttaagtc ttgaggagta tgtggactta cgatggttag
    15061 aggtaacttg tggtgaagca ccttatatgg taacgagata tgataccgta actggtgagg
    15121 aaattccatt atctgagcga gttggttttg ttgatagaaa actgcaacgg attagtcgtg
    15181 aggtttcaga tgaagtcaca ttttataaac ttgtaaaaga tgcttatcat gcttcgtatg
    15241 gttatgagta tcaaggagat tctctccttt tggcgcgtga gaatcttttg gcaacttttg
    15301 aggactatta tctagctaag actggaaatc aaccaacatt agagaaaaag aaagaaattg
    15361 cgactattat ctcttacaat gtctttcaga tggatggatt gaaaaaaagt agtccttatt
    15421 cagctaaaca aaagcaatct caacaattga gtttgtttgc ggatgagcta gaagtccaag
    15481 aagtagaaga atctaaaacc catatcaaag actggaaaaa gaatagaatg ataggttttg
    15541 agcgcctatc tagcgaggaa agtgaaatga aatttgatgt cgtgatagga aatccgccgt
    15601 atcaggaaac aggagaagcc agagatgagc cgatatatca ctattttatt gatgaagctt
    15661 ataaaatcgc agataaatct atactaatca ccccagcaag gtttttattt aaagctggtc
    15721 aaactcctaa aaattggatg gaaaagatgc ttgaagacaa gcatttaaaa gttcaattct
    15781 atgaacttaa aagcggtaaa gtatttacag gaacggatat taagggtgga gtagcaataa
    15841 cttatcgtga tgttgataaa gatttgggac caatcggagt atttactatt tttgaaactt
    15901 tgaatggtat tgtaaaaaaa atcgaaaaac atccagaatt tgaaactttt tctgatttag
    15961 tttatcctca aggtatttat agattttcaa ataaactttt ttctgattat ccaaatgctg
    16021 aaaagctgca aggaaaaggg acaaaaaata aaattgtttc gaaatcacta actcagtt
//
LOCUS       DAVLTT010000043        15688 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLTT010000043 DAVLTT010000000
VERSION     DAVLTT010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15688
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.043"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            98..2155
                     /gene="pbp2b"
                     /locus_tag="VYN15_001512"
     CDS             98..2155
                     /gene="pbp2b"
                     /locus_tag="VYN15_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV1452816.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            2166..2762
                     /gene="recR"
                     /locus_tag="VYN15_001513"
     CDS             2166..2762
                     /gene="recR"
                     /locus_tag="VYN15_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV1452817.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            2938..3981
                     /locus_tag="VYN15_001514"
     CDS             2938..3981
                     /locus_tag="VYN15_001514"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV1452818.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            4065..5438
                     /locus_tag="VYN15_001515"
     CDS             4065..5438
                     /locus_tag="VYN15_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV1452819.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIERAFENGAAATLSEKEVANHPYILVDDVLTAFQQLAAYYLEKTAVDV
                     FAVTGSNGKTTTKDMLAHLLSTTYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASNSLLLAP
                     ADSIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLVSQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     RLENEVK"
     gene            5533..6237
                     /locus_tag="VYN15_001516"
     CDS             5533..6237
                     /locus_tag="VYN15_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV1452820.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            6456..7829
                     /gene="ftsA"
                     /locus_tag="VYN15_001517"
     CDS             6456..7829
                     /gene="ftsA"
                     /locus_tag="VYN15_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV1452821.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFASQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            7846..9105
                     /gene="ftsZ"
                     /locus_tag="VYN15_001518"
     CDS             7846..9105
                     /gene="ftsZ"
                     /locus_tag="VYN15_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV1452822.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            9110..9781
                     /locus_tag="VYN15_001519"
     CDS             9110..9781
                     /locus_tag="VYN15_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV1452823.1"
                     /translation="MNVKENTELVFREVAEASLSANRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            9791..10330
                     /locus_tag="VYN15_001520"
     CDS             9791..10330
                     /locus_tag="VYN15_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV1452824.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            10330..10593
                     /locus_tag="VYN15_001521"
     CDS             10330..10593
                     /locus_tag="VYN15_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV1452825.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            10590..11375
                     /locus_tag="VYN15_001522"
     CDS             10590..11375
                     /locus_tag="VYN15_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV1452826.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            11384..12172
                     /gene="divIVA"
                     /locus_tag="VYN15_001523"
     CDS             11384..12172
                     /gene="divIVA"
                     /locus_tag="VYN15_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV1452827.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            12520..15312
                     /locus_tag="VYN15_001524"
     CDS             12520..15312
                     /locus_tag="VYN15_001524"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV1452828.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT         4709 a         2891 c         3530 g         4558 t
ORIGIN      
        1 tctgttttaa aaacgaaaaa atcgaaaaag cttctctctt ttccataatt ttctactcaa
       61 attgtggtac aattaagagt aagattttaa gttagaaatg agactgattt gtatgagaaa
      121 atttaacagc cattcgattc cgattcggct taatttattg ttttcaatcg tcattttact
      181 ctttatgacc attattggtc gtttgttgta tatgcaggtt ttgaacaagg atttttacga
      241 aaaaaagcta gcttcagcta gtcagaccaa gattacaagc agttcagccc gtggggaaat
      301 ttatgatgct agtggaaaac ctttggtaga aaatacgtta aagcaggttg tttcctttac
      361 gcgtagcaat aaaatgacgg ctacagactt aaaagaaaca gctaaaaagt tactgactta
      421 tgtgagcatc agttctccaa atttgacaga acgccagctg gcggattact atttggctga
      481 tcctgaaatc tataaaaaaa tagtggaagc tctcccaagt gagaaacgct tggattcaga
      541 tggcaatcgt ctatccgaat cagaactgta taacaatgcg gtcgatagtg tacaaacgag
      601 tcaactaaac tatacagagg atgaaaagaa agaaatctat ctttttagtc agttaaatgc
      661 tgttggaaac tttgcgacag gaaccattgc gacagatcct ctaaatgatt ctcaggtggc
      721 tgttattgcc tctatttcaa aggagatgcc tggcattagt atttctactt cttgggatag
      781 aaaggttttg gaaacttccc tttcttctat agttgggagt gtatccagtg aaaaagctgg
      841 tctcccagcg gaagaagcag aagcctatct taaaaaaggc tattctctaa atgatcgtgt
      901 aggaacctcc tatttggaaa agcaatatga agagacctta caaggaaaac gctcggtaaa
      961 agaaatccat ctggataaat atggcaatat ggaaagcgtg gatacaattg aggaaggtag
     1021 taagggaaac aatatcaaac tgaccattga tttggccttc caagatagcg tggatgcttt
     1081 actgaaaagt tatttcaatt ccgagctaga aaatggtgga gccaagtatt ctgaaggtgt
     1141 ctatgcagtc gcccttaacc caaaaacagg tgcggttttg tctatgtcag ggattaaaca
     1201 tgacttgaaa acgggagagt tgacgcctga ttccttggga acggtaacca atgtctttgt
     1261 tccaggttcg gttgtcaagg cggcgaccat cagctcaggt tgggaaaatg gagtcttgtc
     1321 aggaaaccag accttgacag accagtccat tgtcttccaa ggttcagctc ccatcaattc
     1381 ttggtatact caggcttacg gttcattccc tatcacagcg gtccaagctc tggagtattc
     1441 atcaaatacc tatatggtcc aaacagcctt aggtcttatg gggcaaacct atcaacccaa
     1501 tatgtttgtc ggcaccagca atctagagtc tgctatggag aaactgcgtt caacctttgg
     1561 cgaatatggc ttgggtactg cgacaggaat tgacctacca gatgaatcta ctggatttgt
     1621 tcccaaagag tatagctttg ctaattacat tactaatgcc tttgggcagt ttgataacta
     1681 tacgccgatg cagttggctc agtatgtagc aactattgca aataatggtg ttcgtgtggc
     1741 tcctcgtatt gttgaaggca tttatggtaa taatgataag ggaggactgg gtgacttgat
     1801 tcagcaactg caaccgacag agatgaataa ggtcaatata tccgactccg atatgagcat
     1861 cttgcaccaa ggtttttatc aggttgccca tggtactagt ggattgacaa ctggacgtgc
     1921 cttttcaaat ggtgccttgg tatccattag cggaaaaaca ggtacagccg aaagctatgt
     1981 ggcagatggt cagcaagcaa ccaataccaa tgcggtggcc tatgccccat ctgataatcc
     2041 ccaaatcgct gtcgcagtgg tctttcctca taataccaat ctaacaaatg gtgtaggacc
     2101 ttccattgcg cgtgacatta tcaatctgta tcaaaaatac catccaatga actagaaagg
     2161 aaattatgct ttatccaaca cctattgcca agttgattga cagttattct aagttaccag
     2221 gtatcgggat taagacggct acgcgtctgg ccttttatac gattgggatg tctgctgatg
     2281 atgtcaatga atttgcaaaa aatctccttt ctgctaagag agaattgaca tattgttcta
     2341 tttgtggacg tttgacagac gacgatcctt gttctatctg tactgatccg actcgtgacc
     2401 agacaacaat tttagttctt gaggatagta gagatgtggc agccatggaa aatatccaag
     2461 aataccatgg actctatcat gtcctgcatg gcctcatttc tcctatgaat ggtatcagtc
     2521 cggacgatat caatctcaag agccttatga ctcgtcttat ggatagtgag gtttcagaag
     2581 tgattgtggc gactaatgct acagcggatg gtgaagcgac ttccatgtat ctttcacgtt
     2641 tgctcaagcc ggctggtatc aaggttacgc gtctagcacg aggtctcgct gtgggagcgg
     2701 acattgagta tgcggacgaa gtgacactct tacgagcgat tgaaaatcgg acagagttgt
     2761 aagtgtaggc aaatttacga actcccttca tttataaaaa atcaaagagg ctgaaaatcg
     2821 ttcctatcgg cctctttttg tatagtgtga tgagtaggat cgggttcaag ttttaaaaaa
     2881 ccaagcaaat atgatatact aaagagcgag tattctagta gaattaggac aaataatatg
     2941 aaacaaacga ttattctttt atatggtgga cggagtgcgg aacgcgaagt ctctgtcctt
     3001 tcagctgaga gtgtcatgcg tgcggtcaat tacgaccgtt tcacagtcaa gactttcttt
     3061 atcagtcagt caggtgactt tatcaaaaca caggaattta gtcatgctcc gggtcaagaa
     3121 gaccgtctca tgaccaatga aaccattgat tgggataaga aagttgcacc aagtgctatc
     3181 tacgaagaag gtgcagtggt ctttccagtc cttcacgggc caatgggaga agatggctct
     3241 gttcaaggat tcttggaagt tttgaaaatg ccttacgttg gttgcaacat tttgtcatca
     3301 agtcttgcca tggataaaat cacgactaag cgtgttctgg aatctgctgg tattgcccaa
     3361 gttccttatg tggctatcgt tgaaggcgat gatgtgactg ctaaaatcgc tgaagtggaa
     3421 gaaaaattgg cttatccagt cttcactaag ccgtcaaaca tggggtctag tgtcggtatt
     3481 tctaagtctg aaaaccaaga agaactccgt caagccttaa aacttgcctt ccgatatgac
     3541 agccgtgtct tggttgagca aggagtgaat gcccgtgaaa ttgaggttgg cctcttgggt
     3601 aactacgatg tcaagagcac gctacctgga gaagttgtca aggacgttgc cttttatgat
     3661 tacgatgcca agtatattga taacaagatt actatggata ttcctgccaa aatcagtgat
     3721 gatgtggtgg ctgtcatgcg tcaaaatgca gaaacagcct tccgtgccat tggtggcctt
     3781 ggtctatctc gttgcgattt cttctataca gataagggag agatttttct caacgagctc
     3841 aataccatgc caggtttcac ccagtggtct atgtacccac tactttggga caatatgggg
     3901 atcagctacc cagaactaat cgagcgtttg gttgaccttg ccaaggaaag ttttgacaag
     3961 cgcgaagcgc atttgatata aaattaaaga gagggtagaa gccagaacca tcactgcaag
     4021 gtgactagag ttctcggact tcagcccttt ttaaaggagt agaaatgaaa ttaacaatcc
     4081 atgaaattgc ccaagttgtt ggagccaaaa atgatatcag tatctttgag gacacccagt
     4141 tagaaaaagc tgagtttgat agtcgtttga ttggaactgg agatttattt gtgccactta
     4201 aaggtgcgcg tgacggtcat gactttatcg aaagagcttt tgaaaatggt gcggcagcaa
     4261 ccctgtctga gaaagaggtt gcaaatcatc cctacattct agtagatgat gttttgactg
     4321 cctttcaaca actagctgcc tactatcttg aaaaaacagc tgttgatgtc tttgcggtta
     4381 cgggttcaaa tggcaagaca acgaccaagg atatgttagc gcatttacta tcaacaacct
     4441 acaagaccta caaaacacaa ggaaactaca ataacgagat tggtcttcca tacacagttc
     4501 tccatatgcc tgaagggaca gaaaagttgg tcttggagat ggggcaggac cacttgggcg
     4561 atattcatct cttgtctgaa ttggctcgtc caaaaacagc catcgtgacc ttggttggag
     4621 aagcccattt ggcctttttc aaagatcgtt cggaaatcgc taaagggaaa atgcaaattg
     4681 cagatggcat ggcttcgaat tccttgctct tggcgccagc agattcgatt gtagaggact
     4741 acttgccaac tgataaaaag gtggtccgtt ttgggcaagg ggcagagttg gaaatcacag
     4801 acttggttga gcgtaaggac agtctgacct ttaaggctaa tttcttggaa caagcccttg
     4861 atttgccagt gactggtaag tacaatgcta ccaatgctat gattgcatcc tatgttgccc
     4921 tacaagaagg agtttcagag gagcaaattc atcaggcctt ccaaggtctt gaattgacgc
     4981 gtaatcgtac tgagtggaag aaagcagcca atggagcaga tatcctgtca gacgtatata
     5041 atgccaatcc aactgctatg aagctgattt tagagacttt ctctgccatt ccagccaatg
     5101 aaggtggcaa gaaaattgca gtgttggcgg atatgaagga gcttggtgac cagtctattc
     5161 aactccataa ccagatgatt ttgagccttt ctccagatgt gcttgatacc gttattttct
     5221 atggagaaga cattgctgaa ttagcccaat tggtcagtca aatgttccca attggccacg
     5281 tttactactt caagaaaaca gaagaccagg atcaatttga agacctagtc aagcaggtta
     5341 aggaaagcct tggagcctat gaccaaatct tgctaaaagg ttctaactct atgaatctag
     5401 ccaaattggt agaacgttta gaaaatgaag tcaagtgatt ttgtcaaaca tttacgtatt
     5461 tctaaatcca tttttaacaa ctagcatggt ataataaaat gcaggaaaat tttgaatcat
     5521 gaggaagact agatgaattt atgggatatt ttctttacga ctcaggcaac cgagccgccc
     5581 aaatttgacc ttttttggta tgttagccta tttacgctct tagccttaac cttttataca
     5641 gcccatcgct atcgtgaaaa gaaggtttac caacgatttt tccaaatctt gcagactgtt
     5701 cagttaatcc ttctttatgg ttggtactgg gtcaatcata tgccactgtc agaaagccta
     5761 cccttttacc attgccgtat ggctatgttt gtggtactct tgcttcctgg tcagtccaaa
     5821 tataaacaat actttgcatt attgggaaca tttgggacat tagcagcctt tgtttatcca
     5881 gtgccagatg cttacccttt tccacatatc accattctat cctttatctt tggtcattta
     5941 gcactcttgg ggaactctct agtttatcta ttgagacagt ataatgcgcg attgctggat
     6001 gtgaagggaa tttttctcat gacctttgcc ctaaatgcct tgatttttgt ggtcaatttg
     6061 gtgacaggtg gcgattacgg atttttgaca aaaccgccat tggttgggga tcacggtcta
     6121 gtagctaatt atttacttgt ttcaattgtg ctggtagcta ctatcagttt gactaagaaa
     6181 atcttagaat tctttttagc tcaagaagca gaaaaaatga ttgcaaagga agcttaacac
     6241 agagctttct tttttgctct tagagagttt ttacaagcag cttataaaat aagaatttct
     6301 gaatagacaa actcaaaaaa tggctgggaa atttaggaaa aaagcaagca cgattaaatt
     6361 ttttgtgtta taatattttg tgaatagcta tgcctatgtt tagctatgga ataatacgaa
     6421 gtgcgaaact tggaagatag agaggaagcg atgtaatggc tagagaaggc ttttttacag
     6481 gtctagatat tggaacaagc tctgtcaagg tgcttgtggc cgagcagaga aatggtgaat
     6541 taaatgtaat tggcgtgagt aatgccaaaa gtaaaggtgt aaaggatgga attattgttg
     6601 atattgatgc agcagcaact gctatcaagt cagccatttc ccaagcggaa gaaaaggcag
     6661 gcatttcgat taaatcagta aatgtcggct tgcctggtaa tcttttgcag gtagaaccaa
     6721 ctcaggggat gattccagta acatctgata ctaaggaaat tacggatcaa gatgttgaaa
     6781 atgttgtcaa atcagctttg acaaagagta tgacacctga ccgtgaagtc attaccttta
     6841 ttcctgaaga atttattgtg gatggtttcc aagggattcg tgacccacgt ggcatgatgg
     6901 gggttcgcct tgaaatgcgt ggtttgcttt atacaggacc tcgtactatc ttgcacaatt
     6961 tgcgtaagac ggttgagcgt gcaggtgttc aggttgaaaa tgttatcatt tcaccactag
     7021 caatggttca gtctgttttg aacgaagggg aacgtgaatt tggtgctaca gtgattgata
     7081 tgggggcagg tcaaacgact gtcgctacaa tccgtaatca agaactccag ttcacacata
     7141 ttctccaaga aggtggagat tatgtaacta aagatatctc caaggttttg aaaacctctc
     7201 gcaaattagc ggaaggcttg aaactgaatt acggggaagc ctatccgcct cttgcaagca
     7261 aagaaacctt ccaagtagag gttattggag aagtggaagc agtcgaagtg acggaagcct
     7321 acttgtcaga aattatttct gcacgaatca agcacatcct tgaacaaatc aagcaagaat
     7381 tagatagaag gcgtctattg gacctccctg gtggtattgt cttaatcggt gggaatgcca
     7441 ttttaccagg tatggttgag cttgctcagg aagtctttgg cgtccgtgtc aagctttatg
     7501 ttccaaatca agttggtatc cgtaatccag cttttgcgca tgtgattagt ttatcagaat
     7561 ttgcgagtca attaacagaa gttaatcttt tggctcaggg agcgataaaa ggtgagaatg
     7621 acttaagtca tcagccaatt agttttggtg ggatgctgca aaaaacagct cagtttgtac
     7681 aatcaacgcc tgttcaacca gctcctgctc cagaagtaga gtcggtggcg cctacagaac
     7741 caatggcgga tttccaacaa gcttcacaaa ataaaccgaa attagcagat cgtttccgtg
     7801 gcttgatcgg aagcatgttt gacgaataaa gaggaaaaat aaattatgac attttcattt
     7861 gatacagctg ctgctcaagg ggcagtgatt aaagtaattg gtgtcggtgg aggtggtggc
     7921 aatgccatca accgtatggt cgacgaaggt gttacaggcg tagaatttat cgcagcaaac
     7981 acagatgtac aagcattgag tagtacaaaa gctgagactg ttattcagtt gggacctaaa
     8041 ttgactcgtg gtttgggtgc aggaggtcaa cctgaggttg gtcgtaaagc cgctgaagaa
     8101 agcgaagaaa cactgacgga agctattagt ggtgccgata tggtcttcat cactgctggt
     8161 atgggaggag gctctggaac tggagctgct cctgttattg ctcgtatcgc caaagattta
     8221 ggtgcgctta cagttggtgt tgtaacacgt ccctttggtt ttgaaggaag taagcgtgga
     8281 caatttgctg tagaaggaat caatcaactt cgtgagcatg tagacactct attgattatc
     8341 tcaaacaaca atttgcttga aattgttgat aagaaaacac cgcttttgga ggctcttagc
     8401 gaagcggata acgttcttcg tcaaggtgtt caagggatta ccgatttgat taccaatcca
     8461 ggattgatta accttgactt tgccgatgtg aaaacggtaa tggcaaacaa agggaatgct
     8521 cttatgggta ttggtatcgg tagtggagaa gaacgtgtgg tagaagcggc acgtaaggca
     8581 atctattcac cacttcttga aacaactatt gacggtgctg aggatgttat cgtcaacgtt
     8641 actggtggtc ttgacttaac cttgattgag gcagaagagg cttcacaaat tgtgaaccag
     8701 gcagcaggtc aaggagtgaa catctggctc ggtacttcaa ttgatgaaag tatgcgtgat
     8761 gaaattcgtg taacagttgt tgcaacgggt gttcgtcaag accgcgtaga aaaggttgtg
     8821 gctccacaag ctagatctgc tactaactac cgtgagacag tgaaaccagc tcattcacat
     8881 ggctttgatc gtcattttga tatggcagaa acagttgaat tgccaaaaca aaatccacgt
     8941 cgtttggaac caactcaggc atctgctttt ggtgattggg atcttcgccg tgaatcgatt
     9001 gttcgtacaa cagattcagt cgtttctcca gtcgagcgct ttgaagcccc aatttcacaa
     9061 gatgaagatg aattggatac acctccattt ttcaaaaatc gttaagtaaa tgaatgtaaa
     9121 agaaaataca gaacttgttt ttcgagaagt tgcagaggct agtctgagtg ctaatcgaga
     9181 gagtggttcg gtctctgtca ttgcagttac caagtatgta gatgtaccga cagcggaagc
     9241 cttgcttccg ctaggtgttc atcatatcgg tgaaaatcgt gtagataagt ttctggaaaa
     9301 atatgaagct ttaaaagatc gagatgtgac ttggcatttg attggtacct tgcaaagacg
     9361 taaggtgaaa gatgtcattc aatacgttga ttatttccat gcattggact cagtaaagct
     9421 agcaggggaa attcaaaaaa gaagtgaccg agtcatcaag tgtttccttc aagtaaatat
     9481 ttctaaagaa gaaagcaaac acggtttttc gagagaggaa ctgctggaaa tcttgccaga
     9541 gttagccaga ctagataaga ttgaatatgt tggtttaatg acgatggcac cttttgaggc
     9601 tagcagtgag cagttgaaag agattttcaa ggcgacccaa gatttacaaa gagaaattca
     9661 agagaaacaa attccaaata tgcctatgac cgagttaagt atgggaatga gtcgtgatta
     9721 taaagaagcg attcaattcg gttccacttt tgttcgtata ggtacatcat tttttaagta
     9781 ggagagaacc atgtctttaa aagatagatt cgatagattt atagattatt ttacggagga
     9841 tgaggattca agtctccctt atgaaaaaag agatgagcct gtgtttactc cagtaaattc
     9901 ttcacaggaa ccggctctcc caatgaatca accttcacag tcggctggta caaaagagaa
     9961 caatatcacc agacttcatg caagacaaca ggaattggca aatcagagtc agcgtgcaac
    10021 ggataaggtc attatagatg ttcgttatcc tagaaaatat gaggatgcaa cagaaattgt
    10081 tgatttattg gcaggaaacg aaagtatctt gattgatttt cagtatatga cagaggtgca
    10141 ggctcgtcgt tgtttggact atttggatgg agcttgtcat gttttagctg gaaatttgaa
    10201 aaaggtagct tctaccatgt atttgttgac accagtgaat gttattgtaa atgttgaaga
    10261 tatccgttta ccagatgaag atcaacaggg tgagttcggt tttgatatga agcgaaatag
    10321 agtacgataa tgattttttt aattcgtatg atttataatg cagtggatat ttactccctg
    10381 attttggtag ccttcgctgt catgtcttgg tttccaggtg cctacgaatc cagtttaggt
    10441 cgttggattg tagcgttggt gaaaccagtg cttgctccct tgcaacgcct gcctttacag
    10501 atagcgggtc ttgatttatc tgtttgggtc gcgattgttt tggttcgatt tttaggagaa
    10561 aacctagtgc gttttctggc gatgatagga tgaataaagg gatttatcag catttctcca
    10621 tagaagatcg tccatttctt gacaagggaa tggaatggat aaagaaggta gaagatagct
    10681 atgctccttt tttaactcct tttatcaatc ctcatcagga gaagctatta aagattttgg
    10741 ccaaaaccta tggtcttgct tgtagcagta gtggggaatt cgtctcgagt gagtatgttc
    10801 gagttttatt atacccagat tatttccaac cagagttttc agattttgaa atatctctcc
    10861 aggaaattgt gtattccaat aaatttgaac atttaacgca tgctaagatt ttagggacag
    10921 tcatcaatca attagggatt gaacggaaac tttttggaga tatcctagta gatgaagaac
    10981 gggcgcagat tatgattaat cagcagtttc ttcttctctt tcaagatgga ctaaagaaaa
    11041 ttggtcgtat acctgtttcg ctggaggaac gtcctttcac cgagaaaata gataagctag
    11101 aacagtatcg agaactggat ttatctgtgt ctagttttcg attagatgtt cttttatcaa
    11161 atgttttgaa actatctagg aatcaagcaa accagttgat tgaaaagaaa cttgtccaag
    11221 taaattatca tgtggtagac aaatcagatt acactgttca agttggagac ttgattagtg
    11281 tgagaaaatt tggtcgcttg agattacttc aagataaggg acaaacgaaa aaagagaaga
    11341 aaaaaataac cgtccagtta ttattaagta agtgaggaat agaatgccaa ttacatcatt
    11401 agaaataaag gacaagactt ttggaactcg attcagaggt tttgatccag aagaagtcga
    11461 tgaattttta gatattgtgg ttcgtgatta cgaagatctt gtgcgtgcga atcatgataa
    11521 aaatttgcgt attaagagtt tagaagagcg tttgtcttac tttgatgaaa taaaagattc
    11581 attgagccag tctgtattga ttgctcagga tacagctgag agagtgaaac aggcggcgca
    11641 tgaacgttca aacaatatca ttcatcaagc agagcaagat gcgcaacgct tgttggaaga
    11701 agctaaatat aaggcaaacg agattcttcg tcaagcaact gataatgcta agaaagtcgc
    11761 tgttgaaaca gaagaattga agaacaagag ccgtgtcttc caccaacgtc tcaaatctac
    11821 aattgagagt cagttggcta ttgttgaatc ttcagattgg gaagatattc tccgtccaac
    11881 agctacttat cttcaaacca gtgatgaagc ctttaaagaa gtggttagcg aagtacttgg
    11941 agaaccgatt ccagctccaa ttgaagaaga accaattgat atgacacgtc agttctctca
    12001 agcagaaatg gaagaattac aagctcgtat tgaggtagcc gataaagaat tgtctgaatt
    12061 tgaagctcag attaaacagg aagtggaaac tccaactcct gtagtgagtc ctcaagttga
    12121 agaagagcct ctgctcatcc agttggccca atgtatgaag aaccagaagt agctccagtg
    12181 catccgacag gtccaacacc agctacagaa actgttgatt cagcaccggg atttgaagca
    12241 ccgcaagaat ctgttacaat tttataagaa atattctgag aacaatatct tatccttata
    12301 ttcccagcga gcaggagatg gtgtgagtcc tgcattccct atcgataaga ttatcctctc
    12361 aaaaactcaa gtctgaatct agtaagattt gacgttcccc acgttacggg ataagaggga
    12421 gaaagactaa aactttttcc gaataaaggt ggtaccacga ttttcgtcct ttttggaagt
    12481 cgtggttttt aatttgttat tatttataaa ggagatacca tgaaactcaa agacaccctt
    12541 aatcttggga aaactgaatt cccaatgcgt gcaggccttc ctaccaaaga gccagtttgg
    12601 caaaaggaat gggaagatgc aaaactttat caacgtcgtc aagaattgaa ccaaggaaaa
    12661 cctcatttca ccttgcatga tggccctcca tacgctaacg gaaatatcca cgttggacat
    12721 gctatgaaca agatttcaaa agatatcatt gttcgttcta agtctatgtc aggattttac
    12781 gcaccattta ttcctggttg ggatactcat ggtctgccaa tcgagcaagt attgtcaaaa
    12841 caaggtgtca aacgtaaaga aatggacttg gttgagtact tgaaactttg ccgtgagtac
    12901 gctctttctc aagtagataa acaacgtgaa gattttaaac gtttgggtgt ttctggtgac
    12961 tgggaaaatc catatgtgac cttgactcct gactatgaag cagctcaaat tcgtgtattt
    13021 ggtgagatgg ctaataaggg ttatatctac cgtggtgcca agccagttta ctggtcatgg
    13081 tcatctgagt cagcccttgc tgaagcagag attgaatacc atgatttggt ttcaacttcc
    13141 ctttactatg ccaacaaggt aaaagatggc aaaggagttc tagatacaga tacttatatc
    13201 gttgtctgga caacgactcc atttaccatc acagcttctc gtggtttgac ggttggtgca
    13261 gatattgatt acgttttggt tcaacctgct ggtgaagctc gtaagtttgt cgttgctgct
    13321 gaattattga ctagcttgtc tgagaaattt ggctgggctg atgttcaagt tttggaaact
    13381 taccgtggcc aagaactcaa ccacatcgta acagaacacc catgggatac agctgtagaa
    13441 gagttggtaa ttcttggtga ccacgttacg actgactctg gtacaggtat tgttcataca
    13501 gcccctggtt ttggtgagga cgattacaat gttggtattg ctaataatct tgaagtcgca
    13561 gtgactgttg atgaacgtgg tatcatgatg aagaatgctg gtcctgaatt tgaaggtcaa
    13621 ttctatgaaa aggtagttcc aactgttatt gaaaaacttg gtaacctcct tcttgcccaa
    13681 gaagaaatct ctcactcata tccatttgac tggcgtacta agaaaccaat catctggcgt
    13741 gcagttccac aatggtttgc ctcagtttct aaattccgtc aagaaatctt ggacgaaatt
    13801 gaaaaagtga aattccactc agaatggggt aaagtccgtc tttacaatat gatccgtgac
    13861 cgtggtgact gggttatctc tcgtcaacgt gcttggggtg ttccacttcc tatcttctac
    13921 gctgaagatg gtacagctat catggtagct gaaactattg aacacgtagc tcaacttttt
    13981 gaagaacatg gttcaagcat ttggtgggaa cgtgatgcca aagacctctt gccagaagga
    14041 tttactcatc caggttcacc aaacggcgag ttcaaaaaag aaactgatat catggacgtt
    14101 tggtttgact caggttcatc atggaatgga gtggtggtaa accgtcctga attgacttac
    14161 ccagccgacc tttacctaga aggttctgac caataccgtg gttggtttaa ctcatcactt
    14221 atcacatctg ttgccaacca tggcgtagca ccttacaaac aaatcttgtc acaaggtttt
    14281 gcccttgatg gtaaaggtga gaagatgtct aaatctcttg gaaatactat tgctccaagc
    14341 gatgttgaaa aacaattcgg tgctgaaatc ttgcgtctct gggtaacaag tgttgactca
    14401 agcaatgacg tgcgtatctc tatggatatc ttgagccaag tttctgaaac ttaccgtaag
    14461 attcgtaaca ctcttcgttt cttgattgcc aatacatctg actttaaccc agctcaagat
    14521 acagtcgctt acgatgagct tcgttcagtt gataagtaca tgacgattcg ctttaaccag
    14581 cttgtcaaga ccattcgtga tgcctatgca gactttgaat tcttgacgat ctacaaggcc
    14641 ttggtgaact ttatcaacgt tgacttgtca gccttctacc ttgattttgc caaagatgtt
    14701 gtttacattg aaggtgccaa atcactggaa cgccgtcaaa tgcagactgt cttctatgac
    14761 attcttgtca aaatcaccaa actcttgaca ccaatccttc ctcacactgc ggaagaaatc
    14821 tggtcatatc ttgagtttga aacagaagac ttcgtccaat tgtcagaatt accagaagtt
    14881 caaacttttg ctaaccaaga agaaatcttg gatacatggg cagccttcat ggactttcgt
    14941 ggacaagcac aaaaagcctt ggaagaagct cgtaatgcaa aagttatcgg taaatcactt
    15001 gaagcacact tgacagttta tccaaatgaa gttgtgaaaa ctctactcga agcagtaaac
    15061 agcaatgtag cacaactttt gatcgtgtct gagttgacca tcgcagaagg accagctcca
    15121 gaagctgccc ttagcttcga agatgtagcc ttcacagttg aacgtgctgc tggtgaagta
    15181 tgtgaccgtt gccgtcgtat cgacccaaca acagcagaac gcagctacca ggcagttatc
    15241 tgtgatcact gtgcaagcat cgtagaagaa aactttgcgg aagcagtcgc agaaggattt
    15301 gaagagaaat aagattgaaa agtctaggca aaattcaatt tgagaagaaa agacaactaa
    15361 ttttatagtc tattaaacgc attgtatcac gtttttgaac acctgatatg atgcgttttt
    15421 tatttatttt aaaaatttgc gaggtatgac tttttatact caacaagaat caaagagaaa
    15481 cttagcaagc taacagtagt aagataaaat aggaatttga tattagggat aagattggta
    15541 aatagtgtaa tatttttaca acaataaatt tatatagtta tttttggttt ctgaaaagta
    15601 ttatatttta tttcatatta tacaaatttt tattttataa tatcagaaaa tacttttttt
    15661 aaaagcaaat atgatacaat tttatttg
//
LOCUS       DAVLTT010000044        15428 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLTT010000044 DAVLTT010000000
VERSION     DAVLTT010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15428
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.044"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..960
                     /locus_tag="VYN15_001525"
     CDS             <1..960
                     /locus_tag="VYN15_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV1452829.1"
                     /translation="TNKILLMPDLFNYLLTGKFATEKSIASTTQLFDPRSQNWNQNIL
                     KLFELDSSLLPEIVSEGNVLGRIKKEYGLGDIPVVNVCSHDTASAIVSVPKTEGSLFI
                     SSGTWSLVGVELTSPILTTESFSYGFTNEVGKDGVITFLKNCTGLWIIEELRRSFERR
                     GKAYSFDDIRTMVEKEKENLPLIDTESTEFATESDMHKTLTEYLAYHHETREWTDGQL
                     FKIVYESLAETYRKAIELLEELTHKVYKRIYVIGGGARASYFNQMIADRTGKEVLTGL
                     TEGTAVGNIVVQLIAMGQLKGMEEAHHVIEEFLQLESYYSQKN"
     gene            1075..1713
                     /locus_tag="VYN15_001526"
     CDS             1075..1713
                     /locus_tag="VYN15_001526"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV1452830.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            1725..2165
                     /locus_tag="VYN15_001527"
     CDS             1725..2165
                     /locus_tag="VYN15_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV1452831.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            2158..2589
                     /locus_tag="VYN15_001528"
     CDS             2158..2589
                     /locus_tag="VYN15_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1452832.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            2580..3050
                     /locus_tag="VYN15_001529"
     CDS             2580..3050
                     /locus_tag="VYN15_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1452833.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYNSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            3075..3848
                     /locus_tag="VYN15_001530"
     CDS             3075..3848
                     /locus_tag="VYN15_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1452834.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            3845..4645
                     /locus_tag="VYN15_001531"
     CDS             3845..4645
                     /locus_tag="VYN15_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1452835.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            4704..6998
                     /locus_tag="VYN15_001532"
     CDS             4704..6998
                     /locus_tag="VYN15_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1452836.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTVFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            7008..10124
                     /locus_tag="VYN15_001533"
                     /pseudo
     CDS             7008..10124
                     /locus_tag="VYN15_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            10207..11973
                     /locus_tag="VYN15_001534"
     CDS             10207..11973
                     /locus_tag="VYN15_001534"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV1452837.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLADLGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFLTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            12119..13270
                     /locus_tag="VYN15_001535"
     CDS             12119..13270
                     /locus_tag="VYN15_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV1452838.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            13415..14299
                     /locus_tag="VYN15_001536"
     CDS             13415..14299
                     /locus_tag="VYN15_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1452839.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(14336..14494)
                     /locus_tag="VYN15_001537"
     CDS             complement(14336..14494)
                     /locus_tag="VYN15_001537"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452840.1"
                     /translation="MKIKEQTRKLATGCSKHRFEVVDKTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            14698..14949
                     /locus_tag="VYN15_001538"
     CDS             14698..14949
                     /locus_tag="VYN15_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1452841.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            14937..15227
                     /locus_tag="VYN15_001539"
     CDS             14937..15227
                     /locus_tag="VYN15_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452842.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEYKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT         5121 a         2274 c         3317 g         4716 t
ORIGIN      
        1 accaataaga ttcttttaat gccagatttg tttaattatc tcttgacagg taagtttgct
       61 acagaaaaaa gcattgcttc aacaactcaa ttatttgatc ctaggagtca aaattggaat
      121 caaaatatct taaaactatt tgaattggat tcatctttac ttcctgaaat tgtttcagag
      181 ggaaatgttc ttggaaggat aaaaaaggag tatggtttag gcgatattcc tgttgtgaat
      241 gtttgtagtc atgatacagc aagtgcgatt gtctcagtac ctaagacaga aggtagttta
      301 tttatttcat caggtacttg gtctttggtt ggagtggaac ttacttcacc gattcttact
      361 accgaatcct tcagttatgg atttacaaat gaagtcggta aagatggagt gattacattt
      421 ctgaagaatt gtacagggtt gtggatcata gaggaactaa gacgttcgtt tgaacgaaga
      481 gggaaagcct attcttttga tgatattagg acaatggtgg agaaagaaaa agaaaatctt
      541 cctctgattg atactgaatc aactgaattt gcaacagaat ctgatatgca caagactttg
      601 acagaatatc tagcttatca tcatgaaact agagagtgga cagatggaca actatttaag
      661 attgtttatg aaagcctagc tgaaacgtat aggaaagcga tagagttact agaagaacta
      721 actcataagg tttataagag gatatatgtg attggaggag gtgctagagc cagttatttt
      781 aaccaaatga ttgctgatag aactggtaaa gaggttctta caggtttgac tgagggtaca
      841 gctgtgggga atattgttgt gcagctcata gctatgggac aattaaaagg gatggaagaa
      901 gctcaccatg ttattgagga gttcctacaa ttagagagtt attactccca aaagaattaa
      961 aaagattgag agtttgtaaa tttgcctccc tcccccttct taagttttgt acaagaaggg
     1021 gggataattg gtgaattgaa aaatatttag tgttttgata tgaggaggat aagaatgtca
     1081 gatgtaaaac aagaattaat taagtatggc aagaagctgg tagaaacaga tttgacgaaa
     1141 ggaacaggtg ggaatctcag tgttttcgat cgtgaaaaac aattgatggc aattaccccg
     1201 tcgggtattg atttctttga aatcaaagaa tccgatattg tagtgatgga tattaatgga
     1261 aatgttgtag agggagaacg cttgccatct agcgaatggt atatgcattt gattcaatat
     1321 caaactcgtg atgatatcga tgcaattatc catgctcata caacttatgc aacagtatta
     1381 gcttgtctca gagaaccact tccggcgagt cattatatga ttgcagtggc agggaaagat
     1441 gttcgggtag ctgagtatgc aacatatggt acgaaagaat tggctgtgaa tgcagctaaa
     1501 gcaatggaag gtcgtagagc agttttacta gcgaatcatg gaattttagc aggtgcacaa
     1561 aatttattga atgcatttaa tattgttgaa gaagttgaat attgtgcaaa aatttattgt
     1621 ttagctaaga attttggaga gccagtagtt cttcctgatg aggagatgga tttaatggca
     1681 gaaaaattta aaacatacgg tcagagaaaa tagggaggat attaatgtta aaacatatac
     1741 cgaaaaatat ttctccagat ttattgaaga ctttaatgga aatgggacat ggagatgaaa
     1801 tagtattagc tgacgcgaat tatccttctg cctcatgtgc aaataagcta attcgttgtg
     1861 atggtgtaaa tattccagaa ttattagatt ccattctgta tttaatgcca ttagatagtt
     1921 acgtcgatag ttcaattcag tttatgaacg ttgtttcggg tgatgatatt cctaagatat
     1981 ggggtaccta tagacagatg attgaaggtc atggtacaga tcttaaaacg attacttatc
     2041 ttagaagaga agacttttat gaacgtagta agaaagctta tgctattgtt gctacaggag
     2101 aaacttcact ttatgctaat attatcctta agaaaggagt agttgttgaa agagaaaatg
     2161 tttaatagag gaattttagt tgccagtcat ggtaattttg ctagcggagc tctcatgacc
     2221 gcagaaatgt ttgttggtga gacaacaaat gatagagtta ggacattagg tttgatgcct
     2281 ggagagaata ttgtagagtt tgagcattat tttaaaaatc aagtggatga actgttagac
     2341 tcaaatcaag aggttatcgt tttgactgac ttgattggag gaagtcctaa taatgtggct
     2401 ttgtcacggt ttttaaattt ggattcagtt gatattgtaa cagggtttaa tatccctctc
     2461 ctagtggaat taatatcaag ttatgattca aaaatcaatt tagaagaaat tgttcacaat
     2521 gctcaaaata gtttgtttaa tgttaaacaa caacttaacg tagaggagga agaagattta
     2581 tgtctataga gtttgttcgt attgatgacc gtctggtaca tggtcaagtt gtcactacgt
     2641 ggctaaaaaa gtatgatatt gagcaagtta tcattgttaa tgatcgcatc tcagaagata
     2701 aaacacgaca atctatttta aagatttctg caccggtagg tttaaaaatt gttttcttta
     2761 gtgtaaaacg gtttgtggaa gttttaaact ctgtgccaat aaaaaagaga acaatgctga
     2821 tatatacaaa tccaaaagat gtgtataatt ctattgaagg aaatttaaaa ttggagtacc
     2881 tcaatgtagg acagatgagt aaaacggagg aaaatgaaaa ggtaacggga ggtgtagctc
     2941 taggtgaaga agacaaatat tattttaaga aaatagttga taagggaacg agagttgaaa
     3001 ttcaaatggt tcctaatgat aaagttacaa tgttggaaaa atttttataa aaataattta
     3061 aggaggtaca gtatatgcta ttcacacaag cattactggt gacattagtt gggattattg
     3121 ccactattga ctataatgga ccgttattta tgattcaccg tccgttagtt acaagtgcaa
     3181 tggttggctt agtattagga gatttcaccc aaggtgttct tattggttca gctcttgaat
     3241 taacttggct cggtgtaaca ggtattggag gttatactcc accagatact atttcaggtg
     3301 cgattattgg tactgcattt ggtattttat ctggtcaagg agaaactgct ggtatcgcta
     3361 tagcagttcc aattgcagtt gctacccaac agttggatgt tcttgcaaaa actttagatg
     3421 tttattttgt gaaaaaagct gataatgatg ctaaaaacgg agattattca aagatcggtt
     3481 tttatcatta ttcaagtttg gttttaatca cgttatttaa aattgtacca attttcctag
     3541 ctattatgct tggaggggaa tatgtggcag acttgtttgc taaggttcca ccaatcgtta
     3601 tgcagggact taactctgca ggtgctttac taccttcaat tggttttggt atgcttttaa
     3661 atatgatgct caagaaaaat atgtgggtat tcttgttgat tggattcatt tgttctgtgt
     3721 atggaggaat gtcaaccatt gggatctcac tagttggtat tgcggtagca tacttctacg
     3781 atatgattgg aagcaaacca caagaaacaa cttcaagtag tgatgttgag gaggatcttg
     3841 atctatgatg aataataaag taactaaagt tgaacttaaa aaagttttca aacgaagttt
     3901 tatgtatggt tcttcatgga actatgagag aatgcagaac ctaggttttc tatatacaat
     3961 tcttccagta ttgaaaaaac tatacccaga caaagattca gcttctcctg caatgaaacg
     4021 tcaccttgag tttttcaata ctcatcaaac agcggcacca tttattcttg gagttacttc
     4081 cgctatggaa gaacaagaag gaaatgaagg tgcagcttca attactggta ttaaagttgg
     4141 cttgatgggg ccactggctg gtctaggaga tagtttgttc tggctgacac tagttcctat
     4201 ctgttttagt attggtgcgt cttattctaa agacggcggt gctttaggta tctttatcgc
     4261 cttaatattg tttaatatta ttaatattcc tgttaaatat ttcggtttga aatatgggta
     4321 tactaagggt tctagtctta tccaagaaaa taatacaaaa ggaacattga atcgcgttac
     4381 gagtatggcg acagcattag ggctagtact agtgggtggt ttgattccat caatggttgg
     4441 tattaatttt ggattagaat ttaagcaggg ggaacttgtt atttctgttc aagaaatgat
     4501 tacaaaatta attccaggat ttatccctat ggctttgact ttattaatgt gtaaattaat
     4561 tagaaaagga aagaatccgg ttgtactaat ctttagtgtt atggctattg gagttattct
     4621 agttgtttta ggaattttga agtagtagaa agtgtggagg tggtatttgg gatatcacct
     4681 ccattttgga agagaggtaa agagtgaaat tatggtataa gaaagctgcc gcaaattgga
     4741 atgaagcctt gccgattggg aacggtcatt taggtggtat gatttatggt tcagctacaa
     4801 aagaatgtat tcaactaaac gatgagacta tttggtatag aggaaagtca gatagaaata
     4861 atccagactc actattgcat cttaaaaaaa ttcgggaata tcttttagat ggagaaattc
     4921 agaaagccga agaattgata aagttaacag tgtttgctac cccaagagat caaagccact
     4981 atgaattact tggggaactt tacattgagc atatagatat tcagtcttgt gctctttcat
     5041 tgtatgaaag agagctagat ttagatacag ctatttctaa tgttgtgttt gagcctaata
     5101 gttgtaattt acaaataaaa agagaatatt ttacgagttt taataagaat attttatgtt
     5161 gccgtatagt gtcatcagtt caaaacacat taaatttaaa cattaatttg ggtagaaata
     5221 aacggtttaa tgacgaagta tctaaactgg attcaagtac aattttaatg tcggcctctg
     5281 ctggaggtag aaaaggtgtt cagtttaaag tagtatgtca ttctaaggtt acggatggtg
     5341 aagtaagtgt attgggagag acaatagtta ttcggaatgc tacagaggta tttctttatc
     5401 tcaaatcaat gacggattat tggggaaata tagatatttc ttctcttcag ggagaattta
     5461 gtagtattga ttactttaca gaaaaagatg aacatgtaaa aaaatatcag gagcaattta
     5521 atagagttga ttttaaacta gactatagta aaggttgtct tagcattcca acgaatctac
     5581 ttcttgaaaa cactaaaaag tatagtaact acttgactaa cttgttattt cattatggaa
     5641 gatatctgtt aatatcgtct agtcaaccga atggtttacc tgccaatctt caaggaatat
     5701 ggtgtgatga attaaatcca atttggggtt ctaaatatac gattaatatt aatactcaaa
     5761 tgaattattg gatggtaggt ccatgtgatt taccagaagt agaatatcca ttatttgata
     5821 tgctcgaaag aatgagagaa ccgggaagac taaccgctaa gaaaatgtat ggagctagag
     5881 gttttacagc acatcataat acggatggtt ttggcgatac ggctccccaa tctcatgcca
     5941 tgggggctgc aatttgggta ttaactattc catggttatg tactcatatt tgggaacact
     6001 atttatattt ccaagatgag cgtattctta cggaacattt tgaaatgata aaagaagcat
     6061 ttcttttctt tgaagattat ttatttgagg tggatggcta cttgatgaca ggtccaagtg
     6121 tctcaccgga aaataaatat cgcttaaaaa atggtattga aggaaatgct tgtctatcat
     6181 ctacaattga taatcaaatt ttaagatatt tttgtgattc atgcattgga attgcaaaac
     6241 aattaggaga caattcggat tttattagtc gtgtgaagga gttaaaaaag aaattaccta
     6301 gaacaaaaat aggtagtaat gggcaaatac aagaatggct agaggattat gaagaagtag
     6361 agcctggtca tagacacatt tcacctctat ttgggcttta tccttataat gagattgata
     6421 ttcataaaac tccggaatta gcagaagcag ctaaaatcac tatcaatagg agattatcaa
     6481 acgctaactt tttatcttca caggataggg agcaagcgat taataattgg ttagtaagtg
     6541 gtttgcatgc tagtacacaa acaggttgga gtgctgcatg gctgattcat ttttttgcga
     6601 gactatatca aggtgaacct gcttataacc agattaatgg tttgttaaat aatgcgactc
     6661 ttggcaattt atttcttgac catccaccat ttcaaattga tggtaattta ggtttggtga
     6721 gtggaatttg tgaattatta gtacagagcc atcataattg gttatcacta attccagctt
     6781 taccttctgc ttggtcagaa ggagaagtga aaggtttcag agtaagagga ggatataagg
     6841 tatcgtttgc ttggaaaaat ggggatataa cattcctaaa attggaagga ggaaacaaag
     6901 atcaaaaagt aagagtaaga atatatggca aaaatactga tgtacaaaat attgaattgg
     6961 tatttaattc agaaaaaatt attgagttaa atttttaggt ataagtcatg aataaagaaa
     7021 aaataaaaag aaaattaatc acaatactgt ttgtatgtat tgggatgtta tgttttggat
     7081 tgttagcagg agttaaggct gataatcgtg ttcaaatgag aacgacgatt aataatgaat
     7141 cgccattgtt gctttctccg ttgtatggca atgataatgg taacggatta tggtggggga
     7201 acacattgaa gggagcatgg gaagctattc ctgaagatgt aaagccatat gcagcgattg
     7261 aacttcatcc tgcaaaagtc tgtaaaccaa caagttgtat tccacgagat acgaaagaat
     7321 tgagagaatg gtatgtcaag atgttggagg aagctcaaag tctaaacatt ccagttttct
     7381 tggttattat gtcggctgga gagcgtaata cagttcctcc agagtggtta gatgaacaat
     7441 tccaaaagta tagtgtgtta aaaggtgttt taaatattga gaattattgg atttacaata
     7501 accagttagc tccgcatagt gctaaatatt tggaagtttg tgccaaatat ggagcgcatt
     7561 ttatctggca tgatcatgaa aaatggttct gggaaactat tatgaatgat ccgacattct
     7621 ttgaagcgag tcaaaaatat cataaaaatt tggtgttggc aactaaaaat acgccaataa
     7681 gagatgatgc gggtacagat tctatcgtta gtggattttg gttgagtggc ttatgtgata
     7741 actggggctc atcaacagat acatggaaat ggtgggaaaa acattataca aacacatttg
     7801 aaactggaag agctagggat atgagatcct atgcatcgga accagaatca atgattgcta
     7861 tggaaatgat gaatgtatat actgggggag gcacagttta taattttgaa tgtgccgcgt
     7921 atacatttat gacaaatgat gtaccaactc cagcatttac taaaggtatt attcctttct
     7981 ttagacatgc tatacaaaat ccagctccaa gtaaggaaga agttataaat agaacaaaag
     8041 ctgtattttg gaatggagaa ggtaggatta gttcattaaa cggattttat caaggacttt
     8101 attcgaatga tgaaacaatg cctttatata ataatgggag atatcatatt cttcctgtaa
     8161 tacatgagaa aattgataag gaaaagattt catctatatt ccctaatgca aaaattttga
     8221 ctaaaaatag tgaggaattg tctagtaaag tcaactattt aaactcgctt tatccaaaac
     8281 tttatgaagg agatgggtat gctcagcgtg taggtaattc ctggtatatt tataatagta
     8341 atgctaatat caataaaaat cagcaagtaa tgttgcctat gtatactaat aatacaaagt
     8401 cgttatcgtt agatttgacg ccacatactt acgctgttgt taaagaaaat ccaaataatt
     8461 tacatatttt attgaacaat tacaggacag ataagacagc tatgtgagca ttatcaggaa
     8521 attttgatgc atcaaaaagt tggaagaaag aagaattaga gttagcgaac tggataagca
     8581 aaaattattc catcaatcct gtagataatg actttaggac aacaacactt acattaaaag
     8641 ggcatactgg tcataaacct cagataaata taagtggcga taaaaatcat tatacttata
     8701 cagaaaattg ggatgagaat acccatgttt ataccattac ggttaatcat aatggaatgg
     8761 tagagatgtc tataaatact gaagggacag gcccagtccc tttcccaaca ccagataaat
     8821 ttaatgatgg taatttgaat atagcatatg caaaaccaac aacacaaagt tctgtagatt
     8881 acaatggaga ccctaataga gctgtggatg gtaacagaaa tggtaatttt aactctggtt
     8941 cggtaacaca cactagggca gataatccct cttggtggga agtcgatttg aaaaaaatgg
     9001 ataaagttgg gcttgttaaa atttataatc gcacagatgc tgagactcaa cgtctatcta
     9061 attttgatgt gattctatat gacaataata gaaacgaagt tgctaagaaa catgttaata
     9121 atttgtcggg tgaatctgtt agtctagatt tcaaagaaaa aggagcaagg tatattaaag
     9181 ttaaattact aacgagtgga gtgcctttga gtttagcaga agtagaggtt tttagagaat
     9241 cagatggtaa gcaatctgaa gaggatatag ataaaataac agaagataaa gtagtctcta
     9301 caaataaggt agctactcaa agttcaacca attatgaggg tgtagctgct ttagcagttg
     9361 atggtaataa agatggagat tacggacatc attcggtgac tcatactaag gcagattcta
     9421 acgcttggtg gcaggttgat ctgggagaag agtttacggt ttctaaagtt gatatttata
     9481 atagaacaga tgccgaacct cagcgtttat ctaattttga tgttattttt ctatcttcat
     9541 caggagaaga agtttttaga agacattttg ataaagtagt tgatggtttg ttatctttaa
     9601 aagtaccttc tgtaggggct aagctagtca aaatagaatt aaaatcagca gctattccgt
     9661 taagtttagc ggaagttgaa gtctatggtt caaagagaac tccgaagaaa ctttctaata
     9721 ttgcattaac caaagaaact cgacagagtt caacggatta caatggtttt tctcgtctag
     9781 cagttgatgg aaataaaaac ggagattatg gtcatcattc agtgactcat accaaaggag
     9841 attctccttc atggtgggag atagatttag cacaaaccga agaattagaa aagttaatta
     9901 tttataatag aacagatgct gaaattcaga gattatcaaa ttttgatatt attatatatg
     9961 attcaaataa tcatgaagtt tttaaacaac atattgacag tttagaaagc aataatctat
    10021 ccatagactt aaaagggctg aagggaaaaa aggttagaat ttctttgaga aacgcaggaa
    10081 ttcctttaag tttagcagag gtagaggttt atacttataa gtaattttaa aaattatcac
    10141 ccaggctacc gtaaatataa tggcgatggt agtatgaaag aaacagaaaa ataagaggaa
    10201 aatagtatga ttcaacatcc acgtattggt attcgtccga ctattgatgg tcgtcgtcaa
    10261 ggtgtacgcg aatcacttga agtgcaaaca atgaacatgg ctaaaagtgt ggcagatttg
    10321 atttcaagca cattgaaata tccagatggg gaacctgtgg aatgcgtgat ttctccatct
    10381 actattggcc gtgtaccaga ggctgcagct tcccatgagt tgtttaaaaa atcaaatgtt
    10441 tgcgcaacaa ttacagttac accatgctgg tgttatggta gtgaaactat ggatatgtct
    10501 ccagatattc ctcatgctat ttggggattt aatgggacag aacgcccagg agctgtctat
    10561 cttgcagctg tactagcttc acatgctcaa aaagggattc cagcctttgg gatctatggt
    10621 agagatgttc aggaagctaa tgatacagct attccagaag atgtcaaaga aaaactttta
    10681 cgttatgcgc gggcagctct tgcaactggc ttgatgagag acactgctta cctatcaatg
    10741 ggtagtgttt cgatggggat tggtggttct attgtaaatc cggatttctt ccaagaatac
    10801 ttaggaatgc gaaatgaatc ggtagatatg acggagttca cacgccgtat ggaccgtggt
    10861 atttacgacc ctgaagagtt cgaacgtgcg ctcaaatggg tgaaagaaaa cgtaaaagaa
    10921 ggattcgacc ataaccgtga agaccttgtt ttaagccgtg aagaaaaaga tagacaatgg
    10981 gaatttgtta ttaagatgtt catgattgga cgtgacttaa tggttggtaa cccaagactt
    11041 gctgaccttg gttttgaaga agaagcagtt ggtcaccatg ctttagtagc tggtttccaa
    11101 ggtcaacgcc agtggacaga ccatttccca aatggggact ttatggaaac tttcctcaat
    11161 actcagtttg actggaatgg tattcgaaaa ccatttgtat ttgcgacaga gaatgattca
    11221 ctaaatggtg tgtctatgct ctttaattat ctattaacaa atactccaca aatctttgct
    11281 gatgtgcgca cttattggag tccagaggct gttaaacgtg taacgggaca tactttagag
    11341 ggttgtgctg cagctggctt cttacatcta atcaactctg gttcttgtac attggatggt
    11401 acagggcaag ctactcgaga tggcaaacct gttatgaaac cattctggga gttggaagaa
    11461 agtgaagtgc aggctatgct tgaaaataca gacttcccac cagcaaaccg cgaatacttc
    11521 cgtggaggag gattcttaac tcgtttcttg acgaaggggg atatgccagt aacaatggta
    11581 cgtctcaatc ttctaaaagg ggttggtcca gtgctacaaa ttgcagaagg ttatacactt
    11641 gaacttcctg aagatgttca ccatacttta gataatcgta cagatccagg atggccaact
    11701 acttggtttg ctccacgttt gacaggaaaa ggtgctttca agtctgtcta tgacgtcatg
    11761 aataattggg gagctaatca cggagccata acatatggac acattggagc agacttgatt
    11821 accttggctt ctatgttgag aattcctgtc aatatgcata atgtacccga agaagatatc
    11881 tttagaccta aaaattggtc cttatttgga acagaagatc tagaatcagc agactatcgt
    11941 gcatgtcagt tattgggacc actacataaa taaaacttgt ttatatagga ggtgaactta
    12001 cgtccctcct atccttttaa aaagatttgt taaacaattc acaaataatt gaaaacgaat
    12061 acaaaaagta atataatgat gttaaataga tagcgcggag gcgcaggagg aaaattatat
    12121 ggctacattt tatgttccgg cagtcaacct tattggaaaa ggtgttgtaa atgaagtggg
    12181 tccttatatc aaggaacttg gctataaaaa ggcacttttg gttacagata agtacatcga
    12241 aggcagtgat attttaccta aggttttaaa accactggat acagaaggaa tcgaatatgt
    12301 catctttagc gatgtagagc caaaccctac ttgtaaaaat gtcacagatg gggtagctgc
    12361 tttgcaagaa catggctgtg actttatcat cagtcttggc gggggttctc cacaggatgc
    12421 agctagttgt atttctatca tggctacaaa tggtggaaaa ccacaggatt atgaagggct
    12481 tcataagtct gctaaaaaag gcttgccagt tgtggctatc aatacaacgg caggaacttc
    12541 tgcagaaatc actattaact atgtgattac tgatgaagaa cgcaaggtta agatggtaat
    12601 ggttgacaag aatagccttg ctcttatctc tgttaatgac ccggaactca tgctttccaa
    12661 acctaaaggc ctgactgctg ctactggtat ggatgctctg actcacgctg ttgaagcttt
    12721 ggtaacacct ggtgcttatg atgtaaccaa gaaactgtct attggtgcta ttgagcttat
    12781 caaggaatat cttcctcgtg ctgtagaaaa tggacatgat attgaagcgc gtgaaggtat
    12841 ggtcaatgcc atcttccttg gtggtatgag ctttaataat gctggtcttg gttatgttca
    12901 ctcaatggct caccaactcg gtgcagtata taatttgcca catggtgttt gctgtgccat
    12961 gttgctacca gttatagaac gtgaaaatgc taaacgtgta ccagaagctt tccgcaatgt
    13021 tgccaaagcc ttgggacttc atgtagaagg taaatcagat caagaatgtg ccgattatgc
    13081 gattgttgag attgagaagc tttctgagac agtaggtatt cctaagaaac tgactgaact
    13141 tggtattgaa gaaaaagatt tcgactttga atacctttct aagaatgcct tgattgatgc
    13201 ctgcgcacca ggaaatccat ttatgccaac cttagaagaa acgattgcct tttataaaga
    13261 gttattttag caagagattg gacgacaata ggacaattca cctctaatta ttgacatttc
    13321 aggaaaaatc gcagtaaaaa cggcacagcc ttctttaaat gtgctataat actagaaaaa
    13381 tacttgtgga ggttccatta tggcaatatt tttcatgatt tttctgattg tttgtgtgct
    13441 cctattggtg atagtcacac tgagtacagt ttatgtggtt cgtcagcagt cggtggcgat
    13501 tattgaacgc tttgggaaat accaaaaggt tgccaatagc ggtattcata ttcgcttgcc
    13561 ttttgggatt gactcgattg cagcacggat tcagttgcgc ttgttgcaaa gtgatattgt
    13621 ggttgagact aagaccaagg acaatgtgtt cgttatgatg aatgtagcga ctcagtaccg
    13681 tgtcaacgag cagagcgtga cagatgctta ctataaactc atacgtccag aatctcagat
    13741 taaatcttat atcgaagatg ctcttcgctc ttctgttcca aaattaacct tggatgaatt
    13801 gtttgagaaa aaagatgaga ttgcccttga agttcaacac caagtagcag aagaaatgac
    13861 cacttacggc tacattatcg tgaaaacctt gattaccaag gtcgaaccgg atgcagaagt
    13921 taagcaatcc atgaatgaaa tcaatgcggc gcaacgtaag cgggtcgcag cacaagaatt
    13981 ggcggaagct gacaagatta aaattgtcac tgcagctgaa gccgaagcag aaaaagaccg
    14041 ccttcatggt gtggggattg cccaacaacg taaggcgatt gtggatggat tggcagagtc
    14101 tatcaccgaa ctcaaggaag ccaatgttgg catgacagaa gaacaaatca tgtctatcct
    14161 cttgaccaac cagtatttgg ataccttgaa tacctttgcc tctaaaggaa atcaaaccat
    14221 ctttttacca aatactccaa atggtgtgga tgatatccgt acacaaatct tgtcagccct
    14281 tcgcgctgag aagaaataat agactaatac tcttcgaaaa tctcttcaaa ccacgtcagc
    14341 gtcgtcttgc cgtatagatg ttactgactt cgtcagttct atctgcaacc tcaaaacagt
    14401 gttttgagct gacttcgtca gtcttatcta ctacctcaaa acggtgtttt gagcaacctg
    14461 tggctagttt cctagtttgc tctttgattt tcattgagtg caaagagctt ggcaacaggc
    14521 tctttttgta ttgcgtttat taagaaaaac aaaaaacatc gatatacatt taactaaaaa
    14581 ttattgtatg ttatctccct taattaggaa tgataaggga ataactagaa agatttgtga
    14641 atacaaacta tttctgatat acaaaatata cagtaataat gaatgatggg agatgggatg
    14701 aaagaatttc aatttgagag aaagcagcgt ttttctttga ggccatatgc aataggagct
    14761 tgttcggtct tgctaggaac gagtttattt tttgctggta tgggtgctca gcctgtacag
    14821 gatacagaaa cgagttcagc actaatttca agtcattatt tggatgagca ggatttatct
    14881 gaaaagctga aatctgagtt gcaatggttt gaattagaaa acaagctttt gaacttatgg
    14941 gagcattagg ttactatgaa ggatttgttc cttatgtttc aaatcaatac aaaaaccaag
    15001 ctgaagaaga atacaaaccg ctatctgata aatatatttt cgaaaaaatc ttaggaaaaa
    15061 catatgcagc cttcaaaaaa gatcaaatta atgagcgtgt cgagaaatta ggtaagttaa
    15121 aacctattac aataaattac aacggaaaat cagaagtaat tgatagtaaa gaaaaattac
    15181 aagagcttat gaataaagcc gttaaagacg aagtggctca aatatagtaa aatgaaataa
    15241 gaacaggaca aatcgatcag gacagtcaaa tcgatttcta aaaatgtttt agaagtagag
    15301 gtgtactatt ctagtttcaa tatactataa aatcaggcaa taccacggct aaaaagtttg
    15361 agtttatcga aacaccagtg caaaaactga aaaaagcgat ttataaagct catctcaaag
    15421 attcagat
//
LOCUS       DAVLTT010000045        14421 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLTT010000045 DAVLTT010000000
VERSION     DAVLTT010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14421
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.045"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(<1..185)
                     /locus_tag="VYN15_001540"
     CDS             complement(<1..185)
                     /locus_tag="VYN15_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452843.1"
                     /translation="MLVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLL"
     gene            complement(193..562)
                     /locus_tag="VYN15_001541"
                     /pseudo
     CDS             complement(193..562)
                     /locus_tag="VYN15_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
     gene            1320..1640
                     /locus_tag="VYN15_001542"
     CDS             1320..1640
                     /locus_tag="VYN15_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1452844.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVETYYQ
                     PKER"
     gene            complement(2143..2523)
                     /locus_tag="VYN15_001543"
     CDS             complement(2143..2523)
                     /locus_tag="VYN15_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HEV1452845.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            complement(2669..4021)
                     /locus_tag="VYN15_001544"
     CDS             complement(2669..4021)
                     /locus_tag="VYN15_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HEV1452846.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLEKLRAKEAIFQKFEQSLNEKYNHLSNSGEEQEYYGKVEYYLSQLNSENYNN
                     GTQYSKIQDEYTKLNKITAERNQLDADLQTLQNELIQLQQQGDSSSLSDTTSDDDKAK
                     LETKISEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNDPTSQAYNIYAQLISEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILASNEGTLHYLVPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKVDVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVILQKDMPVEVQIVYDKETYLDWILEMLSFKQ
                     "
     gene            complement(4018..4485)
                     /locus_tag="VYN15_001545"
     CDS             complement(4018..4485)
                     /locus_tag="VYN15_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1452847.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINRFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            complement(4478..6697)
                     /locus_tag="VYN15_001546"
     CDS             complement(4478..6697)
                     /locus_tag="VYN15_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEV1452848.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDITLSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYEDMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIMDKTTIVVAHRLSTILR
                     CDKICFLENGTIVEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDTEEVTYG"
     gene            7163..8026
                     /locus_tag="VYN15_001547"
     CDS             7163..8026
                     /locus_tag="VYN15_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1452849.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILSHLKK
                     EVEIYYQAKER"
     gene            complement(8078..8665)
                     /locus_tag="VYN15_001548"
     CDS             complement(8078..8665)
                     /locus_tag="VYN15_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1452850.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            8907..9578
                     /gene="sdaAB"
                     /locus_tag="VYN15_001549"
     CDS             8907..9578
                     /gene="sdaAB"
                     /locus_tag="VYN15_001549"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV1452851.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            9587..10459
                     /gene="sdaAA"
                     /locus_tag="VYN15_001550"
     CDS             9587..10459
                     /gene="sdaAA"
                     /locus_tag="VYN15_001550"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV1452852.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            10481..11113
                     /locus_tag="VYN15_001551"
     CDS             10481..11113
                     /locus_tag="VYN15_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1452853.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEALQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            11163..11330
                     /locus_tag="VYN15_001552"
     CDS             11163..11330
                     /locus_tag="VYN15_001552"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452854.1"
                     /translation="MKIKEQTRKLAAGSSKHCFKVVDRTDEVSSKHCFEVVDRTDEVS
                     NHIRQGDVDVV"
     gene            complement(11415..13265)
                     /locus_tag="VYN15_001553"
     CDS             complement(11415..13265)
                     /locus_tag="VYN15_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1452855.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPECIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(13307..14371)
                     /locus_tag="VYN15_001554"
     CDS             complement(13307..14371)
                     /locus_tag="VYN15_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1452856.1"
                     /translation="MTQNVESLLVSIVISAYNEEKYLPGLIEDLKNQTYPKENIEILF
                     INAISTDGTTAIIQQFIKEDTEFNSIRLYNNPKKNQASGFNLGVKHSVGDLILKIDAH
                     SKVTETFVMNNVAIIQQGEFVCGGPRPTIVEGKGKWAETLHLVEENMFGSSIANYRNS
                     SEDRYVSSIFHGMYKREVFQKVGLVNEQLGRTEDNDIHYRIREHGYKIRYSPSILSYQ
                     YIRPTFKKMLHQKYLNGLWIGLTSHVQFKCLSLFHYVPCLFVLSLVFSLALLPITFVF
                     ITLLLGAYFLLLSLLTLLTLLKHKNGFLIVMPFLLFSIHFAYGFGTIVGLIRGFKWKK
                     EYKRTIIYLDKISQINKNML"
BASE COUNT         4610 a         2976 c         2308 g         4527 t
ORIGIN      
        1 cttaataata aatttgctcc actgattgct atcaatattt caattggtaa aaaatagtaa
       61 ttccaaataa aatgagaaat cagcaatgat agaaaaataa caatatcaat tttcctgttg
      121 ttgacatact ctgtaatttt atggtacagg aatgcaacaa taactgaaat taaaacaacc
      181 aacataagat tattaaccta ttctcaattg actatcacgt cgcccatccc agccatcaat
      241 aatattggta aaaatccaat cagctccagc accaattcca gcagatgcaa tacttctaat
      301 aacagtattt gcaaaagcat ttccaatatg aattcctaat actcctaaac ctttaacaat
      361 cccagctacc agtgcggagc gtaatccata agatgcaaga actagttgaa ggcctccacc
      421 tcctgctgct gctaatgctg catatgctgc accagtaatg gctcctgtaa ttgcccacct
      481 gggtatatat agccccccca tcaaggtaca tcatctcttc ttcatcaatc acaacataat
      541 tatttggtaa tacaagttcc atttattttc tcctttttta ttaagcatgg ttaggatggt
      601 ttcataacaa gtgatcgcag gctttgttta gttacctaaa ttagacttcc ttcctttatc
      661 ttattttaaa tatttaaaac cagttactgc ttgaagctta acagtttact taattcaaat
      721 aacagctaat cactgattcc ctgattttat caaatatact aataacaaca attgtgatac
      781 gatcatcatt ataagaacaa catttaacga atcaaagttt ttccgagata ataataaagc
      841 aacagcaagc agtattatta ctaaagattg aataactact attactctta acattttatc
      901 ctccactaac aactcaagct cccttacatt atatcgacca gccccatgga aagattatag
      961 ctagactaat caatgatata atacatacta gaatacaaaa tattttttta ttcatacttt
     1021 ttctcctatc tttattttct acctacatag tacctcttat taagctcatt tcaaaattac
     1081 gttaactttt ttcacgaaaa ggagaaaatt atgcgttatg attatggata gcgctttcaa
     1141 atttttaaac tcctatccca tccttttatc tatattatga gcgaaaatat aataactgtc
     1201 aagtaactaa agtgaatttt ataaaaaaat tacaagccaa atttgtaaag tttacactaa
     1261 gccgctaggg caatcgtcta tcagaatgtc cgtttatttg tcaataatcc gagaaaatct
     1321 tgcaacgctt agaagtctat aaaaactatc aacatttata tgacttgcga atagcaatcc
     1381 tgctcaacct ttccacactc tatctataca atcaagataa aaacatgtgt aagcaaatct
     1441 gctacacttt actagaggac gccaagaata agaaaagcta cgataggctg gctatctgct
     1501 atgtccgtat tgggatttgt acagacgatt ctaaacttat ccaaaaaggg ttctcccttc
     1561 tggagctaac cgaggaaact tctatgctgt ctcatctcaa aaaagaagta gaaacctatt
     1621 atcaaccgaa ggaaagataa aaaagccgag ggatttcctc gactctttac atattatttg
     1681 ttcgttagtt cttaatacca gccattgtta aaccagaagt ttttagctct gccaagccac
     1741 atagtgtgtt tactactatg tgtccatgtc accatgaatc gccgaacgat ttaacgagaa
     1801 agtatgactt ttacgtttat cccaactcaa ttatgacatt tttttcaaaa gtcaatatat
     1861 ctcacttttt caacgacaag aaagaggctg ataatctacc aacctcttgt ttttaaatac
     1921 atttcaagtc caaactattc tttatagaaa aaagtcctat aaattcgagc aatagttaaa
     1981 atacaaacaa atataattcc caaaatagat aacactattt tcacaaaatt catttcagaa
     2041 cctattatat atacgtgaaa aaaaggggct attcctacac atatatacaa taaataactt
     2101 acaaagttta tttcaccaat tcctgcaaaa aaatgtttca ttttaagcaa aaatataacc
     2161 atctaagcta ccgtcagccc aatcagcccc atatgcgatt gctccaccta gtgaaaatcc
     2221 agtaacagtt agtgcaacgt ttagtgcagt attgactaaa tggccagctg cactacctac
     2281 atgtttaatt attaaactac gtaatgttct cgtaatagcc cctctattag ctgagatagc
     2341 tttttttatc gcataagcag aataaattgt tgcaccacca ctatagatgg ccaaacctac
     2401 atccagaact gttgcaaaac tacctctact attccaccag ttacgaccaa caccaccccc
     2461 atcaagatac atcatctctt cttgctcaag agcaacataa ttatttggta atacgagttc
     2521 catttatttt ctcctttttt attaagcatg gttaggatag tttcctaaca agtgagcatc
     2581 gactttgttt atagcactta gttacctaga taagatatct tccctttatc ttactttatt
     2641 ttataggtga cttaatgttt aaaaccaatt attgcttgaa acttaacatt tccaaaatcc
     2701 aatcaagata ggtttcttta tcatagacaa tctgcacttc aactggcata tccttttgga
     2761 gtatgaccgt ctcgcttcca tgttttagag ttaaggtttc taattctatc atgactttat
     2821 agaggctaat attcccctct ttcgtttctt gggaaattgt tcctgaatca atctgtctga
     2881 cttgtccctt tagtgttcca tatttttgac tatttacacc agtaatagca acatcaactt
     2941 ttgctccttt tgagacacga gaaatatcac tcgcaagtac aaaagcctct acatagtaac
     3001 ctttttcttt ccctgaaact tctgctatcg tttgcccctg ctgaatagac attccttgtt
     3061 tcaaaggtac cagataatgc agagtacctt catttgacgc taatatacta tgagctttat
     3121 cttgacctgt tgccactcca agattagcct caagctctgt aatactttta ttgttgtttg
     3181 aacgagcagt acctaactca ctaattaatt gagcataaat attataagcc tgagaagttg
     3241 gatcattata ggtacggttc atatccttaa tattgctttg ttgactatca atctcgctat
     3301 tcttagaagt aatatttgtt tttaatgctt cgatttttgt tgttatttct gatatcttag
     3361 tttctaactt agctttatca tcatctgatg tcgtatctga taaggaggat gagtctcctt
     3421 gctgttgaag ttgaatcaat tcattttgta gagtttgcaa gtcggcatct aactgatttc
     3481 tttcagctgt tattttattc aacttcgtat attcatcctg aatctttgaa tactgggtac
     3541 cattattata attttccgag tttaactgag acagatagta ttcaactttc ccataatatt
     3601 cctgttcttc accagaatta gataaatgat tgtatttctc atttaatgat tgttcaaatt
     3661 tttgaaagat agcttctttt gcacgtaact tctccaattg tttatttaaa gagctcgctt
     3721 gtaaaccttc ttgtccactt gataacgaaa taatgacatc tccagcattt accatatctc
     3781 cttctgactt atgtaaagta actaccttcc ctgaaccaat tgctgatagg aactctgtac
     3841 ctgttataac tgaatttcca ttcgctttta caatatagtt tttgggtata taagctgcgc
     3901 caaccaatgc accgcttaag ataatagcag ttgaaataat gagaataaac gcaaaagctg
     3961 gtggtctctt atcaaagaaa atacgagaat aacgtaattc tgatttatta tataatttca
     4021 taggcttaca attggtctaa aaatatctac taccattttt tcaggagaag aattaacata
     4081 aactgtatag acaatcccat ccgtttgaat atcattttca tagacatata gatccaattt
     4141 agaatacgca tactgtagat actctggact gtcttcaaaa cgaacatata aacaatacgg
     4201 aacagagata gaatcctgta catcataaat gttactgtac tgttgagcat tatgagcttg
     4261 aatataaaac tcaaaatcag tcgttattaa tccatcatca tgaatagtag taccacaact
     4321 ttttacaatt aatggaccaa aaatttgtgc ttttaacaac tgcaaatgtt gatgaaatct
     4381 attaatttcc tgatctacat cttctacttt tgtatcatgt aactttttac agataactga
     4441 ctttagtacc agttttttat tatcttttac ctctaactta gccataagta acctcctctg
     4501 tatctaacac agcctgtgac tgaatttgtt gattcacttg aacgctctgc aaaccaacca
     4561 ttctagcata ctttccattt ttcgccatta gttcttcatg agtcccatat tccacaatag
     4621 tcccattttc taaaaagcat atcttatcac atcgaagaat tgtagacagc ctgtgggcta
     4681 ctacaattgt tgtcttatcc attattttat taaagattaa atcctgaata atctgttcac
     4741 taaatgaatc taagttagag gttgcctcat caaatatata caaatcagct ttactcagta
     4801 gtgctcttgc aatagccaat cgttgtttct ctccacccga gaaattttga ccgccttctt
     4861 ctacaaagga gccataacga ttttgaaggc gttgaatcgt atcatgaata ccaacaatac
     4921 gacaaactct caccatatcc tcatatgtaa cagaaggatt accaattttt agattatcaa
     4981 taattgtccc tgtaaagagt tctatggtct gaggaatgta ggaaattttc ttacgtagtt
     5041 taccatagtc aagatctgat aagtcatttt ctcctatacg aattttcccc tcactcggat
     5101 ttataaatct taataacaaa cgaactagcg tactttttcc tgctccgctt tctccaacaa
     5161 aagctatttt ttctccttgt ttaattcgca aattaaagtc cttgataaca ggagggcgtg
     5221 aaccataggc aaatgttaca tctttaaatt caatgtcatc acataaggtg aagtctctaa
     5281 tactataatc caaggcaatg tcttcacgat ctacttccat caattcttga agccgactaa
     5341 ccgcaacctg tacctcttga aaggttaact gcaagccaac taaattctga ataggttctg
     5401 taaaatattg acttaatgtc tgaaaaacca agaggtcccc aatagtcatt tttccatcaa
     5461 tgataaataa ggcgcccact cccataaata ataacccacc catggttgag gtcattgaag
     5521 atattgtaga ttgaatattc tgcaaaacac cctctttata accaatttct aaagtatgaa
     5581 caaatttttc ttcaattttg tttaaacgtt gttcctcatc atgctgagac ttaatggtat
     5641 caatgttacg aatagattca attaactgtg aattaagaag tccatttgct tccatttgtt
     5701 catgattaat ttttttataa ggctttttaa aacagtatat aagaatgatg ttaacaataa
     5761 ccataaaaac taatatcaga aataaagatt gattaatagt ccaaaggaca accgcactaa
     5821 taactgacaa ggtgatatcc atgactaatg aaatagagac tgacgtaaac acattcttta
     5881 tcgtcatcgc atcttgaaat cttgttaaaa catcaccaac tctacgactt ccaaaaaaac
     5941 tataaggaag atgaataata tggtcataat atcccattaa aaccggtata tcaatttttc
     6001 gagatagaaa caaaagaacg tgctgacgaa atgcagatag aagagtctgt aagaacgaca
     6061 ctattccaaa tactatcaaa aacatataca gactattttt taaagcatat ggaatcacct
     6121 cgtccatgat aacttttgaa aagagactcg ataaaatacc aatgatactt aaaacaaagg
     6181 aagctaatat gactgtacta atcaatcctt tttgattaaa aattaacctt ccaaataaat
     6241 caagaagtcc ttttcccttt agtttccctc tttcaaaatc cgaatttgga accataaaaa
     6301 gagtaatacc ttgataaatt tctcccagtt cgtcacttga catcttgcgt atgccactag
     6361 cagggtctgc tacgtagaac ttactattcc ttttgatact atgtagtacc acaaaatgat
     6421 tttgacctaa atcattctta acttgaagaa tcgcaggaaa tgttaatttt ggagtcaaat
     6481 cttccagtgc tactcgaaca gcttttactg taaaattcaa cttattcaga cctgaaacaa
     6541 taccactgac agtcgttcca tacatgtctg taccaataat ttccctaatc ttcatgattg
     6601 atagttcctt tttgtaagat aaaagaactg ttgaaacaac tgccgcagca caatctgact
     6661 ggtcatgttg catcgtacaa ggatattttt ttaacataga aatactcaat tctttagaat
     6721 taatctaact tttctttgat gtcacccaaa cctcaatcac tgcccagtag ttcttgaatt
     6781 aatttatttt caaccgtatc attctttgtt cttgatatct ttccaagcat tgtagtacag
     6841 cagatttttg cccaaggact gagcctcctt taacaactca aactccctta cattatatcg
     6901 gccagcccca tagaaagatt atagccagac taatcaatga tataatacat actagaatac
     6961 aaaatatttt tttattcata ctttttctcc tatctttatt ttctacctac atagtacctc
     7021 ttattaagct cattttaaaa ttacgttaac ttttttcaca aatttatttc gactttcttt
     7081 tttacttttt acattgctat gatacaatat ttttaacaaa attttattgt ttgttaactt
     7141 ttttcacgaa aaggagaaaa tcatgcgtta tgatttcgga aaggtctata aagaaatacg
     7201 tgagtcaaag gggctgaccc aagaagaggt ctgtgggggt gttctctcaa gaaccagctt
     7261 atcaaaaatc gaaagtggca agacaacccc aaaatatgaa aatatggaat ttcttctccg
     7321 tcaaatcaat atgagttttg aagagtttga atatatctgt caactttatc aaccaagtca
     7381 acgcacagag attatgcaaa cctatctcaa tatgcgttcc attatcggga ccagcgatct
     7441 tgtcaattta tttcaaaaat gccaagacta cctcaagacc caccacgatc tccctataga
     7501 agaaatcaga gatatgcttg aagttgttat ttatctccgt caacacgggg caggggaact
     7561 atcaaaacac gcagaacagg ttgtcaaaaa actttggaaa aaaattgaaa aacaagatac
     7621 atggtatgag agtgatctaa aaatcctcaa taccattctt ttcagttttc ccattgaata
     7681 cctccatctc atcactggaa aaatattgca acgcctagaa gtctataaaa actatcaaca
     7741 tttatatgac ttgcgaatga caattctatt aaacctttcc acactctatc tatacaatca
     7801 agataaaaac atgtgtaagc aaatctgcta tactttactg gaggacgcca agaataagaa
     7861 aagctacgat aggctggcta tctgctatgt ccgtattggg atttgtaggg atgatgcgaa
     7921 acttatccaa aaagggttct cccttctgga gctaaccgag gaaacttcta tactgtctca
     7981 tctcaaaaaa gaagtagaga tctattacca agcgaaggaa agataaaaaa gccgagggat
     8041 ttcctcgact ctttacatat tatttgttcg ttagttctta ataccagcca ttgttaagcc
     8101 agaagttttt agcagcagtc catgaaccgt aacgtcctgc aacgtaggca tctgctacac
     8161 gttcttggtt ttcagctgag tagtcaccgt tcaggtatga atctgttaat tggtaacgtc
     8221 cgatataacg tccatttgta gctgtatagc taccacctga ttctttttga gcgatccatt
     8281 ctttggcttc tgcttcagat ccgcttacag ttgaaacaac tgtttcactt actactggag
     8341 tttctgctac tggagctgaa acagtttcat cttgagcggc tggtgccgca taagtagctg
     8401 gcgctggtgt tgcaacaggc gctacagggc catcgataac caactcttga tcaacataaa
     8461 tcaaatgaat gttatcaatg tggttgtttt ctgccaattt ttcaactgtt gtgttgtgag
     8521 tttcagcgat ttctgaaagt gtatcacctt ctttaacagt gtaagttgat gattcttgag
     8581 cagatacaaa tgatggagca aatactgcaa acaaggcagc tactcctgca agagttgctt
     8641 taatcttttt agttattgat ttcatattcg aaaattctcc ttctttctat agttctatca
     8701 taccctttaa atattaccgt ttcttgacac ttttatgtag aaatattaca aaattatttt
     8761 ttatttccct aaataaggtg ttttttgtca taaaagatac tatttttatg ctatttgagg
     8821 tattagaaag gttttcatcc acaattaaag ccaagcccct cattctttga tataatagag
     8881 ataagaattt ttataagggg aaactgatga aatcacttcg ttttcaatct gtctttgata
     8941 tcatcggacc agttatgatt ggcccatcta gtagccatac cgctggtgct gttcgtattg
     9001 ggaagattgt ctcttccatt tttgatgata ctccgacaga agttgaattc caacttttta
     9061 actcatttgc caagacctat cgtggtcacg gaacagacct agcccttgtt gcaggtattt
     9121 taggaatgga tacagatgat cctgaaattc caaatagtct ggaaattgcc cacaagcgtg
     9181 gtatcaagat tgtctggacc attcagaaag acagcaatgc ccctcaccct aacaccacta
     9241 aaattactgt taaaaatgcc cacaagacca tcagcgtgac tggtatttct atcggtggag
     9301 gaaatattca ggtaaccgaa ctcaatggtt ttgccgtctc tctcaatatg aatacaccga
     9361 ctatcatcat cgttcatcaa gatattccag gtatgattgc ccttgttaca gaggcgcttt
     9421 cccgctatgg tatcaatatc gcccagatga atgtcactcg tgaaaaagct ggtgaaaaag
     9481 ccattatgat tatcgaagtt gacagtcgca actgtgatga ggctatcgaa gaaattcgaa
     9541 aaatccctca tctccacaat gtcaatttct ttaaatagga ggaagcatgt tttattctat
     9601 caaagaattg gtcgagcaag cagatctgga ctttcaagga aatgtcgcag aactcatgat
     9661 tacaacagag tttgaattga ccggtcgcga acgtgaagaa gtcttccttc tcatggaacg
     9721 caatctggaa gttatgaaag cctctgtcca acttggcctc aatgaaaata aatctcgtag
     9781 tggcctgaca ggtggagatg ctgccaaatt ggatcactac atcgaaaacg gaaaaactct
     9841 gtcagattat acgattctct cggctgcccg aaatgccatc gcagtcaatg aacacaatgc
     9901 caaaatgggc ttggtctgtg ccactccaac cgctggaagt gctggctgtc tgccatccgt
     9961 tctcactgct gctattgaaa aattagacct cagccacgag caacaattgg atttcctctt
    10021 tgctgctggt gcctttggac tagtcatcgc aaacaatgcc tccatctcag gtgctgaggg
    10081 tgggtgtcaa gctgaagttg gttcagcctc tgctatgagt gctgccgcct tgactctggc
    10141 tgcaggtgga acaccttatc aggccagtca agctattgcc tttgtcatta aaaatatgct
    10201 aggcctcatc tgtgaccctg ttgcaggttt ggtcgaagtt ccctgtgtca aacgtaatgc
    10261 catgggagct agctttgctt tcatcgcagc agacatggcc ttggcaggta tcgaatctaa
    10321 aatccctgtg gatgaagtga tcgatgccat gtaccaagta ggagcaagca tgccaactgc
    10381 ctttcgtgaa acagctgaag gtggactcgc taccacccct actggtcgtc gcctccaaaa
    10441 agaaattttc ggagaataag cttatcaaat aggagaaacc atgacctcta tcacagcgat
    10501 ttttttcgat ttggatggaa ccctcgttga tagttctatc gggattcaca atgcctttac
    10561 ctataccttt aaagagctgg gggtgcctag ccctgatgcc aaaactattc gtggttttat
    10621 gggaccacct ctcgaaagta gttttgcgac ctgcctgtcc aaagaccaaa tttctgaagc
    10681 cttgcagata tatcgttctt actataaggc aaaaggcatc tatgaagctc aactctttcc
    10741 tcagattata gacttgcttg aggagttatc gagcagttat ccactctaca tcaccacgac
    10801 aaaggataca tctactgctc aagacatggc aaaaaacttg gaaatccatc atttctttga
    10861 tggcatttat ggttctagcc ctgaagcacc ccataaggca gatgtcattc accaagcctt
    10921 gcagacacat caactagcac cagaacaagc catcatcatc ggagatacca agtttgatat
    10981 gctgggagct cgagaaacag gtattcagaa attggccatc acttggggat ttggagagca
    11041 agcagatcta ctaaactatc aacctgatta tatcgctcac aaacccttag aagttttggc
    11101 gtattttcaa tagcatagac tgggtaacaa ttccatttca gaagaaaatg aagtaatact
    11161 caatgaaaat caaagagcaa actaggaaac tagctgcggg cagctcaaaa cactgtttta
    11221 aggttgtgga tagaactgac gaagtcagct caaaacactg ttttgaggtt gtggatagaa
    11281 ctgacgaagt cagtaaccat atacggcaag gcgacgttga cgtggtttga agagattttc
    11341 gaagagtata agtctctaca taataaaacg catattacca aggttgttaa cttgataata
    11401 tgcgtttttc ttttttattc aatgtgggtt gtttgattag caaaggcgat aatagcttgc
    11461 ttcaactcat ctccactgag agtgcggaac tctccaatct tttgattgat ggattctaaa
    11521 ggcatgacat taaccttacc aacgaaaatc ttatccataa cttgattatc aacgagttcg
    11581 gttgatacca agagttcttc gtagagtttt tcacctgggc ggattccaac ttcaacgatt
    11641 ggaatttcac tttcagtgtg gccacttaga agcaccatct tcttggccaa gtcataaatc
    11701 ttgactggtt tgcccatatc aaggataaag acttccccat ctttggcata agcaccagca
    11761 tggataacca gacggctagc ttctggaatg gtcataaagt aacgggtcat gcggaagtct
    11821 gtcaccgtta caggcccacc ttcagcaatc tgacgttcaa agactggaat gacactacca
    11881 cggctaccaa gaacattccc aaaacgaact gcacagtagg ttgattggct acgttggtta
    11941 aagccagtga caatcaactc cgccacgcgc ttggttgctc ccataacatt tggtggattg
    12001 actgccttat ctgtcgaaat cataaccatc ttagacactt tagcttcatc aacagcctta
    12061 gcaacattgt aagttccacg gatattgttt ttgaaggctt cttttggatt gcgctccatc
    12121 ataggaacat gcttgtgggc tgccgcatga taaacaatag caggtttgta ctgctcaaag
    12181 acttgcaaca aacgatcata gtcttgaatg tccgcaatca caggtacata atcaatccct
    12241 tggaacttac gaatcaattc atgataaaca aggtagattg agttttcccc atgaccgagc
    12301 aagacaatgc attcaggatt gaagcgacta acttgacgac agatttcaga accgattgaa
    12361 cctccagctc ctgtgactaa gatggtctta cctgtcagtt ctgcacccag acgcgattcg
    12421 tcaagacgga tttcctgacg acctaaaagg tccgtaatat caattttttg gaagccagta
    12481 cctgcttggt gaaggccctg aacaacagtt tcaaccttag gcatcttgta acatttgaca
    12541 cccagcttat tacacatctg caagatacgc tcatattctg acggatccaa cgacggaatc
    12601 gcaacgatga cacgctcgat ttgatggcgt ttggctaatt caggcagatt gtcataagag
    12661 cccaaaacag gaataccacc aagtttttga ccctttttct tagaatcctt atccaaaata
    12721 ccgaccagtt ctaattcact ggttggatgt tggtaactat ccataaagag agccccacca
    12781 tcaccggcac caatcaagaa ggtccgacgg tgttctccat caccactacc ttttttgcgt
    12841 ctggagtaga ttaactgcca agtaatccgt ggcaataaaa tcaagaaggt actcaacaag
    12901 ataaagagaa tgataaaacg gatggagaag agtggcaaga aggcataaca gatactatat
    12961 gacaagacac tgctagcagt cacaccaaaa aagattttca tgaaatccgt aatcttgctg
    13021 taacgactaa tgctcgcgtt caacccccaa aaaccaatca tcaattgata gaacaggaag
    13081 gccaaactcg tatagataat gtagtcaaca ggtgctggat taatcagccc ataaaataaa
    13141 atataagata caatgatgga aaccaccata ctgaaaatat caaatattcc ccagaaaacc
    13201 tgcttttgtt gtttatttaa aatttccacc agatcaatca cataatctgt tagtttttta
    13261 ttcatagaaa tctactcctc cttaaaagag ttttactata ttgttattat agcatatttt
    13321 tatttatttg gcttatttta tctaaataaa ttattgttct cttgtactcc ttcttccatt
    13381 taaatcctct aattaaacct acaatcgtcc caaagccata agcaaagtga atggaaaata
    13441 aaagaaaggg catcacaatt agaaatccat ttttatgttt taataaagtc agcaaagtga
    13501 gtagtgacaa aagtagaaaa taggcaccta atagtaaagt tatgaatacg aatgtgatcg
    13561 gtaacaatgc tagactaaac acaagactca aaacaaataa acaaggaaca tagtgaaata
    13621 atgataaaca cttaaactga acatgacttg tcaagccaat ccacaaacca tttaaatact
    13681 tttgatgcag cattttcttg aatgttggtc gaatatactg ataagataga atacttgggc
    13741 tatagcggat tttataacca tgttctcgaa ttctataatg aatatcatta tcttcagttc
    13801 ggccaagttg ctcatttact aaaccaactt tctggaaaac ctctcgttta tacatcccat
    13861 gaaaaataga agaaacatat ctatcctcgg aactatttcg ataattggca atactactgc
    13921 caaacatatt ttcctcaaca agatgcaagg tctctgccca ttttcctttt ccttcgacaa
    13981 tcgtcggtct aggcccccca cagacaaatt caccttgttg aataatagcc acattgttca
    14041 ttacaaaagt ctcagtaact tttgaatgag catcaatttt taaaataagg tcccctacag
    14101 aatgtttaac tcccaggtta aaaccactag cttgattttt cttaggattg ttatacaatc
    14161 taattgagtt aaactctgta tcttccttta taaattgctg aatgatagct gtggtcccat
    14221 ctgtggatat agcatttata aatagaattt caatattctc tttaggataa gtttgatttt
    14281 ttaagtcttc aattagacca ggcagatatt tttcttcatt gtatgcactg attacaatgg
    14341 atacgagaag actttcaaca ttttgagtca ctactactct cctgaatttt tccttccacc
    14401 attctatcat aattttcaag a
//
LOCUS       DAVLTT010000046        14049 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLTT010000046 DAVLTT010000000
VERSION     DAVLTT010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14049
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.046"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            83..880
                     /locus_tag="VYN15_001555"
     CDS             83..880
                     /locus_tag="VYN15_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV1452857.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVGMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLLGLPYAFLNKNEDTYVD"
     gene            1028..1150
                     /locus_tag="VYN15_001556"
     CDS             1028..1150
                     /locus_tag="VYN15_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEV1452858.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTSFIFDDT"
     gene            1172..2212
                     /locus_tag="VYN15_001557"
     CDS             1172..2212
                     /locus_tag="VYN15_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV1452859.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETFG
                     NPLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGVIVDSGRFDWAASGKFPQFVEEDPSYHNLSYTRDVGAAAFIIAVRVQLLCDTGA
                     ALSPFNAFLLLQGLETLSLRVERHVQNAEKIVDFLVKHPKVEKVNYPKLADSLYHALA
                     EKYLPKGVGSIFTFHVKGGEAEARKVIDHLEIFSDLANVADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            2383..3657
                     /locus_tag="VYN15_001558"
     CDS             2383..3657
                     /locus_tag="VYN15_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV1452860.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VYN15_001559"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VYN15_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV1452861.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHHLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4787..5089
                     /locus_tag="VYN15_001560"
     CDS             4787..5089
                     /locus_tag="VYN15_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1452862.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVINFGLWIAKAPSQERGRLAFLQILAQTLQGFR"
     gene            5197..5835
                     /gene="udk"
                     /locus_tag="VYN15_001561"
     CDS             5197..5835
                     /gene="udk"
                     /locus_tag="VYN15_001561"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV1452863.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5963..7303
                     /locus_tag="VYN15_001562"
     CDS             5963..7303
                     /locus_tag="VYN15_001562"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV1452864.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7281..7493
                     /locus_tag="VYN15_001563"
     CDS             7281..7493
                     /locus_tag="VYN15_001563"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV1452865.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7490..8365
                     /locus_tag="VYN15_001564"
     CDS             7490..8365
                     /locus_tag="VYN15_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV1452866.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQIPFE
                     TESIVSVVESLRING"
     gene            8358..9173
                     /locus_tag="VYN15_001565"
     CDS             8358..9173
                     /locus_tag="VYN15_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV1452867.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9166..9597
                     /locus_tag="VYN15_001566"
     CDS             9166..9597
                     /locus_tag="VYN15_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1452868.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9604..11271
                     /gene="recN"
                     /locus_tag="VYN15_001567"
     CDS             9604..11271
                     /gene="recN"
                     /locus_tag="VYN15_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV1452869.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11273..12001
                     /locus_tag="VYN15_001568"
     CDS             11273..12001
                     /locus_tag="VYN15_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV1452870.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDYPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12080..13903
                     /gene="lepA"
                     /locus_tag="VYN15_001569"
     CDS             12080..13903
                     /gene="lepA"
                     /locus_tag="VYN15_001569"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV1452871.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT         4151 a         2558 c         3357 g         3983 t
ORIGIN      
        1 acttttatga aatatagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gggatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgctgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat aatatggagg
     1021 tcaccttatg acttgtgatt ttaaatttga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatctt ttatttttga
     1141 tgacacgtag gaaggtgctg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaataca aagcttgtct tgattgaaac ctttggtaac cccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaaca ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattggt ggagtgattg tcgatagtgg
     1681 tcgttttgac tgggcggctt caggtaaatt ccctcaattt gttgaggaag atccgagcta
     1741 ccacaacttg agctatactc gtgatgtggg tgctgcagcc tttattatcg ctgttcgtgt
     1801 ccaattgctt tgtgatacag gtgcggcctt gtccccattt aatgcattct tgttattaca
     1861 aggacttgag accctctctc ttcgtgtgga acgccatgtg caaaatgctg agaaaattgt
     1921 tgatttcctt gtcaagcatc ctaaggtaga aaaagtaaat tatccaaaac ttgcagatag
     1981 tctttatcat gccttggctg agaaatactt gccaaaaggt gtgggttcaa tctttacctt
     2041 ccatgtcaaa ggtggggagg cagaagcacg aaaggtaatt gatcatttag aaatcttttc
     2101 tgaccttgca aatgtggcag atgctaaatc gcttgtggtc catccagcaa caaccactca
     2161 tggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatt aaatccactt
     2221 gtctatcgga cttgaaaatg tagatgattt gattgaagac ttgcgcttgg ccttggaaaa
     2281 aatttaaaga aaaagaagat aaacagtggt tttcgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaacg atatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gagagtcagt atgccgaact cttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaagcagga actggccttg
     2521 gctgagcaaa aggccatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagaa
     2641 gttgaacaga caagccatca ggctctcttg gctaaggaca aggaagtaca ggctttggag
     2701 aaccaattgg ccactttgcg tttggagcat gaaaatcaat tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgtaatca ggtcaaaaat cagctcctac tgcaagaaaa ggaaaatgag
     2821 ttgtctttgg cttctgttaa gcaaaactac gaagcccagc tcaaagcagc cagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat taacttaaaa aaggaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaatcactc tgggctattc cacgacgact
     3901 gaggatgcta gtggggaagt ggtcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta ctcagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctctta ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcatttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcctgat aaaaccccat actaaatagt agaatggttt
     4621 tgggaattat aatattccaa ttgttgcgag ttgtaggtac tcaaataatc tatatagaaa
     4681 tttagaggtg tgaaatgaag caatttaaaa ttctttcaga taaatattta gagtccatta
     4741 caggttctgg tgggaactta ggcccaggat ttggtgtgat aattctatga tgcgaaatga
     4801 gtttcgagaa agggtggagc aacttcttca acaaaaagaa ataaatgaaa atagtgagtt
     4861 gagtcacctg tttcgtcttg ctatacaaaa tttagacaga aatgaaaaat accaaacggt
     4921 catggccaat ttgagtcaag ggttgtcact ttacctcatg acgcatcatt accaggcacc
     4981 taagtctgtc attaattttg gtttatggat tgccaaagct cctagccagg aaagagggag
     5041 actggctttc ttgcagatac ttgctcaaac cctacagggc tttcgttaaa actgtcgaac
     5101 atcagaggga agactctggt gttttttgct gatgagacta taaattttgt aaaaaatgtg
     5161 atagaataga cgacggataa aataacggag gatagcatgc aaaatagacc aatcattatt
     5221 ggagtgacag gtggttctgg tggtggtaaa accagtgttt caagagccat tttatcgcat
     5281 tttcctgatg aaaagatttc catgattgag catgattcat actacaagga tcagtctcat
     5341 ttgacctttg aagagcgtgt caaaaccaac tatgaccatc cttttgcctt tgatacagac
     5401 ttgatgatcg agcagattaa ggaattgttg gcagggcgtc cggtggacat cccgacctac
     5461 gactatacag agcatacacg gagtagcaag acctatcgtc aggagcctca agatgtcttt
     5521 atcgttgagg gcattttggt cttggaggac aagcgtctgc gcgatttgat ggatatcaag
     5581 atttttgtgg atacggatga cgatgtgcgc attattcgtc gtatcaagcg tgatatggag
     5641 gagcgtggcc gtagccttga tagcgttatt aaccagtact taggtgtggt caaaccaatg
     5701 taccaccagt ttatcgagtc aactaagcgt tatgctgata tcgtcattcc tgaaggggtt
     5761 agcaataccg tggctatcga cctgttgacg accaagattg caaagatttt ggaagaagct
     5821 cgaaacagca aataatcaca tgtggaggcc ttgcctcctt tttctatttt tccctcataa
     5881 tggtacataa atggagattt ttaggcatat ttttggtata ataataccca tgaaagagca
     5941 agtaaatgaa tagtaggtgg agatggaaaa gtatttatcg gtaacaactt tgaccaagta
     6001 tctgaaaatg aaattcgata aagacccata cttggaacgg gtctatttaa ctggtcaagt
     6061 ttccaacttt cgtaaacgac ctactcacca atatttctcc ctaaaggatg accatgcagt
     6121 tattcaagcg accatctggt ctgggattta tcagaaatta gggtttgacc tagaagaagg
     6181 aatgaagatc aatgtgattg ggcgtgtaca ggtctatgaa ccaagtggta gctactccat
     6241 catcattgaa aaagctgagc ctgatggggt tggggcgctt gcgattcagt ttgaacaact
     6301 taagaaaaaa ttgacagaag aaggcctgtt tcaagaacgc ttcaagcaag ctctacccca
     6361 attttctaag agaattgggg tagtaaccag ccgtagtgga gccgttattc gagatattat
     6421 cacgaccgtc agcaggcgat tcccaggtgt tgacatcctt ctttatccga ccaaggttca
     6481 aggtgaaggg gctgcggagg aaattgcaag aaatattgcg cgtgctaatc aacgggacga
     6541 tttggatttg ctcattattg gtcgtggagg tggttctatt gaggatctct gggcctttaa
     6601 cgaagaaatt gtggtacgag ctatttttga atctcgtttg ccagttatct ctagtgtggg
     6661 gcatgagacg gatgtgacct tggcagattt tgtggcagat cgacgcgctg caacgccaac
     6721 agcggcggct gaactggcaa cacctgtgac caagttggat gtattaactc atttgcaaaa
     6781 tcaggaaaaa cggatggcaa cggcagtccg aaatgttcta tctaagaaac aagaggcttt
     6841 gaaaaaatgc agtcagtctg ttatctttag acaacctgag cgcttgtatg acggttattt
     6901 gcaacgcttg gaccaactgc aactgcgttt gaaacaaagt ttgcgaactc ggatttctga
     6961 taacaaacaa ttagttcaag caagaactca tcaattagta caattatcac ctgttaccaa
     7021 aatccaacgc tatcaagacc gtttaggaca gttggacaag ctcttaggta gccaaatggc
     7081 gttagtttat gacgccaagg ttgctgaggc caagcgactt tcggaagctt tgctcatgtt
     7141 ggatactagc cgaatcgtgg cgcgtggtta tgctattgtc aaaaaagaag agtccgttgt
     7201 agattcggtt gagagtttga agaaaaaaga ccaagtaacg cttttgatgc gagatggtca
     7261 agtagaatta gaggttaaag atgtcaaaac aaaagaaatt tgaggaaaat ctagcagaac
     7321 tggaaaccat tgtccaaagt ttggaaaatg gtgaaattgc tctggaagat gcgattactg
     7381 cctttcaaaa gggcatggtc ttgtcaaaag agctccaagc tacgctggac aaggctgaaa
     7441 agaccttggt caaggtcatg caagaagacg gaacagaaag tgattttgaa tgaaaaagca
     7501 agaaaaatta gctcttgtcg agtcggcttt ggaagatttt tatggagacc agcagtttgc
     7561 ctctagttta cgggagtctg ttctctattc tattcatgct ggtggcaagc gtattcggcc
     7621 ttttctattg ttagaagttc tggaagcctt gcaggttacc atcaaacctg ctcacgcgca
     7681 ggtagctact gccttggaga tgattcatac agggagcttg attcacgatg accttcctgc
     7741 tatggatgat gacgattatc gaagagggcg gttaaccaat cacaagaaat tcggtgaagc
     7801 tatggccatt ttggctggag atgccttatt cttagaccca tatgccttga ttgcgcaggc
     7861 agatttgcca agtcagatca aggtggactt gattgccaac ttatcccttg cttcaggtag
     7921 tctgggtatg gtggcagggc aagttttgga tatggagggc gaacaccagc acttgtcttt
     7981 ggaagaactt cagactattc atgccaataa gactgggaag ttactagcct atcccttcca
     8041 agcggcagct attatagctg aattgtcacc tgaaatgcag gtgaagctga aaactgtggg
     8101 tgaattgatt ggacttgctt ttcaagtcag agatgatgta ctggatgtga cagctagttt
     8161 tgaggaaatc ggcaagacac ctcaaaagga tctgcaggca gaaaaatcaa cctatcctgc
     8221 cctgttgggc ttggaagagt ccattgcctt ttgtaaccaa accctggatc aagctaatga
     8281 aaaattagaa gaaattgccc agcagattcc ctttgaaaca gaatcgattg taagtgtagt
     8341 agaaagtttg agaatcaatg gctaaggaaa gagtggatgt actagcttat aaacaggggt
     8401 tgtttgaaac gagagagcag gccaagcgag gtgtgatggc tggcctagtc gtagcagtcc
     8461 ttaatggaga acggtttgac aagccaggag agaaaattcc agatgacacc gaattaaaac
     8521 tcaaggggga gaaactcaag tatgtcagcc gtggtggttt gaaactggaa aaggccttgc
     8581 aggtctttga tttgtcggtg gatggcgcga ctacgattga tatcggggcc tctactggag
     8641 gttttaccga tgtcatgcta cagaatagtg ccaagttggt ctttgcagtc gatgttggta
     8701 ccaatcagtt ggcttggaaa ttacgccaag acccacgagt tgtcagtatg gagcagttca
     8761 atttccgcta tgctgaaaag actgatttcg agcaggagcc gagctttgcc agtattgatg
     8821 tgagtttcat ttcccttagt ctgattttgc cagccttgca ccgtgtcttg gctgatcaag
     8881 gtcaggtggt agcacttgtc aaacctcagt ttgaggcagg acgtgagcag attgggaaaa
     8941 atggaattat tcgagatgct aaggttcatc agaatgtcct tgaatctgta acagctatgg
     9001 cagtagaggt aggtttttca gtccttggct tggacttttc tcccatccaa ggtggacatg
     9061 gaaatattga atttttagcg tatttgaaaa aagaaaagtc agcaagcaat cagattcttg
     9121 ctgagattaa agaagcagta gagagggcgc atagtcaatt taaaaatgaa taaaaaagag
     9181 agacttgaaa aaattagaag attggtgaca gattatcaaa tcggcacgca agaagaaatt
     9241 gtagaacatt tgaaagaagc aggtatcact gccactcagg cgacggtatc ccgagatatc
     9301 aaagagttag gtattgtcaa aattcctttg agagacaaca cctatgtcta cgaattgcca
     9361 aaatcaatcg taaaaagtct gcaactggct gaagacaata tcgaatcggc tgaattgatg
     9421 gataagatga tcaatctcca agttattcca ggaaatacgg cttttgtaaa agctcagtta
     9481 atcgatactt ttgcagacaa gatttttagt tgtttgactg atgatagctc gattttagtc
     9541 attgccagaa gtggaagtct agcagaggaa atctttgaac aagtaaaaaa ttggtaggtc
     9601 tatatgttac ttgaaatttc gataaaaaac tttgccatta ttgaggctat ttccctcaat
     9661 tttgaaaagg ggatgactgt cctgactggt gaaacgggtg cagggaagtc gattatcatt
     9721 gatgccatga atatgatgtt gggagctcgt gcgacgacag atgttattcg tcatggtgca
     9781 ccaaaggcag agattgaggg gcttttctca gttgagaata gtcgtctttt acaggaaatt
     9841 tttgatgagc aaggtttaga gttaggtgat gaaattatca tccgtcggga aatcttgcaa
     9901 aatggtcgta gtatcagccg tgtaaatggt cagatggtta atctgtctgt tttgcgagct
     9961 attgggcaac atcttgtaga tattcatggt cagcatgacc atgaggagtt aatgcgtccc
    10021 caactgcata tccagatgtt ggatgaattt ggtgatgccg ctttttggga cttgaaagaa
    10081 acctatcaaa cgagttttga tgcctatcgg aaaatgcgca agcaggttct ggaagtcaag
    10141 aaaaaccaac aggaacacaa ggcacgtatc gaaatgttgg aatttcaaat ggcagagatt
    10201 gaggcagcaa acttgcaggc tggagaagac ttggatctca atcaagagcg agataaactc
    10261 ctcaaccaca aaaatattgc ggatacactg accaatgcct acagtatgtt ggacaatgaa
    10321 gatttttcaa gtctggccaa tgttcgttca gccatgaatg acatggaaag tgtcgaagag
    10381 tatgaccctg aataccgtga aatttcaagc tctctgtctg agacctacta tgttttagaa
    10441 gacattagca aacgtttgga agctatcatt gaggaccttg attttgatgg caatcgcctc
    10501 atgcaggttg agaatcgttt ggacctcctt catactatta ctcgtaagta tggtgggact
    10561 gttgatgatg ttttgcttta ttttgccaag attacggaag aatacaatct cttgacaggc
    10621 aataatcttt cgtctgagga catggaagca gagcttaaga agttggaagt caatcttgtc
    10681 aatttggcag gtcaacttgc ttctgctcgt cataatttgg ctcagcaact cgaagctgag
    10741 attaaacaag aactgcaaga tctttatatg gaaaaagccc agtttcaggt tcgttttagt
    10801 aagggaaaat tcagtcgtga gggaaatgaa atggttgagt tttatatttc aaccaaccct
    10861 ggagaagact ttaaaccctt ggttaaggtt gcttctggag gggaattatc tcgtctcatg
    10921 ttagccatta agtctgcctt ttcacgtaaa gaaggcaaga ctagcattgt ctttgatgag
    10981 gtggatacgg gagtttcagg tcgtgttgct caagctattg ctcagaaaat tcataaaatt
    11041 ggtcagtatg gtcaggtttt ggctatctcc catttgccac aagtaattgc gattgcagat
    11101 tatcaattct ttattgagaa gattagtaat gaccattcaa cggtttcgac tgttcgtctc
    11161 ttgacagtcg aagagcgagt ggaggaagtt gccaagatgt tggcaggtga tgatgtgaca
    11221 gaagcagccc tgacgcaagc cagagaattg ttgagaaaca gggagaaata agatgacaga
    11281 ttattatgta attggagatg ttcacggaaa agctgggatg ctggaagacc ttcttaaaac
    11341 ctgggatggt cagacccagt tgctctttct aggtgatttg attgacagag gtgaggatag
    11401 tcaccgtgtt cttgaaatgg tcaaggactt ggtggacaat caaggggcta tctgtttgtc
    11461 tggaaaccac gagtatatgt ttttgacttg gctagattac ccagaagaaa gttatgacca
    11521 ttatcgtcgc aatggtggag atacaaccat taactctatc ctaggtcgtc ccttggatgc
    11581 accagttgat ggagtagaag atgccaagcg ggttgccgct gaagcggcag acttggtcga
    11641 attcattcgt caaatgccat ttgtagtaga gacagacaag tatatctttg ttcacgcagg
    11701 tattgatttg accttggacg actggcatga aacaacagat tataaaaaag tatggcttag
    11761 aaaaccattc cacggagctg aaaatcatac tggaaaaacc attgtcttcg gtcatacacc
    11821 ggtctatggt ttgttacagc aagaacgcgg tacatctgag ctttggacta cagaagatgg
    11881 caagattgga atggatggag gagctgttta tggtggtgtc cttcacggga ttgtctttac
    11941 agaccaagga atgacagaac accactttat cgaaaatgac ggctttgtcg ctgaagatta
    12001 gtactcctag cagggtatgg tcttgtcaaa atatcaaaaa caatttataa taaatagata
    12061 ccctgaaagg aagagaatca tgaacttaga agaattgaaa aaacgacagg agaagatccg
    12121 taacttctct attatcgccc atattgacca cggaaaatca actctagcag accgcatttt
    12181 ggaaaaaaca gagacggttt caagtcgtga aatgcaggcc cagcttttgg atagcatgga
    12241 tctagagcgg gaacgtggaa ttactattaa gttgaatgcc atcgagttga attacactgc
    12301 aaaagatggg gaaacttata ttttccactt gattgacaca ccagggcacg ttgactttac
    12361 ctatgaagtt tcacgttcgc tagctgcctg tgagggtgct attttggtgg tcgatgcggc
    12421 tcaaggaatt gaggctcaaa ctcttgccaa cgtttatcta gctttggata atgatttgga
    12481 aatcatgcct atcattaata aaattgacct gccggctgca gatccggagc gcgtgcgtac
    12541 agagattgaa gatgtgattg gtttggatgc cagtgaagca gttttggctt ctgccaaggc
    12601 tggtattggg attgaagaaa tcctcgagca aattgtagaa aaagtaccag caccaacggg
    12661 tgatgtgacg gcgccactta aggccttgat tttcgactct gtttacgatg cttaccgtgg
    12721 ggttatccta caagtgcgtg tcatggacgg agtggtcaaa cctggtgata agattcagct
    12781 catgagcaat agtaagacct ttgatgtggc cgaagtcggt atttttacac caaaagcggt
    12841 tggtcgtgat ttccttgcga ctggtgatgt tggttacatt gcggcgtcta tcaagacggt
    12901 tcaggatact cgtgtgggtg ataccgttac cttggcaacc aatcctgcgg cagaaccatt
    12961 acatggttat aagcagatga atcctatggt ctttgcgggt ctctacccaa tcgaatcaaa
    13021 caagtacaat gacctgcgtg aagcgcttga aaaattgcaa ctgaatgatg ctagtcttca
    13081 gtttgaacca gaaacatctc aggcacttgg atttggtttc cgttgtggat ttcttggact
    13141 tctccatatg gatgttatcc aggaacgttt agagcgtgag ttcaatattg acctcatcat
    13201 gacagctccg tctgttattt acaaagttaa tttgaccgac ggtgagtcta tggatgtgtc
    13261 taacccatct gagtttccag acccaactaa gattgcgacc attgaagagc cttatgtcaa
    13321 ggcgcaaatc atggtaccac aggagttcgt cggagcagta atggagctag ctcagcgtaa
    13381 gcgtggggac tttgtgacta tggactatat tgatgataac cgtgtcaatg ttatctatca
    13441 aattcctctt gctgaaattg tctttgactt ctttgataaa cttaagtctt caacacgtgg
    13501 ttatgcaagc tttgactacg aattgtcaga atatcgccca tctaagctgg tgaaaatgga
    13561 tatccttctc aatggagata aggtggatgc tctcagcttt atcgttcaca aggactttgc
    13621 ctacgaacgt gggaaactca tcgttgataa actcaagaaa atcatccctc gccaacaatt
    13681 tgaagttcca atccaagcgg ctattggaca caagattgtc gctcgtactg atatcaaggc
    13741 ccttcgtaag aacgtacttg ctaaatgtta tggtggtgac gtttctcgta agcgtaaact
    13801 ccttgaaaaa caaaaagctg gtaagaaacg catgaaatcc atcggatcag ttgaagttcc
    13861 gcaagaagcc ttcctcagcg tcttgagtat ggatgaagaa taagttatca gaaatgcctt
    13921 tccttgttca caggaaattt atataagaat caatagtaaa gcaggcttag atggtctgct
    13981 tttttagttt ttatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttaccgta
    14041 tgtatggtt
//
LOCUS       DAVLTT010000047        13655 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLTT010000047 DAVLTT010000000
VERSION     DAVLTT010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13655
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.047"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..138
                     /locus_tag="VYN15_001570"
     CDS             <1..138
                     /locus_tag="VYN15_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1452872.1"
                     /translation="RSKVENIFAKVKTFKMISTTYRNHRKRFGLRMNLIAGIINHELG
                     F"
     gene            187..651
                     /locus_tag="VYN15_001571"
     CDS             187..651
                     /locus_tag="VYN15_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV1452873.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSKDAVTLDELQSRTIALRSLKHDRGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            808..1233
                     /gene="lacA"
                     /locus_tag="VYN15_001572"
     CDS             808..1233
                     /gene="lacA"
                     /locus_tag="VYN15_001572"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV1452874.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1264..1779
                     /gene="lacB"
                     /locus_tag="VYN15_001573"
     CDS             1264..1779
                     /gene="lacB"
                     /locus_tag="VYN15_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV1452875.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1790..2719
                     /locus_tag="VYN15_001574"
     CDS             1790..2719
                     /locus_tag="VYN15_001574"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV1452876.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIKGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2721..3701
                     /gene="lacD"
                     /locus_tag="VYN15_001575"
     CDS             2721..3701
                     /gene="lacD"
                     /locus_tag="VYN15_001575"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV1452877.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            3935..4771
                     /locus_tag="VYN15_001576"
     CDS             3935..4771
                     /locus_tag="VYN15_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1452878.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4807..5124
                     /locus_tag="VYN15_001577"
     CDS             4807..5124
                     /locus_tag="VYN15_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1452879.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5124..6815
                     /locus_tag="VYN15_001578"
     CDS             5124..6815
                     /locus_tag="VYN15_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1452880.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIENGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FNLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            7030..8436
                     /gene="lacG"
                     /locus_tag="VYN15_001579"
     CDS             7030..8436
                     /gene="lacG"
                     /locus_tag="VYN15_001579"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1452881.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8479..8664
                     /locus_tag="VYN15_001580"
     CDS             8479..8664
                     /locus_tag="VYN15_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV1452882.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWDTISFDSDFMPFQQS"
     gene            complement(8943..9704)
                     /locus_tag="VYN15_001581"
     CDS             complement(8943..9704)
                     /locus_tag="VYN15_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1452883.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9992..10954)
                     /gene="nrdF"
                     /locus_tag="VYN15_001582"
     CDS             complement(9992..10954)
                     /gene="nrdF"
                     /locus_tag="VYN15_001582"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV1452884.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(11142..13301)
                     /gene="nrdE"
                     /locus_tag="VYN15_001583"
     CDS             complement(11142..13301)
                     /gene="nrdE"
                     /locus_tag="VYN15_001583"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV1452885.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13382..13600)
                     /gene="nrdH"
                     /locus_tag="VYN15_001584"
     CDS             complement(13382..13600)
                     /gene="nrdH"
                     /locus_tag="VYN15_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV1452886.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
BASE COUNT         4203 a         2464 c         2806 g         4182 t
ORIGIN      
        1 agaagcaagg ttgagaacat ctttgccaaa gtaaaaacgt ttaaaatgat ttcaacaacc
       61 tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt tgattgctgg cattatcaat
      121 catgaactag gattctagtt ttgcaggaag tctaataaag aaactagcaa ggtcaggcct
      181 tactttattg gtggacatcc aggatttaat tgtcctctac ttgatgatga agtctatgaa
      241 gattattatc tagagtttga gaaagaagag acttgctctg ttccacgtcc tttcccagaa
      301 acaggtatgt tggatttcca agatagaagt ccatggctag agggacaaaa agaaatagat
      361 cttagttatg atcttttcag caaagatgca gtgactttgg atgaattgca atctcgaaca
      421 attgcccttc gttctcttaa acatgatagg ggattgaaag tgcattttgc agaatttcca
      481 aacctcatca tctggtcaac tttgaacaag ggacctttca ttacctttga accatggtct
      541 ggcttgtcaa cattccttga agaaggagat catttagaag ataagaagaa tgtttgtctc
      601 ttagaagcca atcaggttga agaattaggg tttgagatag aagttttata aaaaagtaaa
      661 aaataaataa caaaaacaaa cacaaactgt tgacttcttc aaacaatagt agtatattat
      721 gtttgtgagg actaattgac tgttttttaa agacagccaa tacactgctg gaatccagca
      781 tagaaaaaat aaaaaggagt atacaatatg tctattgtta tcggtgcaga tgctgcaggt
      841 ttgagattga aagaagttgt gaaagacttc ttagaaaaag aaaacttcca ccttgtggat
      901 gttacagctg aaggtcaaga ctttgttgat gtgactctcg ctgttgctgc agaagtaaac
      961 aaagaagaac aaaaccttgg tatcgtgatt gatgcttatg gagctggtcc atttatggtt
     1021 gcaactaaga tcaaaggaat ggttgctgca gaagtttctg atgaacgttc agcttatatg
     1081 actcgtggcc acaacaactc acgtatgatc actatgggtg cacaacttgt tggtgatgaa
     1141 ttggctaaaa acatcgctaa aggatttgtt aatggtaaat acgacggtgg tcgtcaccaa
     1201 atccgggttg acatgttgaa caaaatgggc taattagatt atagtaagaa aggtaagtta
     1261 aaaatgagaa ttgcaattgg atgtgaccac atcgtaacag atgaaaaaat ggcggtttca
     1321 gaatttttga aatcaaaagg atatgaagtc attgactttg gtacatatga ccatacacgt
     1381 actcactacc caatctttgg taaaaaagta ggggaagctg taactagcgg tcaagctgat
     1441 cttggagtat gtatctgtgg tactggtgtt ggtatcaaca acgctgtaaa taaagttcca
     1501 ggtgttcgtt ctgccttggt tcgtgatatg acaacagccc tttatgctaa agaacaattg
     1561 aacgctaacg ttattggttt tggtggtaaa attactggtg aattgcttat gtgtgatatc
     1621 atcgaagctt tcatccatgc tgaatacaaa ccaactgaag aaaacaaaaa attgattgcg
     1681 aaaattgaac atgttgaaag tcacaatgct caacaaacag acgcaaactt ctttacagaa
     1741 ttccttgaga aatgggatcg tggagaatac cacgactaag aggtgaccta tgattttaac
     1801 agtcacaatg aacccatcca tcgatatttc ctatcccttg gatgagttga agattgatac
     1861 tgtcaatcgt gtggtggatg taaccaaaac ggctggtggt aagggactca atgttacccg
     1921 agtactttca gaatttggcg attctgttct tgctactggt ttagtgggtg gcaaacttgg
     1981 tgagtttttg gttgaacata tcgataatca agtaaagaaa gatttcttct caattaaggg
     2041 agaaactcgt aactgtatcg ctattctcca cggagacaac caaacagaag ttcttgaaaa
     2101 aggtcctgaa gtattggaac aggaaggtca agagtttttg gaacatttca aaaaactctt
     2161 ggagtcagtt gaagtagtag ccatctcagg tagtctgcca gctggccttc cagttgatta
     2221 ctatgcgagc ttggtagaac ttgctaatca agctggcaag cctgtagtct tggactgctc
     2281 aggtgcagca cttcaggctg ttcttgaatc accccataaa ccaacagtca tcaaaccaaa
     2341 taatgaagaa ttgtctcagc ttcttggaag agaagtttct gaggatttgg atgaattaaa
     2401 agaagtactt caagaacctt tgtttgcagg gattgaatgg attatcgttt cacttggtgc
     2461 caacggtact tttgccaaac atggtgacac tttctacaag gtagatattc ctagaattca
     2521 ggtggtaaat cctgttggat ctggagactc tactgtggca ggaatttctt caggacttct
     2581 tcacaaagaa tcggatgcag aattactcat caaggcaaat gtccttggta tgctcaatgc
     2641 tcaagaaaaa atgactggtc atgtcaacat ggccaactat caagctctat atgatcaatt
     2701 aatagtaaaa gaggtataaa atggctttaa cagaacaaaa acgtgtacgc ttagaaaaac
     2761 tttctgatga aaatggtatc atctcagctc ttgcatttga ccaacgtggt gctttgaaac
     2821 gcctcatggc tcaacaccaa acagaagaac caactgtggc ccaaatggaa gaacttaaag
     2881 tcttggtagc agatgaattg actaaatatg cttcatctat gcttcttgac cctgagtatg
     2941 gacttccagc aactaaagct cttgatgaaa aagctggtct tctccttgct tatgaaaaaa
     3001 caggttatga cacaacaagc acaaaacgct tgccagactg cttggatgtt tggtctgcaa
     3061 aacgtattaa agaagaaggt gcagatgcag ttaaattctt gctttactat gatgtagata
     3121 gctcagacga actcaatcaa gaaaaacaag cctacatcga acgcatcggt tctgagtgtg
     3181 tggctgaaga tatcccattc ttccttgaaa tccttgctta cgatgaaaaa attgcggatg
     3241 caggttctgt agaatacgct aaagtaaaac cacacaaagt tatcggcgct atgaaagtct
     3301 tttcagaccc acgctttaac attgatgttt tgaaagttga agttcctgtt aacattaaat
     3361 atgttgaagg cttcgctgaa ggtgaagtag tttatacacg tgaagaagca gcagccttct
     3421 tcaaagcgca agatgaagca acgaacttgc catacatcta cttgagtgct ggtgtatcag
     3481 ctaaactctt ccaagatact cttgtatttg ctcatgaatc aggtgcaaac tttaacggag
     3541 ttctttgtgg ccgtgctaca tgggcaggat cagttgaagc ttacatcaaa gatggtgaag
     3601 cagcagctcg cgaatggctt cgcacaactg gatttgaaaa cattgacgaa ctcaacaaag
     3661 ttcttcaaag aacagcaact tcatggaaag aacgcgtgta agaaagtcct cctagtttag
     3721 gaacatgaat ctaaaaaaat ttaaaaaaag ttgtatgtaa aggtttacaa aataacttac
     3781 ttgtgctata cttaaatcac aagttaatac aaggtgagtg ttactaagta atattaggca
     3841 tgatcacagg tgaattagaa atcagctgat tttctagttc atttgtggtc attttttgta
     3901 ctcatatacc tttaaaatat aaaaggaggt tgacatgtat cgaattctaa atccaatgaa
     3961 tcacaatgtc tcgcttgtca gaaatgataa gggagaagag gtgattgtaa ttggtaaggg
     4021 gattgcattc ggaaagaaga agggggattt gattgctgaa aatcaggttg agaaaatctt
     4081 tcggatgaag accgaagagt ccagagaaaa ctttatggct cttctcaaag atgttccgct
     4141 tgattttatc acagtgacct atgaaatcat tgataagcta tcaaagaaat atcattatcc
     4201 gattcaagag tatctctatg taaccttgac agatcatatt tactgttctt atcaagctct
     4261 aactcaagga aggtacaagg atagtaatct gccagatatt tccgctaagt atcctgtcgc
     4321 ttttcaaatc gcaaatgaag cttttgaaat ttaccgtcag aagctagcag atcattttcc
     4381 tgaggacgaa attattcgga ttgcttatca tttcattaat gctgaaggtg aaaatgaagt
     4441 ggaacttgtg gagtcgattg ataagaggaa agaaattctc aggaatgttg aagaagtttt
     4501 aacggactat gcaattcaac gaactaaaaa gaataaccat ttctatgatc gctttatgat
     4561 ccatttgaat tatttcttgg attatttaga cagatctaga gatgataacc aatcacttct
     4621 ggatatggaa gatcatatta aacaatccta tccaaaagcc ttcgagattg gttccaagat
     4681 ctatgatgtg attacgcaac atacgggtct tgatttgtat aaaagtgaac gagtttatct
     4741 agttctacat atccaacgtt tattgtcata aaaatttatt taaaactata taaggagaat
     4801 tctatcatga atagagaaga agtaacattg ttaggttttg aaatcgtagc ctatgctggc
     4861 gatgctcgtt caaaactatt ggaagccttg aaggctgctg aagctggtga ttttgaaaaa
     4921 gcggacgctc tggtagagga agctggtagc tgtattgcag aggctcacca cgcgcaaaca
     4981 agtctattga ctaaggaagc ttctggtgag gacttagcgt atagtgtgac catgatgcat
     5041 ggtcaagatc acttgatgac aactatcttg ttaaaggatt tgatgcacca tttgatcgaa
     5101 ctctacaaga gaggagttaa ataatgaaca aactaattgc atttatcgag aaaggaaagc
     5161 ctttctttga gaaactatct cgtaatatct atcttcgtgc tattcgtgat ggtttcattg
     5221 caggtatgcc tgttattctc ttctcaagta tctttatctt gattgccttt gtaccaaact
     5281 catggggctt taaatggtct gatgaagttg tagcctttct gatgaaacct tatagctatt
     5341 ctatgggtat tctggctctc ttggtagctg gtacaacagc taagtcattg accgactcag
     5401 taaaccgtag catggagaaa accaatcaaa tcaactatat gtcaacgctg ttagcagcga
     5461 ttgttggttt gttgatgttg gcagctgatc ctatcgaaaa tggtctagct actggattct
     5521 tggggacaaa aggtttgctt tcagccttcc ttgctgcctt tgttactgta gccatctata
     5581 aggtttgtgt taagaacaac gtcactattc gtatgcctga cgaagttcca ccaaatatct
     5641 cacaagtctt taaagatgtg attccattca ctctatctgt tgtttctctt tatgctcttg
     5701 acttattagc acgtcatttt gttggttcta gtgtggcaga atcaatcggt aaattcttcg
     5761 caccactctt ctcagcagca gacggatacc ttggtattac cattatcttt ggtgcctttg
     5821 ccttcttctg gtttgttggg attcatggtc catctatcgt tgaaccagct atcgcagcta
     5881 ttacctatgc caatgccgaa gtcaacttga accttctcca acaaggtatg cacgctgaca
     5941 agattcttac ttctggtaca caaatgttta tcgttaccat gggtggtact ggtgcgacac
     6001 tggttgttcc attcatgttc atgtggttaa caaaatcaaa acgtaaccgt gcaatcggac
     6061 gtgcttcagt agttcctacc ttcttcggtg taaatgaacc aatcttgttt ggtgcacctc
     6121 ttgttttgaa tccaatcttc ttcattccat ttatctttgc tccaattgca aacgtatgga
     6181 ttttcaaatt ctttattgaa acacttggaa tgaattcatt tactgctaat ctaccatgga
     6241 caaccccagc tccactaggt ctagttcttg gtacgaactt ccaagttcta tcattcattc
     6301 ttgctgctct tctaatcgtg gttgacgttg tcatttacta tccattcctt aaagtttatg
     6361 acgaacaaat tcttgaagaa gaacgttcag gtaagtctaa tgatgaattg aaagaaaaag
     6421 ttgctgcaaa cttcaacact gcaaaagcgg atgctattct tgaaaaagcg ggtgtcgatg
     6481 cagcacaaaa taccatcact gaagaaacaa atgtcctcgt tctctgtgct ggtggaggta
     6541 caagtggact ccttgcaaat gctttgaata aggcagcagc agaatacaat gtccctgtga
     6601 aagcagcagc aggcggctat ggtgctcacc gtgaaatgtt accagagttt aatctagtta
     6661 tccttgcccc tcaagttgct tcaaactttg aagatatgaa ggcagaaaca gataagctcg
     6721 gtattaaact tgctaagaca gaaggcgctc aatacatcaa attaactcgt gatggaaaag
     6781 gtgccctagc attcgtacaa gagcaattcg attaaggcta ggaactgtga aacagtctcc
     6841 catcgttacg gaaatcgcta tggcgaattt cctaatcgcc ttattaattc gtcggtaaaa
     6901 agatatcgtt tttacctcct catgtcacaa ttcagtgact tggtacaaga agtgagatgg
     6961 agaagcatgg ctcactgact cctctcctct cacttttact ttatttaaat caagaaatag
     7021 gtgaaaaaaa tgacaaaaac acttccaaaa gactttattt ttggtggcgc aacagctgct
     7081 tatcaagcag aaggtgctac acatactgat ggaaaaggac cagttgcttg ggataaatat
     7141 cttgaggata actactggta cactgccgaa ccagctagtg atttttacaa tcgatatcca
     7201 gttgacctca agctagcaga agagtatggt gtcaatggca ttcgaatttc tattgcctgg
     7261 tcacgtattt tcccgactgg ttacggccaa gtaaatgcta aaggtgttga gttttatcat
     7321 aatttatttg cagagtgtca caaacgtcat gttgagcctt ttgtaactct tcatcacttt
     7381 gacacgccag aagctctcca ctcaaatgga gacttcttaa accgtgaaaa tatcgaacat
     7441 tttgtagact acgctgcctt ctgttttgaa gaatttccag aagtaaacta ttggacaacc
     7501 tttaatgaaa ttggaccaat cggtgatggt caatatttgg ttgggaaatt ccctccaggt
     7561 atccagtacg accttgccaa agtctttcaa tcacaccaca atatgatggt gtctcatgca
     7621 tgcgcggtaa aattgtacaa agagaaaggc tataaagggg aaattggtgt tgttcacgcc
     7681 ctgcctacta aatatcctct agatcctgaa aatccagcag atgttcgtgc agcagagttg
     7741 gaagatatca tccacaataa attcatctta gacgcaactt atctaggtcg ctattcagct
     7801 gaaaccatgg aaggtgtcaa ccatatctta tcagtcaatg gtggtagttt ggatcttcgt
     7861 gaagaagatt ttacagcatt agaagctgca aaagacttga atgatttcct aggaatcaac
     7921 tactatatga gtgactggat ggaagccttt gatggagaaa ctgaaattat ccataatggt
     7981 aaaggtgaaa aaggaagctc taagtatcaa atcaaaggta ttggtcgtcg tgtagctcct
     8041 gactatgtat cacgcacgga ttgggattgg attatctacc ctcaaggttt gtatgaccaa
     8101 atcatgcgtg tgaagaaaga ttatcctaac tacaagaaaa tttatatcac tgaaaatggt
     8161 ctcggctata aagatgagtt cgttgataac actgtttacg atgatggtcg tattgattac
     8221 gtgaaacaac acttggagat cttgtctgat gcgattgcag atggagctaa tgtaaaaggt
     8281 tacttcattt ggtcattaat ggatgtcttc tcatggtcaa acggttatga gaaacgttat
     8341 ggtctcttct acgtagattt tgaaactcaa gaacgttatc ctaagaaatc agctcactgg
     8401 tacaagaaag tagcggaaac tcagattata gactagtaga attagtcatt agatatagaa
     8461 ttttagtgag tcaaaaagat gttcaaagat tttatccaat ctatttatga aaaagtttat
     8521 attataaatt tcgaaaaatg ctctcaaata ccgtgtttga cgagtgaaga attgaaaagt
     8581 cttggaaaat ggtatgtctc gactggtaaa gaatgggata ctatctcctt tgattcagat
     8641 tttatgccgt ttcaacaatc gtaaccaatt tctcaaaaaa gttaaatctt atatttagta
     8701 ctctgtaaaa ctcttatcta atcacgttgc ttatactcaa tgaaaatcaa agagcaactt
     8761 taaactagga agcgagtcgc agatttctca atgcatagct ttgaggaatt gggcaaaaag
     8821 tctttgatat agaaaaacgc atagtatcag gtgttgaaac acctgatact atgcgtttta
     8881 ttgtgggaag atttactttt tttcttctga aattgagttg ttacccaggc tctttcagtt
     8941 tattaaggct tgatgacttt aatgtgttta gatagcttaa aaaggattga atcacttagt
     9001 ttagaatctg aaacaatagt atcaagattt gatacattat aaaaagtata aaaatcaaac
     9061 ttattgaact tgctatgatc tgcgagtaaa tattttttat tagaattatt taaagcgatg
     9121 cgttgagcct ctccctcttc ctcgctaaaa gtagctagag ctccgttttg aataccatta
     9181 cagctaacga aagctttaga aaattggaga ttagagagat tttgtagggt caatgtacca
     9241 acaaaagcac ctgtaatatc gcgataattt ccacctatta aaatcaaatc tgttaatttt
     9301 cgttcgctta aaatcagaaa aacaggtaga ctgttggtta cgacgcggat attgtcaata
     9361 ggcaactcac gcgcaaaaaa ctctaatgtt gttcctggtc caatgaaaat agtttctctt
     9421 tcttctacta gactgcctgc aaaatgggct atttcttgtt tttctgccgt ttggagggct
     9481 tgtttttcaa tatttgatcg ctcattagtc aaaagggagt tggttcgaag tttttcagct
     9541 ccaccatgca cacgaatcag caaatcttta tcagctaatt cctgtaaata gcgccttgca
     9601 gtcatatctg aaacggctat ttcgtccata atctgtttaa ctgttatggt tcctttacta
     9661 tttactatct ctaaaatttt ggctaatttt tcttgtttga gcatattatc acctcgtttc
     9721 ctactactat cttaccataa acaaactcat cattcaaata caaaaacaac aaaataaaac
     9781 aaaaacaaaa atatcgaggt ttattttcaa aactttcgat atttttatta agttattatt
     9841 ttgttgtttc tagtttactt tttgatggtt aagagtggtg gagaattata ctcaatgaaa
     9901 atcaaagagc aaactaggaa gctagccgca ggctgtactt gagtacggca aggcgaagct
     9961 gacgtggttt gaatttgatt ttcgaagagt attagtccaa accgtagttg tagtcatcat
    10021 cttgcatggc ttcaacttcg ccaagaaggt aaccatttcc gacttgagag aagaagtcat
    10081 ggttggaagt tcctgttgaa ataccgttca taacgattgg gttgacatct tcagctgaat
    10141 ctgggaaaag tggatcttgt cccatgttca tgagagcttt attggcattg tagcgaagga
    10201 aggttttaac ctcttcagtc caaccaacac cgtcataaag actctctgtg tagccttctt
    10261 cattttcata aagagtatag agtaggtcgt acatccattc tttgagtttt tcttgctctt
    10321 cttcaggtaa ttcattgaaa ccaagttgga atttgtaacc aatgtaggtt ccgtgaacag
    10381 actcgtcacg aataatcaat ttaatgattt ctgcaacgtt ggcaagtttg ttgttaccga
    10441 gatagtagag gggagtgaag aaaccagagt agaagaggaa ggtttcgagg aagacgctgg
    10501 caactttctt ttcaagtggg ctgccgttta ggtagatttc gttgacaatc tcagccttct
    10561 tttgtaggta aggattggta ttggtccatt cgaaaatttc ttcaatctca gccttagtat
    10621 tcaaggtaga aaagattgat gagtaagatt tagcgtggac agattccata aattggatgt
    10681 tattgaaaac agcttcctca tgtggtgtac ggatgtctgc gcgaagggct tgaaccccag
    10741 tttcagattg catagtgtca agaagggtta aaccaccaaa aacttttccg accaagtctt
    10801 tctctttgtt agatagcttt ctccagtcat ccaagtcgtt tgataaggga atacgtgtat
    10861 cgagccaaaa ttgctccgtc agtttttccc aagttgattt gtcgatgaca tcttcgatgg
    10921 cattccagtt aatggctttg tagtaagttt ccatttaaaa tctctttctg tgtttagtat
    10981 tgcgaactca caattatttc tactttacca taattctata ggagtatcgc acaaaaagtc
    11041 ggaagcccga cttttaaaat gttacataaa ttatgttatg acatagtaga tttgatttta
    11101 tcagtgctgc ttagggaaaa ataatgtttc tatgctagaa actaaatcac acagctttca
    11161 cattggttgg cgccgacttc tccaccgtca tctgtaaagg tacggacgta gtagatagac
    11221 ttgattccct tgttaaaggc atagttacga aggatggaca agtcacgtgt cgtttgttta
    11281 ttttccctct tccattcgta aaggcctttt ggaatgtcac tacgcatgaa gagggtgagt
    11341 gaaagtcctt gatccacgtg ttcagtcgca gcagcgtaaa catcgatgac tttacgcata
    11401 tccatatcgt aggcagaagt gtagtaagga atggtttctg tagacaagcc agcagcaggg
    11461 tagtagattt taccaatttt cttctcttgg cgttcttcga tacgttgcgt aatcgggtgg
    11521 atagaagcag aaacgtcgtt gatatagctg atagaaccat ttggcgctac agcaaggcga
    11581 ttttggtggt aaagaccatc ttcttgaacc ttgtcgcgaa gttcagccca atcagcaaca
    11641 ccagggataa agacattttt gaagagttct ttaacacggt ctgatgttgg aacaaattca
    11701 ccagttacat acttgtcaaa gtaacttccg ttagcatagt ctgatttttc aaagttgtgg
    11761 aaggtaatac cacgttcacg cgcaatattg tttgactcta ccaaggtcca gtagttcata
    11821 agcataaagt agatgcttgt aaattcaaca gactcaggtg aaccatattc aatgagttgt
    11881 tgggcaaggt agctgtgcag tcccatggca ccgagaccaa aggtgtgggc ttggctattt
    11941 ccatggtcaa tcgttggtac agctacgata tgtgaactat ctgtaacgaa agtaagggca
    12001 cgaaccatag cacggataga acgaccaaaa tcaggtgaag tcatcatgtt aaccacgttg
    12061 gttgaaccca ggttacatga aacatctgtt cccatttgaa ggaattcttg agcatcgttg
    12121 atcaagcttg gttcttgaac ttgaagaatc tcagaacaca agttactcat gataatcttt
    12181 ccatcaacag gatttgcacg gttagccgta tcgatgttga ctacataagg atagccagac
    12241 tcttgttgca atttagagat ttcagtttcc aaatcccgcg ccttgatttt tgtcttgcga
    12301 atatttggat ttgcgaccaa ttcatcgtat ttttcagtaa tgtcgatgta attgaatggc
    12361 acaccgtatt ctttttctac agagtaaggg ctgaagaggt acatttcttc atttttacga
    12421 gccaattcgt agaatttatc aggtactaca acaccaagtg atagagtctt gacacgtact
    12481 ttttcatcag cgttttcttt cttagttgaa aggaaagcga tgatatctgg gtgaaagacg
    12541 ttgaggtaga caacaccggc accttgacgt tgccccaatt ggttggagta agagaagctg
    12601 tcttcaaaaa gcttcataac aggaacgaca cctgaagcag ctccttcata gcctttgata
    12661 ggtgcaccag cttcacgaag gttgctgagg gtaattccca caccaccacc aatacgtgaa
    12721 agttgaagag ctgagttgat agaacgtccg atagagttca tatcatccgt cacttggatt
    12781 aggaaacaag ataccaactc cccacgacga gcacgtccag cattcaagaa ggaaggagta
    12841 gcaggttggt agcgttggtg gatgatttca ttggcaatat cgattgcaac agcttcattc
    12901 ccatcagcga aataaagggc gttgaagaag acacggtctt ccatattttc aagatagtat
    12961 tcaccgtcat tagtctttaa ggcatattga ttgtaaaatt tataagctgc catgaatgac
    13021 ttgaattgga agttttggtc tttgataaat tgagccaatt cttccaagaa ctctggacgg
    13081 tatttcttga taaaggctgt ttcgatgtag ttgtgttcaa tgaggtaatt gattttgtct
    13141 ttgattgaat caaaaaccat agtgtttgga actacatttt ctttaaagaa agcatccaag
    13201 gcttccttat ctttatgaag catgatttgt ccattaacag gacggttaat ttcgttatta
    13261 agacggaagt aagtcacgtc ttcaagatgt tttaatccca taaaatttcc cttatctaat
    13321 tacaaaagaa aggcttctaa gttagcccta aaagcagttt cttctggatg atgtactaag
    13381 attatgctaa ttgtttcagt tttcctggtt ggaaacctga aaagacttca gttggtgttt
    13441 ggataacagg agctgcgcta aaaccgagct ctttaacttg atcgacgtac tcaggttgct
    13501 catcaagatt gatttcacga taagagacat tattactgtc caagaaacgc ttggtcattt
    13561 tacattggac acaattgttt ttagaataaa cggttaccat tgtgtaactc ctcttcaaaa
    13621 tttaatacta tcttagtata tcagaaaata aaatt
//
LOCUS       DAVLTT010000048        13461 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLTT010000048 DAVLTT010000000
VERSION     DAVLTT010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.048"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..748
                     /locus_tag="VYN15_001585"
     CDS             <1..748
                     /locus_tag="VYN15_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1452887.1"
                     /translation="PAPKPAPAPAPKPEKPAEKPAPAPKPETPKTGWKQENGMWYFYN
                     TDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGAMATGWLQNNGSWYY
                     LNSNGAMATGWLQYNGSWYYLNASGAMATGWAKVNGSWYYLNANGSMATGWLQYNGSW
                     YYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQWFKVS
                     DKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            1149..2270
                     /gene="mnmA"
                     /locus_tag="VYN15_001586"
     CDS             1149..2270
                     /gene="mnmA"
                     /locus_tag="VYN15_001586"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV1452888.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2411..2866
                     /locus_tag="VYN15_001587"
     CDS             2411..2866
                     /locus_tag="VYN15_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1452889.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNRKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWKGQLRHIHLEK"
     gene            2876..4789
                     /gene="mnmG"
                     /locus_tag="VYN15_001588"
     CDS             2876..4789
                     /gene="mnmG"
                     /locus_tag="VYN15_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV1452890.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            4978..5067
                     /locus_tag="VYN15_001589"
                     /pseudo
     CDS             4978..5067
                     /locus_tag="VYN15_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(5213..6892)
                     /locus_tag="VYN15_001590"
     CDS             complement(5213..6892)
                     /locus_tag="VYN15_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1452891.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6894..7127)
                     /locus_tag="VYN15_001591"
     CDS             complement(6894..7127)
                     /locus_tag="VYN15_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV1452892.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            complement(7945..8097)
                     /gene="cibB"
                     /locus_tag="VYN15_001592"
     CDS             complement(7945..8097)
                     /gene="cibB"
                     /locus_tag="VYN15_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV1452893.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(8099..8284)
                     /gene="cibA"
                     /locus_tag="VYN15_001593"
     CDS             complement(8099..8284)
                     /gene="cibA"
                     /locus_tag="VYN15_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV1452894.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8462..9145
                     /gene="tsaB"
                     /locus_tag="VYN15_001594"
     CDS             8462..9145
                     /gene="tsaB"
                     /locus_tag="VYN15_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV1452895.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPR
                     QKEGLVVPIMDARRNNVYAGFYENAKPVLPEAHLSFAEVLEQVKDAEQVTFVGEVGAF
                     VEQIQEQLPQASYQETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            9142..9579
                     /gene="rimI"
                     /locus_tag="VYN15_001595"
     CDS             9142..9579
                     /gene="rimI"
                     /locus_tag="VYN15_001595"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV1452896.1"
                     /translation="MIEIKRIQQQPDLAKAIYAVMIAVYPVSPWTLEQIQADLFQDQT
                     WYALAYDGAEVIGFLAVQETLFEAEVLQIAVKGAYQGKGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIADRKAYYHDPVEDAIIMKREIDEG"
     gene            9569..10579
                     /gene="tsaD"
                     /locus_tag="VYN15_001596"
     CDS             9569..10579
                     /gene="tsaD"
                     /locus_tag="VYN15_001596"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV1452897.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10619..11925)
                     /locus_tag="VYN15_001597"
                     /pseudo
     CDS             complement(10619..11925)
                     /locus_tag="VYN15_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(12264..12552)
                     /locus_tag="VYN15_001598"
                     /pseudo
     CDS             complement(12264..12552)
                     /locus_tag="VYN15_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12683..12952)
                     /locus_tag="VYN15_001599"
                     /pseudo
     CDS             complement(12683..12952)
                     /locus_tag="VYN15_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            13195..>13461
                     /locus_tag="VYN15_001600"
     CDS             13195..>13461
                     /locus_tag="VYN15_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV1452898.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSN"
BASE COUNT         3862 a         2683 c         3147 g         3769 t
ORIGIN      
        1 tccggctcct aaaccagctc cagctccggc tcctaaacca gaaaagccag cagaaaaacc
       61 agctccagct cctaaaccag aaactccaaa aacaggctgg aaacaagaaa atggtatgtg
      121 gtacttctac aatactgatg gttcaatggc gacaggatgg ctccaaaaca acggatcatg
      181 gtactacctc aacagcaatg gtgctatggc aacaggttgg ctccaaaaca atggatcatg
      241 gtattaccta aatgctaacg gtgctatggc aacaggatgg ctccaaaaca atggttcatg
      301 gtactacctc aacagcaatg gcgctatggc gacaggatgg ctccaataca atggctcatg
      361 gtactatcta aacgctagcg gcgctatggc aacaggttgg gctaaagtca acggatcatg
      421 gtactacctc aacgctaacg gttcaatggc aacaggttgg ctccaataca acggatcatg
      481 gtactacctc aacgctaacg gtgctatggc aacaggttgg gctaaagtca acggatcatg
      541 gtactacctc aacgctaacg gttcaatggc aacaggttgg gtgaaagatg gagatacctg
      601 gtactatctt gaagcatcag gtgctatgaa agcaagccaa tggttcaaag tatcagataa
      661 atggtactat gtcaatggct taggtgccct tgcagtcaac acaactgtag atggctatga
      721 agtcaatgcc aatggtgaat gggtttaagc cgattaaatt aaatcatgtt aagaacattt
      781 gacattttaa ttttgaaaca aagataaggt tcgattgaat agatttatgt tcgtattctt
      841 taggtaccta tcttatgatt tcaggaaatg tcattaaaaa aacgactcct tttctctaac
      901 ttgaaaaata gattagagaa aatgggttgt tttatttatt atagttattt gaatgaagat
      961 aagaagaagg tatactcaca tcattcacat aatctgtatg ttgactataa gttttaaaaa
     1021 acaattttta agctcttcct tgtcttctcc aaccaagcgt gttataatga atactgctca
     1081 agcgaccttc aatcgtgaag cacacacgac cttcaatcgt gaataaacga atagatggga
     1141 gacttaccat gagtgataac tctaaaacac gtgttgtcgt ggggatgagt ggtggtgttg
     1201 attcgtcggt gacggctctt ttgcttaagg agcagggcta cgatgtgatc ggtatcttca
     1261 tgaagaactg ggatgacaca gatgaaaacg gcgtctgtac ggcgaccgaa gattacaagg
     1321 atgtggttgc ggtggcagac cagattggca ttccctacta ctctgtcaat tttgaaaaag
     1381 agtactggga ccgcgttttt gagtatttcc tagcggaata ccgtgcaggg cgcacgccaa
     1441 atccggacgt tatgtgcaac aaggaaatca agttcaaggc ctttttggac tatgccatga
     1501 ccttgggggc agactatgta gcgactgggc actatgctcg agtggcgcgt gatgaagatg
     1561 gcactgttca catgcttcgt ggcgtggaca atggcaagga ccagacctat ttcctcagcc
     1621 aactttcgca agaacaactc caaaaaacca tgttccctct gggacatttg gaaaagcctg
     1681 aagtacgcag actagcagaa gaagcaggcc tttcgactgc taagaagaaa gactcgacag
     1741 ggatttgctt tatcggagaa aaaaacttta aaaactttct cagcaactac ctgccagctc
     1801 agcctggtcg tatgatgact gtggatggtc gcgatatggg cgagcatgct ggtctgatgt
     1861 actatacaat cggtcagcgt ggcggactcg gtatcggtgg gcaacacggc ggtgacaatg
     1921 ccccttggtt cgttgttgga aaagatctaa gcaagaatat tctctatgta ggacaaggat
     1981 tctaccatga ttcgctcatg tcaactagcc tagaagccag tcaagtccac tttactcgtg
     2041 aaatgccaga agagtttacg ctagaatgta cggctaaatt ccgttaccgt cagcctgact
     2101 ctaaggtgac cgtccatgtc aaaggagaca aggcagaagt tatctttgcg gaaccacaac
     2161 gcgcgattac accaggacag gcagttgtct tttacgatgg agaagagtgt ctaggtggcg
     2221 gtttgattga caatgcttac cgcgatggac aagtttgtca gtacatttag attgacaaat
     2281 tttctcaatt tgctacaata ataacagcaa tagaaatgat ggtcaaagct catggatgtt
     2341 gcaggctttt ttgtcctgca cttctttgta gttttgactg tttttgtgtc gtttaaggga
     2401 aaggacaaga atgactcaac aagactttcg gacaaaagta gacaatacgg tttttggtgt
     2461 tcgggcgaca gctctgattc ttcaaaatcg caagcttcta gtcaccaaag acaagggcaa
     2521 gtattacact atcggcggtg cgattcaagt caatgaaagc acggaagacg cggtagtccg
     2581 tgaagtgaag gaagaactgg gtgtcaaagc tcaagctggg cagctagctt ttgtggttga
     2641 aaatcgtttt gaacaggacg gtgtttccta tcacaatatc gaatttcatt atctggtaga
     2701 cttactggag gatgccccat tgaccatgca ggaagatgag aaaaggcagc cctgtgagtg
     2761 gattgacttg gataagcttg aggatatcca gctagttcca gcttttttaa aaacggccct
     2821 accagattgg aaaggccaac taagacacat ccatcttgag aaataggaga gaaatatgac
     2881 atatcatttt actgaagaat acgatattat tgtaattggt gcgggacacg ctggggttga
     2941 ggcttccttg gccgctagcc gtatgggctg taaggtcctg cttgcgacca tcaatattga
     3001 aatgctggct ttcatgcctt gtaatccctc tatcggtggt tctgctaagg ggattgtcgt
     3061 acgtgaagtc gatgccctcg gtggcgagat ggccaagacc attgacaaga cttacatcca
     3121 gatgaagatg ctcaacacag ggaaggggcc agccgttcgt gcccttcgtg cgcaggctga
     3181 caaggaactt tactctaagg aaatgcgcaa gacagttgaa aaccaagaaa atctgaccct
     3241 tcgtcaaacc atgattgatg agattttggt ggaagatggc aaggttgtcg gtgtgcgtac
     3301 agccacccat caagaatatg ctgctaaggc tgttattgtg acgacaggga ctgctctccg
     3361 tggggaaatt atcatcggag acctcaagta ctcatcaggt cctaaccaca gcttggcttc
     3421 tattaaccta gctgataatc tcaaggaact gggcctcgaa atcggtcgtt tcaagacagg
     3481 aacccctcca cgtgtcaagg cttcttctat caactacgac gtgacagaaa tccaaccagg
     3541 agatgaagcg cctaatcact tctcatacac ttcacgtgat gaggattatg tcaaggacca
     3601 agtgccatgc tggttgacct acaccaatgg taccagtcat gagattatcc aaaacaacct
     3661 ccaccgtgcg cctatgttta caggtgtggt caagggagtg gggcctcgtt actgtccgtc
     3721 gattgaagac aagattgtgc gctttgcgga caaggaacgt caccaactct tccttgaacc
     3781 agaagggcgc aatactgagg aagtctatgt gcaaggactt tcaaccagtc tgcctgagga
     3841 tgtccagcgt gacttggttc attccatcaa aggtttggaa aatgcagaga tgatgcggac
     3901 aggttatgct attgagtatg atatggtctt gcctcatcag ttgcgtgcga ctctggaaac
     3961 caagaaaatc tcaggtctct tcactgctgg tcagacaaat ggaacgtcag gttacgaaga
     4021 ggcagcaggc caagggatta tcgcgggtat caatgcggct ctgaaaatcc aaggtaagcc
     4081 tgagttgatt ttgaagcgaa gtgacggtta tatcggggtg atgatcgacg acttggtgac
     4141 caagggaacc attgaacctt accgtctctt gaccagtcgt gctgaatatc gtctcattct
     4201 tcgccatgac aatgctgata tgcgcttgac tgagatggga cgcgagattg gccttgtgga
     4261 tgatgaacgc tgggctcgtt ttgaaatcaa gaaaaatcaa tttgataatg agatgaaacg
     4321 cctagacagt atcaaactca agccagtcaa ggaaaccaat gctaaggttg aggaaatggg
     4381 cttcaagccg ttgacagatg cggtgacagc caaggaattc cttcgccgtc cagaagtttc
     4441 ttaccaagat gtggtggcct tcatcggacc agctgcagaa gacttggatg acaagattat
     4501 cgaattgatt gaaacagaaa tcaagtacga aggctatatt tcaaaagcca tggatcaggt
     4561 tgccaagatg aaacgtatgg aagaaaaacg cattccagcc aatattgact gggatgacat
     4621 cgattctatt gcgacggaag ctcgtcagaa gttcaaactc atcaatccag aaaccatcgg
     4681 ccaagccagc cgtatttcgg gggtaaaccc agcagatatt tctattttga tggtgtatct
     4741 ggaaggtaaa aatcgtagta tttctaaaac tcttcaaaaa tcaaaatgat acgtcgtcgg
     4801 cttcttacga atgagttcaa agcttggctt tgattcatct ccagcctccc atagtttccc
     4861 gaactatggg agctaactca agttatgcat tttcctagcc ttctggtctg attttcattg
     4921 agttttaatc tcaaaagaaa gcatagagaa aaacagctcc gaagacgggg ctgttttgtt
     4981 gacttgtact caatgaaaat caaagagcaa actaggaagc tagccgtagg ttgctcaaag
     5041 cactgctttg aggttgtaga tagaactgac gaagtcagct caaaacaccg ttttgaggtt
     5101 gtggatagaa ctgacgaagt cagctcaaaa caccgttttg aggttgtgga tagaactgac
     5161 gaagtcagta acatatatac ggcaaggcga agctgacgtg gtttgaagag tattattctt
     5221 catctggtgt gaggatcatc gggatgatga tcggttcacg ttcggtattt tcatagagga
     5281 aggggcgaat agcgttgaca atggcaccat tgacagattg cacgctagca tccttatttt
     5341 tcagtgcgat acgaatggca ttgaagagga tacgctggct ttggcgaatc aagtcgccag
     5401 actctctcat gtagacaaag cctcggctga ggatgtctgg accagataga atcatctgcg
     5461 atttgaagtc aacagttgcg actgccagaa cgacaccgtc ttcagataga tcgcgacgat
     5521 ctttgaggac agctgcgcca atttcaccga tacgatttcc atcgacatag atatcttggg
     5581 cgttgaaatg acctgcgata cgagctgagt cagcagtaag ggcaagcaca tcgccattgc
     5641 tcatgataaa gatattgtcc ttctcaacac cagtatccac tgctagtcca gcgtggactt
     5701 tttgcatgcg gtattcaccg tggacaggca tgaagtattt tggcttaatc aagcagagca
     5761 tgagtttttg ctcttgctga ccaccgtgtc cagatgtatg gatattgttc actttaccgt
     5821 ggataacttc gacaccagct tcagaaatga tgttaatcag cttgttgacg ctagtagtgt
     5881 ttccagggat gggactagaa gagaagataa cggtatcacc tggttgtaat tgtacttgac
     5941 ggtgggttcc gttggcgata cgagagaggg ctgccatagg ctcaccctga ctacctgtac
     6001 agaggataag aacttctcct gcaggataat ctttgatttc atttggctcg ataaaggttc
     6061 ccttaggagc tttgatgtag ccaagatcga ttccgttgac aatggccttt tccatagaac
     6121 gaccaaagac cgcaatcttg cgtccagtct taacagcagc ttctgttgcc tgctggagac
     6181 ggaagatatt tgaggcaaag gatgcaaaga tgatacgtcc ttcaatacct tggataatct
     6241 tcataatgga ctgaccaacg actttttcag agttggtaaa ggttggtact tccgcatttg
     6301 tcgagtcaga caggagacag agcacacctt cttcaccaag cgcagccata cgatgcaagt
     6361 ccgcaggttc tccaactgga gtaaagtcga acttaaagtc ccccgtacag acgattttcc
     6421 cttgaggagt atgaatgaca atccccaaag gctctggaat agagtgagtc gttctaaaga
     6481 aagttgcctt gagattttta aaggtcaact cggtgttgtg gttgatttcg taaagtttgg
     6541 cgttgcgcaa gaggccgtgt tcttcgagtt tcccacggat caaagccaag gcaagcggtc
     6601 cagcgtagat agggacattt gcttgcttga gtaggaacgg aatcccacca atgtggtcct
     6661 cgtgtccgtg tgtgattaaa acagccttga cgcggtcgat attgtccacg atgtaagagt
     6721 agtcaggaat gacatagtcg ataccaagca agtcatcttc tgggaattta atcccagcat
     6781 cgacgatgat aatctcgtct tggtattcaa ttccgtaagt gtttttcccg atttctccta
     6841 gaccaccgat ggcaaaaacg ccgacttctt caggtttaag agtgtaggcc atattagaac
     6901 tccgtaattt cgaaggcgcc agtttctttt tcgtaatcga gcaatttgtc agacaagagt
     6961 tcgatatatt cgatattgta ctctgggcga ttttcttcga caagttggcg agcagtgata
     7021 cggccctcaa gttctgagct ggcatcgatg tctaggtaaa gcgcgcgtgt tgtttcacgg
     7081 cgtgggctac gttcttttgt ttcttgataa aaaactttgt aaatcatata gttcctttct
     7141 atttacaggt cagcttattc caaactttta gcagatattt gcttgatttc attccatttt
     7201 gtgtctagat tgaccttgat tcgttacaat tatttcaatt ataccacaaa atgaaaaatt
     7261 agtaaaagac ggaaacgaga aagttagggg gcaatttctt tggtaagcgt ttacaaaaat
     7321 aaagaaaatg tattatgttg ataacggaag tgaaatttat tgcttgtcat aattccatat
     7381 agattttaag tcaaggaggt tgccctatgt ataacttatt tgcttttgct atcggagttc
     7441 gtttgttagc ttttatcgtt tttgttgctt gcgtttatgg aggaaatctt ccatttgcca
     7501 aactggaacg atgacaaacc aagttcttgt ggaaaatgac ctttgtgact ctctactcgc
     7561 tttttctcct cctcgtgccc tatgtcgttt ggtttgtatt ttactttgga ttaaatgctt
     7621 agatgccctg cttatgctgg ggttttttgt ttggggatgt agagatagta gatttacgac
     7681 acgaaaattc caccccatct atcaagatga ggtggtcttt gcatttttct aaaatgacat
     7741 gacaatggaa ttttcaaagc ttattatttt tatgggagtc attgttctgc tcaaaaatag
     7801 agttgaagca taaaaataaa acaatacaaa cagataaatc gaatggtaaa gggatagtag
     7861 taatgttcaa atcattgaga atgctgagca aactgtaaga gatgaagaca ataaaattta
     7921 tccttctaaa aatgtgtttc ttatctagca tgacttacca aactttttac gaaggtcttt
     7981 tccaatggta taacctgcca taaataaagc gataccaaca cctacaccaa agccaccctt
     8041 gatttcttgc aattccttat tagaaatttc acgatagttg ttcaaatttt tcatcatatt
     8101 aatctcctcc taaaaaataa ccagctgcca aaccagaacc tataagtgct gttccacctg
     8161 caatagcctt ccaagatact gctactccaa agataaccaa gggagcgaga ccgccatcaa
     8221 tatctgataa ttcattttca gataaggata aaaattgatt gtcaagaatg tcaaaatttg
     8281 tcattgaact ttcctccttt tttcttgttc acttttatat tcggaaaaga aaaggaaaag
     8341 tgagcatttt tttaaattat ttttagttaa gtgagggcac tcttgtctgg gggcaaagaa
     8401 aattcccatg tgccagcttt tgtagtataa tagtaagcag acaaaaagat aggaatgtgt
     8461 tatgaaagta ttagcttttg atacgtccag caaggctctt tctctcgcta ttttagagga
     8521 caagcaggtt cttgccgaga cgacgattaa tattaagaaa aatcacagta ttactcttat
     8581 gcctgccata gattttttga tggcaagttt ggattggaca cccaaggatt tggaccgaat
     8641 cgtggtagct gaagggccgg gtagctatac aggcttgcga attgcggtag caactgccaa
     8701 gaccttggct cataccctga acattgagtt agttgggatg tctagtctat tggctctggt
     8761 gccacgccaa aaagaaggct tggtggttcc tatcatggat gcgcgtcgca acaatgtcta
     8821 tgcaggcttt tatgaaaatg ccaagccagt cttgccagaa gcgcatctgt cttttgcgga
     8881 agtgctagag caggtcaagg atgctgagca ggtgaccttt gtcggagaag ttggagcctt
     8941 tgtggaacag atccaagaac aactaccaca agccagctac caagaaacct tgccaaatgc
     9001 agctaatcta gctctttggg cttgggacaa agaagcagac tccttgcacg actttgtgcc
     9061 aaattacctc aagcgtgtcg aggctgagga aaactggctc aagaaccata ccgagtctgg
     9121 cgagtcttac attaaacgcc tatgatagaa atcaaacgaa tccaacagca gcctgatcta
     9181 gctaaagcca tctacgctgt tatgatagct gtttacccag tcagtccttg gacgctggaa
     9241 caaatccaag ctgacctgtt ccaagaccag acttggtatg ctctggctta tgatggggca
     9301 gaagtgattg gctttctagc tgttcaggag actctctttg aagcagaagt cctgcaaatc
     9361 gctgtcaaag gagcctatca gggtaagggc attgcgtcag ccttgtttgc tcaattgccg
     9421 acagataagg agattttcct cgaagtcaga aagtcaaatc aacgagcgca agcattttac
     9481 aagaaagaaa aaatggcggt catcgctgat cgaaaggcct actaccatga cccagtcgag
     9541 gacgccatta tcatgaagag agaaatagat gaaggataga tatattttag catttgagac
     9601 atcctgtgat gagaccagtg tcgccgtctt gaaaaacgac gatgagctct tgtccaatgt
     9661 cattgctagt caaattgaga gtcacaaacg ttttggtggc gtagtgcccg aagtagccag
     9721 tcgtcaccat gtcgaggtca ttacagcctg tatcgaggag gcattggcag aagcagggat
     9781 taccgaagag gacgtgacag ctgttgcggt tacctacgga ccaggcttgg tcggagcctt
     9841 gctagttggt ttgtcagctg ccaaggcctt tgcttgggct cacggacttc cactgattcc
     9901 tgttaatcac atggctgggc acctcatggc agctcagagt gtggagcctt tggagtttcc
     9961 cttgctagcc cttttagtca gtggtgggca cacagagttg gtctatgttt ctgaggctgg
    10021 cgattacaag attgttgggg agacacgaga cgatgcagtt ggggaggctt atgacaaggt
    10081 cggtcgtgtc atgggcttga cctatcctgc aggtcgtgag attgacgagc tggctcatca
    10141 ggggcaggat atttatgatt tcccccgtgc catgattaag gaagataatc tggagttctc
    10201 cttctcaggt ttgaaatctg cctttatcaa tcttcatcac aatgccgagc aaaagggaga
    10261 aagcctgtct acagaagatt tgtgtgcttc cttccaagca gcagttatgg acattctcat
    10321 ggcaaaaacc aagaaggctt tggagaaata tcctgttaaa accctagttg tggcaggtgg
    10381 tgtggcagcc aataaaggtc tcagagaacg cctagcagcc gaaatcacag atgtcaaggt
    10441 tatcatcccc cctctgcgac tctgcggaga caatgcaggt atgattgcct atgccagcgt
    10501 cagcgagtgg aacaaagaaa acttcgcagg ctgggacctc aatgccaaac caagtcttgc
    10561 ctttgatacc atggaataaa gagtggctct ttgtcaagtg tagtgggtag gcgaaaagct
    10621 acaatctgga gagtacgaaa ttcgtactct cttttttgat gttcaaagtc atcaaaatcc
    10681 gttttttaaa attgttaaag ttccggaaac caaaggcttt gcgcttgata accttaataa
    10741 aattattggt cgcttcaagt ttagcgttgg aataaggcag cttaagtgcg ttgataatct
    10801 tatctctatc ccttaaaaaa gtccaaaaga ccgtttgaaa aagcggatga accgttggca
    10861 gttcttgctc aatcaatcca aagaaatggt cggcattctt ctcttgaaaa tgaaagagca
    10921 ggagttgata gagttcgtag tgaacctgta atccctcaga gtaagaaagc agcttatctc
    10981 gtacttcccg atgggttaag tgcattcgaa acgtgggctg atagaatcgt ttctgacaga
    11041 gcttgaagct atcctggtgt agtaaatcag tccagtggac tgatttagcc cgagcctaga
    11101 aacgaaaaag cgagggttcc aaaagcgctt gagcgcccga tactccaagg attttcggtc
    11161 aaattggttc atgatttgga ttcgtactcg gttcatagct cggctcagat gttggacaat
    11221 gtggaagcgg tcaagaacaa tcttcgcctt tggaaagagt tgcttagcga gccgataata
    11281 agggctgtac atgtccatgg tgatgacctc gaccagctcc cgaacctctc tctgatagcg
    11341 ttggaaatgg tttcgaatca ccgcatgagt tcgcccgtct aaaattgcga ggatggattt
    11401 ggactcaaaa tcttgggcaa tgaagctcat tttgctcttt ttgaagctat actcatccca
    11461 actcataact tttggcaact tggtccaatc ggtttcaaac ttaaattccc tcagttttcg
    11521 gatgacggtg gaagttgaga ccgccaatct gtgggcaatc tcagtcatag actgcttttc
    11581 aaggaggagc tgagcgattt tttgtctcac catgttggaa atctggcaat ttttcttgac
    11641 aatggatgtt tgagaaacga ccaccttaag gcaattcttg cactgaaagc ggcgcttttt
    11701 gagatgcagt accgtgggta aaccctgaca gtcgagaagc ggaattttag aggctttctg
    11761 gaagtcgtat ttgatcatct tcccttgaca atgaggacaa ggaggagtgg gggaatccaa
    11821 ctttgcctga acgactagat gggtttggta tttcagaaca gacaagattt tgatattttt
    11881 gtcttccaat ccgagcaaat ctgtggtatt cttaagttgt tccatatgac ccctttctaa
    11941 tgagttggtt agacgctttt cattataggt catatggggc tttttttcta caagaaacga
    12001 ccctataatt cctggggtgg gattacccac tacagaaatt atagagccaa aacattccaa
    12061 agtcttgtct gactctggaa tgttttctgt tcacagttgt tttgtaactg cctaataagt
    12121 aaccgcgcta taacgaggta tctaccgaga ttgtcaattc tccagtatac tgttataaaa
    12181 aacaaaactg gaggattttt ttatgtcccc ccatcgtccc atcgactgtt ccgtagctgc
    12241 ccaataacgg agtatagtcg tctgaaacaa gaataggaca aaagtgcctc aagaaaagca
    12301 tcgtaatttg acaatattat tctgagatgt ttttgatgta agcccatatt ttctcaatgg
    12361 gattatactc gggtgaatag gtaggaagtg gtaacagtct atgccctgct ccttacacat
    12421 gttcattctg tgaaaccttg cattgtccat aatgataagg gatggtgtat ctaaagtagg
    12481 tagtaagaat ttttggaagc aagcttcgaa aaagtcactc gtcatcgtat ctttataggt
    12541 catcggagcc atagtatatt gaaacaaaaa agggtattag tacttctata acagtatcgc
    12601 aatctctggt gtgcgttgtc tcgatcttaa ttcaaataat tatatcttct tccagagaga
    12661 ctaactgcct gctcaaggat caatcatatt cgagataaaa ataggtctca acccctgtct
    12721 cataaatata aataggagtc aggtagctta agtgattcaa ttctttaagg aaccgattta
    12781 ctttttcttg gtcttgttcg cagtaggtac ggctcttttt tagactatat cccatagcct
    12841 ttagagcgta atgaatagtt gttggaggac agttgaattc agcagctatt tcagtcaaat
    12901 aagcatcggg atgagtttca atatagatct ttaatttatc tctatcaact ttttcaatta
    12961 atagtggaag ttttcttgaa gttagtgtat tgaaacgttt ttatacagtg ctaaaatttg
    13021 aagtgtagtg cagatgtatt tgtaatagta ttatagcaat tctttggaga aggtcgagac
    13081 aagagaaaat aggtatcttt gagatataag catgatttac tataaaatta ttgagttatt
    13141 cataaaaatt tctctatcaa atatcataat gcgtcgttta aggagatggt tacaatgcaa
    13201 tatagttgtg gaaaaataaa tattaatatc cctgatggat atggagacat taaggatata
    13261 gtgttttcgg ctcatattat agttaggtat aataatggac attgtggagg tatagatccg
    13321 catataattg gactttgtaa aaagcagatc agaaggatgt ctctatatcc tattttgata
    13381 atcgtatcta gagattcaaa ggttattgat gattataaaa atttagatat tgcctatgtt
    13441 gattgtactc aatgttcaaa t
//
LOCUS       DAVLTT010000049        13442 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLTT010000049 DAVLTT010000000
VERSION     DAVLTT010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13442
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.049"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            177..494
                     /locus_tag="VYN15_001601"
     CDS             177..494
                     /locus_tag="VYN15_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV1452899.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(644..1456)
                     /gene="folK"
                     /locus_tag="VYN15_001602"
     CDS             complement(644..1456)
                     /gene="folK"
                     /locus_tag="VYN15_001602"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV1452900.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(1499..2053)
                     /gene="folE"
                     /locus_tag="VYN15_001603"
     CDS             complement(1499..2053)
                     /gene="folE"
                     /locus_tag="VYN15_001603"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV1452901.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVIIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(2034..3356)
                     /locus_tag="VYN15_001604"
     CDS             complement(2034..3356)
                     /locus_tag="VYN15_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1452902.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDSPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(3358..4332)
                     /gene="folP"
                     /locus_tag="VYN15_001605"
     CDS             complement(3358..4332)
                     /gene="folP"
                     /locus_tag="VYN15_001605"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV1452903.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFNQTFTVEELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(4427..5134)
                     /locus_tag="VYN15_001606"
     CDS             complement(4427..5134)
                     /locus_tag="VYN15_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1452904.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(5187..6605)
                     /locus_tag="VYN15_001607"
     CDS             complement(5187..6605)
                     /locus_tag="VYN15_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV1452905.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            6795..7607
                     /locus_tag="VYN15_001608"
     CDS             6795..7607
                     /locus_tag="VYN15_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1452906.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            7946..8965
                     /gene="adhP"
                     /locus_tag="VYN15_001609"
     CDS             7946..8965
                     /gene="adhP"
                     /locus_tag="VYN15_001609"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV1452907.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSETMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            9198..10187
                     /gene="manX"
                     /locus_tag="VYN15_001610"
     CDS             9198..10187
                     /gene="manX"
                     /locus_tag="VYN15_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV1452908.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            10215..11018
                     /locus_tag="VYN15_001611"
     CDS             10215..11018
                     /locus_tag="VYN15_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV1452909.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            11042..11953
                     /locus_tag="VYN15_001612"
     CDS             11042..11953
                     /locus_tag="VYN15_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1452910.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(12009..13343)
                     /gene="pepC"
                     /locus_tag="VYN15_001613"
     CDS             complement(12009..13343)
                     /gene="pepC"
                     /locus_tag="VYN15_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV1452911.1"
                     /translation="MNAIQESFTNKLFANYEANVKYKAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQTKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
BASE COUNT         3897 a         3011 c         2680 g         3854 t
ORIGIN      
        1 taactgaaag ttatataatc aagttaattt gggaatttac ctattaactt cggtagattt
       61 ttgggaattt ttttccttct ttttccctgt agttaaaatc cttttcaaaa aatcaccttt
      121 tcttgatttt taatcctatt tgctgtatga taagggaaaa gaaaggggac agagatatgg
      181 cttttaccaa tactcacatg cggtctgcta gttttggcat tgttaccagc ttgcctgatg
      241 acatcattga ctctttttgg tatattatcg accatttctt aaaaaatgtc tttgaattgg
      301 aagaagaact cgagtttcaa ttgcttaata accaaggaaa gattaccttc cacttttcaa
      361 gtcaacacct ccctacagcc attgattttg actttaacca tcctttcgac cctcgttatc
      421 ccccaagagt actggtttta gacatggacg gtagagaaac tatcctcctc ccagaagaaa
      481 atgacctatt ttaatactca atgaaaatca aagagcaaac taggaagcta gccgcaagct
      541 gtacttgagt acggtaaggc gacgctgacg tggtttgaag agattttcga agagtataaa
      601 aactctagcc ttcagttgca agtgactgaa aactagagtt tttctatttt ttcaaagcat
      661 catacaagtt gcggatcggt tgttttaata tcggatggat aaaatgaggc gcaatttcct
      721 gtaaggactc aaggacaaaa aggcgttccg ctatgtaagg atgaggcaat atgaggtcgt
      781 ctgtataaag gatctggtcc tccacaaaga gcaagtccaa atcaatcaaa cgaggtcccc
      841 aatgcacttc tctcacccgt cccagctctg actcaatggc taacaaggtt tctaacaagt
      901 cttgtgctgg tagccaggtt tccacctcaa ccacttgatt ggcaaagcta tcctgctcca
      961 ctccacccca aggctccgtc gctaagacac tggactcttt gagaatatgg atgccacgag
     1021 ctcgcagttt gtcaatggct tgcttcaagt ttgcttgctt atctcccata ttgcttccta
     1081 gggcgataaa ggctcgttgc ttgcggcgat gaatggttac cgagcaagta tctagtgaca
     1141 aatgcaccgg tgcccaaggt tttttcagtt ccaacttcat ttcttggaca agaggataag
     1201 actcaaaggt acgttccacc agtttatagg ctaccgtttc aatcaaatct tcactcgttt
     1261 cctgaaacca agtcgtccac tgctgacaca attctccgta atggacagag gctgttaaat
     1321 ccaagtctgt agctgccttg gtcatatcat aggataggat ggctgaaacg acaaatttct
     1381 gccccaattc tttctcacta ggaaaaagac catgataggc aaacatttcc aaatccttaa
     1441 tctgcagttg atccataatg attcctttct agaaaaatcc gcttgaaacg gattcttttt
     1501 atagccccat taaacgataa gcttggtcgc ggaggtcctt atctgtttca aatagaccac
     1561 gagctactgt cgtcaaggtt gcagtgcctg gttttctaac accacgcata ctcatacaca
     1621 tatgttccgc ctcaatgata acaaaggctc ctttagcacc tagatagtcc atcaaggcat
     1681 cggccacttc gatattcaaa cgttcttgaa tttgtggttt tttcgaataa acttcaaccg
     1741 tacgggctaa cttagacaag cctgccacac gaccatctgg aatgtaggca atgtgcgctc
     1801 taccataaaa tggcaagaag tggtgttcac acatggtatg gaaaaagata tccttttcta
     1861 ccaccatatt atcgtcaata atttcaaagg attttgacaa atgttcctct gctgtttgac
     1921 caagacctga aaaaatctct tgatacatac gggctacacg agcaggtgtt tcctgcaaac
     1981 cctcgcgatt agcgtcctct cctacagcct cgataatcat ttttacagct gcttcaatct
     2041 tttgtgtatc cattctcgtt cttcctctcc atcagatagg ccctcacttg gctcaagaaa
     2101 tacaaggaac ctgtgacaat cctaactgtt tgtttctctt cttttttatc tgtcaaattc
     2161 tgctctagaa aatcatgcca atcttggtag ctgagatttc tagacttagc tgcctctttc
     2221 agcacgcttt catccgtcgc ccgactatcc gcaaaatgtg ttagagtaag ctcggtatct
     2281 ggcatggctc ccagcaagtc caacatatcc tccaaggcct tggttttgat acaagtgaag
     2341 aggatttcct tatgataatc cgcaaaacgt tcttgcaagg ttaccaacaa ggccttgata
     2401 gcatggggat tgtgggctcc atccaaaatc atcaagggat ctcttgacac gatttccaaa
     2461 cgccctggcc aacttgtttc ttccaaggct tgaccaagaa agtcattgct tgctagctct
     2521 cgaccatctt cttgacaaaa agtatcaagt aaagctatgg ccatcccagc attctctatt
     2581 tggtacaaac caagcaggct agtctggaag cgaccttgtc tgacagcact tgtatagtca
     2641 aagacttccc ctgtcaccac actttcttga tgacgaacct gataatctgt cccgtaggca
     2701 agtctcggcg aatctttccc ttccgcaatg cggtcaatca cagtcaaggc ttctggagca
     2761 atacgccctg ttaccaaggg catcccttgt ttgataatac ctgccttctg ctctgctatg
     2821 gcctccaagg tgtcaccaag tagggccaca tgatccaagc caatagttgt aattcctgtc
     2881 aaaatgggct gacagacatt ggtactatcc aaaagtccac ccatgccaac ttccatgatg
     2941 gccacatcta cttgctctga ggcaaagtag tcataggcca gggctgtgat aatctcaaac
     3001 tcggttgtgc cctgtaaatt ggcgaccgct tctccctcca gcaaagactg atagtctgcc
     3061 atgagagctt ctagcctcgc ttctgagatc gattccccat tgatgctaat ctggtctgtg
     3121 taatgaatga gatagggcga gctaaacacg ccaactctca gccctagctt ttctagcatc
     3181 tttttcaaaa aagcaatagt cgagcccttg ccgttagtcc ctccgatatg gaggaccttg
     3241 agtttgagat ggggattgcc acgcaaagct aacagttcca ccattcgttc caagccaaaa
     3301 tgcggttgat ccgtccggta gttagcaatc cactgattgt tttcaatttc tttcatctta
     3361 tttatattgc tttaaatcta aattttccgc ttcatcagcc agacgaatgg cagatgcaat
     3421 ttcaactgcc atcctgtgac tagctacgtc atgcacgcgc accacttcta caccctgtct
     3481 cgcagcgata ctagttacat gagccgaagc cgtgtcccga tttcggaaac caagctctgt
     3541 ctcaggattg acttcaaacc cactttcttc aaggatattg atgacaaatc gcttgcgcga
     3601 cactccgaga aagattggat agcccttctg atgtagttta tccagatccc gtaaaaggag
     3661 gagattttct ttcttggtca gaccaaagcc aattcctgga tccaacagga tattttctgg
     3721 tgcaatacca gcttctgccg ctctcgctag tgctcgttca aagaaagcca ccatcaagtc
     3781 ttcgattggc aatgtttcaa agtcagctaa ctcttctact gtaaaagttt gattaaatcc
     3841 aaaatgaggg aatatgagcg agctagggtg ttgaggtcgc gccataactg gattaaacat
     3901 gatgaccact tgcgctctcg cttcagctac cacatgagcc attttttcat cgcccatgag
     3961 accagtgata tcattaacta gattggcacc agcagccaaa gcagcctctg ctacttgact
     4021 cttccaagta tcaatagaga tgaggacatc actttccttg cgaatcgctt tgatcactgg
     4081 aacaacacgc tggatttcct cttctatctc aacatagcta ctgcccggcc gagtcgattc
     4141 tccgccgata tcgagcatac tggctccttc tgctatcaat ttacgagcct gctggagtgc
     4201 ctgctcaaga gcaaaaaatt gaccaccgtc cgaaaaggag tctggggtta cattgataat
     4261 tccgcaaata actgtctttg catgattggc tttacttgac atatcggtca ctccctcaag
     4321 gattttcatc atattatttt tctattttac cataaaaaga aaaagatgga cacgattgca
     4381 ttcatctttc cctagtggaa agaggtcggt tcctacataa aaacttttaa acagaaattc
     4441 ctaatgtccg actcataatc accacaagag ccaacaaaca gaaagcaatc ccattaacaa
     4501 tcatgtgaag caagatcgac atttccaaac gttgggtctt gtaggccgtc caagatagaa
     4561 ctgtcgacat acctccataa atcaataaag aaggtaaatt acttggttga tgcaataaag
     4621 caaacacaat cgtaccgact acaaatccca agttctcctt gcctcggaaa atctttttag
     4681 gaacaatccc acggcacaag atttcctcac aaatcggagc aagcaaggct agcaagaaga
     4741 aactggaaat caacgaacta ttttgaacca tatcgttaat ctgagactgg ttagctgttg
     4801 tcgtctcatt tgacagttgc aacaagatag aaccaagtat atttgacccg acaataacta
     4861 aataactcaa gcccaaacgt gccaaatctt tagctctaaa aaaagaaaaa ttaaaactag
     4921 ctaacttggt tttacgagct cccataataa atagagccag aaccacaatt gaaaggccag
     4981 caactatcag ccctgactgt agcagggcta cttcttttaa agtcaaaata gaggtaacca
     5041 ctaggggaac ctgatataaa aggacggcaa gtaaaaagac caaaatccag cctgcacgat
     5101 tcaacaattc tttccacata tttttctctt tcatcaccta tctcctttgt attaaaaaag
     5161 gggggaaatc cccctgggtc attctattat aaggccatgc tgatgtagtt aaggataaac
     5221 aaggcatcca aaatccaaat catggcatga acatctttaa cttgaccttt gacaagctta
     5281 gtcaaagtgt aagtcaagaa accaactgca atcccttgag tgatagagta gctgaatccc
     5341 ataaagatag atgtgaagaa ggcaggaact gcttcagaca tatcatccca atggatattt
     5401 ttcaagctac caagcatcat aatcccaacg ataatcaaga ttggagctgt agccgctgtt
     5461 ggtacgatcg ctagaagtgg gctaaagaag cttgaaatcg caaaacagat agctacaacc
     5521 aaggctgtca aaccagtacg tccacctgca ccgataccag cagcagactc aacataagtc
     5581 gttacgtttg aagtacctgc aatggcaccg actgtcgttc caatcaaatc agagtaaaga
     5641 gccttatcca atttggctga ttggtgattt tcaccatttg tcgctacaat accaactttt
     5701 tcacctgtac cgatcaaggt accaattgtg tcaaaaatat ctgtcaatga gaaggcaaga
     5761 atggccatca gagtttcagg caagcgagct gtatctgaaa ccaaagctcc caatccttct
     5821 gaaccaagag ctgcaccaaa gattgtcttc aaatcttcaa aagctgcacc aacatggtta
     5881 ttagcaaaat cgatactaga caaatcaacc aaaccaactg caatagcaag aacagttgtt
     5941 gtcaagatag agagaataat tcccccttta atccctttga tgacaaagaa gatagtaatg
     6001 gcaagtcctg caagagccac taaaacagct ggattattaa agctgaccaa tcctggaact
     6061 gctgaagagt ttgctgcaat cgttgcttga gctttgtcag ccccttctcc tacaacagta
     6121 tagttgcctg gatcaatcgt gaatttcaaa agtccagcat tcttaatccc tacataggca
     6181 aggaagacac cgataccagc tgaaatagct gagcgaagag cattgggaat cgattcaatg
     6241 atcattttac gaacatttgt caaggtaata atcaatgaaa taatcccaca gatgaagacc
     6301 atagctaggg cttcttgcca agaataacca agcccgaata caactgtaaa ggtaaagaag
     6361 gcattgagtc ccatacctgg cgcttgggca taaggtaagt tagcataaaa agccatcatc
     6421 aaggtacccg ctactgcacc aataatcgtc gctaggaaga cgccctgagc aggcattcct
     6481 gtttgtgaaa gtatttgtgg gtttacaaag agaatatagc tcattgcaaa gaaagttgtt
     6541 aaaccagcga gaacctctgt acgaacgtct gtaccgttct cttttagttt aaataatttg
     6601 tccatcatca atctcctttt aatttttacg aacaataata gaattatatc atttatcatt
     6661 cactttttca atgtctttgt ttgatttgtt taagaaatta atccaatttc attttttgtt
     6721 tggaatctgc ttttctgcct gctttctgtt ataatagaag acatcttatc tgaaaacaca
     6781 ctagaaaggt ccatatgacg aaaaaaatta ttgcagttga cctggatgga accctgctca
     6841 actcagacag tcaaatttct gactttacca aaagaaccat caaaaaagtt gctgaaaaag
     6901 gccatcaggt tattattacg acaggtcgcc cttaccgtat gtcaaaagat ttttaccgtg
     6961 aactgggctt agacactcct atgattaact tcaacggatc ccttactcat ttaccagacc
     7021 aagtttggga ttttgaaaag tgtttgactg tagacaaaaa atatctgcta gatatggttc
     7081 aacgttcaga ggacattcaa gccgatttta tcgctggaga atatcgtaaa aaattctaca
     7141 ttacaaatcc caatgaagaa attgccaatc ccaaactatt tggtgtagaa gctttccagc
     7201 ctgaagatca attccagcct gaattggtga ccaaggaccc taactgtatc ctcttgcaga
     7261 ccagagccag tgacaaatat gccttggcaa aagaaatgaa cgccttctac cagcatcaac
     7321 tttctatcaa tacctgggga ggtccgctca atatccttga atgtacccca aaaggtgtca
     7381 acaaggcctt tgctttggac tacttgctca agataatgaa tcgtgacaaa aaagatttga
     7441 ttgcctttgg agatgaacac aatgataccg aaatgctcgc ttttgctggg aagggttatg
     7501 ccatgaaaaa tgccaatcca gagctactcc cttatgcaga tgagcaaatt tcccttacca
     7561 acgaccaaga tggggttgcc aaaaccctac aagacttatt cttataacct atactgatac
     7621 tcaatgagaa tcaaagagca aactaggaag ctagccgtag gttgctcaaa gcactgcttt
     7681 gaggttgtag atgaagctga cgtggtttga agagattttc gaagagtatg accagcttgc
     7741 aagctggtct ttgtgctctt ttcacagtct catcaaccag ttaatcgatt gttctacttt
     7801 ttgtctccaa aaccttggaa aaggctttct tttgtgatat acttcacata taaatacaag
     7861 agagctcgtc acactcgact ctgttgacaa aaaatcaatc cagtcccgtt gtccctgttc
     7921 tcggtcaata tcaaggagga tagctatgaa agctgttgtt gtaaatccag aaagcactgg
     7981 tgttgctatt gaagaaaaag tactccgtcc acttgaaact ggggaagcac ttgtagaagt
     8041 tgaatactgt ggtgtttgcc acaccgacct ccacgttgct catggtgact ttggtcaagt
     8101 cccaggacgt gttcttgggc acgaaggtat cggtatcgtt aaagagattg ctccagatgt
     8161 gaaaagcctt aaagtcggtg accgcgtcag cgttgcttgg ttctttgaag gatgtggcac
     8221 ttgcgaatac tgtacaactg gtcgcgaaac cctttgccgt acagtgaaaa atgctggcta
     8281 ctcagtagac ggtggtatgg ctgaacaatg tatcgtaact gctgactatg ctgtcaaagt
     8341 tcctgacgga cttgatccag cccaagcttc ttctatcaca tgtgctggag taacaaccta
     8401 taaagctatc aaagaagcaa aagttgaacc aggccaatgg gttgttcttt acggtgctgg
     8461 tggacttggt aacctcgctg ttcaatacgc taaaaaagta ttcaatgctc atgttatcgc
     8521 agtcgatatc aacaatgaca aacttgccct tgcaaaagaa gtaggcgctg acattgtgat
     8581 taacggcctc gaagttgaag atgtagctgg actcattaaa gaaaaaactg atggaggagc
     8641 tcattcagct gtcgtaactg ctgtgtctaa agttgccttc aaccaggctg ttgactccat
     8701 tcgtgctggt ggtcgcgtcg tcgctgttgg tcttccttct gaaacgatgg aactcagcat
     8761 cgttaaaaca gtcctcgatg gaatccaagt catcggttct cttgtcggaa ctcgtaaaga
     8821 cttagaagaa gccttccaat ttggtgcaga aggtctggta gtcccagttg ttcaaaaacg
     8881 tccagtagaa gatgctgttg ccattttcga cgaaatggaa aaaggccaaa tccaaggacg
     8941 tatggtactc gacttcaccc actaatctaa tagaaaccta ttttaaaagt tggaagcttc
     9001 ttccaacttt tttatattaa attttaaata agaattcaag attactcctc aaaaactcaa
     9061 catatcaaca tacaaaaata aaaatttttt aattttttat gataaatagt tgcttttttt
     9121 atgaaaacgg tttatactta aacagtctta aagttttctt aaatgaaaac taaaacaaaa
     9181 aaggaggaat gacaataatg agtatcggaa tcattattgc gagccacggc gaatttgctg
     9241 cgggtattca tcagtcagga tctatgatct ttggtgaaca agaaaaggtt caagttgtga
     9301 cctttatgcc aaatgaaggt cctgatgatc tatacgctaa gtttaataac gctgttgctg
     9361 catttgacgc agaagatgag gttctagttt tggctgacct ttggagtggt tctccattta
     9421 accaagctag tcgcgtgatg ggagaaaatc ctgagcgtaa gtttgccatc atcacaggac
     9481 ttaacttacc gatgttgatt caagcctaca cagagcgcct catggacgct gctgcaggtg
     9541 tagaaaaagt cgctgctaat atcattaaag aagccaaaga tggcatcaaa gctcttccag
     9601 aagagctaaa tccagttgaa gaagttgcaa gcgctgcagc tgctccagtt gcccaaactg
     9661 ctatcccaga aggaactgtt atcggagacg gtaaattgaa aatcaatctt gcccgtcttg
     9721 acacacgact acttcacggt caggttgcaa ctgcttggac tccagattca aaagcaaatc
     9781 gtatcatcgt tgcttcagat aacgtggcta aagacgacct tcgtaaagaa ttgattaaac
     9841 aagcagctcc aggtaatgtc aaggctaacg tggttccaat tcaaaaactg attgagattt
     9901 caaaagaccc acgttttgga gaaacacatg cccttatctt gtttgaaaca cctcaagatg
     9961 cccttcgtgc catcgaaggc ggcgtgccaa tcaagactct taacgttggt tctatggctc
    10021 actcaacagg taaaacattg gtcaataccg ttttgtctat ggacaaagaa gatgttgcta
    10081 catttgaaaa aatgcgtgac ttgggtgttg aatttgatgt ccgtaaagta ccaaatgatt
    10141 ctaaaaaaga tttgtttgac ttgattaaca aagccaatgt caaataagcc attatttatg
    10201 aaaggatttt aaacatgtct attatttcta tggttttagt agtcgttgta gccttctttg
    10261 caggtcttga aggcatcctc gaccagttcc aatttcacca accacttgta gcctgtaccc
    10321 ttattgggct tgtaacaggt cacttggaag cagggattat cctcggtgga tcgcttcaaa
    10381 tgattgccct tggttggtca aatatcggtg ctgctatcgc tcctgatgct gcacttgctt
    10441 ctgtcgctgc tgccattatc atggttcttg gtggtgactt taccaagact ggtatcggtg
    10501 ttgcccaagc ggttgctatc cctcttgccg tagctggact tttcttgaca atgattgttc
    10561 gtacaatttc agttggtttg gttcatactg cagatgctgc cgctaaaaaa ggtgacttcg
    10621 gcgctgtgga gcgtgcgcat ttcattgcgc tacttttcca aggacttcgt atcgcgcttc
    10681 ctgcagctct tctccttatg gtaccaactg aaactgtaca aagtatcctt agtgccatgc
    10741 cagactggct caaagatggt atggctatcg gtggtggtat ggtcgttgcc gttggttacg
    10801 ccatggttat caacatgatg gcaactcgtg aagtatggcc attcttcgct cttggtttcg
    10861 ttctcgctgc tgtgtcagat attactctaa tcggattcgg tgctatcggt gttgctatcg
    10921 ctcttatcta ccttcacctt tctaaaactg gtggaaatgg tggcggagga gccgcaactt
    10981 ctaacgaccc aatcggcgat atcctagaag actactaaga taagaaagga ctgaaaacat
    11041 catgactgaa aaacttcaat taactaaatc agatcgtaaa aaagtttggt ggcgttcaac
    11101 cttcttacaa gggtcttgga actttgaacg gatgcaaaac ttgggctggg cttatacact
    11161 cattccagct atcaaaaaac tctatactaa aaaagaagat caaatcgctg ctcttgagcg
    11221 tcaccttgag ttcttcaaca ctcatccata cgtagctgct ccagtcatgg gggttactct
    11281 tgcgcttgaa gaagaacgtg ctaacggtgt ggaaatcgat gacgctgcta tccaaggggt
    11341 taaaatcggt atgatgggac ctcttgctgg tatcggtgac ccagtattct ggtttacagt
    11401 acgcccaatc cttggatctc tcggtgcttc acttgccctt actggcaata tcttggggcc
    11461 actcctcttc tttgttgcat ggaacttgat tcgtatgtca ttcttgtggt atgttcaaga
    11521 gattggatac aaggctggat cagaaatcac taaagatatg tctggtggta tccttcaaga
    11581 tatcactaaa ggagcttcta tccttgggat gttcattctt gctgtccttg ttcaacgctg
    11641 ggtaaatatt aaatttgctt tcgatgtttc taaagttcaa ctagatgaaa aggcttatat
    11701 ccattgggat aaattgccag aagggtctaa aggtatccaa gaagcattcg cacaagtagg
    11761 acaaggattg tctcaaactc ctgaaaaagt tactactttc caacaaaact tggatatgtt
    11821 gattcctgga ttatcaggac tactccttac tttactttgc atgtacttac ttaagaaaaa
    11881 agtatctcca atcactatta tccttgccct cttcgcagtg ggtattgtgg cacatgttct
    11941 tcacatcatg taatcaagca actaaaaagg aaccaggttc taaaatctga ttcctttttt
    12001 ctatgctttt attcagccaa ggctcccatt ggatcccatg gtgcaagtac gattggttct
    12061 gctccatagg cagcttgttc ttctgctgtc agcaattcct tacgaacaac gatttggtat
    12121 gtgtattcgt ccatccaagc gtctgaggca acaaagtaac catctgtacc gaccttgtct
    12181 ccccatgagt tttcaacctt ccacttggtt gatttaccat tttcgtccaa gtcaacacct
    12241 gtcaagacca tggcgtgggt catcaagctt tcgctatagt ccaaacgtcc agccttgtct
    12301 tgagtaagtt taatgtccat gcttgattca aagtcataaa catctgtcgc aaggatgcca
    12361 gccttacggt tgctgagctg gccgacatca gaaccaaacc aaacagtctc acctgcttgc
    12421 atttgggcaa tcgccaattc tttcaagcgc tccattggaa cgttgatgta gcgaactgca
    12481 cggctaccaa caacattccc caacatctca actgtgtaag attttccgta aggtttatca
    12541 gcagttggag cattgataac agaaacgtag tcttctaaag gaagattgac atatttcttg
    12601 taaaactctt gtggtgtgat tcctttttca cttttgtagt tgttatcttt atcgcgataa
    12661 gcaaagtcaa acttgcgtgg tggaagtcct aatgacatag caagaaagtt aaagatttct
    12721 tgcaagaggt cttctttctt agtttgaaca gtcgcttgat ctgcaccaga aacaagcaaa
    12781 tcacgcaaga tttgagcatc ttgacgaagc aatttattaa ggatcgcatt tagctcacga
    12841 ctgctgctag atgaaacaga ctcaggataa actgacttag gcacgacacc gtatttttca
    12901 aagagggaaa cgaccatatc ccattgaccg ccatcttgtt gaggtgtttg gagtaagaag
    12961 ctaaccttgc ggctagtcaa ttcttggtct gaagtcgcaa tgacttgctc caagaaccag
    13021 tttgatttct catacttatc ccagaagaaa gtgtgggctt gtgacaactc aaagttctcc
    13081 aatttgtatt gcgagatgag tttgtggcgg aaggtgttga gagccgcaaa catccagcaa
    13141 cgaccagacg ctttctggtt agtgaccttg tccttggtta aatccaatga gaaaacaggt
    13201 gtgttgtcta catggctttg gcgacattcc agagctgcaa aaattccgtt gtggctggca
    13261 gcattttcaa tcgctttgta ttttacattt gcttcatagt tggcaaatag tttattagta
    13321 aatgattctt gaatcgcgtt catagattcc tccttttatt ctacagtcta ttataactct
    13381 tttcacaaag gaagcaacta aaaaacataa aaggtaagga cattctccct cacctttttc
    13441 ga
//
LOCUS       DAVLTT010000050        13211 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLTT010000050 DAVLTT010000000
VERSION     DAVLTT010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13211
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.050"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            124..2289
                     /locus_tag="VYN15_001614"
     CDS             124..2289
                     /locus_tag="VYN15_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1452912.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKVKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIS"
     gene            2289..3029
                     /locus_tag="VYN15_001615"
     CDS             2289..3029
                     /locus_tag="VYN15_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1452913.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            3178..4665
                     /locus_tag="VYN15_001616"
     CDS             3178..4665
                     /locus_tag="VYN15_001616"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV1452914.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHINIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(4711..5988)
                     /gene="ftsY"
                     /locus_tag="VYN15_001617"
     CDS             complement(4711..5988)
                     /gene="ftsY"
                     /locus_tag="VYN15_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV1452915.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLESVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(5992..6810)
                     /locus_tag="VYN15_001618"
     CDS             complement(5992..6810)
                     /locus_tag="VYN15_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1452916.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            complement(6810..7604)
                     /locus_tag="VYN15_001619"
     CDS             complement(6810..7604)
                     /locus_tag="VYN15_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1452917.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            complement(7601..11140)
                     /gene="smc"
                     /locus_tag="VYN15_001620"
     CDS             complement(7601..11140)
                     /gene="smc"
                     /locus_tag="VYN15_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV1452918.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLREIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELTQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLEEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAASAGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARKVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLGSEEVALKTLQDQMARLTESLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSDGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNFQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLSLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            complement(11131..11829)
                     /locus_tag="VYN15_001621"
     CDS             complement(11131..11829)
                     /locus_tag="VYN15_001621"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV1452919.1"
                     /translation="MKELQTVLKNHFEIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            complement(12012..12083)
                     /locus_tag="VYN15_001622"
     tRNA            complement(12012..12083)
                     /locus_tag="VYN15_001622"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12048..12050),aa:Arg,seq:ccg)
     gene            complement(12147..13133)
                     /locus_tag="VYN15_001623"
     CDS             complement(12147..13133)
                     /locus_tag="VYN15_001623"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV1452920.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
BASE COUNT         3756 a         3022 c         2426 g         4007 t
ORIGIN      
        1 atagcaattc aagaaagaaa aggaaaaatc aatgttatat tttctgacac taaaaatata
       61 acaatttgcc tttttttact ttttctgata taatgagaga atattcggaa aaggagacta
      121 aaaatgaaga aaaaatttct agcatttttg ctaattttat tcccaatttt ctcattaggt
      181 attgccaaag cagaaacgat taagattgtt tctgataccg cctatgcacc ttttgagttt
      241 aaagattcag atcaaactta taaaggaatt gatgttgaca ttattaacaa agtcgctgag
      301 attaaaggct ggaacattca gatgtcctat cctggatttg acgcagcagt caatgcggtt
      361 caagctgggc aagccgacgc tatcatggca gggatgacaa agactaaaga acgtgaaaaa
      421 gtcttcacca tgtctgatac ttactatgat acaaaagttg tcattgctac tacaaagtca
      481 cacaaaatta gcaagtacga ccaattaact ggcaaaaccg ttggtgttaa aaacggaact
      541 gccgctcaac gtttccttga aacaatcaaa gataaatacg gctttactat taaaacattt
      601 gacactggtg atttaatgaa caacagcttg agtgctggtg ccatcgatgc catgatggat
      661 gacaaacctg ttatcgaata tgccattaac caaggtcaag acctccatat tgaaatggat
      721 ggtgaagctg taggaagttt tgctttcggt gtgaaaaaag gaagtaaata cgagcacctg
      781 gttactgaat ttaaccaagc cttgtctgaa atgaaaaaag atggtagtct tgataaaatt
      841 atcaagaaat ggactgcttc atcatcttca gcagtgccaa ctacaactac tctcgcagga
      901 ttaaaagcta ttcctgttaa ggttaaatat atcattgcca gcgattcttc ttttgcacct
      961 tttgttttcc aaaattcaag caaccaatac actggtattg atatggaatt gattaaggca
     1021 atcgctaaag accaaggttt tgaaattgaa atcaccaacc ctggttttga tgctgctatc
     1081 agtgctgtcc aagctggtca agccgatggt atcattgctg gtatgtctgt cacagatgct
     1141 cgtaaggcaa cttttgactt ctcagaatca tactacactg ctaataccat tcttggtgtc
     1201 aaagaatcaa gcaatattgc ttcttatgaa gatctaaaag gaaagacagt cggtgttaaa
     1261 aacggtactg cttctcaaac cttcctaaca gaaaatcaaa gcaaatacgg ttacaaaatc
     1321 aaaacctttg ctgatggttc ttcaatgtat gacagtttaa acactggtgc cattgatgcc
     1381 gttatggatg atgaacctgt tctcaaatat tctatcagcc aaggtcaaaa attgaaaact
     1441 ccaatctctg gaactccaat cggtgaaaca gcctttgccg ttaaaaaagg agcaaatcca
     1501 gaactgattg aaatgttcaa caacggactt gcaaacctta aagcaaacgg tgaattccaa
     1561 aagattcttg acaaatacct agctagcgaa tcttcaactg cttcaacaag tactgttgac
     1621 gaaacaacgc tctggggctt gcttcaaaac aactacaaac aactccttag cggtcttggt
     1681 atcactcttg ctctagctct tatctcattt gctattgcca ttgtcatcgg aattatcttc
     1741 ggtatgttta gcgttagccc atacaaatct cttcgcgtca tctctgagat tttcgttgac
     1801 gttattcgtg gtattccatt gatgattctt gcagccttca tcttctgggg aattccaaac
     1861 ttcatcgagt ctatcacagg ccaacaaagc ccaattaacg actttgtagc tggaaccatt
     1921 gccctctcac tcaatgcggc tgcttatatc gctgaaatcg ttcgtggtgg tattcaggcc
     1981 gttccagttg gccaaatgga agccagccga agcttgggta tctcttatgg aaaaaccatg
     2041 cgtaagatta tcttgccaca agcaactaaa ttgatgttgc caaactttgt caaccaattc
     2101 gttatcgctc ttaaagatac aactatcgta tctgctatcg gtcttgttga actcttccaa
     2161 actggtaaga ttatcattgc tcgtaactac caaagtttca agatgtatgc aatccttgct
     2221 atcttctatc ttgtaattat cacacttttg actagactag cgaaacgctt agaaaagagg
     2281 attagttaat ggcaaaatta aaaattgatg taaatgattt acacaagcac tatggaaaaa
     2341 atgaagtcct aaaaggaatt acgactaagt tctatgaagg agatgttgtt tgtatcatcg
     2401 gtccttcagg ttctggtaag tcaactttcc tccgtagcct caatctttta gaagaagtca
     2461 ctagcggtca catcactgtg aacggctatg atttaactga aaaaacaacc aatgttgacc
     2521 acgtccgtga aaatatcggc atggtattcc aacacttcaa cctcttccct catatgtctg
     2581 tattggacaa catcaccttt gctcctattg agcacaagtt gatgactaag gaagaagctg
     2641 agaaattggg aatggagttg cttgaaaagg ttggactagc agataaagct aatgccaatc
     2701 cagatagcct atcaggtggt caaaaacaac gtgtggccat agctcgtggc ctagcaatga
     2761 atccagacat catgctcttc gatgaaccaa cttctgccct tgaccctgag atggttggag
     2821 acgtacttaa cgttatgaag gaattggctg agcaaggcat gaccatgatt atcgtaaccc
     2881 atgagatggg atttgctcgt caggttgcca accgcgttat ctttactgca gatggcgagt
     2941 tccttgaaga cggaacacct gaccaaatct ttgataaccc acaacaccct cgtctgaaag
     3001 agttcttaga taaggtctta aacgtctaaa ctcaaactgt aaggatttcc ttgcagtttt
     3061 tctacctcgt attggaattt ttgatttttc ggaaaattat gttagaatta agtttatgaa
     3121 atgaggtttc ctcataccta gcaagactag gaataaaaat agaaattagg tagctagatg
     3181 tcatctaagg ttattgttac aattttcggt gcgagtggag acctggctaa acgcaagctc
     3241 tacccttccc tttttagact atataaatcc ggcaatcttt ccaagcactt tgccgttatt
     3301 ggaactgccc gtagaccttg gagtaaggaa tattttgaat ctgtagttgt cgagtccatc
     3361 cttgatttgg cagatagtac cgagcaagcc caagaatttg ctagccactt ctactatcaa
     3421 agccatgatg tcaatgattc ggaacattat attgctttgc gtcaattaca agctgagctt
     3481 aatgaaaaat accaagctga acacaataag ctcttcttct tgtctatggc acctcagttc
     3541 tttggaacca ttgccaaaca cctcaaatct gaaaacattg tcgatggcaa aggttttgag
     3601 cgcttgatcg ttgaaaaacc atttggtaca gattacgcaa ctgcaaacaa gttgaatgac
     3661 gaactcctag caacatttga cgaagaacaa attttccgta tcgaccatta tcttggtaag
     3721 gaaatgatcc aaagcatctt tgcagttcgc tttgcaaact tgatttttga aaacgtttgg
     3781 aacaaggatt ttatcgacaa tgttcaaatt acctttgcgg agcgcttggg tgtagaagaa
     3841 cgtggtggct actatgacca atccggtgcc ctccgtgaca tggtccaaaa ccacactcta
     3901 caacttcttt cgctcctcgc catggacaaa ccagcaagct tcacaaaaga cgagattcgt
     3961 gctgaaaaga ttaaggtctt taaaaacctc tatcatccaa ctgatgaaga actcaaagaa
     4021 cactttatcc gtgggcaata ccgctctggt aagattgatg gcatgaaata catctcttat
     4081 cgtagcgagc caaatgtgaa tccagaatca acaactgaaa cctttacatc tggtgccttc
     4141 tttgtagaca gcgatcgatt ccgtggtgtt cctttctttt tccgtacagg taaacgactg
     4201 actgaaaaag gaactcatat caacatcgtc tttaaacaaa tggattctat ctttggagaa
     4261 ccacttgctc caaatatttt gaccatctat attcaaccaa cagaaggctt ctctcttagc
     4321 ctaaatggga agcaagtagg agaagaattt aacttggctc ctaactcact tgattaccgt
     4381 acagatgcga ctgcaactgg tgcttctcca gaaccatacg aaaaattgat ttatgatgtc
     4441 ctaaataaca actcaactaa ctttagccac tgggatgaag tttgtgcgtc atggaagttg
     4501 attgaccgta ttgaaaagct ctgggctgaa aatggtgccc cacttcatga ctataaagct
     4561 ggaagcatgg gacctcaagc cagctttgac ctacttgaaa aattcggtgc caaatggact
     4621 tggcaaccag atatcaccta tcgtcaagat ggtcgcttag aataaaaaaa tttcctgcaa
     4681 gtttatgcct tgcaggattt ttgcttctga ttagattaaa ccttccaaga gacctttcat
     4741 aaagttttct gagttaaact ctccaatatc atcgattttt tcaccaaaac caatcaattt
     4801 tacaggaata ttgagttctt cacgaatggc tagaaccaca cctcctcgag cagttccatc
     4861 aatcttagtc aaaacaattc ccgttaaagg tgtgattttc gaaaattctt tggcctgtac
     4921 tagggcattt tgacctgttg atgcatcaag tgccaagaag gtttcatgtg gtgcttctgg
     4981 cacaacacgt ttgataatac gaccaatctt ttccaactca gccataaggt tatccttatt
     5041 ttgcagacga ccagcagtat caatcatgag aatatcgata ccttcagcca cggcacgttc
     5101 cataccatca aagaccacgc tggctggatc agctttttca ggtccagtta ctactggaac
     5161 atctactcgt cggccccatt cagctagctg agctactgca cccgcacgga aggtatctgc
     5221 tgcaaccagc atgaccttct taccagcttg tttgtagcgg tgggctagtt ttccgataga
     5281 agttgttttc ccaacaccat tcacaccaac aaagagcata actgtcaagt tatcttggaa
     5341 gtggatgctt tcatcgtagc taccatcctt ttcataaagc tcaaccaatt tctcaatgat
     5401 gacacgacga agtgcatcag gtttcttggc attttcaagc ttggcttcgt aacgtagttc
     5461 ctccgttaag ttagaagcga cttggacacc aacatcactc ataatcagca gttcttccag
     5521 ttcctcgaaa aattcttcgt caacagagcg gaagttagca aagaaggcat tcaagcgggc
     5581 accgaaacct gtacgagttt tcttaagact gcggtcatat ttttcctgaa cggtttcttc
     5641 tgcttgaggc ctttctggtt caagaacttc agaattattt tcttctatag tctctagaaa
     5701 ctcagtattc ccttcttctg agtgtggaaa ttcttcgact tctttttgag aaacttctac
     5761 aactgactct aaatccagac tttcttcaac tgtgtcttgg atttcctctt cttggaacac
     5821 agcttgttca acaatttcaa cctctgcttc ttcctgagaa acttcctcaa cttctgtgaa
     5881 ggtaggatca acatcttcag acaaatcaag attttccaga gcttctttta caacttcttc
     5941 gattttaggt tcttcttttt ttccgaatag acggtcaaac aatcccatat cttagttctc
     6001 ctttagcaca tattcttcga tagcccaggc gacagcttcc tcatcgttgg tcatcggcgt
     6061 cactacattt gcggctgcct ttacttcagg aacagcgttt tgcatagcaa caccaagacc
     6121 tgcccattca atcatagaga gatcattggc ctcgtcacca caagccatca cttgactttg
     6181 gtcgattcca agatggctga ttagttttgc caaacctgtt gctttatgaa cattctttgg
     6241 tgaccattct agcaacattt cacgtgattt aaagatttca tattggtcaa acaattctgg
     6301 agaaatcttc tgaatggctg catccaaggg ttcttgagca aaggcagtca cgcatttgtt
     6361 gtaggtcatt tgactagata agtcttcaaa gtccactgga acaaaggtca aagctggatt
     6421 gaatttggca taaagacttt cttggtccga ttggatttga taaactgttc cttctgagat
     6481 ggcatcaaga ggcagtgata atttctctgt ttcttcatac aaacgtgcca catcatcata
     6541 tgaaaagact gttttatcaa ggatttctcc tgtatttttc tgaactaatc caccattaaa
     6601 agtaatggta tactcatctt cctgaccgtc agtccctaac tcatggagaa agaaatccat
     6661 ggcttttaag ggacgaccag ttgtcaatac gaccttgata ccacgatcac gcgcagcttt
     6721 caaggtttcc ttggtacgat ccgtcagcct tttatcagta gtcagcaagg tcccgtccaa
     6781 gtccaatgca atcaatttta tatctgccat tataagccct ccatataagc tataaccgac
     6841 cgttccttat ggtgaccaat cacagtcttt gctaattcta aaatttcagg tcgtgcattt
     6901 tcaggagcta caggatgtcc cacaacctgc atcatatgta agtcattaag attgtctcca
     6961 aaagccatga cctgatccat tgtgatacca agttttttag ctaattcaac aatagctaca
     7021 cccttatcga catagtccag aacaatatca atagattcaa agccagttgt catggcctta
     7081 acaccaggga catgttcatt aacccaagct tcaccagctt ctagcgtttc ttctgtgaag
     7141 ttggttgtaa atttgaaaat gtcatctgtg atatcttcca aactcgctac tttttggata
     7201 ttttcattat aatgctgact cactttcaaa taggtctcat caaccgtatc tagaacatat
     7261 gaacccttct tacccgtcaa gagcagttta ttgatatcta cataaggtga cgtcttcagc
     7321 ttttcaaaag ttgccagata aaagtcacga gacatagtcg cttcatacaa gtcctgacct
     7381 tgatactcta ccaaactgcc attttccgcg atgaaaataa tgtcatcacg aacatcagca
     7441 aataattttt ccagagacag aaatccccga cccgaagcca ccgcaaagta aatccctttt
     7501 tccttgtagg aagccaagag agacttgaga cgatccatat caaagcgtcc attcccatct
     7561 aggaaggttc cgtccatatc cgttgctact agtttaattg tcatccttca atactttcta
     7621 aatcttttaa cttaactgaa acaatttttg agacacctga ttcttgcatg gtcactccat
     7681 agatagaatc agccgctgcc atggttccct tacggtgggt tacgacgata aactggctgt
     7741 ccttgtcaaa tcgattgagg taatccccaa aacgtttaac attggcttcg tccagcgcag
     7801 cctctacctc atccaagatg acaaatggga tagtcttaac tcgaatgata gaaaaaagca
     7861 aagcaagagc cgatagagct ttttcaccac cactcatgag gctaagagac tggattttct
     7921 tacctggagg ttgaacagaa atctccacac cagctgttaa aaggtcgccc tcagtcaata
     7981 tcaagtctgc ctgacctccg ccaaacatct gcttgaaggt cactttaaag gactcacgaa
     8041 tagcttcaaa ggttgattta aagcgttcct tgacctcatc attcatctct gtaatggttt
     8101 caaggagcag atttttcgct gacaaaatat catctcgctg actatttaga aagtccagac
     8161 ggttgtgaac ttcttcgtac tggtcaatag cttctatatt gacaggaccc agtgagcgaa
     8221 tagccttctc taaatcctta acttcttgct ctgccagatt gaggttttcc aattcatgcg
     8281 ctttttctag agcttcagta tagctaatct ggtactggtc tgttaattga ctttgtagat
     8341 ggcgcaagcg ctcgctgacc ttttctttct tggcttcagc acgtgtttgc ttgcgaatcc
     8401 actcctcatt ctgctggcga gcctgatcca aatgactagc aatatcatcc agctgacctt
     8461 ctatatcatc caactcaaac tgtttgcgaa tcaaaccttg ttggaagttc gttttctgag
     8521 ttttggattc ttccgcctgt tgactgagca attctgtatc aaccttctca agattgtcaa
     8581 ccttttcttg aagaaggcgc tggatttcct cttgttcaaa atcaagattg tccaattcct
     8641 tgcctaagcg ttcaatatca gccacttcat aacgtttttg cccttgcagt tctgtcttaa
     8701 gcaaacgagc ttgcgctagc tcttcctgca agttttgata gcgttcttgg atggcatttt
     8761 tgttagactt aatctcttca atctcagctt ccagattttg cttgtcactg gcgattgcag
     8821 caagacgctc ttggcagttt tccttgtctg cttgccaatc tccatcagaa agacgatcta
     8881 tttcctcttc ttggagtttc caaagagttt ccagttcttc aacttgctga ctagtttgct
     8941 gataagcgag ggacaagcct tgctcctgaa tacgtgcctg ctctccttga gatttaatag
     9001 cttctaatga ctcggtcaat ctggccatct ggtcttgcaa ggtcttcaaa gccacttctt
     9061 ctgaacccaa gcttgcttct tcttcagcaa tttctttttg taattgctcc agttctggct
     9121 tgatgaaaat actgttattc tgacgattgg ctccacctgc gtaagaacca cctgtgcgca
     9181 actctgtacc gtccaaagtc accatacgaa cctgataacg aactttgcgc gctgctgcac
     9241 gcgcatgctc aacggtatca aaaatcgctg tcgtagctag caagttcttg aaaatagctt
     9301 ccagtctcgt atcgaatgtc accaactcat ctgccatgcc tagaaatccc gcacttgcag
     9361 cgataacatc ttggttctga ctagaaatcg tacgcgcctt gatagtcgtc aacggaagga
     9421 aggttgcacg accagctcta tttcgtttga ggaaatcaat cgccttggtt gccgactctt
     9481 catcttctac gatgatatgc tgactgctgg ctccaagtgc aatctctaag gcagtttgat
     9541 aatgcacatc aaaggtcaaa tgctcactaa cagcaccaat aatcccacca aggcggtctt
     9601 tttcttggag aacactcttt acacctgcat aaaagttact gtgatttcta aggatgtttt
     9661 ccaaactttg agctctagcc tgcttgtttt taagactatc cagacggtca aagagttgac
     9721 tttgttgagc ttgataggaa gttttttgct cctcttgctc cttggcaata gcttgatagt
     9781 cagccaataa tttctgaacc tgctccttgg cagtttcaag ctcttccttt tgctgactag
     9841 ccttctcttt agctatagct aattgctctt ccagcttttc tagttgatct gcttgttttt
     9901 gagaaagctg acgactattt tccaactcat tctcaatacg ggtcaactgg tttgagacat
     9961 ccgcttcttc ttgtaaaaga gctacaaagc gttcacgtaa gagctcaatc atctgatcag
    10021 gatcgtctga gaaagccagc aattcagctt ctaaacgatt gagtttttga ttattttgga
    10081 ctagatttcc ctctaacaga gctaaagagc tttctttatc agacttttct ttgctgagtg
    10141 aatttctctt atcctccaaa gcagccaaac gggcttgtgc ctcctgttga ttcaaggcca
    10201 cttgctcgga ctccagtttc gatagggcta attttctttc taaatcacta atcagactag
    10261 tcaagtccat caaactgcct tggtctttgg ccatttcagc ctgtaaatct tggcgttgct
    10321 ttttaagagt ttgattttct tcttctaatt tttcacgctt ttggtaataa ctcatcaaga
    10381 gttcttgaac ctgagtcaac tcttcttctg tcgactctag ttcagcctta ttttccttga
    10441 tttgagcaac cagaacatct aaataaatag ccttacgttg tccttccaag tctaaaaact
    10501 tacgggcatt ctcagcttgc ttctcaagag gcttgatttg attatccaac tcgtagataa
    10561 tgtcctctaa gcggtccaga ttatcctgag tttgctgcag tttactctcg gtttcttttc
    10621 tgcgagtctt gtattttaaa actccagcag cttcttcaaa aatagctcgt cgttcctcag
    10681 gcttggaatt aaaaatctcc tcaaccttcc cttgggaaat aatagagaag gaatctcgtc
    10741 ccaatccagt atccaagaag aggtcatgaa tctcacgcag acggactttc ttgccgtcaa
    10801 tcttgtattc gctatctcca ctacgataga tatggcgttc caccctgatt tcttgacctg
    10861 catccttgat aaatccgtca tgattatcca gagtcacaac tacagaagca taattgagcg
    10921 gtttgcgact ttcggttcca gcaaagatga catccggcat cttgccccca cggagactct
    10981 tgacactaga ctcccccaaa gcccaacgca gactttctgt aatattggac tttccagatc
    11041 cattgggtcc aacaactgcc gtcacacctt ggtcaaaaac gaccttggtc ttatcagcaa
    11101 aagacttgaa cccctgaatt tcgatttcct ttaaatacat gaatccagcc ctttctcaac
    11161 ggcatttttg gcagcttcct gctctgctaa tttcttagaa cgaccttggc cttgaccgat
    11221 gctcttacct tcaacaagaa cttctacatc aaagacctta tcgtgagcag gccctgtttc
    11281 agaaatcacc tgataacgaa tagccacatc accattgacc tgaagcaact cttggagatg
    11341 ggttttatag tctgtaatca tctcaaattc gcctgcttct accttaggaa tcataacttg
    11401 gtagataaat tccttgacct ttgccacatc cttatccaaa agaagggcac caagaaaggc
    11461 ttcaaaggca tcaccaagaa tggtgtcacg attgcgacca ccagattttt cttccccttt
    11521 acccaacttg ataaactggt caaactggca atcacgcgca aaaccagcta aactctcctc
    11581 acggacaatc atagcacgga gttttgatag gtcaccttca ggctttttag gatatttttt
    11641 atatagatat tctgaaatca ataactgtag aacagcgtct cctaaaaatt ccaagcgttc
    11701 attgtgtgaa atttttaaga ggcggtgctc attggcataa ctcgtatgag taaaggcagt
    11761 ttccagtaac tttttgtctg caaattcgat ttcaaaatga ttctttagta cagtttgtaa
    11821 ttctttcata ccaacttctt tctaactgat aatagtcctt tttattatat caaaaaaagc
    11881 cccctgagtc actctaaaac gggactggaa agcatttggg aattctttag acagagattc
    11941 tcagttttag cggcaaattt gggtcaggat aaagaaaaaa gccctattaa aggcttttta
    12001 ggatgtttac atccaccctg agggaatcga acccccatct caagaaccgg aatcttacgt
    12061 gatatccatt acactaaggg tggaaacttg ttttattata acagaaattt gctctaataa
    12121 caagtttttt ggtcaaagac cccgtcttag tgggaagcat ccccattcca gatggagttt
    12181 ttcacgatca cataatcaac gtgtttaagg tcagcaacct gacgtccacc tgcataagaa
    12241 atagcacttt gaaggtcttg ttccatctca gttaaagtgt cttgcagatg acctttagca
    12301 ggaagcaaga tacgtttgcc ttccacattt ttgtaagcac ctttctgata ttgtgaggct
    12361 gaaccataat attctttgaa ctgttcacca tcgacttcaa tcgttttccc tggactttca
    12421 atgtgtcctg caaagaggga accaatcatg atcatgctag caccgaagcg gatagacttg
    12481 gcaatatcac cgtgagtacg aattcctcca tcagcgataa tcggtttacg cgcagccttg
    12541 gcacaccagc gtagagcagc caactgccaa ccacctgtac caaaaccagt cttaaccttg
    12601 gtgatacaaa ccttaccagg accgattccg accttagtag catctgcacc agcattttcc
    12661 aattcacgca cagcttctgg tgttcccaca tttccagcaa tgacaaaggt atctggcaat
    12721 tctttcttga tgtgttgaat catagaaatc acgctatccg catgaccatg agcaatatca
    12781 atagtgatat actcaggagc atcagccttg agctggctaa caaaatcata ctcataatcc
    12841 ttaacaccga cagatatgga agcaatgagc ccttgatcgt gcattcgttt aataaaagga
    12901 atgcgtcctg cctcatcaaa acggtgcata atgtagaagt aaccaccttt agccagttgc
    12961 tctgctacat tttcatccaa aatcgtctgc atattcgctg gcacaacagg tagtttaaag
    13021 gtgtgatttc ctaaagtgac acttgtatcc gcttctgcac ggcttttaat gacacattta
    13081 tttggaatca attgaatatc ttcgtaatca aaaattggaa attcatttaa catatcgatg
    13141 tctcgtttct tttgtaatga cctacctatg ctctcgcatc actacgcctt ttccgacgtt
    13201 tccttaattt a
//
LOCUS       DAVLTT010000051        13211 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLTT010000051 DAVLTT010000000
VERSION     DAVLTT010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13211
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.051"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(191..1393)
                     /gene="rpsA"
                     /locus_tag="VYN15_001624"
     CDS             complement(191..1393)
                     /gene="rpsA"
                     /locus_tag="VYN15_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV1452921.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1555..1626)
                     /locus_tag="VYN15_001625"
     tRNA            complement(1555..1626)
                     /locus_tag="VYN15_001625"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1592..1594),aa:Gln,seq:ttg)
     gene            complement(1636..1716)
                     /locus_tag="VYN15_001626"
     tRNA            complement(1636..1716)
                     /locus_tag="VYN15_001626"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1680..1682),aa:Tyr,seq:gta)
     gene            complement(1766..1996)
                     /locus_tag="VYN15_001627"
     CDS             complement(1766..1996)
                     /locus_tag="VYN15_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV1452922.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2164..2808)
                     /gene="pcp"
                     /locus_tag="VYN15_001628"
     CDS             complement(2164..2808)
                     /gene="pcp"
                     /locus_tag="VYN15_001628"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1452923.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2823..3746)
                     /locus_tag="VYN15_001629"
     CDS             complement(2823..3746)
                     /locus_tag="VYN15_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV1452924.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3743..4432)
                     /locus_tag="VYN15_001630"
     CDS             complement(3743..4432)
                     /locus_tag="VYN15_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV1452925.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4497..5189)
                     /locus_tag="VYN15_001631"
     CDS             complement(4497..5189)
                     /locus_tag="VYN15_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1452926.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAMKHLG
                     ITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMPTASS
                     GGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEKLESN
                     SKYQKELEKYIK"
     gene            complement(5245..6267)
                     /locus_tag="VYN15_001632"
     CDS             complement(5245..6267)
                     /locus_tag="VYN15_001632"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV1452927.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6397..8868)
                     /gene="parC"
                     /locus_tag="VYN15_001633"
     CDS             complement(6397..8868)
                     /gene="parC"
                     /locus_tag="VYN15_001633"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV1452928.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9288..11231)
                     /gene="parE"
                     /locus_tag="VYN15_001634"
     CDS             complement(9288..11231)
                     /gene="parE"
                     /locus_tag="VYN15_001634"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV1452929.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11367..12008
                     /gene="plsY"
                     /locus_tag="VYN15_001635"
     CDS             11367..12008
                     /gene="plsY"
                     /locus_tag="VYN15_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV1452930.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(12053..13211)
                     /locus_tag="VYN15_001636"
                     /pseudo
     CDS             complement(12053..13211)
                     /locus_tag="VYN15_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         3756 a         2967 c         2326 g         4162 t
ORIGIN      
        1 cgcaatgcct ttggttttcg gaactttgaa aacttcaaaa aacggatttt tatcgccctg
       61 aatatcaaaa aagaaagaac gaaatttgtc ctttctcgag cttagctttt cttcaaccca
      121 ctacagttga caaagagcca gaaaaatccc ttgtttagta aacaaaggat tttgtgaatt
      181 ttcaatttga ttaaagttcg atgtcaccaa acaaatcagc cattgaaaat cctgtttgtg
      241 tttctggaag ttcgaaatca cgcttttctt gacgtcttgg acgacgtgga cgagcagcac
      301 gtttttcttc tttttgtcct tcttcttggg ctggacgttc ttcaagagct ttaatagaaa
      361 gtgacacgcg ttctgcatct gcgttaactt caagaacttt aacttgaact tcttgaccaa
      421 ctttaagagc ttcttttgga ttttcaatcc gtttgtgtga aatttgtgat acgtgaacaa
      481 gtccatcgat acctggcaat acttcaacaa atgcaccgaa gtcagtcaaa cgtttaactg
      541 ttccttctac tacatcacct ttagccaatt tttgctcaac gccatcccat ggtcctggta
      601 ctgttgcttt aagtgaaagt gatacacgtc cttcttcttc gttaagatca aggattttca
      661 cttcaatttc ttcaccaaca gttacaactg attttggtga tacgttacgt tcatgtgaca
      721 attcagtcaa gtgaaccaat ccgtcaacac caccaaggtc gatgaaagcg ccgaagcttg
      781 tgatacgagc aactttacca gttacaacat caccaacagc caatttaccg aatacttcag
      841 cgcgagctgc tgcagtagct gcttcaacaa cttcacgacg tgaaaggatg aagcggtttt
      901 ctttagcgtt aacttctttg attttagtat caaattcttg acctacaaaa cgctcagcgt
      961 tacgtacgaa acgagtatcc aacattgaag ctgggataaa tccacgaaca ccttcaaatt
     1021 ctactgaaag tccaccttta acggcacgcg ttcctttaac agtaacaact tcttcttcgc
     1081 gaccaacaag tttgtcccat gctttgcgag cttcaaggcg ttttttagat acaaggtatg
     1141 taactgtatc agtatcttta ccaactactt gacgaagtac aagaacatcc aatacttctc
     1201 ctactttaac aaagtcattg atatctgcat cacgatcgtt tgtcaattcg cgaagagtca
     1261 agacaccttc aacaccagtt ccagagattg caacgttagc ttgagtcgca tcaactgtca
     1321 atacttcagc actaacaaca tcaccagtct caacttgact aacgctattt agcaaatctt
     1381 caaattcgtt catctaaaaa atcctccaac aatcaagttt ttcttaaact tgacatactt
     1441 ataatttttt tcctaagcac cagcaaggac atgttcatat cattcacgtc tttcaattat
     1501 aaaaataaaa taccctaaga tattttgctt tttatcttga ttattaccta agaactgggg
     1561 tagctggatt cgaaccaacg catgagggag tcaaagtccc ttgccttacc gcttggctat
     1621 accccattaa tgaaatggag agagagggat tcgaaccccc gaacccgaag gagcggattt
     1681 acagtccgcc gcgtttagcc tcttcgctat ctctcctaca atcaacatgg actattatat
     1741 catgaaaatt tcaaaaaaac aagacttatt ttgctaaatt ataattttca atcaaaattt
     1801 ccacagcttt ttccaatttt ttataaaaac tatcgacatt cccattcttt ataatggcaa
     1861 attgtccgtc taattcggca atttctccga taactttttt accgatagtc aatgtataac
     1921 cttcaaaact gtctttacca acattaactt tggcatccgc tacttgaatt tcgatttttt
     1981 tatctttctt gctcatttca tacctctctt cactttttct attttacaag aaaatcctaa
     2041 aactagcaag aaaaaactct atatcaggct tctctgatat agagttttat gtaaacaacc
     2101 tcaatcgatt tagcatagct aatagttagt aaacaagcat aattgactat cctttttagg
     2161 ttatcagtga gtctcaccgc ctactaactg caaatcctta tctttgtagt ctacaatagc
     2221 ttcaatagct acctctatgc ctcttacaat atcacataga ctcattcctg cagtattcgg
     2281 cttatttact acttgttcca tcatatatgg aatatgcatg aaacctgctc tcatattagg
     2341 gaatttttta tccactaaat aaagagcttg gtacatcaaa tgattgcaaa caaaggttcc
     2401 tgcactattg gatacaactg ccggaagtcc ctgttttttg atagcttgta ccatcgcttt
     2461 gataggtaaa ctactaaaat aggccgatgc tccatcaata cgaatcggtg tatcaattgg
     2521 ttgattgcct tcgttatcag gtatgcgagc atcatcttga ttaatagcca ctcgttcagg
     2581 tgttaagccg gtcctgccgc ctgcttgtcc aatacaaagt acagcatctg gttgatatcg
     2641 taatatttct gcctctaaaa cttctgacga cttataaaaa accgttggaa tttctaccca
     2701 gcgaacttca gccccattaa tctcagatgg taataatttt acagcctcca aagctggatt
     2761 aatcttttca cctccaaaag gattaaaacc tgtaaccaat attttcattt tattttcctt
     2821 tactaaaatg cgagaaagta cattaagaat atgtgaataa caatcattac tagagcaaca
     2881 cctgcttgag cctttataac gccattctga tctttcatat ccatcaatgc tgctggtaga
     2941 gcgttaaaat tagcagccat tggggtcaat aaggtcccac aataacctgc tgtcatggca
     3001 agagcaccag ccacaattgg attagctccc agagcaaata caaagggaac tccaacacct
     3061 gctgtaataa cggtgaatgc tgcaaaagca tttcccataa tcattgtgaa tagaaccatt
     3121 ccaagaacat aggccaaaac tcctataaag cgactatctg aaggaacaat accgctgatc
     3181 agatgagaga taacatcacc aacacctgct acagtaaaaa tagcccccaa agcccctaat
     3241 aattgaggaa caatcccact tgttgaaact tgctgagtca ttcgattatt ttctgataac
     3301 agactcttag ggtgactatt ggtaatcaca agaacagaaa ttgtagcaaa caaggcggca
     3361 aggctaatcg aaatcttgct aaattctgga atcatttgcg ctaagaccaa cgcaagtatt
     3421 gccatcagca taactggaat aaaaatttta tttttcaacc tgttagattc aatattggct
     3481 ttcatttcat ctaaggatgg caaggttccg atacggactt gcttaaacaa tgttaacagc
     3541 gataatagga ttacaataat accaatactc atatttggca tataggaacc acctataaac
     3601 gtaatagaca atagagtcca aaatgcagat gtcccaagtc gaactgggtt tgttttatct
     3661 ttataactac aataggctgt atggagaaat tgacaaccaa tcacaatata ggtcaactct
     3721 aatagttgct ttgccaactc tgtcattttt gttctcctcc cctagtcttt tttgatatca
     3781 attttttatc aaataaataa ttgtaaatcc ccactacaat aagtgttata acagcaacaa
     3841 taatagatgt agaagcaatc cctgcataat tgctttcata gcctaactga tctaatgttc
     3901 cccctatcaa gaggactccc ccagcaccta caaacgtatt ttgagcaaag aaatttccaa
     3961 aattttcatt cgctgccgca cgcgctttta ttgtctcatc ttcaacctct gttaactttc
     4021 tacctaattg agactctgca gctgcttctc ccataggttg aaccaaaggt ctgacaaact
     4081 gagggtgtcc tcctagacga attgaaaaga aaccagctaa ctctcgaata aagaaataaa
     4141 ctgtatagaa gtttccaact gtcagacctt taatctttcg aatcaaatcg attgatcgtt
     4201 gcttgagtcc aaaggtttct gacagcccca caagaggcaa ggtaaccata aaaatcgtga
     4261 gcactcgctg attgctaaat tcttttccca aaatctccaa aaattcaacg agagaaacac
     4321 ctgaaactaa agctgtaacc aaaccagcta agactactgt tgcaattgta tcaaatttta
     4381 aaataaaacc cacaacaatg attgctattc ctattaatct aatccactcc atatcaaact
     4441 cctttatatt caaaatgaca gtattttaaa aattttatca agatcaatac cattccttat
     4501 ttaatgtatt tttctagttc tttttggtat ttgctattgg attccaattt ttctttttgc
     4561 cattttttaa aaacctcgtt atattctttt gttgtaacaa tatctttttg caatttcatt
     4621 cctttaaaga tatatggttc ccccttaata ccaacttgtg agtatggttt tgagaatggt
     4681 actacgttac ttacaactgg agaaccacca gatgaagctg ttggcatcaa taatgaacta
     4741 tctgtcgacc aagcttgagc tttggcatat ttttcatatc tcttctctag gtcagtggtc
     4801 tcagaaacag catcttctaa caatttctta tatttatcca aaccaggttt agctacaaca
     4861 tccttatctt ttcctttcgt aatgccaagg tgtttcatgg cagaaccaga ttttggatcc
     4921 ataatattca agtaagacgc tggatcttga tagcttggag cccatcctgt actgttcaaa
     4981 tcatagtctt tttgagaagg agcaacattg ccgtatttat cattttccat caaaccatca
     5041 ataacgtctg tcctcgatgt tcgagtcgct atactgtagc ccaatgatgc tggatctact
     5101 gcatagacat aagaaaatgt tgtcggtgca tctgcttctt tatcagtttt tccacaagcc
     5161 actaaaatag ctgacgtgct caggaccact cctgctgtta agagccactt tttctatttc
     5221 ataaaaaatc tcctttggtt tattttaatc tacttttaca atccaacctt ctggcgcttc
     5281 aatatcgcca aactgaatac ccgtcaattc attatataat ttacgcgtca caggacctac
     5341 ttctgtttca ctatagaata catggaaatc atcaccatgt tgaatacctc caattggaga
     5401 aataaccgct gctgtaccac aggcacctgc ctctacaaaa cggtcaagat tatcaattgg
     5461 aacatcaccc tcaataggag ttaatcccaa gcgatgttct gccaaataaa gcaaggaata
     5521 cttggtaata gatggcaaga tagatggact caatggtgtt acaaattcat tatcagctgt
     5581 aattccaaag aaattagctg atccgacttc ttcaatcttt gtatgagttg atgggtccag
     5641 atagataaca tctgagaaat ggcgtgactt ggccattttt cctggtaaga gacttgcagc
     5701 atagtttcca ccaaccttag ccgcacctgt accatttggt gctgcacggt cgtactcatc
     5761 ctgaatcaag aagttggttg ggaccaaacc acctttaaag taatttccaa ctggcatagc
     5821 aaagatggtg aaaatgtact cttctgccgg ttttaccccg ataatatctc cgacaccaat
     5881 caaaagaggg cgaagatata aggttccacc tattccgtat ggtggtacgt attcttcatt
     5941 cgcacggaca actgctttac aagcttctac aaacatgtct gtcggaactt gtggcatcaa
     6001 gagacggtca catgtacgtt gcaggcgttt agcattttca tcaggacgga acagttgaac
     6061 actgccatcc ttagtacgat aagctttcaa accttcaaat gcttgttgtc catagtgaag
     6121 acttggagaa gactctgaaa tatgcaaagt tgcatcctct gtaagctctc cttgatccca
     6181 ttgtccattt ttgaaatgag caagatagcg ataaggtaat ttcatatagg aaaaaccgag
     6241 gttttcccaa tcaatcgtta ctgtcatatt ccactcctta ttctaaaaac ctatttctta
     6301 tattctacac tatttttcta aaatagcaag tatattttgt aattttcaga aaattcctcc
     6361 aataaaaacc atcttagaac tgattcttca tttcacttat ttatcttcag taactacttc
     6421 ctgaagataa gcgtcaaaaa cttcttcatc tgaaatcgtg tcagaaatga agcttccatt
     6481 gctagtgcgt tctgacaagt tcaagtcttg caatcggctt tcatagattg ttcctttatt
     6541 ggattggaca agcagagttt ggtcgttcac atccacttcc gtactgaaga aatcgccaac
     6601 aaatccttgc tctgcaactg ctcctgccaa gaagacacga tgcggtttgt ttttcaactc
     6661 acgcaagact tgtaatcctc gtttggcacg gctggttgct agaatttcct caatggaaac
     6721 acgtttcaag cttccacgct gggtcaagag gtagaaggac gaagtattac agataaagcc
     6781 agattggagg acatcatctt ctttcaaatt catagccttg acacctgctg ccttagcacc
     6841 gacaaccgga acctcttcga tattgaaacg cagggcataa ccattttgac taaccaagac
     6901 aacatcatct agtttaatcg gagccactgc tacaatctga tctgtatcgt ctttgagctt
     6961 agcatacttg acagacttag atctataggt ccgccatgga gtgaattctt ttcgctctac
     7021 ccgtttgatt tgaccaaggc gagtcgctgc aaagtaggtt gtcgcatcgt caaactgatc
     7081 cagtacttcc acataaagga tttcttcatt cgtttcaaag tttgtgatgg tttggctcag
     7141 atgctctccg atgtccttcc aacgaatatc tgccaactca tggattggtc tgtagatgac
     7201 atttccaaga cttgtgaaca tcaagaggtg ctgggttgtc ttggcagatt gaacaaaaat
     7261 caaacggtca tcatcacgct tgccaatttc ttccaaggtg gaagccgcaa aggaacgtgg
     7321 actggtacgc ttgatgtaac ctgccttggt cacgctgacg taggtatctt cctcagcgat
     7381 aagactagct gtatcaatct caattgcttt cgcagtgtct tctaaagaac tcaaacgagg
     7441 agttgcaaat ttcttcttga cctcacgaag ttctttcttc atgagattgt acatagtcct
     7501 ttcatcacca ataatagccg ccagcatagc aatcttctca cgaagctctg cttcttcttc
     7561 ctgcaagaca accacatcgg tattggtcaa acggtacagt tgcaaagtta cgatagcctc
     7621 agcctgttct tccgtaaaat catagctaac tttgaggttt tccttggcgt ccgccttatt
     7681 ctcagaagca cggataagag caatgacttc atccaaaatc gaaatcacac gaatcaaacc
     7741 ttcgacgata tggagacgtt tctcagcctt ttctttgtca aagcgtgaac gcgccaaaat
     7801 cacttctcga cggtgagcga tgtagctaga caggattgga acaatcccaa cctgacgagg
     7861 tgtgaaattg tcaatcgcca ccatattaaa gttgtagttg atttgtaggt cggtgtactt
     7921 aaataagtag ttgagaacaa gctcagtatt agcgtctttc ttaagttcga tagcgatacg
     7981 aagaccatca cggtcagact catcacgaac ctcagcaatc ccagctacct tgttattaac
     8041 acgaacatca tcgattttct tgactagatt ggccttattg atttcataag gaatctcagt
     8101 aataacgatt tgttccttac caccttttag cttttcaatt tcagtcttgg aacgaacaac
     8161 cacgcgccct ttcccagtct cataagcttt cttgatttca tcacgaccct gaataatagc
     8221 ccctgtaggg aagtctggtc caggcaagaa ttccatgagt ttatcaatct ttgcagttgg
     8281 gtggtcaatc atgtaaactg cagcatctat gacctcagct aaattatggg gaggaatgtc
     8341 tgtggcataa ccagccgaaa tcccagtcga accattgacc aagaggtttg gaaaggctgc
     8401 tggcaagacc gttggttctt tctccgtatc gtcaaagttc catgcaaaag gaactgtctt
     8461 tttctcgata tcctgaagaa ggtagcctgc aatttcagac aaacgtgcct cagtataacg
     8521 catagccgca ggaggatctc catccataga accgttatta ccgtgcattt caactagaat
     8581 ctcacgattt ttccagttct gtgacatacg aaccatggca tcatagatag aagaatcccc
     8641 gtgtgggtgg aaattcccca tgatgttccc gactgacttg gccgacttac ggtagctctt
     8701 gtcaaaagta ttgctatcct tattcataga ataaagaata cggcgctgaa ccggcttcaa
     8761 cccatcacga atatctggca aagcccggtc ttgaataatg tacttggagt agcgaccaaa
     8821 gcgctctccc atgatgtcct ccagggacat gttttgaatg ttagacataa gatacaaagc
     8881 ccataaaata ccaagtgaaa atagaaaatt cttgaagtaa gcaaactcac aagagaattt
     8941 atctttttca cacaatatct agggcgtgtt caactccttt caaagaatgt agagtaggtt
     9001 tttatgcagt aaaagatatt ttacgggaat tcgtcccgtg ttcagttacg ataagtaacc
     9061 aaactatcct gtttgtattt ttcaatatga aaatctggtt ttccaaaatt agtcttagtt
     9121 tgtgtcttaa ccgctccctt aagcgcctct ttaagataag cactcatagc agattcttca
     9181 ttaataatcc tgcaattttt tcaaaccaag attttcaatc tgctttttca catagtcatt
     9241 cacatccgac tctaatttcc agtttactaa catattattt tctttcatta aaacactgtc
     9301 gcttcttcta gcgtaaactt gacattatct tcaatccatt tacggcgtgg ttctacctta
     9361 tctcccatga gaacattgac gcggcgttcg gcgcgcgcta aatcttcaat tgtgacacgg
     9421 atgagggtac gtgtttctgg gttcatggtt gtttcccaga gctggtccgc attcatctca
     9481 ccaagtcctt tgtatcgttg gagggtagcg cctttaccga actgtttacg gagttcttct
     9541 agttctccgt ccgtccaagc gtaggccact tcttctttct tgcctttacc tttggacatc
     9601 ttgtaaagag gtgggagggc aatatagaca tgacctgcct cgactagcgg acgcatgtaa
     9661 cggtagaaaa atgtcaagag caaggtctgg atatgggcac cgtcggtatc cgcatcggtc
     9721 atgataatga tcttatcata gttggcatct tcaatagaga agtctgctcc aacacccgca
     9781 ccaatggtat aaatcatggt attgatctct tcatttttga ggatatccgc catcttggcc
     9841 ttggctgtat tgataacctt accacgaaga ggtagaatag cctggaactt gcggtcacga
     9901 ccttgtttgg cagaaccacc ggcagagtcc ccctcaacta gatagagttc attcttagca
     9961 ggattcttag attgggctgg ggtcaatttc ccagacaaca agcccttatc tttcttgttt
    10021 ttcttcccat ttcggctctc atcacgcgcc ttacgtgctg cttcacgagc atcacgggcc
    10081 ttgatagcct tgcggatgag gttagaagct aattccccat tttccataag gaaaaaggtc
    10141 aacttatcag ccactattcc atccacaact gggcgagcta gggggcttcc tagtttatcc
    10201 ttggtctgtc cttcaaactg caagtgttct tcaggaacta agatagaaag aacggccgct
    10261 agtccctcac gatagtctga accttcaagg tttttatctt tttccttgag aagacctgtt
    10321 ttacgtgcat agtcattcat gaccttggta atggcagact tgagtcctgt ctcgtgcgtt
    10381 ccaccgtcct tggtgcgaac gttattgaca aaggatagaa tgttatctga gaatccgtca
    10441 ttgtactgga gggctacttc cacttgaaaa ccattgtctt ccccttcaaa gtaaagaact
    10501 ggcgtcaaga tttccttatc ttcgttgaga taagaaacaa aatcttgtac tccattctca
    10561 tagtggaact caatcgcttc atctgttcgc ttgtccgtta aagacaaggt cacatttttc
    10621 aagagaaagg ctgattcatt aaggcgctct gaaatggtat tgtacttgaa atctgtcgta
    10681 gaaaagatag tcgcgtcagg cataaaagta actttggtgc ctgttttaga cttgggtgct
    10741 gtaccgattt tcttcaaagt cgtgacaggt tttccaccat tttcgaaacg ttgcttgtaa
    10801 actgcgccat cacgggtaat ttcaacttct aaccagctag aaagggcgtt aacaacggaa
    10861 gaacccactc cgtgaagtcc acctgatgtc ttatagccac cttgaccgaa tttccctccg
    10921 gcatgaagaa tggtaaagat aacctcaaca gttggaattc ccatagcgtg catacctgtc
    10981 ggcatcccac gtccatggtc ttgaaccgtt agactaccgt ctttattgat agttacatcg
    11041 atacgatcac caaacccaga caaggcttca tcgactgcat tatcaacgat ttcccaaact
    11101 aggtgatgaa gaccagcgcc atcggtcgat ccaatataca tccccggacg ttttcggacc
    11161 gcatccaacc cttctagcac ctgaatagca tcatcattat aattgttaat attgatttcc
    11221 ttttttgaca caaggaacct cctattcgtt catctttact attctacagg ttttccaagg
    11281 attttgcaaa atttttcttt ctccgatgtg acaatttcag cagagattct ctgcttttct
    11341 ttcccaattc atgatataat aggagtatga ttacaatagt tttattaatc ctagcctatc
    11401 tgctgggttc gattccatct ggtctctgga ttggacaagt attctttcaa atcaatctac
    11461 gcgagcatgg ttctggtaac actggaacga ccaatacctt ccgcatttta ggtaagaaag
    11521 ctggtatggc aacctttgtg attgactttt tcaaaggaac cctagcaacg ctgcttccga
    11581 ttatttttca tctacaaggc gtttctcctc tcatctttgg acttttggct gttatcggcc
    11641 ataccttccc tatctttgca ggatttaaag gtggtaaggc tgtcgcaacc agtgctggag
    11701 taattttcgg atttgcgcct atcttctgtc tctaccttgc gattatcttc tttggagctc
    11761 tctatcttgg cagtatgatt tcactgtcta gtgtcacagc atcgatcgcg gctgttatcg
    11821 gggttctgct ctttccactt tttggtttta tcctgagtaa ctatgactct ctcttcatcg
    11881 ctattatctt agcacttgct agtttgatta tcattcgtca taaggacaat atagctcgta
    11941 tcaaaaataa aactgaaaat ttggtccctt ggggattgaa cctaacccat caagatccta
    12001 aaaaataaaa tgccagttct gtgaactgca ccccaaaagt tagacaatta atttatccga
    12061 aggatttagt tctgtattgc acagggctaa gtccttttag ttttacctta attcgtttat
    12121 tgttgtagta atcaatatag tctacaatag cttgttccaa ttgattaagt gatttaaatg
    12181 ttttctcata gccataaaac atttccgatt tcagaatccc aaagaagaac tccatcatac
    12241 cgttgtcttg gctgtttccc ttgcgtgaca tggatgcttg aattccctta ccctcaagaa
    12301 actgatgata agaatcgtgt tgatattgcc agccttggtc actatggaga atcgtattct
    12361 cgtagtgctt ctctgtgaag gcttgttcca acattgtttg tacttgttct aagttgggtg
    12421 aaattgaaag attataggcg ataatttcac tgttaaagcc atctaaaact ggtgataagt
    12481 aaagcttttg agtacttgct ggaatggcaa attctgtcac atctgtgtag cacttttcca
    12541 ttgttttaga gccttcaaat tggccttgaa tgagattctc tgctttctta ccaacgtctc
    12601 ctttatgaga agaatatttt cgtttctgtc gcattttagc ttgtaaattg agtactttca
    12661 tcaagccttg aactctttta tgatttacca gataaccacg atttcttagt tctaaataaa
    12721 ttcgacgata accataattt cccttgtgtt cgataaagat ggattgaatt tcagctttaa
    12781 gctcttggtc cttatctggt ttatctagct gtttcaagtg atagtagtag gtccaacgag
    12841 ctagtttaat ggcttttaga agaagagcta acgaaaactc agtcattaat tcttgaacaa
    12901 tttctgtctt tcttctttct ctttttcctc cttcaatcgg agttctctta acttttttag
    12961 gatggcattc tccgctctca ggtactcatt ttctgcttga agacgttcta attctgtcct
    13021 ctcttcaggt ctcgttcttg gcttacgtcc cattttaggt actctccctc ttggtttctc
    13081 aacaatagta tacccgtttt tcctgtattg tgctagccag ttaagaagta tcgtacgact
    13141 tgggagaccg tattcaagag aaactctatc tttagtctag ccttcatgtc agactttatg
    13201 aatcatttct t
//
LOCUS       DAVLTT010000052        12657 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLTT010000052 DAVLTT010000000
VERSION     DAVLTT010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12657
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.052"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            463..1506
                     /locus_tag="VYN15_001637"
     CDS             463..1506
                     /locus_tag="VYN15_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV1452931.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            1673..3760
                     /gene="topA"
                     /locus_tag="VYN15_001638"
     CDS             1673..3760
                     /gene="topA"
                     /locus_tag="VYN15_001638"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV1452932.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GGIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3866..4225
                     /locus_tag="VYN15_001639"
     CDS             3866..4225
                     /locus_tag="VYN15_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV1452933.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4318..4950
                     /locus_tag="VYN15_001640"
     CDS             4318..4950
                     /locus_tag="VYN15_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV1452934.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            4994..5650
                     /locus_tag="VYN15_001641"
     CDS             4994..5650
                     /locus_tag="VYN15_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV1452935.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5669..6763
                     /locus_tag="VYN15_001642"
     CDS             5669..6763
                     /locus_tag="VYN15_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV1452936.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6775..7812
                     /gene="leuB"
                     /locus_tag="VYN15_001643"
                     /pseudo
     CDS             6775..7812
                     /gene="leuB"
                     /locus_tag="VYN15_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            7809..8078
                     /locus_tag="VYN15_001644"
     CDS             7809..8078
                     /locus_tag="VYN15_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV1452937.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            8082..8441
                     /gene="leuD"
                     /locus_tag="VYN15_001645"
     CDS             8082..8441
                     /gene="leuD"
                     /locus_tag="VYN15_001645"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV1452938.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8603..9225
                     /locus_tag="VYN15_001646"
                     /pseudo
     CDS             8603..9225
                     /locus_tag="VYN15_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            9391..11322
                     /locus_tag="VYN15_001647"
     CDS             9391..11322
                     /locus_tag="VYN15_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV1452939.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENSIFDMKRSTNEFIGRSAMVTK
                     LLCIYSEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNESDENDDADY"
     gene            11309..12625
                     /locus_tag="VYN15_001648"
     CDS             11309..12625
                     /locus_tag="VYN15_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV1452940.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKKQKILETINQEIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEIGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEENFKAIIDEEVGRK"
BASE COUNT         4043 a         2122 c         2712 g         3780 t
ORIGIN      
        1 acactataat ttagtgtaat tgagaaagga gaaatgattg tgattgatgt tggctaggtt
       61 atgttcaatg attcctaccg tctcaaatct tgtcagtaag gaaaaataaa ttcttcaaaa
      121 gtagagatta caaggcttgt ttaagaaaga attcaaagac cttgacaaat aaaaataaaa
      181 tggttattat aagaaatggt ctaaaataga tgatgatact tttcgaaaat ctttttacgt
      241 cagctcagct ttgccttgct gtgttttgag caagctacgg ttagcttccg agtttgattt
      301 tcatttacta gaaatgaaac tgatgagaga tatcagtaga catttgagtc aggatattat
      361 ggaaaatgat aaaaagagct cgtgagattg gcatatcaga ctactaaagt attgagtttg
      421 ttaggatttt agcgactagt tagctgggaa aggaagatat ttgtgacaaa taataaactg
      481 tattcgttga tagaatttag aaataaaata tatgaagaat tagaactttc cagaagtgat
      541 ttagcgattt tactatgtgc catgcttatc gcctctatcg gattaaatat ggattcgact
      601 cccgtgatta ttggagccat gttaatctct cctttgatga cacctattct gggagtgggg
      661 ctctctctag ctatatttga ttttaaattg ttaagaaaat cttttaaaat attagctatt
      721 caaattcttg ccagtctaat agcttcaaca ctttattttt atctttctcc catttcgtat
      781 gctagttcgg agattgttgc tagaacctct ccgactattt gggatgttct cattgctttt
      841 gtaggaggga tagcaggtat tattggtgct aggaaaaaag agaccaataa tattgttcct
      901 ggtgttgcta ttgcaaccgc cttgatgcct cctctttgta cagtaggtta tgctattgct
      961 tctgctaatc taaaatttat cataggctcc tcttacctat tcctcatcaa ttgtagcttt
     1021 attgtcattg cgacttatat aggtgttagg ttgatgatgg ttaagaaaca ttattttaaa
     1081 gataatgaag aagactctaa aatgcgtagg attttgcttc tagttgctgt tttgctgatg
     1141 attccgagtt tcatctctgc aacgacttta gtgagagaaa cgttgaaaaa agagtccctt
     1201 aagaaattta tatcagagca gtttcagggg tataatattt tgaaaaaaac ctattctaaa
     1261 aagactcata ccctaaagct aaccatttca ggaaattatt tgacagaaga agaactcgat
     1321 atgatttcaa gtaagagagg tgactatggt ttaagtgatg tttctgttca agtttcacaa
     1381 ttgtctgatt cagaacaact tagtaaggaa gaactggtgg agtatttctt ccagtatatc
     1441 aaggataagg aagcaaaaga aaaggaaaaa gccaataaat ttgatacaga gtctgaggag
     1501 caataatttc ttgagaatag ctggtttctc tcgtgagtct tctatgtata tcaaaggaag
     1561 actgaggttt taagtataaa acttttcttc tattatagta gctaagtctt gacagggttc
     1621 aaaaaatggt ttacacttta taaagtttat tactttgaaa aggtgtgata ctgtggctac
     1681 ggcaacaaaa aagaaaaaat caacagttaa aaaaaatcta gtcatcgtgg agtcgcctgc
     1741 taaggccaag acgattgaaa aatatctagg cagaaactac aaggttttag ccagtgtcgg
     1801 gcatatccgt gatttgaaga aatccagtat gtccgtcgat attgaaaata attatgaacc
     1861 gcaatatatc aatatccgag gaaaaggccc tcttatcaat gacttgaaaa aagaagctaa
     1921 aaaagctaat aaagtttttc tcgcgagtga cccggaccgt gaaggagaag cgatttcttg
     1981 gcatttggcc catattctca acttggatga aaatgatgcc aaccgtgtgg tcttcaatga
     2041 aatcaccaag gatgcagtca aaaatgcttt taaagaacct cgtaagatcg atatggactt
     2101 ggtcgatgcc caacaagctc gtcggatctt ggatcgcttg gtagggtatt cgatttcgcc
     2161 tattttgtgg aagaaggtca agaagggctt gtcagcaggt cgcgttcagt ccattgccct
     2221 taaactcatc attgaccgtg aaaatgaaat caatgccttc cagccagaag aatactggac
     2281 agttgatgct gtctttaaaa agggaaccaa acaatttcat gcttccttct atggagtaga
     2341 tggtaaaaag atgaaactga ccagcaatga cgaagtcaag gaagtcttgt ctcgtctgac
     2401 tagtaaagac ttttcagtag atcaggtgga taagaaagag cgcaagcgca atgctccttt
     2461 accctatacc acttcatcta tgcagatgga tgctgccaat aaaatcaatt tccgtactcg
     2521 aaaaaccatg atggttgccc aacagctcta tgaaggaatt aatatcggtt ctggtgttca
     2581 aggtttgatt acctatatgc gtaccgattc gactcgtatc agtcctgtag cgcaaaatga
     2641 ggcggcaagc ttcattacgg atcgttttgg tagtaagtat tctaagcacg gtagcaaggt
     2701 caaaaacgca tcaggtgctc aggatgccca tgaggctatt cgtccgtcaa gtgtctttaa
     2761 tacaccagaa agcatcgcta agtatctgga caaggatcag ctcaagctat atacccttat
     2821 ctggaatcgt tttgtggcta gccagatgac agcggccgtt tttgatacca tggctgttaa
     2881 attgtctcaa aaaggggttc aatttgctgc caatggtagt caggttaagt ttgatggtta
     2941 tcttgccatt tataatgatt ctgacaagaa taagatgtta ccggacatgg ttgttggaga
     3001 tgtggtcaaa caggtcaata gcaaaccaga gcaacatttc acccaaccgc ctgcccgtta
     3061 ttctgaagca acactgatta aaaccttaga ggaaaatggg gttggacgtc catcaaccta
     3121 cgcgccaacc attgaaacca ttcagaaacg ttattatgtt cgcctggcag ccaaacgttt
     3181 tgaaccgaca gagttgggag gaattgtcaa taagctcatc gttgaatatt tcccagatat
     3241 cgtaaacgtg accttcacag ctgaaatgga aggtaaactg gatgatgtcg aagttggaaa
     3301 agagcagtgg cgacgggtca ttgatgcctt ttacaaacca ttctctaaag aagttgccaa
     3361 ggctgaagaa gaaatggaaa aaatccagat taaggatgaa ccagctggat ttgactgtga
     3421 agtgtgtggt agtccaatgg tcattaaact tggtcgtttt ggtaaattct acgcttgtag
     3481 caatttccca gattgccgtc atacccaagc aatcgtgaaa gagattggtg ttgagtgtcc
     3541 aagctgtcat cagggacaaa ttattgagcg aaaaaccaag cgtaatcgcc tattctatgg
     3601 ttgcaatcgc tatccagaat gtgaatttac ctcttgggac aagcctgttg gtcgtgactg
     3661 tccaaaatgt ggcaacttcc tcatggagaa aaaagtccgt ggtggtggca agcaggttgt
     3721 ttgtagcaaa ggcgactacg aggaagaaaa gattaaataa gaggaggggc ccgaaagtaa
     3781 atttcaggct ccttttggtt agaacttgac aaaatacatc attttatgcg aaactagaag
     3841 aagattattt taactaggag aagttatgcg tcttatctat ctgataattg gttttttatc
     3901 actggccttg gctattgttg gggttgtttt acccttgttg ccgacaacgc ctttcctttt
     3961 gttgtctatt gcttgtttct ccagaagttc caagcgtttc gaagactggc tttatcatac
     4021 caagctctat caaacatatg tagctgattt tcgcgagacc aagtctatta cgcgtgaacg
     4081 aaagaaaaaa atcatcgtct ctatctacgt cttgatggga atttctattt attttgcacc
     4141 tcttttacca gtcaaaatcg gtctgggtgc tttgaccatc tttatcactt attatctctt
     4201 caaggtcatt ccagacaaag aatagttaaa acagtagtta tttgccttga taaaattgaa
     4261 agcatattca taacaatatg atataataaa tttgaagtaa tattcaagga gaatcaaatg
     4321 atttacgaat tttgtgctga aaatgtgact ttacttgaaa aggcgatgca ggctggagct
     4381 cgtcggattg aactctgtga taatctagca gttggtggga caacacccag ctatggagtg
     4441 actaaggcag cggttgaact ggcagctaac tacgatacaa ccatcatgac catgattcgg
     4501 ccacgtggtg gtgactttgt ctataatgac ctagaaattg ctatcatgct agaagacatt
     4561 cgtttgactg ctcaggctgg aagtcaaggg gttgtatttg gagctttaac tgctgataaa
     4621 aagttggata agcctaatct ggaaaagtta attgctgcat caaaaggaat ggaaattgtc
     4681 tttcacatgg cctttgatga actaagtgat gaagatcaac cggaagctat tgactggctc
     4741 agtcaagccg gtgtcactcg tatcctaact cgtgctggtg tgtctggcga ctccttagaa
     4801 aaacgttttg ttcactatca cagaattttg gagtacgcta aaggtaaaat tgaaattcta
     4861 ccaggtgggg ggattgacct tgacaaccgt caaaccttta ttgaccaggt gggggtaaca
     4921 caattgcatg gtactaaggt tgttttttaa aaaatagaaa ggaactgcta gctttgggta
     4981 gcagttttca cttatgtttg aaatttttaa atcctatcaa tttaatcaag aaaaggctca
     5041 tgattatggt tttatagaaa atagcgaagt ctggacatat agttgccaga ttttgcaagg
     5101 tgactttgtc atgactgtgt ccatcactgc tgataatgtg aactttcaag tctttgacca
     5161 agagactggt gacctctatc ctcacgttta tatggaaagc atgaggggaa gttttgtcgg
     5221 aaatgtccgt gaggcttgtc tggagattct ttaccagatt cggaaggctt gttttgatgt
     5281 gcaagatttt atctgtcatc agactaagcg tatcatgact caagttcagg aaaagtatgg
     5341 aaaccagttg gagtatctgt gggaaaaatc gcctgataca gctgtattgc gccatgaagg
     5401 caatcaaaag tggtatgccg tcttgatgaa aatctcttgg aataagctgg aaaagggcag
     5461 agaaggacaa gtggaagcag tcaacctcaa gcatgaccaa gtagctaatt tgctttcaca
     5521 aaaggggatt tatccagcct tccatatgag caagcgctac tggattagtg tgtcccttga
     5581 tgatacttta tcagatgaag aagtactgga attgatagaa aaaagttgga acttaacctc
     5641 taaaaaatga aatattttaa taattttcat gaactttcaa ttagctaaat attctttact
     5701 gaagagattt ttagaaaata taggatttac cacactagag gaatatggtg ccatcttcaa
     5761 atatctgatt gagaatgtca agacggatcg tcagatcatc tattcgcctc actgtcatga
     5821 tgacctcgga atggcagtgg caaatagcct tgctgctgtc aagaatggtg caggacgtgt
     5881 tgaagggact atcaatggta ttagggagcg agctgaaaat gctgctttgg aagaaattgc
     5941 agtggctctc aatattcgcc aagattacta ccaagtagaa accagtattg tcctaaatga
     6001 gaccatcaat acgtcagaaa tggtttctcg cttctctggt attccagttc ctaaaaacaa
     6061 agccgtcgtt ggtggcaata ccttctccca cgaatctggt attcaccaag atggagtcct
     6121 taaaaatcct ctcacttatg agatcatcac acctgaattg gttggtgtta agattctgct
     6181 tggaaaatta tctggtcgcc atgcttttgt tgagaaactg agagaattgg ccctagattt
     6241 tacagaagag gatatcaaac cactctttgc taagttcaag gcactggtcg ataagaagca
     6301 agaaatcaca gatgcagata ttcgagcttt ggtagctgga accatggttg aaaatccaga
     6361 aggcttccac tttgatgatt tacaacttca aactcatgca gataatgaca ttgaagcgct
     6421 cgttagccta gccaatatgg atggtgagaa agtcgaattt aatgcgacag ggcaaggttc
     6481 cgttgaagca atctttaatg ctatcgataa gttctttaac caatctgttc gtttggtgtc
     6541 ctacactatc gatgcggtaa cagatggaat cgatacccag gatcgggttt tggtcactgt
     6601 tgaaaacaga gatacagaaa ccatctttaa tgcagcaggg cttgattttg atgtgttgaa
     6661 ggcttctgct attgtctata taaacgctaa tacctttgtt caaaaagaga atgcaggtga
     6721 gatgggacgc agtgtttctt accacgatat gcctagtgtg taaaggagaa ggctatggca
     6781 aagaaaatag tagctctagc aggagacgga attggcccag aaatcatgga ggttggttta
     6841 gaagttctgg aggctctagc tgaaaaaaca ggttttgact atgagattga cagacgaccg
     6901 ttcggaggtg cagatattga tgcagcatga cctcccttac ctgatgaaac ccttaaggca
     6961 agtagggaag cagatgctat cctactagta gctatcggta gtcctcagta tgatggagca
     7021 gtggttcgcc ctgaacaagg cctgatggct ctccgtaagg aactcaatct ttacgctaat
     7081 attcgtcctg taaaaatctt tgacagtctc aagcatttgt cactactcaa actggaacga
     7141 attgctggtg tagactttgt cgtggtgcgt gaattgacag gcgggattta ctttggagat
     7201 catattcttg aagagcgcaa tgcgcgtgat atcaacgact atagctatga ggaagtggag
     7261 cggattattc gcaaagcctt tgaaattgca agaaatcgca gaaaaatcgt tactagtatc
     7321 gataagcaaa atgttctagc gacctcaaaa ctctggcgga aagtagctga ggaagtcgca
     7381 caggatttcc cagatgtaac cttggaacat cagctggtag actcagctgc tatgcttatg
     7441 attaccaatc ctgctaagtt tgatgttatt gtaacggaga atctttttgg agatatttta
     7501 tctgatgaat caagcgtctt atctggtaca cttggggtta tgccatcagc cagtcattct
     7561 gaaaatggac caagtctcta tgaacctatt cacggttcag cacctgatat tgcaggtcaa
     7621 ggaattgcca atcctatttc catgatttta tcagtttcca tgatgttgag agatagtttc
     7681 ggacgttatg aggatgcaga gcgtatcaaa cgtgctgttg agacaagtct ggcggcagga
     7741 attttaacga gagatatagg aggtcaggct tcaacaaagg aaatgacgga agctattatt
     7801 gcaaggttat gaagttagac gaaaaaatta ctctagtcct tttgatttgg aatgtcatca
     7861 ttttcttgat ttatggtatt gacaaatcta aggcaaggag aagagtttgg cgcatccctg
     7921 agaaaatctt acttatttta gcctttactt ttggtggttt tggtgcctgg ctagcaggaa
     7981 tcatctttca ccacaagact cgaaaatggt actttaaaat agtttggttt cttgggatgg
     8041 tgaccacact agtagcctta tattttattt ggaggtaatg gatggcaggg tcttcgaggg
     8101 aatacgctgc ttgggctcta gcggactatg gttttaaggt cgtgattgca ggatctttcg
     8161 gtgacattca ttacaataat gaactcaata atggcatgtt gccaatcgtt cagcctagag
     8221 aggttagaga gaaactagcc cagctaaaac caaccgacca ggtaactgtg gacttggaac
     8281 aacaaaaaat catctcacca gttgaagaat tcaccttcga gatagatagc gagtggaaac
     8341 ataaactcct aaatagtttg gatgatatcg gtattacctt gcagtatgaa gagttgattg
     8401 ctgcttatga aaaacaacga ccagcctact ggcaggatta gaaaaaatag aaaaggagat
     8461 atagtaaact gaaataagat gtaaacaaat gaattggagc ttaacatcca tttccagcaa
     8521 ttttttagaa actacagtgg actattctgg attcaacaca ttataaaatt atgacaaaac
     8581 acattcacaa gaaggctacg acattttaaa aggtgagggc ggatgtatcg tttgccctac
     8641 taaagttggt tacattatca tgaccagcaa caaggcagga cttgagcgta agttcgcagc
     8701 caaagaacgt aagcgtaaca aaccaggtgt tgttctctgc ggtagcatgg atgaactttg
     8761 cgctttagcg caactcaacc cagaaattga agcattctac taaaaacatt gggatgaaga
     8821 tattcttctt ggttgtatcc ttccttggaa accagaagcc tttgaaaaac tcaaagcata
     8881 cggggatggc cgtgaagaac ttatgactga tgtacgtggt actagctgtt ttgttatcaa
     8941 gtttggaaaa gcaggtgaac aattggctgc caagctttgg gaagaaggta aaatggtcta
     9001 cgcctcatct gcttcaatga caaaacgact gaaactcgct atgagcaagg tgtaatggtg
     9061 tctatggtcg ataaggacgg caaactcatc ccagaacaag gaggagcacg ttcaacttca
     9121 ccagcaccag ttgtgatccg taaagggctt gacattgata aaatcatgat gcacctgtca
     9181 gatactttta actcatggaa ctaccgtcag gttgagtatt attaagataa aaaaagaagt
     9241 ctagtgttat gagatattaa agctcctaac actggacttt ttgtttagaa tttcttttct
     9301 ttttctatag gatatggtat tctatgtaga aaatatatgt taataagtaa tgccaatatt
     9361 taaacatcat tagtaaaagg agttagattg atgaataaaa gaaaagttag tttagaagat
     9421 ttttataaat ggtatagtct aaataaagaa gagttattaa ataaggcaac tgttggtgaa
     9481 aagtttaatg ataaattaaa agaagagttt ctccaggaat ggcctttgga taggatttta
     9541 acaatgtcaa tcgatgaata tgtaatagga aagggacagc aaaataagtc tttatgctac
     9601 gctcttgaga agggaaaata caaaaatcta tttcttggaa tttctggtgg ctcagcttca
     9661 aaatttggta tttattggaa taaaaaaaca aacaaatata aagatcaagc taataatgag
     9721 atttcagagt tggatcagcg attttcaaaa ttaaaatcag atttgtatga aattatcaaa
     9781 gaaggtattc gttttaactt tgaaaattct atttttgata tgaaaagatc aacaaatgaa
     9841 tttattggtc gttctgctat ggtgacaaaa ttactttgta tctattctga gggagatcct
     9901 ttctttggtg taaatattaa tagtcagaaa gaattttgga accactttgt ttctcagaca
     9961 aatcaaggtg gaccttatct gcaaaatcat aaaataattg aactggtgtc caaaacttat
    10021 cctgagttgg agccatcgaa attaggaact atgctttttg agtattctaa gctttttatg
    10081 gaaaataagg aagacaatag tacaatggat tcatcaaaca attttcgtca tcaattaact
    10141 caatctctat taaagtctcc aaaccttatc cttcgtggtg ctcctggcac aggaaagact
    10201 tatcttgcta aagaaattgc caaagaatta acggatggca acgaagatca aatcggattt
    10261 gtacaatttc acccatcata tgattatacg gattttgtag aaggtttaag accagtatca
    10321 aatggggatg gagctattga gtttaggcta caggacggta tttttaaaga tttttgtcag
    10381 aaagcaaaag aaacccaatt gattggagga caagataatt ttgatgaggc ttgggattct
    10441 tacttagaat atataaatgt tgctgaagaa aaagaatata taacaaaaac atcttactta
    10501 tctgttaata gtagacaaaa tttgtcagta aattatgata gtggtgttcc aggatggtca
    10561 ctacctagca aatatgttta cgagttgtat aaagataaaa attataataa gcaagaatac
    10621 tacaaaagtg gtggaaaaac tgtcctagaa acattgagaa agagatttgg tttgaaagac
    10681 tatgtttccc caacagaaat tgatactgat aagaaattcg tcttcatcat cgatgaaatc
    10741 aatcgtgggg agatttctaa gatttttggc gaactctttt tctctatcga ccctggctat
    10801 cgtggtgaaa aaggaagtgt ttctacccaa tatgcaaatc tacacgaaac tgatgaaaag
    10861 ttctatatcc ccgaaaatgt ttacatcatc ggaactatga atgatattga tcgttcagtg
    10921 gatacctttg attttgctat gcgtcgtcgt tttcgttttg ttgaagttac tgccgagggt
    10981 caagttggca tgttggataa agagctgaat atccatgcag aagaagcaaa aattcgtctc
    11041 agaaacttga acgctgctat cgaaaatgtt caggaattaa acagtcatta tcatattgga
    11101 ccaagttatt ttcttaagtt gaaggatgta gattttgact atgaattact ctggtctgat
    11161 tatattaagc ctctcctaga agactacttg cgaggttctt atgatgaggt tgaaactttg
    11221 gaaactttga aaaaagcatt tgaactgaca aataatgagc aaaaagatca ggcagtagct
    11281 gatgacaatg aaagcgatga aaacgatgat gcggattact gataatcaac acaagattat
    11341 taaagaaaaa tttgttgaag aatatcctaa actaagcaat cttcttttag acagaacctt
    11401 ggaaagtcta tcccaagatg aacgtatttt catttttcca aatgatttga ctcatactcc
    11461 agatttggat aagaaacaaa agattttgga aacgatcaat caggaaatca agacaggaaa
    11521 tgtgattggt tttcttggat atggtcagga aagattaacg atttcctcac gattttctga
    11581 tgagagtaat gaccattttt tgcattatct cttaaacaag gttcttcata tcaatctcac
    11641 tagtttagat gttgctttgt ctcgtgaaga gaggctttat caacttttga tgtatctctt
    11701 ccccaagtat ctacaagctg ctattcgaaa aggtctttat aaggaatatc atcgattttc
    11761 tcataacgac agtcatgtta agggagtgat tgatgtaaga aaccatctca agaaaaatct
    11821 tcctttcacg ggaaatattg cctacacaac gagagagttc acctatgata atcccctcat
    11881 gcagttggtc cgtcacacta ttgaatacat taagaatcag aaaagcattg gtcaaggggt
    11941 actagataat ctctcaacta gtcgtgaaaa cgtatctgaa atcgtgcgtg taacgccctc
    12001 ttataaacta gctgatcgtg ctaagattat tcggggaaat caatctaaac ctatacgtca
    12061 tgcatacttt cacgagtaca gaaatttaca agaactttgt ctgatgatcc taaaccaaga
    12121 aaagcacggt ttagggtatc aagatcaaaa aatctatggt attctctttg atgttgcctg
    12181 gctttgggaa gagtatgttt acaccttgtt gccaaaaggt tttgtacatc ccagaaataa
    12241 ggataagacg gatggaattt cagtattttc tgttgggaaa cgaaaagtat atccagattt
    12301 ttatgacaga gaacgaaaga ttgttctaga tgcaaaatat aaaaaactgg aattgactga
    12361 aaaaggaatc aaccgtgagg acttattcca gctgatttcc tattcttata ttttaaaagc
    12421 tgagaaggct ggacttgttt ttccgagcaa ggacaaggtc attgataatg agataggaaa
    12481 cctagcaggt tatggagctt tgttgaagaa atggtctatc caaattcctc agaagtcttc
    12541 atcttatagt gcattttgta aaatgatgga aaattcagaa gaaaatttta aagcgattat
    12601 tgatgaagaa gtggggagaa aataatttcc cctctttctt ttatttttaa cacaagc
//
LOCUS       DAVLTT010000053        12540 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLTT010000053 DAVLTT010000000
VERSION     DAVLTT010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12540
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.053"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..1070
                     /gene="dnaN"
                     /locus_tag="VYN15_001649"
     CDS             <1..1070
                     /gene="dnaN"
                     /locus_tag="VYN15_001649"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV1452941.1"
                     /translation="SKNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNEDAGL
                     LITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQYPR
                     IQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDSH
                     RLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIEAVEIFFANNQILFRSENISFY
                     TRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVV
                     SAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRPF
                     TLVPADTDEDFMQLITPVRTN"
     gene            1135..1329
                     /locus_tag="VYN15_001650"
     CDS             1135..1329
                     /locus_tag="VYN15_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV1452942.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            1413..2528
                     /gene="ychF"
                     /locus_tag="VYN15_001651"
     CDS             1413..2528
                     /gene="ychF"
                     /locus_tag="VYN15_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV1452943.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            2599..3168
                     /locus_tag="VYN15_001652"
     CDS             2599..3168
                     /locus_tag="VYN15_001652"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV1452944.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVKYYLQEKNFEKTMQRYNG"
     gene            3169..6678
                     /gene="mfd"
                     /locus_tag="VYN15_001653"
     CDS             3169..6678
                     /gene="mfd"
                     /locus_tag="VYN15_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV1452945.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            6736..7002
                     /locus_tag="VYN15_001654"
     CDS             6736..7002
                     /locus_tag="VYN15_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV1452946.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            6995..7363
                     /locus_tag="VYN15_001655"
     CDS             6995..7363
                     /locus_tag="VYN15_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV1452947.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            7483..8751
                     /locus_tag="VYN15_001656"
     CDS             7483..8751
                     /locus_tag="VYN15_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV1452948.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLLQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            8748..10025
                     /gene="tilS"
                     /locus_tag="VYN15_001657"
     CDS             8748..10025
                     /gene="tilS"
                     /locus_tag="VYN15_001657"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV1452949.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIKNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            10029..10571
                     /gene="hpt"
                     /locus_tag="VYN15_001658"
     CDS             10029..10571
                     /gene="hpt"
                     /locus_tag="VYN15_001658"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV1452950.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            10587..>12540
                     /gene="ftsH"
                     /locus_tag="VYN15_001659"
     CDS             10587..>12540
                     /gene="ftsH"
                     /locus_tag="VYN15_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV1452951.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT         4310 a         1886 c         2561 g         3783 t
ORIGIN      
        1 gttctaaaaa tgccattcct attttatcaa cagtaaaaat tgacgtgacc aatgaaggta
       61 ttactttaat tggttcaaat ggtcaaattt caattgaaaa ttttatttct caaaaaaatg
      121 aagatgctgg tttgttaatt acttctttag gttcgatcct tcttgaagct tctttcttta
      181 tcaatgtagt atctagttta cctgatgtaa ctcttgattt taaagaaatt gaacaaaatc
      241 aaattgtttt aaccagtggc aaatcagaaa ttaccctaaa aggaaaagat agcgaacaat
      301 atccacgaat ccaagaaatt tcagcaagca ctcctttaat acttgaaaca aaattactca
      361 agaaaattat taatgaaaca gcctttgctg caagtacaca agagagtcgt ccgattttaa
      421 caggtgtcca cttcgtattg agtcaacaca aagagttaaa aacagttgca acagactctc
      481 atcgcctaag ccagaaaaaa ttgactcttg aaaaaaatag tgatgatttt gatgtcgtaa
      541 ttcctagccg ttctctacgc gaattttcag cggtatttac agatgatatc gaagctgtag
      601 agattttctt tgccaataac caaatcctct ttagaagcga aaatattagc ttctatactc
      661 gtctcctaga aggaaactat cctgatacag atcgcttgat tccaacagac tttaacacta
      721 ctattacttt taatgtggta aacttacgcc agtcaatgga gcgtgcccgt cttttatcaa
      781 gtgcgactca aaatggtact gtgaaacttg aaattaagga tggggttgtt agcgcccatg
      841 ttcactctcc agaagttggt aaagtaaacg aagaaatcga tactgatcag gttactggtg
      901 aagatttgac cattagtttc aacccaactt acttgattga ttctcttaaa gctttaaata
      961 gcgaaaaggt gaccattagc tttatctcag ctgttcgtcc atttactctt gtgccagcag
     1021 atactgacga agacttcatg cagctcatta caccagttcg tacaaattaa gtgaaagagg
     1081 ttgagcctgg ctcgcctctt ttatgatata atcgaaaaag aaaaggagag tagtatgtat
     1141 caagttggaa attttgttga gatgaaaaaa tcacacgctt gtacaatcaa gtcgactggt
     1201 aaaaaggcta atcgttggga aattacacgt gtaggagcag atatcaaaat aaaatgcagt
     1261 aattgtgagc atgttgtcat gatggggcga tatgattttg agcgaaaaat gaataaaatt
     1321 attgactgag aacccttagt tagagggtta gcactttatc cctttttgtg ttataatatt
     1381 agggattgaa atgaaaacgg agaatgagaa atatggcttt gacagcaggt atcgttggtt
     1441 tgccaaacgt tggtaaatca acactattta atgcaattac aaaagcagga gcagaggcag
     1501 caaactaccc atttgcgact attgatccaa atgttggaat ggtggaagtt ccagatgaac
     1561 gcctacaaaa actaactgaa atgataactc ctaaaaagac agttcccaca acatttgaat
     1621 ttacggatat tgcagggatt gtaaaaggag cttcaaaagg agaagggcta gggaataaat
     1681 tcttggccaa tattcgtgaa gtagatgcga ttgttcacgt agttcgtgct tttgatgatg
     1741 aaaatgtgat gcgcgagcaa ggacgtgaag acgcctttgt agatccactt gcagatattg
     1801 atacaattaa tctggaatta attcttgctg acttagaatc agtgaacaaa cgatatgcgc
     1861 gtgtagaaaa gatggcacgt acgcaaaaag ataaagaatc agtagcagaa ttcaatgttc
     1921 ttcaaaagat taaaccagtc ctagaagacg ggaaatcagc tcgtaccatt gaatttacag
     1981 atgaggaaca aaaggttgtc aaaggtcttt tccttttgac gactaaacca gttctttatg
     2041 tagctaatgt ggacgaggat gtggtttcag aacctgactc tatcgactat gtcaaacaaa
     2101 ttcgtgaatt tgcagcgaca gaaaatgctg aagtagtcgt tatttctgcg cgtgctgagg
     2161 aagaaatttc tgaattggat gatgaagata aaaaagagtt tcttgaagca attggtttga
     2221 cagaatcagg tgtagataag ttgacgcgtg cagcttacca cttgcttgga ttgggaactt
     2281 acttcacagc tggtgaaaaa gaagttcgcg cttggacttt caaacgtggt atgaaggctc
     2341 ctcaagcagc tggtattatc cactcagact ttgaaaaagg ctttattcgt gcagtaacca
     2401 tgtcatatga agatctagtg aaatacggat ctgaaaaggc cgtaaaagaa gctggacgct
     2461 tgcgtgaaga aggaaaagaa tatatcgttc aagatggcga tatcatggaa ttccgcttta
     2521 atgtctaaaa attaataaat ggtgtcaatt aggttggaaa aaaattccaa cccttttggc
     2581 ttttgaaagg aaaaataaat gaccaaatta cttgtaggct tgggaaatcc aggggataaa
     2641 tattttgaaa caaaacacaa tgttggtttt atgttgattg atcaactagc gaagaaacag
     2701 aatgtcactt ttacacacga taagatattt caagctgacc tagcatcctt tttcctaaat
     2761 ggagaaaaaa tttatctggt taaaccaacg acctttatga atgaaagtgg aaaagcagtt
     2821 catgctttat taacttacta tggtttggat attgacgatt tacttatcat ttacgatgat
     2881 cttgacatgg aagttgggaa aattcgttta agagcaaaag gctcagcagg tggtcataat
     2941 ggtatcaagt ctattattca acatatagga actcaggtct ttaaccgtgt taagattgga
     3001 attggaagac ctaaaaatgg tatgtcagtt gttcatcatg ttttgagtaa gtttgacagg
     3061 gatgattata tcggtatttt acagtctgtt gacaaagttg acgattctgt aaaatactat
     3121 ttacaagaga aaaattttga gaaaacaatg cagaggtata acggataaat ggtgacctta
     3181 ttagatttat tctcagaaaa tgatcagatt aaaaaatggc atcaaaattt aacagataag
     3241 aaaagacaac taatacttgg tttatcaaca tctactaagg ctcttgcaat tgcaagcagt
     3301 ttagaaaaag aagataggat tgtgttattg acgtcaactt atggagaagc agaaggactt
     3361 gttagtgatc ttatttctat cttgggtgag gaactcgtct atccattttt ggtagatgat
     3421 gctcctatgg tggagttttt gatgtcttca caggaaaaaa ttatttcacg ggttgaagcc
     3481 ttgcgttttt tgactgattc atctaagaaa gggattttag tttgtaatat cgcagcaagt
     3541 cgattgattt taccgtctcc caatgcattc aaagatagta ttgtaaaaat ctcagttggt
     3601 gaagaatatg atcaacacgc gtttatccat cagttaaagg aaaatggcta tcgaaaagtt
     3661 actcaagtac aaactcaggg cgaatttagt cttcgaggag atattttaga tatttttgaa
     3721 atatcccagt tagaaccttg tcgaattgag ttttttggtg atgaaattga tggtatcagg
     3781 tcatttgaag tagaaacaca attatcgaaa gaaaataaga cagaactcac tatctttcca
     3841 gctagtgata tgcttttgag agaaaaggat tatcaacgag gacagtcagc tttagaaaaa
     3901 caaatttcaa aaactttatc acctattttg aaatcatacc tagaagaaat tctttcaagt
     3961 tttcaccaaa aacaaagtca tgcagactct cggaagtttt tatctttgtg ctatgataag
     4021 acatggactg tctttgatta tattgaaaaa gatactccaa tattctttga tgattatcaa
     4081 aaattgatga atcagtatga agtctttgaa agagacttag cacagtactt tacagaagaa
     4141 ttacagaata gtaaagcatt ttctgatatg cagtattttt ctgatattga acaaatctat
     4201 aaaaaacaaa gtccagtgac ctttttctct aatcttcaaa agggtttagg aaatctcaaa
     4261 tttgacaaaa tttatcaatt caatcaatat cctatgcagg aatttttcaa tcagttttct
     4321 tttctaaaag aagaaattga acgatataaa aaaatggatt acaccattat tctgcagtct
     4381 agcaattcaa tgggaagtaa aacattggag gatatgttag aggaatatca gattaaattg
     4441 gattctagag ataagacaag tatctgtaaa gaatctgtaa acttaataga gggtaatctc
     4501 agacatggtt ttcattttgt agatgaaaag attttattga taactgaaca tgagattttt
     4561 caaaagaaat taaagcgtcg ttttcgaaga caacatgttt caaatgcaga gagattaaaa
     4621 gattacaatg aacttgaaaa aggggactat gttgtccatc atatccatgg gattggtcaa
     4681 tatctaggaa ttgaaaccat tgaaatcaag ggaattcatc gcgattatgt cagtgtccaa
     4741 taccaaaatg gtgatcaaat ttctatcccc gtggaacaga ttcatctact gtccaaatat
     4801 atttcaagtg atggtaaagc tccaaaactc aataaattaa atgacggtca ttttaaaaag
     4861 gccaagcaaa aggttaagaa ccaggtagag gatatagctg atgatttaat caaactctac
     4921 tctgaacgta gtcagttgaa gggttttgct ttctcagctg atgatgatga tcaagatgcc
     4981 tttgatgatg ctttccctta tgttgaaacg gatgatcaac ttcgtagtat tgaggaaatc
     5041 aagagggata tgcaggcttc tcagccaatg gatcgacttt tagttgggga tgttggtttt
     5101 ggaaagactg aagttgctat gcgtgcagcc tttaaagcag tcaatgatca caaacaggtt
     5161 gtcattctag ttccgacgac ggttttagcg caacagcact atacgaattt taaggaacga
     5221 ttccaaaatt ttgcagttaa tgttgatgtg ttgagtcgct ttagaagtaa aaaagagcag
     5281 actgcaacac ttgaaaaatt gaaaaacggt caagtcgata ttttgattgg aacacatcgt
     5341 gttttgtcaa aagatgttgt gtttgctgat ttgggcttga tgattattga tgaggaacag
     5401 cgatttggtg tcaagcataa ggaaactttg aaagaactga agaaacaagt ggatgtccta
     5461 accttgaccg ctacgccaat ccctcgtacc ctccatatgt ctatgctggg aatcagagat
     5521 ttgtctgtta ttgaaactcc gccgactaat cgctatcctg ttcagaccta tgttttggaa
     5581 aagaatgata gtgtcattcg tgatgctgtc ttgcgtgaaa tggagcgtgg aggtcaagtt
     5641 tactatcttt acaacaaagt tgacacaatt gttcagaagg tttcagaatt acaggagttg
     5701 attccggagg cttcgattgg atatgttcat ggtcgaatga gtgaagtcca gttggaaaat
     5761 actctattag actttattga gggacaatac gatatcttgg tgacgactac tattattgag
     5821 acaggggtgg acattccaaa tgctaatact ttatttattg aaaatgcgga ccatatgggc
     5881 ttgtcaacct tatatcagtt aagaggaaga gtcggtcgta gtaatcgtat tgcttatgct
     5941 tatctcatgt atcgtccaga aaaatcaatc agtgaagtct ctgaaaagag attagaagcg
     6001 attaaaggat ttacagaatt gggctctggc tttaagattg caatgcgaga tctttcgatt
     6061 cgtggagcag gaaatctttt aggaaaatcc cagtctggtt tcattgattc tgttggtttt
     6121 gaattgtatt cgcagttatt agaggaagct attgctaaac gaaacggtaa tgctaacgct
     6181 aacacaagaa ccaaagggaa tgctgagttg attttgcaaa ttgatgccta tcttcctgat
     6241 acttatattt ctgatcaacg acataagatt gaaatttaca agaaaattcg tcaaattgac
     6301 aaccgtgtca attatgaaga gttacaagag gagttgatag accgttttgg agaataccca
     6361 gatgtagtag cctatctttt agagattggt ttggttaaat catacttgga caaggtcttt
     6421 gttcaacgtg tggaaagaaa agataataaa attacaattc aatttgaaaa agtcactcaa
     6481 cgactgtttt tagctcaaga ttattttaaa gctttatccg taacgaactt aaaagcaggc
     6541 atcgctgaga ataagggatt aatggagctt gtatttgatg tccaaaataa gaaagattat
     6601 gaaattttag aaggtttgct gatttttgga gaaagtttat tagagataaa agagtctaag
     6661 gaagaaaatt ccatttgata tttttcttct ataaaataga taaaaatggt acaataataa
     6721 attgaggtaa taaggatgag attagataaa tatttaaaag tatcgcgaat tatcaagcgt
     6781 cgtacagtcg caaaggaagt agcagataaa ggtagaatca aggttaatgg aatcttggcc
     6841 aaaagttcaa cggacttgaa agttaatgac caagttgaaa ttcgctttgg caataagttg
     6901 ctgcttgtaa aagtactaga gatgaaagat agtacaaaaa aagaagatgc agcaggaatg
     6961 tatgaaatta tcagtgaaac acgggtagaa gaaaatgtct aaaaatattg tacaattgaa
     7021 taattctttt attcaaaatg aataccaacg tcgtcgctac ctgatgaaag aacgacaaaa
     7081 acggaatcgt tttatgggag gggtattgat tttgattatg ctattattta tcttgccaac
     7141 ttttaattta gcgcagagtt atcagcaatt actccaaaga cgtcagcaat tagcagactt
     7201 gcaaactcag tatcaaactt tgagtgatga aaaggataag gagacagcat ttgctaccaa
     7261 gttgaaagat gaagattatg ctgctaaata tacacgagcg aagtactatt attctaagtc
     7321 gagggaaaaa gtttatacga ttcctgactt gcttcaaagg tgataaaatg gaaaatttat
     7381 tagacgtaat agagcaattt ttgagtttgt cagatgaaaa gctggaagaa ttggctgata
     7441 aaaatcaatt attgcgttta caagaagaaa aggaaaggaa gaatgcgtaa attcttaatt
     7501 attttgttgc taccaagttt tttgaccatt tcaaaagtcg ttagcacaga aaaagaagtc
     7561 gtctatactt cgaaagaaat ttattacctt ttacaatctg actttggtat ttattttaga
     7621 gaaaaattaa gttctcccat ggtttatgga gaggttcctg tttatgcgaa tgaagattta
     7681 gtagtggaat ctgggaaatt gactcccaaa acaagttttc aaataaccga gtggcgctta
     7741 aataaacaag gaattccagt atttaagcta tcaaatcatc aatttatagc tgcggacaaa
     7801 cgatttttat atgatcaatc agaggtaact ccaacaataa aaaaagtatg gttagaatct
     7861 gactttaaac tgtacaatag tccttatgat ttaaaagaag tgaaatcatc cttatcagct
     7921 tattcgcaag tatcaatcga caagaccatg tttgtagaag gaagagaatt tctacatatt
     7981 gatcaggctg gatgggtagc taaagaatca acttctgaag aagataatcg gatgagtaaa
     8041 gttcaagaaa tgttatctga aaaatatcag aaagattctt tctctattta tgttaagcaa
     8101 ctgactactg gaaaagaagc tggtatcaat caagatgaaa agatgtatgc agccagcgtt
     8161 ttgaaactct cttatctcta ttatacgcaa gaaaaaataa atgagggtct ttatcagtta
     8221 gatacgactg taaaatacgt atctgcagtc aatgattttc caggttctta taaaccagag
     8281 ggaagtggta gtcttcctaa aaaagaagat aataaagaat attctttaaa ggatttaatt
     8341 acgaaagtat caaaagaatc tgataatgta gctcataatc tattgggata ttacatttca
     8401 aaccaatctg atgccacatt caaatccaag atgtctgcca ttatgggaga tgattgggat
     8461 ccaaaagaaa aattgatttc ttctaagatg gccgggaagt ttatggaagc tatttataat
     8521 caaaatggat ttgtgctaga gtctttgact aaaacagatt ttgatagtca gcgaattgcc
     8581 aaaggtgttt ctgttaaagt agctcataaa attggagatg cggatgaatt taagcatgat
     8641 acgggtgttg tctatgcaga ttctccattt attctttcta ttttcactaa gaattctgat
     8701 tatgatacga tttctaagat agccaaggat gtttatgagg ttctaaaatg agggaaccag
     8761 attttttaaa tcattttctc aagaagggat atttcaaaaa gcatgctaag gcggttctag
     8821 ctctttctgg tggattagat tccatgtttc tatttaaggt attgtctact tatcaaaaag
     8881 agttagagat tgaattgatt ctagctcatg tgaatcataa gcagagaatt gaatcagatt
     8941 gggaagaaaa ggaattaagg aagttggctg ctgaagcaga gcttcctatt tatatcagca
     9001 atttttcagg agaattttca gaagcgcgtg cacgaaattt tcgttatgat ttttttcaag
     9061 aggtcatgaa aaagacaggt gcgacagctt tagtcactgc ccaccatgct gatgatcagg
     9121 tggaaacgat tttgatgcgc ttgattcgag gaactcgctt gcgctatcta tcaggaatta
     9181 aggagaagca agtagtcgga gagatagaaa tcattcgtcc cttcttgcat tttcagaaaa
     9241 aagactttcc atcaattttt cactttgaag atacatcaaa tcaggagaat cattattttc
     9301 gaaatcgtat tcgaaattct tacttaccag aattggaaaa agaaaatcct cgatttaggg
     9361 atgcaatctt aggcattggc aatgaaattt tagattatga tttggcaata gctgaattat
     9421 ctaacaatat taatgtggaa gatttacagc agttattttc ttactctgag tctacacaaa
     9481 gagttttact tcaaacttat ctgaatcgtt ttccagattt gaatcttaca aaagctcagt
     9541 ttgctgaagt tcagcagatt ttaaaatcta aaagccagta tcgtcatccg attaaaaatg
     9601 gctatgaatt gataaaagag taccaacagt ttcagatttg taaaatcagt ccgcaggctg
     9661 atgaaaagga agatgaactt gtgttacact atcaaaatca ggtagcttat caaggatatt
     9721 tattttcttt tggacttcca ttagaaggtg aattaattca acaaatacct gtttcacgtg
     9781 aaacatccat acacattcgt catcgaaaaa caggagatgt tttgattaaa aatgggcata
     9841 gaaaaaaact cagacgttta tttattgatt tgaaaatccc tatggaaaag agaaactctg
     9901 ctcttattat tgagcaattt ggtgaaattg tctcaatttt gggaattgcg accaataatt
     9961 tgagtaaaaa aacgaaaaat gatataatga acactgtact ttatatagaa aaaatagata
    10021 ggtaaaaaat gttagaaaac gatattaaaa aagtcctcgt ttcacacgat gaaattacag
    10081 aagcagctaa aaaactaggt gctcaattaa ctaaagacta tgcaggaaaa aatccaatct
    10141 tagttgggat tttaaaagga tctattcctt ttatggctga attggtcaaa catattgata
    10201 cacatattga aatggacttc atgatggttt ctagctacca tggtggaaca gcaagtagtg
    10261 gtgttatcaa tattaaacaa gatgtgactc aagatatcaa aggaagacat gttctatttg
    10321 tagaagatat cattgataca ggtcaaactt tgaagaattt gcgagatatg tttaaagaaa
    10381 gagaagcagc ttctgttaaa attgcaacct tgttggataa accagaagga cgtgttgtag
    10441 aaattgaggc agactatacc tgctttacta tcccaaatga gtttgtagta ggttatggtt
    10501 tagactacaa agaaaattat cgtaatcttc cttatattgg agtattgaaa gaggaagtgt
    10561 attcaaatta gaaagaataa tctttaatga aaaaacaaaa taatggttta attaaaaatc
    10621 cttttctatg gttattattt atctttttcc ttgtgacagg attccagtat ttctattctg
    10681 ggaataactc aggaggaagt cagcaaatca actatactga gttggtacaa gaaattaccg
    10741 atggtaatgt aaaagaatta acttaccaac caaatggtag tgttatcgaa gtttctggtg
    10801 tctataaaaa tcctaaaaca agtaaagaag gaacaggtat tcagtttttc acgccatctg
    10861 ttactaaggt agagaaattt accagcacta ttcttcctgc agatactacc gtatcagaat
    10921 tgcaaaaact tgctactgac cataaagcag aagtaactgt taagcatgaa agttcaagtg
    10981 gtatatggat taatctactc gtatccattg tgccatttgg aattctattc ttcttcctat
    11041 tctctatgat gggaaatatg ggaggaggca atggccgtaa tccaatgagt tttggacgta
    11101 gtaaggctaa agcagcaaat aaagaagata ttaaagtaag attttcagat gttgctggag
    11161 ctgaggaaga aaaacaagaa ctagttgaag ttgttgagtt cttaaaagat ccaaaacgat
    11221 tcacaaaact tggagcccgt attccagcag gtgttctttt ggagggacct ccggggacag
    11281 gtaagacttt gcttgctaag gcagtcgctg gagaagcagg tgttccattc tttagtatct
    11341 caggttctga ctttgtagaa atgtttgtcg gagttggagc tagtcgtgtt cgctctcttt
    11401 ttgaggatgc caaaaaagca gcaccagcta tcatctttat cgatgaaatt gatgctgttg
    11461 gacgtcaacg tggagttggt ctcggcggag gtaatgacga acgtgaacaa accttgaacc
    11521 aacttttgat tgagatggat ggttttgagg gaaatgaagg gattatcgtc atcgctgcga
    11581 caaaccgttc agatgtactt gatcctgccc ttttgcgtcc aggacgtttt gatagaaaag
    11641 tattggttgg ccgtcctgat gttaaaggtc gtgaagcaat cttgaaagtt cacgctaaga
    11701 acaagccttt agcagaagat gttgatttga aattagtggc tcaacaaact ccaggctttg
    11761 ttggtgctga tttagagaat gtcttgaatg aagcagcttt agttgctgct cgtcgcaata
    11821 aatcgataat tgatgcttca gatattgatg aagcagaaga tagagttatt gctggacctt
    11881 ctaagaaaga taagacagtt tcacaaaaag aacgagaatt ggttgcttac catgaggcag
    11941 gacataccat tgttggtcta gtcttgtcga atgctcgcgt tgtccataag gttacaattg
    12001 taccacgcgg ccgtgcaggc ggatacatga ttgcacttcc taaagaggat caaatgcttc
    12061 tatctaaaga agatatgaaa gagcaattgg ctggcttaat gggtggacgt gtagctgaag
    12121 aaattatctt taatgtccaa actacaggag cttcaaacga ctttgaacaa gcgacacaaa
    12181 tggcacgtgc aatggttaca gagtacggta tgagtgaaaa acttggccca gtacaatatg
    12241 aaggaaacca tgctatgttt ggtgcacaga atcctcaaaa atcaatttca gaacaaacag
    12301 cttatgaaat tgatgaagag gttcgttcat tattaaatga ggcacgaaat aaagctgctg
    12361 aaattattca gtcaaatcgt gaaactcaca agttaattgc agaagcatta ttgaaatacg
    12421 aaacattgga tagtacacaa attaaagctc tttacgaaac aggaaagatg cctgaagcag
    12481 tagaagagga atctcatgca ctatcctatg atgaagtaaa gtcaaaaatg aatgacgaaa
//
LOCUS       DAVLTT010000054        12059 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLTT010000054 DAVLTT010000000
VERSION     DAVLTT010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12059
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.054"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            241..894
                     /locus_tag="VYN15_001660"
     CDS             241..894
                     /locus_tag="VYN15_001660"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV1452952.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGTIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            904..1368
                     /locus_tag="VYN15_001661"
     CDS             904..1368
                     /locus_tag="VYN15_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1452953.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1381..2649
                     /locus_tag="VYN15_001662"
     CDS             1381..2649
                     /locus_tag="VYN15_001662"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV1452954.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2663..2923
                     /locus_tag="VYN15_001663"
     CDS             2663..2923
                     /locus_tag="VYN15_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452955.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2934..4295
                     /gene="pdrM"
                     /locus_tag="VYN15_001664"
     CDS             2934..4295
                     /gene="pdrM"
                     /locus_tag="VYN15_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV1452956.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4449..5417
                     /locus_tag="VYN15_001665"
     CDS             4449..5417
                     /locus_tag="VYN15_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV1452957.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5433..6425
                     /locus_tag="VYN15_001666"
     CDS             5433..6425
                     /locus_tag="VYN15_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV1452958.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVVPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            6643..7686
                     /locus_tag="VYN15_001667"
     CDS             6643..7686
                     /locus_tag="VYN15_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV1452959.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGKIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFDPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7750..9435
                     /gene="lpdA"
                     /locus_tag="VYN15_001668"
     CDS             7750..9435
                     /gene="lpdA"
                     /locus_tag="VYN15_001668"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV1452960.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9499..10488
                     /locus_tag="VYN15_001669"
     CDS             9499..10488
                     /locus_tag="VYN15_001669"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV1452961.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANITESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10563..11633)
                     /gene="xerS"
                     /locus_tag="VYN15_001670"
     CDS             complement(10563..11633)
                     /gene="xerS"
                     /locus_tag="VYN15_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV1452962.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
BASE COUNT         3593 a         2246 c         2681 g         3539 t
ORIGIN      
        1 ttctgaaatg gattttaata tgtttaaaaa tatttcagaa aagataatct tcgaaagagg
       61 tagtaaaatg cttaatgatt taaaaagtaa ttataaaaaa tagccagtct ttataaactg
      121 tattcacgta ttcaaatcgt atatatagtc gatttattaa atctttagat aaactgtaaa
      181 aagtggtttc catagccact ttttgctata atagaggcag taaaaatgaa ggagttggct
      241 atggaacact cgtcttggca cgctttgatt aaggcgcaat tacctgaggg ttatttcggg
      301 aaaatcaatc agtttatgga gcaggtctat tctcagggga ctatttatcc acccaaggaa
      361 aaggtttttc aggctctctt gacaacactg cttgaagaag ttaaggtggt aattctaggg
      421 caagacccct accacggacc aggtcaagcg cagggcttga gtttttctgt acctgactct
      481 atcccagctc caccatcctt gcaaaatatc ttgaaagaat tgtcagatga tatcggagtt
      541 aagaaatctc atgatttgac agcttgggct gagcaaggag tcttgcttct taatgcttgt
      601 ttgactgttc ctgctggaca ggccaatggt catgctggtc aaatctggga gccttttact
      661 gatgctgtga ttcaggtggt caatcatcta gatagaccag tcgtttttgt actctgggga
      721 gcttatgcac gtaagaagaa ggcattagtt accaatcctc atcacttgat tatcgaatca
      781 gcccatccaa gtcctttgtc ggtttataga ggattttggg gttccaagcc cttttccaag
      841 gccaatgcat tcttaaaaga gacaggacaa gagccaatcg attggcttag ataaggagaa
      901 aatatgcctc agttagcgac gatttgctac attgataatg ggaaagaact gctcatgctc
      961 catcgtaata agaaacccaa tgatgtccat gaagggaaat ggattggtgt gggtggtaag
     1021 ctagagagag gagagacgcc ccaggaatgc gcggcgcgtg aaatccttga agaaacaggg
     1081 ctcaaagcca agccagttct aaaaggtgtc atcacttttc ctgaatttac accagattta
     1141 gactggtaca cctatgtttt taaggtgacg gagtttgagg gcgacttgat tgactgcaat
     1201 gaggggacgc tagaatgggt tccctatgat gaggttttga gcaagccgac ttgggaaggt
     1261 gaccacacct ttgttgagtg gcttttagag gataaaccct tcttttcagc caagtttgtt
     1321 tatgatgggg ataaattgtt ggatacccaa gttgatttct atgaataaag gagaaagcag
     1381 atgctactaa tcaaaaatgg tcgtgtaatg gatcctaagt ctggtttgga tcaagtttgt
     1441 gatgtcttag ttcaagatgg gaaaattatc aaaattgcgc ctgagatcac ggaagaagga
     1501 gcagaaacga ttgatgctac tggtcttgtg gttgctcctg gtttggtcga tattcatgtg
     1561 catttccgtg aacctggtca aacacataaa gaagacattc atactggtgc cctggcagcc
     1621 gctgcaggtg gttttactac tgtcgtcatg atggctaata ccagtccaac catttcagac
     1681 gtggagactt tgcaagcagt tctccagtca gctgccaaag agaagattaa tgtcaagaca
     1741 gttgcgacca ttactaaaaa ctttaatggt aaaaacttga ctgactttaa ggcgctctta
     1801 gaagctggtg cggttggttt ctctgatgac ggtattccgc ttgagagcag taagattgtc
     1861 aaggaagcca tggaggaagc caaaaaactc aataccttta tcagccttca tgaggaagat
     1921 ccaggtttga acggtgttct tggctttaat gaaaatattg ctagagaaca tttccatatc
     1981 tgcggtgcta ctggggtggc tgagtacgct atgatggcgc gtgatgtcat gattgcctat
     2041 gcaactaaag cccatgttca catccagcat ttgtctaagg aagaaagtgt taaagtagtg
     2101 gagtttgctc aggggttagg tgcagaagtc acagcagaag tagcaccaca gcatttctct
     2161 aagacagaag cacttctttt aacacaaggt agcaatgcta agatgaatcc accgcttcgt
     2221 ttggaatcag accgtcgtgc cgttatcgaa ggtctcaaat caggtgtcat cacagttatt
     2281 gcgactgacc acgcgcctca tcatgtagat gaaaaaaatg ttgaagatat taccaaagcg
     2341 ccatctggta tgactggctt agaaacatcc ctgtctctcg gcttgaccta tttagtagaa
     2401 gctggtgagt tgagcttgat ggaattactt gaaaaaatga catacaaccc agccaagctt
     2461 tacaactttg aagcaggtta cttggctgag aatggtccag cagatatcac tatttttgat
     2521 gccaaggctg accgccttgt ggactcccat tttgcttcca aagcagctaa ttcaccattc
     2581 atcggtgaaa ccttaaaagg gcaggttaaa tataccatct gtaagggaca aatcgtctat
     2641 caagcttgat aggagttaga atatgaatta ttttcgaaaa cgtagggaga gacaagcgaa
     2701 atctaatagt ggaatttact gtcccgcagc taatcgttcc aaaattcaat atgaaactaa
     2761 agaaaaagct gaccatgcgg ttcaatatga taacggaggt ttagttagaa gctattattg
     2821 tcgtacatgt gcgtgttggc atactacttc aaaatctaat aaacctccgc taagtttgaa
     2881 aaactatggt ctgaaactct ttggtttaga taaatcagaa tagaaagaga agtatgtata
     2941 agacaaagtg tttacgagag aagttagtat tatttttaaa aattttcttc ccaatcctga
     3001 tctaccaatt tgccaattat tctgcctctt ttgttgatac tgcaatgaca ggtcaataca
     3061 acactatgga cttggctggt gtatctatgg caaccagtat ctggaatcct ttctttacat
     3121 ttctaacagg gattgtgtca gccttggtgc ctatcattgg tcaccatctt ggtcgaggca
     3181 aaaaggaaga agttgcgtct gatttttacc aatttattta tttggccttg ggcctatctg
     3241 tggtcttgct ggggatggta cttttcttgg caccaacaat cttgaatcat attgggttag
     3301 aagcagcagt agcggcagta gcggttcgct atctttggtt tttatctatc gggattatcc
     3361 ccttgttgct ctttagcgtc attcgttcct tgctggattc gctgggcttg accaaactgt
     3421 ccatgtacct catgcttttg ttactccctc tcaatagcgg atttaactat ctcttgattt
     3481 acggtgcctt tggtgttcca gaactgggag gggctggtgc tggtttagga acatccttgg
     3541 cctactgggt cttgcttggg atttctgttc tggttttatt taaacaggag aagctcaaag
     3601 ccttacacct tgagaaacga attccactta atatggataa aattaaggaa ggagttcgtt
     3661 taggtctgcc tattggggga actgtcttcg cggaagtggc tgtcttttca gtggttggct
     3721 tgattatggc taagttttcg tccttgatta tagctagtca ccagtcagct atgaactttt
     3781 caagtcttat gtacgccttt cctatgagta tctcatcggc tatggctatt gtcgtttcct
     3841 atgaagtggg agccaagcga tttgatgatg cgaaaaccta tattggtcta ggaagatgga
     3901 ctgccctcat ttttgcggcc ttcaccttaa ccttccttta catttttagg ggaaatgtgg
     3961 ccagtcttta tggtaacgac ccaaaattta tcgatttgac agcgcgtttt ttaacttata
     4021 gtcttttctt ccagttagca gatacctttg cggcgccgct tcagggaatt ttgcgggggt
     4081 ataaggatac agttattcct ttttaccttg gtttgcttgg ttattggggc gtagcaatcc
     4141 ctgtggctac gctatttgat tccctaacag attttggagc ttattcttac tggatcggct
     4201 tgattattag tttgattgtg agtggggcgc tctaccgttg gcgtttaact gtgattatga
     4261 agagatttga atctttagca aaatccaaac gctaaaaagt ttgtgaaaaa atatccttga
     4321 caagaaaatc ccttgttttc acggggtttt cttttttatt ttgtgaaatt tcttttagaa
     4381 aaactttgac agtatttgcc aaaagcggta aaatagtaag gtaagaagaa agttagaaag
     4441 gcaagaagat gtcaacttta gataaaaatc ttttgctaga aatgttccgt aagatggaag
     4501 aaatccgtcg catggactta aaaattgcac aattagtaaa gaaagggaaa gtgccaggaa
     4561 tgacgcactt ttctgttggt gaagaggcag ctaacgtggg ggctatgtta gctctcaatc
     4621 cagatgatct gattacctca aaccaccgtg gacacgggca agctattgct aaagggattg
     4681 acctcaacgg aatgatggct gaaatccttg gtaaatacac tggaacctgt aaagggaaag
     4741 gtggatctat gcatatcgct gaccttgatg ctgggaacct tggtgccaat ggtatcgtag
     4801 gtggtggtat ggggatcgct gtcggtgcag ccctcagtca gcaaatgcaa aataccggta
     4861 aaatcgttgt ctgcttcttt ggagatggtg cgaccaatga aggtgttttc cacgaagcag
     4921 tgaacatggc ttctatctgg aacctgccag tcattttcta ttgcattaac aacggttacg
     4981 gtatctctgc ggatatcaag aaaatgacca atatagaaca tatccatcaa cgtagcgccg
     5041 cttatggaat tcctggaatg ttcatcgaag acggtaacaa tgtcatcgat gtctatgaag
     5101 gatttcagaa agctgtagac catgttcgca gtggcaatgg tccagtcttg attgaaagtg
     5161 taacttatcg ctggctcggt cactcatcat ctgaccctgg taaatatcgt acgcgtgaag
     5221 aagtggaatt gtggaaacaa aaagatccaa tcgaaaacct ccgcaattac cttattgaaa
     5281 ataacattgc aagtgccgaa gaattggaag aaatccaagc gcaagtaaag gaagcagtag
     5341 aagcttctgt taaatttgca gaggaaagcc cattcccacc gcttgaatca gcctttgaag
     5401 atatttacgc agactaagga gaaagagata aaatggaaac aaaaacaatg tccttccgtg
     5461 acaccattat ccttgctatg tctgaggaaa tgcgtcgcga tgaaaatgtg ttcttgatgg
     5521 gagaagacgt cggtgtcttc ggaggagact tcggtacttc tgttggaatg cttgaagaat
     5581 ttggtccaga acgtgtccgt gactgtccga tttctgaagc tgccatctct ggagctgcag
     5641 caggagcagc catgacagga cttcgtccaa tcgtcgatat gaccttcatg gacttctctg
     5701 ttattgccat ggacaatatc gtcaaccaag ctgctaaaac acgttacatg tttggtggta
     5761 aaggtcaggt tccaatgact gttcgttgtg cagctggtaa cggagttggc tctgccgccc
     5821 agcactcaca atctctagag tcttggttta ctcacattcc aggacttaag gttgtggtac
     5881 ctggaacacc tgcggacatg aaaggcctgc ttaagtcttc tatccgtgat aacaacccag
     5941 ttattatact tgagtacaag tcagaattta accaaaaagg ggaagtgcca gttgatccag
     6001 actacacaat tccacttggg gttggtgaaa tcaaacgcca aggaacggat gtaacagttg
     6061 ttacttatgg aaaaatgctt cgccgtgtgg ttcaagctgc tgaagaatta gcagaagaag
     6121 gaatttcagt tgaaattgtt gacccacgta cccttgttcc gcttgataag gatatcatca
     6181 taaactcagt gaagaagact ggtaaggtta ttctggtcaa cgatgcccac aaaacaagtg
     6241 gctatatcgg tgaaatttca gctattattt cagaatcaga agcatttgac tatctagatg
     6301 caccaatacg ccgttgtgca ggagaagatg tgccgatgcc ttatgcacaa aacctagaaa
     6361 atgcaatgat tccaacagtt gaaagtatca aagatgcaat ccgaaaaact tataacaaag
     6421 actagggtta cataatataa gttatgtaaa taaaataaag ctgacgagaa actttgtatc
     6481 ttttaggtgc agagctcttc gtcattaata tcttagatta gagcacgggc taaaagatcg
     6541 gaaaaaagat aaatctcctt ggcttcatcg aagccatcgt cgatttccta tttttcagtc
     6601 gcttttgacg ccctttgtat cataaataga attggagagg tcatggctga tgacaagcta
     6661 agagcgactc ctgcagctag aaagttagcg gatgatttag ggataaacct ctacgacgtt
     6721 tctggctcag gtgcaaacgg tcgtgtccac aaagaagacg tggaaactta taaagacaca
     6781 aacgtggttc gcatttcgcc acttgcaaaa cgaattgccc tcgaacataa cattgcttgg
     6841 caggaaatcc aaggaaccgg tcatcgtggt aaaatcatga agaaggatgt tttggccctg
     6901 cttcctgaaa atatcgaaaa cgatagcatc aaatctcctg ctcagattga aaaagtggaa
     6961 gaagtccctg ataacgtaac accatatggt aaaatcgagc gtattccaat gacaccaatg
     7021 cgtaaggtta ttgcccaacg catggttgaa tcttacttga ctgcgccaac cttcaccctc
     7081 aactatgaag ttgatatgac tgaaatgttg gctcttcgta agaaggttct tgagccaatc
     7141 atggaagcaa ctgggaagaa gactactgta acagaccttc tttcgcttgc agttgttaag
     7201 actcttatga aacacccata catcaatgct tcattgacag aagatggcaa gactattatc
     7261 actcacaact atgtcaatct tgccatggca gttgggatgg ataatggatt gatgacacct
     7321 gttgtttaca atgctgagaa gatgagtctt tcagaactgg ttgtagcctt taaggatgtt
     7381 attggccgta ccttggatgg taaattggct ccaagtgagt tacaaaattc aacattcaca
     7441 atcagtaatt tgggaatgtt tggtgttcag tcctttgacc cgattattaa ccaacccaac
     7501 tcagctatcc ttggtgtcag ttcgacaatc gagaagccag ttgtcgtcaa tggtgaaatt
     7561 gtgattcgcc caatcatgag tttaggatta accattgacc accgtgtcgt agatggtatg
     7621 gctggtgcta agtttatgaa ggacttgaaa gagttgattg aaaccccaat ctcaatgttg
     7681 atttaagagc aagagtattc atttttaaga tatagataaa ggaaggaaga catggcctta
     7741 gaagtaatta tgccaaaagc cggcgtggat atgacagaag gacaaatcgt ccaatggaat
     7801 aaaaaagtcg gagaatttgt aaaagaagga gaaatccttt tggaaatcat gactgataaa
     7861 gtcagcatgg aattggaagc cgaagaagat gggtacttga ttgccattct caaaggagat
     7921 ggtgaaactg tccctgtaac ggaagttatc ggttaccttg gtgaagaaag ggaaaacatc
     7981 ccaacagctg gagcagcatc gccagaagct agccctgtac ctgtagcaag tacctcaaac
     8041 gatgatggta agagcgatga tgcttttgat atcgttgtga ttggtggagg tcctgctggt
     8101 tatgttgcag ccattaaagc tgcccaactc ggcggtaagg ttgcccttgt tgagaaatct
     8161 gaacttggtg gaacctgctt aaaccgtgga tgtattccaa ccaagaccta ccttcataac
     8221 gctgaaatta ttgaaaatat cggtcatgct gcaaatcgtg gtatcgtgat tgaaaatcct
     8281 aacttcactg ttgatatgga aaaactttta gaaactaaat ctaaagttgt taatactctt
     8341 gttggtggtg ttgcaggact tcttcgtagc tacggagtta ctgttcataa aggaattggt
     8401 acaatcacta aagacaagaa cgtcttggta aatggttctg aattgcttga aaccaagaaa
     8461 atcattcttg ctggtggttc aaaagtcagc aagatcaacg tccctggtat ggaatctcca
     8521 cttgtcatga ctagtgatga cattcttgaa atgaacgaag tgccagaaag ccttgttatc
     8581 atcggtggtg gagttgtcgg tatcgaactc ggtcaggcct tcatgacatt tggttcaaaa
     8641 gtgactgtta tcgaaatgat ggaccgtata gttccagcta tggatgcgga agtttctaag
     8701 aaccttcgct tgatccttga gcgtaaagga atgaccatct tgactggtac taaactgcaa
     8761 gaaatcattg aggaaaatgg tcaacttcgt atcaaggttg aaggaaaaga cgatatcatc
     8821 gcaagcaaag ctcttctttc aattggtcgt atgccagacc ttgaaggtat tggagaggtt
     8881 gagtttgaat tggatcgtgg ttgtatcaag gtcaacgaat acatggaaac ttcagttcca
     8941 ggcatttatg caccaggtga catcaacggt actaagatgt tggctcacgc agctttccgc
     9001 atgggtgaag tttccgctga aaatgccctt aaaggaaatc atgcagttgc caaattgaat
     9061 ttgactcctg cagccatcta cactctccct gaagtagcag cagtaggttt gacagaagaa
     9121 caagcccgtg agaaatacga tgttgccatc ggtaagttta actttgctgc taacggtcgt
     9181 gctattgcat ctgacgcagc tcaaggtttc gtaaaagtta tcgctgataa gaaatacgga
     9241 gaaatccttg gtgtacacat tattggtcct gcagccgcag aattaataaa cgaagcatca
     9301 agcatcatcg aaatggaaat cactgttgag gaaatgctga agaccatcca cgggcaccca
     9361 acttactctg aagtgatgta cgaagcgttt gcagatgttc taggaatggc catccattca
     9421 cctaagaaaa aataaaacga agatagatta gactggaagg ttatttccag tttctatcat
     9481 ataaagtaaa gggatatcat gaaatacatt atcaatcatt caaatgacac tgcttttaat
     9541 attgccttgg aagaatacgc ctttaaacac cttttggatg aggatcaaat cttcctactt
     9601 tggattaaca agccatctat cattgttggt cgtcaccaga acactatcga agaaatcaac
     9661 cgtgattatg ttcgcgaaaa tggtattgag gtagttcgcc gtattagtgg tggtggagct
     9721 gtttaccacg atttaaataa cctcaattac acgattatct ccaaagaaga tgaaaataag
     9781 gcatttgact tcaagagctt ctcaactccg gttatcaata ccctggctca acttggggtt
     9841 aaagctgagt tcacaggtcg taatgacctt gagattgatg gtaagaagtt ctgtggcaat
     9901 gcccaagcct atatcaacgg ccgtatcatg caccacggtt gcttgctctt tgacgttgat
     9961 ttgtcagtcc tcgcaaatgc ccttaaggtt tcaaaagata aatttgaatc aaaaggtgtg
    10021 aaatccgtcc gtgcccgtgt aaccaatatt atcaatgaat taccaaaaaa aatcacagtc
    10081 gaaaaattcc gtgatttact cttggaatac atgaaaaaag agtacccaga gatgactgaa
    10141 tacgtctttt cagaagaaga attggccgaa atcaatcaca tcaaggatac taagtttgga
    10201 acttgggact ggaactatgg taaatcacct gaatttaacg tccgtcgtgg aaccaaattc
    10261 actagtggta aggttgaagt ctttgctaac attactgaat caaaaatcca agacatcaag
    10321 atttatggtg acttctttgg tattgaagac gttgctgcag tagaagatgt ccttcgtggg
    10381 gtgaaatacg aacgcgaaga tgttcttaag gcgctaaaaa ccattgatat cacacgctac
    10441 ttcgctggta ttagccgtga agaaatcgct gaagcggtag ttggataaat caaaaaaaga
    10501 agttggccaa ctaaccaact tctttttttg atatttattt acataattta aaatacgtaa
    10561 aatcataaac tatccagagc attcttttgt tcatcattaa caatatgggt atagaggtca
    10621 gtgacttgtg tgctggcatg tcctagttgg tgactgacta aaacttgtga tttagtcgca
    10681 tcatagagcc tagttgctag tgtatggcgc agtttatggg gtgttacacg tactttaaaa
    10741 tcctctgagt atttagcaac cattttctca acgctagaag catcgatacg attaggaaca
    10801 cctctgtaga gagttaaaaa aagggctgta tctgtttttt ccgttttata gcgttgattc
    10861 cgaatggcca gataattctc taaataaggt ttagcaaaag cagcgacatt gactgagtca
    10921 cgtttgccac cttttcgagt aacatcaata accatcattt ttagattgag atctcttaga
    10981 tctagattaa cagcttcaga taagcgaaca ccagatgcca agagaagggc aataatggct
    11041 aaatctcgtt ctttattttt gttgaatgat gagagagctc gatttgaaag ctgttgtggg
    11101 tgctcttgat cgatataagt tagaaaacct tctgtttcat cacctagaaa gagtttttgc
    11161 ttgatatttt cagctctggc agcaagggtt tctttctttt tcttggttga aacttttttc
    11221 attacattac gatagaaata aggttccccc tgatcgtttt caacctcctc ggttagatac
    11281 ttgtaaagac tagaaagtgc tgataaggtt cgattgatag ttgtctgtga aacaccttgt
    11341 tttgttgtat tagcattcag caagggacgt tcacgtagat aaaggataaa ggattccatg
    11401 tctttcttag acatattttc caaaactgat aaaggaatat cggatatttt atcagcgttt
    11461 gaaataccag actccaaaac ccagctgaaa aatcggtcat attccttaag gtattcgtac
    11521 agggttgtaa aactgtaggg cacagccagc ttagattggt agtattccag aacataccag
    11581 ggcatgagtt gttttagttt gtcgattcgt tccagtaaaa tctcacgttt catgtatttt
    11641 ctccataagt aagtatacta gtagtatagc atagacttgt atatttttca agaaaattat
    11701 agtttttcgg aaagatgtta taggagtttt tcaaagtgat aaaaagactt agacctacaa
    11761 acaaaacaga ataaggaaaa taataaaaat ctcacccact aaacttctgt taatactaca
    11821 taactgaaga gctatataag aagctatgag atacaaaaca cattgtataa tagattgaaa
    11881 ctagaatagt acatctggac ttctaaaaca ttgctagaaa ttgatttgat tgtcctgatt
    11941 gttttatcct atttctattt catttctcta tataattgct attgttttct ttttcatgat
    12001 tttaatctta ctgtacagat ttgatacagt aaactccttt ctagctttat actttatca
//
LOCUS       DAVLTT010000055        11978 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLTT010000055 DAVLTT010000000
VERSION     DAVLTT010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11978
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.055"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            413..574
                     /locus_tag="VYN15_001671"
     CDS             413..574
                     /locus_tag="VYN15_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452963.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            666..2345
                     /locus_tag="VYN15_001672"
     CDS             666..2345
                     /locus_tag="VYN15_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1452964.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRSQKAMEGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCTKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            2613..3179
                     /locus_tag="VYN15_001673"
     CDS             2613..3179
                     /locus_tag="VYN15_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452965.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            3501..3689
                     /locus_tag="VYN15_001674"
     CDS             3501..3689
                     /locus_tag="VYN15_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1452966.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            3751..4509
                     /locus_tag="VYN15_001675"
     CDS             3751..4509
                     /locus_tag="VYN15_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1452967.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYPGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVSDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            4567..5421
                     /locus_tag="VYN15_001676"
     CDS             4567..5421
                     /locus_tag="VYN15_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1452968.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            5533..6417
                     /locus_tag="VYN15_001677"
     CDS             5533..6417
                     /locus_tag="VYN15_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV1452969.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            6580..7284
                     /locus_tag="VYN15_001678"
     CDS             6580..7284
                     /locus_tag="VYN15_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV1452970.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMNYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDSVAWVRQGIF"
     gene            7434..7715
                     /locus_tag="VYN15_001679"
     CDS             7434..7715
                     /locus_tag="VYN15_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452971.1"
                     /translation="MWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            8160..8636
                     /locus_tag="VYN15_001680"
     CDS             8160..8636
                     /locus_tag="VYN15_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1452972.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            8636..9412
                     /locus_tag="VYN15_001681"
     CDS             8636..9412
                     /locus_tag="VYN15_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV1452973.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSSVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLRVVEERHKELEGKNSYGI"
     gene            9402..11159
                     /locus_tag="VYN15_001682"
     CDS             9402..11159
                     /locus_tag="VYN15_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1452974.1"
                     /translation="MEFKKLVIENFRNFSSIEVALSNKNVIFGMNDSGKTNLLFAIRY
                     LLDRTIRNKGFIKSDYHRHDTSRPIKIQLELDLSDRKMEGDEESLKSSHSRLLISTVA
                     GARNNSSLDTFFISLEAVYNEKELFGNPVLSWGSTLDNLVEVPQYGTRSDIDKIFQIV
                     YVNPAIELDSFFKRNRRILFSDDSKTDEDVKLEEEIENNIEKLNENISNLHLITSVQS
                     QLTEAYKSYRKENLEIKIQSEISISGYLDNLTPYINWNDDTHNYPTSGDGRKKLLSYA
                     INHLISEKQYNKKVIIYLIEEPENSLHRSVQISLSKQLFVQNIYEYFFLTTHSAEVLY
                     EMDNTQLIKITNQQDATGQSVYYTVPNEFSNLKKKLNKSLAQSIFYDRILLVEGPSEY
                     YLFSAIFEYVSPNFEADGKYLLQVDGINFKPYSELYKALGIDFWIKTDNDLKASRGDK
                     HVFSPIGLNRCIDLLDHSATPILDNYRIDFSSKDERKQNIKSKKEELYLTNHNLVLQL
                     NADGIFISEIDLENDLAQVLSDSERNEMSKLDFVNWLQSSKQYNMLEYISNHLTKEIA
                     LKIVESGYFKVLAEFLDYE"
     gene            11152..>11978
                     /locus_tag="VYN15_001683"
     CDS             11152..>11978
                     /locus_tag="VYN15_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HEV1452975.1"
                     /translation="MSDIATQDKNVKKELLEYQGNILILANAGSGKTTFLTKKLKSDS
                     KRLNNYQKLAAITFTRNATEEIKQKLVDIPDNVVVSTIDSFLDKEIILPFLNQKYEIQ
                     TSVQFSFRIDHNFSDYSTGIKQILQDGIFGTYDFPTSKHGKNFKCEVALDILKTIDSA
                     SEYIKYKFNTLYIDEFQDCDQSMNDLFLYLKNELGIPLFIVGDDKQSIYQWRGASPKY
                     INNLWKNKNDFRKKRFIGNFRSLPRIVDFSLALTPEVTVDNIREEGSILYLEPNQDYP
                     "
BASE COUNT         4320 a         1613 c         2394 g         3651 t
ORIGIN      
        1 tatagaattt tgttacatca agataaatat tttctgatgg tcaaatttta aaaagattaa
       61 taactctcga taaattttga accttaacaa ttgaatagac caagacaaga cgttaattat
      121 ttttggagcg taataaccta tccgtcaaga tctttcggct gaataattcg gcaaaaaaag
      181 ttctgctaag caaaaagaaa gtgagcgata agtaagagtt tgaatatagg gagggatacc
      241 ctatccgcta tgaagaaaat gaggataatg atacttctaa ggttgaagcc ggctcatccg
      301 gaatagaggc ggaggtgaga ttcctatgtt gctaatccaa agcacttgtc aatgtcaaaa
      361 aacttaatta aacaaataat tattagatat aaaactttag aggaggtata tattggacaa
      421 tgactggaat ggattggctg atttaatagc aaatctgatt gcaaaatatg ctggtgcttt
      481 agatttagat aatctacccg atccaacgcc agcaaaaaat caagagatga aaaatagttt
      541 tgacatggca aaaacacaaa ttgagacgga ctaataaaag tgttataata tacttgaaat
      601 gatagtccaa acttaaatta aaaaaattat atatgatata gaaaaattat attgaggtta
      661 atactatgtc aaaagaaaaa ataaaagtat acctctatac acgagtatct acgtcaatac
      721 agatagaggg gtattcgtta gaggcacaaa aatcacgaat gaaagctttt gctatttaca
      781 acgattatga aattgttgga gagtatgaag atgccgggaa gtctggcaag tctattgaag
      841 gtagaataca gttcaatcga atgatggaag atataaaatc tggaaaagat ggagtatctt
      901 ttgttcttgt gtttaagtta tcaagatttg caagaaatgc cgctgatgtt ctttctacac
      961 ttcagataat gcaggattat ggagttaatc ttatctgcgt tgaagatggc attgattcat
     1021 ctaaagatgc tgggaaacta atgatttctg ttttatcagc tgtggctgaa atagaaagag
     1081 aaaacatccg tattcaaaca atggaaggtc gcagtcaaaa agcaatggaa ggaaaatgga
     1141 atggtggttt tgctccgtat ggatataaac ttgaagacgg caagctgttt ataaatgagg
     1201 aagaggcagt tgcaataaga acgattttcg accagtatgt aaatactacg ataggagcca
     1261 atgggatatc taaatactta gagaatcatg gaattagaaa aatcccaaga cagaatggta
     1321 agaatccttt gtttgatgca ggtcttataa gaaagatatt aaagaatcct gtatataatg
     1381 ggaaaatagc atttggaaga agaactttag aaaaagttca tggtacaaga aatgaatata
     1441 agcaggttga acaagatgaa tatctaatat ctgaagggat acatgaagct atagtttccg
     1501 atgaagtttg gcaagctgct caggttaagc taaaatctca agcaaagaaa tatgagcatg
     1561 tgaataaagg aaaagataca cgcacacact tgctttctgg aattgtaaaa tgcccgatat
     1621 gtggagtggg aatgtttggg aacaagtgta ccaagaaaaa gaaagatggc acaaagtata
     1681 aagattttta ttactatggt tgtaaacata ggcagatgat aagaggtcat aagtgtacat
     1741 tcagtaagca aattagagaa gaattgttag atgatgctgt tgcagaggtg attgtcaaga
     1801 tagtaagtaa tccgaaattt gcttctatga tgcaagaaaa aatcaacatg aaggtggata
     1861 cctctgaaat agaaaaagaa atagataatt accaaaagga attgagaaag agtcattcta
     1921 caaagtttaa gctaattgag gaaatagata atttagatgt tgaagataag cactataaga
     1981 gaaggaaaca ggatttagat gatagactat atcgtatgta tgacaaaata gatgaattag
     2041 aatcatcact aattgatgcg aaagcaaaga aacagactat tgaagctgaa aaacttacag
     2101 gagataacat atataaggtt ctgatctatt ttgataagct ctataaagtc atgaatgatg
     2161 tagagcgtag gcagttaatt tcagctttga tttctgaaat tcaagtttat gaagaaaaac
     2221 aatctaacgg acaatggcta aaatccatta cttttaagct accaattata gaagaaaatc
     2281 tcaacataga tttggacaat gatgaacaag ttgaatgtgt aagtttatta gagaaacgta
     2341 gttaatcctc aaaaggttcc ccaaactttt tgagtcccac tgacgcatca cgctgaggcg
     2401 gtatcactgc ttgtacgagt tgaagcatca gcgaagtaaa agtagatgtt cagccaatgc
     2461 gacgaggtga gaccgaaggt cgataaggtg tgttctgggt ataggactcg taaagtaagt
     2521 aggaaatatg atgagatgat acagagagcc tgaattggtc aggtgacgtg cttatgtaca
     2581 ttagcctgat aatgaaaatg gagagattat cgatggttat attggaattg taccaaaatg
     2641 attattctaa agatttagta gcatttgatt ccatagaaga tgggaaagcc tttgtagctc
     2701 aaatcccggg atacactctg gaaacagaag atggttttga agtggagtat tttaatccta
     2761 aaaacatacc ggattatatg gaaattattt ttaacggaaa tattgttcct ttatctaaat
     2821 ttatgttcga tcctgaggaa aatgtaaaca ttatttggaa agagatttca aatttatccc
     2881 tcaaaaatga tagagtgatc gaaggatatt caaaaattga tgcatatgtc gttaacaacc
     2941 atgaagttaa agcctatgtc gaaacaagag aaacgaacta tcgtaaagca aaagacttct
     3001 tagaaagccg cggatatgaa atcgacagaa gctttttcgg aagtgaagac ggtgaagcga
     3061 ttctttacag aaaaaaaggg atcgaagttt ggcatttctt gtgtcactta gacccaatgt
     3121 ttgtagagat tgaagatgta gaaggatatg ttaaagaaga agttggagag attcaatagt
     3181 caaccaaagt tccttgtgag tatatacctt tgctagtaaa agagtcaaaa cgttataacg
     3241 aaggggggta agaaaaccct tgagtgtaag tctttttctt gtttagaggg aaagtattag
     3301 agtagccgct cataatttat actagatttg ataactgatt tgagacagat tttatttcta
     3361 taaatattgt gaaaattttt taataccaaa gatttaaagt tactgtgtaa aaaatcctct
     3421 ccacttttaa actaatgtat tataaaagcc agttgacaca agtgttacac ctgtgataga
     3481 attaacttga ggtgatgaaa atggcaaccg ataaaaatag aataatgatt agcttggatg
     3541 ataaaaatct agagaaactt gaaaatttag tagaagatgc tagagataga aggggaatgc
     3601 gactaacaaa gtcccaggtt attgaattac tcctaaatac cgttgattat ttcgatgata
     3661 ttatgggggc tatttactca aaaaaataag agcaaaattg ctattatttt ttacaaattg
     3721 gtgtaacact agtgatatag gagtgatgaa atggttgttt atattagaca aagtaaatta
     3781 ccaagtgagg tttcaattaa taaatacaat gctcaagtag gtgcctactt acaaggagaa
     3841 gaagttattt tatatcaatc tttttctgaa ataaaagagt taacaagtga agatatagtt
     3901 gtagattata taatggagac tagagcatta ctaaaaatga tgggcttaaa cgttccggtt
     3961 catgactatc ctattgagct taaagagttt tatggtcgaa agatttatcc tggtatttta
     4021 ggagagattg tgaatatacc tgataattgg ggaaaattta ttaagcctaa agctggttca
     4081 aaagtcttta ctggaagagt tgttaatgga acccatgatt taataggtat tggtctacct
     4141 ttcgactatc ctatatggat tagtgaggtt gtagaattca tagctgaatg gcgttgtttt
     4201 gtgttagatg gtcgcgtatt agatgttcga ccctatacag gtgattatca tgcacaattt
     4261 gatgcaagtg taagtgatga agcgatatca tgttggaaag atgcgccaat agcttatgga
     4321 ctagatatcg gtgttactcg cgatggcaga acacttgttg ttgaagtaaa tgatggttat
     4381 gcattgggaa attatggcct atctccttta aaatcaatca attttcatag agctaggtgg
     4441 aaagaaatgg taaaacccta ttttgaaaaa aatgaaattt ttaaaatcca acaggatgtt
     4501 attttctaaa ataaatatgg tagataacca atataaaaag catcaaaatg aacaaggagg
     4561 aatctgatgc ttggagcaat tattggagat attgtcggtt ctgtttacga atggaacaat
     4621 atcaaaacaa aggactttcc tttatttcgg aaggactgct tttttacaga tgacacggtt
     4681 atgacctgtg ctgttgcaga agcaattatg aatggtggac aaaaagacga cttcattgac
     4741 gcgatgaaga aatatggcag aatgtatccg aatgctgatt acggtgctcg gtttaatgca
     4801 tggctaaaca gcgataaccg tgagccttat aatagctttg ggaatggatc agctatgcgt
     4861 atttctccat gtgcttggat catggactgt ggtttttatg cgaaaactgg tatatggcca
     4921 tcatctagag gacttacgag tctttctgca gaggtaactc ataatcatcc agaaggtgtc
     4981 aaaggcgcta tggctacagc tgatgctatc tttctatgtc gtttttactt tggtggttat
     5041 tgtagagagt acgagcaatc aattaacgac aatcctacag agtgtaaaag acgaattaag
     5101 gattatatag aaaaagaata cgattacaat ctatctcaaa ctttagatga aatccgtcct
     5161 aactatcgtt ttaacgaaac atgtcaggaa actgtccctc aagccattat cgcctttctt
     5221 gaaagtagag acttcgaaga tgcgataaga aatgccatct cacttggtgg cgacagtgat
     5281 actctcgcag caatcacttg tagcatagca gaggcagctt acggtattcc tgattggatc
     5341 aaggataagg cctattctta cttggatgaa cccttaaagg atgtagttag gcgatgggaa
     5401 aatagaataa aagcgtatta atctccagta cgtcagattt ctcttttctg tattttcatt
     5461 gtataatagg attacattta cttgcatacg acgaaatgta aacatttctg tttaaaatta
     5521 aggataaaat caatgaaaaa agcaatggta attatcaacc ctacttctgg tggcgagaag
     5581 gctttggatt acaaagaaaa gctggaaaat aaagcaaaag aatactttga atatgttgaa
     5641 accaaaatta ccgaaaaagc gctggatgca acacattttg ctgaagaagc ttctcgtgag
     5701 cagtatgatg cagtggttgt gtttggtgga gatgggactg tcaatgaagt catttcaggt
     5761 attgatgaga gagactacat tcctaagtta gggattatcc caggcggtac gggtaacctc
     5821 attacaaaac ttttggaaat caatcaagac atcgatggcg caattgacga actggatttt
     5881 gatttaacca ataagattga tatcggtaaa gcaaatgaca actattttgg ttatatcttt
     5941 agtatcggtt ctctgcctga ggcgattcac aatgttgaaa tagaggacaa aacaaaattc
     6001 ggtattttaa cctatgctgt aaataccatg aagtctgtca tgacagatca ggtctttaac
     6061 attaaggttg agacagaaaa tggaaattat gttggtgaag ctagccatgt tttggtcctt
     6121 ttgacaaatt acttcgctga taagaaaatc tttgaagaaa acaaggacgg ctatgccaac
     6181 attttgattc tgaaagatgc ctctatattc tccaaattat ccgtcattcc tgatttatta
     6241 aaaggggatg ttgtcgcaaa tgataatatc gagtatatca aagcgcgtaa tattaaaatc
     6301 tcttcagata gtgaattgga gtcagatgtt gacggagata aatcagataa cctacctgta
     6361 gaaatcaaag tcctagctca gcgagtagaa gtattttcaa aaccgaaaga ggattagtat
     6421 atagagaaag ccttttttaa ggctttttgt atactttaaa agatagttcc tttaacaacg
     6481 gacattcctt gcaaatagtt tacaaaaata gtatactgga tttattgagt ttgaaaacgt
     6541 ttgcgtaaaa tttggatgaa tactttagga gacaaattga tggaattgag tgctatttac
     6601 cataggcctg agtcggagta tgcctatctt tataaggata agaaactcca tattcgaatt
     6661 cgaactaaga aaggggacat tgaaagcatc aacttgcact atggggaccc ttttatcttt
     6721 atggaggagt tttatcagga tacaaaagaa atggtcaaga taacttctgg taccttattt
     6781 gaccattggc aggttgaagt gtcagttgac tttgcacgta tccagtatct ctttgagctc
     6841 agagatacag aaggtcaaaa tattttgtat ggcgataaag ggtgtgtgga aaattctcta
     6901 gaaaatcttc atgcaattgg gaatggattt aagttgcctt atcttcatga gattgatgcc
     6961 tgcaaagttc ctgactgggt ttcaaatacg gtatggtatc agatatttcc tgaaagattt
     7021 gccaatggca atgctctatt aaaccctgaa gggactttag actgggattc atctgtcaca
     7081 cctaagagcg atgatttctt tggtggtgat ttacagggga ttattgatca tatgaattac
     7141 ttgcaagact tgggtattac tggactatat ctttgtccca tctttgaatc tacaagcaat
     7201 cacaagtaca atacgacaga ttactttgaa attgaccgtc attttggaga cagtgttgca
     7261 tgggtgcggc aagggatttt ttagaactaa ttaatcacaa agggctacct ctttttaatc
     7321 cgcttgtagg tgattctcat gtaaataata gacaagaata tgacaataca gggagtggaa
     7381 atttataacc tgaaaagtgg aatgaaactg caaagcagct ttataatgct ataatgtggt
     7441 tgattatttt atggaatgct aagccggata cacctttatt taattttaaa gacgaagtaa
     7501 ttaagtataa aacatatgag ccttttgaaa gcagtataaa aagagtaaat actactataa
     7561 agaatggtag taaagggaaa actctgactg agatgattaa tggctacaga gcggataacg
     7621 atattagaga tgaaatttgt aactttaata ttctgaaaaa taaaattcgt gatatgaaag
     7681 accaacaagg aaatacaatg gaatcttact tttagttatt gttgaatttt gggtattcta
     7741 taaaatatcc taattgagat ttaaatagta gactatacaa tatagttaaa atatcagtaa
     7801 aaacaacact ttattgaggt attggatacg ctttgctaat agcctaataa tcacatgtgg
     7861 agtgttgcta caacgaaaaa ggtgataatc cttgatttca agctatttta taagcatttt
     7921 gtctttgtag ataaaggcaa ttttgacaat aaaaatccta aaaggtgaat cgttatagat
     7981 gtatttgtag atatcgtttg cgcatcgaaa aaattaatac aagaataaat atttatggct
     8041 ctttaggtga cttttataga agtaaagttt aggatagaaa aacaagaaat aacgcaccat
     8101 ttttggtgcg ttatgctttt ttatgctata atggatttat aaaaataaag gagtttgcta
     8161 tgattggaaa gaacataaaa tccttacgta aaacacatga cttaacacaa cccgaatttg
     8221 cacgaattat aggaatttct cgaaatagct tgagtcgtta tgaaaatgga actagttcag
     8281 tctctacgga attaattgac atcatttgtc agaagtttaa tgtatcttat gtcgatattg
     8341 taggagaaga taaaatgctc aatcctgttg aagattatga attgactttg aaaattgaaa
     8401 ttgtgaaaga aagaggtgct aatctattat ctcgactcta tcgctatcaa gatagtcagg
     8461 gaattagcat tgatgatgaa tctaatcctt ggattttaat gagtgatgat ctttctgatt
     8521 tgattcatac gaatatctat ttagtagaaa cttttgatga aatagagaga tatagtggct
     8581 atttggatgg aattgaacgt atgttagaga tatctgaaaa gcggatggta gcttaatgga
     8641 aatccaagat tatactgata gtgaattcaa acatgcttta gcaaggaatc ttcgttcact
     8701 gacaagagga aaaaagtcca gtaagcaacc tatagcgatt ttgcttggag gtcaaagtgg
     8761 tgccggtaag actacaattc atcgtattaa acagaaagaa tttcaaggaa atattgttat
     8821 catagatggt gatagttttc gttctcagca tccacactat ttagaactgc agcaagaata
     8881 tggcaaagac agtgtagaat ataccaaaga ttttgcagga aaaatggtag agtctttagt
     8941 aacaaaattg agtagtttga gatacaatct tttgatagag ggaactttac gaacagttga
     9001 tgttccaaag aaaacagcac aactcttgaa aaataaggga tatgaagtac aattggcctt
     9061 aattgcgaca aagcctgaat tgtcgtatct aagtactctt atccgttatg aagaactgta
     9121 cattatcaat ccaaatcaag cacgcgcaac tccaaaagaa catcatgatt tcattgtaaa
     9181 tcatctagtt gataatacac gacaattgga agaactggct atctttgaaa gaattcaaat
     9241 ttaccaacga gatagaagtt ctgtatatga ttcaaaagaa aatacaactt cagcagcaga
     9301 tgttcttcaa gagttactct ttggggagtg gagtcaggta gagaaagaga tgttgagggt
     9361 ggtggaagaa agacataaag agttagaagg aaaaaatagt tatggaattt aaaaaactag
     9421 taattgaaaa ttttcgtaat tttagttcta ttgaggttgc tttatcaaat aaaaatgtta
     9481 tatttggaat gaatgattca gggaaaacaa accttctatt tgcaataaga tacctcttgg
     9541 acagaactat acgaaataaa ggttttatta aatcggatta tcatagacat gatactagta
     9601 gacctataaa aatacaactt gagcttgatt tgtctgatag aaaaatggag ggggatgaag
     9661 aatcactaaa atcttcacat tctcgtcttc taatttcaac ggtagctgga gcaagaaata
     9721 actctagctt agatacattc tttatctcat tagaagcagt ttataatgag aaagagttat
     9781 ttggaaatcc ggtattaagc tggggctcaa cactagataa tttagtggaa gttcctcaat
     9841 atggtacaag aagtgacatt gataaaatat tccaaatagt ttatgtaaat cccgctatag
     9901 agttagattc cttttttaag cgaaatagaa ggatattgtt ctctgatgat tctaaaactg
     9961 atgaggatgt aaagcttgag gaagagattg agaataacat tgaaaaatta aatgaaaata
    10021 tttctaactt acatttgatt actagtgttc aatcacagtt gactgaagcc tataaaagtt
    10081 atcgtaaaga aaatttagaa attaaaattc aatcagagat atctatttca ggatatttag
    10141 acaatctcac accatacatt aactggaatg atgatactca caattatccg acgtcaggag
    10201 acggtcgtaa aaagctttta tcatatgcta ttaaccattt aatttcagag aaacaataca
    10261 acaagaaggt aattatttat ttaattgagg agccagagaa tagcttacat cgttccgttc
    10321 aaatctctct ttcaaagcaa ctttttgttc agaatattta tgaatacttt tttctaacga
    10381 ctcattcagc agaagttctt tatgaaatgg ataatactca gctcattaag ataaccaatc
    10441 aacaagatgc aacagggcaa tcagtctatt acacagttcc taatgaattt tcaaacttaa
    10501 agaaaaaatt aaataaatcg ttggctcagt caatctttta tgataggatt cttttggtcg
    10561 aaggtccatc agaatattat ctattttctg ctatttttga atatgtaagt cccaatttcg
    10621 aggctgatgg aaaatactta ttacaagttg atggaataaa ttttaaacct tattcagagc
    10681 tatataaggc attagggatt gatttttgga ttaaaactga taatgattta aaagctagtc
    10741 gtggagataa acatgtattt tctcctattg gcttaaatag gtgtattgac ttgcttgatc
    10801 atagtgcgac tcctatatta gataattatc gtatagattt ctcttcaaaa gatgagagaa
    10861 aacagaatat aaagtctaaa aaagaagaat tatatttgac taatcataat ctagtattac
    10921 aattaaatgc agatggaatc tttatatcgg aaattgattt agaaaatgat ttagctcagg
    10981 ttttatccga tagcgagaga aatgaaatga gtaaattaga ttttgtgaat tggttacaaa
    11041 gcagtaaaca atacaatatg ctagaatata taagtaatca tcttactaaa gagattgcgc
    11101 ttaagattgt ggaatcagga tattttaaag ttttggcgga gtttttagac tatgagtgat
    11161 attgctacac aggacaagaa tgtcaaaaaa gaattgttag aataccaagg aaatatttta
    11221 attttagcga acgcaggttc gggaaaaaca acttttttaa ctaaaaagct aaaaagtgat
    11281 tctaaacgat taaataatta tcaaaaatta gcagcaataa cttttactcg aaatgcaacg
    11341 gaggaaataa agcaaaaatt agttgatatt ccggacaacg ttgttgtatc gaccatagat
    11401 tcgtttttag ataaagaaat aatccttcct tttcttaatc agaaatacga aattcaaaca
    11461 tctgtacagt ttagctttcg gatagaccat aattttagcg actatagcac tggaataaaa
    11521 caaatattgc aggatggtat tttcgggact tacgactttc ctacttctaa acacggcaag
    11581 aatttcaaat gtgaagttgc tttagatatt ttgaagacaa tagattctgc gtcagaatat
    11641 ataaaatata aatttaatac tttgtatatt gatgaatttc aagattgtga ccagtctatg
    11701 aatgatttat ttctgtatct aaaaaatgag ttagggattc ctttatttat tgtaggagat
    11761 gataagcaat ctatttatca gtggagagga gcatcaccca aatatataaa taatttatgg
    11821 aaaaacaaaa atgattttag aaaaaagaga tttattggga attttagaag tttgcctaga
    11881 atagtggatt tctctttagc tctgactcct gaagtgactg tcgataatat tagagaagag
    11941 ggttcaattc tatatttaga acctaatcag gattatcc
//
LOCUS       DAVLTT010000056        11502 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLTT010000056 DAVLTT010000000
VERSION     DAVLTT010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11502
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.056"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..333
                     /locus_tag="VYN15_001684"
     CDS             <1..333
                     /locus_tag="VYN15_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1452976.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
     gene            500..1198
                     /locus_tag="VYN15_001685"
     CDS             500..1198
                     /locus_tag="VYN15_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1452977.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1195..2247
                     /locus_tag="VYN15_001686"
     CDS             1195..2247
                     /locus_tag="VYN15_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1452978.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2442..3053
                     /gene="rpsD"
                     /locus_tag="VYN15_001687"
     CDS             2442..3053
                     /gene="rpsD"
                     /locus_tag="VYN15_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV1452979.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            3239..3394
                     /locus_tag="VYN15_001688"
                     /pseudo
     CDS             3239..3394
                     /locus_tag="VYN15_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(3498..3635)
                     /locus_tag="VYN15_001689"
                     /pseudo
     CDS             complement(3498..3635)
                     /locus_tag="VYN15_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            3715..3975
                     /locus_tag="VYN15_001690"
     CDS             3715..3975
                     /locus_tag="VYN15_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452980.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            3929..4150
                     /locus_tag="VYN15_001691"
     CDS             3929..4150
                     /locus_tag="VYN15_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452981.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            4469..5398
                     /locus_tag="VYN15_001692"
     CDS             4469..5398
                     /locus_tag="VYN15_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1452982.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            5412..6335
                     /locus_tag="VYN15_001693"
     CDS             5412..6335
                     /locus_tag="VYN15_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1452983.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWSLIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            6593..8068
                     /locus_tag="VYN15_001694"
     CDS             6593..8068
                     /locus_tag="VYN15_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV1452984.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            8340..9326
                     /locus_tag="VYN15_001695"
     CDS             8340..9326
                     /locus_tag="VYN15_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV1452985.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            9601..10461
                     /locus_tag="VYN15_001696"
     CDS             9601..10461
                     /locus_tag="VYN15_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV1452986.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            10847..11011
                     /locus_tag="VYN15_001697"
     CDS             10847..11011
                     /locus_tag="VYN15_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452987.1"
                     /translation="MDESKYLCYLEKYDALGSGRLLAKVNNTYYMFNKNQIELLRYSN
                     KNAKKERKYM"
BASE COUNT         3601 a         2148 c         2348 g         3405 t
ORIGIN      
        1 ataaatgtta aagaaacatc agacacagca aatggttcat tatcaccttc taactctggt
       61 tctggcgtga ctccgatgaa tcacaatcat gctacaggta ctacagatag catgcctgct
      121 gacaccatga caagttctac caacacgatg gcaggtgaaa acatggctgc ttctgctaac
      181 aagatgtctg atacgatgat gtcagaggat aaagctatgc taccaaatac tggtgagact
      241 caaacatcaa tggcaagtat tggtttcctt gggcttgcgc ttgcaggttt actcggtggt
      301 ctaggtttga aaaacaaaaa agaagaaaac taatcagcta aggaaataaa tgatggatag
      361 tgggctgact aagattagtt taacaactca atcagcaatc aggactttct ttcaatagca
      421 gattaaaatc atcgtaaaac aataaaaata gtgttatact taaagcagta tagcactgtt
      481 tttatcaaag gagagacaga tgggaaagac aattttactc gttgacgacg aggtagaaat
      541 cacagatatt catcagagat acttaattca ggcaggttat caggtcttgg tagcccatga
      601 tggactggaa gcgctagagc tgttcaagaa aaaaccgatt gatttgatta tcacagatgt
      661 catgatgcct cggatggatg gttatgattt aatcagtgag gttcaatact tatcaccaga
      721 gcagcctttc ctatttatta ctgctaagac cagtgaacag gacaagattt acggcctgag
      781 cttgggagca gatgatttta ttgctaagcc ttttagccca cgtgagctag ttttgcgtgt
      841 ccacaatatt ttgcgccgcc ttcatcgtgg gggcgaaaca gagctgattt cccttggcaa
      901 tctaaaaatg aatcatagta gtcatgaagt tcaaatagga gaagaaatgc tggatttaac
      961 tgttaaatca tttgaattgc tgtggatttt agctagcaat ccagagcgag ttttctccaa
     1021 gacagacctc tatgaaaaga tctggaaaga agactacgtg gatgacacca ataccttgaa
     1081 tgtgcatatc catgctcttc gacaggagct ggcaaaatat agtagtgacc aaacgcccac
     1141 tattaagaca gtttgggggt tgggatataa gatagagaaa ccgagaggac aaacatgaaa
     1201 ctaaaaagtt atattttggt tggatatatt atttcaaccc tcttaaccat tttggttgtt
     1261 ttttgggctg ttcaaaaaat gctgattgcg aaaggcgaga tttacttttt gcttgggatg
     1321 accatcgttg ccagccttgt cggtgctggg attagtctct ttctcctatt gccagtcttt
     1381 acgtcgttgg gcaaactcaa ggagcatgcc aagcgggtag cggccaagga ttttccttca
     1441 aatttggagg ttcaaggtcc tgtagaattt cagcaattag ggcaaacttt taatgagatg
     1501 tcccatgatt tgcaggtaag ctttgattcc ttggaagaaa gcgaacgaga aaagggcttg
     1561 atgattgccc agttgtcgca tgatattaag acccctatca cttcgattca agcgacggta
     1621 gaagggattt tggatgggat tatcaaggag tcggagcaag ctcattatct agcaaccatt
     1681 ggacgccaga cggagaggct caataaactg gttgaggagt tgaatttttt gaccctaaac
     1741 acagctagaa atcaggtgga aactaccagt aaagacagta tttttctgga caagctctta
     1801 attgagtgca tgagtgaatt tcagtttttg attgagcagg agagaagaga tgtccacttg
     1861 caggtaatcc cagagtctgc ccggattgag ggagattatg ctaagctttc tcgtatcttg
     1921 gtgaatctgg tcgataacgc ttttaaatat tctgctccag gaaccaagct ggaagtggtg
     1981 gctaagctgg agaaggacca gctttcaatc agtgtgaccg atgaagggca gggtattgcc
     2041 ccagaggatt tggaaaatat tttcaaacgt ctttatcgtg tcgaaacttc gcgtaacatg
     2101 aagacaggtg gtcatggatt aggacttgcg attgcgcgtg aattggccca tcaattgggt
     2161 ggggaaatca cagtcagcag ccagtacggt ctaggaagta cctttaccct cgttctcaac
     2221 ctctctggta gtgaaaataa agcctaaaac ccctttacaa atccagctat tcatggtaga
     2281 atagattttg tgtgaaatat cagcaggaaa gcatgaagct cgtcaacagg tgtcttatga
     2341 caagtaacct tggctgttta ggcgaagggc atctgcacga atcagggctt tctaagtgac
     2401 tatttccacc gaaatattat ttatatcagg aggacattca tatgtcacgt tatacaggac
     2461 catcttggaa acaagctcgt cgccttggcc tttcacttac aggtacaggt aaagaattgg
     2521 cacgtcgtaa ctacgtacca ggacaacacg gaccaaacaa ccgttctaaa ttgtcagaat
     2581 acggtttgca attggctgaa aaacaaaaac ttcgtttcac ttacggtgta ggtgaaaaac
     2641 aattccgtaa cttgttcgta caagctacaa aaatcaaagg cggaatccta ggtttcaact
     2701 ttatgcttct tttggaacgt cgtttggata acgttgttta ccgtcttggt ctcgcgacta
     2761 ctcgtcgtca agctcgtcaa ttcgtaaacc acggtcacat ccttgttgac gggaaacgcg
     2821 ttgatatccc atcataccgc gtaactccag gtcaagtgat ctcagttcgt gaaaaatcat
     2881 tgaaagttcc agcaatcctt gaagcagtag aagctactct tggacgtcca gcattcgtat
     2941 cattcgacgc tgaaaagttg gaaggttcat tgactcgctt gccagaacgc gacgaaatca
     3001 acccagaaat caacgaagca cttgtcgttg aattctacaa caaaatgttg taatatttta
     3061 ttgaataaga taggctttga ggccttgata ttaagcactt tgggacgttc tcccttagtg
     3121 cttttttgat ttctcttagt atccagctat aatcgttgag acataactag accgatatag
     3181 tccaaagtga tatagtaaaa tgaaccaaaa atagtacaca atgtggtata atccttttat
     3241 ggcatattca atagattttc gtaaaaaagt tctctcttat tgtgagcgaa caggtagtat
     3301 aacagaagca tcacacgttt tccaaatctc acgtaatacc atttatggct ggttaaagct
     3361 aaaagagaaa acaggagagc taaaccacca agtatagtgt attgaatcta taacagtaca
     3421 ccttggctgc taaaatattt ctataaatta atttgacttt cctgatagag atgttcacat
     3481 cttatttcaa actactataa aagttctata atctctttat aagatttgcc catcagacaa
     3541 aatagaacga tttgaaggcg tttatgatat ttagctgtac gagagtcttt taaaagtgtt
     3601 ttgatggttt ggatttcttc tttagttgat ttcatatcac tgttatataa tactttttga
     3661 ttttagtcta gtattagtaa gcagactcaa accttagaaa atcttttgag atcattgaca
     3721 ggtgtatcga atcctaccac agattcagca cgtctggttt tggcagaggc taagaaagct
     3781 tttgcagatg atagtttgac agagcaaggt ttacgtgata tcttgcaaac agtcaaagat
     3841 gccattgctt ccctagagtc cattaaggaa agccagtcag caactaagga tggaggacaa
     3901 acagcgggca aagaaacagc aggagaagat gagtctgcaa atcaaactca agaaattagc
     3961 caaggaatta agtaaacttc ttaaagactc aaaccttgaa acagtagata aggatgtcct
     4021 tgaaaactct caaaaagaac ttcaaaaagc agttttgttc ttggcagatg aaaaaggctc
     4081 tgagcatact gaagcagagg tgattgataa tcttaaagag gttattgcta agttgaaagc
     4141 aaacgcctaa taacatatta aaaatctcca gattaggaac tatctctgag ttccctagtc
     4201 tggagatttt tcagtatacc ccgttgttgg atgcttataa cagagtgacg ccatcactgg
     4261 gctaatagag ataaaataaa caattgattt aggacatttg tttgatagtg gtgataaagt
     4321 tttaaatctg ctacataatt tgtggagttt tttctataat taggagttta atctaacctg
     4381 caaataggag tatactaata atgtaatcgt tatcaaaagt ctaaaaaaga atttttagat
     4441 ggatatcaaa ataaaaaggg aggaaattat gaaaaagttt tcaaaaacat tgagagacaa
     4501 ctggatcttt ctcttgatgg ttttgccagg ggcactctgg ttgattctat tcttttacat
     4561 tccagtattt gggaacgtgg ttgccttcaa agactaccac atgaccagta atggtttcat
     4621 agatagtatc ataaatagta aatgggtcgg actcgataat ttcagattct tatttagttc
     4681 aagagacgcc tttattatca cacgaaatac tgtcctctac aatcttggct ttatctttct
     4741 aggtttagtt gtatctgtag ggattgccat tatcctcagc gagctccgtt ctaagagaat
     4801 ggtgaagatt ttccaaactt ctatgttgtt cccttacttc ttgtcttggg ttatcatcag
     4861 tttctttaca gatgccttcc taaatattga taaaggggtg ttcaatcatc tattggaaag
     4921 tcttggtctc aaagaagtca atttctacgc tgacctgggc atctggccct atctcctact
     4981 tttcctaggt atttggaaag gttttggata tagcagtgtc atgtactatg cgacgatcat
     5041 gggaattgat ccaacctact acgaagcagc gacagtggac ggagctagca agtggcaacg
     5101 tattcgcaac gtaaccattc ctcagttgac tccgcttgta actgtattga ccatccttgc
     5161 agtcggaaat atcttccgcg cagacttcgg tctcttctat caaatcccac acaatgctgg
     5221 tcagctttac aatgtaacca acgttttgga cgtatatgtt tttaatggtt tgactcagac
     5281 agcagatatc ggtatggctg cagcagccgg tctttaccaa tccgttgttg gtttgattct
     5341 ggttatccta tcaaacttgc ttgcaagacg agtcgatcca aactcagctt tgttctagaa
     5401 aggaggagaa tatggcaaaa aagaaaatta aaaaagaaaa aattgataat gtcggcattc
     5461 actccttcag taagaaagca gatatcttct tcagtatcat ttcgggtttg attgccctct
     5521 cttgtatcct accttttgta ttcgttatca ttatttcagt gacagacgag aaaagcctcc
     5581 tccaatacgg ctatagcttc ttcccatccc aatttggctt agacggtttt gagtttttgg
     5641 cacagtttaa ggataaaatc ctacaagccc tcttcatctc tgtctttgta accgtagttg
     5701 ggacattgac aaatgtcttt atcacaacaa cctatgccta cgctatttca cggacaacct
     5761 ttaagtatcg cagatttttt accatcttcg tccttctcag tatgttgttc aacgctggtt
     5821 tggtaccagg ttatatcatg gtgacccgtg tacttcagct tggtgacact gtttggtcct
     5881 tgattgttcc aatgcttctc tcaccattca atatcatctt gatgcgttcc ttcttcaaga
     5941 agaccattcc agaagccatt ctcgaatcgg ctcgtatcga tggtgccagt gaggcccgga
     6001 ttttcttcca aatctgtttg ccattgtcac taccaggtat cgcaaccatc acgcttttga
     6061 cagctcttgg tttctggaat gactggttca acgcccttct ttacatcaag agtgataact
     6121 tgtatccatt gcaatatttg ctcatgcaaa tccaacaaaa tatggactac attgccaaag
     6181 cggtcggctt gactggtcaa ctgggagttg ctctaccgaa agaaacaggt cgtatggcca
     6241 tggttgtggt tgcaaccctt ccaatcgcga ttttatatcc attcttccaa cgctactttg
     6301 taaaaggttt gactatcggt ggtgtgaaag aatagtgctt attgaaaaag aacatttctc
     6361 agttcccaac ttcccttgtg tgaagttaat actcttcgaa aatcaaattc aaaccgcgtc
     6421 aacgtcgcct tgccgtagat atatgtaact gacttcgtca gtcttatcta caacctcaaa
     6481 gcagtgcttt gagcagcctg cggctagttt tctagtttgc tctttgattt tcattgagta
     6541 taagatcatt acattgttta taagtttaaa aataaaaaaa ggagttttta tcatgaaaaa
     6601 ctggaaaaaa tatgcttttg catctgctag tgtagtcgct ttggctgcag gtcttgctgc
     6661 ttgtggaaat ttgacaggta acagcaaaaa agctgctgat tcaggtgaca aacctgttat
     6721 caaaatgtac caaatcggtg acaaaccaga caacttggat gaattgttag caaatgccaa
     6781 caaaatcatt gaagaaaaag ttggtgccaa attggatatc caataccttg gctggggtga
     6841 ctatggtaag aaaatgtcag ttatcacatc atctggtgaa aactatgata ttgcctttgc
     6901 agataactat attgtaaatg ctcaaaaagg tgcttacgct gacttgacag aattgtacaa
     6961 aaaagaaggt aaagaccttt acaaggcact tgacccagct tacatcaagg gtaatactgt
     7021 aaatggtaag atttacgctg ttccagttgc agccaacgtt gcatcatctc aaaactttgc
     7081 cttcaacgga actctccttg ctaaatatgg tatcgatatt tcaggtgtta cttcttacga
     7141 aactcttgag ccagtcttga aacaaattaa agaaaaagct ccagacgtag taccatttgc
     7201 tattggtaaa gttttcatcc catctgataa ctttgactac ccagtagcaa acggtcttcc
     7261 attcgttatc gaccttgaag gcgatactac taaagttgta aaccgttacg aagtgcctcg
     7321 tttcaaagaa cacttgaaga ctcttcacaa attctatgaa gctggctaca ttccaaaaga
     7381 cgtcgcaaca agcgatactt cctttgacct tcaacaagat acttggttcg ttcgtgaaga
     7441 aacagtagga ccagctgact acggtaacag cttgctttca cgtgttgcca acaaagatat
     7501 ccaaatcaaa ccaattacta acttcatcaa gaaaaaccaa acaacacaag ttgctaactt
     7561 tgtcatctca aacaactcta agaacaaaga aaaatcaatg gaaatcttga acctcttgaa
     7621 tacgaatcca gaactcttga acggtcttgt ttacggtcca gaaggcaaga actgggaaaa
     7681 aattgaaggt aaagaaaacc gtgttcgcgt tcttgatggc tacaaaggaa acactcacat
     7741 gggtggatgg aacactggta acaactggat cctttacatc aacgaaaacg ttacagacca
     7801 acaaatcgaa aattctaaga aagaattggc agaagctaaa gaatctccag cgcttggatt
     7861 tatcttcaat actgacaatg tgaaatctga aatctcagct attgctaaca caatgcaaca
     7921 atttgataca gctatcaaca ctggtactgt agacccagat aaagctattc cagaattgat
     7981 ggaaaaattg aaatctgaag gtgcctacga aaaagtattg aacgaaatgc aaaaacaata
     8041 cgatgaattc ttgaaaaaca aaaaataatc agctaaattg atttcgtgta ttcattccta
     8101 actcctaaaa taagaatcac tgctttcctc aggttggtct ggggagggca gtggtttttt
     8161 tggcacaagg atatagatat ccctgttttc tcttgtcctt attttaacca ttcaggaaat
     8221 ttcgagaatc ctctacaatt tccagtcaaa taaattgcat tcgttttctc aagcaggtat
     8281 actagtatgg ataaataaaa aatttagaaa atttaagaat agaaaagaga acaaatctta
     8341 tggcaaaaga tattcgtgtc ttactttact acctttatac tccaattgaa aatgcagagc
     8401 aatttgctgc agaccacttg gctttctgta aatcaatcgg ccttaaaggc cgtatcctag
     8461 tcgctgacga gggaattaac ggaacagttt caggtgacta tgaaacaact caaaaataca
     8521 tggactacgt tcacagcctt ccaggaatgg aagatctctg gttcaagatt gacgaagaaa
     8581 gtgaacaagc cttcaagaag atgtttgttc gctacaagaa agaaattgtc caccttggtt
     8641 tggaagacaa cgactttgac aatgacatca acccacttga aacaacaggt gcttacttgt
     8701 ctccaaaaga gttcaaagaa gcgcttcttg ataaagatac cgttgtcctt gacacacgta
     8761 acgattatga gtacgaccta ggacatttcc gtggggctat tcgcccagat attcgcaact
     8821 tccgtgagtt accacaatgg gtccgtgaca acaaagaaaa attcatggac aagcgtgtcg
     8881 tggtttactg tacaggtggt gttcgctgtg agaaattctc aggctggatg gttcgtgaag
     8941 gttacaaaga tgttggccaa ttgcacggag gaatcgcaac ttacggtaaa gacccagaag
     9001 ttcaaggtga gctttgggat gggaaaatgt acgtctttga cgagcgtatt gccgttgatg
     9061 tcaaccatgt caacccaacc atcgtaggga aagactggtt tgatggaaca ccatgtgaac
     9121 gttatgtcaa ctgtggaaat cccttctgta accgtcgtat cttgacatca gaagaaaatg
     9181 aagacaagta ccttcgtgga tgctcacacg agtgccgtgt tcacccacgt aaccgctatg
     9241 tttcaaaaaa tgaattgaca caagctgaag tgattgagcg cctagccgct atcggtgaaa
     9301 gcttggatca ggcagctact gtataagatc aaacagtcct taggggctgt ttttctatgc
     9361 tttgtactca aaaatctaat actcaatgaa aatcaaagag caaactagga agctagccgc
     9421 aggctgctca aagcactgct ttgaggttgt agataagact gacgaagtca gttacatata
     9481 tctacggcaa ggcgaagctg acgcggtttg aagagatttt cgaagaatat aaagtttgtt
     9541 tttgtatctt tcagaaaaat aaggtatact gtatgtaaac gatttcaaag gagtccagtt
     9601 atggcgaaaa cattttttat tccaaataaa cagagcattt taggagaaca agagattttg
     9661 aatgccaagt cgatcttggc cttgctagac ggtttggagt cacatagcta tgatgtagtc
     9721 tatctccgtc agcctcttaa tcgtctcgag tatattgagt gtgcgatagt ggggcaatca
     9781 caatttctct ttaaggtcag ttatgctgat ggtcaaaagg cttaccgtgt cgatcttcct
     9841 gacctactaa caaagacaga ctggcagatt atcaagtcat ttttagatgc tttgcttgct
     9901 tatacaggga ctgatattga agggctagat ggttttgatt ttgaagctta tttccaagca
     9961 agtattcaag cctatctagc agaccctgta gctcgtttta cgatttgcca aggaattttt
    10021 aatcctattt tctttagtcg tgagaacttg aaaagctttt tagaggcaga tggcttggct
    10081 cagtttgaag cgcgtgtgcg tgcggttcaa gagacagatg cctactttgc gagagtttcc
    10141 ttctatcagg atggagaagg aaaagtgcat ggcgtttacc atctagctca aggagtcaag
    10201 acagttttac cgagagaacc gtttgttcct gcagcctata ttgagcaatt ggtggataag
    10261 gaagtccagt gggagattga cttggttcaa atcacaggag acggctctaa accagaagac
    10321 tatgaatcca tagctcgctt ggactatgca aaattcttag aggtattacc cccatctttt
    10381 taccaccaac tagacgccaa tcaaatagaa gtgcaaccca tattagacaa agattttaaa
    10441 acattagcac aagaaaagta aagcagaagc aggtcaatcg acttgctttt ttgaaataga
    10501 aaaatcctgc caaggatgac aggattgcta ctcaatgaaa atcggctcta taatatttgt
    10561 agtgggtaaa tcccctatgg atattatgga gcctattata acataaacga gtgacttttt
    10621 aagtaatgac tgcgcttttc aatgatggga gaggtatggt attggtttta atcacaaatt
    10681 atcagaaaat tttctatttt tttgttgaca atattttgaa tatagtatac aataatttca
    10741 ttaactcgac aatcactaga tatatgcaat ctaatcgtaa ttttatagga ggagtccgct
    10801 gatgtcaaac gagaatgcac agaatttgat gtggagataa tttaggatgg atgaatcaaa
    10861 atatttgtgc tatcttgaaa aatatgatgc tttaggctca ggacgattat tagctaaagt
    10921 taataatact tactatatgt ttaacaaaaa tcagattgaa ctcttacgat actcaaataa
    10981 aaatgctaaa aaagagagga aatatatgta aagttttcct gctatactag taataccata
    11041 gaccaattta ttgattattt ttacaaacaa ggaatacttg ttaagaaaaa ttcatttgat
    11101 gataatgggt tgaagttttt gtcaatatat cgcagattga caagattcta tattccacaa
    11161 aaattaaatg attatattgg acaaaaaaaa tctaaattta tacctttcct tccgaatcct
    11221 gtactaatta caaaagtaat gctatattgt agtcctattt tagctttatt tctttgttat
    11281 gcttgttatg atattcaact aaacatttca aaagttccaa gaaatattat cacattttta
    11341 gtaggaagcg tggtagctat tatacacgag ctattaataa tgatatatta tttgaagtca
    11401 gggagagtac ctggacgcat atatattaga attgtttatc tcgtagtcat atcttttgga
    11461 acagaatggg gtgctagtta tagtgaaaag aaagttttta ga
//
LOCUS       DAVLTT010000057        11361 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLTT010000057 DAVLTT010000000
VERSION     DAVLTT010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11361
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.057"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            149..325
                     /locus_tag="VYN15_001698"
     CDS             149..325
                     /locus_tag="VYN15_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1452988.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            727..2940
                     /locus_tag="VYN15_001699"
     CDS             727..2940
                     /locus_tag="VYN15_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV1452989.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNFLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSRDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(3162..3638)
                     /locus_tag="VYN15_001700"
     CDS             complement(3162..3638)
                     /locus_tag="VYN15_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV1452990.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            3861..7064
                     /locus_tag="VYN15_001701"
     CDS             3861..7064
                     /locus_tag="VYN15_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV1452991.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSTWVDQKNSSADASTRVIEAKGG
                     AITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WLHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKSPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKGINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            7417..7802
                     /gene="tnpA"
                     /locus_tag="VYN15_001702"
                     /pseudo
     CDS             7417..7802
                     /gene="tnpA"
                     /locus_tag="VYN15_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(8181..8810)
                     /locus_tag="VYN15_001703"
     CDS             complement(8181..8810)
                     /locus_tag="VYN15_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV1452992.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(8820..9821)
                     /locus_tag="VYN15_001704"
     CDS             complement(8820..9821)
                     /locus_tag="VYN15_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV1452993.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(9852..10493)
                     /locus_tag="VYN15_001705"
     CDS             complement(9852..10493)
                     /locus_tag="VYN15_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV1452994.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAMDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(10512..11327)
                     /locus_tag="VYN15_001706"
     CDS             complement(10512..11327)
                     /locus_tag="VYN15_001706"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV1452995.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIQAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         3593 a         1970 c         2445 g         3353 t
ORIGIN      
        1 gtaaaaaagc aaaaagaatg cgttttatat ttgggtttga ggcttataaa ataggataag
       61 cgtgctgaaa acttagatat gacaaacaaa ataaaatttt taaaagctac agagaaacat
      121 ggtataatgt atctaaagga ggtagcatat gtccttagat atagataaag aaaagatgac
      181 aatcatggga atagcttttg aaaaccgatc cgtttttaag agtgtttggt atgctttaag
      241 tacaaatatg attgaaggat ggcgacctac ggttagtgat gttgaaaaat tacgagatga
      301 agctcttgct ctggggatga cttaatgaag cgcaactgtt atgaatctta tgactatgtt
      361 gatccggata atttatatac cgatccgggt tcttcagttc taagaaataa gcaggaagga
      421 aaaaagcacg cgagcttgaa tatcgtatga ttgctagtaa gagtttgaaa ttatttatca
      481 atcctatctt agttaatagt ttaaaagtag tttgtttcac aactgcataa gcttagaaaa
      541 gttgaaaagt gataactctt taataaactc ttggtttgtt aaaagatatt ttgtccacta
      601 catttttttc aattgactat tatttgtcat agatataaca gatagaacat tgcattcaga
      661 ataatgaaaa acgcatcaaa aatggtgcgt tctgttttta tgctaccata aaaggaggaa
      721 aacaaattga aaatttttaa gggagagttt tatcgaatct ctgtattaac agacaagcta
      781 gtaaggttag aatactctcg aactggaaat tttgaggata gaacgacaca acttatctat
      841 aatagagatt ttggccaaat ttcgttagat tatatcgaga catcaaatgt actagatatt
      901 atgacggact attttcatct gcactttaat aaaggagaat ttaacgccga aaatttattt
      961 atagaattaa aaggaaattt tgccgtatat ggtagtcgct ggtattttgg tgaatctatt
     1021 gaaacgttaa aaggaacagc tcggactctg gataaggcag atggagcaat ctcgttagaa
     1081 gatggaatta ttagccgaaa tggtatagcc ttattggatg attctcaagg atttatttgg
     1141 gatgaacaat ctggttatat tgagagagaa aatcaaattg acctgtattt ctttgcctat
     1201 gggcatgatt atagaggagc aatcagagac ttttaccatt tgactggttc aacacccttg
     1261 ttgccaagat atgctttagg caattggtgg agtagatatt ggccttatac gtcggatgaa
     1321 tacttggatt taatagacag atttgaaaca gagaaaattc cattatctat cggtgtgtta
     1381 gatatggatt ggcatataac tgacattcca gctcgttttg gaagtggctg gacaggatat
     1441 agttggaata gaaacttaat accaaatcca gaacagttat tgcaacaact tcatgataga
     1501 aagttaaaac tctccttaaa tgtccatcct gctgatggga tacgggctta tgaagaagct
     1561 tatcctcaaa tcgcaaaacg gttggggtta aatgtagaac tagaagaacc tgctattttt
     1621 gattttttta atccctcttt tagggaagcc tactttaaag atgttcatta tgagctagaa
     1681 aagcagggag tagatttttg gtggattgac tggcaacaag ggacacaagg tatgctagat
     1741 ccactttggc ttttaaacca ttatcactat caggatagtt gtaaaaatgc agaaggtggt
     1801 ttgattttat caagatatgc aggtcctggt agtcaccgct accctgttgg tttttcaggg
     1861 gatactatta ttagttggaa tttcttaagg tttcaaccct attttacagc gacagcatct
     1921 aatatcggtt atagttggtg gagtcatgat atcggtggac atatgttggg ggattatgac
     1981 gaagagctac aaactagatg gctacagttt ggtgttttta gtccgattac tcgattacat
     2041 agttctagaa gtccttttaa tagtaaagaa ccttggttct tttcagaaac aacatctaag
     2101 attatgaaga aataccttcg tttgagacat cagatgattc cctatctata taccatgaat
     2161 gtaaagacac atgaggaagg tgccccatta atcagtccaa tctattattt ctatccagag
     2221 aatgatgaga gctataatgt tccaaaccaa tacttttttg gaacagaact gatggtggct
     2281 cccattgtag aaaagatgga tttgacattc caatctgcaa aagtagatgt atggttccct
     2341 gaaggtgaat ggtatgactt cttttcagag aaaaaataca caggtggtgt gaagttaagt
     2401 gtttataggg acatctcgac tacgcctgtg tttgcaaaaa gtggtgcaat cattcccttg
     2461 gttggttctg agataggtat gggtgttgat ttacctgagg ttgtagattg gtatgtattc
     2521 ccaggcaaac aacattcttt tgaaatgctt gaagatcaaa atggtcaaag atataaaaca
     2581 agattatcaa tcgattggga aatgggaatg gtagagttag cattacaagg agattctagt
     2641 atcgttccaa gcaatagaaa acatagaatt cattttaaag gaacgaatgt gtctataatt
     2701 gaattgccaa ataagaatga tacagctaaa tttgaatgga aagataataa aaggacatct
     2761 ttaaatgacg aagtttttag actactaaag acagcttctc ttccatatga attaaaagat
     2821 agattgttaa atcaattcat caatgcgaaa aactctcgtg acttaatgaa tatcttgcat
     2881 catcaggata aggaattgag agggcgtttg ttggaaatga tatttactag ccaaaactaa
     2941 ttgaaataat tagaaagtca tttgtttagt gtatatgaag attctgtatg gtattcgtta
     3001 tcactggtca cattgaaatt gtgaaataag cacctacaac atagacttta caacacttca
     3061 tgtttcatat catggggtgt ttttctattt aagtcaaagc ccatcaaaaa atctcactat
     3121 tcatcaggtt aaaggaaacc taatcatagt gagattgtga attatagtag agtttgtatc
     3181 gcctcttcaa tttgttttgg gtctgttttt gaagaaaagc gttcaaagac ttgcccatct
     3241 cgaccgatga gaaacttagc gaaattccat tcgactcgtt ttcctagtgg gccggatttc
     3301 tggtctttta accagacata gagagggtct gcttccttac cgttgacctt aatcttggca
     3361 aaacgtggga aggtggtttg aaaatgtagg ctacagaagg cgttgatttc ctctgcgctg
     3421 ccgggtgctt gtcccataaa ctgattgcaa gggaaatcca atatttcaaa gccctgatct
     3481 tgatagcgtt catagagttc ttgaagtccc tggtactggg gcgttaaacc acatccagta
     3541 gcagtgttga caatcaagag aactttacca cgatagctat ccaagggagt tgcttggttg
     3601 ttttggttca aaacggaaaa atcataaagt gaagtcatga gggcctcttt tctttttcta
     3661 cattgtaaca gtttttactt ttttcgtcga gtcggatgga agatattgtt gaagaataag
     3721 ccttcaatat gatagaaacc gtttacaaat aactttaaaa atggtatgat ttaattaaac
     3781 cggtttactt tgttgctata aatctctaat ttgagattta gttcctattg attttacaat
     3841 atgtttattg gagtgtatac atgcaaacaa aaacaaagaa gctcattgtg agtttgtctt
     3901 cacttgtttt atcaggattt ttattaaacc attatatgac agttggagcg gaagaaacga
     3961 ctacgaatac cattcagcaa agccagaagg aagttcagta tcagcaaagg gatacaaaaa
     4021 atttagttga aaatggtgat tttggtcaga cggaggacgg aagcagtccg tggacaggaa
     4081 gcaaagctca ggggtggtca acttgggtag accagaagaa tagttctgca gatgcctcaa
     4141 ctcgagtcat tgaggctaag ggtggggcta tcactatctc aagccatgag aaattaaggg
     4201 cagcggttca ccgtatggtt cctattgaag ctaagaaaaa gtataaactg cgtttcaaga
     4261 ttaaaacaga tcataaagtc gggattgcca aggttcgtat cattgaggaa agtggtaagg
     4321 acaagcgatt gtggaattct gcaacgacgt caggaacaaa ggactggcag accattgaag
     4381 cagactatag cccgacttta gatgttgata aaatcaagct ggagttattc tatgaaacag
     4441 gaactgggac tgtttccttt aaggatattg agctggtaga ggtagcagac cagctttctg
     4501 aggattctca aacagataaa cagcttgagg aaaagattga tttaccaatt ggaaaaaaac
     4561 atgttttttc tcttgcggac tatacttata aggtagaaaa tcctgacgtt gcttcagtca
     4621 aaaatggaat tttagaacct cttaaggaag ggacaaccaa tgtcattgtc agtaaagatg
     4681 gcaaggaagt gaaaaagatt cctttgaaga ttctagcctc tgttaaggat gcatacacag
     4741 cccgtttgga tgactggaat ggcatcatcg ctgggaatca atactatgat tctaaaaatg
     4801 aacagatggc caaattaaac caggaattgg aaggaaaggt agctgatagc ctatctagta
     4861 tttcaagtca ggcggaccgc acctatttgt gggaaaaatt ttcaaattat aaaatgtctg
     4921 caaatctgac tgccacttat cggaaattgg aggagatggc caagcaagtg accaatcctt
     4981 cttctcgtta ttatcaagat gaaactgtcg ttcgaacagt cagggattcc atggaatggc
     5041 tgcataaaca tgtctacaat agtgaaaaga gcattgttgg gaactggtgg gattatgaga
     5101 tcggtacacc tcgtgccatc aacaatacct tgtctctgat gaaagaatac ttctctgatg
     5161 aggaaattaa aaaatataca gatgtaattg aaaaatttgt accagacccc gaacatttcc
     5221 gaaagacgac tgataaccca tttaaggctc taggtggaaa cttagttgat atgggaagag
     5281 taaaagtaat agctggttta ctgcgtaaag atgatcaaga aatttcttct accattcgct
     5341 cgattgagca agtgttcaag ttggtagacc aaggtgaagg tttttatcaa gatggatcct
     5401 atatcgacca caccaatgtt gcctatacgg gtgcttatgg gaatgttttg attgatggcc
     5461 tgtctcaact gttgccagtc attcaaaaga ccaagagtcc aatcgataaa gataaaatgc
     5521 aaaccatgta ccactggatt gataaatcgt ttgctccttt gctggtgaat ggagaactga
     5581 tggatatgag tcgtggacgc tcgatcagtc gtgcaaatag cgaggggcac gtggccgcag
     5641 tagaagtact aagagggatt caccgaatag cggatatgtc tgaaggagaa accaaacaac
     5701 gtttgcagag tcttgtgaag accattgttc aatcggatag ttattatgat gtctttaaga
     5761 atttgaagac ttataaggat atcagtttga tgcaatcctt gttaagtgat gcaggagtcg
     5821 caagtgttcc aagaccaagt tacctatctg cctttaacaa gatggataaa acagccatgt
     5881 acaatgcaga gaaagggttt ggatttggct tgtcactctt ttccagtcgt accttgaatt
     5941 acgaacacat gaacaaggaa aataaacgtg gttggtatac gagtgatggg atgttctatc
     6001 tttacaatgg cgatttgagt cactatagcg atggctactg gccaacagtt aatccatata
     6061 agatgcctgg tacaacagag acggatgcta agagagcgga tagcgataca ggtaaagttt
     6121 taccgtctgc tttcgttgga acgagcaaac tagatgatgc caatgcgaca gcaaccatgg
     6181 atttcaccaa ctggaatcaa acattgactg ctcataagag ctggtttatg ctaaaggata
     6241 agattgcctt tttaggaagc aatatccaaa acacttcaac agatactgct gcaactacaa
     6301 tcgaccagag aaaactggaa tcaagtaatc catataaagt ctatgtcaat gataaagaag
     6361 cctcccttac agaacaagaa aaggattatc ctgaaaccca aagtgtcttt ttagaatcgt
     6421 ccgattcgaa aaagaatatt ggttactttt tctttaagaa gagttcaatc agcatgagta
     6481 aggctttgca aaagggagcc tggaagggta tcaatgaagg acagtcagac aaggaagttg
     6541 aaaatgaatt tcttacgatt agtcaggctc ataagcaaaa tggagattct tatggctata
     6601 tgctcattcc taacgtggat cgtgccacct tcaatcaaat gataaaagag ttagaaagta
     6661 gcctcatcga aaataacgaa acccttcagt ctgtttatga tgctaaacaa ggagtttggg
     6721 gcattgtgaa atatgatgat tctgtctcta ctatttccaa ccaattccaa gttttgaaac
     6781 gtggagtcta taccattcga aaagaagggg atgaatataa gattgcctac tataatcctg
     6841 aaacccagga atcagctcca gatcaggaag tctttaaaaa gctagagcaa gcagctcagc
     6901 cacaagtaca gaattcaaaa gaaaaggaaa aatctgaaga ggaaaagaac cattcggatc
     6961 aaaagaatct ccctcagaca ggagaaggtc agtcaatctt ggcaagtcta gggttcttgc
     7021 tacttggggc attttatcta ttccgtagag gaaagaacaa ctaatttgtt catcatctag
     7081 atgaattaca tgaaactgtg gaaaatagaa aaaatccgaa gaaggccaaa tatcttcgga
     7141 tttttctttt aaaaaaggat aagttgatac ttatcctttt ttacttcatt attatgtgac
     7201 tatagcgttt tgaaactaga atagaacgtt ataactgcta aaagatttct ataaattcat
     7261 ttgattttcc taatcaattt gttcgtatcc tatttcactc cactatataa gtccgtctcg
     7321 ctccgtgagg tgcgcgtcga aggttatacc aaaaaaactc caaacgcgat acaataaagg
     7381 tattcaatcc aattgtaaag cgaaaggaga aaaaatatgg cacaaaagac tcatagttta
     7441 tcatacacaa agtggatgtg ttctatcata ttgtgttcac ccctaagtat agacgaaaag
     7501 tcatctataa tcaatataga agtagtttag gcgaaatatt tcatcgcttg tgtagttata
     7561 aaggtgttga aatgatcgag ggtcacttaa tgccagacca tgtacacatg ttagtcagta
     7621 ttccactaag gctaagtgtt tcaagtttta tggggtattt aaaaggcaaa agtgcactca
     7681 tgatgtttga caaacacgcc aatctcaagt acaagtttgg gaatcggcat ttctgggcgg
     7741 aaggttatta tgtaagtaca gtagggctta atgaagccac aattaagaaa tatagtcaag
     7801 attaaagaaa ttatcgagtg gatgatttct tcacgagtat gaaaatttga gaactagtaa
     7861 agtatgatat atagtaaaat gaaataagaa caggacaaaa tcgatcagga cagtcaaatc
     7921 gatttttaac aatgttttag aagtagaggt atactattcc agtttcaatc tactatagca
     7981 ctagataaat tgagtgtaaa agaatatgag gatcccttta gggatagtgg taagtaatac
     8041 caaagtctct taaagaggca agtgacgagt caagagcaat aaggcttgaa caacgtgaaa
     8101 gccagcgtct ttaggcgctg gctgatgatt tgggcttata gctctgagat aaaccacccg
     8161 ttagacgggt agttatgatt ttatctgagt gtaatatact gttgggcaat ctcgctgatg
     8221 cggtcaaagt tgccttggga agcgagttta ttgagttcgc caccaattcc aacggcgtct
     8281 gcaccagcag cgaaccattg agggatgttg tttagaccga ctcctccggt taccattacg
     8341 gaaacttgtg ggatcggtgc cttgactgca gagatatatg ctggactgag agcactacct
     8401 gggaagagtt tgatgatttc actaccggct tcaagtgcag tcgtgatctc tgtgagggta
     8461 atacagcctg gaatgtacgg tgtgctgtag agattgcaca ttttcgcagt ttcagcatgg
     8521 aaagatggag aaacaacgta atttgctccg gctagaatgg catctctagc agttacggca
     8581 tcaagcacag tacctgcacc gatacaaaca ctctgatcgt cctgatacaa gtctacaagt
     8641 tccttgatga tttgtcctgc atactgattg gtataggcga tttcaatagc tttgataccg
     8701 cccttgatac aagcaatcga ggcttgcagt ccttcttcct ttgtatttcc tcgaatgaca
     8761 gcgacaattt tctgtttttt tagttcaata atcgtatctg atttggtcat gtaattctcc
     8821 taacgaatga tatcttgtgc atttgccagt aaattttcaa tactagttgc ggaagtggag
     8881 agatggtctc ctggaagagt gcatttgaga gttgcgctcg caactgcaaa gtcaatggta
     8941 gtttttaggg aggaatgatg gagtagttgg taaagggcac cagatataaa ggcatccccg
     9001 ctaccaattc gttgatagac tgcagttttt agttggacag actcttcaaa tcgttcttcc
     9061 agagcatagg cttgatagac atttttgtct tgctcatcac tagagcggag ggtatggaaa
     9121 atggccttga aaccataggc ttcttttaaa agtcgcatgc gattttccac ctcttctagg
     9181 ctagcactgt ctcttggaaa catctctaga ttttggtcat caatcatgag aggatcaata
     9241 ccgaagcaat agtcagtaaa acgtgcaaac ttagaaaatt catacttggc ttctaggact
     9301 gaaatcatct ttgttctcag attgagatcc attgaaacga caattcctcg gcgcttggct
     9361 tcttccaaga gtaggagaag gatcgcacgg acctcttgac cgatagctac ggtgattcca
     9421 ctaaaatgaa aatggctaat cccctgaaag agagaatcca tatctagcat gtttggccga
     9481 atctggctga tacttgtatg cttacgatcg tagaaaactt cactttgacg acaaccaaag
     9541 ccgttctcca aatagtagag gccgattcga tcgccaagcc gacagattga actggtatcg
     9601 atttggtgct gtttcaagaa tgtgagaaaa cgatctccaa tctcgttggc agggagtgcg
     9661 gtaaagactt tcgttgagat acccagggct tgcaaattac aagcgatgtt aatttctgat
     9721 ccgccaaaat aagtcgaact ggcaacatga tcgccgatac tggtggcatc taatggtgag
     9781 attcgaatta atggttcgcc aaacagtaat attttcgtca tccattagtt cctttctggt
     9841 ttagaatagc tttacttggc taatacttct ttcaaataag cagcgacttc atcatcttgg
     9901 cagttttcaa agaagtattc ttggaaatat ttgccagaga tggtgtcttt gaggaagtct
     9961 tggtcgattg ttttaaggat ggtcatcaaa tcattgtggg tgatttgttt cacctcgttt
    10021 aagatacgag cgttgcgttg ttcagggatt acacgttctc ttgggtagcc accgcccatt
    10081 tcttcagcaa ataagcgttc aaacatcaat ttgagggtca gttctgcccc ccagccaaat
    10141 cctttggcat aagggataga caaggcgtta ccaccattga tttgagaata aaggtaagcg
    10201 tcagttgggt ccattgctag accacagaca acaccaggga agctgtttaa agcaagcata
    10261 gcccctacac ccgtaccaca gccggtaaca acaaagtcaa ctgcctttgt atttaaaagg
    10321 atggcagcca ttagtccgtt ctgcacataa gttaattgac tttctccttc ttctccacgc
    10381 ataccatagt taaataattg gtagtctttt ttatctgtcg cttcttttag actatcgtaa
    10441 ataatgtgat tcttgctagc ttgactattt tcattgatta atgcgatttt cataagatct
    10501 tctttctatt tttactcagg ttgttttccg atgtaggcta agataccgcc atctacatat
    10561 aggatgtggc cattgacaaa attgctggca tcactagcga gaaagacagc agggcccatc
    10621 aaatcttcag gatttcccca acgtgcagca ggtgtttttg caatgatgaa ctggtcaaat
    10681 gggtggcgag aaccatcttc ttgcaactca cgaagaggtg ctgtttgagg agtggcaata
    10741 taacccggtc caattccgtt acattggata ttggctccac cgtattcaga cgcaatgttg
    10801 cgggtcaaca ttttcaagcc ccctttagca gcagcataag cgctaactgt ttcacgtccc
    10861 agttcgctca tcatcgaaca aatattgata atctttccat gccctttctt tatcatagaa
    10921 ggaataactg cctttgaaac gataaatggt gcgtttaagt caatatcgat gaccttacgg
    10981 aaatcagcgg cgctcatttc gcacattgga actcggcgga taataccagc gttattaacg
    11041 aggatgtcaa tgacaccaac ctcttgttcg atttgcttga ccatggcttg gataccgtcc
    11101 tcgtctgtca cgtcacagac atatccatgg gcttggatgc caacttcacg ataagcttca
    11161 atccctttat tgaccagatc ttgattgata tcgttaaaga caatagtagc gccggcttca
    11221 gcgtaggatt tggcaatagc aaatccaatt ccataagaag cgccggtgat gagagcaatt
    11281 tttcctttta aagaaaactg ctcaattgag aatgatgtat ttgtcatttg atacttcctt
    11341 tcaaatttgt taagacttct c
//
LOCUS       DAVLTT010000058        11215 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLTT010000058 DAVLTT010000000
VERSION     DAVLTT010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11215
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.058"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            73..342
                     /gene="blpJ"
                     /locus_tag="VYN15_001707"
     CDS             73..342
                     /gene="blpJ"
                     /locus_tag="VYN15_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEV1452996.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            411..560
                     /gene="blpO"
                     /locus_tag="VYN15_001708"
     CDS             411..560
                     /gene="blpO"
                     /locus_tag="VYN15_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV1452997.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            664..783
                     /locus_tag="VYN15_001709"
     CDS             664..783
                     /locus_tag="VYN15_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1452998.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            1569..1952
                     /locus_tag="VYN15_001710"
     CDS             1569..1952
                     /locus_tag="VYN15_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1452999.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            2004..2693
                     /locus_tag="VYN15_001711"
     CDS             2004..2693
                     /locus_tag="VYN15_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1453000.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            2735..2968
                     /locus_tag="VYN15_001712"
     CDS             2735..2968
                     /locus_tag="VYN15_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453001.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            3119..3730
                     /locus_tag="VYN15_001713"
     CDS             3119..3730
                     /locus_tag="VYN15_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1453002.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            3891..4685
                     /locus_tag="VYN15_001714"
     CDS             3891..4685
                     /locus_tag="VYN15_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV1453003.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            4682..5317
                     /gene="trmB"
                     /locus_tag="VYN15_001715"
     CDS             4682..5317
                     /gene="trmB"
                     /locus_tag="VYN15_001715"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV1453004.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            5443..5922
                     /gene="rimP"
                     /locus_tag="VYN15_001716"
     CDS             5443..5922
                     /gene="rimP"
                     /locus_tag="VYN15_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV1453005.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            5966..7102
                     /gene="nusA"
                     /locus_tag="VYN15_001717"
     CDS             5966..7102
                     /gene="nusA"
                     /locus_tag="VYN15_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV1453006.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7124..7417
                     /locus_tag="VYN15_001718"
     CDS             7124..7417
                     /locus_tag="VYN15_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV1453007.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            7410..7709
                     /locus_tag="VYN15_001719"
     CDS             7410..7709
                     /locus_tag="VYN15_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV1453008.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLAKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            7726..10518
                     /gene="infB"
                     /locus_tag="VYN15_001720"
     CDS             7726..10518
                     /gene="infB"
                     /locus_tag="VYN15_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV1453009.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSETAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            10769..11119
                     /gene="rbfA"
                     /locus_tag="VYN15_001721"
     CDS             10769..11119
                     /gene="rbfA"
                     /locus_tag="VYN15_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV1453010.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3436 a         1967 c         2563 g         3249 t
ORIGIN      
        1 taaaaaaaat ctatttgttt attgaattta agactttggt aacaaattga aaataaaaag
       61 gaggtattca tcatgaatac aaaaatgttg tcacagttag aggttatgga tactgaaatg
      121 cttgcgaaag ttgaaggggg gtatagctcc actgattgtc aaaatgcact gattacagga
      181 gtcactacgg gaattataac tggtggaact ggagcaggtt tggccacttt aggagtagct
      241 ggacttgctg gtgcatttgt tggagcacac attggtgcaa ttgggggtgg attaacatgc
      301 ttaggaggta tggttggtga taaattggga ctaagttggt aagacttata gtaaaattat
      361 gaggattcta ttctgattta ttttagtttt ttaaaaaagg agtatttgtc atggatacaa
      421 aaatgatgtc acaattttct gttatggata ctgaaatgct tgcttgcgtt gaaggtggag
      481 atattgattg gggaagaaaa attagttgtg cagcaggggt tgcatatggc gcaattgatg
      541 ggtgtgcaac aacggtttga catttctatt gggaccattt gctataggaa taggtgtaac
      601 tggtgctgca ggtggagcta tacttggagg tgtagcctat gcagcaatat gttggtggta
      661 attatggatt ttaaaagttt tattattggt ttagtagttg gtatatttgg tccttatatg
      721 gatgacttaa ttagaaaaat attttcaaaa tcttccaaaa aggatacgga tagtactctc
      781 taaaaaataa atttctcccc tgtatttgct agcttaattt acaggggagt ttctttaata
      841 ttgtttcgcc tgtcaaaatg atatgtgata gcaggatgaa aagtctacaa acaagttggt
      901 atcaatacaa tataaagagg aaagtatgtt tttaatgctt actttttaaa ttttttaaca
      961 attcaagatg tttcgatgac aattcaagat ttggatgaaa aattttaaaa aacaatgata
     1021 tactaaactt gtcaaagttg caacgggtgc tgctacatta tgttaaaaat cgctcttgat
     1081 tgataagttg gatttgttag gaaaggagta aataattatg gataagaaaa agatagtttc
     1141 gactataata tgtatagtat ttcttgtagt gtcagtagat aattttttta gagacttaac
     1201 cccgttactg ttcattttaa atattattgg cctgtcttgc ttttcagtgc taacatacat
     1261 taacataaaa gagatactct taaatataag taaatgatga tttggttagt cctagaacca
     1321 atcaacttat gtttatcggc ttggcagatt ttatgtttgt catttgtttg tatagaggta
     1381 tttcagaaac agaattctat caacaactaa tcgcttatat aggtgtattc tctgcttgtt
     1441 tatcacgctt ctgctcatgt ggggcttgaa gtattataaa aagtagcttt ctatcctttt
     1501 ctgacaggat atttgagtag aaggctctat taaattgtta gtgaaataaa tgaatggagg
     1561 tatttaatat gaaatacaga ttattttttg ttattttctt gagtagtgtg ttggatattc
     1621 ttttagggac atttttacaa atctctatcg tatctattgg gtggcttgtt ctttacagtg
     1681 gtttgtttga agcaggagtt ttccttcttg ctaataaagg ggtggcggta aaaatcaagg
     1741 aagtagatat tcgaaatcgc tttaaattta tttttggaaa aaccttatgg tttcaaattc
     1801 ttttgctcat ctttttgata atcaaacttt atcttggttt ggatgcgagg ttgattttat
     1861 tctatggaca tattttcatt gtctttaatg ccttaatgta tctattatct agtagtcagg
     1921 ttagccttaa aaaaaacaaa ctgtcttctt aatcttacag cagtagagcc tgacaaggtg
     1981 aggtcatagt agggaggatt tctatgaaaa agtatcaact tctattcaaa ataagtgcag
     2041 tcttctctta cttatttttc gtatttggtc tttctcagct gacgcttatc gtccaaaact
     2101 attggcaatt ttcttctcag ataggcaatt tattctggat tcaaaatatc ttgagtttac
     2161 tttttattgg agtcatgatt gtggttcttg ttaagacagg ccatggttat ctcttccgca
     2221 ttccaagaaa aaaatggctt tggtattcga ttttgacagt attagtggta gtgttccaga
     2281 tctcttttaa cgttcagaca gctaaacatg ttcagtcaac tgcggaaggt tgggctgtat
     2341 tgattggtta tagtgggact aactttgcag agctaggtat ttatatagcc ctgttctttc
     2401 tggttccact gatggaagaa ttgatttata gaggattact gcaacatgct ttctttaagc
     2461 attcgcgatt tggtcttgat ttgcttcttc cttctatttt atttgctctc cctcattttt
     2521 caagcctgcc tagtctgtta gatatcttcg tctttgcaac agttggaatc atctttgctg
     2581 gtttgacccg ctataccaag agcatttatc catcctatgc ggtgcatgtg atcaataata
     2641 ttgtagcgac cttcccgttt ttgctcactt ttctacatag ggtcttgggg taaaaaaaca
     2701 aaaggcttgc ttttcagcca tagaggaggt catcatgtat aaacacttat ttttcctaga
     2761 ttccaaaact ttagatcggt tgacacccta tattctagtc ttggcttctg acaccattgc
     2821 ttttaatgtt tttgtgctaa cctttgtatc tgcggtggtt tttaatttcc taaattccat
     2881 gctagcttta atggctatat tcataggggc tggctatgtg gtcggatttt ggttactaat
     2941 actcaatgaa aatcaaagag caaactagga aactagccgc aggctgtact tgagtacggc
     3001 aaggcgacgt tgacgtggtt tgaatttgat tttcgaagag tataaaatgg tttgttttgg
     3061 aaaggctaga actaaagaat gacgtgtagg aagtctgttt gttgaggagg ataattttat
     3121 ggagtttttt gataaatttc atgccttgtg ttttggattt ttagtactaa taattgtcat
     3181 tacagttcct tatacgatta accatggggg tttttttcaa aatgaatctg cattgattct
     3241 tgtaagtctt cttgtaacct cgctgagtgt tgcttatgct agaaagtttg aaatgatttc
     3301 ttttgggatg ttaagcaaga aacaactttt gcttttcatt gcaatctttc ttctaagtgt
     3361 acttgagacg ctggtttata ttcatttctt cgctgtttct tctggctcag gggtccaaca
     3421 cttggcggaa gtcagcagag gaatttccct gtctttgatt ttaactacct cagtttttgg
     3481 ccccatccag gaggaactca ttttcagagg acttcttcaa ggtgcggttt ttgacaattc
     3541 ttggttaggg cttgtgctaa cttcctctct cttttctttc atgcatggac cttctaatgt
     3601 cccttcgttt attttttatc tacttggggg tttgttgctg ggctttgctt ataaaaagag
     3661 tcaaaaccta tgggtttcta ctctagtcca tatgctttac aacagttggc cactcttata
     3721 ttatttataa aaattatgaa aaggtaagca gaagacggtg cttacctttt tcaagctata
     3781 atgataccca agccaatcca gaggcttttc tttgagaatc gggttagagt ggttgacgaa
     3841 taggccaaaa actagtagaa tagtaaggaa actttatacg gaggaaagaa atggatttgg
     3901 gtgataatga gctaacactg actcccatac ctgggaaaag tggcaaggct tatatgggta
     3961 gctatcctga tgggaagcgc atctttgtaa aaatgaacac ctctccaatc ctacctggtc
     4021 tagctagaga acaaattgct ccacaattat tatggagtcg tcgtttggca gatgggcgtg
     4081 atatgtgtgc tcaagaatgg ttgacaggca agatattgac cccctatgat atgaatcgta
     4141 agcaaatcgt caatatttta acccgtcttc atcgctcacg tccgttgatg acacaattga
     4201 gtcgtttggg ctatgccatg gaaacacctg tagatttact acagtcttgg caggaaacgg
     4261 ctccagatgc tttgcgtaaa aatcatttta tcagtgaagt gatggctgat ttacgtcaga
     4321 ctattccagg atttagagag gaccatgcga ccattgtcca tggagatgta cgacatagta
     4381 attggattga gacagatagt ggcttgattt atttagtaga ttgggattcg gttcgcttga
     4441 ccgatcgcat gtttgatgtg gcccatatgc tctgccatta tatttcagaa catcagtgga
     4501 aggaatggtt gacctactac ggttacaagt acaatcaaac ggtattaagt aaattgtatt
     4561 ggtatggtca attgtcttat ttgagtcaga tttccaagta ttatatgaac caagatttag
     4621 aaaatgtcaa tcgggagatt catggtttgc gtcatttccg agacaagtat ggaaagagaa
     4681 gatgagagtt agaaatcgta aaggggcaac agaattacta gaggcaaatc cccagtatgt
     4741 ggtcctcaat cccttggaag ccaaggcaaa atggcgggac ttgtttggca atgataatcc
     4801 cattcatgtg gaagttggaa gtggaaaggg tgcctttgtt tcaggtatgg ccaagcaaaa
     4861 ccctgacatc aactatatcg ggattgatat tcaaaagtct gttttgagct acgctttgga
     4921 caaggtgctt gaagctggag tgtctaacat caagctcttg tgggtagatg gttctgactt
     4981 gactgactac tttgaagacg gtgagattga tcgcttgtat ctgaactttt cagatccatg
     5041 gccgaaaaaa cgccatgaaa agcgtcgttt gacctacaag acctttttgg ataccttcaa
     5101 acgtatcttg cctgaaaatg gagaaattca tttcaagacg gataaccgtg gcttgtttga
     5161 gtacagttta gtgagctttt ctcaatatgg catgaaactc aatggtgtct ggctagattt
     5221 gcatgccagt gattttgaag gcaatgtcat gacagaatac gagcaaaaat tctcaaacaa
     5281 ggggcaagtt atctaccgag ttgaggcaga attttaagag atagcctaaa attaggctgt
     5341 acaagtgctt ttgctttaca taagttggca aacgtgctat actgatagta agaatatgaa
     5401 aagtgaggcg gggaaatatc ttcgcctctt gcttatgagg aggtggacgc aatcgcaaca
     5461 atcgtagaat tagtcagaga agttgtagaa cctgtcatag aagctccttt tgaactcgtg
     5521 gatatcgagt atggaaagat tggcagtgac atgattctca gtatttttgt agataaaccc
     5581 gaaggaatta ccttgaacga cacggcagac ttgacagaaa tgatcagtcc tgtcctagac
     5641 accatcaagc cagatccctt cccagaacaa tatttcctag aaattaccag tccaggtttg
     5701 gaacgtcctt tgaaaaccaa ggatgccgtc gctggagcgg ttggaaaata catccatgtc
     5761 gggctctacc aagccatcga taagcaaaag gtctttgaag gaaccttgtt ggccttcgaa
     5821 gaggacgagt tgactatgga atatatggac aagacgcgta agaaaaccgt ccaaattcca
     5881 tacagtttag tatcaaaagc acgtttagca gttaaattat agaaaaagaa aggatagctt
     5941 ttgaggattc aaaagtgaag aaaacatgag taaagaaatg ctagaggcct tccgcatttt
     6001 ggaagaagac aagggaatca aaaaagaaga tatcatcgac gcagtagtag agtcgcttcg
     6061 ttccgcttat cgcagacgct atggtcagtc agacagcgta gctattgact tcaacgaaaa
     6121 aacaggtgac tttacagttt atactgtccg tgaagttgtt gatgaagtat ttgatagccg
     6181 tttggaaatc agcttgaaag atgctcttgc cattaattca gcttatgaac ttggagacaa
     6241 aatcaagttt gaagaagcac cagctgagtt tggtcgtgta gcagcccaat ctgccaaaca
     6301 aaccatcatg gaaaaaatgc gcaagcaaac acgtgccatc acttacaata cttacaaaga
     6361 acatgagcaa gaaatcatgt ctggtacagt agaacgcttt gacaaccgct ttatctatgt
     6421 caaccttggt agcatcgaag cccaattgtc aaaacaagac caaattcctg gagaagtttt
     6481 tgcttctcat gatcgtatcg aagtttatgt ttacaaggtt gaagacaacc ctcgtggtgt
     6541 gaacgtcttt gttagccgta gccatccaga aatgatcaaa cgtttgatgg agcaagaaat
     6601 tccagaagtt tatgatggaa ctgttgaaat catgagcgtg gctcgtgaag caggtgaccg
     6661 tacgaaggtt gctgttcgta gtcacaatcc aaacgtggat gctatcggta caatcgttgg
     6721 acgtggtggt gctaatatca agaagattac tagcaaattc cacccagctc gttacgatgc
     6781 taaaaatgac cgcatggtac caatcgaaga aaatatcgat gttatcgagt gggtagcaga
     6841 tccagctgaa tttatctaca atgccatcgc tcctgctgag gttgaccaag ttatctttga
     6901 tgaaaacgac agcaaacgtg ccttggtggt tgttccagat aacaagcttt ctcttgccat
     6961 tggtcgtcgt ggacaaaacg tgcgcttggc ggctcacttg actggttacc gtatcgatat
     7021 caagtctgct agcgaatttg aagccatgga agacgctgct tcagtagagt tggaagtaga
     7081 aaacgatact gtagaagaat aaaagctgct agaggaggga aagatgaaaa caagaaaaat
     7141 ccctttgcgc aagtctgttg tgtctaacga agtgattgat aagcgtgatt tgctccgcat
     7201 tgtcaagaac aaggaaggac aagtctttat tgatcctacg ggcaaggcca atggccgcgg
     7261 cgcttatatc aaactagaca atgcagaagc cctagaggcg aaaaagaaga aggtctttaa
     7321 ccgcagcttt agcatggaag tggaagaaag cttttatgac gagttgatcg cttatgtgga
     7381 tcacaaagtg aaaagaagag agttgggact tgaataagca aaagataagt aatctcttgg
     7441 ggcttgctca gcgagcaggg cgcatcatat cgggtgaaga attggtggtc aaggccattc
     7501 aagacggcaa ggccaagttg gtctttctag ctcatgatgc tggacccaat ctggccaaga
     7561 agattcaaga taaaagtcat tattatcaag tagaaattgt aaccgtgttt tcaacactgg
     7621 aattaagcat agcagtcggg aaatcgagaa aggttttggc tgtaacagat gctggattta
     7681 caaagaaaat gaggtctctt atggaataga agaggaggac atgatttgtc taagaaaaga
     7741 ttgtacgaaa tcgcaaaaga acttggaaaa gaaagtaaag aagttgtagc gcgtgcaaaa
     7801 gagttaggct tggatgtgaa aagccactca tcaagtgtgg aagaagctgt cgctgcaaaa
     7861 attgctgcca gctttaagcc tgcagctgct ccgaaagtag aagcaaaacc tgcagcacca
     7921 aaagtaagtg cagaaaagaa agccgaaaaa tctgagacag ctaaaccagc tgtagctaag
     7981 gaagaggcaa aaccggctga gccagttgct ccgaaaacag aaaaagtagc agtgaaaccg
     8041 caaagtcgta atttcaaggc tgagcgtgaa gcccgtgcta aagagcaggc agaacgacgc
     8101 aagcaaaata agggcaataa ccgtgaccaa caacaaaacg gaaaccgtca gaaaaacgac
     8161 ggccgtaatg gtggaaaaca aggtcaaagc aaccgcgaca atcgtcgctt taatgaccaa
     8221 gctaagaagc agcaaggtca gcaaaaacgt agaaatgagc gccgtcagca agaggacaaa
     8281 cgttcaaatc aagcggctcc acgtattgac tttaaagccc gtgcagcagc cctaaaagca
     8341 gagcaaaatg cagagtacgc tcgttcaagt gaggaacgct tcaagcagta tcaggctgct
     8401 aaagaagcct tggctcaagc taacaaacgc aaggaaccag aggaaatctt tgaagaagcg
     8461 gctaagttag ctgaacaagc acagcaagtt caagcagtgg ttgaagtcgt ccctgagaaa
     8521 aaagaacctg cagtggatac acgtcgtaaa aaacaagctc gaccagacaa aaatcgtgac
     8581 gattatgatc atgaagaaga tggtcctaga aaacaacaaa agaatcgaag tagtcaaaat
     8641 caagtgagaa atcaaaagaa tagtaactgg aataacaaca aaaagaacaa aaaaggcaat
     8701 aacaagaaca accgtaatca gactccaaaa cctgttacgg agcgtaaatt ccatgaattg
     8761 ccaacagaat ttgaatatac agatggtatg accgttgcgg aaatcgcaaa acgtatcaaa
     8821 cgtgaaccag ctgaaattgt taagaaactt ttcatgatgg gtgtcatggc cacacaaaac
     8881 caatccttgg atggggaaac aattgaactc ctcatggtgg attacggtat cgaagcaaaa
     8941 caaaaggttg aagtggataa tgctgacatc gaacgtttct ttgtcgaaga tggttatctc
     9001 aatgaagatg aattggttga gcgtccacca gttgttacta tcatgggaca cgttgaccac
     9061 ggtaaaacaa cccttttgga tactcttcgt aactcacgtg ttgcgacagg tgaagcaggt
     9121 ggtattactc agcatatcgg tgcctaccaa atcgtggaaa atggtaagaa gattaccttc
     9181 cttgatacac caggacacgc ggcctttaca tcaatgcgtg cgcgtggtgc ttctgttacc
     9241 gatattacga tcttggtcgt agcggcagat gacggggtta tgcctcagac tattgaagcc
     9301 atcaaccact caaaagcagc taacgttcca atcatcgtag ccattaacaa gattgataaa
     9361 ccaggtgcta acccagaacg cgttatcggt gaattggcag agcatggtgt gatgtcaacc
     9421 gcttggggtg gagattctga atttgttgaa atctcagcta aattcaacca aaatatcgaa
     9481 gaattgttgg aaacagtcct tcttgtagct gaaatccaag aactcaaggc agacccaaca
     9541 gtgcgtgcaa tcggtacggt tatcgaagcg cgcttggata aaggaaaagg tgcggtcgca
     9601 acccttcttg tacaacaagg taccttgaat gttcaagacc caatcgttgt cggaaatacc
     9661 ttcggtcgtg tccgtgctat gaccaacgac cttggtcgtc gtgttaaagt tgctggacca
     9721 tcaacaccag tctctatcac aggtttgaac gaagcaccga tggcgggtga ccactttgcc
     9781 gtttacgagg atgaaaaatc tgcgcgtgca gcaggtgaag agcgtgccaa acgtgccctc
     9841 atgaaacaac gtcaagctac ccaacgtgtt agccttgaaa acctctttga tacccttaaa
     9901 gctggggaac tcaaatctgt taatgttatc atcaaggctg atgtacaagg ttctgttgaa
     9961 gccctttctg cctcacttca aaagattgac gtggaaggtg tcaaagtgac tatcgtccac
    10021 tcagcggtcg gtgctatcaa cgaatcagac gtgacccttg ccgaagcttc aaatgccttt
    10081 atcgttggtt tcaacgtacg ccctacacca caagctcgtc aacaagcaga agctgacgat
    10141 gtggaaatcc gtcttcacag cattatctac aaggttatcg aagagatgga agaagctatg
    10201 aaagggatgc ttgatccaga atttgaagaa aaagttattg gtgaagcggt tatccgtgaa
    10261 accttcaagg tgtctaaagt gggaactatc ggtggattta tggttatcaa cggtaaggtt
    10321 gcccgtgact ctaaagtccg tgttatccgt gatggtgtcg ttatctatga tggtgaactc
    10381 gcaagcttga aacactataa agacgacgtg aaagaagtga caaacggtcg tgaaggtgga
    10441 ttgatgatcg acggctacaa tgatattaag atggatgatg tgattgaggc gtatgtcatg
    10501 gaagaaatca agagataaga ttttttgctc ctttcttagg tggtgaggga cgcaagcaaa
    10561 ccgatggttt cattgcttat ttttgagcct agggtctcaa aaatcccctg tgatgggact
    10621 gataaatcag ttccatcact ttcaccacgg cgaaagaagc agatgacttc aaattgaact
    10681 tcgtttcaat ttaaactgaa aatcaagaag tttaaaatag ctaggtctgc tggcctagct
    10741 tttggttcaa agtagagaaa ggaatatcat ggcaaatcat ttccgtacag atcgtgtggg
    10801 catggaaatc aagcgtgaag tcaatgagat tttgcaaaag aaagtccgtg atccacgtgt
    10861 ccaaggtgtg accatcacag atgttcagat gctgggtgac ttgtctgttg ccaaggttta
    10921 ttacaccatt ttgagtaacc ttgcttcgga taaccaaaaa gcccaaatcg ggcttgaaaa
    10981 agcaactggt accatcaaac gtgaacttgg tcgcaatttg aaattgtaca aaatcccaga
    11041 tttgaccttc gtcaaagacg agtccatcga gtatggaaac aagattgacg agatgctacg
    11101 caatctggat aagaactaaa gaagaggggt tgcccctctt ttttggtgga ggaaaatagg
    11161 ttgaatttga aatggaaaaa tattctttta aaatatattg aaactagaat agtac
//
LOCUS       DAVLTT010000059        10995 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLTT010000059 DAVLTT010000000
VERSION     DAVLTT010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10995
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.059"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            125..700
                     /locus_tag="VYN15_001722"
     CDS             125..700
                     /locus_tag="VYN15_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEV1453011.1"
                     /translation="MKTIVKICLVALSAFLLLFAGKNVFADSNSHDNLNSLEVSDRSF
                     RNGELLKSYLVKDKDRIYFDYDKAVQDKQAKDVIDMGLLVETISEDYSSNTFTPAKYF
                     KAGLPVHGNYCGPGYNGEGFTLPVVDVLDQGCQNHDRCYKWGAGIGANCECNRQLVDF
                     IKVNRRWIPESALWVADAIRVYFETIGAIGC"
     gene            694..981
                     /locus_tag="VYN15_001723"
     CDS             694..981
                     /locus_tag="VYN15_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453012.1"
                     /translation="MLNLKSFITRYSKVYIGLVLLIWIAFFFLPWGSPILGGKIDLFS
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFILFAILPILGN"
     gene            1127..3640
                     /gene="secA"
                     /locus_tag="VYN15_001724"
     CDS             1127..3640
                     /gene="secA"
                     /locus_tag="VYN15_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV1453013.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            3721..4752
                     /locus_tag="VYN15_001725"
     CDS             3721..4752
                     /locus_tag="VYN15_001725"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1453014.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYMEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            4754..5785
                     /locus_tag="VYN15_001726"
     CDS             4754..5785
                     /locus_tag="VYN15_001726"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1453015.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            5824..6192
                     /locus_tag="VYN15_001727"
     CDS             5824..6192
                     /locus_tag="VYN15_001727"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV1453016.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            6182..7285
                     /locus_tag="VYN15_001728"
     CDS             6182..7285
                     /locus_tag="VYN15_001728"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV1453017.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            7304..9319
                     /gene="recG"
                     /locus_tag="VYN15_001729"
     CDS             7304..9319
                     /gene="recG"
                     /locus_tag="VYN15_001729"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV1453018.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLALLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            9635..10615
                     /locus_tag="VYN15_001730"
     CDS             9635..10615
                     /locus_tag="VYN15_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV1453019.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT         3187 a         2102 c         2595 g         3111 t
ORIGIN      
        1 aaactcattt gacaagcttt aagtttatgt gtatttagta catttaccaa aaattaactt
       61 tcttttggta aaaatattgt ttgtgtattt agcttataac ttatgtttat taggaggagt
      121 agtcatgaaa actatcgtta aaatttgttt agttgcttta tctgcctttt tacttttatt
      181 tgctggaaaa aatgtttttg cagactctaa ttcacatgat aacttaaact ctttggaagt
      241 tagcgataga agttttcgta acggagaatt gttgaagagt tatcttgtaa aagataaaga
      301 taggatttat tttgattatg ataaagcggt tcaagataaa caagcgaaag atgtaattga
      361 catgggttta ttggtagaga caataagcga agactatagt tcaaatacgt ttacacctgc
      421 taaatatttt aaggcaggat tgcctgttca cgggaattac tgtggtcctg gttacaacgg
      481 ggaaggattt actttacctg tggtagacgt tttggatcaa ggttgccaaa atcatgatag
      541 atgttacaag tggggagctg gtattggagc taattgtgag tgtaatcgtc agttagtcga
      601 ttttataaaa gttaacagac gttggatacc agaaagtgcc ttatgggttg cggatgctat
      661 cagagtttat tttgaaacga ttggagctat aggatgttga atctaaaatc atttattaca
      721 cgctattcta aggtctatat tggtttagtt ctgttgatct ggattgcttt cttctttctt
      781 ccttggggca gtccgattct gggggggaag attgacctct tcagcataca gaaagtcttg
      841 ctagtttttg gcattctgtc cattttgatg gccttgctgt ccaagaaagt cagtctcttt
      901 gtttttggat tgatctgctg tctttctctt tggattaact tatttatcct atttgctatt
      961 ttgccgattc ttggcaatta aagtatcata aaagtcagag aggttagctt ggaaactaac
     1021 ctctttttcc ttttcaaaat ggggattctt ccttgaaaat aatcagtaat tgtgctaaaa
     1081 ttaaaggaac attctaaaat attcggaatt taaagtaagg aaaaacatgg ctaatatttt
     1141 aaaaacaatt atcgaaaatg ataaaggaga aatccgtcgt ctggaaaaga tggctgacaa
     1201 ggttttcaaa tacgaagacc aaatggctgc tttgactgac gaccaactaa aagcaaaaac
     1261 agttgaattt aaggaacgtt atcaaaatgg agaatcactg gattcattgc tttacgaagc
     1321 atttgcggtt gtccgtgaag gtgccaaacg tgtcctaggt ctcttccctt ataaggttca
     1381 ggtcatgggg gggattgttc ttcaccatgg tgacgtgcca gagatgcgta caggggaagg
     1441 gaaaaccttg actgcgacca tgccggtata cctcaatgcc ctttcaggta aaggggttca
     1501 cgtagttacg gttaatgaat acctgtcaga acgtgacgcg actgagatgg gtgaattgta
     1561 ctcttggctt ggtttgtcag tagggattaa cttggctacc aaatctccaa tggagaaaaa
     1621 agaagcctat gagtgtgata ttacttactc aactaactca gaaatcggat ttgactacct
     1681 tcgtgacaac atggtcgttc gcgctgaaaa catggtacaa cgtccgctta actatgcctt
     1741 ggtcgatgag gttgactcta tcttgattga cgaggctcgt acacctttga ttgtatcagg
     1801 tgccaatgcg gttgaaacca gtcagttgta tcacatggca gaccactatg taaaatcttt
     1861 gaacaaagat gactacatca tcgatgtgca gtctaagact attggtttgt ctgattcagg
     1921 gattgacagg gctgaaagct acttcaaact tgaaaacctc tatgacatcg aaaacgtggc
     1981 tttgactcac tttatcgata acgcccttcg tgccaactac atcatgcttc tcgatattga
     2041 ctatgtggtg agcgaagagc aagaaatctt gattgtcgac caatttacag gtcgtaccat
     2101 ggaaggtcgt cgttattctg atggattgca ccaagctatt gaagccaaag aaggtgtgcc
     2161 aatccaggat gaaaccaaga catctgcctc aatcacgtac caaaaccttt tccgtatgta
     2221 caaaaaattg tctggtatga cgggtacagg taagactgag gaagaagaat ttcgtgaaat
     2281 ctacaacatt cgtgttattc caatcccaac aaaccgtcct gttcaacgta ttgaccactc
     2341 agaccttctt tatgcaagta tcgaatctaa gtttaaagcg gttgtcgaag acgttaaggc
     2401 tcgttaccaa aagggtcaac ctgtcttggt tggtacagta gcggttgaaa ctagtgacta
     2461 catttctaag aaattggttg cagctggtgt tcctcacgaa gtcttgaatg ccaaaaacca
     2521 ctatagagaa gcccaaatca tcatgaatgc tggtcaacgt ggtgccgtta ccatcgcaac
     2581 caacatggcg ggtcgtggta ccgacatcaa gcttggtgaa ggtgttcgtg aacttggagg
     2641 actttgtgtt attggtacag aacgtcatga aagtcgtcgt atcgataacc agcttcgtgg
     2701 acgttcaggt cgtcaaggag atccaggtga gtcacaattc tacctatctc ttgaagatga
     2761 tttgatgaaa cgttttggtt ctgaacgctt gaagggaatc tttgaacgtc tcaacatgtc
     2821 tgaagaggcg attgagtctc gcatgttgac gcgtcaggtt gaagcagctc agaaacgtgt
     2881 cgaaggaaat aactacgata cccgtaaaca agtccttcaa tacgatgatg tcatgcgtga
     2941 acaacgtgag attatctatg ctcaacgtta cgatgtcatc actgcagatc gtgacttggc
     3001 acctgaaatt cagtctatga tcaaacgcac gattgaacgt gtcgttgatg gtcatgcgcg
     3061 tgccaaacaa gatgaaaaac tagaggcaat tttgaacttt gctaagtaca acttgcttcc
     3121 tgaagattct attacgatgg aagacttgtc aggcttgtct gataaggcca tcaaggaaga
     3181 gcttttccaa cgtgccttga aggtttacga tagtcaggtt tcaaaactac gcgatgaaga
     3241 agcagttaaa gaattccaaa aagttttgat tctacgagtg gtggataaca agtggacaga
     3301 tcatatcgat gcccttgatc aattgcgtaa cgcggttgga cttcgtggct atgctcagaa
     3361 caaccctgtt gttgagtatc aggcagaagg tttccgtatg tttaatgata tgattggttc
     3421 gattgagttt gatgtgacac gcttgatgat gaaagcacaa attcatgaac aagaaagacc
     3481 acaggcagaa cgtcatatca gtacaacagc gactcgcaat atcgctgctc accaagcaag
     3541 tatgccagaa gatttggatt tgagccagat tggacgcaat gaactttgcc catgtggttc
     3601 tggtaagaaa tttaaaaact gtcacggtaa aagacaataa aatgagatag tttagaggcg
     3661 gatatcttgt gaaaagtaaa tttttactgg gtatccgttt gctttataag gagatgagtt
     3721 atggtattta cagcaaaaag ctctaaaata aatatagaag aagttcgtgc cttgtcaaaa
     3781 ttagaaggtc aggctttgga gaggaaatca cagcgagatc aagagctaga agccattata
     3841 cgtggagaag accagcgaat tctcttggta atcgggccat gctcatctga caacgaagaa
     3901 gctgtccttg aatacgctaa gcgtttggca gtcctacaag aagaagtggc agatcgtatc
     3961 tttatggtta tgcgtgttta tactgccaaa ccccgtacca acggagatgg ctataagggc
     4021 ttgattcacc agcctaacgc gacagaagcg cctagtctta tcaatggaat caaagccgtt
     4081 cgccatcttc actatcgtgt catcacagaa acagggatga caactgctga tgaaatgctt
     4141 tatcctgaaa accttccgct tgtagatgat ttgatttctt acatggcagt tggtgcccgt
     4201 tcagttgaag accagcaaca ccgctttgtg gcaagtgggg caggattttc tactggtttt
     4261 aaaaatccaa cctctggaaa tctcaatgtc atgtttaatg ggatttatgc tgctcaaaac
     4321 aaacaaagtt tccttttctt aggaaaagaa gtagaaacaa ctgggaaccc gctttcacac
     4381 gctattcttc gtggtgctct taatgagtat ggaaaaaata ttcccaacta ctattatgac
     4441 aatttaattg ataccattgc ccagtatgag aaaatgggct tggaaaatcc ttttatcatc
     4501 attgatacca atcatgacaa ttctggtaag cagtatatgg aacagatccg aattgtccgc
     4561 cagaccttga ttaaccgtgc ttggaatgaa aaaattaagc agttcgttcg tggttttatg
     4621 attgagtctt atctggaaga tggtcgacaa aatgagccag aagtatttgg taagtctatc
     4681 acagaccctt gcctgggttg ggataacaca gaagctcttg tcagagaaat ttacaaaacg
     4741 ttaggagaat aagatggcat ttattgaaaa aggtcaagaa atcgatatgg aagtcatcaa
     4801 ggctgaaacc caattgtctg cagaagcctt gagactcaag gaaagccgtg acagggaatt
     4861 ggcagatatt atttcagggg aagatgaccg tattctcttg gtgattggtc cttgctcttc
     4921 tgataatgaa gaggcggtct tggaatatgc tcgccgttta tccgccttgc aaaagaaggt
     4981 agcggacaag attttcatgg tcatgcgcgt gtatactgct aagcctcgta ccaatggaga
     5041 cggctataaa ggattggttc accagccaga tacttctaag gctccaagcc tgattaacgg
     5101 cttgcaggct gtgcgccagt tgcactaccg cgtgattaca gagactggtt tgacaacggc
     5161 agatgagatg ctttatccgt caaatctgat cttggtggat gacttggtca gctaccatgc
     5221 cgttggagct cgttctgtgg aagaccaaga gcaccgcttt gtggcttctg ggattgatgc
     5281 accagtaggg atgaaaaatc caacctcagg aaatttgggt gttatgttta acgccatcta
     5341 tgctgctcaa aacaagcaaa ccttccttta tcatgggcag gaagttgaga catcaggtaa
     5401 tcctttggcc catgttatcc tccgtggagc agtcaacgag tatggcaatt atatgccgaa
     5461 ttactactat gaaaacctac tccaagccat tgaacgctat gaaaccatgg gacttgaaaa
     5521 tccttttatc ctcattgaca ccaaccatga taactcaggc aagcaatata tggagcagat
     5581 tcgaattgtt cgccagacat tgcagaatcg tgattggaat gagaaaatta aaaagacggt
     5641 tcgaggattt atgattgaat cttacctagc agatggtcgt caaaaccaac cagagatctt
     5701 tggttgctct attactgacc cttgcctagg ttgggaaaat acagaggcct tggtagaaga
     5761 gatttatgtt accttgacaa aataagtgaa aaggatggag ttggggaatc tcaactcctt
     5821 ttgatgagaa tgatagttgg acacggaatt gacatcgaag aattggcttc gatagaaagc
     5881 gcagttacac gacatgaagg atttgctaag cgtgtactga ccgctcagga aatggagcgc
     5941 ttcaccagtc tcaaaggacg caggcaaata gaatatttag ctggtcgctg gtcggctaag
     6001 gaggcctttt ccaaggctat gggaacgggc attagcaagc tcggttttca ggatttggaa
     6061 gtcttgaaca atgaacgtgg ggcgccttat tttagtcagg caccattttc aggaaagatt
     6121 tggctgtcta tcagccacac cgatcagttt gtgacagcca gtgtcatttt ggaggaaaat
     6181 catgaaagct agtccacata gaccaaccaa ggctctgatt catctgggag ctattcgaca
     6241 aaatattcag caaatggggg ctcatatccc tcaaggaacg ctcaagttgg ctgtggtcaa
     6301 ggccaatgct tatggtcatg gagctgttgc cgttgccaag gcaattcaag atgatgttga
     6361 tggtttttgc gtttccaata tcgatgaagc cattgaactc agacaagctg gactcagcaa
     6421 gccaatcctc attttaggag tttctgaaat cgaagctgtt gctctagcta aagaatatga
     6481 cttcaccttg acagtggctg gactggagtg gattcaagca ctcttagata aggaagtgga
     6541 cctaactgga ttgacagtcc acctcaagat tgattcaggg atgggacgga ttggttttag
     6601 agaggccagt gaggttgagc aggctcaaga tttgctacaa caacacggtg ttcgtgttga
     6661 aggaatcttt acccactttg ctactgctga tgaggaatca gatgactatt ttaatgccca
     6721 gttagaacgg tttaaaacta ttttagctag tatgaaggaa gttccagagc tggttcatgc
     6781 tagcaattct gcaacgactc tttggcatgt agagactatt ttcaatgcgg ttcgtatggg
     6841 agatgccatg tatggcctca atccaagtgg agcggtcttg gatttgcctt atgatttgat
     6901 accggccttg accttggagt ctgctctggt tcatgtcaag acagttccag ctggagcttg
     6961 catgggctat ggagcaactt atcaagcgga tagcgagcaa gtcatcgcga ccgtgccaat
     7021 cgggtatgca gatggatgga caagagacat gcaaaatttc tctgtcttgg tagatggcca
     7081 agcttgccca attgtcggca gggtttcgat ggaccaaatc actattcgat tgcctaagct
     7141 ttatccgcta ggaaccaagg taaccttgat tggctccaat ggggataagg aaatcactgc
     7201 aactcaggta gcgacctacc gcgtcaccat taactatgag gtggtttgcc tcctcagcga
     7261 ccgtattccg agagaatatt attagaaaag aaaggagtgg agcatgaatc tacatcaacc
     7321 cttgcatgtc ttgcctggtg tgggaccaaa gtcagcagaa aaatacgcca aactaggaat
     7381 tgaaaacttg caagatctct tgctctactt tcctttccgt tatgaagact tcaaaaccaa
     7441 gcaggtgctg gaactagaag acggtgagaa ggcagttctt tctggtcagg tagtgactcc
     7501 tgctagtgtc cagtattatg gtttcaagcg caatcgcctg cgttttagtc tcaagcaggg
     7561 agaggtcgtt tttgcggtga atttctttaa ccagccctat ctggctgata aaatagagtt
     7621 gggagcaact cttgctgtct ttggaaaatg ggaccgcgct aaggctagtc tgactgggat
     7681 gaaggttctg gctcaggtag aagatgacct ccagcctgtc tatcgtctgg ctcagggaat
     7741 cagtcaggcc agtctggtta aggtcatcaa gacggctttt gatcagggac tagccctctt
     7801 gatagaagaa aatctgcccc agtctttact agacaaatac aaactcatgt cccgttgtca
     7861 ggcagtccga gctatgcatt ttccaaagga tttggcagaa tacaagcagg ctcttcgccg
     7921 tataaagttt gaggaactct tttatttcca aatgcagctg cagatgctca agtctgaaaa
     7981 tagagttcag ggaagtggtc tggttctgaa ttggtctcag gaaaaagtga cagcagttaa
     8041 agtaagtctt ccttttgccc tgacccaagc tcaggaaaag agtttgcagg aaattttaac
     8101 tgatatgaag tccgaccacc acatgaatcg tctcctacaa ggggatgtgg ggagtggaaa
     8161 aacggtagtc gctggcttgg ccatgtttgc ggcagtgaca gcaggttatc aggctgccct
     8221 aatggtacca acagaaatcc tcgcagagca acactttgag agtttacaga acctttttcc
     8281 caatttgaaa ctggctctct tgacaggttc cttgaaagct gcagaaaaga gagaggtctt
     8341 ggagaccatt gccaagggtg aggctgattt gattatcgga actcacgctc tgatacaaga
     8401 tggggtggag tatgctcgtc ttggtttgat tattatcgat gagcagcacc gttttggtgt
     8461 agggcaaagg cgtattttac gggaaaaagg tgacaatcca gatgtcctca tgatgacggc
     8521 gactcccatt ccacggacgc ttgccatcac agcctttgga gatatggatg tttccattat
     8581 cgaccagatg ccagcaggtc ggaagcctat tgtgacgcgc tggatcaaac atgagcaact
     8641 acctcaggtc ttgacttggt tagaggggga aattcaaaaa ggttcccaag cctatgtcat
     8701 ctctcctttg attgaagaat cagaagctct agatttgaaa aatgccattg ccttatcaga
     8761 ggagttgacg actcattttg caggcaaggc agaggtggct cttctacatg gtaggatgaa
     8821 gagtgacgaa aaagaccaga tcatgcagga tttcaaggag agaaagacgg atattctggt
     8881 ttcgacgacg gttattgagg ttggggtcaa cgttcccaat gcgactgtca tgattatcat
     8941 ggatgccgat cgcttcggtc tcagtcaact tcaccagctt agaggtcgtg tcggtcgggg
     9001 ggacaagcag tcctacgctg ttctcgttgc caatcccaag acggattctg ggaaagaccg
     9061 catgcgcatc atgacagaaa cgaccaatgg atttgtcctt gcggaggaag atttgaaaat
     9121 gcgtggttct ggtgagattt ttggaaccag acagtcagga cttccagagt tccaagtggc
     9181 tgatattatc gaagattttc cgattttaga agaagcaaga aaggttgcta gctacattag
     9241 ttctatagaa gcttggcaag aagatccaga gtggcgcatg attgcccttc atctggaaaa
     9301 gaaagaacat ctggattaag ctttctctaa ggaaaactta agctagtttt taggtttggc
     9361 tcttatacta aagtcatcaa aaagaaacga ggactctcat atgacagtaa cgattaaagt
     9421 aaattaccaa accactttcc aaaagaagga agcaaaaaac tagtataaac agaagagaga
     9481 gcgaaatgct ctttttcgtt tctaaaacta ctttcagccc atcatcctaa aagtaaagaa
     9541 tctaaattca ctttctattt atccttcttt cttgcattga ttacatagat atgctacagt
     9601 tgtggtaacg attacaaaat aaaaggagca tgctatgaaa aatccagctt tgctagaaga
     9661 aattaagacc tatagaggaa gggatgaggt tccggaagac tttgatgctt tctgggatgg
     9721 ggaagtgaaa aatgtttcca cgcttccatc ctaccacttg gaggaaagag atttccacat
     9781 tcctcaagtc aagtgctatg agttaacatt tgaaggaagc aaggaaggaa aggtctatgc
     9841 acgcattgtt cttccaaaga gtgaggagaa ggttccacta atcttccatt ttcatggtta
     9901 tatgggacgt ggctgggact gggccgacat gctgggcttc accgtagctg gttacggtgt
     9961 tgtttccatg gatgtgcggg gtcagtcagg ttactcacaa gacggcttgc gttctccttt
    10021 aggaaatacc gtgaaggggc atattatccg tggtgctgtg gaaggtcggg accacctctt
    10081 ttataaggat gtttatctgg atatttacca gttggtcgaa attgttgcta gtctgtctca
    10141 ggttgatgag aagcgtcttt ctagctatgg tgcctcacaa ggaggggctc tagctctagt
    10201 tgcagcagcg ctcaatcctc gaattcagaa aacagttgcc atttatccct tcttgtcaga
    10261 cttcagacgg gtgattgaga ttggtaatac tagcgaggct tacgacgaac ttttccgtta
    10321 tttcaagttt cacgacccct tccatgaaac agaggaggaa atcatggcga cccttgccta
    10381 tatcgatgtc aaaaatcttg cccatcgtat ccaaggtgag gttaagatga ttacgggctt
    10441 ggacgacgat gtttgctatc ccattaccca gtttgcgatt tataatcgtc tgacctgcga
    10501 taaaacctat cgcatcatgc ctgagtatgc tcacgaagcc atgaatgtat ttgtcaatga
    10561 ccaagtctac aactggctct gtggaagtga gattcctttt aaatatctaa aataaggagt
    10621 cgactctaag cacaaaatct taaaaattac aaacacgcat agtatcaggg gattaaaaaa
    10681 acttgatact atgcgtttta tcatggaaat atagtaaaat gaaacaagaa taggacaaaa
    10741 cgatcagggc agtcaaatcg atttctaaca atgttttaga agtagatgtg tactattcta
    10801 gtttcaatct attatattta tagaattttt tgttgctaga tttgtcaaat tgcttaaaat
    10861 aatttttttc agaaagcaaa agccgatacc tatcgagtag ggtagttctt gctatcgtca
    10921 ggcttgtctg taggtgttaa tacttttcaa aaatctcttt aaaccacgtc agcttcgcct
    10981 tgccgtatat atgtt
//
LOCUS       DAVLTT010000060        10889 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLTT010000060 DAVLTT010000000
VERSION     DAVLTT010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10889
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.060"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(202..618)
                     /locus_tag="VYN15_001731"
     CDS             complement(202..618)
                     /locus_tag="VYN15_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1453020.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSVLMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(630..1325)
                     /locus_tag="VYN15_001732"
     CDS             complement(630..1325)
                     /locus_tag="VYN15_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1453021.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGGYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            complement(1519..4020)
                     /locus_tag="VYN15_001733"
     CDS             complement(1519..4020)
                     /locus_tag="VYN15_001733"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV1453022.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNATNKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            complement(4475..5563)
                     /locus_tag="VYN15_001734"
     CDS             complement(4475..5563)
                     /locus_tag="VYN15_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV1453023.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDSYVNSK"
     gene            complement(5581..6249)
                     /locus_tag="VYN15_001735"
     CDS             complement(5581..6249)
                     /locus_tag="VYN15_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV1453024.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            complement(6268..8706)
                     /locus_tag="VYN15_001736"
     CDS             complement(6268..8706)
                     /locus_tag="VYN15_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV1453025.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERAHKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(8857..10155)
                     /locus_tag="VYN15_001737"
     CDS             complement(8857..10155)
                     /locus_tag="VYN15_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1453026.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSWYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLMISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            complement(10172..10480)
                     /locus_tag="VYN15_001738"
     CDS             complement(10172..10480)
                     /locus_tag="VYN15_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1453027.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(10526..10846)
                     /locus_tag="VYN15_001739"
     CDS             complement(10526..10846)
                     /locus_tag="VYN15_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1453028.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
BASE COUNT         3334 a         2365 c         1794 g         3396 t
ORIGIN      
        1 ttctaaaatt ttactatttt gcaaaaaatt tctatcacca gcacctcacc acgcaaaaaa
       61 gccacctgat tgggtggctt cattaggaga ttgtgatgaa aaaagtttag gattttatta
      121 aataaagtta ggaggtcttt atttaatgac tatataatac tagaccatcc ttaaattttg
      181 cttaagaaaa aacaagtttt gttatttttt acgattcatc caagtcatcc ctatacaatt
      241 ataggtggat aagatttcaa agcccataga acgatagaag cccaaggttc tttctgtctc
      301 ttctgtcacc agctggactt gataggcatc tttgtaatcc tctaaagcct ctttcatcaa
      361 gacactacca attccttgac gctgatagat tggtaaaacg attaaatcct gaaccaatac
      421 tgatgagaat ccatctccaa ccaaacgaat caagcccacc acagcatcac catcaagtgc
      481 cagataaatt actaatgaat gagataaggc ctgctccagc atctctggtt gatgggtata
      541 atttgtccaa ccgacagcct gatagagatg taaaacatcc tctagcttga caatttcttg
      601 ctttttaata gtaatcatct caacacctct taaagttctc tcaagctctt gtactgctgt
      661 ccatttttat caaaattttc aggacgcaac catgtttcca aacgatcttt gacttgaggc
      721 cagtccttat caatcataga caaccaatcc gtatctctcg tacgtccctt ataaaccact
      781 gcctgacgga aggttccttc ataaataaag ctcaaacgct ccgcagctcg tctggatggc
      841 agatttaagg catcgcattt ccactcgtag cgacgatagt ttagctcctc aaaaacatag
      901 cgagctagga gatactgagc ttcagttcct atccgtgtac cccttagctc tggagaaaaa
      961 gtgacagctc ccacttctat tactcggtta ttctggtcaa tgcgcatgag agaaaaagat
     1021 cccaaagcct taccagtcgc cttgtctatg attgcatagt aaaaacggtc cttacgagcc
     1081 aacatctgat gtaaaaggct aaccagctcc cccatatctg ctactggctc ctgaaaaagg
     1141 taggtccaca tctcctgagg cgtatcaggc ccataaacag ctagcaaatc ctccgcatgc
     1201 ttttccactg aaagagcctc tatcctagca taaccccctt ctaagaaatc aatagaaggc
     1261 agttcacctg gtgtataacc ttccattgac tccccaatca tttgaccata ttcatttact
     1321 ggcatagctt tctccttttt tcacttttca aactttatag ttgcccatag tataccatac
     1381 tttcataaga agattcaaaa aatcctccag attctactct gaaggattcc taccttattt
     1441 cacaacgata ttaacgagtt tagttggctc aaacagtttg ggaaactgtt tgaggttgga
     1501 aatcagcaaa taaattggtt attttacaac aatattaacc aatttatttg gtacactaat
     1561 cactttcacg atttccttac cgtcaatttc tgctttgact ttttcatccg ctagagcaat
     1621 ttcttgcaat tcttcacgtg ataggtcttt agcgaccatg agtttggcac ggactttacc
     1681 tttgatttgg acaacgattt cgatttcgtc ttcaaccagt ttactttcgt cccaagttgg
     1741 ccaagctaca taagagattg actcacctgt ttctgcgact gtttgccaga gttcttctgc
     1801 caagtgaggt gcaaatggtg caatcaattg aataaagcct ttggcatagt caacataaag
     1861 cttatcttcc ttgttagtag cattgacaaa gaccataagt tgggcaatag ctgtgttgaa
     1921 tttgagagac tcaatttgct cagtaacagc tttgactgtt tcgttgtaaa ccttgtcaag
     1981 agcaccattg ttttccgcaa ggatttcttt acttgtaatc aaacggtaaa ctcggtcaag
     2041 gaacttacgg cttccttcca aaccttcttc tgaccaagca atcgaagcat cgagtggtcc
     2101 cataaacatt tcataaacac gaagggtatc ggcaccgtat tgttccacca catcgtctgg
     2161 gttaacaacg ttcttgagcg atttagacat cttggctggc gcttgctcca actcttcccc
     2221 tgtttctaca tggaagaagg aaccatcacg tttttcaacc ttgtcggttg ccacaagagc
     2281 accacggtgg tcacggtagc ttgttcccaa aatcatccct tggttaaaga gtttttggaa
     2341 tggttcctta gtcggaacaa caccgaggtc atagaggaat ttatgccaga aacgagcata
     2401 aagcaagtga agtacagcat gttccgcacc acccacgtag atatctactg gcaaccattg
     2461 tttgaggagg tcctcatcag ccaatttctc agtattgtgc gggtcaatat agcggaggta
     2521 gtaccagctt gaaccagccc attgtggcat agtgttggtt tcacgacgac ctttgacacc
     2581 atcttcacga gtcacttcaa gccaatctgt caagttagct agtggacttt caccagtacc
     2641 tgaaggacgg atatccttgg ttacaggcaa gacaagcggc aattcagttt caggaacagc
     2701 tgttgaagtt ccatcttccc aatgaatgat tggaattggc tcaccccagt aacgttgacg
     2761 gctaaagagc cagtcgcgga gacggtaggt aaccttctcc tgaccacagc ctttttcttc
     2821 caaccaagcc acaatcttgg caatagcgtc ttctttgttg agtccatcta ggaagtctga
     2881 attgacatgc aggccatcct ctgtgtaggc agcttcttcg acatttccac cttcaagtac
     2941 ttcgacgatt ggaaggtcaa attgtttggc aaattcccag tcacgttggt cgtgggcagg
     3001 cacagccata accgcacctg ttccataact agcaaggaca tagtctgcaa tccagattgg
     3061 catttcctta ccattgacag ggttgatggc ataagcacca gtccaaaccc ctgttttttc
     3121 tttagcaagg tctgtacgag ccaagtcaga cttaaggctg gcttggtgtt tatagtctgc
     3181 tacagcttct gcttgctctg aacttgtgat agcgtctact aattcatgtt caggagccaa
     3241 gacagtgaaa gtcgcaccga aaagtgtgtc cggacgagta gtaaagactg taaattcctt
     3301 gtctgttcct tttactttga aagttacatt ggcaccagtt gatttaccaa tccagttgcg
     3361 ttgcatatcc ttgatagact ctgaccaatc tagttcatct aagtcattga gcaagcgctc
     3421 tgcgtaagcc gtgattttga gcatccattg gcgcattggt ttgcggacaa ctggatagcc
     3481 tccacgctca gaagttccgt caggaagcac ttcttcattg gcaatggcag ttcccaattc
     3541 ctcaacccag tttactggca cttcagcttc ataggccaag cctttttcgt aaagcttggt
     3601 gaaaatccat tgagtccact tgtagtagtt tggatctgtt gtgttgactt cacgatccca
     3661 gtcataagaa aatccaagcg cattaatttg acgtttgaag ttggcaatgt tttccgctgt
     3721 aaattctgct gggtcattac cagtatccat agcgtattgc tctgcaggca aaccaaaagc
     3781 atcccaaccc attgggtgaa ggacattgta gccttgcgca cgtttgtaac gactgaggat
     3841 atcggttgca gtataacctt ctgggtgtcc tacgtgcaga ccagctccag acggataagg
     3901 gaacatatca agcgcataaa acttaggttt tgatgcatct gttcctgtct taaatgtatg
     3961 atgttctgcc cagtagccct gccacttagg ctcaatttct ttatgattgt aaaaactcat
     4021 ggtctctctc caattttgtg atgttactat tataccattt ttgagggaat ttgaaatgtg
     4081 tttaaaggaa aaactgtata ctgtatctca ttaattttga tgactatgaa ttgctctatc
     4141 tcccactttt tatcccattg ttatgcagta aatcaaggag taagtcaaga agcttatctc
     4201 gtatagcaca aaatacttat tttagaccga agataaaact ggaatgctaa ttaatgtatt
     4261 cacaataaat agccgacaac ctatgtcgct ttttgattta tgaagaacgt atagtggact
     4321 gaatctgaaa tagtacgaaa caattgctaa aacattgtta gaaattaatt ttactttccc
     4381 aatcgatttg ttctcatctt atttcaatct gctatagaat tcaatacgag gatcaataaa
     4441 agactaccat ttggaaaaca gtagtcctta ttgtttattt tgaatttaca taggaatcta
     4501 cagcgataat agcttgagca acatctgaag gcgaaatctt aaacggcatc tgatgaattg
     4561 tctcaccctc catagttgct tgtttaccaa cttttattaa atcatcatat ccaacttgat
     4621 ccaaatgcat ttcttttaga gttgttggca taccaatttt tttgtaaaac tcaatatact
     4681 tatcaagttc ttctttaggt ctattttcca ataatagttg tactaaagtt ccataagcta
     4741 ctttttcacc atgtgttaaa tgatgaatgt cacctgtcaa tgcagtaaaa ccattatgaa
     4801 ttgcatgcgc cgcagctaat cctccacttt caaaacctag accactcaat aaagtattag
     4861 cttcaacaat attttctaat gctggtgtca ccactttagc ttcacaagct gccatagcct
     4921 gtaaaccatc tgcaaacagc gtttcttcac atttcttcgc aattgcaact ccagccaatg
     4981 tttgctgttg tcccaacata gtttttccat ttgcctgcat aaccgcacgc gcctcaaccc
     5041 aagttgctaa accatctgca ataccagacg ctaataaacg cttaggggct tgtgaaataa
     5101 cttttgtatc aaccaaaact aaatctggat ttttagaata aaatagataa tgatcaaatg
     5161 caccttcatc tgtataaata acagataaag cagatacagg tgcgtcggtc gatgcaattg
     5221 ttggagcaat aataacaggc ttttcaatca aatctgcaat agcttttgcg ctatcaatcg
     5281 tctttccccc accaagaccg ataatactat cacaattttc tttctcagcc aaggcaacaa
     5341 ctcgattgat ttcattgtca gaagcttcac cattaaatag cgccagaaca atatggaaac
     5401 catacctatg taggtaatct tcaaatcgtt ttccaacaat atcataaacc aactgatcgc
     5461 ataatagaat agggcaattt cccaaatcca aaattgattt ggcattttca aacaaggcat
     5521 tttccccctg aatatatcta gaaggactag caaaaattct catatgtatt tcctctctat
     5581 ctaaatggaa cgactatttt gaataacaaa ccaatcgtca gaaaaatcat caaccgcctt
     5641 ttggatagat ggcatggcga aagctgattc aaaaacatcc gctcctgctg taacagcatg
     5701 cgcacctgca gctaaagcat tatttacttg tgctacattt ttaaaggatg cagctaaaat
     5761 cttactagga gagttctgtc tatcaatagc aagagctaat tgacgaatga cagaatttga
     5821 atcaatgttc agattttcca ttctattata atatggagct aggtaatccg ctcctgcttc
     5881 gatagctaat aatccctgaa taactgtata aatagctgtt gcagtgatat ggtagccctc
     5941 tttttttagc gcctttattg cacgtaatcc agctggagta acaggtactt tgataaatat
     6001 atcatctcct gcttgtcttc gaattttatg agcatccttt aagatgcctt caaaatcttg
     6061 agaaatcacc tgaacatgaa tagagggtgt agagccaatc aattctctta catctttgat
     6121 tcgttcaaaa aaattaatag aaccctctct ttttgcaata gtgggatttg aagttacccc
     6181 agctagcggc aaaatttcag accacttttt aatctcatct aaatttaatg tgtcaagcat
     6241 aaattccata aaaagaacct ctttatttta caaagtatgc tcagtacgtc ctataatgtc
     6301 atcttgggtt gccttagaaa gaacattgaa gaatgcagag tatcctgcaa cacgaacaat
     6361 taagtctctg tgtttttcag gatgtttctg agcgtcaatc agcgtctctc tggaaacaac
     6421 attgtattga atatggtacc catgtaaacg attaaagaat gttcgtaaca aagcaattag
     6481 ttttaattta tcttcttctt tggctaacgt ttgaggattt actttctgat ttaagagaac
     6541 cccacctacg atttcatctg ttggtaattt tgaaacagat tttaaaacag atgtagggcc
     6601 gtgttgatcc atattatgtg atggtgaaca accctctgct aacggtgtac ccgcgttgcg
     6661 tccatctgga gttgctaatg ttccacgtcc ctgccctacg ttggctgaga tagaagatgt
     6721 tcctgaataa cgaattcctc caattggacc tcttccataa cgtgtattag gatatttagc
     6781 aatttcatca acataaatgt cataagcagc agtaaccaat ttgtcagcat aatcatcatc
     6841 attaccatac ttaggtgcat catgaatcaa catttcttga atgaccttac cttcttctcc
     6901 ggcataatct gtttccagtg catgccaaag ctgacttggg cttatacgtt cttcctcaaa
     6961 caccaatttt ttaattgcag ctaatgaatc cgacaaattt gcaattccaa cttgcaatcc
     7021 tgatatataa tcatatactg ctccaccttc tttaaggtgt tttccacgac caatacaatc
     7081 atcagtcaat gctgaacata gaatatcagg aacttctcgt tccaatgata aatcaataga
     7141 attttcaaca ataacactca ttcgtgtcaa atatcttagt gttttatccc aagcattttc
     7201 taattcagaa aagttcttca tatccttaaa atgaccaaag cttggtgcaa accgtttacc
     7261 cgaagccgga tcaattccat cattcatcgt gataagtaga accttaggga agttcatata
     7321 actcatacct gtgcaacgat agccccattt ccctggaact gccgtttcaa cacatccaat
     7381 ggcactgtaa tcataagcat catcttccaa tactcctttt gcaataaaag aaggaataat
     7441 aatctcatca ttattaaatg caggcatacc aaaaccaagt ttcatcactt caatacactc
     7501 attcatgaaa cgagcatcta aacctgcatg gtaacgtaca gttagattag gttgcggtag
     7561 atgggtttgt gcaactgatt ttaataccaa ataagataat gggttaacag catccttctt
     7621 atctcgagtc tgtccaccaa ttgtaacatt ttgatataaa ggacttcctg ctgaagaaaa
     7681 tgtatgtgat tgactgcgaa ccttattaat tgtaattgtc ttaatccaaa gatttgtcag
     7741 acgttcaaca atgctatctt ctgtttcttt accactttct aaatcagcct tcatatatgg
     7801 atacatatat tgatcaaaac ggccatatga aagagagtgg ccattagatt caatttgtaa
     7861 aatacattga ataaaccaaa ctgattgaat agcttctgca aaagtagttg ccggttcata
     7921 tgggactcta gagcaaatat ctgcaatctc aagtaattct ttcttacgtt taggatttgc
     7981 attttcggct aaacttttag caagagcaac aaagcgcttt gcatatactt taatagcatc
     8041 gattacgata aatatagagt cgtaaaaatg atatttatca atacttgctg gatctgttaa
     8101 atctagagct acttttgctt tatgagcccg ctcttcaaaa cctcttaaac caaattgcaa
     8161 aagtttctga tagttaactg ctaagtgagc atctccagaa ttcatcttac cttccatacc
     8221 gaagaatcct gtttccatat aaacagacac ttcttcaggt aataaggcac cagctctagc
     8281 acgtaaatta ttattttccc aaaacggagc aatacttcta agttgttctt ttgtttcttc
     8341 tgtaatatag aaaacatctc catcacgctt ttcaaaaaga tccaactcat tgagaacaaa
     8401 ttctagcgta tattccggaa aaataggagc atctttattg gaagaagctt gatttcccgc
     8461 aatcatagat tcttcttcaa tatagataga catattttcc aaaatttctt tcagcatata
     8521 tgcacgtttt aggacattag gttgttcctt gtatcgttca taggcgcgtg ttgctagaac
     8581 tgctctctca gcatcaatat aaggtttttt atttaaaaca tcttctcgat atttgttcat
     8641 cctttcagta aggctgccaa aatattctgt cttgattgtt gttcttgcta cttctgtatt
     8701 taccatcgca accacctttc tttcgaaaat atttttattt ctttcgaaaa tataataccg
     8761 atttttatag aaattttcaa gcttttaact agaaaaattt taactctcta atttttagca
     8821 caaatgtgtg agtttaacag taacacacaa atacctctaa gattgtttga tttcattttg
     8881 gtaagctaaa cgatcttgta tcttaaagaa tggaaagtaa accactgtag atatcatcaa
     8941 tactaataac tgagtcacaa caccttgcca tccacccacc aaaaatcctg atagaatagc
     9001 tggtgtactc caaggcaatg ttacccctga gaatggctgc atgaaacctg ttgcaatagc
     9061 tccatatact atcacagctg caagtacagg aacaagaatg aaaggtacaa acataactgg
     9121 attcatgaca atcggaaatc caaatacaac tggctcattt acgttaaata ttgctggaaa
     9181 agctgcaact tttcctaagg cttggtattg ttttgatttt gctgcaaaaa gcatggcaac
     9241 tacaagacca aacgtaatcc ctgaacctga tagaattaaa aatgaatcta aaaattgttg
     9301 agtaacaata tgtgcaccat tttctaatga tagattacca gaggctaaca tagctttatt
     9361 agcatcaaga ttagataaaa gcagagctgt cactactcca tttactaccg attgcccatg
     9421 aacaccaaac caccacaaaa atgatataaa gaatgcaatt ccaattgcac cataccaaga
     9481 tccagttaaa ccttgcaatg gaacttgaat agcagaataa atcatttcta tgaatgttcc
     9541 gccattagtc aatgacttcg ctaaaatata tacaatcata gaaagtaaga aaattacaaa
     9601 tgctggaatc attgcttcaa actgtttggc aatagcttgt ggaacttgtt ctggcatctt
     9661 aataacaatt tttctcttta taaagaaggt ataaatactt cctactacca aacctataat
     9721 gatagcaccg ataattcctt ggcctccaaa ccaaacttta ctaatagcgt ccccaatcgc
     9781 ctcaccttgt ttagggatat aagatgatct tagcaaaata aagaatgcag atacagatag
     9841 aactccagct ggtaaagcct ctactccgct attcttagca taagaatagg caattgaaaa
     9901 acaagaaatt agacccataa tagcaaaagt tcctgaatat acttgcataa acggctctgt
     9961 ccaattagct ccaaaaacac tagcaatgct cttatttaat ccttcgaacg gcaattgtcc
    10021 cataatcaag aataaactac caactactgt caatggcaaa attgctaaca tcccatcttt
    10081 tagagctata atgccacgca tattcacaaa cttcatcatc ggtgcaatga ttttctgaac
    10141 atccatcttt gccataataa atctcctttt cttacccact aatcaaagat agggccaaat
    10201 ctaatacttt tttcccatct aacataccat agtccatcat cggaataaca gctatcggaa
    10261 catcacactt atcacaaatt tcttttgatt tatctaatgt ataagcaact tgtggaccca
    10321 atagtgcaac atctatattt ggcgcataat ccgctaattt agactgagaa aacgcctcta
    10381 tttctgcctc aactccacta gcttgcgctg caattttcat attatttaca agcataccag
    10441 tagaaaaacc tgctgcacaa aacaaaccaa tcttcaccat tatgttttcc tcctctatgt
    10501 taataacaat gataatactc tagtattatt ttttatgaag ttcttttctc aaactaataa
    10561 tttctttgat taaattaatc tccgtcatac tagtcatgag atgatcttgt gaatgaacaa
    10621 agagagctgt aatttctgtc tttgtaccag acgcttcttg tgccaagaat tttgtttgta
    10681 gattatgggc ttctaataag gcggcatcag ctaactggat ttcttcttca caccgttcac
    10741 atgtaccatt ttttatgtaa tctaacgctt tataaatatg ttgtttcgca tcaccagcat
    10801 ataaaattaa acccatgata atttgatctg gaacaataat ttccataaat tcctcctcat
    10861 ttcactatgt aaaaagcttt tttcatttg
//
LOCUS       DAVLTT010000061        10864 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLTT010000061 DAVLTT010000000
VERSION     DAVLTT010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10864
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.061"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            176..673
                     /locus_tag="VYN15_001740"
     CDS             176..673
                     /locus_tag="VYN15_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV1453029.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            673..2328
                     /gene="dnaX"
                     /locus_tag="VYN15_001741"
     CDS             673..2328
                     /gene="dnaX"
                     /locus_tag="VYN15_001741"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV1453030.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLPALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKSEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLAGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2356..2550
                     /locus_tag="VYN15_001742"
     CDS             2356..2550
                     /locus_tag="VYN15_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV1453031.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2700..3470
                     /gene="sufC"
                     /locus_tag="VYN15_001743"
     CDS             2700..3470
                     /gene="sufC"
                     /locus_tag="VYN15_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV1453032.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEISAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3498..4760
                     /gene="sufD"
                     /locus_tag="VYN15_001744"
     CDS             3498..4760
                     /gene="sufD"
                     /locus_tag="VYN15_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV1453033.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4771..5997
                     /locus_tag="VYN15_001745"
     CDS             4771..5997
                     /locus_tag="VYN15_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1453034.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVINPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5984..6415
                     /locus_tag="VYN15_001746"
     CDS             5984..6415
                     /locus_tag="VYN15_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000009523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV1453035.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQ"
     gene            6478..7890
                     /gene="sufB"
                     /locus_tag="VYN15_001747"
     CDS             6478..7890
                     /gene="sufB"
                     /locus_tag="VYN15_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV1453036.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8121..9362)
                     /locus_tag="VYN15_001748"
     CDS             complement(8121..9362)
                     /locus_tag="VYN15_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV1453037.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIIQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9465..10574
                     /locus_tag="VYN15_001749"
     CDS             9465..10574
                     /locus_tag="VYN15_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1453038.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
BASE COUNT         3220 a         1983 c         2350 g         3311 t
ORIGIN      
        1 ttgttttgtc gcttttcatt ataggtcata tgggactttt tttctacaat aaaataggct
       61 ccataatatc tataagggat ttacccacta caaatattat agagcccaaa atcctttgtt
      121 tactaaacaa gggatttttc ttttgtctct gctccttttt tgatataata gttctatgtt
      181 aaaatcagaa aaacaatcac gttatcaaat gttaaatgaa gaattgtcct tcctattgga
      241 aggcgaaacc aatgttttgg ctaatctttc caacgccagt gctctcataa aatcacgttt
      301 tcctaatacc gtatttgcag gcttttattt gttcgatgga aaggaattgg ttttaggccc
      361 cttccaagga ggtgtttcct gcatccgtat tgcactaggc aagggtgttt gtggtgaggc
      421 agctcacttt caggaaactg ttattgttgg agatgtgacg acctatctca actatatttc
      481 ttgtgatagt ctagctaaaa gtgaaattgt ggtgccgatg atgaagaatg gtcagttact
      541 tggagttctg gatctggatt cttcagagat tgaggattac gatgctatgg atcgagatta
      601 tttggaacaa tttgtcgcta ttttgcttga aaagacaaca tgggacttta cgatgtttga
      661 ggaaaaatct taatgtatca agcactttat cgaaaatata gaagtcaaaa cttctcccag
      721 ttagttggtc aagaagttgt ggctaagact cttaaacaag cggtggagca agagaaaata
      781 agtcacgctt atcttttttc tggtcctcgt ggaacgggaa aaaccagtgt tgctaaaatc
      841 tttgccaagg ctatgaactg tcccaatcaa gtgggtggcg aaccttgcaa taactgctat
      901 atttgtcaag cagtgacgga cggtagttta gaagatgtca ttgaaatgga tgcagcttct
      961 aataatgggg tagatgaaat tcgcgaaatt cgtgataaat ctacctatgc gcctagcctt
     1021 gctcgttata aggtttatat catagatgag gttcacatgc tgtctacagg ggcttttaat
     1081 gccctcttaa agacgctgga agaaccaaca cagaatgtag tctttatttt ggccactact
     1141 gaattgcaca agattcctgc tactattcta tcccgtgtgc aacgttttga gtttaaatca
     1201 attaagacac aggatattaa ggaacatatt cactatatct tagaaaaaga aaatatcagt
     1261 tctgaaccag aggctgtgga aatcattgcc agacgggcgg aaggtggaat gcgggacgcc
     1321 ttgtctattt tggatcaagc cctgagtttg acacagggaa atgagctgac gactgctatc
     1381 tctgaagaaa ttactggcac cattagccta ccagccttgg atgattatgt ggcggccttg
     1441 tctcaacagg atgttcccaa agctttgtct tgcttgaatc ttctttttga caatggtaag
     1501 agcatgactc gttttgtgac cgatcttttg cactatttaa gagacttgtt aattgttcaa
     1561 acagggggag aaaatactca tcatagttca gtctttgtag aaaatttggc acttcctcaa
     1621 aaaaatctgt ttgaaatgat tcgcttagca acagtgagtt tagcagatat taagtctagt
     1681 ttgcagccca agatttatgc tgaaatgatg accgtccgtt tggcggaaat caagtccgaa
     1741 ccagctctat caggagcggt tgaaaatgaa attgctacgc tgagacagga agttgcccgt
     1801 ctcaaacaag agctttctaa tgtaggtgcg gttcctaaac aagttgcacc agctcctagt
     1861 cgaccagcta cgggcaaaac agtctatcgt gtcgatcgca ataaagtgca atctatctta
     1921 caagaggccg tcgaaaatcc tgatttagca cgtcaaaatt taattcgttt gcagaatgcc
     1981 tggggagagg taattgaaag tctaggtggg ccggacaagg ctctgctagc tggttctcaa
     2041 ccggttgctg ccaatgaaca ccatgctatt cttgcttttg agtctaactt caatgctggt
     2101 caaactatga aacgagacaa tctcaatacc atgtttggta atatcctcag tcaggcggca
     2161 ggtttttcac ctgagatttt agctatttcc atggaggaat ggaaagaagt tcgcgcagcc
     2221 ttttcagcca aagccaaatc ttctcaaact gaaaaagaag tagaagaaag cctgattcca
     2281 gaaggatttg aatttttggc tgataaagtg aaggtagagg aagactaaag aaagatttca
     2341 tgatacaata agtttatgaa taaacaacaa tttattatta tggcgctatt tacagctgct
     2401 gagacctatt ttttcaatga agcctggatg actggccgct atattatggc agccttttgg
     2461 gcaattttac tctttagaaa tttccgagtc agttatgtga tgggtaaaat cgttgatgtc
     2521 atcgatcagc attttaatag gaaagactag ccctcagctt ccagacaaaa tcaaagcctt
     2581 ttaggctttt ttttgttata ctagaaaagt atatttatag aatttttgct ctatttctgg
     2641 ggaaatcaga cgtttttcta gtaagtactg taaaagtttt gaaaaagaaa ggaactatca
     2701 tgtcagtatt agagatcaaa gatcttcacg ttgagattga aggaaaagaa attttaaaag
     2761 gggttaacct gaccctgaaa acaggagaaa tttccgctat catgggacca aatggtacag
     2821 gtaaatcgac tctttctgcc gctatcatgg gaaatccaaa ctatgaagta actaaaggtg
     2881 aagttttgtt tgatggcgta aacatccttg agttggaagt ggatgagcgt gcgcgtatgg
     2941 gacttttcct tgctatgcaa tacccatcag aaatccctgg aattaccaat gctgagtttc
     3001 ttcgtgccgc tatgaatgcg ggtaaagaag atgatgagaa gatttcagtt cgtgagttta
     3061 ttactaagct agatgaaaaa atggaattgc tcaacatgaa agaagaaatg gcagagcgtt
     3121 acctcaacga aggcttctct ggtggtgaga aaaaacgcaa tgaaattctt caacttttga
     3181 tgttggagcc aacatttgct cttttggacg agattgactc aggtcttgat attgacgctc
     3241 ttaaagttgt gtctaaaggt gtcaatgcca tgcgtggtga aggttttggt gctatgatca
     3301 tcactcacta ccaacgtctt ttgaactata tcacacctga tgtggtacac gtgatgatgg
     3361 aaggtcgtgt tgtcctttct ggtggtccag aattggctgc gcgtttggaa cgtgaaggat
     3421 acgcaaaatt agctgaagaa cttggctacg actacaagga agaattgtaa ttccctcgta
     3481 tcttttagga gaagtaaatg actagagaaa atattaaact tttttcagaa atgcacgctg
     3541 aaccaagctg gttggctgat ctccgtcaaa aagcttttga caagattgag actttggaat
     3601 taccagttat tgagcgtgtc aaattccacc gttggaatct gggtgatgga acgattacag
     3661 aaaatgagcc atcagcaaat gttccagatt tcacagcttt agatcatcac ttgaagttgg
     3721 tgcaagtagg aactcaaact gttttcgaac aaactccagt tgagttagct gaacagggtg
     3781 ttgtcttcac agactttcac tcagctttag aagaaattcc agagctgatc gaagaattct
     3841 tcatgtcatc tgttaagtat gatgatgaca agttggcggc ttaccacaca gcttacttta
     3901 acagtggtgc tgtactctat attccagata acgtagaaat cacagagcca attgaaggaa
     3961 ttttctacca agatagcgat agcaatgtgc cgtttaacaa gcatattatg attatcgctg
     4021 gtaaaaattc taagattagt tatctggagc gtttagagtc acgcggtgaa ggaagtgaca
     4081 aagtaactgc caatatcaca gtggaagtga ttgcacgttc tggtgcgcaa gtcaagtttg
     4141 ctgctatcga ccgtctaggt gaaaacgtca ctgcctacat tagccgtcgt ggtaaattag
     4201 gcaacgatgc aagtattgac tgggctatcg gtgtcatgaa cgaaggaaat gtcgttgctg
     4261 attttgatag tgacttgatt ggtaatggta gccatgctga cctcaaggtt gtagctcttt
     4321 caagtggtcg tcaggtacaa gggattgata ctcgtgtaac taactatggc tgcaactcta
     4381 tcggaaatat cctacaacat ggggttatcc ttgaaaaagc aactttgact ttcaatggta
     4441 tcggccacat catcaagggt gctaagggag cagatgcgca acaagagagc cgtgttctca
     4501 tgctttcaga ccaagcgcgt tcagatgcta acccaattct tttgattgat gaaaatgatg
     4561 tcactgcagg acacgcagcg tctatcggac aagttgatcc agaagacatg tattacctca
     4621 tgagtcgtgg attggataag gcaactgcag agcgtttggt tgttcgtggt ttccttggat
     4681 ctgttatcgt ggagattcca gtcaaggaag ttcgtgatga aatgattgca actatcgaag
     4741 agaaattgtc aaaacgctaa ggggaagcct atgttagatg tagaagcgat tcgcaaggat
     4801 tttccaattt tagatcagat tgtcaatgat gaacctctgg tctatctgga caatgctgcg
     4861 acgacacaaa aaccactagt agttctgaaa gctattaaca gttactatga gcaggacaat
     4921 gccaatgttc accgtggtgt ccatacctta gcggaacgag cgacagcttc ttatgaagct
     4981 gctcgtgaaa ccattcgtaa gtttattaat gcaggctcta caaaggaagt tctctttacc
     5041 agaggaacga caaccagcct taactgggtg gcacgctttg ctgaggaaat tctcgctgag
     5101 ggagaccagg tcttgatttc agtaatggaa caccattcta atatcattcc atggcaggaa
     5161 gcttgtcgaa agactggagc agagcttgtc tatgtctatc ttaaagacgg tgccttggat
     5221 atggaggatt tgcgagctaa attgactgat aaggttaaat ttgtttccct agctcatgcc
     5281 tccaatgttc ttggtgtgat caatccgatc aaggaaatca ctcaattagc ccaccaagtt
     5341 ggggcaatca tggtagtgga tggtgctcaa tctacacctc atatgaagat tgatgtccag
     5401 gacttggatc tggacttttt cgccttttcg ggtcacaaga tggctggtcc gactggtatc
     5461 ggtgtccttt acggcaaaga aaagtatctt gagcaaatgt ctccagtaga atttggcggc
     5521 gagatgattg attttgtcta cgagcaattt gctagttgga aggaattgcc ttggaaattt
     5581 gaggctggaa cgccaaatat ggcaggagct attggacttg cgactgcagt tgattatctg
     5641 gaaaagattg gtatggatgc cgttgaagct catgaacagg aattgattgc gtacgtctat
     5701 ccaaaactgc aggcaattga gggattgacc atttacggtt ctcaggattt ggctcaacgt
     5761 tcgggtgtta ttgcctttaa cctaggtgat ctccatcctc acgatcttgc gacggctctg
     5821 gattatgaag gagtggctgt tcgtgctggt catcattgtg cgcaaccctt gcttcagtat
     5881 ttggaagtcc cagcaacagc tcgtgcaagt ttttatatct acaataccaa ggcagattgc
     5941 gacaaactag tcgatgccct acaaaagaca aaggagtttt tcaatggcac tttctaaact
     6001 agatagcctt tatatggcag tggtagcaga ccattcgaaa aatccacatc accaagggaa
     6061 gttagaagac gctgagcaaa tcagtctcaa caatccgact tgtggggatg tcatcaacct
     6121 ctctgtcaag tttgatgcag aggaccgttt ggaagatatt gcttttctaa attcaggatg
     6181 cacgatttca actgcttctg ctagtatgat gacagatgcc gttttaggaa aaaccaaaca
     6241 agaaatttta gaactggcga ctattttttc tgaaatggtt caagggcaaa aagatgagcg
     6301 tcaagaccaa cttggagacg cggcattctt gtcaggtgtt gccaaattcc ctcaaagaat
     6361 caagtgtgca accctagctt ggaatgccct taagaaaaca attgaaaatc aataaaaaca
     6421 gtaagacaag tttcttttgt cttatgaatt attagaaatg aagaaagaaa ggatattatg
     6481 gctgaagaaa gagtagaacc aaaaccaatt gaccttggtg aatataaatt tggtttccat
     6541 gacgatgtag agcctgtctt atcgacagga aaaggactca acgaaggtgt tattcgtgaa
     6601 ttatctgctg ctaagggtga gcctgagtgg atgttggagt tccgtttgaa gtcttatgaa
     6661 accttcaaaa aaatgcccat gcaaacttgg ggagcagact tgtcagagat tgactttgat
     6721 gacttaatct actaccaaaa accatctgac aaaccagccc gttcttggga tgatgtacct
     6781 gaaaagatta aagaaacctt tgaacgtatc gggattccag aagctgaacg tgcttattta
     6841 gcaggggctt ctgcccagta cgagtcagaa gtggtttacc acaacatgaa ggaagagttc
     6901 caaaaattag gtattatctt tacagataca gattccgcac tcaaggaata cccagactta
     6961 tttaaacaat actttgcgaa gttggtaccg ccgacagata acaagttggc agccctcaac
     7021 tcagcagtat ggtcgggtgg aacttttatc tacgtgccaa aaggtgtcaa ggtagatatt
     7081 ccacttcaaa cttatttccg tatcaataac gaaaatatag gtcagttcga acgtaccttg
     7141 attatcgttg atgagggagc aagcgtccac tacgtagaag gatgtacagc accaacatat
     7201 tcaagcaata gcttgcacgc tgccattgta gaaatttttg ctttggacgg agcttatatg
     7261 cgttatacaa ctatccaaaa ctggtctgat aacgtctata acttggtaac aaagcgtgct
     7321 aaggctcaaa aggatgccac tgttgagtgg attgatggaa acttgggtgc caaaacgact
     7381 atgaaatatc catctgttta ccttgatgga gaaggagcgc gtggtaccat gctctctatc
     7441 gcctttgcta atgcagggca acaccaagac acgggtgcta agatgattca caatgctcca
     7501 cataccagct cgtctattgt gtctaaatcc atcgctaaag gtggaggaaa ggttgactac
     7561 cgtggacaag tcacctttaa caagaactct aagaaatctg tttcccacat tgaatgtgat
     7621 accattatca tggatgactt gtcagcatca gatactattc catttaatga aattcacaac
     7681 tcgcaagtgg ctttggaaca cgaagccaaa gtatctaaga tttcagaaga gcaattgtat
     7741 tatctcatga gccgtggatt gtcagaatct gaggcaactg aaatgattgt catgggattt
     7801 gtagaaccct ttacaaaaga acttccaatg gaatacgcag ttgagctgaa ccgcttgatt
     7861 agctatgaaa tggagggatc agttggataa aatttgattt tatactcttc gaaaatctct
     7921 tcaaaccacg tcagcatcgc cttaccgtat gtatggttac tgacttcgtc agtttcatct
     7981 acaacctcaa aacagtgttt tgagcaacct gcggctagct tcctagtttg ttctttgatt
     8041 ttgagtatta gatttactca aaatcaagga ttttgaagat gaacttgtat caaaaaatcg
     8101 cggtttaaaa tcgcgatttt ttataatttc tcgttaacaa agcggacaaa ctgattccac
     8161 caaactttta agaagaaggc tttttcaatt ttcttgtctg ctaccatttc gaaactaggg
     8221 cgctctgtgg tgatgtaacc ttgaccaatc aagtccttgt cttcataagt caaatggcca
     8281 accactgttc cagcttcaag tggtgctggg attgctttgg aatcaggtgt gaattgaaca
     8341 gattgggaag attgattccc aacacgttcg attagataga tatcctctgg agccactgca
     8401 gttactgtat cttcttttcc atcttgtaca ggggctttgc tatcttgata ggcatcgcct
     8461 tgttgaatga ttttgcgaag tgtaaatgta gaagaaatat aatccattag ggaagatgta
     8521 gctgtaaatc gagcgtaagg attattgtct tgatgatctg catttaaaac aactgtgatg
     8581 actctcatgc ctttttcgac agtagtacca acaaaagact ctccagcctt atctgttgtt
     8641 cctgttttta gcccatcaaa accaccacgg taagcaggca taccttctaa catgtagttg
     8701 gttgaagtga ttgtcatccc agcaaaagta gaagaaggtt ttttggtgat ttctaagact
     8761 tgtgggtatt ttttgatgag gttgcgagca acgatagcga catcataagc actaagctta
     8821 ttttcctcat cttttttaga acctgggtaa atgttatccc ctagagtttc attgttaaga
     8881 cctgtcgtat tgacaacagt ggcatcctga attccccatt ccaagagttt tgcccgcatc
     8941 atatcgacga aatctttttc tgagccagca attttctcag ctagggcaat agcggcgctg
     9001 ttggcactag ataccagagt tgcttcaagc aactcttcga cagtataatt acgggcctcc
     9061 ataggaatat tactggcttc agaatttgtc gtcaattgat aaggataatc agaaatatct
     9121 acaggagtgg agagggtaat acttccgttt tccaaagctt catagaccag ataaacagta
     9181 atcaattttg ttatggaagc aatttcgaca ggttgcgttg catccttctc atagagaatt
     9241 ttaccagtat ttgcctcaac agcaatcgca tgtttagcgg caatggtaaa atcttgagca
     9301 acagcagtag aagcaccccc taaaagagag acagttaaca aagttaaaaa tatttttttc
     9361 atagtagtct tattctatca taaagaaaaa aaatattctt gctttaataa ttcatctgtt
     9421 aagctttttg aaaatatggt aaaataaagt gagggaggta actcatgttt cgtagaaata
     9481 aattattttt ttggaccaca gaaattttac tcttaaccat catcttttac ctatggagac
     9541 agatggggtc tttgattaac ccttttgtta gcgtgcttaa tacaattatg attccatttt
     9601 tattaggggg ctttctttat tatttgacaa accctattgt tactttctta aataaagtct
     9661 gtaaactcaa tcgtttgctt ggtattttaa ttaccttgtg tactttggtc tggggaatgg
     9721 tcataggtgt tgtctatctc ttacctattt tgattaatca gttatctagt ttgattatat
     9781 ctagtcaaac tatttatagt cgagtacaag acttaatcat agacttatct aattatcctg
     9841 cgctccagaa tttggatgta gaagctacaa ttcagcagtt aaacttatcc tatgttgata
     9901 ttcttcaaaa tatcctaaat agcgtatcaa atagtgtggg gagcgtcttg tcagctctta
     9961 tcagtactgt tttgattttg attatgactc cagttttttt ggtttatttc ttattagatg
    10021 gacataaatt cttgcccatg cttgaaagaa cgattctaaa gagggatcgc ttgcatattg
    10081 caggcttatt aaagaattta aatgcgacga ttgctcgcta tattagtgga gtttcgattg
    10141 acgcaatcat tataggttgt ttggcttata ttggctatag tattattggt ttaaaatatg
    10201 ctttagtttt tgccattttt tctggtgtag ccaatttaat tccttatgtg gggccaagta
    10261 ttggtttgat tcctatgatc atcgcaaata tattcactga tccccataga ctgctgattg
    10321 cagtgattta tatgcttgtt gttcagcagg tagatggcaa tatcttatat cctcgaatcg
    10381 taggaagtgt tatgaaggtt catccaatca cgattttagt tttacttttg ttgtcaagca
    10441 atatctatgg tgtagttgga atgattgtcg cagtgccaac ctattctatc ttgaaagaaa
    10501 tttctaagtt cttatcccgt ttgtatgaaa atcataaaat aatgaaagaa cgagaaagag
    10561 aattagctaa gtaaaagtca ggagaaccct gatttttctt tactggaagt ggcctttaga
    10621 ttagaagact gaaaataagt taaagtctta aactaatttt cacagctaag aatagtagaa
    10681 gttaatctga taaaaatcga aaaaaccagt ggaattccgt gtcagggtaa gttccactgg
    10741 ttttcatagt ctattaaagt tcgaatgaaa cctatttata gtatattgaa actagaatag
    10801 tacacctcta attctaaaac attgttagaa atcgatttga ctgtcctgat ctattcgtcc
    10861 tatt
//
LOCUS       DAVLTT010000062        10849 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLTT010000062 DAVLTT010000000
VERSION     DAVLTT010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10849
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.062"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            14..736
                     /locus_tag="VYN15_001750"
     CDS             14..736
                     /locus_tag="VYN15_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1453039.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            733..1581
                     /locus_tag="VYN15_001751"
     CDS             733..1581
                     /locus_tag="VYN15_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1453040.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            1613..2542
                     /gene="psaA"
                     /locus_tag="VYN15_001752"
     CDS             1613..2542
                     /gene="psaA"
                     /locus_tag="VYN15_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV1453041.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            2665..3156
                     /gene="tpx"
                     /locus_tag="VYN15_001753"
     CDS             2665..3156
                     /gene="tpx"
                     /locus_tag="VYN15_001753"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV1453042.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(3252..5960)
                     /locus_tag="VYN15_001754"
     CDS             complement(3252..5960)
                     /locus_tag="VYN15_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1453043.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQDQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSSTNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLITGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVVAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(5962..6663)
                     /locus_tag="VYN15_001755"
     CDS             complement(5962..6663)
                     /locus_tag="VYN15_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1453044.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            complement(6913..9324)
                     /locus_tag="VYN15_001756"
                     /pseudo
     CDS             complement(6913..9324)
                     /locus_tag="VYN15_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
     gene            complement(9377..10069)
                     /locus_tag="VYN15_001757"
     CDS             complement(9377..10069)
                     /locus_tag="VYN15_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV1453045.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFIGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            complement(10520..10844)
                     /locus_tag="VYN15_001758"
                     /pseudo
     CDS             complement(10520..10844)
                     /locus_tag="VYN15_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3171 a         2502 c         2032 g         3144 t
ORIGIN      
        1 ggaatacaag tttatgatac gtatcgaaaa cctcagtgtc tcctacaaag aaacgttggc
       61 acttaaggat atttcactag tgctccatgg accaacaatt accggcatca ttggtccaaa
      121 cggcgctggg aaatcaacac tattaaaagg tatgctggga attatcccac atcaaggtca
      181 ggcatttctc gatgacaagg aagttaaaaa atccttacac cgaattgcct atgtcgaaca
      241 aaaaatcaat atcgactaca actttcccat caaggtcaag gaatgcgtct cgttaggact
      301 atttccctct attcctctct ttcgaagttt aaaggctaaa cattggaaga aagtgcaaga
      361 ggcccttgaa atcgtcggcc tagctgacta cgctgaacgt caaattagtc aactgtctgg
      421 aggtcaattc cagcgggtct tgattgccag atgtttggtg caggaagccg actatatcct
      481 cttggatgaa ccctttgctg ggattgactc tgtcagtgag gaaatcatca tgaatacgct
      541 gagagatttg aaaaaagctg ggaagacggt tctcatcgtt caccacgacc tcagcaagat
      601 tccccactac ttcgatcaag tcttacttgt caatcgagaa gtgattgcct ttggtccaac
      661 aaaagaaact tttaccgaaa ccaatctaaa agaagcttac ggtaatcaac tctttttcaa
      721 tggaggtgac ctatgattgc agaatttatc gatggattgc aaaaattcca tttcctacaa
      781 aatgccttga taacagctat tgtcgtcggg attgtagctg gagccgtggg atgtttcatt
      841 attctacgcg ggatgtcact catgggagat gccatttcac atgctgtctt accaggtgta
      901 gccctctcct tcatcttggg ccttgacttc tttatcggag ccattgtctt tggattgcta
      961 gctgccatca tcattaccta catcaaagga aactcgatta tcaaaagcga taccgccatc
     1021 ggcattacct tttcttcttt cttagccctc ggtatcatct tgattggtgt cgctaaaagt
     1081 tcaactgacc ttttccatat cctttttggt aatatcctgg ccgtccaaga tacggatatg
     1141 tttattacta tgggtgtggg ggcagccatc ctcttgttaa tctggatttt cttcaagcaa
     1201 ctcttgataa cttcctttga tgaactcttg gctaaagcca tgggaatgcc tgtcaatttc
     1261 tatcactacc ttctcatggt actcctgact ctcgtgtctg tgacagccat gcaaagtgtc
     1321 ggaactatcc tgattgtagc catgctgatt accccagctg caactgctta tctgtatgct
     1381 aatagtctga aaagtatgat tttcctttcc tcaaccttcg gagctactgc ttcagttttg
     1441 ggactcttta ttggctatag ttttaatgtt gcggcaggtt ctagtatcgt gcttacagct
     1501 gctagtttct ttctcattag cttctttatc gctcccaaac aacgatattt gaaactgaaa
     1561 aataaacatt tgttaaaata aggggcaaag ccctaataaa ttggaggatc taatgaaaaa
     1621 attaggtaca ttactcgttc tctttctttc tgcaatcatt cttgtagcat gtgctagcgg
     1681 aaaaaaagat acaacttctg gtcaaaaact aaaagttgtt gctacaaact caatcatcgc
     1741 tgatattact aaaaatattg ctggtgacaa aattgacctt catagtatcg ttccgattgg
     1801 gcaagaccca cacgaatacg aaccacttcc tgaagacgtt aagaaaactt ctgaggctga
     1861 tttgattttc tataacggta tcaaccttga aacaggtggc aatgcttggt ttacaaaatt
     1921 ggtagaaaat gccaagaaaa ctgaaaacaa agactacttc gcagtcagcg acggcgttga
     1981 tgttatctac cttgaaggtc aaaatgaaaa aggaaaagaa gacccacacg cttggcttaa
     2041 ccttgaaaac ggtattattt ttgctaaaaa tatcgccaaa caattgagcg ccaaagaccc
     2101 taacaataaa gaattctatg aaaaaaatct caaagaatat actgataagt tagacaaact
     2161 tgataaagaa agtaaggata aatttaataa gatccctgct gaaaagaaac tcattgtaac
     2221 cagcgaagga gcattcaaat acttctctaa agcctatggt gttccaagtg cctacatctg
     2281 ggaaatcaat actgaagaag aaggaactcc tgaacaaatc aagaccttgg ttgaaaaact
     2341 tcgccaaaca aaagttccat cactctttgt agaatcaagt gtggatgacc gtccaatgaa
     2401 aaccgtttct caagacacaa acatcccaat ctacgcacaa atctttactg actctatcgc
     2461 agaacaaggt aaagaaggcg acagctacta cagcatgatg aaatacaacc ttgacaagat
     2521 tgctgaagga ttggcaaaat aagcctctga aaaacgtcat tctcatatga gctggcgttt
     2581 tttctatgcc cacatttccg gtcaaatcat tggaaaattc tgactgtttc agatacaatg
     2641 gaagaaaaaa gattggagta tcctatggta acttttctcg gaaatcctgt gagctttaca
     2701 ggtaaacaac tacaagtcgg cgacaaggcg cttgattttt ctcttactac aacagatctt
     2761 tctaaaaaat ctctggctga ttttgatggc aagaaaaaag tcttgagtgt cgttccttct
     2821 atcgatacag gcatctgctc aactcaaaca cgtcgtttta atgaagaatt ggctggactg
     2881 gacaacacgg tcgtattgac tgtttcaatg gacctacctt ttgctcaaaa acgttggtgc
     2941 ggtgctgaag gccttgacaa tgccattatg ctttcagact actttgacca ttctttcggg
     3001 cacgattatg ccctcttgat caacgaatgg cacctattag cacgcgcagt ctttgtcctc
     3061 gatactgaca atacgattcg ctacgttgaa tacgtggata atatcaattc tgagccaaac
     3121 ttcgaagccg caattgcagc tgctaaagcc ctatagaaaa aatcctctgt cacaaagagt
     3181 tccctgctct ttgaaacgga ggatttttga atattagtaa atagaagttc aatcagctaa
     3241 aaataactac cttactctac agatttcagg gcttctaaca tatcaacctt tctcagataa
     3301 taattgacga agaaaccaag caaggtcaaa atgatgctta ctgctaccac tgggattaca
     3361 tagacttccc agcctacctg cggataaaag agaatagtcg caggcgaaat catttgaatc
     3421 aaaaattggt gtaaatagaa accagttatc agaccaagta cgattcccac aagggacagc
     3481 acaatcgtct cacggtaaat gtagagtgtg acttcattat tatgaaaacc aagaaccttg
     3541 atagtggaga gttcacggat tctctcagct acgttgatat tggtcagatt gtaaaggatg
     3601 acaatagcta atagaaccga tacgatgacc aagatggtca tggtctgatt gagtgagcta
     3661 gcgatagagt cgaagagtcg aatggctgaa gcattttgga caacgctaga caccgcagat
     3721 tgattcataa gcaagcccgc ctgactttcg atactagttg cactggtatc ccttaatgag
     3781 accagataag tgttggcttg gggtagctgt ccgtaaagtt gctcatagct agcctgactc
     3841 atataaataa agtgaccaac gtagttctca gtaatagcag cgacctttag ttccttacct
     3901 tcaatttcta aagtctgccc aaccttgaca cctgccagct gggcgagttt agctgtaata
     3961 acaatgccat cttttaatgt cagctcctgc tgatgatgtt gaagatggat aaagggagtc
     4021 aaatcttcct tctctatcat cataagagta atgttttgaa gaccagcctt gcctttgaaa
     4081 tccttgtcta gcgttttaga atagattttc tggtaggcta gtatctcctg ccctttcaac
     4141 acttctgcta gctctacctt gtcctgattg gtcgaactag gattttcaga gacaagcatc
     4201 tgatactgtt ggatttgttg aaactgttta gacggaactc ctgctacaga agattggatt
     4261 cccaaacctg caaagagcag agctacagaa cctgccacac caaagattgt catcaacatt
     4321 ctctgcttat aacgaaagat gttgcgggct gttaccttat gagtaaaact gagacgacgc
     4381 cagataaaac cgatacgctc caataagatt ttagctcctt tgacaggagg tttaggaagt
     4441 agaagctggg ctgcttcgtc atgaagttcc ctccaagcca ccagataggc tggtaacaca
     4501 ctcgccaacc agctcaagac aagagctagt aagctatagg tccaatagaa ctgaatctgg
     4561 gtttctccca ccaccatgcc ttttgtaatg acacttgaaa ttacactggc tagcaaataa
     4621 tgaccaagta tactacctag agccgttccg acagtcccag ctactagtcc ataaaggaga
     4681 aacttggcga taatatcctt actacggtaa cccaaggcct taaaaatccc tgcatgagtt
     4741 cgctcttcgt ctacaaagcg agtcatggtc gtaaaggtca ccatggctgc tacggcataa
     4801 agtaccacag gaaagatatt gcccactgct cgaatactgg atgaagcatt gctatacata
     4861 agatagccct gaccacctgg catggtctga cgattataga cctgatacct tggctccgcc
     4921 aaatcgtcca agacttgctg atgtttttct aatttttcct tttcttgggc tagattttgt
     4981 tcagcttgct ttagtttgtc ctcttccttg cccaattcct gcttggcttg ggtaagttga
     5041 gcactagcct gctctctctg aacttgagga aacaaggcta gttgactttc ttgagcctgt
     5101 atacgagctt gagcagctgc taaacgacgc ttgccttcct gcaaattagt ctgagccttg
     5161 tcaagggtct cttgcccctt gtctagagac tcttgtcctt cttttttcaa aagttgcaga
     5221 cgtaccttgc cattatctga taaagtttgt tcaaggtctt cctgatgttg cttggatttt
     5281 tcttcataag ctgatgaaaa ggcatttaaa cctgctaaat cttgatattt caaacgagct
     5341 atattgtaga ctttctgatc aaattgacta ggtaaaatca ccccataggc tgtcagagtc
     5401 ccacttccac ttcctgcgta gcccatatct cgctgggaga ggatttcagc cgaatccaca
     5461 aaaccagtaa tggtataagt atggtctttt aaagaggaat gaccctcttc tttttcttta
     5521 aaactaatct cctgtcccac gctgtattgg tcttgcaaat gagtggccaa agcgatttcc
     5581 ttgtctgact gaggaagtcg tccctttctt agctgaaagg ttgaaattcg ctctggtttg
     5641 gagtacagcc gaatggcatc ctgcccatta tccatagtca catctgtcaa atagccaaac
     5701 tcgacctctg cgccctccgt ctgttttagt tcttcttggt ctgcttgatc caagccatag
     5761 ttagacatga ctgccaaatc caaggtttga gcagttgtta aataagcatt agctgtcgcc
     5821 tccatgttgg gactggttac tttgaggcct actaaggcta gagatcccaa catcatcagg
     5881 atcaagatgg ataaaaaacg ccccttggag cctgtgaagg actgaattaa gtccttccaa
     5941 taagtttttc gcttgatcat gctagtactc caaactgtca atatcctgag gatgctggtt
     6001 gagcaccaca tccttgacac tggcatcgtg catatgaatc acgcgatcag caatgggcgc
     6061 caaagctcca ttatgagtca cgatgatcac cgtcgctccc ttttgacgag acatatcttg
     6121 gagaattttc aaaacctgct tgcccgtctg ataatccaag gctccagtag gttcatcaca
     6181 aagaagaatt ttaggatttt tggctaccgc gcgtgcaatg gagactcgct gttgctcccc
     6241 tccagaaagc tgggctggaa agttatttag acgatgagcc agacctacat ctgtcaagac
     6301 ctgatcagga ttcaaggcat ctgtcacaat ttcagaagcc agttccacat tttccttagc
     6361 tgtcagatta gaaactagat tataaaactg aaaaacaaac cccacatcat ttctacggta
     6421 attggtgcgc tggtgggaac tataatccgc aatattaaca ccatcaatcc agatttcccc
     6481 ttcatcattg gtatccattc ccccaagaag gttgagaact gttgacttgc ctgcacctga
     6541 agcaccaagg ataataacca gctccccctt ttcaatctca aaattcacat cacgattagc
     6601 cacaatctcc gtgtccccaa cctgataacg cttgtaacag tgtttcatct caatataagc
     6661 catcagaccc accctctatc aaacaaatta tactcctcga aaatctctct tcaaaccacg
     6721 tcagcttcca tctgcaacct caaaacactg ttttgagcaa cctgcggcta gcttcctagt
     6781 ttgtgctctt tgattttcat taagtattac ttcctattat cattataacg ctttttcaac
     6841 tagttggaaa ctgcctatat tcttaaatcc ttattaaaag gaagtttcaa attactgcct
     6901 tataacatct tcttaaaaat aaaattgaac aagatcacct tctgctgttg ccaccgaaat
     6961 acaatctttc cccatgcatt tcgcttttat tttttcttga ttcattttaa tcacactctt
     7021 ctcaatatct ggataagaaa ctcgcaaatc tcctccactc cttgataaaa tggtcaactg
     7081 taagagtttt ttatcttccc agctcatgct cacttcaaaa tgtccacgtg ccattaagcc
     7141 tgaaacaaaa cctgttgacc aagcatcagg tagggcagct agaggtacca gataagctgc
     7201 atgagactgg agtaacattt ctgccatgcc actagtagca ccaaaattac catctatctg
     7261 aaaaggagga tggctacacc aaagatttgg caaggtggat gtctttaact gctctgccaa
     7321 taatttatgg gctcaattgc catctcccaa acgcgcccag agattgatct tattagcctt
     7381 ggaccagcct gtgccgccat ctccacgatc attgaggcta gcacgcgccg cttcaatata
     7441 ctcttgtccc ttgtagctaa agagattgcc aggatagagt cccactagat gggaagcgtg
     7501 ccggtgctgg gcctccactt tctcattttg aaaatactgc tcttcctcct cataccactc
     7561 cctgattcga ccagattgag tgatttgcaa aggatttagt aaatcagact tctccttaac
     7621 ctcagtcaac aagtcctcat ccagtcccaa ttcctgagca gcctgaataa aatcatgaaa
     7681 taactgccaa atcagagatt ggtcataagt attgccaatc gaaatcggcc catgttctgg
     7741 ggaataagac ggagaagaca cccaacgctg cgcctgctga tccttatgta aaaaggcatt
     7801 ccaaaaacga accgtttccc tcaacatggg ataaattttc tccctgagat agtcttggtc
     7861 cctataaaat gaataggctt cataaacggt ttgcatcatc cacgcattgg cagctggtga
     7921 ccaaccccaa tagtaatccc aaccaggtgc cgtccaacca aagggagtcg cttgagtatg
     7981 aaccaaccaa ccattctcct cacctttctg agagacgatt cctgcatact ttacagccgc
     8041 tagacgacca tagacacgca aatcatctac atagttgatg actggaaaga ccgtctctag
     8101 aagattggta acataggctg gccaataatt catctgcaga ttgacattta agtgatagtc
     8161 cgaattccaa ggaggattgt cgaccgcatt ccagactccc tgtaggttag ctggtagagc
     8221 atctgggcag tctctggacg aactaatcaa taaataccgt ccatactgga agaacagctc
     8281 ctccaaagcc tgcccttctt gtggcttata attttttaac aaatcatctg tagtggatgc
     8341 gtcaacatca gcttccaaat ccaattgaac acgctggaat aaggcttggt agtcctcgat
     8401 atgccttgat ttcaattggg tatagccctt ttctttagct atgtccacca agtctatcac
     8461 ctgttgctct aaatctagtt tcttgcgata attgctagca ggattttggg caaaatccgt
     8521 cttagcggcc aagaagagat tggcataact ggctcctgat atctgaaccc tatctgacca
     8581 aactctaata tctccatccg tttcccaagc tagataacta gcaaaccgca gatcattatc
     8641 cttaactctt cccttcatca agatatgaga atcagtaata tccaacttac actccttgta
     8701 atcagatttt tcctgctcat actttccatc agaagccaaa tcacaggtca aggatagttc
     8761 tatagtaaaa tctagagttt ccaacccttc cttagtaaaa cattgaacca agagatcatc
     8821 tggaaaactc gcaaaagctt cacgttcaaa ttgcgttccc ttatagacat aagaagtcgt
     8881 cgcaagtgcc ttactaatat tcagctgtct ctgatagtcc gtcacctgag acaaagtcgt
     8941 accttgctgg ctgaactcaa tgtgaatatc cccaaaagac agataggtcc catattgact
     9001 cgtttttggc ccaattaggt gctgctcagc cagttcctta gccagattgt aatctctctt
     9061 ctccaaagcc tgccgaatct cagctaaaaa accatactga tcctgaagat ttccaccctg
     9121 ataatctgaa ctatcaggaa gtggacctcc agaccagaga cttttttcat taaattgaat
     9181 ccgttcagcc cctataaggc caaatacttt tgctcctaaa gaaccattgc ctatcggtaa
     9241 agcttcttct tcccaaccca tgtaagtggt tgaagctggt tgcttgtagg ccagtacata
     9301 atcttgtttt ttattcctta tcatacttcc atactaacat aaaaagccta gaaatcaatc
     9361 ctaggcttac aattttttat tttccaaggt aatattcaga aacgacgttc aatttttcgt
     9421 cgaattcgaa taccaatggt gggaagttag ggatttccac gtccatgatc tcgtcatctg
     9481 acaaaccttt gatgtgtttt acaagggcac ggattgagtt accgtgagct cctatgaata
     9541 cgtttttacc atctttaaga gctggagcga ttttatcttc ccagaatgga agagcacgtt
     9601 ccaaagtcac tttcaagttt tcagcatctg ggattactga gtcgtcaagt gaagcataac
     9661 gacggtctgt gtgagctgag tgctcatcat cacggtccat atttggaggc aatacatcgt
     9721 atgaacgacg ccagatgtga acttgctcat caccaaattg ttcagcagct tcagctttat
     9781 ttttaccagt caaaccacca tagtgacgtt cgttcaagcg ccatgatttt tcaactggaa
     9841 cccacaattg gtcagaagct tcaagagcca agttagttgt tttgatagca cgtttcaata
     9901 ctgaagtgta agcttggtca aatttgatac cagcttcttt gatcaattta ccagcgtcaa
     9961 tcgcttgttg tgtacctttt tcagacaaat caacatcagc ccaaccagtg aaaaggttag
    10021 ctttgttcca ttcagactca ccgtggcgag caaaaaccaa ttttaccatt agatggattc
    10081 tcctttaaat tttccgaggt ttcccctcgt ttatctattc tattttacac aatttttcac
    10141 aaaaaagcta gtcaaaacca aaaaggaaag gactgtttgg caatcacatt gtttttggtt
    10201 gtttctattc tatcttcatt atttaacctt tttttctgcg catcgaataa tttttgagtt
    10261 gactctttta gtttagtaaa cgagtcatta ttttccatag ctatgccttt gaaaccttcc
    10321 tcagctttag taaaataatc atcaaaaata tttttataaa gatctatata atctgcataa
    10381 gtgcgtattg attcaatcgc atcgtctgtt acaaccggtg tatcgaaagt gattgtttct
    10441 tttgaactat tggatgttgc tactgtcttc tcatcattac ttgttgaagt attctttgaa
    10501 ctttatgttc cacatgcaac tagaatagag atcctccgat aatagcaaga atccccccaa
    10561 cccatcctaa gaatggaatg agactaactc caccagaaac aatcattagt acagacggag
    10621 ctgcacctac acgcttatct cctttatagt aaacaatagc aatgatacca agaacaagat
    10681 ttgcaatctt caaggcattc aagagtaagg caacacctga aaaagcccct gcagtagctc
    10741 ctccattaag agttgtagca gctgtgttta ccgctgttcc caacaagaca aaaggaccaa
    10801 gtaagaagta aaattcctcc cacaagaccg acgataccac taattaaag
//
LOCUS       DAVLTT010000063        10758 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLTT010000063 DAVLTT010000000
VERSION     DAVLTT010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.063"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(117..1541)
                     /locus_tag="VYN15_001759"
     CDS             complement(117..1541)
                     /locus_tag="VYN15_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1453046.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2086..4365)
                     /gene="pulA"
                     /locus_tag="VYN15_001760"
     CDS             complement(2086..4365)
                     /gene="pulA"
                     /locus_tag="VYN15_001760"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV1453047.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4477..6435)
                     /gene="ligA"
                     /locus_tag="VYN15_001761"
     CDS             complement(4477..6435)
                     /gene="ligA"
                     /locus_tag="VYN15_001761"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV1453048.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6528..7706)
                     /locus_tag="VYN15_001762"
     CDS             complement(6528..7706)
                     /locus_tag="VYN15_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1453049.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEEAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLQSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7786..8649)
                     /locus_tag="VYN15_001763"
     CDS             complement(7786..8649)
                     /locus_tag="VYN15_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1453050.1"
                     /translation="MEHLGKVFRKFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEYSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8652..10553)
                     /locus_tag="VYN15_001764"
     CDS             complement(8652..10553)
                     /locus_tag="VYN15_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1453051.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3241 a         2364 c         1906 g         3247 t
ORIGIN      
        1 tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt tctataatta
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaattcct
      181 tgcactccag ctccagaacc tttgacacca aggaatggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag gagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt atctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaaag gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa ttttttcctt atcacgttct
     1321 aaaatagctg ctgttttatg caaataagcc gcacgttcaa ttgctgataa agctcgccat
     1381 gctggcagag ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaatcacaa ccctttttgc aaaatttttg
     1621 agattatttt cacaaacttg atttttcaaa gtatactcaa taaaaattaa aaaaatccac
     1681 tacgtcaagg cgaggctaat gtggtttgaa gaaattttcg aagagcgtga atgagtatca
     1741 tctatagtaa aataaaaaaa ctgaacaatt tggttgggga cagccaaacc aatttctcac
     1801 aatgtttcag aaacaagggt gtgctattcc aatttcagcc tactataact gtcatagatt
     1861 gctgaaacaa agtctaggta aaagtcttca taataaaaag acctcctatc aagtgttcaa
     1921 aaactttgat aggaggtctt gttttgtgaa aatatttatc aaattttcta tacaagtgag
     1981 ctgttagcca ggttctttct attctttcaa tttcaatgaa tggatttttt actaatactc
     2041 ataactggga atttgtctgt gtaaaaatag cgagatagat ggtatttata aaacactcaa
     2101 gacagctaga ctaatatcat ttaaaacatt atcttctttt gagcgactgt tggttaccaa
     2161 catagctaaa tttcctgcat tttcaaattg atagggttct gatttagcat tcacaaccac
     2221 caagaggtgt tctttgccgt gaacttcata gataaggtag ccgctatgtt caatcgcaga
     2281 atgcacaaag acatgatggt aaatttcatc atagctagag taagaaaagg caccagtttt
     2341 tgtcttcaat cggatgactt gacggataaa ctcaatactg tcttgacgct cattaatcaa
     2401 gttccagttc acttggttca cactgtcagg agcattatag ctattcatcg cacgctctct
     2461 atcatcatgg gtcaactcac cattttcacc agtcgcaacc agtttggtac gaccaaattc
     2521 ttgaccgatt tccataaagg ccatcccctg catgagcaga ttcatggctg tggcagtttc
     2581 gaccttgcgc atgatttgct ctgaactttg gtctggatga agggttgcca ataaatcgtg
     2641 aagattgtaa ttgtcatggg cttctacata gttaagcacc tgatttggat gtgtatagct
     2701 tcctaattca cgacttccta ggattgcttt agctagaatt ggctctgtcg cagcaccact
     2761 gacaaaacct gacttgatag caccataaac ttctccccct ttgacagcat cgcgctgatt
     2821 gtcattaaag aaaccaatat ttggcatctg gtaggcattg tccttcttgg ccttatcata
     2881 aggggcaaga cctgttccca tatcccatcc ttctccatag aggataatgt tggagtcgat
     2941 ttcatccaag ctttgacgaa tcatctgcat ggtcttgaca tcatgaatcc ccatcaagtc
     3001 aaaacggaag ccgtcaatat tatattcctg cacccagtat agaagagaat caatcatata
     3061 cttgcgaaac atttcgtgtt cactggctgt ttcatttcca acacccgttc cattctggaa
     3121 ggtaccatct ggattcatac gataatagta atcagggact gttgtttgga atggtgcatc
     3181 aacaactgag aaggtatggt tatagactac atccataatg actccaatac ccgcatcgtg
     3241 ataagcttga accatcacct tcaaatcacg aatgacctga gctggatcat ctggattagt
     3301 tgaaaaacta gtttctggcg cgttatagtt ttgtggatca taaccccagt tgtaggttac
     3361 atttccatcc tcatcgtatt ctttatgacg gtctgcaatt ggttgcaatt gaacataatt
     3421 gtagcccagc ttcttgatgt aatcaaaagc agttgactgg ccgtattggt taactgttcc
     3481 agcctgagca gcacccaaga aagttcctcg aagatgttca tctacacccg atgtaggtga
     3541 tttagtcaaa tcacgaatat gcatttcaca gataactgcc ttacatggat tttccaagcg
     3601 ccaagtagcc tccgaaccgt gcttaacctc gaagttttca acttgctttt ctacatggct
     3661 cagaatagct gaacgtttgc catcagggct ggtcgcgatt gtataaggat cacgtgtcag
     3721 tgtttggtga tgagggaatt ggacttgata ctgataagtc ttacctacca aatcttcttc
     3781 aacatccaaa ctccagacac cgattgtatt gtccttatga ttataagagt agctattgcc
     3841 tcttttcatc tcaaaagtct tccaaacggg tgcatcatta gcagctgatt cataaacgac
     3901 aacttgcact tctgtcgctg taggtgacca gagggaaaaa tgagcctgat tgtcctctac
     3961 acggcaaccc aattctcctt ggtaacccca atgatgatca aaactagcac tgttaatggc
     4021 cttatcaaag gcaaaaggat tttgattttt atagaaagga ctggcaatag caggattttc
     4081 agagtaataa atcctatcat cgccttccaa aatccagacc tctgttaata ggggatagtg
     4141 attaaaacgg atagaatatt ctttactagt ttgacctgta tgaaccacaa aattcaagct
     4201 ttctataaca tgtgaacttg ggtgttcaaa gctaaataaa gctccaaaat aatcttcttt
     4261 gtaggttagc aaatcaattc gttgatcctg actttttaca aaggagcaag tgtcatattc
     4321 tccattctta cgatggtaat gaatgcgcat agggtagtta tacatttttt atttttcctt
     4381 tttactttgt ttctatttca ctaataaatt tttgtcaatc tcgtctcaat taacagacat
     4441 agtcatattc tctaaactct gtttttaaac gatccattac aaactttcta gccatgcctc
     4501 atctctgacc tggataccaa gttcttgtgc tttttgcagt ttacttccag cgtctgcacc
     4561 taccacgacg aggtcggtct ttttagaaac actacctgtc actttggcac ccagactttc
     4621 gagtttactt ttagcttctg agcgcttgag tcgttccaat tttcctgtca ataccacggt
     4681 caaacctgac aaggccgcat ccgctactac cgtctgtcct ttatagtcca gattgacccc
     4741 agtttctttc aattctctga gcagaatttc agagccttct gtcgcaaaat aagtctgaag
     4801 acttttggca atcacgccac ctagactttc aatactagcc acttcctctg aatctgcctg
     4861 agacagattt tcaattgaat ggaaatattg aagtaaaagc tgactagcct tgcttccgac
     4921 atgacgaatt cccaaaccaa ataagagctt ctcggcagaa ttttcctttg atgcttggat
     4981 agcctgatac agtttagcag cggacttttc cttaaccccc tctaaaagga ggaaatcctc
     5041 ttcttgcaaa cgataaatat ccgccacatc cttgactaaa ttagcagcaa aaagcttctc
     5101 aacaatagat ggaccaaggc ctgtaatatt catagcatca cgagaagcaa agtgaatcaa
     5161 gccttccatg atttgagcag ggcaacgcgg attgatacaa cgtagggcca cttcatcttc
     5221 aaagtgcaac aagtcagagt tacaacttgg acagtttgta gggatatcta gtttttcttc
     5281 agaaacccgt ttggactcta ccacacgtaa aacggcaggg atgatgtcac cagccttata
     5341 tacaatgacc gtatcgtctt ttcggatatc tttttcagca atataatcta cattgtgcag
     5401 ggtcgcacgg ctaacagtcg taccggcaag ttgtactggt gttagattag cagttggagt
     5461 tacaacaccg gtacggccaa ctgtccagtc aactgataag agttgagctt ctttttcttc
     5521 agcagggaac ttgtaggcta ctgcccactt tggagcctta acggtaaaac caagttcttc
     5581 ttgacttgct aggtcgttga ccttgattac cactccatca atatcgtaag gtagattttc
     5641 ccgttcctgt cctacttctt ggataaaatt ccagatttca tctatgtttt cagccaagat
     5701 tcgcttagga ttgaccacaa aacctagttg ttctaggtac ttcaaaccct tttcttggct
     5761 atcacgagtt gaagggctgg cttcttgata gagaaacgtt gcaagattac gcttggcaac
     5821 tactgctgta tccaactgac gcagagttcc tgctgccgca ttacgaggat tagcaaattc
     5881 aggctctcca ttttcttggc gcacttggtt aacttggtca aaggaagcgc gtggcatgta
     5941 acattcccca cgaactgtga tatctagttc ttctggcaaa gtcaaaggga tgtccttaac
     6001 acgcttgagg ttttctgtga tattttcacc aattgaacca tctccacgtg ttaccccagc
     6061 aaccaaaatc cccttttcat aagtcagcga gatagataag ccatcgattt tcagctcaca
     6121 aatataggtc ggatgagcca cttccttacg aacacgcgca tcaaaagcat ctagctcctc
     6181 acgtgaaaaa gcatcctgca aactataaag aggatactga tgactgtatt tttcaaaacc
     6241 atctaaaacc ttgccaccaa cacgatgagt cggactgtct gctagcactt gctctggata
     6301 agcagtttct aactcgacca actcacggta aaggcggtca tactcactgt ctgaaaccga
     6361 gggattatcg ctggtatagt actcagtcgc atagcgattg agcaaagcga ctaactcatt
     6421 cattctttta ttcataagac cattttacca taaaacaagc cctcctcaca aacgagaagg
     6481 gcggaaaaaa cacttagttt gaaattattt ttgaaactca agcaacctta tatcaatttt
     6541 tcaaaatgag ttcgaacata aataaacgat atacaagaca agatgataac accacttcca
     6601 attatcagga aagaagagag atgtacactt tgcaagactg tcataaatcc ttttgcaata
     6661 ggcataaata gaatagctaa ggtaaaaatt gtactcagta ctctcccaag aaattcgctc
     6721 tcaaccttgg tttgtacttg agtaaaaaag tgaatattaa aaatcgtcat aaacaattca
     6781 caaactaaat ttccagaaaa ggaaagaaaa gttggaagtg gtaatcccat cataaaaact
     6841 ccgacacctg tcaaagccag taaaatcaaa agattataaa tattagcttt aattttacta
     6901 gctagaagag ccccaatgat ggaaccaata gcccccatag ttaaaatact tgcataggct
     6961 tcttctgacc cgtaaagctg attcgaaaag ggaagtagaa attcaaaagc tgcaaaaaag
     7021 aaattaacgc tggaagctac cagcaaaagg aagaaaattt cttgctgatg ccagatatag
     7081 tgtaacccat ccttgatatc tacaaaaata tctctcccag taaaagcctt tttctcttga
     7141 acttttgctt cctcttttgg aaggaaagcc actagaacaa aagcaatgaa aaaagtcagc
     7201 gagtctagca gtagcgtcat atggagactt gcaaactgta aaacaaggaa ggaaagaaca
     7261 ggagagctaa cacctacaac ctgcaaaacc agctctaagc gagaattata gatcacaatc
     7321 tcatctttct ccaccacttc agttatgata gctttattgg ctgtgcgaga aaaggcaaaa
     7381 gcaatagcct gcacaatgtt agcaacaatc aaagcgccaa tcatccagct atcattcctt
     7441 atgaaagaaa tagccagaca aagaatccca caaacaagat ctgccgtcat taaaatctta
     7501 cgacgagaaa aacggtctga aataactccg ccaaagggat tgacgagaat agatgtgacg
     7561 agctcagaaa tctgatacat tcctaaaact gtctgtccta tagtccccat agaagccaac
     7621 cagacactat ttccataatc atagagcata tttcccattt tattgatagc cccacggcta
     7681 atcaactgca ctgcatagcg attcatatta aagctcctct caaattttga aactattgta
     7741 tcaaaaccga aaggagcttt ttattttttc ccttatttgg gaaaattaac ttttgacaaa
     7801 tttttcgtag tgttcctgat aataggctac ttgctctgga agacctaaca catcaaaaat
     7861 atgcatggcc tcttgcatct gcttacagcc ttctttacac tgtccttttt gatataaggc
     7921 aaaacctttt aaataatgga aaacattacg ctcataaagc ttaatacctt tgtcaataat
     7981 cttctctgta taagcctcaa aatagttggc attataaaaa gaagaatact ctaaacaatg
     8041 ctggtaacaa ttgagggcca aaatcaaaac taatctctta tggcgactaa tctcttggta
     8101 aaattcctcc ctctccataa cttctctacc aatccgagtg acatagtcta catcgtagaa
     8161 actatagagg ttaccgaaaa gaatcaactc atacatggtc cattcttctg ttttgaagag
     8221 ataatctgct accttatcca aatcatcctg cttcatatca taagtcgcat ctctttgaca
     8281 aatcagacct tgtagcaaaa tccagttcag ctcaaaataa agggaagtcg tcgaactctt
     8341 agacttttca agttgttctc tttgaagctt ttgaaaacct gcaatatcgt ttgaatagta
     8401 aagtgggata atctgtgcca tcatagacac atgttcatga ttatgaaaat tccttgcctt
     8461 atccatgaaa ttttcgattg ttacatgaat gttatccaaa atctcaaaga aacgggagac
     8521 tgccaggtca gactccccaa gctcaaagcg agataactga gaggtagagc aggattcgcc
     8581 tgctgcttcc tttaaagaat aatttccact tgttcgaaat ttacgaaata cttttccaag
     8641 atgttccatc tttacacctg atctgataat tcttcccact caagcatagc ttcttcctga
     8701 cgatggctga ttttgtccag ctcagcctgt aattccatga gtttgtcggc atcgtttgtt
     8761 tccaacattt gttcagaaat ggcttggctt tgactttcta gctcttcaat ttcagcttct
     8821 agactttcga tttgtcgcat gagtttgcga acttcttttt gactttcttt ctgggcctga
     8881 tagtcattga ctggacttgc ttcctttgct tgattgctag ttgaagcttc ctcagtctga
     8941 ctcatttctg ctgttgcttt cttctcaaca tagtagtcgt aatctccaag gtagagagtt
     9001 gaaccattct cagacaattc caaaacatga gttgccacac gattgataaa gtaacgatca
     9061 tgactgacaa aaagcaaggt accatcaaag tcaatcaagg cattttctag cacttcctta
     9121 ctatcaatat ccaagtggtt ggtcggctca tccagaatca aaaagttatt gttttccata
     9181 gacaatttag ctaaaagcaa acgagctttt tcgccaccag atagcatgcc gactgatttt
     9241 ttaacatcat ctcctgagaa aaggaaggcc ccaagacggt tgcggatttc aacttctggt
     9301 gtcagtttga aatcattcca gagttcatcc agcaccgtat tacttggtgt cagcttgctt
     9361 tgggtttggt catagtaacc aacctcaaca ttagcgccaa agcgcttttc acctttgata
     9421 aaaggaatct ggtccacaat agacttgata aaggttgact tgccgatacc atttggacca
     9481 acgatagcga cagcattcat cttacgaaga tctaggttga taggttgtga caaaacttcc
     9541 ccgtcataac caatagcagt attttcaaca gtcaaaacaa cattgcccga cgttttttca
     9601 gactggaagg tcatgttggc tgctttcttg ccagcttcag gcttgtccaa acgctccatt
     9661 ttttctagtt gtttacggcg agattgagca cgtttggtcg ttgaagcacg aactagattg
     9721 cgattgacaa agtcttccag agcagcgatt tccttctgtt gcttttcata gttttttgcc
     9781 tcagtagcta gcttttgctc cttcaactca acaaaacgag agtaattccc cacatagcga
     9841 tccaaggaat gcttggtcaa atctagcgta attgtcgcaa ccttgtccaa gaaataacgg
     9901 tcgtggctga cgataatgag ggcaccgcta tagtttacca agtaattctc tagccaggag
     9961 atggtttcaa tatccaagtg gttagttggc tcgtccaaga ccaagagatt gggcttttca
    10021 aggagcattt tagctagagc caaacgagta ttttgaccac cagaaagctc agcaattttc
    10081 atctgccaca tagactcgtc aaacttgaat ccattcaaaa tcgctcgaat atcagcttca
    10141 taggtaaagc cacctgcttg gcgaaaattt tcagataagc ggtcataatc tgacatcagt
    10201 ttatccaaat cctcaccaga cttttcaccc atctccagct ccatctgacg cagttgttta
    10261 tctgtccgac gtaagtcatc aaagacatga agcatctcat catagatggt attttcagac
    10321 tcaaaacggc tatcttgagc taggtaagac agagaaatat cttttttctt attgatttct
    10381 ccactagttg gctcctcttc tccaactaaa atcttcaaaa gagtagactt acctgcacca
    10441 tttttcccaa caagggcaat ccgatctcgt tcatcaacct gcaggttgat attatcgaaa
    10501 agaacctctc ctgcaaaaga acgttcaatt ttattagctt gtaaaataat catacaagta
    10561 gtatagcatg tttccctaag gcattcaaga taatcgtaag tcttttagta caacttttat
    10621 aacataaaat aaactaaatt atgtatattt tatattagat tccttcacta tcttgttgga
    10681 ttttctaacc agctaatctt gtttcaaata gttatcgcac aagcctatta tttaattctt
    10741 ttcattattt acgtacgc
//
LOCUS       DAVLTT010000064        10443 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLTT010000064 DAVLTT010000000
VERSION     DAVLTT010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10443
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.064"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..380
                     /locus_tag="VYN15_001765"
     CDS             <1..380
                     /locus_tag="VYN15_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV1453052.1"
                     /translation="RGKVSGRRYQRISLVAGLTNGELIVPMTYEETMTSDFFEAWFQK
                     FLLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKK
                     HLKKVLPSCNTFYEALLSCSCFN"
     gene            280..726
                     /locus_tag="VYN15_001766"
     CDS             280..726
                     /locus_tag="VYN15_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1453053.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCPALVSIDYINCLSETTD
                     KNWHKSDRIFVTNIGKPVHSSILSKSLQRANERLKKPIPKHLPPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTQVTKNMKDEAINVLDKVMKKIF"
     gene            complement(864..2168)
                     /gene="eno"
                     /locus_tag="VYN15_001767"
     CDS             complement(864..2168)
                     /gene="eno"
                     /locus_tag="VYN15_001767"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV1453054.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2332..2778
                     /locus_tag="VYN15_001768"
     CDS             2332..2778
                     /locus_tag="VYN15_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV1453055.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2775..3890)
                     /locus_tag="VYN15_001769"
     CDS             complement(2775..3890)
                     /locus_tag="VYN15_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV1453056.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVANLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3899..4132)
                     /locus_tag="VYN15_001770"
     CDS             complement(3899..4132)
                     /locus_tag="VYN15_001770"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV1453057.1"
                     /translation="MISPQVKKETLEKWRKKLKLSKERTVAIGDGVNNLLMLKSAELG
                     IAFCAKEVLKKEIPHHVDKRDFLEVLPLIDCLE"
     gene            complement(4173..4544)
                     /locus_tag="VYN15_001771"
     CDS             complement(4173..4544)
                     /locus_tag="VYN15_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV1453058.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQLA"
     gene            complement(4603..6036)
                     /gene="glgA"
                     /locus_tag="VYN15_001772"
     CDS             complement(4603..6036)
                     /gene="glgA"
                     /locus_tag="VYN15_001772"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV1453059.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6033..7172)
                     /gene="glgD"
                     /locus_tag="VYN15_001773"
     CDS             complement(6033..7172)
                     /gene="glgD"
                     /locus_tag="VYN15_001773"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV1453060.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEHGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7162..8304)
                     /locus_tag="VYN15_001774"
     CDS             complement(7162..8304)
                     /locus_tag="VYN15_001774"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV1453061.1"
                     /translation="MKNKMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8294..10222)
                     /gene="glgB"
                     /locus_tag="VYN15_001775"
     CDS             complement(8294..10222)
                     /gene="glgB"
                     /locus_tag="VYN15_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV1453062.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFVERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3171 a         2295 c         1853 g         3124 t
ORIGIN      
        1 taagaggtaa agtatctgga agaagatatc agaggatttc tttggttgca ggtctaacaa
       61 atggtgagtt aatcgttcca atgacttacg aagagacgat gacgagcgac ttttttgaag
      121 cttggtttca gaagtttctc ttaccaacat taaccacacc atcggttatt attatggata
      181 atgcaagatt ccatagaatg ggtaagttag aacttttatg cgaggagttt ggtcataaac
      241 ttttacctct tcctccctac tcgcctgagt acaatcctat tgagaaaaca tgggctcata
      301 tcaaaaagca cctcaaaaag gtattaccaa gttgcaatac cttttacgag gctcttttgt
      361 cctgctcttg tttcaattga ctatataaat tgtctaagcg aaacaaccga taagaattgg
      421 cacaaaagcg accgtatttt tgttaccaat ataggaaaac cagttcatag ttctatcttg
      481 agcaagtctc tccagcgagc aaacgaacgc cttaaaaaac caattcccaa acatctgccc
      541 cctcacatct tcagacacac cactattagc atcttatcag aaaataaaat tcctttaaaa
      601 acaatcacgg acagggttgg tcattccgac tctgaagtca ctacttccat ctacacccag
      661 gtcacaaaga atatgaaaga tgaagcaatc aatgtactgg ataaagttat gaaaaagatt
      721 ttttaaaaag ttttgtccct tttttgtcct ctaaatacaa aaatagccct tcggataaaa
      781 tccgaggggc tagaaacgtt gttaaatcaa cggccgaact tttgaatttc atggttcggg
      841 ataaaatagt tcactgaact attttatttt ttaaggttgt agaatgattt caatccacga
      901 tattcagcta cttcaccaag ttggtcttcg atacgaagca attggttgta tttagcgatg
      961 cggtctgtac gtgaaagtga accagtcttg atttgtcctg cgttagttgc aactgcaata
     1021 tcagcgattg ttgaatcttc agtttcacct gaacggtgtg atacaacagc agtgtaacca
     1081 gcttctttag ccatttcgat agcttcaaaa gtttcagtaa gagtaccgat ttggttaact
     1141 ttgataagga ttgagttagc agcaccttct tggataccac gtgcaaggta gtcagtgttt
     1201 gttacgaaga agtcgtcacc aacaagttgt actttcttac caagacgttc agtaagagct
     1261 ttccaaccat cccagtcgtt ttcatccata ccatcttcaa tagtgatgat tgggtatttg
     1321 ttaaccaatt cttcaaggta gtcgatttgt tctgcagatg tacgaacagc agcaccttca
     1381 ccttcaaatt tagtgtagtc gtaaacttta cgttctttat cgtagaattc tgatgaagca
     1441 cagtcaaatc cgataaatac gtctttacct ggtacatatc cagcagcttc aatcgcagca
     1501 aggatagttt caacaccatc ttcagttcct tcgaaacgag gagcgaatcc accttcgtca
     1561 cctacggcag tttccaaacc acgtgattta aggattttct taagagcgtg gaagatttca
     1621 gcaccgtaac gaagggcttc tttaaatgtt ggcgcaccaa ctggcaagat catgaactct
     1681 tggaaagcga ttggagcgtc agagtgagaa ccaccgttga tgatgttcat cattggagtt
     1741 ggaagaactt tagtgttgaa tccaccaaga tagctgtaaa gtgggatttc aaggtagtca
     1801 gcagcagcac gagctacagc gatagacaca ccgaggattg cattcgcacc caatttacct
     1861 ttgttaggag taccgtcaag tgcgatcata gcacggtcaa tagcttgttg atcacgtaca
     1921 tcgtagccaa tgatagcttc agcaatgatg ttgtttacgt tgtcaacagc tttttgtgta
     1981 ccaagaccac cgtaacgaga tttgtcaccg tcgcgaagtt caactgcttc gtgttcacca
     2041 gtagaagctc ctgatggaac cataccacgt ccgaaagcac ctgattcagt gtaaacttct
     2101 acttcaagtg ttgggttacc gcgtgagtct aggacttcgc gagcgtaaac atcagtaata
     2161 attgacattt tttactctcc ttatgagtta aattttttac acctctataa taccttaaaa
     2221 cccctccttt ttcaagaaaa aacgttatct ttgtgcaact tttccttaac tttataaagt
     2281 aatcgctttc ttttgtctgt tttattccaa cttttatgat atactgtttt catgacagat
     2341 ttatcaaaac aattacttga aaaagctcat ggtgggttaa aaataaatcc ggatgagcaa
     2401 agacgctatc ttggtacttt tgaggaaaga gttcttggat atgtagatat tgacacagca
     2461 aatagccctc agttagaaaa aggcttttta tttattttag aaaaccttca ggaaaaagca
     2521 gagccactat ttgtgaagat ttcaccaact atcgaatttg ataagcaagt tttctactta
     2581 aaagaagcaa aagaaactga tagtcaagcc accatagtat ctgaagagca tattacttct
     2641 ccttttggcc tggttattca tagcaatgca ccagttcaag tagaagaaaa agaccttcga
     2701 cttgcttttc caaaactttg ggaagttaaa aaggaagaac cagccaaaac atccttatgg
     2761 aagaaatggt ttagctaaat cttgcacata tttaataagt gcccaatatt ggcagccgtg
     2821 cgctccagat agagactggc atttttcaaa ctatcttcta aaggttcact tttctctaaa
     2881 atagaaaaga cagcttggat attttcaaat ggtaggggag gtaaatcttc agcaagacta
     2941 ccgcaaatag caataacagg aactccaaca ggggttcttt ttgcaacacc tataggcgct
     3001 ttcccagcaa agctttgact atcaagtctt ccttctccaa caacaaccaa gtcagcatct
     3061 gaaactttct tatcaaagtt gattaagtcc aagcaggtat caattccaga cacgatactt
     3121 gcctgagcaa aggcacacaa accaccagca aggcctccac ctgctcctgc tcctttaatt
     3181 tctaatgttg caggtgagaa tttttcataa aaatcttgga tcgcctgatc tacgactgca
     3241 aacatagtcg gatgtagacc tttttgattg ccaaaagtgt aagtcgcacc ttgatgacca
     3301 cataagggac tcacgacatc tgctaaaata tgaatttgaa caccttcagg aattttatag
     3361 caattttctg ttgaaacaga agctaagttt aataaggatt gaccggaagc aggcaagaca
     3421 tttccatccc tatcataaaa ttgataacct aaaccagcag caatccccag tcctccatca
     3481 ttactggccg tgccaccaac accgatataa atatctttaa tccctttaga aatgagatgg
     3541 agaatcaact ctccaatacc acaagtttgg atttgaagtg gatttcgttt ctctagcgga
     3601 atttttccaa gaccaaccaa gttagctact tcaaatagtg ccagttcccc tttttgaaaa
     3661 tagcgcatgg cttctttttg tccaaaaggg tctgtcactt ggatccattt ttcttttagg
     3721 tcaagagaat gtcggatagc atctacagta ccttctcccc catcaccaac agggcagagg
     3781 agacattcta catctgctat cgattgttgg aagcctcttt ttattgcttc agctacctgt
     3841 tgagctgtca agctttcctt aaacgaatct ggtgcaatta caatcttcat attttccctc
     3901 attctaaaca gtcaatcaaa ggaagaactt ctaaaaaatc cctcttgtca acatgatgtg
     3961 gtatttcttt tttgagcact tctttggcac aaaaggcgat tcctaactcc gccgacttca
     4021 acattaatag attattgacc ccatcaccga ttgccaccgt tctttcttta gaaagtttta
     4081 gtttctttct ccatttttcc agagtctctt ttttgacctg gggacttata atttgtccaa
     4141 ctaattttcc tgttaaaaga ccttctttga cttcaagcta gttggcagtg aaataggcaa
     4201 taccaaggga ttttgctaat ctctccaact attggtgtaa atccaccaga caccagacca
     4261 actaggatgc cattcttttg gagaatagag atgaactctg ggacatttag cgatagatga
     4321 attgagttga agacgttatc aaagaccaaa ataggaagac cttccaacaa ggacactctt
     4381 tttcttaaac tgctttcaaa gaccaactct cctcgcattg ctcgacttgt aatctgcgaa
     4441 atttccgcct catgacctgc ctctctccct aaaagatcaa tcacttcttc taggattaag
     4501 gttccatcta catccaaaac acacaagcct tttacttgag acatcagttc tcctctctaa
     4561 acagcctaaa aatcgtatga agtcatcata cgattttatc tattaattaa ctaaactatg
     4621 gtacaagtca aggtatgact tgcaggctgt atcccatgag aagtcactct ccatagcttg
     4681 tttttgtagg tttctccaaa tgtctggatg gtttctatac aagtccaatg ctgtttggaa
     4741 agtccaattt aaccaataag gagatagatt gtcaaagcta aagccagtac cgcttccttc
     4801 gattggattg aaagcgcgaa ctgtatctcg caagcctcca acttcatgga ccaatggcaa
     4861 ggttccataa cgcatagcca tcatttgaga caagccacac ggttcaaaac gacttggcat
     4921 gaggaagagg tcacaagcag cgtagatttc ctgagcaagt ttgacatcaa aagtgatatt
     4981 tgttgatagc ttgtctgggt aaatctgagc aaaccatgag aaagctcctt caaaggctgg
     5041 atcgccagtt cccaaaagaa caatctgaac atcttcttgc aagatatggt gaagactttc
     5101 gaccaccaca tcaaaacctt tttgacgtgt caaacgagaa acaattccca ccagtggaac
     5161 gtctgctcta acaggcaagc caactctttc ttgcaatttt gccttatttt tggctttccc
     5221 agacaaatct tcctgattga aatgatagtc taaaagagca tccgtctgag gattataaag
     5281 atcagcatca atcccattca cgataccaga tactttacca gactccattt taagaatctg
     5341 atccaaatta catccaaact gactagtcat aatttcatga gcatagctag gtgaaacggt
     5401 tgaaacacgg ttcgcataga gaatacctgc cttcatccag ttcagacagt tgttccatcg
     5461 aagggtgcca tcagcgtaac gttcaaagcc aactccaaac aaatcaccca acattccttc
     5521 tgaaaattgt ccttggaatt ctaaattatg aatggttaaa actgtttcaa tgtcctcata
     5581 ggcttgaatc caacggtatt tttccttcaa caagaaagga atcatagctg tatggtagtc
     5641 atgaacatgg agaagatcag gaataaagtc aatcctttcc atagcctcaa tggcagccag
     5701 ttggaaaaag gcaaagcgtt ctccgtcatc aaaatcaccg taaacatgac cacggaagaa
     5761 ataatattga ttgtcaataa agtagaaggt tacaccattt aatactgttt tcttaattcc
     5821 acaatactgt ctgcgccaac caacgctcac ctcaaaatga agcacatctt caatctgatt
     5881 tccaaattta gcctctacca tatcatagta gggtaaaatc actgcaactt cgtgcccagc
     5941 ttttaccagt gattttggaa gagcgccaat gacatctccc aaaccacctg tttttgaaaa
     6001 gggtgcaccc tctgctgcta caaataaaat tttcatgaat gaatatcctc tgttacttta
     6061 gcacctttct taaccacaac tggatgttct gcagttcctc gaatcacaac accatgctca
     6121 acttcaaccc ctttgtccaa gatagcatat tcgacctgag ccccttctcc aataacaaca
     6181 cgagggaaga gaaggctatc tttaaccaag ctatccttat ggacatgaat attacgtgat
     6241 agaacagaat tagctacttg accttcaata atactaccag aggcaaactg agaagtgctt
     6301 accttagatg tattagcata gtaagttggc tcttcgtttt tgacctttgt ataaatcttt
     6361 tggtttggtg agaaaagaga atagaatttt tgtgattcaa gcatatcgat attcgcttga
     6421 taataagatt taacagagtg aatattggct agatagcccg tgtactcgta ggcgaaagct
     6481 ccctctttta cagccaaatc ccgtaaaaca tagcgcaatt tctctggatg ttctttttta
     6541 gcttcttctt ccaagtgttc aatcaaccaa ggtgtatcaa cgacaaagat atctgtagac
     6601 atattgaacg tttcagctgt tgacttgcta tcaaagagtt tatgagaaag aacatggtct
     6661 gtttcatcta catccaagat tgcatttact tctgaaatat ctttcttagc tagtttttta
     6721 taaactacag tgataggctc ttttgttgta ctatgtaggt ggaaaacttg gttcaaatca
     6781 atgttaataa gaacatcgca gttgagggca accgtttggt ttgagccaga acgtttcaaa
     6841 taagtaagaa gctgttggta gtattctttt ccaactgtac tactttctac acgggtattg
     6901 taaattccta gatagtaatg gctaagaagg gttgataagc cccactcgcg tcctgaacga
     6961 atatggtcaa atactgagct gatattatcc tgctggaaaa taccaaagac actacgaaca
     7021 cctgcattag caaggcttga aagtgggaag tcaatcaaac gatatttccc accaaatggc
     7081 aaacttgcta ctggacggtg gtccgtcaat gtcgacatat tgtgaaaacc aactgtattt
     7141 cctaaaatgg cagaatattt atcaatcttc atctgttgct acccccacta cttcattata
     7201 tcctacaact tgtacttcat ctgttccatc aatttcgaca ccgtcagaaa taatcgcacc
     7261 ttcaccaata atggcacgtt taatcttagc tccttgacca atgatagctc cactcatgat
     7321 aactgaatca aggacttccg ctccttcgcg aacttgcgcg cctgttgaaa ggatagaatg
     7381 tttaacagtt ccatcaacga aacatccgtc tacaactaat gagtcttcca catgagcatt
     7441 tgccccgagg aagtttggtg gtgaaatcaa gtttcttgag taaatcttcc attgacggtt
     7501 acgactatcc aaggcatttt ctggagaaat atactccatg ttcgcttccc aaagtgactc
     7561 aatagtacca acatctttcc aataaccact aaattcgtaa gcataaacac tttcacctga
     7621 ctcaaggtaa tttggaatga catttttacc aaagtctgac atgccaacct tgctcttttc
     7681 agcagcgact aacatattac gaaggcgttg ccaatcaaaa atgtagattc ccatagaagc
     7741 ttttgtagat ttaggttgag ctggtttttc ttcaaattca acaatacgat tgttagcatc
     7801 tgtgttcatg ataccaaaac ggcttgcttc tttaagaggg acgtctaaaa ctgctactgt
     7861 caagctggca ttattatcct tatgagactg gagcatatca tcatagtcca ttttgtagat
     7921 gtggtcccca gacaaaatca agacatactc aggattgaca ctgtcgatat agtcgatatt
     7981 ttggtaaata gcgtgactag ttccctcaaa ccaacgattt ccttcacttg cagaataagg
     8041 ttgaagaata gagacgcctg aattaatacc gtctagtccc cagcttgaac cattcccaat
     8101 atggttgttg agagcaagtg gttgatactg tgtaacgacc ccaacattat gaatccctga
     8161 gttggcacag tttgataggg caaagtcaat gatacggtag cgcccaccaa attgcacagc
     8221 tggttttgcg atgctttgag tgagtttacc gagacgagtt ccttgcccac cagcaagaat
     8281 caaagctaac attttatttt tcattttcta ctcctttttg gtttttattt gtgacggttt
     8341 tagtagattt caagcgacgt ttgattttcc atacacttgc tcccatagcc ggtagagtaa
     8401 aggttaaggt ctgctcataa tctttccata ggccttcttg cgtttgaaca gtttgattat
     8461 gttctttcca aacgcctccc cactcttcca actcagtatt ccatacttct tcgtaaattc
     8521 ctgcaacggg tagtccgatt gtaaaatctt tccgctcaac aggtaccatg ttaaagatac
     8581 agactaacat ttctcccttt ttacccttac gaataaagga aagaacactc tggtctcgat
     8641 tatccgcatc aatgatttca ataccatcat agctggtatc gatttcccac agacagcgat
     8701 gatctttgta aaactggttt agctgagaag tgaaatactt catcttagca ttcattgggt
     8761 cttctaggtt agaccattcc aactgttctt cagatttcca ttctaggaat tgaccgtatt
     8821 cgctacccat gaagagcaat ttcttaccag ggtgacaaat ttggtacgta tagagattgc
     8881 gcaagcctgc gaattgattg taacgatctc cccacatctt atgcatcata ctcttcttgc
     8941 catgaaccac ttcatcgtgc gagaatggca agagataatt ctccttgaaa acatacataa
     9001 agctgaaagt caccaggtta aagtcatatt tacgataaat cggatcttct tcgtagaaac
     9061 ggaggatatc attcatccag cccatgttcc atttgtagtc aaatcctaga ccaccaatct
     9121 ctttcattcc cgtaatcttg gtcgcagacg aactttcttc tgcaatcatc atcacatctg
     9181 gatattctaa cttaataact tcattcaagc gttgaagaaa ataataacct tcatagttaa
     9241 gatttccgcc atctttatta ggtgtccatg gagcattatc atagtccaaa tagagcatgt
     9301 tgctaacagc atccacacga ataccatcca aatgatagac atcaatccaa tgcttaatgc
     9361 aagaaattaa gaaggactgg acttcatttt ttccaaggtc aaaattaagg gcaccccaac
     9421 catggttatg agccttatta tggtcttggt attcaaaagt cggtgtccca tcataatagg
     9481 ctaaggcatc atcgttgatg gtaaagtgac ctggtaccca gtccacaata accccaatat
     9541 tatgggtatg acactcctcg acaaaatctt gaaactcctc tggtctgcca taagcatgct
     9601 ctaaagcgaa gtaacccata agctgatacc cccaactcaa gcccaaagga tgggacatca
     9661 agggcataaa ctcaatatga gtatagttca tttcaacgag ataaggaatg agttcatcct
     9721 tgagctgggc aaaactataa ggactgccat caggatttct cttccaagag ccagcatgaa
     9781 cctcgtaaat attgacagga cgttcaacaa agccccaacg ttttcttcgt gccagccaaa
     9841 gtccatccct ccatttctta tcaggaagct ctgttacgat tgcccctgtt cctggacgag
     9901 cctcatacct gacagcaaaa gggtcaatct tcatcagttg atgaccattt tgacgtgtga
     9961 catgatattt gtaaatatgc ccttcttgag ccatattggt aaagacttcc cagaccccaa
    10021 agtcatttct taccattgga atctgatttt caatccagtt ggtaaaatca ccaaccaagt
    10081 gaacagcctg agcattaggt gcccaaacac ggaaggtata gccatgctct ccatttagtt
    10141 cttccctatg tgctcctaga taatgttgga gataaaaatt ttcacccgtc ataaaggttt
    10201 ttaatgcttc tctattatcc atatactccc cttctcctgt aagcgttttc tatgttttta
    10261 ttatactacc tttttagaga agattcaagt aaattactat acttctttaa ttattttgaa
    10321 aatctacaac aagttcactt actcgttcaa ttgtaaatca atattttttc aaaaaattgc
    10381 gaaaacgcct ttctttttct actatagtga aatgaaataa aacatgcgca aatcgatcag
    10441 gac
//
LOCUS       DAVLTT010000065        10302 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLTT010000065 DAVLTT010000000
VERSION     DAVLTT010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10302
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.065"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(8..1222)
                     /locus_tag="VYN15_001776"
     CDS             complement(8..1222)
                     /locus_tag="VYN15_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1453063.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1378..1660)
                     /locus_tag="VYN15_001777"
                     /pseudo
     CDS             complement(1378..1660)
                     /locus_tag="VYN15_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1731..2183
                     /locus_tag="VYN15_001778"
     CDS             1731..2183
                     /locus_tag="VYN15_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV1453064.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2218..3606)
                     /locus_tag="VYN15_001779"
     CDS             complement(2218..3606)
                     /locus_tag="VYN15_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1453065.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3672..4634
                     /locus_tag="VYN15_001780"
     CDS             3672..4634
                     /locus_tag="VYN15_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV1453066.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLIVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAKKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4930..5940)
                     /gene="ccpA"
                     /locus_tag="VYN15_001781"
     CDS             complement(4930..5940)
                     /gene="ccpA"
                     /locus_tag="VYN15_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV1453067.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6365..6964)
                     /locus_tag="VYN15_001782"
     CDS             complement(6365..6964)
                     /locus_tag="VYN15_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1453068.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(6966..8063)
                     /locus_tag="VYN15_001783"
     CDS             complement(6966..8063)
                     /locus_tag="VYN15_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1453069.1"
                     /translation="MLERLKSIHYMFWASLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VEQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMCEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     DSMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(8063..8800)
                     /locus_tag="VYN15_001784"
     CDS             complement(8063..8800)
                     /locus_tag="VYN15_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1453070.1"
                     /translation="MKRWIALSKIEFLLIKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GEPANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(8802..9686)
                     /locus_tag="VYN15_001785"
     CDS             complement(8802..9686)
                     /locus_tag="VYN15_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1453071.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADCILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(9673..9867)
                     /locus_tag="VYN15_001786"
     CDS             complement(9673..9867)
                     /locus_tag="VYN15_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453072.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIHGALGFGFM
                     IFVVFPMGMEWLKGESHDCG"
     gene            complement(9864..10070)
                     /locus_tag="VYN15_001787"
     CDS             complement(9864..10070)
                     /locus_tag="VYN15_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453073.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         3139 a         2359 c         1879 g         2925 t
ORIGIN      
        1 gcaagcccta tctacgatac tgtttcaaga aacgagtcat cttttcttgg atttgggcta
       61 actcatcaac acgaggaagg taaacgatac ggaagtggtc tggttcctgc cagttaaagc
      121 ctcgaccatg aaccaagaga accttttcct gcttcaagaa atcaaggaca aactgctcat
      181 catcatcgat acggtacata ttgcggtcga tttttgggaa gatatagagc cccgccttgg
      241 gtttaacggc agacaaacct ggaatatctt gaatggcatt atagatgaaa tttctttgct
      301 cgtagattcg tccaccagga agaagcaatt catcgactga ttggtgaccc cccaaggaag
      361 tttgtacgac ttgttgggcc aaaacgttag agcaaaggcg catattggac agcatattga
      421 gcccttcgat atagccctta acatgagtct tagggccaga caagaccatc caacccacac
      481 ggaaacctgc tatgcggtgg gattttgaca gaccattcat gctgacacag aagacatctg
      541 gtgccaagct cgccacaggc gtatgcacat gtccgtccat taccatgcgg tcatagattt
      601 catccgcaaa gataatcaaa tcgttttgac gggcaatctc aataatctcc agcaagagtt
      661 ccttaggata aagggctcca gttgggttat ttggattgat aaggacgatt gccttggtat
      721 tggaagtgat ttttgacttg atatcgtcaa tatctgggta ccattcaaca gcttcatcac
      781 agatatagtg aacggcattt cctccagcta ggctgacagc cgccgtccat agaggatagt
      841 ctggcattgg cactaagacc tcatccccat tgtccaaaag cccctgcatg gacatgacaa
      901 tcaactcact gacaccattt ccaaggtaaa tatcatcaat atctacgttt gggaatttct
      961 tcagctggca atactgcatg atggccttac gggctgagaa aatccctttg gagtcagaat
     1021 agccttcact atcacgcgca ttcataatca agtcatgaat gacctcgtct ggcgctgtaa
     1081 agccaaattc tgctggattt cctgtattca gacgtaaaat cttttctcca ttcgctcgca
     1141 tccgcatggc ttcttccaat acaggaccac ggatatcata agcaacatgc tctaacttac
     1201 tagacttgtt atattctttc atcttgtttc ctcaattcat caggatagta acattatacc
     1261 actagaaaga gaatgcgaca agtttactga aatgtgttac tagtttcgta tagaagaaaa
     1321 accttgctaa aggcgaggtt aagaacgtag agatagcagg tattttgcaa agacacatca
     1381 cataccaaaa gataaaccta gaaaaaagca agcctagaaa ggagtcataa agaagattaa
     1441 acatgaggaa aagcccccat atcatcaagt aatcccaacg cccacttcgt tttacaacta
     1501 gaaataagat tagatggtag agtacatgaa agactaaaaa tccaataaaa cttggataaa
     1561 gaagcggtac cagactctct aattgccaga tcatgatcac ttctaccaag actgaaacta
     1621 ggataattcc ataataaagg aaatttgatt tttgaaaaat actttttttg ctttacttct
     1681 atagtgaaaa ggtttacaat tatagtaaga aaatttcagg aggtttcatt atggcacaac
     1741 gttaccaaaa tatcatggtc gcaatcgatg gttctaagga agcggacttg gcttttgtca
     1801 agggagttca ttctgctcta cgaaacgacg ctaaactcac catcgcacat gtcattgaca
     1861 cacgcgctct ccaaagcgta tccacctttg atgctgaagt ttacgaagaa ctccaagtcg
     1921 acgctgaaag tctgatgaaa gagtacgaaa aacgtgctaa agatgctggg gtagcagatg
     1981 ttcatatcgt cattgaaatg ggaaatccaa agaccctgct agcacgtact attccagatg
     2041 ccgaggaagt ggacctcatc ctcgttggcg caactggtct caacgccttt gaacgcctct
     2101 tggtcggctc ttcatctgaa tacatactcc gccatgctaa ggtcgatttg ctggttgtga
     2161 gagaacaaga aaaaacctta taatcacaaa gaaaaggagc ccctagctcc tttttgttta
     2221 cgatttattt ctctctttat ggcgttcgta agccttgagc tggcgctgca gttccttttt
     2281 aatagcaggt tctggagcat atttttcttc ccaattatct ggttttaaga ttttatgggt
     2341 cactggatca aaatgagcct tgccatctgg aaaaattttc cccatattgg cctgatggac
     2401 aatatcaaaa atacgttctg ggtccacccc catcaagaca aaactgccgt aggtgaagta
     2461 aagcgtgtca atcaaggcat ccacttgccc tatcaaatct tgctgagcag gtgtcttctt
     2521 ggctacttta cctgctgcct tatcaagggc ctgatgaagt tgcgatacag cttgaccaaa
     2581 atcttcttca gaaggactgg ctgctcgaac aaactccacc aattcttcta ttttaaaacc
     2641 agccctatgg gttgcaccct ctaaatccca agctcgaggt tcttcttggg ttcgttcatc
     2701 catcatgtgg tggaaggtct tgaccttatt gaaatgatag tcacggctga caaagacttt
     2761 ttctgaagac aaaacaccaa aatgttccaa ggccttgtgg atcccatctt gttgattgct
     2821 agtggtaatg tgcttggcag cttccttgac actgctacta ccatttccca tagcgaccga
     2881 cataccgacg ccagccagca tttcaaggtc attatctgag tcaccaaaag ccatgacttg
     2941 gttgaggtca aagccatatt ctttcccaac tcggcgaata ccttctaatt tagaatttcc
     3001 ctgattgatg acatccgatg caaaaggatt gctacgtgtc aatttcaagt cttcaaaatc
     3061 agctgccgcc ttctcagatt cttctggtgt catcagcatc aaaacttggt agataggctg
     3121 attcatcagg tgaagcaggt cctcttcctt ttggggaaca accttgctga ccatgcgatt
     3181 aaaagactga ctcaccgtcc gagttaaaac agagggaacg aagcgactaa ttcgttggga
     3241 aaaagaaccc agaccaaagg acatgatttt agaacccaac atggcatcct tggtccctag
     3301 agcaatctcc gtgccctctt ttttagcata gctaattaga tggcgcaaat gtaacttgga
     3361 aatagggctc gtgaacaaga ctctgtcttt actaaagata tactggccat tataggttac
     3421 cgcaaaatcc agatccaaat cgtccatcaa ttccttaaca aaaaaaggtc ctcgccctgt
     3481 cgctacgcca actagtaccc cttgttcttt gacaatctta atcgcgtcct tagtggattt
     3541 caaaacactc ttgcgattgt tgaccaaggt tccatcgata tcaaaaaaaa cagctttgac
     3601 ttccatccta ttccaatctc cccttttgtg atacaatgat tataccacat ttcagaaaga
     3661 gttagtaaat catgcctaag aaaatccttg ttttacatac gggtggaact atttccatgc
     3721 aggccgatgc ttctggcgct gttgtgacga gttcagataa tcccatgaac catgtgtcca
     3781 acccacttga aggaatccaa gtccacgcct tggacttttt taaccttcca agtccccata
     3841 tcaaacccaa acatatgctg gtcctctacc agaaaattaa agaggaagca gataactacg
     3901 atggagtggt gatcacacac ggaaccgata ctttagagga aacagcctat ttccttgata
     3961 ccatggaagt tccccatatg cctatcgttc taacaggagc catgcgtagc tccaatgaac
     4021 tcggtagtga tggtgtttat aattacctaa gtgctttacg agtggccagc gatgacaggg
     4081 ctgctgacaa aggagttttg atcgttatga acgatgaaat ccacgctgcc aagtatgtca
     4141 ccaaaacaca tacgactaat gtcagcacct tccagactcc aacacatggc cccctcggtc
     4201 tcatcatgaa acaggaaatc ctctacttca aaacagctga acctcgtgtt cgctttgacc
     4261 ttgatcacat acaaggttta gtccctatca tctcggctta tgctggtatg acagatgagc
     4321 tgattgatat gctggattta gaacacttgg acggtttgat tatccaagcc ttcggagctg
     4381 gtaatattcc caaagaaacg gctaaaaaat tagaaagcct tctgcaaaaa ggaatcccag
     4441 tcgctctggt atcacgatgc tttaacggta ttgccgagcc tgtttatgcc taccagggtg
     4501 ggggcgtaca gttgcaaaaa gcaggcgttt tctttgttaa agaactcaac gcccaaaaag
     4561 cccgcttgaa actcctcatc gccctcaatg ccggactaac aggacaggct ttgaaagact
     4621 atatggaagg ctaatactct tcgaaaatct ctgcaaacca cgtcacgtcg ccttaccgta
     4681 tgtatggtta ctgacttcgt cagtttcatc tacaacctca aaaacatgtt ttgagctgac
     4741 ttcgtcagtt ctatctgcaa cctcaaagca gtgcttttag ctgacttcgt cagttctatc
     4801 tacaacctca aaacagtgtg ttgcgcagcc tttaaccagc cgcctagtcc gctctatggt
     4861 attcattaag tcaacatctc ttgtttaaga gcacaaaatc aggaaatctt ctcgattccc
     4921 tgattttttc tatttacgtt ttcgtgttga gctacgttct gtcaaaccat gaggtaagag
     4981 aacttcacgt tcttccaact cttccttatg cataatcttg gtcaacatac gcatactaat
     5041 ggcaccaagg tcataaagag gttgggcaat cgttgtcaag tttggacggg taaagcgtga
     5101 gatttgtgaa tcatcactag taataatttc aaaatcttct ggcacagaaa cacccttatc
     5161 agccaaaccg ttcaagactc ctgctgccaa ctcatcacct gtcacaactg ctgcagttgc
     5221 atttgatgaa atcaaacgct ctgctaaggc gtaaccatca tcatagctat atttagattc
     5281 aaataccaaa ccctcactat aagtgattcc tgcttttttc aaggtttcct tgtagccaac
     5341 taaacgaacc ttaccattga tgtcatccac tagcggaccg ctaacgaaag caatacgctc
     5401 attttcttta gcaaggtaac tcactgcatc aattgttgct tgcttatagt caatattgac
     5461 actgggcaac tggtgctcaa catcgacagt tcctgcgaga acaatcggag tacgtgaacg
     5521 cgaaaattct gagcgaattt tatctgtcaa gtgataaccc atatagataa tgccatctac
     5581 ctgctttgaa aagagggtat tgacaacaga aacttctttc tcgttatctt catcgctatt
     5641 agctaggaca atattgtact tgtacatttc tgcaatatca tcaatcccct tagccaaact
     5701 cgaaaaataa ccattggtaa tatttggaat cacgacaccg acagtggttg tctttttact
     5761 tgcaagacca cgcgcaactg catttggacg ataatccaaa cgatcaatta cctctagcac
     5821 ttttttacgg gtattctctt ttacattttt attgccattg accacacggc tgaccgtcgc
     5881 catggaaaca cctgcttcac gagcgacatc ataaatggtt actgtatcat ctgcattcat
     5941 tccttttcct gtcctttcta tctcacacat tcttttacaa gtagaggtac tgattgaagc
     6001 tctatatcta cttacaaaag tgaagatgtg aaaatttcgt tttcatattt ctacttattc
     6061 cattctatca ctaattgtaa acactttcaa gtgttttttg aagattgatt gaaaaaattt
     6121 catagaaaac ctaggtttag ctccttgcta ccaccttaga ctaaacaaaa aggaggaaac
     6181 taagccctcc taaagttata gtaaaatgaa ataagaacag gataaatcga tcaggacagt
     6241 caaatcgatt tctaacaatg ttttagaagt agaggtgtac tattctagtt tcaatctact
     6301 ataggtattg ttccattcaa tcccatcaat tttagcacat aatggttttc gagatatgat
     6361 agtattacaa ccaaccagat tcttttgcga tattagctgc ctctgttcga ttacctgcat
     6421 ctagtttcga aagaatatta gtgacatagt ttcgaatagt tccgtttgag aggtaaagct
     6481 gatctgcgat ttcttggttg gataagcccc gggcaattcc ctttaagaca gcaatctctt
     6541 gttctgtcaa cggattggga cgggtcatca ccacttccat caattcaggt gaatactcct
     6601 tgcgtccttc gaggacggtg tgcaaggttt gcatgaggtc tgcaatgctt cgttccttta
     6661 atacataagc atccactcca gccttgaccg cacgttcaaa atacccagca cgcttgaagg
     6721 tcgtcaccac aaccaccttt gtttcaagcc tttctgatcg tatccactcc aagacttcaa
     6781 gacctgtctt aacaggcatt tctacgtcaa ggatggcgat atctacagac tccttttcta
     6841 atagttggat tgcttcttgc ccattcttgg cttgaaggac agactccaca tctggttgaa
     6901 gcgtgagcaa ttgacacatg gcatctcgca acatactttg atcttctgcg actaatactt
     6961 tcatcttagt ttctctcctt ataaggtagt cgaacttgca cttccgttgg atgtttctga
     7021 ctgattacac ttacttctcc tgaaaatgga aaaacacgat ctcggactgt atggagctca
     7081 tctcctttta gaaaagcaaa gccgcagcca tcatcactta ctgttaaaat gagttccttc
     7141 tctgtccgtt ctaattttaa gtaagcttta gacgctttgg catgtttgat gatattggtc
     7201 accaactcaa gcaaaatcat agaagccatt gaatccaatt cttgagtaag gctagcagta
     7261 tctagttggt tatctgtttc cacctcaatt ccagcaattt ctaacatctt tttcacagtc
     7321 tctagttcgg atgtcaaagt tctagactta agattttcca caatggttcg aacttcacac
     7381 attgattctt tgctaatttg ctgtatttct cttaattcct tttccacttg tggataagcc
     7441 tgcatttgaa atagctgcaa ggctagatct gtcttgacac taagcatagc aaaggtatgt
     7501 cccagactat catgcaaatc ctgaccgata cgattgcgct cattttctgc tagcaataga
     7561 tttatctggg tattttgctc gacctgagct tctttcaaat cctcgacaag gcgaattcga
     7621 accgagccca aagtcatcaa atcgacaaaa gtaagaatta caagcatata gactagaaac
     7681 tcaacttcga ttctctgaaa aatcaaaagt cgccccacaa caaggacttg agcaaggaga
     7741 aatgtccata catgtaaaga ctttaaacta cgtacgccaa aatgataaat taagagattg
     7801 gaaaggaaaa agaaaaacca gatataattc ccagcaacaa aggcggtatt cccagctaca
     7861 tagaccagca tgatccccca gaaaagccaa gataggcgct ggttcttagt tattaaaaca
     7921 cccaaatacg tcactacaaa tagaatatca accaataaat gccaagcagg aagctcccca
     7981 atcactacag gtaggatggg aaaaagcata aaaatcaaac tggcccaaaa catatagtgt
     8041 atgcttttca gtctttcaag cattaagcat tctccttatg accttgaagg taaatagtca
     8101 aaccaaataa aactgctgaa aaaacaagta aataaactgt ggctgataga ttgatgccac
     8161 cctcgtttaa gaaggtcttg agcaactcca tcaattgata ggtcgggaga cacttaccaa
     8221 ctgcttgcat ccagtctgga aataaagaaa tgggcatcca gagtccgcct aaaacagcca
     8281 atcctagata aagaagattg cccacaacag acatcagctg actagttggt aagagagtca
     8341 aggtcaagcc aagtgctaca aaagcaatac tccccacaat cagcaaaatc gcagctccaa
     8401 cccattttac tagaggcatg tctacacctc ttacaaaatg tccaactgta aaaacaacca
     8461 gaattgagac caaataatca accagcatac ttgttatctt tgatagataa tattctacca
     8521 tatttacagg gctatgacgc aatgttttct gccagttatt catcttatcg gtatgtaaaa
     8581 cagctggaaa tgagaggata gttgtcgaca tcatggaaaa ggcagtcatg gagatgaggt
     8641 aatcacgcat aaaattcgcg ggttcacctg gtgtgtcctg atagatacca gaaaaaaata
     8701 aatagaaagc cgtcggcatc cctaccgaca atagataata gattaattgt cgtttgatca
     8761 ataaaaattc tatcttacta agtgctatcc atcgtttcat cttagttatc tcccttctgc
     8821 gtctcttcaa agattgtatt caacaaacta cgattattaa cttcgatttc ttgcatccta
     8881 catcctgctt gggctaatag ttcccagaaa gcatctgctt ctcgagtgac tacttgtaaa
     8941 gaatcttgct ttagggtcca gttttcaacc aaatttgact gctctacgac ttccttgtaa
     9001 gctataggaa ggataaagtg cttttctatt tcctcgctac gcatagctag aggcgtcgta
     9061 tctcgaatca actctccctt atttaagagc aaaatgcagt ctgcagtgtg ttccacttcc
     9121 tcaatataat gggacgaata gagaatggtg actccttgcg cttttaactc ctggacaatt
     9181 tcccaaaaac gttgacgagt tgaggtatcc atggacgcag taggctcatc taaaaaaaca
     9241 atctttggtc gcccaattaa ggtcaagacg aaagaaaaga gacgcttttg accgcctgat
     9301 aatttttctg ccaactgttc tttttgttgc ttgacaaact gcaatagttg atcaatttcc
     9361 tgattgctca aaggatttgg atagatacgt tgaaagaaag caatcaactc tttaactttt
     9421 aatttctgaa cgattacatt ttcttgaggg aggtaagccc tagtatagtc taacttagaa
     9481 ctcgtcactg gtaaaccttg aatagatact tgaccgcttg tgaccagttt atctccaagc
     9541 aaacaatcta agagtgttgt ctttccagca ccatttggac caattaaggc aacacattca
     9601 ccatcgttga tttcaaagga gatgttccgc aaaatttcct tgtcttttat tttcttactc
     9661 aatttttcaa ctttaaccac agtcatgaga ctctcctttc aaccactcca ttcccatagg
     9721 gaaaacgacg aaaatcataa atccaaaccc caaagcacca tgaatgaatt ggcgaagcaa
     9781 ggcttgatca aaccaatcag taaacatttc cactaaccat accaagagtg acaggccgat
     9841 aaagaaatag atgatccctc tcttcattct tcaaactcct ttttcacatc tctgactaat
     9901 ttcaaacctt ctctaacaag ccaagacatg attccaaagc cagcaaagac cttccaagga
     9961 aaatggtaga aatcctcatc caatcccgaa aacatgagat aggtcataac tcctgctact
    10021 actaaactca ttgcaataat cattttattt ctcatctctt cttcccccat ttcatactac
    10081 aattatagtc ttttaaaatc agaggaggta gaagcttctg tcactagaaa atatgacaaa
    10141 tgtcataaaa aattctgttc aaaacaagca agatacacta tacaataaaa cacaatcaga
    10201 aaaatctaag gcaacttcct caaaagagat atcaaactca attcacacca caatgtaaac
    10261 taatacttat ttaaaatcaa aaagagtaga aatttttatc ag
//
LOCUS       DAVLTT010000066         9930 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLTT010000066 DAVLTT010000000
VERSION     DAVLTT010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9930
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.066"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            248..343
                     /locus_tag="VYN15_001788"
                     /pseudo
     CDS             248..343
                     /locus_tag="VYN15_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(596..1216)
                     /locus_tag="VYN15_001789"
     CDS             complement(596..1216)
                     /locus_tag="VYN15_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1453074.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1216..1698)
                     /locus_tag="VYN15_001790"
     CDS             complement(1216..1698)
                     /locus_tag="VYN15_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV1453075.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1698..2540)
                     /locus_tag="VYN15_001791"
     CDS             complement(1698..2540)
                     /locus_tag="VYN15_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV1453076.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2635..3435)
                     /locus_tag="VYN15_001792"
     CDS             complement(2635..3435)
                     /locus_tag="VYN15_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV1453077.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSAQEMEKPAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3579..4958
                     /gene="glmU"
                     /locus_tag="VYN15_001793"
     CDS             3579..4958
                     /gene="glmU"
                     /locus_tag="VYN15_001793"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV1453078.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAEQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGVVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4968..5513
                     /locus_tag="VYN15_001794"
     CDS             4968..5513
                     /locus_tag="VYN15_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1453079.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5525..5839
                     /locus_tag="VYN15_001795"
     CDS             5525..5839
                     /locus_tag="VYN15_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV1453080.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5856..6548
                     /locus_tag="VYN15_001796"
     CDS             5856..6548
                     /locus_tag="VYN15_001796"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV1453081.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6625..7116
                     /gene="rocS"
                     /locus_tag="VYN15_001797"
     CDS             6625..7116
                     /gene="rocS"
                     /locus_tag="VYN15_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV1453082.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7214..7804
                     /locus_tag="VYN15_001798"
     CDS             7214..7804
                     /locus_tag="VYN15_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV1453083.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7813..9576
                     /locus_tag="VYN15_001799"
     CDS             7813..9576
                     /locus_tag="VYN15_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV1453084.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            9790..>9930
                     /locus_tag="VYN15_001800"
     CDS             9790..>9930
                     /locus_tag="VYN15_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1453085.1"
                     /translation="MAYSIDFRKKVLSYCERIGSITEASHVFQISRNTIYGWLKLKEK
                     TGE"
BASE COUNT         3074 a         1716 c         2118 g         3022 t
ORIGIN      
        1 gtctaacttt tggggggcag ttcatttaac acctgataat atgcgttttt tgattttaaa
       61 gactttttga ccagtctcat ttttttaact tgatactcag tgcaaagcaa agattaaact
      121 aggaagctag ctgtaggctg ctcaaagaac agctttgagg ttgtagataa aacttgtgag
      181 gtaaccaaca tatataatgt gaagctgacg tggtttgaat agattttagg agggtatgag
      241 tctggaagtt ttaatggata atgcaagatt ccatagaatg ggtaagctag agttcttatg
      301 tgaagagttt gggcataaac ttttaccttt tcctccctac tcatcttagt atagaaaagt
      361 gaatctgaaa tagtacataa ctgcttctaa aacattctta taaattgatt taaattctca
      421 aatcatatta ttcagttctt atttcatttt gctctacaat cctgttgaga agacacgtgt
      481 tcatatcaaa aaggtattgg caagttgcaa taccttttta cgaggctctt ttatcttatt
      541 tttgtttcaa ctgactatat ctcctatggt tctagttcag aaggctaggc tataattatg
      601 attgataaga agtatcattc caagtattga gagtgaatgt ttcaaaatca tgggtttcta
      661 taatggtcag gctggcattt gctagaccgc catctttacg aagaagtggt tctttatagc
      721 ctaggagagt acgaagactg gcagtaagat tggcgccgtg tccgacaatt agaatacgct
      781 cagctggact atcttttaat gatttgataa attggatggt ccgctgagtt gtactataga
      841 gagattcggc tccgaacatt cgagtgtcaa attgagcaag atttgaacga aaagcctgga
      901 tttgttgcgg gtaaatagct tccaaggttg caattttcaa accttctaac ttcccaagtt
      961 gccattcacg gagattagga acgatttcta aagaacaggg ggtatggagt tgactttgga
     1021 taatctcagc agatttgacc gctcgaggta aatcacttga ataaatctga tcaaaaggaa
     1081 tttccttgag atactggcca agtcgtttta gggtttcaat ggattcagga agaagaggag
     1141 aatcaccgct agcaccttga aaacgacctt cttggttcca gagggtacga ccgtggcgga
     1201 caaagtagag tttcattact tgatgtcctc caaaatatct acaaagtctg cctttacaaa
     1261 gctagccaag tcttgtggcg cgacgataat gctgtgtccg acttcgcctg cagagacaat
     1321 catttgatcc aaatctagag caattttatc gataaaaatg ggataattgt gtttctgacg
     1381 aattccgaca ggattattgg ctccatgaat gtaaccagtt gttttttcta agtccttttg
     1441 tggaatcatg ctcacttttt tattgccaga aattttagct agtttctttt cagacaagtg
     1501 ctgagtgata gggacaattc cgataatcgg tcctgtcttg tctcccaaaa gcgccaaggt
     1561 tttgaaaatc tgatctcgtt cataaccttg aggaagctct ccttctaggg cattgatttg
     1621 aatcccctga tgagggatag ctgctttaga taggatttgt tccaccaatg tttttttgat
     1681 tttaactttt tttgccatta tttatattta tcctccaatt gactcatcca aataccaagc
     1741 cagattccca gcgcaaagaa gaaggcgatg atgacataac cgacaagtga aagtcctgtg
     1801 tattggatac tttcagcgtt tcctgcattt ggaattaaga tcaaaagggt acttgatagg
     1861 acgataccga tgatgaaatg atagacgcgt gagtggtagt tgtttaaggc ataatccatc
     1921 aattttgaaa aaacgatgag agttgcacct gcaccaattc caatcggaaa gaaggttccc
     1981 aagagatcaa aagttttaaa accagtcaac ataggagcat agagtcccaa aatcaaaagt
     2041 aaattcgatg ggctgaggcc aggaaccaag acgccaaggg ccaatagtgc gcctgctagg
     2101 acgaagttaa gaaagctggc gcttaaggtt ccaacgacaa aatttaaggc atagagtcct
     2161 aatccagaaa tgataaaggt tgtccataac caagctaaat caatcttgtc tcggtcagat
     2221 tctcgagttg attctttgag gaggctagga actgtaccga taatagctcc cgcaaagctc
     2281 cataatacaa agacctgata attttcaagc aggtattcaa tcgggtagga aaataagccg
     2341 attcccagaa gcataccgat ggcaactgga ataaagtaca aaacattttc tttaaggtct
     2401 ttaaagggat gggccagaaa gccaatcatt cgttcataga ttcctaagat tgctgctaga
     2461 acccctccgg aaattcccgg taggataaat ccaagagcaa ttacaatccc tttaataacg
     2521 cgtgctaacc atgagagcat atatttcctc caactatttc tatttcaaaa aatccttact
     2581 atattgtatc acaatcagac acaaaaagaa aaagcaaatg ataaacaaat gcttttaagg
     2641 ttttaaaaaa agttttcgaa aggtttcttc tttatttttt aagggagaga taacgttgat
     2701 atctaaatcg tggtcaaagc cggcaatttt tcctttagat gtgtattggt gaatatcata
     2761 atctaaatca gttttaggac tgctctccaa aaatcctgag tctgagccgt aggacggaat
     2821 ccaaacagag gtaaacttgc ctgtatcaat actgtgttct tccatgaagt agacaccaac
     2881 gtagatgccg atgtttttag cacctagtga tgctagtttt gctcgaaagt tttcgacacc
     2941 ttcgttcata ttagacatgg ttttgtcttc cacgtcaagc caatagtaac tagggctgta
     3001 aggagaggca gcattgtaga aaacttcggc aggcttttcc atttcttggg cactttttcc
     3061 agctacataa gcgtagacag caactgggac attccgcttt tgaagttcag tgatatgact
     3121 cttataggcc ttgtctattc cattgataaa tgaagcatca ttttcttttg tcgtttgagc
     3181 accactgtga acacgaacaa tagcacctga aatattttgt gagagggcat cgtagttgat
     3241 ttcctcagga cgctgccagc cagagaggtc aataatcggt ttgtctaagt gtttcaaagc
     3301 ctgtgcttca atctgtgcta tattggattt tgttttaaac gattggttgt cattaagtgg
     3361 gcgattgatg attaaaatga acatcataat ccccaaaaaa ctaaataaaa taagtggatg
     3421 aatttgtttt ctcatatctt ataattctac cctaaaaatc aaaaaaaatc aaaaaaatgg
     3481 gttaaggaag agactttaga gcattttttc attcaagagt gcggaatgat ttgaaatatg
     3541 gtataataaa agggaatttc tacagaaaag agaagattat gtcaaatttt gccattattt
     3601 tagcagcggg taaagggact cgcatgaaat ctgatttgcc aaaagttttg cacaaggttg
     3661 cgggtatttc tatgttggaa catgttttcc gtagtgtggg agctatccaa cctgaaaaga
     3721 cagtaacagt tgtaggacac aaggcagaat tggttgagga ggtcttggct gaacagacag
     3781 aatttgtgac tcaatctgaa cagttgggaa ctggtcatgc agtgatgatg acagagccta
     3841 tcttagaagg tttgtcagga cacaccttgg tcattgcagg agatactcct ttaatcactg
     3901 gtgaaagctt gaaaaacttg attgatttcc atatcaatca taaaaatgtg gccactatct
     3961 tgactgctga aacggataat ccttttggct atggacgaat tgttcgtaat gacaatgctg
     4021 aggttcttcg tattgttgag cagaaggatg ctacagattt tgaaaagcaa atcaaggaaa
     4081 tcaacactgg aacatacgtc tttgacaacg agcgtttgtt tgaggctttg aaaaatatca
     4141 ataccaataa cgctcaaggc gaatactata ttacagacgt cattggtatt ttccgtgaaa
     4201 ctggtgaaaa agttggcgct tatactttga aagattttga tgaaagtctt ggggtaaatg
     4261 accgtgtggc gcttgcgaca gctgagtcag ttatgcgtcg tcgcatcaat cataaacaca
     4321 tggtcaacgg tgttagcttt gtcaatccag aagcaactta tatcgatatt gatgttgaga
     4381 ttgctccgga agttcaaatc gaagccaatg ttaccttgaa agggcaaacg aaaattggtg
     4441 ctgagactgt tttgacaaac ggtacttatg tagtggatag cactatcgga gcaggagtgg
     4501 tcattaccaa ttctatgatt gaggaaagta gtgttgcaga cggtgtgaca gtcggtcctt
     4561 atgctcacat tcgtccaaat tcaagtctgg gtgcccaagt tcatattggt aactttgttg
     4621 aggtgaaagg atcttcaatc ggtgagaata ccaaggctgg tcatttgact tatatcggaa
     4681 actgtgaagt gggaagcaac gttaatttcg gtgctggaac tattacagtc aactatgacg
     4741 gcaaaaacaa atacaagaca gtcattggag acaatgtctt tgttggttca aattcaacca
     4801 ttattgcacc agtagaactt ggtgacaatt ccctcgttgg tgctggttca actattacta
     4861 aagacgtgcc agcagatgct attgctattg gtcgcggtcg tcagatcaat aaagacgaat
     4921 atgcaacacg tcttcctcat catcctaaga accagtagga gcctatcatg gagtttgaag
     4981 aaaaaacgct tagccgaaaa gaaatctatc aaggaccaat atttaaactg gtccaagatc
     5041 aggttgaatt accagaaggc aagggaactg cccgacggga tttgattttc cacaatgggg
     5101 ctgtctgtgt tttagcagta acggatgaac aaaaacttat cttggtcaag cagtaccgca
     5161 aagctatcga ggctgtctct tacgaaattc cagccggaaa attggaagta ggagaaaaca
     5221 cagcccctgt ggcagctgcc cttcgtgaat tagaggaaga aacagcctat acagggaaat
     5281 tagaactctt gtacgatttt tattcagcta ttggcttttg taatgagaag ttaaaactat
     5341 atttagcaag cgatttgaca aaagtggaaa atccgcgtcc gcaggatgag gatgaaacct
     5401 tggaagtcct tgaagtgagc ttagaagaag cgaaagaatt aatccaatca ggtcatatct
     5461 gtgatgccaa gacaattatg gctgttcagt attgggagtt gcagaaaaaa tagaggaggt
     5521 tagtatgggt aaatctttat taacggatga aatgattgaa agagctaata gaggcgaaaa
     5581 aatttcaggt cctcctttgc tagatgataa tgaggaaact aagattttac caacctcttc
     5641 ttcccgtttt ggttatgcca atcctaagga tcatggtttt agccaggaaa ccttgaagat
     5701 tcaggtcgaa ccatctattc ataaaagccg tcgtattgaa aataccaaga gaaatgtctt
     5761 caattctaag ttgaataaaa tcttatttgc ggtcatcttt ctcttgattt tgcttgtttt
     5821 agcaatgaaa cttttgtaat agaaaaggaa ttgaaatgaa aataggaatt attgctgcta
     5881 tgccagaaga actggcttat ctggtccagc atttagataa tacccaggag caagttgttt
     5941 tggggaatac ctatcataca ggaaccattg cttctcatga agtcgttctt gtagaaagtg
     6001 gaattggtaa ggtcatgtct gctatgagtg tggcgatttt ggctgatcat ttccaggtgg
     6061 atgcccttat taatacgggt tcagctgggg cagtagcaga aggtatcgct gttggggatg
     6121 tcgtgattgc tgacaaatta gcctatcatg acgtggatgt cacagctttt ggctatgctt
     6181 atggacaaat ggcgcaacaa ccgctttatt tcgaatcaga caaaaccttt gttgctcaaa
     6241 tccaagagag tttatctcaa ttggaccaaa actggcatct tggtttgatt gctacaggag
     6301 atagttttgt tgcaggaaat gacaagatag aagcgattaa gtctcatttc ccagaagttt
     6361 tagccgtgga gatggagggg gcagctattg ctcaagcagc gcatgccctc aatctcccag
     6421 tcttagtcat cagagctatg agtgacaatg ccaaccatga agcaaacatc ttttttgatg
     6481 agtttattat cgaagctgga cgtcgctctg cccaagtctt gttgaccttt ttgaaggctt
     6541 tagattaagc ggaaatttga cagtttttct agcttatgat aagatttaag taaagaaaag
     6601 ctagaaaacg tttcagagga tattatgagt attgaaatga ccgtcagtga gattgcagag
     6661 gtcttaggat tatctcgcca agcaatcaat aaccgtgtca aagaattacc agaagaagac
     6721 acagataaaa atgacaaagg ggtaacagtt gttaccagaa gtggcttgat taagctagaa
     6781 gaaatctata aaaaaacgat ttttgaagat gagcctgtca gtgaagatgt caaacaacgt
     6841 gaactgatgg agattctagt ggatgagaag aatgcagaaa ttcttcgtct ttatgaacaa
     6901 ttaaaagcca aggatcgtca gttatcagaa aaagacgagc agatgcgtat caaagaccgt
     6961 cagattgctg aaaaagacaa acaattagat cagcaacaac aattgaccct tcaagccatg
     7021 aaggatcaag aaaatcttaa gctagagctg gaccaagcaa aagaagaagt ccaatccact
     7081 aaaaaaggct tttttgctcg tttatttgga ggataatcaa ggagctgttt aggttaaatg
     7141 ctaacctgat ggcttctttt gtttgtgaat agtatagttg attagaacag agacagtaga
     7201 ggagaggtac agaatggaac gattagaaga ttacattgct tttgacttag aatttaatca
     7261 gcacgaagga caaacacact tgattcaagt atcggcagtg cgttttagag atggtcggga
     7321 aatcgatgcc tatgattcct atgttcatac cagcgtccct ctaaaaagct ttatcaatgg
     7381 tttgaccggg attacagctg agaccttaaa agatgctcct ccagttgaga aagtcttaga
     7441 agaattccaa gagtttgtgg gttctttgct gatgataggc tacaatgctg ctaaaagtga
     7501 tttacctatt ttagcagagc atggtttaga ctatagccaa cagtacaagg tggatttgta
     7561 tgatgaagct tttgaacgtc ggagttcaga tttacatggt attgccaatc tcaaattgca
     7621 aactgttgcc tcatttcttg gatttcaagg tcagtctcat aatagtttag aggatgctcg
     7681 gatgacggcg cgtgtttacg aatccttctt agagtcggat caagctaggg aattgttaga
     7741 gacagaaagt agcttatcaa acaatccttt tggtggcttg gacttgtctc aattatttga
     7801 ctaggagtgc ctatgaaacc tgaaaaacct aaaaaattgg gtcttaaaca gatttacctc
     7861 aatcttgata aaatcctctt tctatttttc ttgattttta tgatagtgga gtatttgtgg
     7921 gtaccattca attcatggtt ggctagcttc ttattagatc agacaggtta tctttttatt
     7981 tcctataaca atgtcttagc catccttact cattctccat tgattagtct agctttttta
     8041 gccttgattg taattaacct tctggttgct tattttcaaa taggactcct ctttattggt
     8101 gctcgtcatc tcctctataa tgaaaagcga aggctaattg agtatatccg caaggttttc
     8161 catgaaagtt ttggatttat gaaaaagcta acttgcgcta aagccttgtt tatctttttc
     8221 tatatagcta tgctgtttcc ttttatacgg aaaatgctga agatttatta tcttaataaa
     8281 atcgtcattc cagagtttat ccaagcttat ttagaagata gatattggat gtggtggctg
     8341 agcatcctac ttctatctct tatctttctc tatgtctctg tcagattgat gtttgccctt
     8401 ccgaagattg tatatgatca gctgactgtt cgagaagcag tgatgtttag cttggagaaa
     8461 accaagaaga gagttacttt ttatgcttgg aatttatttt acatcttgct caaagcacat
     8521 ttattatttt atcttccttt gatcccttta ttattggctc aaactttggt agatgatatc
     8581 actcagagag agtctctgat tcttggtatt ttgaattttg tcgtgattaa aaatctctat
     8641 tatatggctc tgacttattt tttggttaaa tttgtttcat ttttgacagg aaaggagctg
     8701 gatatgcttc ctaggagaga aaaagatcac atcgtgcgat ggggtgtcat gacttgtgcc
     8761 agtcttttct ttgccttaga aggttatatt tatctggagg ctcccatggt tcatctacct
     8821 caacttattt ctcaccgagg ggtttccaat gcaaatggga ttcaaaatac agtagagtcc
     8881 ttggaaacta cagcacaact caaaccagac ttggtggaga cggacgtgca ggaaacaaaa
     8941 gatgggcagt ttgtcatgat gcatgatgct aacttgaaaa atctagcagg tatcaataaa
     9001 agtcctcaag acttaaactt ggaggagctt aaagggattg atatttttga aaatggctac
     9061 cagactaaaa tttcaagctt tgaagattat ctcagtcgag ccaacgaact tggtcaaaaa
     9121 ttactaattg aaattaaaac cagtaaaaaa gatagtccag acatgatgaa ccgcttttta
     9181 gcccgttatg ctgcaaagct caagatttat ggacatcaaa tccagtcttt agactaccat
     9241 gttgtcgaaa aagtaagaca gtatgatgcc gaactgccag tttatttcat catgccctac
     9301 aattctgtct ttcctaaaac aagagcgaca ggatatacta tggagtactc aaccttggat
     9361 gaatattttg taagcaaact atggacaacg gatcagaaac tttatgtctg gactgtcaat
     9421 gattcagaag ctatcagcaa atctcttcac ttaggagtag atggagtgat tacagatgat
     9481 ttggaaaaag ttcagcggga aatagaagta gcccaagaag atccagaata tacggatttg
     9541 ctcttgaaaa aagcattgga attctttgaa ttttagtaat aaaaaagagg aacggttgtt
     9601 cctcccatga taggtaagta ttcttgtgaa tgcttgcttt tttgtggttg caatccgttt
     9661 acgagaattg tttgtattgt tcttgtttca atttacttta tagtgctttg aagttggaat
     9721 gctacactat aacttataaa atatagtaaa atgaaccaaa aatagtacac aatgtggtat
     9781 aatcttctta tggcatattc aatagatttt cgtaaaaaag ttctctctta ttgtgagcga
     9841 ataggtagta taacagaagc atcacacgtt ttccaaatct cacgtaatac catttatggc
     9901 tggttaaagc taaaagagaa aacaggagag
//
LOCUS       DAVLTT010000067         9704 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLTT010000067 DAVLTT010000000
VERSION     DAVLTT010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.067"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(415..1611)
                     /gene="tuf"
                     /locus_tag="VYN15_001801"
     CDS             complement(415..1611)
                     /gene="tuf"
                     /locus_tag="VYN15_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1453086.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2522..3391)
                     /locus_tag="VYN15_001802"
     CDS             complement(2522..3391)
                     /locus_tag="VYN15_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1453087.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3614..4135)
                     /locus_tag="VYN15_001803"
                     /pseudo
     CDS             complement(3614..4135)
                     /locus_tag="VYN15_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(4093..5199)
                     /locus_tag="VYN15_001804"
     CDS             complement(4093..5199)
                     /locus_tag="VYN15_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV1453088.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEVDTNSASLTGNIVSEGRTVTLVYRESEAPTTVTVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5310..5564)
                     /locus_tag="VYN15_001805"
     CDS             complement(5310..5564)
                     /locus_tag="VYN15_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453089.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5904..6350)
                     /locus_tag="VYN15_001806"
     CDS             complement(5904..6350)
                     /locus_tag="VYN15_001806"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1453090.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERTSIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDLLREVPTIFECLECFFKTR"
     gene            complement(6423..6748)
                     /locus_tag="VYN15_001807"
                     /pseudo
     CDS             complement(6423..6748)
                     /locus_tag="VYN15_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            6982..8700
                     /locus_tag="VYN15_001808"
     CDS             6982..8700
                     /locus_tag="VYN15_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV1453091.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            complement(8750..9704)
                     /locus_tag="VYN15_001809"
                     /pseudo
     CDS             complement(8750..9704)
                     /locus_tag="VYN15_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2782 a         1958 c         1851 g         3113 t
ORIGIN      
        1 tggtttggat ttcttcttta attgatttca tattactatt gtataatgct ttttgatttt
       61 agtctagtat tatactcttc gaaaatctct tcaaaccgcg tcagcttcgc cttgtcgtat
      121 agatgttact gacttcgtca gttctatcta caacctaaaa acagtgtttt gagcagtctg
      181 tagctaactt tctatagtaa aatgaaataa gaacaagaca aatcgatcag gacagtcaaa
      241 tcgatttcta acaatgtttt agaagtagat gtgtactatt ctagtttcaa tatattatag
      301 tttgctcttt gattttcatt gagtattagt tcaatatcta aaaaaagaac cttgccaagc
      361 aagattcttt tagtgtctga cttaaataat tgttcttctg ggaactaaat cgaattaagc
      421 ttcgatttct gtaaccatac ctgaaccaac agtacgtcca ccctcacgga tagagaatgt
      481 agtaccttgt tctacggcga ttgggtgaat caactcaacg tcgattgtca cgttatcacc
      541 aggcattacc atttcagtac ctgctggaag ttcgattgaa cctgtaacgt cagtagtacg
      601 gaagtagaat tgtggacggt agttgttgaa gaatggagtg tgacgtccac cttcttcttt
      661 agtaaggatg tagacttcac ctttgaattt agtgtgtggg ttgattgaac ctggtttagc
      721 gataacttgt ccacgttcga tttcatcacg ttgaacacca cgaagaagga cacctacgtt
      781 atctccagca agaccttcgt caagttgttt acggaacatt tcaacaccag taacaactgc
      841 tttttgagtt tcttctttga taccaacgat ttcgatttcg tcgttgactt taacgatacc
      901 acggtcgata cgtcctgaag caactgtacc acgtccagtg attgagaata cgtcctcgac
      961 tggaagaagc aatggtttgt cagtgtcacg ttctggttct gggatatact catcaactgt
     1021 gttcatcaat tccataacga tgtcttcgta tttagagtca ccttcaagag ctttaagtgc
     1081 tgaaccttgg ataactggaa gatcgtcacc tgggaagtcg tattctgaca ataggtcacg
     1141 gatttccatt tcaaccaatt caagcaattc ttcgtcgtca accaagtcaa ctttgttcat
     1201 gaagacgata aggtgtttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg
     1261 tggcattggt ccgtcagttg aagctactac aaggatagct ccgtccattt gagcagcacc
     1321 agtgatcatg tttttaacgt agtccgcgtg tcctggagcg tcgatgtgag cgtagtgacg
     1381 tttttcagtt tcgtactcaa cgtgcgcagt gttgatagtg ataccgcgtt cgcgttcttc
     1441 tggagcagca tcgatagacg catagtcttt aggttggtta actgatgaag gcaagcgacg
     1501 tgccaaaaca gttgtgatag ctgcagttag ggtagtttta ccgtggtcaa cgtgtccgat
     1561 agtaccaatg ttaacgtgtg gtttactacg atcgtatttt tcttttgcca tttgagtaaa
     1621 agcctccaat aaaatatatt ttatagatag acagtaggca atacagtcta actttcctta
     1681 ctattttatc aaatttcagc taaattgcaa gtgttttaca acgtttttgt gaattattct
     1741 tggtaaaaat ttaactaatt aatagaaagt actaaataga cttatccttc aaggagtttt
     1801 cagcattatc catccactca cttgctgaaa atgtaaacag tctctggttt atatagtaaa
     1861 atgaaacaag aatagagcaa atcgatcagg acagtcaaat cgatttctaa caatgtttta
     1921 gaagtagatg tgtactattc tagtttcaat ctactataca acctcaaaac tgtgttttga
     1981 acaacctgcg gctagcttct tagtttgccc tttgattttc attgagtata aaattgcaga
     2041 taaaacgata acaatcatag gactcagcag agtcaatgta ggtcgaagaa tagcccccct
     2101 aatcgcttat tttatagcaa aatgaaatag aaactgaaca ttttgttgag gaaggtaaat
     2161 caattcctca caatgtttga gaaagaaggg aggactattc caacttcaac ccactataaa
     2221 gcagacttac aagataggga acccatctcc gataatatat agtagaatga aaactgcaca
     2281 atttgattgg agaattcaaa ccaatttcta acaatgtttt agaaacaagg gtctattatt
     2341 tcaactgcaa cctactatag cccattgaag ctggaatagc ccactgagac ttctaaacca
     2401 ctgctggaga ggagtttgtt tagagtttct ttcatttccc taaaaaatca aaaagagaga
     2461 accagtctga tcctctctta cttatagatg gtgctcactc aaatgttaaa ggagctattt
     2521 cttagagata aaggaatttg aatacagcta ctgccgcaat tgctgctgcg ataggtgcta
     2581 ctactggtac ccaagaatac caccattttg aatcgccttt atgctcacca agaactgatt
     2641 ttggaaggaa agcatgaagg agacgtggtc ccaagtcacg ggctgggttc aaggcaggtc
     2701 ctgtaggtcc tccaagtgat gttaccaaag ccataacgag gaatccaagt gccaagtgag
     2761 ccacagaaag tcctgaagca gtgtgtggag ccacctgtgc tttaatagcc aagtcagaaa
     2821 aatcaactgt ttgtcctgct tctattgcct tttgtttcat gaattgaagc acttcagcac
     2881 caaagaagtt tttagtcaaa ccaagagctg caaagaacaa aacaaatgaa ccaacaaact
     2941 cattaatcaa accattgaca gttgctgcat agcgactttc ttttgtacca tggtcaatac
     3001 ttgaaatagt tgagaaagtt cccaagatgt tatttggttt ttcagttttc aagtagaatg
     3061 gacggtatgt tgccacaact aaggcttggc caaagatagc ccccaagact tgcgcgataa
     3121 tgtaaggtac cacttgtgcc caagggaaaa gaccgctaac tgcaagccct agagtgaaag
     3181 cagggttgat gtgattccca gatacgttac caaacatcaa ggctgggatc ataaccccca
     3241 taccataacc aacagcgatg acgatccagc cactttggtg acctttcgta cctttaagtt
     3301 caacgttggc aactgcacca ttcccaagaa tgatcaaaat ggcagttccc aaaaattcag
     3361 tggcatactt cagtgcccat gtgaaatcca tttgctagat tctccttaaa attttttaga
     3421 tattccttat tttatcaatt tttaccctat ttagcaactg atttctggaa atatttttaa
     3481 aaaaatagga ttcatagttt cccagttcaa cgtacttgta agcgttttta ttcttcacga
     3541 aagacctcat tctcaaaacc aggaaaaagc ccacatctgt gatcttttcc ttgttcctag
     3601 attctaaaat ctattatttt tcatcttctt ttttcttgaa gaatcctaat cctagaccag
     3661 ctaacaaggt catgatacca gcactagcca aggtagcatt agcttctgta cctgtgtttg
     3721 gcaattcctc tctcttacct gtctcataag tcggaacttc tgggtctgga ttcactggag
     3781 tttcagtttt tggagtacct ggttctggag ttggtttatc tggtgttgat aaacggtcat
     3841 accttaccgt tatttcttta tcactagagt ctgacgtaac ttcttgtgat taaactgttg
     3901 gaatatctgg agctttgtac ttgtcaatct taccagatat aacctcgtcc cagtttcctg
     3961 ttgtccattc accgtaggtt acaactcccg tgaccttgtt ctcagttttt gtacggctta
     4021 aggttacagg ttgaacaaca tcttctttta cattttggtt cgtaacttta tcaacgtaat
     4081 gaatgatacg cgttatagtc ttcgtctcag tagaggttgc tgttttggga accactgttt
     4141 cctcaacatt ctcacggtag taatagtcaa ctgttgcacc gtcttctggt acgcatttgc
     4201 aggagttgct accaaggtgt atgttgtttt ccttgtgata actcggtctt ctttgtcctc
     4261 agttgttgtt ttcccttcaa tagtttttga ttctgtggta tactcagaac ctatcgctaa
     4321 atcagctttt ataacagact ctgccaactt ctcttggcta ccttctttat agtaattggc
     4381 tgttactgta acagtggttg gcgcttcgct ttctctataa actaaggtca ctgttctacc
     4441 ttcgcttaca atattcccag ttaaacttgc agaatttgta tctacttctt taaaagtata
     4501 atattttccg tcagtagtag tcatgctact gagtttttta tctgtgacat tgtagctggt
     4561 accaatcagt tgttttttat tggtaatgta ggttccgtca ctttcttttt ctccaattcc
     4621 agtatcattt ttcaatgata gcaaacgccc ttgttcatca acatagcgaa ctttcacatt
     4681 ttctgagatt agttctgcca attctgaggt ttttttcttt ttcttgattt cttcggttat
     4741 tttccctttc tcttcttcgg gaatatttag ttttggaatg attttttcaa caacggttcg
     4801 tgatggttcc acagtatctt ggatgactga aaagtcagct agaattggga gattatactg
     4861 aacacggtga ctttgagtgt ttactcctac tctttcatta ttctctgaaa atacttgtac
     4921 ggtataagaa acaacatctt ttcctaatag aacatcccca gtagagaaat agccgccttt
     4981 tcctagtttg ctatctccag agcccacttc tttcctaatc ttatcagata gttttttacc
     5041 agtcagtaca ttcgttcgca caatcccttt gtctacccct acaaagtggg agaacttttt
     5101 aaactcttca gaaccagatc tagcccaacc attattaagg gcatttgctt ttgtatttgt
     5161 attctctctc aaaagtttgg cgattagaat tatattcatc ggcacttaga gttgctgcta
     5221 tatctgactc ttgaatacca acttccttac taccatttct agcggcagta tatgtgtatt
     5281 tatctgtttc tacttctagc tgattatcct taacatgata ggtaattttc tcctggtata
     5341 agagtcttca gtagtttata tgctctgtca tcatctttag ctttagaagc agctgagttt
     5401 agccaagttg gggtattagg agtatcttta tcagcctgtt tcaagacatt attcaagtca
     5461 tttgctagcc tattggttgt cctcactgtg aaagttttct tccagtctga accactttta
     5521 ttagacttag atatgctcat gaaatcctgg tcaacattca acacaatatc gccttgtttt
     5581 ttagcatctt ccgttgcttc tgcttcaaat tgatcatgga gtttttgttg ctctggtgta
     5641 tagttttttt atttacacga tttaatgtac tattttttat tttagtatta agaactccat
     5701 taatacgatt tttaaactct gcttcaaaaa atcccttaat ttgttggtgc gcaagttcaa
     5761 cattcaaacc ttttttatac aagtcttcat tctgaacgat ttcggctaca cggtgaatgg
     5821 tttgattgta taccgtcttc tcttaaccag cagtatcctt agttttaatg actactcgat
     5881 aggttccttt agaaccgtta tagtcatcta gttttaaaaa agcattccaa acattcaaaa
     5941 atagttggaa cttcccttaa taaatccgtc actttctttt tcaagatagc ccaagcttgc
     6001 tcaataggat tcaaatccgg tgaataaggt ggtagaggta agaaaaagtg tttatcttgg
     6061 atgcagagtt catccaaaat gttcttggga tgaaaaccag cattgcccat gacaataaca
     6121 tgaggtgtct tcaaagcagg taggagttgc gttttgaacc actccacaaa gaaatcgctt
     6181 gtcatgcttt tcttgtaaat catgggagct ataaactctc cgtctacttg tcctgcaaca
     6241 attgaagttc gctcaaaacg acgtccgcta atcttttcat agactttctc ccctctagga
     6301 gcccctgcat aaggacgata gagatagcgg tcgattcctg tttcatcaat ataaacaggt
     6361 gctaggtgct ttaaactatt aaaattctta agaaataagg ctacttttct gggtcttgtt
     6421 ccttaaagct cgtcatcttt ttttaaagtg accttaatct gctttaaagc tgcccatact
     6481 gaaggaacag cacaatcaaa atgtgccgca atttcccgta aaaaagcatc tggatgagcc
     6541 tctacaaagg ctttcaattc ctctaaagga atctttcggt ttttgacgac tcgctttttc
     6601 ctctctatgt gttcttgttc acgtctttct tttcccacgt gaagagagtt ctgacgccaa
     6661 caccaaaaaa cttggctgcc tcgacatggc tgtgcccctc tttgatgtaa tctaatgctc
     6721 gctgtttaaa atcagtacta tatgccatag ctttattata atatgcttgt ttaaaactaa
     6781 gtaactatat caatgttttg ttatgagaag acttactttt tttactgaaa ttgaattttt
     6841 cctagcctca acatcatata accccaaaat tcaatctgac ctggtttgca gagattttcg
     6901 aagcagataa ggttttacta aaactaaaaa aaatgatata atcaaactga ttaaatgttt
     6961 taaaaataaa ggagaatttg aatgtcttac caagaaaatt accagaaatg ggttgatttt
     7021 gtggagcttc ctgactacct tcgtcaagat ttggaaaata tggacgaaaa aactaaggaa
     7081 gatgccttct atacaaatct tgaatttggt actgcaggta tgcgtggctt ggttggtgct
     7141 ggtacaaacc gtatcaacat ctacgttgtt cgccaagcta ctgaaggatt ggctcgtttg
     7201 attgagtcaa aaggtggaaa cgagaaagaa cgcggtgtag caattgccta cgatagccgt
     7261 cacttctcac ctgagtttgc ctttgaatct gcggcagttc ttgctaaaca cggcatcaaa
     7321 tcttacgtat ttgaaagcct tcgtccaact ccagaactat catttgcagt tcgtcatctc
     7381 aactgtttcg caggtatcat ggtcacagcc agccacaacc ctgctccatt taacggttac
     7441 aaggtttacg gtgaagacgg tggacaaatg cctccacacg atgcggacgc tttgactact
     7501 tatatccgtg caatcgaaaa cccatttgca gttgaagttg ctgatgtgga aactgaaaaa
     7561 gcttctggct tgattgaagt tatcggcgaa gctgttgaca tagaatacct taaagaggtt
     7621 aaggacataa acatcaaccc agccttgatt gaagaatttg gtaaagacat gaagattgtc
     7681 tacacaccac ttcatggtac tggtgaaatg ttggctcgtc gtgctcttgc ccaagcagga
     7741 tttgactctg ttcaagttgt tgaagcgcaa gcaactgctg acccagactt ctcaactgta
     7801 acatctccaa acccagaaag ccaagcagcc tttgcccttg ctgaagaact tggtcgtcaa
     7861 gttggtgcag atgttcttgt cgcaactgac ccagacgctg accgtgttgg tgttgaagtt
     7921 cttcaaaaag atggtagcta cctcaacctt tcaggtaacc aaatcggtgc tatcatggct
     7981 aaatacatct tggaagctca caaaaacgct ggaactcttc ctgaaaatgc cgctctctgc
     8041 aaatctatcg tttcaactga cttggtaacg aagattgctg aaagctacgg cgcaactatg
     8101 ttcaacgtct tgacaggttt caaatttatc gctgaaaaaa tccaagaatt cgaagaaaaa
     8161 cacaaccaca cttacatgat gggatttgaa gaaagcttcg gttacttgat taaaccattt
     8221 gtacgtgata aagatgccat ccaagccgtt cttgtcgttg ctgaacttgc tgcctactac
     8281 cgttctcgtg gtttgacact tgctgacggt atcgaagaaa tctataaaga atatggctac
     8341 tacgcagaaa aaacaatctc tgttactctt tcaggtgtcg atggtgctga acaaatcaaa
     8401 gcgattatgg ctaaattccg caacaatgct ccaacagaat ggaacgcaac agctatcact
     8461 gtcgtagaag acttcaaggc acaaactgct actgttgctg acggtactgt tacaaacttg
     8521 acaactcctc caagtgatgt gttgaaatac acacttgctg acggttcatg gattgccgtt
     8581 cgcccttcag gtacagaacc aaaaatcaag ttctacattg cagttgtagg ggaaaccaac
     8641 gaagaatcac aagctaagat tgctaacatc gaagcagaaa tcaatgcatt tgtaaaataa
     8701 agacctataa aagatggctt tttgtcaact gtagtgggtt gaaaaaaagc taagctcgag
     8761 aaaggacaaa tttcgtcctt tcttttttga tattcagggc gataaaaatc cgttttttga
     8821 agttttcaaa gtttcgaaaa ccaaaggcat tgcgcttgat aagtttgatg agattattgg
     8881 tcgcttccaa tttggcgttt gaatagggta gttgaagggc gttgacgatt ttctctttgt
     8941 cctttagaaa ggtcttaaag acagtctgaa aaataggatg aacctgctta agattgtcct
     9001 caataagtcc gaaaaatttc tctggttcct tattctggaa gtgaaacagc aagagttgat
     9061 agagctgata gtgatgtttc aagtcttgtg aatagctcaa aagcttgtca agaatttctt
     9121 tatttgttaa gtgcatgcga aaagtagggc gataaaaacg tttatcgctc aatttacggc
     9181 tatcctgttg aatgagtttc cagtagcgct tgatagcctt gtattcatgg gattttcgat
     9241 gaaactgatt catgatttgg acacgcacac gactcatagc acggctaaga tgttgtacaa
     9301 tgtgaaagcg atcaagaacg attttagcat tcgggagtga aacagcctgg gagactgttt
     9361 cagcctgagc ctagaaattt gaaagcgaag ctgtttagcc aagtcatagt aaggactaaa
     9421 catatccata gtaataattt tgacgcgaca tcggacaact ctatcgtagc gaagaaagtg
     9481 atttcgaatg atagcttgtg ttcttccctc aagaacagtg atgatattga gattgttaaa
     9541 atcttgcgca ataaagctca tctccatctc ccgattgaaa cagtcactcc ccggactgtt
     9601 tcaacgtccc aagacataat cttaggcaga tttctaaaat tacactcaaa gtggaagtca
     9661 ttgagcttgc gaatgacagt tgaagttgaa atggccagct gatg
//
LOCUS       DAVLTT010000068         9542 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLTT010000068 DAVLTT010000000
VERSION     DAVLTT010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9542
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.068"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            106..5046
                     /locus_tag="VYN15_001810"
     CDS             106..5046
                     /locus_tag="VYN15_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV1453092.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     ASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPV
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDNWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFSDVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLHYQGH
                     EVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNELTEAHKALNGQEKFTEEKTELDRLTGEVQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNT
                     VLPKPTYQPTSDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            5136..6332
                     /locus_tag="VYN15_001811"
     CDS             5136..6332
                     /locus_tag="VYN15_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV1453093.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            6468..6995
                     /locus_tag="VYN15_001812"
     CDS             6468..6995
                     /locus_tag="VYN15_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1453094.1"
                     /translation="MSYFKKYKFDKSQFKFGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            7072..7428
                     /gene="glnR"
                     /locus_tag="VYN15_001813"
     CDS             7072..7428
                     /gene="glnR"
                     /locus_tag="VYN15_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV1453095.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            7465..8811
                     /gene="glnA"
                     /locus_tag="VYN15_001814"
     CDS             7465..8811
                     /gene="glnA"
                     /locus_tag="VYN15_001814"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV1453096.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(8940..9026)
                     /locus_tag="VYN15_001815"
     CDS             complement(8940..9026)
                     /locus_tag="VYN15_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV1453097.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNS"
BASE COUNT         3076 a         1739 c         2091 g         2636 t
ORIGIN      
        1 atgttttagg ataaaaatgt gattatcatg attctagagt taaaaaacta cagaatataa
       61 agcgctttct tgaaaacaac aaaatcaatc ttttaggagg agaaaatgaa gaatccattt
      121 tttgaaagac gttgtcgtta cagtattcgt aagttatcag taggagcctg ctcgctgatg
      181 attggtgctg ttttatttgc tggtccagcc ttggctgaag aaactgcagt tcctgaaaat
      241 agcggagcta atacagagct tgtttcagga gagagtgagc attcgaccaa tgaagctgat
      301 aagcagaatg aaggggaaca tactagagaa aacaagctag aaaaggcaga aggagtagcg
      361 acagcatctg aaactgcaga agcagctagc gcagctaaac cagaggaaaa agcaagtgag
      421 gtggttgcag aaacaccatc tgcagaagca aaacctaagt ctgacaagga aacagaagca
      481 aagcccgaag caactaacca aggggatgag tctaagccag cagccgaagc taataagact
      541 gaaaaagaag tccagccaga tgtccctaaa aatacagaaa aaacattaaa accaaaggaa
      601 atcaaattta attcttggga agaattgtta aaatgggaac caggtgctcg tgaagatgat
      661 gctattaacc gcggatctgt tgtcctcgct tcacgtcgga caggtcattt agtcaatgaa
      721 aaagctagca aggaagcaaa agttcaagcc ttatcaaaca ccaattctaa agcaaaagac
      781 catgcttctg ttggtggaga agagttcaag gcctatgctt ttgactattg gcaatatcta
      841 gattcaatgg tcttctggga aggtctcgta ccaactcctg acgttattga tgcaggtcac
      901 cgtaacgggg ttcctgtata cggtacactc ttcttcaact ggtctaatag tattgcagat
      961 caagaaagat ttgctgaagc tttgaagcaa gacgcagatg gtagcttccc aattgcccgt
     1021 aaattggtag acatggcaaa gtattatggc tatgatggct atttcatcaa ccaagaaaca
     1081 actggagatt tggttaaacc tcttggagaa aagatgcgcc agtttatgct ctatagcaag
     1141 gaatatgctg ccaaggtaaa ccatccaatc aagtattctt ggtatgatgc catgacctat
     1201 aactatggac gttaccatca agatggtttg ggagaataca actaccaatt catgcaacca
     1261 gaaggagata aggttccggt agataacttc tttgctaact ttaactggga taaggctaaa
     1321 aatgattaca ctattgcaac tgccaactgg attggtcgta atccttatga tgtatttgca
     1381 ggtttggaat tgcaacaggg tggttcctac aagacaaagg ttaagtggaa tgacatttta
     1441 gacgaaaatg ggaaattgcg cctttctctt ggtttatttg ccccagatac cattacaagt
     1501 ttaggaaaaa ctggtgaaga ttatcataaa aatgaagata tcttctttac aggttatcaa
     1561 ggagacccta ctggccaaaa accaggtgac aaagattggt atggtattgc taacctagtt
     1621 gcggaccgta cgccagcggt aggtaatact tttactactt cttttaatac aggtcatggt
     1681 aaaaaatggt tcgtagatgg taaggtttct aaggattctg agtggaatta tcgttcagta
     1741 tcaggtgttc ttccaacatg gcgctggtgg cagacttcaa caggggaaaa acttcgtgca
     1801 gaatatgatt ttacagatgc ctataatggc ggaaattccc ttaaattctc tggtgatgta
     1861 gccggtaaga cagatcagga tgtgagactt tattctacta agttagaagt aactgagaag
     1921 accaaacttc gtgttgccca caagggagga aaaggttcta aagtttatat ggcattctct
     1981 acaactccag actacaaatt cgatgatgca gatgcatgga aagagctaac cctttctgac
     2041 aactggacaa atgaagaatt tgatcttagc tcactagcgg gtaaaaccat ctatgcagtc
     2101 aaactatttt tcgagcatga aggtgctgta aaagattatc agttcaacct aggacaatta
     2161 actatctcgg acaatcacca agagccacaa tcgccgacaa gcttttctgt agtgaaacaa
     2221 tcgcttaaaa atgcccaaga agcggaagca gttgtgcaat ttaaaggcaa caaggatgca
     2281 gatttctatg aagtttatga aaaagatgga gacaactgga aattactaac tggctcatct
     2341 tctacaacta tttatctacc aaaagttagc cgctcagcaa gtgctcaggg tacaactcaa
     2401 gaactgaagg ttgtagcagt cggtaaaaat ggagttcgtt cagaagctgc aaccacaacc
     2461 tttgattggg gtatgactgt aaaagatacc agcctaccaa aaccactagc tgaaaatatc
     2521 gttccaggtg caacagttat tgatagtact ttccctaaga ctgaaggtgg agaaggtatt
     2581 gaaggtatgt tgaacggtac cattactagc ttgtcagata aatggtcttc agctcagttg
     2641 agtggtagtg tggatattcg tttgaccaag ccacgtaccg ttgttagatg ggtcatggat
     2701 catgcagggg ctggtggtga gtctgttaac gatggcttga tgaacaccaa agactttgac
     2761 ctttattata aagatgcaga tggtgagtgg aagctagcta aggaagtccg tggtaacaaa
     2821 gcacacgtga cagatatcac tcttgataaa ccaatcactg ctcaagactg gcgcttgaat
     2881 gttgtcactt ctgacaatgg aactccatgg aaggctattc gtatctataa ctggaaaatg
     2941 tatgaaaagc ttgatactga gagtgtcaat attccgatgg ccaaggctgc agcccgttct
     3001 ctaggcaata acaaggtaca agttggcttt tcagatgtac cggctggagc aactattact
     3061 gtttatgata atccaaattc tcaaactccg cttgcaacct tgaagagcga agttggagga
     3121 gacctagcaa gtgcaccatt ggatttgaca aatcaatctg gtcttcttta ttatcgtacc
     3181 cagttgccag gcaaggaaat tagtaatgtc ctagcagttt ccgttccaaa agatgacaga
     3241 agaatcaagt cagtcagcct agaaacagga cctaagaaaa caagctacgc cgaaggggag
     3301 gatttggacc ttagaggtgg tgttcttcga gttcagtatg aaggaggaac tgaggacgaa
     3361 ctcattcgcc taactcacgc aggtgtatca gtatcaggtt ttgatacgca tcataaggga
     3421 gaacagaatc ttactctcca atatttggga caaccggtaa atgctaattt gtcagtgact
     3481 gtcactggcc aagacgaagc aagtccgaaa actattttgg gaattgaagt aagtcaggaa
     3541 ccgaaaaaag attacctagt tggtgatagc ttagacttgt ctgaaggacg ctttgcagtg
     3601 gcttatagca atgacaccat ggaagaacat tcctttactg atgagggagt tgaaatttct
     3661 ggttacgatg ctcaaaagac tggtcgtcaa accttgacgc ttcattacca aggccatgaa
     3721 gttagctttg atgttttggt atctccaaaa gcagcattga acgatgagta cctcaaacaa
     3781 aaattagcag aagttgaagc tgctaagaac aaggtggtct ataactttgc ttcatcagaa
     3841 gtaaaagaag ccttcttgaa agcaattgaa gcggccgaac aagtgttgaa agaccatgaa
     3901 actagcaccc aagatcaagt caatgaccga cttaatgaat tgacagaagc tcataaagct
     3961 ctgaatggtc aagagaaatt tacggaagaa aagacagagc ttgatcgctt aacaggtgag
     4021 gttcaagaac tcttggctgc caaaccaaac catccttcag gttctgccct agctccgctt
     4081 cttgagaaaa acaaggcctt ggttgaaaaa gtagatttga gtccagaaga gcttacaaca
     4141 gcgaaacaga gtctaaaaga tctggttgct ttattgaaag aagacaagcc agcagtcttt
     4201 tctgatagta aaacaggtgt tgaagtacac ttctcaaata aagagaagac tgtcatcaag
     4261 ggtttgaaag tagagcgtgt tcaagcaagt gctgaagaga agaaatactt tgctggagaa
     4321 gatgctcatg tctttgaaat agaaggtttg gatgaaaaag gtcaagatgt tgatctctct
     4381 tatgcttcta ttgtgaaaat cccaattgaa aaagataaga aagttaagaa agtatttttc
     4441 ttacctgaag gcaaagaggc agtagaattg gcttttgaac aaacggatag tcatgttatc
     4501 tttacagcac ctcactttac tcattatgcc tttgtttatg aatctgctga aaaaccacaa
     4561 cctgctaaac cagcaccaca aaacacagtc cttccaaaac ctacttatca accgacttct
     4621 gatcaacaaa aggctcctaa attggaagtt caagaggaaa aggttgcctt tcatcgtcaa
     4681 gagcatgaaa atactgagat gctagttggg gaacaacgag tcatcataca gggacgagat
     4741 ggactgttaa gacatgtctt tgaagttgat gaaaacggtc agcgtcgtct tcgttcaaca
     4801 gaagtcatcc aagaagcgat tccagaaatt gttgaaattg gaacaaaagt aaaaacagta
     4861 ccagcagtag tagctacaca ggaaaaacca gctcaaaata cagcagttaa atcagaagaa
     4921 gcaagcaaac aattgccaaa tacaggaaca gctgatgcta atgaagccct aatagcaggc
     4981 ttagccagcc ttggtcttgc tagtttagcc ttgaccttga gacggaaaag agaagataaa
     5041 gattaaatat cgaaaaatct tgtgaaatct ttccttatat ttccaaagtg tgatataata
     5101 gtttcgaata aaataaataa aggagttttt gtaacatggc aaaacttact gttaaagacg
     5161 ttgacttgaa aggtaaaaaa gtcctcgttc gtgttgactt caacgtacca ttgaaagatg
     5221 gcgtaatcac taacgataac cgtatcacag cagctcttcc aactattaag tacatcatcg
     5281 aacaaggtgg acgtgcaatt cttttctctc accttggacg tgtgaaagaa gaagctgata
     5341 aagctggtaa atcacttgct cctgtagcag ctgacttggc agcaaaactt ggtcaagatg
     5401 ttgttttccc aggtgtcact cgtggtgctg aattggaagc ggcaatcaac gctcttgaag
     5461 atggacaagt tctcttggtt gaaaacactc gttacgaaga tgttgacggc aagaaagaat
     5521 ctaaaaacga tcctgaactt ggtaaatact gggcatcact tggagatggt atcttcgtaa
     5581 acgatgcatt cggtacagct caccgtgcac acgcatctaa tgttggtatc tcagcaaacg
     5641 ttgaaaaagc agttgctggc ttccttcttg aaaacgaaat tgcctacatc caagaagcag
     5701 ttgaaactcc agaacgtcca ttcgtggcta tccttggtgg ttcaaaagtt tcagacaaga
     5761 tcggtgttat cgaaaacttg cttgaaaaag ctgataaagt ccttatcggt ggtgggatga
     5821 cttacacatt ctacaaagca caaggtatcg aaatcggtaa ctcacttgta gaagaagaca
     5881 aattggatgt tgcgaaagct cttcttgaaa aagcaaatgg taaattgatc ttgccagttg
     5941 actcaaaaga agctaacgca tttgctggtt acactgaagt gcgtgacact gaaggtgaag
     6001 cagtttctga aggcttcctt ggtcttgaca tcggtccaaa atctatcgcc aaatttgacg
     6061 aagctttgac tggtgccaaa acagttgtat ggaacggacc tatgggtgta tttgaaaacc
     6121 cagatttcca agctggtaca atcggtgtga tggacgctat cgtgaaacaa ccaggagtta
     6181 aatcaatcat cggtggtggt gactcagctg ccgcagcgat taaccttggc cgtgcagaca
     6241 agttctcatg gattagtacg ggtggtggag catcaatgga acttcttgaa ggtaaggttc
     6301 ttccaggact tgcagccttg acagaaaaat aagattttat aaacaaatca aagaagagag
     6361 ggatgagagt tcctcttttc ttttgcttaa aataaaaacg cttcctctca actattactc
     6421 ataaaaatca ccgatttatg ataaaatgga aatagaaagt tgagattatg agttatttta
     6481 aaaaatataa attcgataaa tcccagttca aatttggtat gcgaaccttt aaaacaggta
     6541 ttgctgtttt tctagttctc ttgatttttg gcttttttgg ctggaaaggt cttcaaattg
     6601 gtgctttgac agccgttttt agccttaggg agagttttga tgagagtgtt cattttggga
     6661 cttcgcgtat tctaggaaat agtatcggtg gactctatgc cttggtcttc ttcttattaa
     6721 ataccttttt ccacgaagcc ttttgggtga ccttggtagt tgttccaatc tgcaccatgt
     6781 taaccattat gacaaatgta gccatgaata acaaagcagg ggttattggt ggtgtagcag
     6841 ctatgttaat cattacccta tcaattccaa gtggtgagac aatttcgtac gtgtttgtgc
     6901 gtgtatcaga aacgtttatg ggagtttttg tcgcaattat cgtaaattac gatattgatc
     6961 gtattcgtct ctttttagag aaaaaagaaa aataatgtta cattttataa cattatcaat
     7021 tgacgtttgt ctttttttag actataatag acagaaagaa ggaaattgta aatgaaggaa
     7081 aaagaatttc gccgaaatat ggctgttttt cctattggca gtgttatgaa gttgaccgat
     7141 ctatcggcgc gtcagattcg ttattatgaa gatcaagagt tgatcaagcc cgatcgaaac
     7201 gaaggaaatc gtcgcatgta ttccttgaat gacatggatc gtctgcttga aatcaaagat
     7261 tatatctctg aaggttataa tatagctgcc attaagaaaa aatatgctga acgtgaagcg
     7321 aaatccaaga aagcggttag tcagactgaa gtacgtcgtg cacttcacaa tgaactcctc
     7381 caacaggggc gttttgcttc agtacagtca ccttttggtc gcggttaggc aaccgcaagt
     7441 agtcatagat taaggagaaa acttatgcca atcacagctg cagatattcg tcgtgaagtc
     7501 aaggaaaaaa atgttacctt tattcgtctt atgttctcag atattttggg aaccatgaaa
     7561 aacgtcgaaa ttcctgctac agatgaacag ttagataagg tcttgtcgaa caaggttatg
     7621 tttgatggat cttctattga aggttttgta cgtatcaatg agtcggatat gtacttgtac
     7681 ccggacttgg atacatggac agtcttccct tggggagatg aaaatggaag tgttgcaggt
     7741 ctgatctgtg atgtctatac aacagaaggt gaaccatttg cgggtgaccc tcgtggtaat
     7801 ttgaaacgag ctcttcgtca catggaagaa gttggattca aatccttcaa ccttggtcca
     7861 gagccagaat tcttcctatt taagttggat gaaaatgggg acccaacact tgaagtgaat
     7921 gacaagggtg gctactttga tttggcacct actgaccttg cggacaacac acgtcgtgag
     7981 attgtgaatg tcttgaccaa aatgggattt gaagtagaag cgagtcacca cgaggttgcg
     8041 gttggacagc atgagattga ctttaagtac gatgaagttc tccgtgcttg tgataagatt
     8101 caaatcttta agcttgttgt taaaaccatt gctcgcaaac acggacttta cgcaacattt
     8161 atggcgaagc caaaatttgg tattgctgga tcaggtatgc actgtaatat gtccttgttt
     8221 gatgcagaag gaaataacgc cttctttgat ccaaatgatc caaaaggaat gcagttgtca
     8281 gaaacagctt accatttcct aggcggtttg atcaagcatg cttacaacta tactgccatc
     8341 atgaacccaa cagttaactc atacaaacgt ttggttccag gttatgaagc gcctgtttac
     8401 attgcttggg ctggtcgtaa ccgttcgcca cttgtgcgcg tacctgcttc acgtggtatg
     8461 ggaactcgtc ttgagttgcg ttcagtggat ccaatggcga acccttacat tgctatggct
     8521 gttcttttgg aagttggttt gtatggtatt gaaaataaaa tcgaagcacc agctcctatc
     8581 gaagaaaata tctacatcat gacagcagaa gagcgcaagg aagctggtat tacagacctt
     8641 ccatcaactc ttcacaacgc tttgaaagct ttgacagaag atgaagtggt taaagctgct
     8701 ctcggagatc acatctacac tagcttcctt gaagccaaac gaatcgaatg ggcaagttat
     8761 gcaaccttcg tttcacaatg ggaaattgat aattatttag acctttacta atactaatat
     8821 agaagaaaga ttgcctgtgg gtaaacagtc acacagcagt ctaagccatc aaatacctat
     8881 aacccttaaa atagcgattt cggtcgctat ttatttttcg aaaaatcctc ttgactcttt
     8941 tacgaattag atttatcatc agacgtgtag aagaaaatta aggagtcact atggaaaaat
     9001 tcaatttcaa aaacaatatc gggcaagaaa acaagttact tcaaatcgaa atctacaagt
     9061 ttactaactt ttgcaagctt caaaattaca catctgtaaa tattttttcg aaagatatat
     9121 ttgaagccat agtaaattga gactagaata gtacactaca tctgctaaaa atttctagaa
     9181 actaatttaa ctttcctaat cgatttgttt acatcttatt tcaatctact atattatctc
     9241 aataaatgat gatggcgact gttttgtttg tgcttgtcga tttttgaatc ctgatcgagc
     9301 ggaagaatat ttctgccgag gttgccaagg ggaaaatcct gaagatattg aattttatga
     9361 tgaacaatta caggcagaaa aggtggaggt tttgaatatt cgattggaag taaaaaattg
     9421 aattatctac aatctcatca acaataaacc tatttcaacc ccattatcta taggcgtatt
     9481 tttacgcctt tttatatact tgaagcacat aagaaacatt atgggaagtt tgctgatgga
     9541 ag
//
LOCUS       DAVLTT010000069         9076 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLTT010000069 DAVLTT010000000
VERSION     DAVLTT010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9076
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.069"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(306..1154)
                     /gene="dprA"
                     /locus_tag="VYN15_001816"
     CDS             complement(306..1154)
                     /gene="dprA"
                     /locus_tag="VYN15_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV1453098.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1250..1939)
                     /locus_tag="VYN15_001817"
     CDS             complement(1250..1939)
                     /locus_tag="VYN15_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV1453099.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1951..2829)
                     /locus_tag="VYN15_001818"
     CDS             complement(1951..2829)
                     /locus_tag="VYN15_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV1453100.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2819..3688)
                     /gene="licA"
                     /locus_tag="VYN15_001819"
     CDS             complement(2819..3688)
                     /gene="licA"
                     /locus_tag="VYN15_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV1453101.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGYYGVNRYQRA
                     VKGLASYGGTDEK"
     gene            complement(3705..4727)
                     /locus_tag="VYN15_001820"
     CDS             complement(3705..4727)
                     /locus_tag="VYN15_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1453102.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLL
                     LVGSSRSGRIDFENAIQMMKVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4732..5439)
                     /locus_tag="VYN15_001821"
     CDS             complement(4732..5439)
                     /locus_tag="VYN15_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV1453103.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVLHAEDLVDKYLPLHKERIIITKGGADRNTSIENIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIKLAQNHDAVDTVVEAVDTIVESTNGQFITGIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5794..7281
                     /gene="tacF"
                     /locus_tag="VYN15_001822"
     CDS             5794..7281
                     /gene="tacF"
                     /locus_tag="VYN15_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV1453104.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7291..8094
                     /locus_tag="VYN15_001823"
     CDS             7291..8094
                     /locus_tag="VYN15_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1453105.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8096..8905
                     /locus_tag="VYN15_001824"
     CDS             8096..8905
                     /locus_tag="VYN15_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1453106.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2852 a         1824 c         1520 g         2880 t
ORIGIN      
        1 tgttcacatc ttatttcaat tcactatact ttcccttata ctcaatgaaa atcaaagcgc
       61 aaaccaggaa gctagccaca ggttgctcaa aatactgttt tgaggttgca gatggaagct
      121 gacgtggttt gaagagattt tcgaagagta ttatatgaga aaaatcctct actctactaa
      181 tccacttaga aaaaacgcat attatcaagt gttaaaaact tgctaatatg cgttttatta
      241 tggaaatgtt gggttcattt tctcttaaaa ttgatttttt cttagaattc tagcttaggt
      301 catttttaaa attcaaattc cgcaagaaca tcttgcccac tggtgaccaa ttttgctcct
      361 tcttgaatca aatgatggca accgtctgat agtccatcta aaatgctacc aggaatagca
      421 aagacatcgc gtccttcttc cattgctcgc tcacacgtaa tgagactacc tgaacgcatc
      481 ttagcctctg ctacaatcac accacgacaa agtccagcaa tgatgcgatt acgggcagga
      541 aaatgaaatt tcagaggttg ttcgccaggt ccatattcac ttaaaaccaa atggtcattg
      601 ccgatgtagt cttgcaagcg tttattggct ttaggataaa acacatccag tcctgttcca
      661 atcactgcaa tggtttttcc gccattctga agagctgcca tatgagctgc tgtgtcaatg
      721 cccttggcca gaccactgac aataaccagt tcattttcca agccttgaat gactttttca
      781 actgatttag ctccctgttt gctacaagca cgactgccca cgaccgctac cttcgggaat
      841 ttcaggaggt caagatttcc cttgtaaaat aaaagtacag gcgcatcata tatttcactc
      901 aaatcccaag gataacagtc atctaaaata gagaaagatg gaaatttttg aaactctttc
      961 gacaaatgcg catcgtctat ctgaaaataa cgttccataa aaacggctgg attacggcaa
     1021 cctgatatat ctgcaatatc acccaacaaa agctcctgat caacattttc accgtattct
     1081 agcactttca aaatctgttg attggtcaaa cctgattttt ttaacttata gatttcatag
     1141 tttgtgattt tcataaataa ctccatttct ttttctactc atctatctat tcgtaaaagt
     1201 tcgtaaaaaa tcaaaaaaca tccgactatt ttgtcagatg ttggaatctt taattttcgt
     1261 ttttaagaat ttcttctaat ttacgatagt cttggacact atcgatctca taaatgctat
     1321 tgccttctaa ttcttcaaca tagacatcta gctctttgat attatcctta accatattgt
     1381 cccaatagag atcaacaaat tcaccacttg cataagcctt gtcgataaag ctgacaatct
     1441 tttctgcagt tggagcatcc cagaaggata caccactaag gatgcgacct gccttgctat
     1501 caacaataat gtcttgaacc ttgtagtcat ctccatagac caagaaccat tcgttggtac
     1561 aatcttcacg ataaacacta aaataagtcg aacgtgtcaa atcattgcgg aacatatttt
     1621 taaagagata attgtcagca tcaataacat agctgttggc caattcttct tttacaagat
     1681 agagagagta aaagttattg tagtcagcgt atttatcatt gaaaacgagg cgaacaccgt
     1741 atttttcttt taagtaatcg aattgttctt taagataacc aacaatgatg atgatgtcat
     1801 tgattccttt ttctttgaga aactcaattt ggtattcaat caaaggtttt tgattaacct
     1861 gaaccaaggc tttaggggta ttttcagtca taggacgcaa gcgagttccc aatcccgctg
     1921 ctaagataat ggctttcaca cgaatctcct ttattcttta ataataatat aaactccagc
     1981 aatgacgaca agtgacgtca taatggtcag catatctagc ggtgcaccca aaaaaacaac
     2041 tgcaaacaag accgtccata ctacatagct cacgttcaag cctgtagcct tggctggttg
     2101 caagcgattg atagcgatat aataagccaa gtaggaaatc atatcaaagg ctgcaaaaac
     2161 aatcatgaga cctagcaatt gtccattggc tactgcagta aatgactgat gagagaagag
     2221 cacaatcaca agataggaca agaacgaagt cacttgacgg attaagaggg cttcgatttc
     2281 actcagttca ctttccatag caaaggagct aagaacactc tcacttcccc atgcaatagc
     2341 acaaaccaaa gcacagagaa tcccaatgta gaaggaatta acctgttcaa ccttataggt
     2401 ctgggcaata atccctccaa taatcaagac aatcccaaat acagtatttt tcgaaatctt
     2461 gtgcttcaaa aagaagaaag ccaatagaac tgaaatcgca gggtaaatag ccgatacaga
     2521 tgaagctaaa gaacttccga tatacttaac tgcataaaga ttggcctgca taccgatagg
     2581 gcctgctagc aaggctccga tgataacact gacattgcga atatttaaga aaattgagag
     2641 gcgaactttc ccttctttta ccaagagaaa agctagtaag ataaagatgc tcaaaaaatc
     2701 atgagctgca gccaccacaa agggtgacaa atctgtaaaa atcgaaaaga tataagcact
     2761 aaccgttaga cccaagcccc agaaaatacc tgagagaagg ccaaaaggaa ctccgttttt
     2821 acttttcatc tgttcctcca taagaagcca aacctttaac agctctttgg taacgattca
     2881 caccatagta accaaaatct gcaccttgct cttccttata gacagtccat agactccaaa
     2941 tagtatcttg taaaatttta taaatagcaa tcttttcatg agaaaccggt gtttggtcac
     3001 tctcatagtg agataagaaa gtttcttcct cttgggaagt gaattcagac tctaaaaaga
     3061 gggcagccaa atcccacatt ggatcattca ttgatgaata ttcccagtca atcaaataaa
     3121 gtcgtccttg aggtgattcg ataaagtttt caggcaccaa atcgatatga caagattttc
     3181 tgtcaacacc taagtcagcc agtcttttct ctaaggagaa gactgcattt ctaacagatt
     3241 catagttggc ataaggaatt tgttcttcaa tcaaggattc gtattttttg atttcttcaa
     3301 aaggagcaaa ttctcctctt aattccttag cagatgtatg aatagtttgt aatattggag
     3361 caattttgtc gaacttggtc ttgattgacg ttgaatcaag cgtaatcgca gattcgatat
     3421 actcatttac tttgatgcca gcttcaatat caaaaagata attttttaca tctaagccta
     3481 aatcctttag tagttcaaga ttgtactttt catcttgtcg attgataagc ttttctgtcc
     3541 ctttaccaaa gaatttaaca atgtattgct tatttgttgt tttggccaaa tagttttgat
     3601 tggtcattcc acctagttgt tcaacactga ggacttcttc ttcttgacta agtaaggaag
     3661 aaattttttc tttaatgatt ttctccacaa ttaacctcca ggacttatac ttcccactta
     3721 aacactgttt taaaggctgt atttaaatcg gttgcaaaga cacggtgaat atctttaatt
     3781 tctcttacag gttcttctag ataaaggata tttttaagac gattggcaaa tttcttgact
     3841 ttcatcattt ggatagcatt ttcaaaatca atgcgaccag aacgagatga cccaaccaag
     3901 agcaagccct tttctaaggc atcgcgagta ttgagattga ctttatattc gctaactccc
     3961 atcatgagaa ttgttccctg aggacgaatg tagcgaatca agtcattaat agctggtcca
     4021 gtaccatcac caccacaaca ttcaaaagca tggtcaaagg ccaactcttc aggaatatta
     4081 tccgtaatat agcattcttt ggcaaatgag aagagttcca acttttccca atgacgacca
     4141 ataaccacaa tctctgcttc tggcaaagta taattgataa tattggcaac cacaaaagct
     4201 aaacttccat ctccaataac ggcgatccgc tcccgcttgc tatgagcaag agtcaataga
     4261 cgattcatag cgtgcatgcc cacactgaca aactctgtaa tagctgcaac cgtatcttca
     4321 atagcatcat aagccaccac acgatcttta gggagagaaa caaactctct cataaagcca
     4381 tcaaatccac tagacaagaa atgggtccct gtcatgtagt tttcatagaa ttcttcatca
     4441 ctctgcatag gagactgatt gggaatcatg acaacttttt gaccaacctc gtaggttcct
     4501 gtcgggtcag aaatgacggt tccacatgac tcgtgaatca ttgccattgg aagcttttta
     4561 ttcaaaatct tgggatcacg ttttccctgg tagtaacgct gatccgcatg acagacagcc
     4621 atgtagttgg gacggataag gatatgattc tcttggtcaa tagcctcttc ctgatatttg
     4681 acattgataa acttaggttt agttagttga taaatttgat taatcatttt actagtcttt
     4741 ctcaatcata ctttttgcaa tcttcaaatc tgttacggtt gtaatcttca gatttgagta
     4801 ttcgcctttg gccaaggcta catcttttcc tttgatcaca aagattttac atgcatctgt
     4861 caagatttcc ttctcttcat cagaaagaga tccataaagg tccatgaagt ccttgcaacg
     4921 gaatgtttga ggtgtttgtc cctgatagag gtgagcacga tttggaatac ctgtaatgaa
     4981 ttgaccattg gtactttcaa cgatagtatc cactgcttct actactgtat ccactgcgtc
     5041 atgattttga gcaagtttga tactgtcttg aatcatgcga agcgtaataa atggacgaac
     5101 agaatcgtgg gtaacaacga tatcctctgg agtaagcggg cgataagcat caatggcttc
     5161 aatgatgttc tcaatacttg tattgcggtc agcaccaccc tttgtaatga taatacgttc
     5221 cttatgaaga ggaagatatt tatctacaag atcttctgca tgtaaaaccc agtctccatg
     5281 aacaccaact acaatttttt caatacttgg ttccaagaca aatttttcaa ttgtatgaat
     5341 caaaataggt cgatcaccta gctctaaaaa ttgttttggc aagttactga ttcccatgcg
     5401 tgtgccagtt ccaccggcaa gaattcctgc ataaatcatc tattttctcc tttgtcttac
     5461 taaaaaactt attctctcta ttataccaca atctagtcct atataccaca atctagtcct
     5521 atcatgaaag aaatactggt cctccccttc tagaatagga gaattatgca gttctattat
     5581 tcaaagaaac aagcctattt ctagtaatga ctaggaattc tgtagcaatt actaataaat
     5641 gactgcgaaa ttttagagtc ctttagaata atatactttc cttaaagaaa acttaaaatt
     5701 taagatttga aacttcaaag tgattacttg acttactgcc cttcatttct tattagctaa
     5761 ctttatgata taatgaaaaa cgaggtaaat tgaatgaaaa gtataaaatt aaatgctcta
     5821 tcttacatgg gaattcgtgt cttgaatatt atttttccca tcctaactgg aacctatgtc
     5881 gcgcgtgtct tagaccgaac tgactatggt tacttcaact cagtcgacac tattttgtca
     5941 tttttcttgc cctttgcaac ttatggtgtc tataactacg gtttaagggc tatcagtaat
     6001 gtcaaggata acaaaaaaga tcttaacaga accttttcta gtctttttta tttgtgcatc
     6061 gcttgtacga ttttgaccac tgctgtctat atcctagcct atcctctctt ctttactgat
     6121 aatccaatcg tcaaaaaggt ctaccttgtt atggggattc aactcattgc ccagattttt
     6181 tcaatcgaat gggtcaatga agctctggaa aattacagtt ttctctttta caaaactgcc
     6241 ttcatccgta tcctgatgct ggtctctatt ttcttatttg ttaaaaatga acacgatatt
     6301 gttgtctata cacttgtgat gagtttatcg acgctgatta actacctgat tagttatttt
     6361 tggattaaaa gagacatcaa acttgttaaa attcacctaa gtgattttaa accactcttt
     6421 ctccctctga cagccatgtt agtctttgcc aatgccaata tgctcttcac ttttttagat
     6481 cgcctcttcc tcgttaaaac agggattgat gtcaacgtta gttactatac catagctcag
     6541 cgaattgtga ccgttatagc tggggttgta acaggtgcaa ttggagtgag tgtgcctcgt
     6601 ctcagttact atctggggaa aggagacaaa gaagcctatg tttctctggt taatagaggt
     6661 agtcgaatct ttaacttctt tatcattcca ctgagttttg gactcatggt tttaggacca
     6721 aatgccatcc tactttacgg tagtgaaaaa tatatcggag gcggcatctt gacctctctc
     6781 ttcgcttttc gtacgattat cctggcctta gataccattc ttggttccca aattctcttt
     6841 accaatggct atgaaaaacg tatcacagtc tatacagtct ttgctgggct actcaatttg
     6901 ggcttgaata gtctcctctt tttcaaccat atcgtggctc ctgaatacta cttactgaca
     6961 actatgttat cagagacttc tctacttgtt ttctatatca ttttcatcca tagaaaacaa
     7021 ctcatccact tgggacatat ctttagctat actgttcgat actctctctt ttcactttcc
     7081 tttgtagcaa tttatttcct gattaatttc gtgtatcctg tggatatggt cattaatttg
     7141 ccatttttga ttaatactgg tttgattgtc ttgctatcag ctatctctta tattagtcta
     7201 cttgtcttca caaaagatag cattttctat gaatttttaa accatgtcct agccttaaaa
     7261 aataaattta aaaaatcata ggagtttaaa atgaaacaac taaccgttga agatgccaaa
     7321 caaattgaat tagaaatttt ggattatatt gatactctct gtaaaaagca caatatcaac
     7381 tatattatta actacggtac tctgattggg gcggttcgac atgagggctt tatcccttgg
     7441 gacgacgata ttgatttatc catgcctaga gaagactacc aacgatttat taacattttt
     7501 caaaaggaaa aaagcaagta taagctccta tccttagaaa ctgataagaa ctactttaac
     7561 aactttatca agataaccga cagtacgact aaaattattg atactcgaaa tacaaaaacc
     7621 tatgagtctg gtatctttat cgatattttc cctatagatc gctttgatga tcctaaggtc
     7681 attgatactt gttataaact ggaaagcttc aaactgctgt ctttcagtaa acataaaaat
     7741 attgtctata aggatagcct tttaaaagat tggatacgaa cagccttttg gttgctcctt
     7801 cgaccagttt ctcctcgtta ttttgcaaat aaaatcgaga aagaaattca aaaatatagt
     7861 cgtgaaaatg ggcagtatat ggcttttatc ccttcaaaat ttaaggaaaa ggaagtcttc
     7921 ccaagtggta cctttgataa aacaatcgat ttaccctttg agaatttaag ccttcctgca
     7981 cctgaaaaat ttgatactat tttgacacaa ttttatggag attatatgac cctaccacca
     8041 gaagaaaaac gcttctacag tcatgaattt cacgcttata aattggagga ttaggatgca
     8101 atatttagaa aaaaaagaaa ttaaagaaat tcaactagcc ctgctggact atattgatga
     8161 gacttgtaag aaacatgata ttccttattt tctcagttat ggaaccatgc ttggagccat
     8221 ccgccacaaa ggtatgattc cttgggatga tgatattgat atttcccttt atcgtgagga
     8281 ttatgagcgt ttactgaaga ttattgaaga agaaaatcac cctcgctaca aggttctttc
     8341 ctacgataca tcttcttggt acttccataa tttcgcatcg attttggaca cttctactgt
     8401 tatagaagac catgttaagt acaaacgtca tgataccagc cttttcatcg atgtcttccc
     8461 aattgatcga tttacagact tgagcattgt cgacaagagc tataagtatg tggcccttcg
     8521 tcaactagct tatatcaaaa aatcacgagc agttcacggt gatagcaaac taaaagattt
     8581 tcttagatta tgtagctggt acgctctccg atttgtcaat cctcgctact tttacaagaa
     8641 aattgatcaa ctagtcaaaa atgctgtaac caacactcct caatatgaag gaggagttgg
     8701 gatcggtaag gaagggatga aagaaatctt cccagttgat acctttaaag aactgatttt
     8761 aactgagttt gagggccgta tgttgcctgt tcccaaaaaa tatgaccaat ttttaaccca
     8821 gatgtatggc gattatatga caccaccatc aaaagaaatg caagagtggt atagtcatag
     8881 cattaaagct tatcgcaaaa actgattgag gggtattata caaactacta agatagaggt
     8941 tattcaaaaa cataatttta gtagaaaatg aaatacatat tcccacaata aaacgcatca
     9001 tatcaaggtt tttgaaaaac cttgatatga tgcgttttat aattttaaag acttttttct
     9061 atagtagatt gaaata
//
LOCUS       DAVLTT010000070         8898 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLTT010000070 DAVLTT010000000
VERSION     DAVLTT010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8898
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.070"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            16..279
                     /locus_tag="VYN15_001825"
     CDS             16..279
                     /locus_tag="VYN15_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453107.1"
                     /translation="MVFAFHLPPDELITNVIFKEKINSMLKCYIDRLLYVFINPTHFT
                     EKVNLQFYGSFFSYEFICREVGNILKNKGVKCNLNFFEGEEYL"
     gene            387..1388
                     /locus_tag="VYN15_001826"
     CDS             387..1388
                     /locus_tag="VYN15_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1453108.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    1600..1829
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1996..2070
                     /locus_tag="VYN15_001827"
                     /pseudo
     CDS             1996..2070
                     /locus_tag="VYN15_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            2529..3890
                     /gene="trpE"
                     /locus_tag="VYN15_001828"
     CDS             2529..3890
                     /gene="trpE"
                     /locus_tag="VYN15_001828"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV1453109.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLHVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            3887..4453
                     /locus_tag="VYN15_001829"
     CDS             3887..4453
                     /locus_tag="VYN15_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV1453110.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            4464..5468
                     /gene="trpD"
                     /locus_tag="VYN15_001830"
     CDS             4464..5468
                     /gene="trpD"
                     /locus_tag="VYN15_001830"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV1453111.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            5465..6232
                     /gene="trpC"
                     /locus_tag="VYN15_001831"
     CDS             5465..6232
                     /gene="trpC"
                     /locus_tag="VYN15_001831"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV1453112.1"
                     /translation="MSQEFLARILEQKVREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            6219..6818
                     /locus_tag="VYN15_001832"
     CDS             6219..6818
                     /locus_tag="VYN15_001832"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV1453113.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEVAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVDLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLPQSFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            6796..8019
                     /gene="trpB"
                     /locus_tag="VYN15_001833"
     CDS             6796..8019
                     /gene="trpB"
                     /locus_tag="VYN15_001833"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV1453114.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            8012..8788
                     /locus_tag="VYN15_001834"
     CDS             8012..8788
                     /locus_tag="VYN15_001834"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV1453115.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(8760..>8898)
                     /locus_tag="VYN15_001835"
     CDS             complement(8760..>8898)
                     /locus_tag="VYN15_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV1453116.1"
                     /translation="RSVIFQIQFTIKLAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
BASE COUNT         2665 a         1628 c         2108 g         2497 t
ORIGIN      
        1 tatgatattt gtgaaatggt gtttgccttt catttacctc ctgatgagtt gataacaaat
       61 gttatcttta aagaaaaaat taactctatg ttaaaatgtt acattgacag gctattatat
      121 gtttttataa atcctacaca ttttactgaa aaagttaatc tacaatttta tggtagcttt
      181 ttctcatatg aatttatttg tcgtgaagtt ggaaacattc ttaaaaataa aggtgtgaaa
      241 tgcaatttaa acttttttga aggggaagaa tatttgtaaa attaattttg tgaatttgtg
      301 gatcttaaat aatttactaa attctcttgt taaaaaaaat taaatattgt atagtaatat
      361 tagaatgttc gtaatggagg actgaaatga aaaatataaa tgggaaaaag gtaactattt
      421 atgatattgc acgtttatca ggtttttctc caaaaacagt ttcacgagtt attaatggtg
      481 gagtaaatgt taaagaagaa acttatcaag cgattcaaaa agttatagag gaattgtcgt
      541 atattccaaa tgcgtatgca aaaaatttaa ctaaaaaaga agctataaat atattgattt
      601 ctgtaaaaaa aatcgactct tttcctttaa tttggtttca tacgctgtta gataaagtgt
      661 tacggacgtg taaagaattt ggtgttaatg ctatagttga gtactttgga gaggaggata
      721 caattagtaa ttcaattata tcaagcacag gtagcctagt agatggtgtt attgtttttt
      781 atgaaagtgt agatgatatc agaattcagt atttaaagaa gaaccatatg ccttttcttg
      841 ttttcggtga atctcaaacg tctggagtag tctatgtatc taataataat tttcaagcta
      901 cttatgatat gatgaaagct gtaactgaag aaaaatttaa aaatatgtgg ttgcttatgg
      961 ggggagaatc ccatgtgaat aaggatcgtg aaagaggtgt gcgttctttt ctgaatgata
     1021 aaaattactt tatggattta aaagtcattt atggcttatc tacaattgat tcagtttatt
     1081 cttatgcaat gcagcacttg actacccaaa attatccgga cattattttt gtttcaggag
     1141 atgaaaaggt tcagggcttg attcgtgcgt gctatgagaa aggaattctt attccagatg
     1201 atatttctat tattggattt gataatattc ctatttctca gtattatact ccagctttgt
     1261 ctacaattgc tcccaattat gttaaattgg ctaaagaaat gatagaaggt gttttagcaa
     1321 ttattaaagg ggaaagtgtc acatctgttg aagtttctcc taaatttgtt aggagacaga
     1381 gtttctagta ttgtttaatt cttgaaaatc ctagtggaaa agatggagtg ttctaaaata
     1441 agttctgttt agcctccatt cagtttctat tgagttggat ccaatttcta acaagtggga
     1501 catgttcatg ttcgatctaa ggaagacatg gtcacattcg aatgatattt tcaaaaaaat
     1561 cgtaaaaaag tcttgacaaa gaaaaaacaa agtattaaaa taagttcaac aaatcagaaa
     1621 agtaactatt tttgatcttc agggagcctg tggtggttgt gaataggtgg ttggaagtag
     1681 tgaaagtggg ctgattttga aaatgaattt gaaacaatga aaattcggtg cgcacacctt
     1741 acagtgcagc ttgttgttaa acaaggcaga gatgtaaagg gatagtccct ttataattga
     1801 ggtggcaccg cgttaccaac gccctcacac ggaagtatat tctgtgtgtg ggcttttttc
     1861 tatccgtcgt ttggtttatc ttttattagg gccttaagtc gctttgatga acttgagttc
     1921 tatctacagc tccttgccta ctactaaaag caaacaaaaa ggctggacta atacgaaaaa
     1981 agctagtaat actcaatgaa aatcaaagag caaactagga aactagccgc aggctgctca
     2041 aaacactgtt ttgaggttgc agatagaact gacgaagtca gtaaccatac ctacgataag
     2101 gcgacgttga cgcggtttga agagattttc gaagagtata aaggtgtacc gagatgaaca
     2161 tctcttcatc aatgtctctg gtcgtggagg caaggaccta gctgcgattg cagactacta
     2221 gaagctaaaa aataatagat ggaaaaatta cagttctttc tctcacagag agcttgtggt
     2281 tgctgaaaac aagcagagaa agctgtaaag ttgggttcat ctgaaacgag agaagaaaac
     2341 atcattctca agggagtgcc ctttatcgca cagcctgtta caggagatat ctgagacagg
     2401 aatgagagat aggagaaatc ctataattga ggtggcaccg cgaatttcgt cctcacgcaa
     2461 gttattttgc gtggggattt ttcatacagt caccacggac tagaagtaga actgaaaggg
     2521 aaattacaat ggaacgaatc attcatggag atgtcttatc accaatcttg gcttatatgc
     2581 gcttaaaggg gcaacataag gttattttag agagtattcc gagagacaag gaaacagctc
     2641 gtttttctat cctagcctat aatccagttt ttgagattaa gtttgaaaat ggggttctct
     2701 atcaaaatgg tcaagtgatt gatcgggatc ccttggattt cctttatgaa gtgattcata
     2761 agagtcagca ccactcagag ctaccttttg gtggtggagc cattggtttt gtgggttacg
     2821 atatgatttc gctttatgaa gaaattggtc aaatccctga ggatacaatt gggacgccag
     2881 acatgcattt ctttgtctat gagagctata tggtctttga ccacaagaag gagaagatac
     2941 atgtcataga ggatgcactt tatagtgagc gcagtcaaga ggccttggaa aaatccttga
     3001 accaagtgct tgaggaatta cgcattcctg ctccaaatga atttgaagat ttggatctat
     3061 ctccgttaga cttcaaaccg catatcgctc cacataagtt tgagggaatg gtagaaacag
     3121 ctcgtgactt gattcgtaac ggagatatgt tccaatgtgt actcagccag cgtttctcag
     3181 cagaagttac tggaaatcca tttgacttct acagaaatct ccacgtaact aatccttcta
     3241 attaccttta tttctatgat tttggggatt atcaaatcat cggagctagt ccagaaagtt
     3301 tggtttctgt caaaaatggc atcgtgacaa ccaatccgat tgcagggacg cgaccaagag
     3361 gggctacgga tgaagaagac aaggccttgg cgactgacct cctctctgat gagaaggaaa
     3421 cagcagaaca tcgaatgttg gtagacttgg ggcgtaacga tattggccgc atctctgaaa
     3481 cgaccagtgt ccaagtcact aagtatatgg aagtggagct cttccgttat gttatgcatc
     3541 tgaccagcgt ggtcaagggg cgtttgcttc cagaactcac tgccatggat gccttgaaag
     3601 ctacacttcc tgctggaacc gtttctggag cgccaaagat tcgagcgatg agacgcatct
     3661 atgaactgga aacggaaaaa cggggcgtat atgcaggagc aatcggctac ttgtctgcga
     3721 cgggtgatat ggatttggcc attgccatcc gaaccatgat tctcaaaaat caaagagcct
     3781 atgtgcaggc tggggcaggg attgtctacg actctatcgc ccaaaacgaa taccaagaaa
     3841 ccattaacaa agcaaaatct atgactagaa ttggagaact aagaccatga ttttattgat
     3901 tgacaactat gattctttta cctataactt ggcccaatac attgggaatt ttgcagaagt
     3961 tcaggttctg agaaatgatg attccaagct gtatgaagaa gctgagaaag cagatggtct
     4021 ggtcttttct cctggtcctg gttggccagt tgatgctgga aagatggaag acatgattcg
     4081 tgattttgca ggcaagaagc cgattcttgg gatttgtttg ggccaccaag ccattgcaga
     4141 agtctttggt ggtaagctag gtttggctcc aaaagtcatg catgggaaac agagcaatat
     4201 caactttgaa gcgccatctg ttttgtatca aggtattgag gaaggacgtg cggtcatgcg
     4261 ttatcacagt attttgattg aggaaatgcc agaagacttt gaagtgacag ctcgttcgac
     4321 tgatgaccaa gccatcatgg ggattcaaca taaaaaccta ccgatttatg gcttccagta
     4381 ccatccagag agcattggaa cgccagacgg cttgtcttct attcggaatt ttatcgagaa
     4441 ggttgtaaag tgaggaaact aggatgaaag agattattga aaaactagca aaatttgaaa
     4501 atttatcagg tgtggaaatg acggatgtca ttgagcgtat cgtaactggg cgtgtaactg
     4561 aagcgcagat tgcttctctc ctcttagctc ttaagatgaa gggggaaaca cctgaagaac
     4621 gcacagccat tgcccaagtc atgagaggac atgcccagca tattccaact gagattcatg
     4681 atgccatgga caactgtggt acaggtgggg acaagtcttt cagttttaat atttccacaa
     4741 ctgcagcctt tgtcttggct ggtggcggta ttcacatggc caagcatggt aaccgctcga
     4801 tttcttctaa atctggttcc gcagatgtcc tcgaagcctt gggaatcaat cttgacctca
     4861 aaccagctga actaggtaag gtctttgata aaactggaat cgtctttctc ttcgctaaaa
     4921 atatgcaccc agctatgaaa tacatcatgc cagctcgttt ggaattggga attccaacga
     4981 ttatgaactt gactggtcca ctgattcatc caatggcttt agaaacacag cttcttggaa
     5041 ttagtcgtcc agaactccta gaaagtacag ctcaggtttt gaaaaatatg ggtcgcaaac
     5101 gtgccatcgt ggttgctgga ccagaagggt tggatgaagc tggcttgaac ggaacaacca
     5161 agattgcact tcttgaaaat ggcgaaatca gcttgtcaag ctttactcca gaggatttgg
     5221 gaatggaagg ctatgctatg gaagatattc gtggtgggaa tgctcaggaa aatgcagaaa
     5281 ttttgcttag cgttctgaaa aacgaagcaa gtccattctt ggaaacgaca gtcttgaatg
     5341 ctggtcttgg tttctatgct aatggtaaga ttgatagcat caaggaagga gttgccttgg
     5401 cccgtcaagt gattgctaga ggcaaggccc ttgaaaaact cagactgtta caggagtacc
     5461 aaaaatgagt caggaatttt tagcacgaat cttagagcag aaggtgcgtg aggtggagca
     5521 gatgaagctg gagcaaatcc agcctctgcg ccagacctat cgcttggcag aatttttgaa
     5581 gaatcatcag gaccgcttgc aggtaatcgc tgaggtcaag aaagctagcc ctagtttggg
     5641 agatatcaat ctcgatgtgg atattgtgca acaggcccag acttatgaag aaaacggagc
     5701 agtgatgatt tcggtgttga cagatgaggt tttctttaaa gggcatttgg attatctacg
     5761 ggaaatttcc agtcaggtag agattccgac gctcaacaaa gactttatca tcgatgaaaa
     5821 gcaaatcatc cgcgctcgca atgcaggtgc gacagttatc ttgctcattg tggcagcctt
     5881 gtccgaagaa cgcctcaagg aactgtatga ctacgcgaca gagcttggtc tggaagtctt
     5941 agtggagact cacaatctag ctgaactaga ggtagcccac agacttggtg ctgagattat
     6001 cggggtcaac aaccgcaact tgactacctt tgaggtcgac ttgcagacca gtgtagattt
     6061 agccccttac tttgaggaag gtcgctatta catttctgaa tctgccattt tcacagggca
     6121 ggatgcggaa cgactagccc catactttaa cggaattttg gtagggacag ctcttatgca
     6181 ggcagaaaat gtggcccaga gaatcaagga gttgcagatt gacaaaggtt aaaatttgtg
     6241 gactatcgac caaagaagcg gtggaaacag ccgtttcagc aggagccgac tatatcggtt
     6301 ttgtctttgc acctagtaaa agacaggtga ctttagaaga ggtagctgag ttggcaaagc
     6361 ttattcctgc agatgtgaaa aaggttggag tatttgtttc accaagtcgg gtagaactgc
     6421 tggaagcgat tgacaaagtt gacttggact tggttcaagt tcacggtcag gtggcagatg
     6481 atttatttga gaatttgcct tgtgccagta ttcaggctgt gcaggtagat ggaaatgggc
     6541 atgtccccaa ttctcaggca gattatctac tctttgatgc ccctgtggca ggaagtggcc
     6601 agtcctttga ttggggtcaa ctggatacga ctggattacc tcagtctttc tttatcgcag
     6661 gtgggcttaa tgaagacaat gtagtaaaag caattcaaca ctttactccc tatgcagtag
     6721 atgtatcaag cggagtggag acagatggac aaaaagatca tgaaaagatt agaagattta
     6781 tagagagggt aaagaatggc atatcaagaa ccaaataaag atggatttta cggaaaattc
     6841 ggcggacgtt ttgtcccaga aacattgatg acagcagttt tggagttgga gaaggcctac
     6901 cgtgaaagtc aggcagaccc aagtttccaa gaggaattaa accaactttt gcgccagtat
     6961 gtgggacgtg aaactcccct ttactacgca aaaaatttga cccagcatat cggcggagcc
     7021 aagatttatc tcaaacggga agaccttaac catacaggag cccacaagat taacaatgcc
     7081 ttaggacaag tttggcttgc caaacgcatg ggtaaaaaga aaattatcgc agaaacgggt
     7141 gctggtcagc acggtgtggc aactgcaact gctgcagccc tctttaatat ggaatgtacc
     7201 atctacatgg gtgaggaaga tgtcaaacgc caagctctca atgtcttccg tatggagctt
     7261 ttgggagcta aggtcgaggc cgtgacagat ggttcgcgcg tgctcaagga tgcggtcaat
     7321 gcagcccttc gttcatgggt agctaatatc gatgataccc actatatcct tggttctgcc
     7381 ttggggcctc atccatttcc agaaatcgtt cgtgacttcc aaagtgtcat cggtcgagag
     7441 gctaaacaac agtaccgtga cttgacaggt cgagatctgc cagatgccct agtagcctgt
     7501 gttggtggtg ggtcgaatgc tatcgggctc ttccatccct ttgtagaaga tgagtcagta
     7561 gctatgtatg gaactgaagc agcagggctt ggtgtggata cagagcacca cgctgctacc
     7621 ttgaccaagg gtcgtccggg agttcttcac ggttctctca tggatgtgct ccaagatgcc
     7681 catggtcaaa ttcttgaagc cttctctatc tcagcaggtt tggactatcc tggtattggt
     7741 ccagaacatt ctcactacca cgatatcaaa cgtgccagct atgtccctgt gacagacgaa
     7801 gaagccttgg aaggattcca actcttgtct cgtgtggaag ggattatccc agccttggaa
     7861 tctagccatg ctatcgcttt tgcggtgaaa ttggccaaag aacttggacc agaaaagtct
     7921 atgattgtct gcctatcagg tcgtggggac aaggatgtgg ttcaagtcaa agaccgcttg
     7981 gaagcagatg cagcaaagaa gggagaagct catgcctaag acactaacag aaaaattaaa
     8041 tgctataaaa gcagctggaa aaggaatttt tgttccctat atcatggctg gagaccacga
     8101 gaaaggtttg gatggactag gagaaacaat ccactttcta gaagatttgg gtgtctctgc
     8161 aattgaagtg ggtattccct tttcagaccc tgttgcagat ggacctgtta tcgaagaagc
     8221 tggcttgcgc agtttagccc acgggacctc tacccaggct ttagttgaaa ccttgaaaac
     8281 cattgaaaca gagattccac tggtcatcat gacctacttc aaccccctct ttcagtacgg
     8341 tgtggagaac tttgtcaaag atctggctga tacagctgtg aagggcttga ttatcccaga
     8401 cttgcctcat gaacatgcca actttgtaga accatttttg gcagatacag atatcgcctt
     8461 gattccttta gtaagcttga ccacaggaat tgagcgccag aaagagttga ttgaaggggc
     8521 ggagggattc atctatgccg ttgccatcaa tggagtgaca gggaaatcag gcaattaccg
     8581 tgcagatttg gacaagcact tggcgcaact tcatcaagtg gccgacatcc cagtcttgac
     8641 aggttttggt gtatctagtc aagccgatct ggaacgcttc aatgcggtgt cagatggtgt
     8701 tatcgtcggt tcgaaaatag taaaagctct ccaccaagga gagccgattc aggactttat
     8761 caaacaagca gtagcttacc aaaaataatc aaacaagtag caagtaagag gaaaggcacg
     8821 aaaggaagtc tttccttttt cttttgcagg agaaaggcta gttttatagt gaattgaatc
     8881 tggaatatta cactacgg
//
LOCUS       DAVLTT010000071         8587 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLTT010000071 DAVLTT010000000
VERSION     DAVLTT010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.071"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..429
                     /locus_tag="VYN15_001836"
     CDS             <1..429
                     /locus_tag="VYN15_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000150981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV1453117.1"
                     /translation="YRYINKKYLDLPETFENYNVFVPEANGSGALGEVLSTPLIGEPL
                     IGHTDTFLSIGNFKTKFEADACIKFIKTKFARVLLGVLKVTQHNSRKTWYYVPLQDFT
                     VNSDIDWTQSVTDIDRQLDQKYDLSPEEIAFIENHVREMD"
     gene            594..3848
                     /locus_tag="VYN15_001837"
     CDS             594..3848
                     /locus_tag="VYN15_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001143847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1453118.1"
                     /translation="MPVEIKTTKEIHPKIYAYTTPTVTSNEGWIKIGYTERDVTQRIK
                     EQTHTAHIATDVLWTGDAAYTEEPDKGKTFKDHDFHHFLSFHDVERRPKTEWFYFNGT
                     PEKSKNLFDKFVQHDLSGYQPGKGQDYTLRQEQEEAVAKTLAYFQEHAGGKFLWNAKP
                     RFGKTLSTYDLARRMEAVNVLIVTNRPAIANSWYDDFETFIAGQTTYKFVSESDSLKS
                     RPILSRQEFLGILADDVRQLAFISLQDLKGSVYLGGEHDKLKWVTDLHWDLLVIDEAH
                     EGVDTFKTDQAFNKIRRNFTLHLSGTSFKALAKGDFTEEQIYNWSYADEQAAKYSWSL
                     EQEEENPYESLPQLNLFTYQMSQMIGEKLEKGAQIDGENIDYVFDLSEFFATDDKGKF
                     IHEHDVRNWLDTLSSNEKYPFSTKELRNELKHTFWLLERVASAKALKALLEEHPIYEN
                     YEIVLAAGDGRMSEEDDKVKLKSLDLVRKAIAENDKTITLSVGQLTTGVTIPEWTGVL
                     MLSNLKSPALYMQAAFRAQNPYSWSDNKGNHFRKERAYVFDFAPERTLILFDEFANNL
                     SLVTAAGRGTSATREENIRELLNFFPIIAEDRAGKMVEIDAKAVLTTPRQIKAREVLK
                     RGFMSNLLFDNISGIFQASQTVLDILNELPVEKEGKVQDSSDLLDFSDVTVDDEGNAV
                     VDHEIVVNQQMRLFGEKVYGLGESVAELVTKDEERTQKQLVNDLSKTVSSVIVEELKA
                     DYSLKTRETEQIKKQITATLENEIRKNDIERKISEAHIKQELQQQLKEANDKAQKDKI
                     QEDLEKRLEENKLIHKEKLEQTLKKEVEKMPEKFIEQVEIKRVEQLKQSAQDEIRDHL
                     RGFARTIPSFIMAYGDQTLTLDNFDAFVPEHVFYEVTGITIDQFRYLRDGGQDFAGHL
                     FDKATFDEAIQEFLRKKKELADYFKDQKEDIFDYIPPQKTNQIFTPKRVVKRMVDDLE
                     KENPGIFDDPSKTFIDLYMKSGLYIAELVKRLYNSNGLKEAFPNPEERLKHILEKQVY
                     GFAPSEIIYNISTNFIFGNLSKDISRKNFVLADTIPAAKEGSIQKLVDSYFENN"
     gene            complement(4147..5133)
                     /locus_tag="VYN15_001838"
     CDS             complement(4147..5133)
                     /locus_tag="VYN15_001838"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV1453119.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            5327..7795
                     /gene="gyrA"
                     /locus_tag="VYN15_001839"
     CDS             5327..7795
                     /gene="gyrA"
                     /locus_tag="VYN15_001839"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV1453120.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDVVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYEDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            7795..8538
                     /gene="srtA"
                     /locus_tag="VYN15_001840"
     CDS             7795..8538
                     /gene="srtA"
                     /locus_tag="VYN15_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV1453121.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         2765 a         1477 c         1838 g         2507 t
ORIGIN      
        1 tatcgatata ttaataaaaa atatttagat ttaccggaaa cattcgaaaa ttataatgtt
       61 tttgtaccag aagctaatgg aagtggtgcc ttaggtgaag tcttatcaac acccctaatc
      121 ggggaacccc taatcgggca tacagatact tttttatcta ttggtaattt taaaacaaaa
      181 tttgaagccg atgcttgtat taaatttatt aaaactaaat tcgctagagt attattaggt
      241 gttttgaaag ttactcagca taattcacgc aaaacttggt attacgtccc cctccaagac
      301 tttacggtca attcggacat tgattggaca caatcagtga ctgatattga ccgccagctt
      361 gatcaaaaat atgacctttc ccctgaagaa attgccttta ttgagaatca tgtaagggag
      421 atggattaga aaagtatttt tatttgacaa atagtgctca atgatctaaa atgactatat
      481 aggattaggt caggaagcat acgatgccct gacccttttt gtacttatga gatgagaaag
      541 tcatttgtta gataaattga cttcgttagc aaacgttcaa aaaaggaaaa cttatgccag
      601 tagaaattaa aaccactaaa gaaattcatc ctaaaatcta tgcctacacc acaccgacag
      661 taaccagtaa tgaaggctgg attaagattg ggtatacaga acgtgatgtc acacaacgta
      721 tcaaggagca aacgcataca gctcatatag ctacagatgt cttatggact ggtgatgcag
      781 cttatacaga agagcctgat aaggggaaaa ctttcaagga ccatgatttc caccatttcc
      841 tttctttcca tgatgtagaa cgtcgtccca agacggaatg gttctatttt aatggaactc
      901 ctgaaaaatc aaaaaatctt tttgataagt ttgttcagca tgatttgtct ggttatcagc
      961 ctggaaaagg acaggactat actctgcgac aagagcaaga agaagcagtt gctaagacat
     1021 tagcttattt ccaagaacat gctggaggca agtttctctg gaatgccaag ccacgctttg
     1081 gtaaaacctt gtctacctat gacctagctc gacggatgga agctgtcaat gtcctaattg
     1141 taacaaaccg ccctgccatt gctaactcat ggtatgatga ttttgaaaca ttcatagcag
     1201 gtcaaacgac ttacaagttt gtttctgaat cagatagcct taagagtcgt ccaatcttgt
     1261 cacgacaaga atttcttggt attttagctg acgatgtaag acaacttgct tttatcagtc
     1321 tccaagactt gaaaggatct gtttatttag gtggagagca cgataaactc aaatgggtaa
     1381 ctgatctgca ttgggacttg ttggttattg acgaggctca tgaaggagtt gataccttca
     1441 agactgacca agcctttaat aagattcgac gaaattttac tctgcatttg tcaggtacat
     1501 catttaaagc attggctaaa ggagatttta cagaggaaca aatctacaac tggtcttatg
     1561 ctgatgagca ggctgctaag tattcgtggt ctcttgagca agaagaggaa aatccttatg
     1621 aaagcttgcc tcagttgaat ctctttacct atcaaatgtc tcagatgatt ggcgaaaagt
     1681 tagaaaaagg cgctcagatc gatggtgaaa atattgacta tgtttttgac ttaagtgaat
     1741 ttttcgctac agatgataaa gggaaattta ttcatgagca tgatgtcaga aattggttag
     1801 atactctatc aagcaatgaa aaatatccat tttcaaccaa agaactccgt aatgaactca
     1861 agcatacttt ttggctttta gaacgtgtcg cttcggccaa agcattaaaa gccctactag
     1921 aagaacaccc aatctatgaa aactatgaga tcgttctagc tgctggtgac ggacgtatgt
     1981 ccgaagaaga cgataaagtc aaactcaaat ccttggactt ggttagaaaa gcgatagcag
     2041 agaatgacaa aaccattacc ctatccgttg gtcagctgac gacaggtgtc actatccctg
     2101 aatggacagg tgtattgatg ttatcaaatt tgaaatcacc agctctttat atgcaggccg
     2161 ccttccgtgc tcaaaatcct tactcatgga gcgataacaa aggaaatcac tttcgcaaag
     2221 aaagagccta tgtatttgac tttgcgccgg aaagaacctt gattctcttt gatgagtttg
     2281 ccaacaactt atcgcttgta actgcagctg gtagaggaac ttcagctaca cgcgaagaaa
     2341 atattagaga attattaaac ttctttccaa ttattgccga agaccgtgct ggtaagatgg
     2401 ttgaaattga tgcaaaggca gttctaacca ctcctcgcca gataaaagct agagaagttc
     2461 ttaaacgagg ttttatgtcc aatctcttat ttgataatat tagtggtatt ttccaagcaa
     2521 gtcaaacagt tttagatatt ttaaatgagc tgccagttga aaaggaaggg aaggtacaag
     2581 atagttctga tttattagat ttttcagatg ttacagtcga tgatgaggga aatgcagtag
     2641 tagaccatga aattgtagtt aatcagcaaa tgcgactttt tggtgaaaaa gtttatggac
     2701 ttggtgaatc tgttgctgag ttagtcacaa aagatgagga acgaactcaa aaacagctgg
     2761 tcaatgactt gagtaagacc gtttcttcag tgattgtaga ggaattgaaa gcagattatt
     2821 ctctaaaaac aagggaaact gagcaaatta agaaacaaat tacagcaaca cttgagaatg
     2881 aaattcgaaa aaatgatatc gaaagaaaaa tttctgaagc tcatatcaag caagagttgc
     2941 aacagcagct caaagaagca aatgataaag cgcaaaaaga taagattcaa gaagatttgg
     3001 aaaaacgttt agaagaaaat aaactcattc ataaagaaaa actagaacaa acactcaaaa
     3061 aagaagtgga aaaaatgcct gagaaattta tcgaacaggt tgagataaaa cgtgtggaac
     3121 agttgaaaca atcagctcaa gatgaaattc gtgaccattt acgagggttt gcaagaacaa
     3181 ttccaagttt tattatggct tacggtgatc aaactctaac acttgataat tttgatgcct
     3241 ttgttcctga acatgttttt tatgaagtaa cagggattac gattgatcag tttagatatt
     3301 tgcgagatgg tgggcaggat tttgcagggc atctctttga taaagcaaca tttgacgaag
     3361 ctattcaaga atttcttcgc aagaaaaagg agttggcgga ttattttaaa gatcaaaaag
     3421 aagacatttt tgactatatt ccaccgcaga agaccaacca aattttcact cctaaacgag
     3481 tggtgaaaag gatggtagat gatttggaaa aggaaaatcc agggattttt gatgatccat
     3541 ctaagacttt tattgattta tatatgaagt caggcctcta tattgcagaa cttgtgaagc
     3601 ggttatataa tagcaatggc ttgaaagagg cctttccaaa tcctgaagaa cgcttaaaac
     3661 atattttgga aaagcaagtt tatggatttg ctccgtctga gattatctat aacatttcca
     3721 ctaattttat atttggcaat ctttctaaag atatcagtag gaagaatttt gttttagcag
     3781 ataccattcc agcggctaaa gaagggagca ttcaaaagtt ggttgattcc tattttgaaa
     3841 ataattaaaa agaaggccga gtcaaaattc tttgaaatca gaaaaaacgc ataatattga
     3901 gtgcttttgt actgcccccc caaaagttag acagaaaaaa tctaactttt ggggggcagt
     3961 tcagacaatc cttggtatta tgcgttttat tgtgggaaga tgtataatgg attgaaataa
     4021 gatatgaaca aatcgattag gaatttaaag cattttataa caacgtttta gagtaacggg
     4081 gtactatttc atataataca ggaaaaaaca actccctgat gattcaagga gttgtctata
     4141 gttaaattag tttttagaag cttcttggaa ttctggattt ttccatgctt cgtcaataat
     4201 agcttgcaat tctttagcag atgcttgcat tttttgagtt tctgcatcgt tcaatggaat
     4261 gtttactgga cgaacgatac catgtgcacc aacaacagct ggttgaccga taaagacatt
     4321 ctcaactccg tattgacctt cttggaatac tgaaagtgga agtactgcgt tttcatcgtc
     4381 aaggattgct ttagtgatac gagcaagggc tactgcgata ccgtagtatg ttgcaccttt
     4441 tttgttgatg attgtgtagg ctgcatcacg aacaccttcg aacaattcaa tcaattcagc
     4501 ttcttgaaca ttttgagtgt ctttaaggaa ttcttcaagg tttacaccag cgatgttagc
     4561 gtgtgaccaa acagcgaact cagagtcacc gtgttcaccc atgatgtagg cgtgcactga
     4621 acgagcatcc acatccaatt tttcagcaag tgcttgacgg aaacgagctg agtcaagtga
     4681 agtacctgaa ccgataacgc gttctttagg gaaaccagag aatttccaag ttgagtaagt
     4741 caaaacgtca actgggttag cagcaacaag gaagatacct ttgaaaccag attcaacaac
     4801 ttgagttacg attgatttgt tgatagcaag gtttttacct acaaggtcaa gacgagtttc
     4861 acctggtttt tgaggtgcac ctgcagtgat cacaacaagg tcagcgtctg cacagtcaga
     4921 gtattgagct gcatagattt ttttaggtga agtgaaggca agggcgtgac taaggtcaag
     4981 cgcatcacca acagcttttt catgcaattg tggaatttcg ataattccaa gctcttgtgc
     5041 aattccttgg ttaacaagtg caaaagcgta agatgaacct acagcaccat caccgacaag
     5101 gataactttt ttgtgttgtt tagttgaagt cattgtttta aacatctcct taattttatt
     5161 aggggatttt ccctagacaa cttcattcta tcacttttaa aaaactttgt cacgaatatg
     5221 ccttatagtt ctcgatgtaa acgttttagt ggtttagagg ctgaaataga tgggaattta
     5281 tggtataatg ttgttactta ctaattgtga aatgaggcat ttattaatgc aggataaaaa
     5341 tttagtgaat gtcaatctga caaaggagat gaaggcaagt tttatcgact acgccatgag
     5401 tgttatcgta gcgcgagctc ttcctgatgt tcgagatggc ttaaaacctg ttcaccgtcg
     5461 cattctctac ggaatgaatg aattgggtgt gaccccagac aaaccccata aaaaatctgc
     5521 tcgtattaca ggggatgtca tgggtaaata tcacccacac ggggattcct ctatttatga
     5581 agccatggtc cgtatggctc aatggtggag ctaccgttac atgcttgtag atggtcatgg
     5641 gaattttggt tctatggatg gagatagtgc tgccgctcaa cgttataccg aggcacgtat
     5701 gagcaagatt gctctggaaa tgcttcgtga tatcaacaaa aatacagttg atttcgttga
     5761 taactatgat gccaatgaac gggaaccctt ggtcttgcca gcgcgttttc caaacctttt
     5821 ggttaatgga gcaactggta tcgcggttgg gatggcaacc aatattccac ctcataatct
     5881 gggtgaaacc attgatgtag tgaagttggt catggataat cctgaagtga ctaccaagga
     5941 cttgatggaa gtcttgcctg gaccagattt tccaactggt gctcttgtca tggggaaatc
     6001 aggtatccat aaggcttatg aaacaggtaa aggttcgatt gtcctacgtt ctcgtacaga
     6061 gattgaaacg actaagactg gtcgtgagcg catcgttgta acagaatttc cttacatggt
     6121 caataaaacc aaggtgcatg agcatattgt tcgcttggtt caggaaaaac gcattgaggg
     6181 tatcacagca gtacgtgatg agtcaaaccg tgaaggtgtt cgatttgtta ttgaagtcaa
     6241 gcgcgacgcc tcagccaatg ttattctcaa taacctcttc aaaatgaccc aaatgcaaac
     6301 caattttggt ttcaatatgc tcgctatcca aaatggtata ccgaaaattt tgtctcttcg
     6361 tcagattttg gatgcttata tcgagcacca aaaagaagtg gttgttcgtc gtacacgttt
     6421 tgataaggaa aaagcggaag cgcgcgctca tatcttagaa ggtctcttga ttgcgctaga
     6481 ccatatcgac gaagtgattc gtatcatccg tgctagtgaa acggatgcgg aagctcaagc
     6541 tgagttgatg agcaagttta agctttctga acgtcaaagt caagctatcc ttgatatgcg
     6601 tcttcgtcgt ttgacaggtt tggaacgcga taagattcaa tctgagtatg aagacctctt
     6661 ggctctgatt gcggatttag cagatattct tgctaagcct gaacgtgttt ctcaaattat
     6721 caaagacgaa ttggatgaag ttaaacgtaa attttctgat aaacgccgta cagagttgat
     6781 ggttggacag atcttgagtc tcgaggatga ggacttgatt gaagaatcgg atgtcttgat
     6841 taccctttct aacagaggct acattaagcg tttggatcag gacgagttca ctgctcaaaa
     6901 acgtgggggt cgtggtgtcc aaggaacggg agtgaaagat gatgactttg ttcgtgagtt
     6961 agtgtcaact agcacccatg atcatctgct cttcttcaca aacaagggac gtgtctatcg
     7021 tcttaaaggt tatgaaattc ctgagtatgg tcggactgcc aaagggctac cagtagtcaa
     7081 tctcttgaaa ttggatgaag acgaaagtat tcagacggtt atcaatgttg agtctgatcg
     7141 cagtgatgat gcttatctct tctttacaac ccgtcacggt attgtgaaga gaaccagtgt
     7201 taaggagttt gccaatattc gtcaaaatgg tctcaaagcg ctgaatttaa aggatgaaga
     7261 tgagttaatc aatgtcttgt tggcagaagg agatatggat attatcattg gtaccaagtt
     7321 tggttatgca gttcgcttta atcaatcagc cgttcgtggt atgagtcgta tcgccactgg
     7381 tgtgaaaggt gttaaccttc gtgaaggaga cacagttgtt ggtgccagct tgattactga
     7441 tcaagatgag gttcttatta tcacagaaaa aggatatggt aagcgtacag tcgctactga
     7501 atacccaaca aaaggtcgtg gtggtaaggg aatgcagaca gctaaaatta ccgaaaaaaa
     7561 tggcttgctg gccggtctta tgactgttca aggggatgag gatttgatga ttatcactga
     7621 tacaggtgtc atgattcgaa ccaatcttgc caatatttca caaacaggac gtgcaactat
     7681 gggagttaaa gtaatgcgcc tggatcaaga tgctcagata gtgactttca caacggttgc
     7741 ggtggcagaa aaagaggaag ttgggacaga aaatgaaaca gaaggtgaag cataatgtct
     7801 caaaaaaata ataaaaagaa aaacaagcga aaaaatctgc tgacaaatat cctagcagga
     7861 tttctgatat tactgtcact ggctttgatt tttaatactc aaattcgaaa tattttcata
     7921 gtctggaata ccaataagta tcaagttagc caggtatcaa aagagaaatt agaagaaaat
     7981 caggatacag aaggcaattt tgactttgat tctgtcaaag ctatctcttc ggaagctgtt
     8041 ctaacttctc aatgggatgc tcaaaaatta ccagttattg ggggaattgc aattcctgaa
     8101 ttggaaatga atttgccgat ttttaaagga cttgataatg ttaatctctt ctacggagct
     8161 ggtacaatga aacgcgagca agtaatggga gaaggaaatt atagtctagc tagtcaccat
     8221 atctttggtg ttgataatgc taataaaatg ttattttctc ctttagataa tgctaaaaat
     8281 ggcatgaaga tttatctaac cgataaaaat aaagtttata cttatgaaat acgtgaagtc
     8341 aaacgtgtga caccggatcg tgttgatgaa gttgatgata gagatggggt caatgaaatc
     8401 acattagtaa cctgtgaaga ccttgctgct acagaacgta ttattgtcaa aggtgatttg
     8461 aaagaaacaa aagattattc acaaacatct gatgaaatcc taacagcttt caatcaacca
     8521 tataaacaat tttattaata caaatcagtg aaatcatgga tttcactgat tttttaagat
     8581 tttcata
//
LOCUS       DAVLTT010000072         8497 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLTT010000072 DAVLTT010000000
VERSION     DAVLTT010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8497
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.072"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            106..1167
                     /gene="dinB"
                     /locus_tag="VYN15_001841"
     CDS             106..1167
                     /gene="dinB"
                     /locus_tag="VYN15_001841"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV1453122.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            complement(1314..2159)
                     /locus_tag="VYN15_001842"
     CDS             complement(1314..2159)
                     /locus_tag="VYN15_001842"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV1453123.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            2414..3432
                     /locus_tag="VYN15_001843"
                     /pseudo
     CDS             2414..3432
                     /locus_tag="VYN15_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(3733..5622)
                     /locus_tag="VYN15_001844"
     CDS             complement(3733..5622)
                     /locus_tag="VYN15_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV1453124.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLLAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKEQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            5760..7325
                     /locus_tag="VYN15_001845"
     CDS             5760..7325
                     /locus_tag="VYN15_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1453125.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYISEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGF
                     KTGEEDTAIAIGLRKDDTRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTITGLIIGLAIGVFRTAPLSENKVIYS
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAAHALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            7325..8065
                     /locus_tag="VYN15_001846"
     CDS             7325..8065
                     /locus_tag="VYN15_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1453126.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(8174..8389)
                     /locus_tag="VYN15_001847"
     CDS             complement(8174..8389)
                     /locus_tag="VYN15_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453127.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
BASE COUNT         2695 a         1865 c         1580 g         2357 t
ORIGIN      
        1 aaactaggaa gctagccgca gattgctcaa aacactgttt tgaggttgca gatagagctg
       61 acgtggtttg aagagatttt cgaagagtat aaaaaggtgc taggcatgtt gatttttcct
      121 ttgttaaatg atttgtcaag aaaaatcatc catattgaca tggatgcctt ttttgctgca
      181 gtggaaatca gggataatcc taaactcaga ggaaaacctg tcattattgg aagcgaccct
      241 cggcaaacag gtggacgggg agtcgtttct acctgtagtt atgaggcaag agcttttggt
      301 gtccattctg ccatgagttc caaggaagct tatgaacgtt gtccccaggc tgtctttatc
      361 tcagggaatt atgagaaata caagtctgtg ggactccaga ttcgagctat ttttaagcgc
      421 tatacagatt tgattgaacc catgagcatt gacgaagcct atttggatgt gacagaaaat
      481 aaactcggta tcaagtcagc ggtcaaaatt gctcgcctca ttcaaaaaga tatctggcaa
      541 gaactccatc taactgcttc cgcaggcgtt tcttacaaca aattcttagc taaaatggcg
      601 agtgattatc aaaaaccaca tggtttgaca gtgattctac ctgaacaggc tgaggatttt
      661 ctcaaacaaa tggatatttc caaatttcat ggagtaggaa aaaagacagt agaacgtctt
      721 catcaaatgg gcgtttttac tggtgctgat ttacttgaag ttcctgaggt aaccctaata
      781 gaccgttttg gtagactagg ctatgatctg tatcgaaagg ctcgtggcat tcacaactct
      841 ccagtcaaat ccaatcgcat ccgtaaatca atcggcaagg agaaaaccta cgggaagatt
      901 ctccttgctg aggaagatat caaaaaagag ctgactcttc tatcagaaaa agtcgctctc
      961 aatctacatc aacaagaaaa agctggaaaa attgtcattt tgaaaatccg ctacgaggac
     1021 ttttcaactc ttaccaaacg aaaaagtctt gctcaaaaaa cacaagatgc tagtcagata
     1081 agccaaatag ccctgcaact ctatgaagaa ttaagcaaga aagaaagagg tgtccgccta
     1141 ttggggatta ccatgactgg attttaaagc tcaatgaaaa tcaaagagca aactaggagg
     1201 ctagccgcag gctgctcaaa acactgtttt gaggttgcag ataaagctga cgcggtttga
     1261 agagattttc gaagagtata aaaccttgaa gagttgcccc ttcaaggttt ttcttataca
     1321 aataaacgga caaaactgta aagtagcaaa acactaccaa gcacgatacg gtatttacca
     1381 aaaagggtga agtcgtgttt tttcacatag ctggtcaaga agcgaatagc caccatgctg
     1441 accgcaaaag ctactcccat cgcgaccaag agcaaaaaca attgcccaaa gctcaagagt
     1501 tctccggctt tcacaaattt gaaaatcttt aaggcactag ctccaaacat aacaggaatc
     1561 ccaagataga aggtaaattc tgtcacaact gaacgactgg ttccatttaa caaaccaccg
     1621 acaatcgttg cacctgaacg gctagtccct ggtaaaagag caagaacttg gaagagtccg
     1681 atatagaaag cggtcgtata aggaagcttg tccaactctg ttacacttgg ctcgatagca
     1741 cgcgctttat tgcgcttttc caaatagatg aaggcaaccc cgtagataat caacatgaga
     1801 gcaactgaaa ccatgttatg gaagtgggta tcaaaccaat catcaaattt aaagacacca
     1861 agtaaaggta aagtagcaat caagaccttc aaccatagtc tccaagtctt acgaacttcc
     1921 tgtttgtcct tggtcggttt aaaaggattg agcttgttaa aataaatcac cataactgct
     1981 aaaatagcac caagctgaat cacgacatta aacatggaca taaaggcttc attttgattt
     2041 tggtattgga tgaattcctc tgctaaaatc aagtgacctg tactggaaat cggcaaccat
     2101 tccgtaattc cttcaacaat tccgaagaag atagatttta aaatttcaat aagatacata
     2161 gattactccc tatattatat ttagcgcagt tagctactgc caaagcccaa gtggtatact
     2221 tggaataagc cactatggat tagttcattt cctccaatcg cttgacgatt tccgaaaggc
     2281 tctaaccaca gcttttgttt caattggtaa tgagtttgat aacgcataga cgtttgatct
     2341 cgtctaaggt aacaaggcaa aaaattcgtg gataaccaag tagacttgaa atactatatc
     2401 tggaggtact cccatgcttt atgtaggcat tgatatcgct aaaaataaac acgatgttac
     2461 agccttgaat gttccaggaa aaactgttct taaaccactc actttttcaa ataataaagc
     2521 tggttttgaa ctcttagatc tgtctattcg acagatcaac caagactgtc tcatcgctct
     2581 tgaagatact ggacattatg cctttaatct actgaacttc ctgcatgaac aaggatataa
     2641 agtttacacc tacaatcctt tgctcatcaa ggaatttgcc aaatcattat cacttcgcaa
     2701 gactaaaacg gataagaaag acgctcatgg catcgctctt aaacttcttt ctgaccccaa
     2761 tcgtgaacaa tttcaacacg ataatcggca agtagaccta aaaatactgg ctagacatat
     2821 tcatcgtctc aagaaaaaca gtctgattgg aaagtacaat acactcgttg tcttgatatc
     2881 atctttcctg agttggataa aatcgttgga aagcattcag aatataccta ccaactcttg
     2941 acacgctacc ctaatcctca gaaaaggatt gaggcaggat ttgataagct gatagaaatt
     3001 aagcgattga ccgcttctaa aattcaggat atcctctcag tcgcacctcg ttctatcgga
     3061 acaacatctc ctgctcgtga attcgaaatc atcaaacatt acaagaggct cattgacaag
     3121 gcggaaacat gtgtcaatga cttgatggct gagttcaact cggtcatcac gacggtcact
     3181 gggattggga atcgtttagg ggcggtcatt ttagccgaga ttcgaaatat tcatgccttt
     3241 gataatcctg ctcaattaca agctttcgct ggactggatt cttctattta tcagtcaggt
     3301 cagattgatt tagctggaag aatgatcaaa cggggtcccc ctcatctgcg gtgggcactc
     3361 atacaagctg ccaaagcatg cgctcgcttt tcacctgctt ttaaggccta tcttaagact
     3421 aagttagaat aaggaaaaca ttacaatgta gccatcatcc accttgcaaa aaaacttatc
     3481 cgaaccctgt tttatatcct aaaaaagagc tgccatttga cgaacaaaaa gtgatgtaat
     3541 ttctgaaatt aacacaggat tacctttgaa aaaatggact ttttcaaggg ctttttgccg
     3601 tgctctaaaa tcatcgccaa atcatcaaat tgaaataaga aatagtttag ataaaactat
     3661 tgacttttct tatagtttgt ctttcttcta tcttccatta tatcatactt tttcagtcta
     3721 tggtagctct ctttaaaagg ctccgatact gccgccacct ccgcctccag agaagccacc
     3781 gccagaactt ccacttccag aagatacgga gtaggtactt gctgtatttg cgacactagc
     3841 ataatggctc atttgcgcgc ttgaatgata aaacatactg tgccagccat aagctacata
     3901 gagattgata tctggatttt caacttgaat ctgatgaacc ttcatcaaat gactaacctt
     3961 gtccgcatag ccaaataagg ttgcatagac caagagacga ttccaaacaa caatactttc
     4021 caattcagcc ttatccagtc gtgcaatctc acgtaacata ttttcaaaac tggtccagag
     4081 atagtagacc tcagctcccg cttcatttag aacaccatca cgattatcta gtcgaagctt
     4141 ccaataatag aaaacagaca aaactaaccc tagaaaacca agtattggca aagggaggta
     4201 aagatagcca tgaacgtcta aactgtacaa gaacaaacca aatccgataa ataggggcaa
     4261 gatagtcaag acacccatac ccacttgcaa agccttttcc aaaccagtta aaggacgata
     4321 gtaatctggg agcccccaga aggaaactcg ttttctcact ccttcttgca tctggttcaa
     4381 tacctcttca aaagaagatt tgagttgaag ccctcttgct tgaatccgtt tttcatcaga
     4441 aactttggct ctacgataaa gactatcaga taccttgtaa tccgcaaaca aattggaaag
     4501 agtttcttct tttttacctg aaaaagctag atttaggcag tctttctcaa agcttgacaa
     4561 accatcttct tttactagcc tcaaaccaac tgcatctcct tctgaaatga tagagacatt
     4621 cccacggtct atcacatcta gcaaggtagc ttgaataagt tgatcaaagg tgaattttcc
     4681 agctcccttg accaagggac tcacttcctc caaggaggtc gagtagactg cttctgataa
     4741 aaccataggc tctaattcca ttgggggttc atagagacga tgatttttag catatttgat
     4801 tgaaggagcg gtctttcttc tatagataaa atagaaacag atgctcaata acaaggagat
     4861 ggaaaggatc gaagggaaga tccaagtaag tagttgttta ctttgctctt tttctttaac
     4921 gatcgaatcc tctatcttat taaactcttc taaacgattc cctttcaagc cctgatccct
     4981 agcgctagca aaatcagttc gcggccagta ggcatgcaat tcaactccac gcttagccag
     5041 aagattgtct aaacgaatag tataatcaag gttactcttt tcaaccgttc tctctctaaa
     5101 aagtttccct gtatggaaaa agagtttctc agcccccttg tctcccctta catgaaattc
     5161 aaacttttca atagactctg aactatctgt cagaggttgc caatttaatt cagcgatatc
     5221 atcataaagg aaaagtaaat tttttaagtt ccaaacgagg tcaacttcaa ctatgtcgcc
     5281 ctcctgacct ggattataga ctctcacagt ataaccatcc gcttcttctg ttacttcgct
     5341 agtcacatct gctagttctg caccgttttt cgcggcctga atctttggat gagggtcaat
     5401 gtcaaacccg ctaggcatct taccagcacg tccaagtccc acgatttggc ccttaaagtc
     5461 ctcctcaaac tggtaaacta tcttctgtct aaactctgcc gtattgtctg catgaatata
     5521 caaatcccct tgataagagt ttatcttgaa atcaatggca aaaacagaga gtggaagaag
     5581 gcaaaacaag cctaacacca gtaagaaaaa agtttttttc atcaactaag cccccttttt
     5641 atctttctta tcattatagc attttttcgt aagtaaagac ttacttatgt tgaaaaatta
     5701 cgcatttttc gataaaatag gagacagtta ttttttaata gatcagaata ggagaaatca
     5761 tgagaaaaat atacttatct attttcacaa gtctcttgct gatgctagga cttgtcaatg
     5821 ttgctcaagc cgatgaatat ttacgcatcg ggatggaagc agcatatgct ccctttaact
     5881 ggacccagga tgatgatagc aacggagctg tcaaaatcga tgggaccaat cagtatgcca
     5941 acggatacga tgttcaaatc gccaagaaaa tcgctaagga cttaggtaaa gaacctttgg
     6001 ttgttaaaac caagtgggaa ggtctagtcc ctgcccttac ttctggtaag attgacatga
     6061 ttatcgcagg tatgagtcca actgcagaac gcaaacaaga aattgccttt tcgagcagtt
     6121 actacattag cgaaccagtt ctactggtca aaaaagattc tgcctatgca agtgctaaat
     6181 ctttggatga ctttaatggt gcgaaaatca cttctcaaca aggggtctac ctttatgact
     6241 tgattgcaca aatcacaggt gctaaaaaag aaacagccat gggagacttc gctcaaatgc
     6301 gccaagctct tgaggctggt gtcatcgacg cctatgtttc tgaacgccca gaagctctga
     6361 ctgccgaagc cgctaactct aagttcaaga tggtccaagt agaaccaggt ttcaaaactg
     6421 gggaagaaga tacagctatc gccattggac ttcgtaaaga tgacactcgt attagccaaa
     6481 tcaatgccag cattgaaacc atttcaaagg acgaccaagt tgccctgatg gatcgtatga
     6541 tcaaggaaca acctgccgaa gctacaacaa ctgaagagac tagcagtagt ttctttagcc
     6601 aagttgctaa aattctttct gaaaactggc aacaactctt gcgtggtgct ggtatcactc
     6661 ttttaatctc tatcgtcgga accatcacag gtctcattat tggacttgcc attggtgttt
     6721 tccgtactgc tcctctctct gaaaacaaag tcatttacag cctacaaaaa ctagtcggct
     6781 ggatcctcaa cgtctacatt gaaattttcc gtggtacgcc aatgattgtt caatcgatgg
     6841 ttatctacta tggaactgcc caagctttcg gtatcaacct tgaccgtaca ctggctgcta
     6901 tcttcatcgt ttcaatcaat accggtgcct acatgactga aatcgtccgt ggtggtatcc
     6961 tagcagttga caagggacaa tttgaagctg cgcatgctct tggtatgacc cataaccaga
     7021 ccatgcgtaa gattgtccta cctcaggtag tccgtaacat cctacctgca actggtaatg
     7081 aatttgtcat caatatcaaa gatacatctg tattgaacgt tatctctgtt gtcgaacttt
     7141 atttctcagg aaataccgtg gcaacacaaa cctatcaata cttccagaca tttacaatca
     7201 tcgccgtgat ttactttgtc ctcaccttca ccgtaacacg tatcctacga tttatcgagc
     7261 gccgaatgga catggatacc tatactacag gtgctaacca aatgcaaacg gaggatttga
     7321 aataatgaca caagcaatcc ttgaaattaa acacctcaaa aaatcctatg gacaaaacga
     7381 agtgctaaaa gacatttcac tcactgtcca caagggagag gtcatctcta tcatcggaag
     7441 ctctggaagc ggaaaatcga ccttcctacg ctccattaac ctacttgaaa caccaactga
     7501 tggacaaatc ctttatcatg gacaaaacgt cctcgaaaaa ggctatgacc tcacgcaata
     7561 ccgtgaaaag ttggggatgg ttttccaatc ctttaacctc tttgaaaatc tcaatgttct
     7621 tgaaaacaca atcgtcgctc agacaactgt cctaaaacgc gaacgcacag aagctgaaaa
     7681 gattgccaaa gaaaacctgg aaaaggtcgg catgggagaa cgctactggc aagccaaacc
     7741 aaaacaactc tcaggtggtc aaaaacaacg tgtggccatc gctcgtgccc tctccatgaa
     7801 tccggacgct attctctttg atgaaccaac atcagctctc gatccagaaa tggttggaga
     7861 agtcctcaaa atcatgcagg acctagctca ggaaggcttg accatgattg tcgtaaccca
     7921 tgaaatggaa tttgcccgtg atgtctctca ccgtgttatc tttatggata agggcgtgat
     7981 cgctgaagaa ggtaaaccag aagacctctt caccaatcct aaagaagacc gaacaaaaga
     8041 gttccttcaa cgctatctca aataaaaaga aaaggctgca tcaaccgtgc agtctttttg
     8101 ctgtcctcaa aataaaaagg cagattctct atctctacta cttgaaggtc aagaatccgc
     8161 cgttatccaa agattaatct tcaaattttt cataattttt ttcatagaaa tcaattaggc
     8221 ctagggctgt ttcaaatgaa atatttttta cttttgcacg accctgcgcc agagcaatga
     8281 tagacatttc acgcgcattc gtttctttag agatacggta gcctgtgatt ttcttatcac
     8341 gaacccagcc aacaactgat tctacttttt caaagtttga cttagccatg tttttctcct
     8401 attttcttct ttataatatt taattgtata cgtttttact acttttgtca ataaaaaaaa
     8461 catatattca acgaaaataa ttagttcaga attttct
//
LOCUS       DAVLTT010000073         8448 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLTT010000073 DAVLTT010000000
VERSION     DAVLTT010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8448
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.073"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            143..1333
                     /locus_tag="VYN15_001848"
     CDS             143..1333
                     /locus_tag="VYN15_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV1453128.1"
                     /translation="MKSIKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKRVHFYYSFRGEENAVYLDLLRDYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCSPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(1654..2535)
                     /locus_tag="VYN15_001849"
     CDS             complement(1654..2535)
                     /locus_tag="VYN15_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV1453129.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(2676..4004)
                     /gene="vncS"
                     /locus_tag="VYN15_001850"
     CDS             complement(2676..4004)
                     /gene="vncS"
                     /locus_tag="VYN15_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV1453130.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGDTMILQFLASMDLQKEAEQISLQFLPYTLLTSFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(4001..4657)
                     /gene="vncR"
                     /locus_tag="VYN15_001851"
     CDS             complement(4001..4657)
                     /gene="vncR"
                     /locus_tag="VYN15_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV1453131.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(4706..4789)
                     /gene="pep27"
                     /locus_tag="VYN15_001852"
     CDS             complement(4706..4789)
                     /gene="pep27"
                     /locus_tag="VYN15_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV1453132.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(4969..6348)
                     /gene="vex3"
                     /locus_tag="VYN15_001853"
     CDS             complement(4969..6348)
                     /gene="vex3"
                     /locus_tag="VYN15_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV1453133.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(6400..7047)
                     /gene="vex2"
                     /locus_tag="VYN15_001854"
     CDS             complement(6400..7047)
                     /gene="vex2"
                     /locus_tag="VYN15_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV1453134.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKAGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(7060..8337)
                     /locus_tag="VYN15_001855"
     CDS             complement(7060..8337)
                     /locus_tag="VYN15_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1453135.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITSYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         2400 a         1840 c         1602 g         2606 t
ORIGIN      
        1 agccactctc cagttcaatt ggagagtttt tttgatgaga gtagatattt ataaacctca
       61 atttgacacc atacattttc tatgataaaa tgtaacaaat ttatttacaa caaatcgaaa
      121 tctaaatgaa atggaatttt ctatgaaatc aatcaaagga ctactcttta tcatagctag
      181 ttttatcttg actcttttga cttggatgaa cacttctccc caattcatga ttccaggact
      241 agctttaaca agcctatctc tgacttttat cctagccact cgtctcccac tactagaaag
      301 ctggtttcac ggtttggaga aggtctacac cgtccacaaa ttcacagcct ttctctccat
      361 catcctacta atctttcata actttagtat gggcggtttg tggggctctc gcttagctgc
      421 tcagtttggc aatcttgcca tctatatctt tgccagcatc atccttgtcg cctatttagg
      481 caaatacatc caatacgaag cttggcgatg gattcaccgc ctggtttacc tagcctatat
      541 tttaggactc tttcacatct acatgataat gggcaatcgt ctccttacat ttaatcttct
      601 aagttttctt gttggtagct atgccctttt aggcttacta gctggttttt atatcatttt
      661 tctatatcaa aagatttcct tcccctatct agggaaaatt acccatctca aacgcttaaa
      721 tcacgatact agagaaattc aaatccatct tagcagacct ttcaactatc aatcaggaca
      781 atttgccttt ctaaagattt tccaagaagg ctttgaaagt gctccgcatc ccttttctat
      841 ctcaggaggt catggtcaaa ctctttactt tactgttaaa aattcaggcg accataccaa
      901 gaatatctat gataatcttc aagccggcag caaagtaacc ctagacagag cttacggaca
      961 catgatcata gaagaaggac gagaaaatca ggtttggatt gctggaggta ttgggatcac
     1021 ccccttcatc tcttacatcc gtgaacatcc tattttagat aaacgggttc acttctacta
     1081 tagcttccgt ggagaagaaa atgcagtcta ccttgattta ctccgtgact atgctcagaa
     1141 aaatcctaat tttgaactcc atctaatcga cagtacgaaa gacggctatc ttaattttga
     1201 acaaaaagaa gtgcccgaac atgcaaccgt ctatatgtgt agtcctattt ctatgatgaa
     1261 ggcacttgcc aaacagatta agaaacaaaa tccaaaaaca gagcttattt acgaaggatt
     1321 caagttcaaa taagtaatca tactctcctg ggaaatccca ggagagtttt ttatagccaa
     1381 atgaaataag acaggaacga tggaattttg gcattcaaat caattgataa gaatgtttta
     1441 tagtggagtg aaataggata cgaacaaatt gattaggaaa atcaaatgaa tttatagaaa
     1501 tcttttagca gttatgttat cctattctag tttcaaaacg ctatagaagc agcattgtgc
     1561 tagtctagat tcagtttact atactaaaac gagtagcttg aaatcaaaaa acccaccctc
     1621 acaggcaggt tttatctgta ttattcagct agattatgct ttaccttctg aaccgaatac
     1681 gtcgatacgt tcttcaaccg atgcttggat agcttttaca ccgtcagcca agaatttacg
     1741 tgggtcgaag agttttttct tgtcgtattc tgcttcgttt gcttcgtagt cacgagcaaa
     1801 tttacgagtt gcgttagcga atgcgatttg gcattctgtg ttaacgttaa ctttggcaac
     1861 accaagtttg atagctgctt ggatttgctc atcaggaata cctgatccac cgtgcaatac
     1921 gattgggaat cctggaagag cttctgtcaa tttttgcaag tggtcaaggt caagaccttc
     1981 ccagtttact gggtaaggac cgtggatgtt accgatacca gctgccaaga agtcgatacc
     2041 agtttcaacc attgctttag cgtcttcgat tggagccaat tcacctttac cgatgattcc
     2101 gtcttcttca ccaccgatag taccaacttc agcttctact gagatacctt tagcgtgtgc
     2161 tttttcaaca acttctttag ccaatttaag gttttcttca actggaaggt gtgaaccgtc
     2221 aaacatgatt gaagtataac caacttcgat acactcaagt gcatcttcgt agtgaccgtg
     2281 gtcaaggtgg atagctactg gtacagtgat acccattgat tcaacaaggt tagcgatcaa
     2341 gttgcgagca actttgtaac cacccatgta tttagcagca cccattgaag tttggatcaa
     2401 aactggagct tttttagctt ctgctgcgcg caagatagct tgagtccact caaggttgtt
     2461 tgtgttaaat ccaccaactg cataaccgtt gtcacgggct gcttggacaa atttttctgc
     2521 tgaaacgatt gccattttat caggcctcct gtatattttt atgggtcatc ccatttacat
     2581 tgttcatttt atcacttttt gccaaaaaaa tctagttttt cccgcagttt cgattgattt
     2641 tcttctaact ccatctatgt aaaccctttc tctccctagt cttggacgac ttttggaaaa
     2701 tctataaaga aggttaaacg attctcctcc atctcgaaac gataagctaa tttttcatgt
     2761 tctaatagac tcttaaccac aaagagcccc ataccagacc ccttgacctt gcgactagca
     2821 ttgtcagaaa aagactgggc tagtttttct tgttcctctg agctacagct attttcgata
     2881 aaaagttctc cttctctttc tccaattcga actaagccac ctggaacaga gtgcttaatg
     2941 gcattgctga tgagattaga aagaatcaac ttcataactg atgggtttag ataagcctgc
     3001 tgatgggtca aactattgtc tatctggagc tctctttcct ttgctagcaa ggcataatct
     3061 ttgaccagat tttgcgtcat ctggaggagg tcaattgttt ccctatcatc tcgcaattcc
     3121 tgcacagaag agagggaaag tatctgcaga acatggtgat tgagttcatc cacaatcccc
     3181 aaggcaactc ccagatactg gtctctatcc ttataacgac cgatattctc tctcatattt
     3241 tcgattagga ttttcaaact agccagcggt gttttcaatt catgagaagc tcctcgtagg
     3301 aattcgacct tcatcttctc cagctggaga atggcttcat tcttttcatg caagtccgca
     3361 ataacagtca agagatgctg gtagaggcta ttgatttgtt ccttgagatt acctatctca
     3421 tccttagaat ccacgcgcaa tcgcacttgg gaatccaggt ccatcatccg acgggtcacc
     3481 cgcttgattt ccaaaatcgg tgcaacaata gtccgagcgt agatgtaggc caccaagagg
     3541 gaaatcagaa aggaggtcag caaggtatag ggaagaaact ggagactgat ttgctccgct
     3601 tccttttgta aatccatgga agctagaaac tggagaatca tagtatcacc gtcttgcgtt
     3661 ttcacctcgc gctcctcaat aaagagagag gttgtctggc ggtctgtgtc cagaggaaga
     3721 ctgtccttga cttctaactt gtcctcggtc atctcacctt tgacggtccc cttgatatca
     3781 ctagtctggg aatacaagtc taacacttgc tcgatactct gcctatcttt cccttctagg
     3841 gactgggcaa tggctgttgc cttttgacca atggtttcct gacgatgact cagataagtc
     3901 gaaggaaaaa gaaaataaat agctaaatga aggcagataa ccagaacact aaatatcgag
     3961 aaggtataga taaatatctt tgcaaataaa cctgttcgtt tcattttcgc tccaatttat
     4021 aaccaacatt gcgcacagtg aggatacaat ccaagtctag ctttttccgc aattccttga
     4081 tataaacatc aataacacgg tcaaagggaa cctcatctgt cgctttccag acggcatcga
     4141 taatctgaga ccgagtcaag gcccggcctt catttttcac tagatagtcc agaatttcca
     4201 actctttggc attgataggc acttcttgac ctgcgaggct tgcactgtag ctttcaaagt
     4261 ccaccttggt atccttgtaa gaaaagattc gtcctgtatc gtagtagcgc ttgaaaatcg
     4321 cgtccaccct cacttttaag agggagaggg agaaaggttt ttccagatag ccatctgcca
     4381 aagaggcaaa ggcactcatc ttgtattcct catcttgaaa agctgtcaac atcaagacag
     4441 gaacctgact ggttttacga atctcagcta ggacttctaa gccgttgagc ttgggcatct
     4501 ggatatccag taaaaccagg gccacctcat agctagaaaa ttgctccaga gcttcctgac
     4561 cgtccgctgc ctcaatagtt tcatagccac aatccgtcaa ataatcactg accccctcac
     4621 ggatcatctc ttcatcttct acaattaaaa ttttcatact ttaactgctc tctatttttt
     4681 atttttctta gaataaatac ctactctatt ttctattata gtctcttgct ggccttttgt
     4741 ctgtaagtaa ctgatcacta gataaaacgt tgtgaaattc ctttctcata aattccatag
     4801 ctttagtata ttatatttaa gcaataaagt acaaagaaaa caactgaaag caatgatttt
     4861 caccactgct ttcggattta ttttgaattg ttaaatagcc attcctatcc actattcttg
     4921 aatagaaaca caagatgcaa tctttattcc agactcattt tttcaaattt attcaccatc
     4981 cagcaagagc tcttttggtt gttttctaag gagattgctt gaagcaagcg ccataacgag
     5041 aaccactaga accaaggcaa ggacaaaaat gatgataaag tctgatgtct gaatagaaat
     5101 gtctaggctc gacaaggtct tgctaaagcc atctacttct gcaccaccac caaggttaga
     5161 ggcttgagcc gccttactag cctgtttggc aacacctgaa gtcacattgg caaggacagt
     5221 gtttccaatt gcacgggcag tgtaattagc taggaagtaa gcagaaacta gagcagggat
     5281 agcaatcaag atagattcgg tgatgaattg acccaagata cttgcctgct tgaggccgat
     5341 agagaggaga attcccactt ccttgcgacg ggcgttgatc caaaggctga gcaagagggc
     5401 aaggaggaga actgagaagc tcaagctacc ccagaagagg aggttggcca tcttgtacat
     5461 accagagata gattgctcaa gagctgggta gttagaggag ctcttgacga gtgtgtagct
     5521 cttccagttg ataccactga tgccattcaa ctctttcata acatcatcca agttcttgtc
     5581 tgctgttaca aagaaggttg cgtccccata aatggctgtg tcttctgtgt atccataaag
     5641 ttttgcagca gtgtgaatgt ctgtaatagc tgtgttttcg taaagttctt gtgagtaggt
     5701 tactgctgac ttattatgac catcaaagag tcccttgatt gtcacttcaa ctgtttcctt
     5761 ggctcctttt tcattatctg catcgtagat attagagtcc agtttaacct tgtcccctac
     5821 tttccagccg tgtttggctg ccaagtcctt gtgcaagagg attttatcct tgtcgtcgtt
     5881 ggttaagtgc tctccttcga ctagtttata agaaccagag acaaacttgt cttctttaga
     5941 ggagtcattg acacctgtaa tcatcaagct acttccaaaa cgtttggcac gatcagcagt
     6001 gagattcttc ttggtttctg gcgtttcaat caggtcatat ccagtcaaat ctccgatagc
     6061 gttgatacgt ttgacataag actcaatggc cttgttttcg gtgatttttt tgatgtcttc
     6121 acccttgata ttcccagcac cgcgaggcgt tccttggttg acgcgacgat tgatttgcat
     6181 ggagaagcta ttggtgatat ttttaaaggt ctcctgagaa gccttggcag tagctccctt
     6241 gattgacaag ccgaccaaac tcaagctcgc catgaggaga ataatcagga agatgacaat
     6301 cgatttgaaa aacttccttg taacataggc aaatgcgttg tgtaacatag attccctttc
     6361 tagattttgt tttaatcatt ctattaaaat aagctcaaat tatttactag tattgcgcgt
     6421 ttcagtcagt ttcttatcct ttaattcaag tgtaatatct gacgcttgtg ccacttcttt
     6481 actgtgagtt acgacaatca cacatttacc tgctttctgg gcaagtgatt tgagtagttc
     6541 gacaatatct ccagcagttt taggatccag atttcctgtt ggctcatcag ctagaataac
     6601 tggagcttct gagaccaaac tgcgagcaat ggcaacacgt tgctgttgac cacctgataa
     6661 ctggagaaca ttccgcttga tctggctttc atccaaacca agctcaagaa gtgtattctt
     6721 gcttgccttt ttgttgacca atcggatatt ttccagcgga gaaagataat ctatcaagtt
     6781 ataattttga aagaccaggg aaatatggtg catgcgatgg taagaatagc ccttcttacg
     6841 aatatcctct ccttgaaaaa ggatagaacc ttcaacagga ctatctagac cagcaagtag
     6901 ggacaagagt gtggattttc ctgctcctga ctccccaata atactgtaaa attttccggg
     6961 ttcaaaatta taattgatct gatataggac tgcttcagca gtattcttat aacggtaggt
     7021 aacatcttgt aattgtaata aagtcatgat ttctccttct taactaatag atgataaaat
     7081 ttctttcggt gattttctaa ataagaatag gaaacaaagg gctacagata agcaactaag
     7141 cagaactaga aaaacatagg attctgcaaa agataagatg ctagttgata aactgcttgc
     7201 tttggctagt gtatcttgta agcttgcctg atctccactt gctagtagag tttggagtag
     7261 gtaacttgtg attgcgtttc ctgcaacaaa tgctggaagc aaagctccaa gagataccaa
     7321 aactacctct aaacagaatt gtaggaagat cgagctcttg ccttttccaa gtgcaagtaa
     7381 aatccccact tcatagaccc gttctctcaa ccagagagac aaaaccagaa ttaaggctcc
     7441 agctcctgct atcaacatcc cataaaggaa gatggtcagg aaggtttgga aagttgcaac
     7501 tgagtctttg atttgttcaa aagccttgtt ttccttttcg acttggtagc cttgattttc
     7561 caaggccaag ttttctacct gcttcatgag tccgtccatt tccttaggat tttctacata
     7621 gaagcgtgct gcactgactt gagcttcact attgcccaaa agggtttggc tactttcata
     7681 gtctgtaaag acttgatttt cactgaagtc agaagacaag cctgtgaatt tctcttgttt
     7741 tttaccagaa aagatgccga taatctcaaa ctctactgtt tgtccttttc cagattcaga
     7801 ctgaccagca tccaagccaa tcttgtcatg aagcgaaaga ccgttcttct tagccaattc
     7861 ttcgtggata aggattttct tggaatcccc tttttgaagg tgtcgccctt cttttagatt
     7921 gaaagccgaa ctggtaaagg ttacatcctt ggatgaatcc tcaagagccg ttaagctaac
     7981 caagttattg tctgcagctg ataaatcatc acgctccacg ctctgctcgc cagtcactgc
     8041 ttccttgtct tttagttttg cgaccgtctc aagttcagga gagacatttt ccaacccctt
     8101 aatcttgctt acagatgcta ggtctgacaa cttgaatgtc tgaccattct ctatcttctt
     8161 aatagaaaaa gatgtattga gtgatttata aagattgctt tctactgttt tgttggactt
     8221 catcagagtc aaacaggctg aaattccggc caataagacc aataaaatca gaaataaaat
     8281 aaaacttctc agtcgctttc tgctgacata agcccaagat ctttggattg gattcatttg
     8341 tcacctccat atttgtaaga ctattataaa acccaaatat gaaatgttta tgaaatacga
     8401 aaaaaaaata tcgagtaggg gataatctct agcccctctc acaccacc
//
LOCUS       DAVLTT010000074         8411 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLTT010000074 DAVLTT010000000
VERSION     DAVLTT010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.074"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(<1..221)
                     /locus_tag="VYN15_001856"
     CDS             complement(<1..221)
                     /locus_tag="VYN15_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV1453136.1"
                     /translation="MKNNFLSRIQNKKANITIWGAGYIGLSTAYHFALVGFRVKIFDT
                     NHRLIQNLLEGNLPFKIDLDEEIFSKLIF"
     gene            complement(322..393)
                     /gene="shp3"
                     /locus_tag="VYN15_001857"
     CDS             complement(322..393)
                     /gene="shp3"
                     /locus_tag="VYN15_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HEV1453137.1"
                     /translation="MKKISKFLPILFLVMDIIIIVGG"
     gene            474..1325
                     /locus_tag="VYN15_001858"
     CDS             474..1325
                     /locus_tag="VYN15_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEV1453138.1"
                     /translation="MKSKLGVTLRKIRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTKTESFANLVQYIRKQYSSQNINNIQSLLSDS
                     SNYTLNSLEKTMVKSILHTMDSNVIPSDEELLQLTDYFFKVEKWGYYEIILLVNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKRIVTQLAINCLILSIDKKKFSNCSYLIDEIK
                     ELLDNELNFYEQTVFLYATGYFEFKRQLSSGIETMKQVIQVLDILGEDKLKLHYTSHF
                     DKLVNNK"
     gene            complement(1700..2863)
                     /gene="ltrA"
                     /locus_tag="VYN15_001859"
                     /pseudo
     CDS             complement(1700..2863)
                     /gene="ltrA"
                     /locus_tag="VYN15_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(3671..4349)
                     /locus_tag="VYN15_001860"
                     /pseudo
     CDS             complement(3671..4349)
                     /locus_tag="VYN15_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(4417..6240)
                     /locus_tag="VYN15_001861"
     CDS             complement(4417..6240)
                     /locus_tag="VYN15_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV1453139.1"
                     /translation="MVITKHFAVHGKCYRKKIIKYILNPEKTENLALVSHYGMRNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRHEENQRLIHAHHIIQSFSPEDHLTPKQINQ
                     IGYETMKELTGGKFRFIVATHVDKNHFHNHIIVNSVDNNSDKKLKWNYKVERNLRMIS
                     DRFSKIAGAKIIENRYSYHQYKVYRKTNHKYELKQRLYFLMENSTDFEDFKKNAPLLH
                     VKMDFSHKHATFFMTDSTMRQVVRGNKLNHKQAYTEEFFKNYFAKRKMEELMEFILPK
                     VDNLEDLIKKAKLFGLNINPKQKHVSFQFAGVEVKETELDKKNLYDVEFFKDYFEKRK
                     DLKAPEVQDLVQVYQEERFSKEKELPSEEKFWESYQEFRRNRDAIHEFEVELSLNQIE
                     KVVDDGIYIKVKFGIRQEGLIFLPNMELDMEEDKVKVFIRETSSYYVYYKDDAEKNCY
                     MKGRTLIRQFSSENQTIPFRRKTTVEMIKEKIEEVYTLLELDTDKHSYITIKDELVHE
                     LAASELRINAFQERVTTLNQVAEYLLASVENKQEMKMNLSKLNITDKIGIDVVEKELN
                     ELGIQIELESDRYENIVFKLNKFINRLSKKISKEEGIGFQK"
     gene            complement(6227..6592)
                     /locus_tag="VYN15_001862"
     CDS             complement(6227..6592)
                     /locus_tag="VYN15_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV1453140.1"
                     /translation="MENRYRTNLKKVFLSDSELGQLKHCIDQSGCQSFSEYARRTLLD
                     PGMNFITIDTTGYQDLVFELKRIGNNINQIARSVNQSQLISSEELQDLKKGIADLIRE
                     VEKEFSIQAKKLREFHGHH"
     gene            complement(6597..6953)
                     /locus_tag="VYN15_001863"
     CDS             complement(6597..6953)
                     /locus_tag="VYN15_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453141.1"
                     /translation="MPEQYRDIRKEVNLTANELEMIGVMMKNKGFEHFSSFARNKLLE
                     NELEMTAEKWFTFWRAQKLEQISRDVYEILILSRAEHQVTQEHVSILLTCVQELIQEI
                     GNSISLSQDFRKKYMR"
     gene            complement(7847..>8411)
                     /locus_tag="VYN15_001864"
     CDS             complement(7847..>8411)
                     /locus_tag="VYN15_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HEV1453142.1"
                     /translation="KNPFIDCTNSNFLQSMAQYYFLEDFSEYDVLNNLFPEYNDEFRK
                     ELLKKLKRLRQRPTQSLIEEIASYLDVSITNYEDKLESQILLEILSNLDNKKMFDTNL
                     MSNNLLMTTHASKGLAADTVVIFVEYLIDWRTGLKFEDHYVAITRAKSKVIIIDNRTI
                     YTSEINRLLSNNNGNFSFEDFIERRYI"
BASE COUNT         2565 a         1681 c         1221 g         2944 t
ORIGIN      
        1 ttaaatatta acttactaaa tatttcttca tctaaatcaa ttttaaatgg cagatttcct
       61 tcaagtaaat tctgtatcaa tctatgatta gtatcaaaaa ttttgacgcg gaaacctacc
      121 aatgcaaagt ggtaagctgt agatagacct atatatcctg caccccaaat tgtaatattt
      181 gccttcttat tttgaattct acttaggaaa ttatttttca tcgtatgtta aactttctac
      241 gttattttat tcataattta gtcataatca atagaattag tctttagata ctctaaagac
      301 ttaggtgtac acctaagcat tttatccacc aacaataatg ataatatcca ttaccaaaaa
      361 caaaatcggt aaaaattttg aaattttctt catactctga cttcctttca ttttttattt
      421 attgtacaat aaataagaaa taagttaatt tttgttagga aaatgggaaa actatgaaat
      481 caaaacttgg tgtcacactt agaaaaattc gtaagggcaa acaaattagt ctatgttctg
      541 tagctgatga gcatctttca aaatcgcaaa tctctcgttt tgaacgtggg gaatcagaaa
      601 tatcttgtat tcgactgatc aatattttag acaaattaca cattacgtta gatgagtttc
      661 ttattttaca cgatgaagac tataccaaaa ctgagtcttt tgctaactta gtacagtata
      721 tccgtaaaca atattcatca caaaacatca ataatataca atctctactt tcggattcct
      781 caaattacac cttaaattct ttggagaaaa caatggtaaa atccatttta cacacaatgg
      841 attcgaacgt cattccatca gatgaagagt tacttcaact aacagactat ttcttcaaag
      901 ttgaaaaatg gggttactat gaaatcattt tattagttaa ctgtgtacgc acaattaact
      961 acaactccta tttcctattg acaaaggaga tgttaaataa ttacatctac tcttctctaa
     1021 ataaaaccaa taaacgaatt gtcactcaac tcgcaataaa ttgtttgatt cttagcatcg
     1081 ataagaaaaa attttctaat tgctcctatt taattgatga gataaaggag ttgttagata
     1141 acgaattaaa tttctatgaa cagacagttt ttctctatgc cacgggttac tttgaattta
     1201 aacgtcaatt aagtagtggt attgaaacaa tgaaacaagt tatacaagtt ctcgatattt
     1261 taggagaaga caagttaaaa ttacactata ctagccattt tgataaactt gtaaacaata
     1321 aatgaaatga ttccttacca tctaacgttt tataatcaag agtctcaata aaaccttatc
     1381 aactccgatg aacttgtagt tttaactata gacagattga gtaggggata atctctagcc
     1441 cctctcacac caccgtacgt gccgttcggc atacggcggt tcaactaact tttaacgcat
     1501 gtcgttcaag gtaataatcc aaacacgaaa ccaatccacg tttttcaagg actggttttg
     1561 atatagcacg tttaagtacc gacttctgag ctactatagt ggattgaaac tagaatagtt
     1621 cacctctgct tctaaaacat tgttagaaat cgatttgact atcctgatcg atttgttcta
     1681 ttcttatttc attttactat aattgatagt ggtcgcccca gccagatacc ttatctgcta
     1741 tccatttagg aacccctaac ttaagcaatc cccataatcg tctcgatttc ttcttccatt
     1801 gcttccagat aatcactcgt aggcgagtat gcaaacgctc atctatgctg gtgactatac
     1861 ttttcatatt tcccaatgag aaatagttta tccatcctcg aatagacaaa ttcagttgct
     1921 caatacgtct tgttaggtct atactccatt tcctctgtgt tagtttcttc aatttaagct
     1981 taaatctcca aacactatct tgatgtggac gacttttcca accatctgat gatttccaga
     2041 acccgaaacc tagatatttc aactctcttg gtctggtaat cttagtcttg gtcatgttta
     2101 ctttcagacc tagccgtttc tcaataaaac gactgactga atacatcaca cgcttagcgg
     2161 ctgcctcgct tccgaccgta atcacacaat cgtctgcgta gcgaacaaat cgaagccctc
     2221 tcttttctaa ttccttgtcc aattcattaa gcatgatatt ggataagaga ggagataaat
     2281 ttcctccctg tggcgtgcca actagcgttt tataacgttg accgttaatg ataacacctg
     2341 aatgaagata tttacgaatc aaggattccg tatctccgtc ttcgataatg ttatgtacta
     2401 aggacatcaa tctatcttga ggaactgtat cgaaaaattt ctctaggtct atgtccacta
     2461 tccactcata gccgtcattt aagtactcta agagcttcat gatggctttt tcacatgacc
     2521 tatttggtct gaatccatag ctcgtatctg agaaatgggg ttcacaaata gggctaataa
     2581 cttgaacaat ggcctgttga atcattctat ccataactgt tggaattcct agttgacgga
     2641 tgcctccgtc tggtttaggt atctcaactt taagaactgg ttgaggctta tattttctct
     2701 gttttatcag ttccttagtc aagcgccagt tttgtctgag ataattatcc atctcttcga
     2761 tagtcattcc atcaatccca gctgagcctt tattggattt tacttgattg taggcttcca
     2821 gcatattttc gcgtgataat atcttatcta gcagttttga catgtgccta ttcctttctt
     2881 gttttggtgc ctgagggaca tcttatattg gtgaaccttc atctagtcat tacgtgtcaa
     2941 agtccagttc tatcagacca ctcattttac agacacaagt gaagtaggat tacttcaatc
     3001 tgtcgttttc tctttctagc gacagacctc aaacagtctc tccccagact gtttgagtat
     3061 tcaccccttc gctccacttc cattacggaa gtttcctcac tactatgggt tcggctgact
     3121 tctcatgatt cgttgttact acgctttcag cactcatgag acctcacggg ataagtcgta
     3181 catctttcct cgtttataca agatatgagg acgttaaaag gttacagtga aaataggaaa
     3241 tctgacgcag agtctttaga ctctaggaag atttatcttt ttcacataga ccttagtccg
     3301 aattcaatta ctctcgtgat ttacgcatat aggttacgac tacctttttg gactttagag
     3361 ttttaagccc ccttatccgc tgtatacgcc ttactatcac gttcctgttc gtagagcctc
     3421 gatttcgcta tcccttcctc tgacgattct tatttcctgc gtcagactta aaacggtcta
     3481 tccccagacc gttttaatcc gctacctcac gatagtcagg cttgggaatc gctattgggt
     3541 tcaccggtag cgggtgccca cggaggactt acacctcaga tgcacgacat gcccgtcgta
     3601 ccttaaaaag ccttggaaaa aactgtttcc aaggctttct ctatatttgt ccttattgac
     3661 caaaccagtt acattgcttt atcgtatctg tgattttagt aatagcctct tcagtattat
     3721 tctgcaacca tagatagcga caaacattat aattaaattt aatagaaagg tttaattctt
     3781 cgattgtgtt taacttgagt tgatttactt gatactctaa cttttctcta atttcattaa
     3841 aactctctaa atcttcaata tcataataaa aattgaatag agtatttgca acttgagggt
     3901 aggtcaagtc agttacactt aactgagata gtaccttctc caatattgcc acagcctcct
     3961 ctttttgccc atagaaataa aaatctataa gagattttat ccactccata taaaatttat
     4021 ttaccagaga caagcgatgt acctttacac tctctaattc atatatattt caaagattca
     4081 taatttcgat ttgtgataaa tgtctgggct aactttttaa actctgataa ctcatcaatc
     4141 tcttctacaa tctgctcatt aaaaaaataa tctacactaa cttttaactt cttagacaga
     4201 gcatataaaa agtctgctcc tggagtaaat tctccattct ctaatcgact aatctgtccc
     4261 tgtttacata tcccctcagt caattctcgc tgagacattt ttaattcttt tcgtctattt
     4321 tttaatctgg ttgctaatag tgtgcccaag tttgcatttt ccttttctat tcgatttcaa
     4381 aagatacaaa ttatatataa gcaatgacta gataggttat ttttgaaaac ctatcccttc
     4441 ttcttttgaa attttcttac tcaaacgatt gataaactta ttcaatttaa atacgatgtt
     4501 ctcatatcta tcgctctcta attctatttg gatacctaac tcattcaact ccttctcaac
     4561 aacatcaatg ccaattttat cagttatatt caactttgaa agattcattt tcatttcttg
     4621 cttattttca actgaagcca gtaaatattc tgctacttga tttaaggttg tcactcgttc
     4681 ttgaaaagca ttgattctca attcagaagc tgctaattca tgaactagtt catctttaat
     4741 tgtaatataa gagtgcttat ccgtatccag ctcaagtaaa gtatacactt cctcaatctt
     4801 ctcctttatc atctccacag ttgttttcct gcggaacgga attgtttgat tttcagagct
     4861 gaattggcga attaatgttc tacctttcat atagcaattt ttctcggcat catctttgta
     4921 atagacatag taggagctcg tttctctgat aaaaaccttc accttatcct cctccatatc
     4981 gagctccatg ttaggcaaaa agataagccc ttcctgacga ataccaaact tgaccttgat
     5041 gtaaatacca tcatccacta ctttttcaat ttgattgagt gacaactcta cctcaaattc
     5101 atgaatagca tctctatttc tcctgaactc ttgataggac tcccaaaact tctcctcgct
     5161 tgggagttct ttttcttttg agaatctttc ttcttgataa acttgaacta aatcctgaac
     5221 ttctggagct ttcaaatctt ttctcttctc aaaataatct ttgaaaaact ctacatcata
     5281 taagtttttc ttgtctagtt ctgtttcttt cacttctact cctgcaaatt gaaaagaaac
     5341 atgcttttgc ttaggattga tatttaatcc aaatagtttt gcttttttaa tcagatcttc
     5401 taagttatca accttgggta aaataaattc cataagctct tccattttcc tttttgcgaa
     5461 gtaattcttg aaaaattctt ctgtgtaagc ttgcttgtga ttgagtttat taccacgcac
     5521 cacttgtctc atagttgagt ccgtcataaa aaaggtagca tgcttgtgac tgaaatccat
     5581 cttcacatgt agtaatggag cgttcttttt gaaatcctca aaatcggtag aattttccat
     5641 caaaaaatag agtcgttgct taagttcata cttgtgattg gtcttacgat aaactttata
     5701 ctgatggtaa gaatagcgat tctcaataat ttttgcacct gcaattttag aaaatctatc
     5761 tgaaatcatg cgaagatttc gttcgacttt ataattccac tttagttttt tgtccgaatt
     5821 gttatcaacc gaattaacaa tgatatgatt atggaaatga tttttatcaa cgtgagtcgc
     5881 aacgataaaa cgaaatttac caccagttaa ctccttcatt gtctcatagc caatctgatt
     5941 gatttgttta ggagtgagat gatcttcggg tgaaaaggac tgaatgatat gatgagcatg
     6001 aattagtcgt tgattttcct catgcctgtc gtggcgaaaa tcgtaaagcg tatcattact
     6061 gataaaattt tcatgataca tctgcaccat ctcctcataa ctaggaaaat ccagaaaatt
     6121 cctcatgcca tagtgcgata ccaatgcaag attttcggtc ttctcaggat tgagaatata
     6181 cttgataatt tttttgcgat aacactttcc gtgaacggca aaatgcttag tgatgaccat
     6241 gaaactccct caacttttta gcttgaatac taaactcttt ctctacctct cttatcaagt
     6301 cagcgattcc ctttttcaag tcttgcaatt cttcacttga aatcaactga gattgattga
     6361 cacttcgggc aatctggttg atgttattac caatcctctt caactcaaat actaaatctt
     6421 gataaccagt tgtatcaatg gtgatgaaat tcataccagg gtcaagtaga gttcgtcgag
     6481 catattctga aaaagattga caaccgcttt ggtcgataca atgtttcaac tgacccaatt
     6541 cgctatcaga caggaaaact ttctttagat tggttcggta acgattttcc atgtgcctac
     6601 ctcatgtatt ttttacggaa gtcttgacta agagaaatgg aattccctat ttcttgaatc
     6661 aattcctgaa cgcaggttaa gagaatggat acgtgttctt gggtgacttg atgttctgcc
     6721 cttgataaga ttaaaatctc ataaacatca cgactgattt gttccaactt ttgagctcgc
     6781 cagaaggtga accacttttc agcagtcatt tctaactcgt tctccagtaa cttgtttctg
     6841 gcaaatgaag aaaagtgttc aaatccttta tttttcatca ttacgccaat catttctaat
     6901 tcatttgcgg tcaaattaac ctctttgcga atgtctctgt attgttctgg catactactt
     6961 cctcactttt atctattgtc ggataattcc cgaccccgtg tcaaccacgg gaaacttata
     7021 aaaacaaaat ctatcatctt gtaaggcttt gcgagctcag atattgtgtc cacaatatcc
     7081 caaaaatcat atcgccagct aatcaaaacc taccagtttt gacagctaac gataagataa
     7141 cttggtggct ccgcccccaa acccccagtg aagatttgag gttttatttt cttaagaatg
     7201 atataagaat agcagagaaa atttggaaaa gatatcacag gagaatgaga ggatgaaaaa
     7261 aagagagcaa atgctctcaa tgaactcata taaatatata tcaaaatact cttcaaaaac
     7321 ataaggttct aaagattatg tagaaaaagc tttagcaagt cttaaacact ctgttgctct
     7381 aacttatact ggtcgatgct aaaataattt aattccttga agtaattttc cagcttttaa
     7441 atgatactct tgatttttca tctcctctaa acgactatct acagctaagg caaatatatt
     7501 ccatattaca ttccatcttc gtatcttgtt cttgtcatat aatcttaaat gtcatagagc
     7561 atggatttca tattttgata attaggtatt cctaccaatg ctcgactagc tctatttatc
     7621 ccttcaacat aaccctttga gtcattcaat ataccaaaat tccagaacct tttagaatta
     7681 ttcggtgtct agttgtaacc gtaatactcg taaaatggct aatgtagtac aatcatcttc
     7741 attttttatt tttcaactcc tgcactatta aaatcaatgt gccaattaat tgcagaacct
     7801 aaaacacctg taatatcaaa ttgcaatcta tcttgattta gactagtcaa atatatcttc
     7861 tttctataaa atcttcaaaa gaaaaattcc cattgttgtt acttaataat ctattgattt
     7921 cactagtata aattgttcga ttatcaataa ttatgacttt tgattttgct ctagtaattg
     7981 caacataatg atcttcaaat ttcaatcctg tgcgccaatc aattagatat tctacaaaaa
     8041 ttactacagt gtctgcagcc aaaccttttg atgcatgagt agtcattaat aaattattac
     8101 tcattaaatt tgtatcaaac atttttttat tatccaaatt actcaaaatt tccaacagta
     8161 tttgactttc taacttatct tcataatttg taattgaaac atctaaatac gaagctattt
     8221 cctcaataag tgactgtgta ggtcgttgac gaagcctctt taattttttt aaaagttctt
     8281 tcctaaattc atcgttatat tcaggaaaaa gattattcaa tacatcatac tcagaaaagt
     8341 cttcaagaaa ataatattga gccatagatt gcaaaaaatt actgttagta caatctataa
     8401 atggattttt t
//
LOCUS       DAVLTT010000075         8392 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLTT010000075 DAVLTT010000000
VERSION     DAVLTT010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8392
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.075"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     misc_feature    78..213
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            252..752
                     /locus_tag="VYN15_001865"
     CDS             252..752
                     /locus_tag="VYN15_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV1453143.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNNFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            828..1196
                     /gene="rplL"
                     /locus_tag="VYN15_001866"
     CDS             828..1196
                     /gene="rplL"
                     /locus_tag="VYN15_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV1453144.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            1383..1553
                     /locus_tag="VYN15_001867"
     CDS             1383..1553
                     /locus_tag="VYN15_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453145.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            1553..1804
                     /locus_tag="VYN15_001868"
                     /pseudo
     CDS             1553..1804
                     /locus_tag="VYN15_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            1791..2138
                     /locus_tag="VYN15_001869"
                     /pseudo
     CDS             1791..2138
                     /locus_tag="VYN15_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2131..2511
                     /locus_tag="VYN15_001870"
     CDS             2131..2511
                     /locus_tag="VYN15_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453146.1"
                     /translation="MIDLYLSKNSRRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLKLTDFIEMILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            2524..2667
                     /locus_tag="VYN15_001871"
     CDS             2524..2667
                     /locus_tag="VYN15_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453147.1"
                     /translation="MAERFWKNLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            2760..3347
                     /locus_tag="VYN15_001872"
     CDS             2760..3347
                     /locus_tag="VYN15_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1453148.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            3549..3686
                     /locus_tag="VYN15_001873"
     CDS             3549..3686
                     /locus_tag="VYN15_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV1453149.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            3976..6470
                     /locus_tag="VYN15_001874"
                     /pseudo
     CDS             3976..6470
                     /locus_tag="VYN15_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808684.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
     gene            6503..>8392
                     /locus_tag="VYN15_001875"
     CDS             6503..>8392
                     /locus_tag="VYN15_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HEV1453150.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLM"
BASE COUNT         2823 a         1159 c         1714 g         2696 t
ORIGIN      
        1 aaaagaaaaa ttacgaaaaa ttttaaaaaa agtttgcaaa aatcttgcat tctttttttg
       61 actatgctat acttatatac ggtttaaaaa aactgcctaa gacagtaggg gagctcgact
      121 cataaatatc ctaccgagga caagacgtat catgtaaaaa gaagcgtatt gtactttcgt
      181 gtctaggttt gggcgcgttt ttctttttga aaaattcccc aagcaaaata attacggagg
      241 tgaacacact aatgagtgaa gcaattattg ctaaaaaagc ggaactagtt gacgtagtag
      301 ctgaaaaaat gaaagctgct gcatctatcg tcgttgtaga cgctcgtggt ttgacagttg
      361 agcaagatac agttcttcgt cgtgagcttc gtggaagcga agttgagtat aaagttatta
      421 aaaactcaat cttgcgtcgt gcagctgaaa aagctggtct tgaagatctt gcatctgtat
      481 ttgttggacc atctgcagta gcattttcta atgaagatgt tatcgcacca gcgaaaatct
      541 tgaacaactt ttctaaaaac gctgaagcac ttgaaattaa aggtggtgca atcgaaggcg
      601 ctgtcgcatc taaagaagag attcttgcac ttgcaactct tccaaaccgc gaaggacttc
      661 tttctatgct cctttctgta cttcaagcgc cagtgcgcaa cgttgctctt gcagtcaaag
      721 cggttgcaga aagcaaagaa gacgcggctt aatcttaagc tacacagcgt agcctagcta
      781 cgaaaaaaac tattataaaa tttaaaactt atttggagga aataacaatg gcattgaaca
      841 ttgaaaacat tattgctgaa attaaagaag cttcaatcct tgaattgaac gaccttgtaa
      901 aagctatcga agaagaattt ggtgtaactg cagctgctcc tgtagctgtt gctgcagctg
      961 atgctgctga tgctggtgct gctaaagatt cattcgacgt tgaattgaca tctgcaggcg
     1021 acaaaaaagt tggcgttatc aaagttgtac gtgaaatcac tggtcttggt cttaaagaag
     1081 ctaaagaact tgttgacggt gcaccagcac ttgttaaaga aggcgttgca actgcagaag
     1141 ctgaagaaat caaagctaaa ttggaagaag ctggagcttc agttactctt aaataataga
     1201 gtatcgcaat ttgattgcgg aatccctatt taccagtctt tgagagcgat aagcgattga
     1261 tagaaactga taaattgatt tggtttcctg ccaaaaattc tttggcagga tttttgtttt
     1321 aataaacttt cgggggtaga cactagattg tctacccctt tttttgtgtt tcggaggtaa
     1381 ttatgcaaaa ggaaggacag tcatcacgtc aattcgtgaa gagtcatctc atgactatca
     1441 tgggagttga tattgtaaaa gcaactcagt tagttgatga aatggaacaa gtaggtttaa
     1501 tccgatttga tgaatttgga aatgttggaa ttttagtctt ggagggacaa taatgaagcg
     1561 tattaccgct aatcaatatc agacatcaga gcgttattat aagctcccca aacttttatt
     1621 tgagagtgaa cggtataaga atatgaaact ggaggttaag gtggtttact cagttttaaa
     1681 agatcggttg gagttgtctt tgagcaaagg ttggattgat gaggatgggg ctatttattt
     1741 gatttattcc aattcaaatt tgatggcact tttaggctgt tcaaagtcaa aattactctc
     1801 catgtgagtt tgaagtaaca tttttagatg attaccataa aaaacacaac tacccactat
     1861 tttacgaatc ctatcttcaa aacgttatgg aattccttga aagtcaagac ataaagaatg
     1921 gggttgatgc ctttgtagat gatcatcaaa atctcgtttt tgttttatat ggacaaggct
     1981 atcgagccga gggaaaagag ggaatactta caacccaagt aactgtaaaa gcttatgatg
     2041 aagacaagaa accgattaac ttcgcaaatt tattagattc cttaatcgtc tcagaatatc
     2101 aaatggaacc gaatctttgg gaggtctcct atgattgatc tctatctaag taaaaatagc
     2161 cgaagaaatc aacttctttt agacttcttc caaaactatg gcatcgaggt atcttgtcat
     2221 tcagtttctg aaatgacaaa ggacaaatta attgagatga tgagctattc ttcagattgt
     2281 tttgagtttt tatctccaaa tttattacgt tttaagaatc gagataacct aaaattaaca
     2341 gatttcatcg aaatgatatt aaaaaatcct gaactaacca tcagacttcc tcttgcggtt
     2401 tcaaataagc gagtttatcc aagtctgaat ttggaagagg ctagagctct attgccaaga
     2461 gatacgaaac aattgattta catggcgcaa acacattatt tatctaacta aaggagaagc
     2521 aatatggctg aacgattttg gaagaacttg tccattattt tggctgaaag aaatatcagc
     2581 tggattgagt taaccagaaa aatgtttgcg ggagagtttc actatccaag tgaattgaat
     2641 cgtttgtatc aaaagattcg ccactagaag atggaacaac gaatgcctca aagttcatgg
     2701 gtagaaagga ttgtgcaggt attagattta gattatgaag atttatttcg gaggtaacta
     2761 tgaaaagaat aattccagtt tatatattcc aacaagtaaa tgtcctattg gtatctctat
     2821 acttattgaa atttctttgt atcggtgagt taaccatact acagattctc tatggttcgt
     2881 cactcatttc ttttttatgg atgtatggcc aacgcaaaca agcgcataag gtcaatatga
     2941 aatctaggat gaaatggctt ggtgttgaat ttgttagcct actgattata agtctatgtt
     3001 ttagtctgat tcatgctcaa ggaagcacga atcaagcaaa cttaattggc cttcaacatc
     3061 aaattccttg gttttcattt ttattgttct taatcaatgc gagtatggtt gaagaatttc
     3121 tgtatcgaga aattttatgg aatttggtca gaaaattaga tatcagagtt gctttgacaa
     3181 gtgttttatt tgccttagca catcatacag gaaccattct agcttggtgt ttgtatgttt
     3241 cacttgggat gtttttaggt atggtgcgct ataaatctga cttatggggc agtatgggac
     3301 tacatttggt gtggaaccta ctagtttata gtttgctgct tttttaaaat aggtgacctg
     3361 atttttaggt aacttctaaa actaacttcc agttttggga gagagatgga agttactttg
     3421 aaaagttacg gaaacattat tttctatgtg acaacattgt ataattgctt gcattttact
     3481 ggtggagaga gtataatgag ggtggataaa gtacttaatc ccaaaaattt aaataggagg
     3541 agctagctat ggcagaagaa gtattaaatc ttcaattagt atctgttcaa gttgacgaaa
     3601 cagatgaagt tgatggaatg cgatttagta cattcagtac aaatcgttgc ggtaactgga
     3661 gtgcttttag ttgggaaaat tgttaattca tttaaattgt aaactttaga gattctctgg
     3721 agttatggat gtcgttccaa tatgtgcacg ttggaatgtt agtgcttata tggggagaat
     3781 ccaaaggatt ctcccttttt atttaaataa gtctgtctag ctatagatat attaagtttg
     3841 ataaaatttc ttggagattt tgttatggat tataatttca atttggagca tcctttcttt
     3901 ttcactaata atgattatag tacagatact agcataaagt accaagtaag tctgcctttt
     3961 aattggcacg aagtaatgaa taatgatgag tgggtttatc aataccctat tggaaaattt
     4021 gttgaaagac aagggtggaa aatacacatt agttcagagt ataacagttc acatgaattg
     4081 ttacaagatg tagcaaaaat ttgccatgaa atgcgaattc catttaaaca tcttagtaca
     4141 gaagacaaat ttatcatgcg aaacgggaaa ttggttagtc gaggattttc tggtaaattt
     4201 attacatgtt atccaaatca aaatgaatta gagtcggttt tgcaaaggtt agaaagtgcc
     4261 ttaaagcaat ataatgggcc atatatttta agcgataaac gttgggatga agcaccaata
     4321 tatctgaggt atggtgtgtt taggccgtca agggatgatg aaaagaaggt tgctattgat
     4381 gaattaattg ttggcgatga agttgttaaa gatgaacgtt taccagtatt taaaattcca
     4441 aaaggtatag tgccccctga ctttttgaat aaatggcttg acaagaaaga taaaaaacag
     4501 ggagactttc cctttattat agataatgca attagatttt caaacagtgg tgggatatat
     4561 aatgctaggc taaaagaaga tgggaaaaaa ataattttaa aagaggctag accgtataca
     4621 ggtctaggat ttgatggtac ttattcttca gagaaattag cttcggagtg caaagcacta
     4681 aaaattctaa atgaatggag tgagacgcct aaaatatact ggcacggtaa gatctgggag
     4741 cacaccttct taggaattga acatatgaag ggcgttccac taaatagatg ggttaccaat
     4801 aattttcctt tatatgaagt tgttgataag accaaagatt atctattgag agtttcaaag
     4861 atagtagaaa aactcatcga tttaacgaat aagtttcatt ctgaaaatgt atatcatcaa
     4921 gatttacatt taggaaatat cttggttaag gatgaagatg agattagtat aatagactgg
     4981 gaacaggctg tcttttcaaa tgatgaaaaa gttgtacata aagttgcagc ccctggtttt
     5041 agagcatggc gagaaacact tcccagtgag atagattggt atggtattag acaaatagct
     5101 cattatttat acatgccact agtaactaca tcggatttga catacaacta tgtaagtcaa
     5161 accaggatag aaggaaaaaa actatttgag tctttgggtt atacaagaga acatatagat
     5221 tatgtagaaa gtttattgtc atatctagat tctaaatgtc cacagattga gaatatttcc
     5281 aggaaaaaag ttttaaaacc catgcatgag attagaacta tcgagagtga gcaagatata
     5341 caagatttta ttataaaatt attgagaggg tttacgctaa cttatggaca gtggcgtaaa
     5401 gaatttcaat caagattctt cccagttcat tattatggtc tgaattttaa tcaaggaatt
     5461 gcgttttcag atttagctat cctttggagt tatcaacaac tagctaagaa agtaaaaaat
     5521 ttcaagtttg atgactatta tgagattcga acacaggtta ttaatgaggc agtaaataat
     5581 tttaagaaat cgtccctttc tggtcttttg atggtaaaat tggtacaatc tggctcattt
     5641 atgaatttgg ggagatagat cgggcagttg aactttttac aactcatttt atagagatat
     5701 ttgagaattc acaaaataaa aatttatata gtgggcaggc tggaatttta ctggttggac
     5761 tgtattttct tagtaaaggg gaaattgata ataaactagg agaagaaata ctaattaggc
     5821 ttagagaata tactttaaat tatatagaaa atccagaaac tttttgtaaa gttggcgcta
     5881 gtgatgttca gagtaatgat ccttatgaga attttggtgg attactatat ggtcacgcag
     5941 gggtagcttg gctcttcggt gaagcttata aattaactgg tgaaagtatc tataaaaatg
     6001 gtctagaatt ggctgtagat aaagaattag ttgcttataa agtagatagt aataattcat
     6061 tgcagtacag ccaaggtaga ttactaccat atctagcaac tggaagtgct ggcctgcttt
     6121 tacttattaa tagaaataaa gaaatcttgt caagcaaata cttaaaatat ttaacttctt
     6181 tagagagggc aactgatgta gttttttgtg tattaccagg tttatttaac ggattttgtg
     6241 gtcttgaagt tgctaataat atatatagtg atatcgatga taacttttca ggacaaaaga
     6301 aattaattga acaactttat agatatttgt gtgtaattga agaaggattt gttattgcgg
     6361 gagataatgg tttaaagata acaacagata ttgcttcggg atttgcgggt gttgcaattg
     6421 gattggtatc aataatggat aataaattga cgattcttcc tcaaatataa tatttagata
     6481 ccattattaa ggggtcatac ttgtgaatca gagtaatgaa atatttttaa atacaataca
     6541 ggaaaaaaca cactataaga ggtctatctc ttcatcattt caggaattaa aaaaatggaa
     6601 ttctttgata tttaggagag ggcgatattg gtaccaattt gataattgga gtatacccaa
     6661 tactggtgta ataaaggaat ggtatgtcga agataatgac tggattccta aggttagttc
     6721 ttccagttta gacaattcaa attcacttaa aattgtcttt gatgtggaaa aatatacttt
     6781 gccagatgat agtatcttac aggatgttag gatttcatct gatgagagtt atatagtttt
     6841 ggttgtatcc tcactgcgta gcactaattt aattggaata aaaaaatata ctatggaaga
     6901 gttatttatc attgaagata tttcagtaga aagttcgttc tatttgggta aattcggtgt
     6961 tatgtatact cgctccaaag agtacgggag gccaagtaag ttattctata aatcttttga
     7021 tagctttaca gaagaggaac tgtttgaaga aaacgaatgc tcttttcgat taaaaatagt
     7081 ccacattgat agcaataatt gttttgtaaa gtcagtagac tttcagaaag gcaggatttt
     7141 tctatacagt ttcgaccgga cgggttttgt tagacactct tacacagaaa cggtagcccc
     7201 aacacctaga gatatcgctc tatttagtac agaaaaagca cagtactttc ttgggctctc
     7261 ttcaactgaa gaaaagaaag atcaactaat tctaagggaa acttcttcgg gagacagagt
     7321 ttctattact ataccatatc aagatagggc tagaagagtt cactgtatag gacgttatat
     7381 ccttttagac tgttcaaacg cagcgaattc cgtcttttat cttgctacat ttaaaaataa
     7441 tagtttgagg gagttgagtg ttaataagat aacatttgat gaaaagacaa cactttatga
     7501 aaattcattt tctgatcgtg ttcttctgtt tttagagagg agaacttttt acgaaaaaat
     7561 acttagtttt gatttaatag aaaatacatt aaaaactgaa tttgaaagac ccatcataaa
     7621 atcgaataat actaaatatt tttctaaggt gatttggact aaaaaagaca gttatgatgt
     7681 aagcataccg atttctttat tttggaaaag tgaagatacg gatgagctcc caagaagaaa
     7741 aaaatgtatt ctaagtgtct atggggctta tggtaagaat gataattctg atttagatga
     7801 aattatgtta tctataatag atgcaggttt tatttatgct atagttcatg taagaggtgg
     7861 aggctatttg ggtggtgaat ggtatcgctc aggaaaggcg ttaaacaaat ggaattctat
     7921 cagagatttt attgagggag taaattattt aagggaaaat gatgtaattg acagtaagcg
     7981 attaggttta ataacttcta gtgcaggtgg aataattgct ggtgcggtgt tgaacgagga
     8041 aaaaaattta ttgcaaagca ttctcttatt ttcgccattt ataaatcctt atgatacact
     8101 tcagaatcca aatgatcctc tttctaagac cgaaatagca gagtggggag atattagaga
     8161 ccctgaagta aaggcttata taaagtcata ttcgcctatg caaaatattg aaaaggcacg
     8221 agactcaaat actgttatag ttaatatttt gggtgagaaa gacccatata ttaataataa
     8281 cgaagtgata gagtggtcaa agaaattaaa ttctattgga gttaaaagtt tgttgtattt
     8341 aaacaaagca gctggtcatg gaggttttac tccatcagat gttctcttaa tg
//
LOCUS       DAVLTT010000076         8362 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLTT010000076 DAVLTT010000000
VERSION     DAVLTT010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8362
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.076"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(160..363)
                     /locus_tag="VYN15_001876"
     CDS             complement(160..363)
                     /locus_tag="VYN15_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1453151.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(356..1438)
                     /locus_tag="VYN15_001877"
     CDS             complement(356..1438)
                     /locus_tag="VYN15_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1453152.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1564..2346)
                     /locus_tag="VYN15_001878"
     CDS             complement(1564..2346)
                     /locus_tag="VYN15_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV1453153.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2346..3689)
                     /locus_tag="VYN15_001879"
     CDS             complement(2346..3689)
                     /locus_tag="VYN15_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV1453154.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRYGEIYTTYKMILDAIRKVPT
                     ATVLLNGDSPLFYKPAIPNPVEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3788..5104)
                     /locus_tag="VYN15_001880"
     CDS             complement(3788..5104)
                     /locus_tag="VYN15_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV1453155.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5298..6524
                     /locus_tag="VYN15_001881"
     CDS             5298..6524
                     /locus_tag="VYN15_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV1453156.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            6723..8297
                     /locus_tag="VYN15_001882"
     CDS             6723..8297
                     /locus_tag="VYN15_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1453157.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
BASE COUNT         2382 a         1629 c         1865 g         2486 t
ORIGIN      
        1 tgtgcaatac agaactaaat ccttcggata aattaattgt ctaacttttg gggggcagta
       61 catattcaac acctgatact atgcgtttta ttgtgggaag attttcctca ttttctagtg
      121 aaattgaact ttttctaaca tcttttgata gatgacttct taatcaatta tcatttccat
      181 tgttgtttct tggggtttca tcccttgtct ttgataaaag cggagagcac cctcgttatc
      241 attccagaca cttagggtta gattattgca gccaatttct ttagcataat agcagaaaaa
      301 tgacaataaa atagccccta gatattttga aaggaaagca taggggctat atagtttaat
      361 caaaataaag caaatctttg ctggtgcttg taaagaggtc gaagccatcc ttggtaacaa
      421 caccgcagtc ttcaatacga acaccgactt taccagggat atagatacct ggttcaacag
      481 agaagcacat gccttcttcg atgaccatgt cgtttccttc catgatagat gggaattcat
      541 ggacatccat accgatacca tgcccgagac ggtggttgaa gtactcacca taaccagctt
      601 tttcgatgac ctcacgggca gcgcggtcca cttcatgagc agtcacacct ggcttgataa
      661 agtcaagagc agcttgttgg gcttcaagag tcaagttgta aatatctttc ttgaattggt
      721 ctggtttgcc gacagcgact gtacgagtca tatctgacgc atagccattg accagaacac
      781 ccaggtcaaa gaggagaaga gcatcatttt caaccttatt agctgctgga atgccgtgtg
      841 gattcgcagc attatcacca gtcaagacca tggtatcaaa gctcatttcg taaccttcac
      901 gtttcatggc aaagtcaatt tgtgcgatga tatctgtctc agtcttatca agagaaatat
      961 tgtcaaaacc aacatgaaca gccttgtcag cataaagacc tgcaaccatc attttttgca
     1021 cttcatcagc tgatttgatg aggcgcatgc gttggatacg aggagtgagg ttgtcaaact
     1081 cagcagtctc aaaaactgtt ttcaaaccat ggtatttggt caagatgaga ttgtcaaact
     1141 caacagcgac acgtttgaag tcaagttgtg gaagagcatg tttgattttt tgccatggat
     1201 tttcagaatc gacataaccc actactggga aggaaacggt gctacttgca cgttctactt
     1261 caagagctgg gacaaagagg agaggttcct gatccgctag gacaaagagg aacatttggc
     1321 gttcatgggg atcactgtaa aaaccagtga ggtaattgat tgtgacgggg tcagatacga
     1381 cagcgacgtc tagtttttct gattcaagat atgttaggat ttgttgtaat ttagacatat
     1441 gctaccttct ttctacccct ctattttggc aaaaaatgag agaaaatgca agggagaagg
     1501 gtaaaagaaa agacaaaaaa ctccgacaag ataacggagt tctttgatat cattttcctt
     1561 tgtttaagaa aagtcagcct tgcttttgac gtcactgtac tcttcagcga tttcttggct
     1621 gaggatatcc tcataggcag ggagttggat atcctgacca tatttcttct tgagggcagt
     1681 agtaactagg cgataagcca gattggcatt acgagagagg ataggcccgt ggaagtagga
     1741 accaaagaca ttcttataat gaaccccttc accgaccttt tcttcgttgt ttccatttcc
     1801 atagacaacc tgtcccagcg gtttttggtc atcagagagg aaggtacggc cttggtgatt
     1861 ttcaaatcca tagtaggttt catcgaaatc ttcattgtga atcttgatgt caccgataaa
     1921 acggttattg gtctggttga gcgtgtagtg tcccatgacc cctagccctt cgatacgttt
     1981 tcctgaagct tcaacataat attgacccaa tagttggaaa ccaccgcaga tagccagaac
     2041 tacaccgtcg ttttggatgt agttgtcaat gctctctttt ttagcaggta ggtcgtctgc
     2101 aatgatactt tgttcaaagt cttgaccacc accgaaaaag gcgatgtcgt agtgattttc
     2161 atcaaagtca tcatggagag aaacgatgtc aacggtcaca tgggctccca gtttttcagc
     2221 cacatacttg agcatgagga tgtttccatt gtccccgtag gtattcatga gatttccgta
     2281 gaggtgggca atgttgagct gataggggta attgccatct tttgaggaaa gtgaagtata
     2341 aaccattagt tcatctcctt tctaacaatc tgacgactag ccagcagttc acgaaattcc
     2401 agcatggcag tataagttgc cagaatatag gcatgcttgc agtcttgatt ctcaatggtc
     2461 ttgagaactt gctccagatt actcgtttca gtgattttct cagctggata gccagtcact
     2521 cggaggcgac gagcgatttc agaatgacga acaccgccag cgttgatttc aggaatgtcc
     2581 atgtcagtga tttgttcaaa gtctgcatcc cagatccagc tagtgtcaat tccatctgca
     2641 tagttggcat taaggaggac agataggcta aatggataag gtgctagttt gatcatttcg
     2701 atagcttggg ttgcaccgac tggattttta atcaagacaa gggtacattc cttgtcacca
     2761 atatgaaagg tttcttggcg tccaaagaca gcacggctct tgtcaaatcc ctgtttgatg
     2821 agttgggaat ctgcgccgag gaaacgggcg atggccacag cagctagggc gttatagata
     2881 ttatagagcc cgccgatttg gataccgtat tcttggccgt ctatgacaaa gcgagagcga
     2941 ttgttggtca actcaaccag ttttgtcaaa cgatagtcga gatcaggacg tttacatcca
     3001 caaccttcac agatataggc acccaagttt gcataggtat tatgctcata tttgaggatg
     3061 ccttggcagt caggacagag gattccttcg gtattatagt gagccagctg ggctggacct
     3121 ttctccaagt caaaaccaaa atactctaca ggatttggaa tagctggctt gtagaaaagt
     3181 ggactgtctc cattaaggag aacagtggca gtaggcacct tacgaatggc atccaaaatc
     3241 atcttgtaag ttgtgtaaat ctcaccatag cggtccatct ggtcacggaa aatattagta
     3301 ataacaaata agcttggctg gatatagtca cagatacgag atagactggc ctcgtcgatt
     3361 tctaggacgg caatattttt cccagtttta gaagatttgg ctgttaagaa ggttgtcgca
     3421 attcctgtaa tcatgttggc accgcttggg ttggtcagaa cttgaccata aacttctttt
     3481 aaaataccga cagtgagggc agttgtcagg gtttttccat ttgttccagt gacaacgaca
     3541 atctcgtagt tcttagctag gttttgtaaa atatctttat caaattgaag ggcgacttta
     3601 cctgggagcg tacttccacg tccaagacgg cttaaaacga agtgggaaga acgcccagca
     3661 agaaggccca aagtagtttt taagttcatg tttctattat atcacaaaag agggaaaaga
     3721 cagatttggt gtttcgtaga agtaaaaaca gcccaaagag ggctgtcagt taagatgaga
     3781 tttcaactta aatcgcaaac aagtcattca agttctcagc caaggttggg tgagtgaaaa
     3841 tttgttttgt gaagtaagtg taaggaatct tgttgtccat agcaacagta atgatgttga
     3901 tgatttcttg agaaccttct gagaagatgc ttgctccaag aatttctttt gtttcagtat
     3961 taacaacagc tttgaaagct ccgcgaaggt ctccatttac gtgaccacga ggcatggctg
     4021 caacagggat ttctttcact gcgtatggaa gtttcaaatc agctgcttgg ctttcagtca
     4081 aaccaacttg tgaaagtgca ggtgtgatga acatagtatt tggcacattg agacggtcct
     4141 caagtgtgta gctgccatct ccagcaaggt agctgtaaac aacacggaag tcatcaagtg
     4201 aaatgtaagt aaattgaaga ccaccgttga catctccaac tgcaaagaca ccaggaacgt
     4261 ttgtttgaca gtgtttatct actttaatag cgccacgttc agttagttca atatctgtat
     4321 tttcaagttg aagtggttct acatttggtt tgcgtccagt tgcgtagaga agggcgtcga
     4381 aacggtaagt ttcgtcttca gttacgacaa gcacttggtc accgtcgttt ttaatttcag
     4441 tagtatggat attttgaagc aattcaatac cgtcttcttc caggtattgt ttagcaagag
     4501 ctgcgatgga aggttctgca cgaggtagga atgtatccaa ggcatctagg actgtaacct
     4561 tgcttcctag tttattgtaa aggccagcaa attcaagacc gatatttccg ccaccaagga
     4621 ctccaagttt ttcaggcaat ttatccaagc tttggatacc tgttgagtca aagacgtttt
     4681 tgcttgtagc aagtccaggg attggcaaga cgtttgaaac agcaccagtg ttgatgacga
     4741 tagtttcagc agtcaattct tgtttttcat caccagcttg gatttcgatg actttatttg
     4801 aaaggaagtg agcttcagca tcaaagatat tgacgccagt accagcaaca gtcgtgtagt
     4861 ttttaccgtt gaggcgacca gtgatcgtgt ttttggtagc aatgacttct tcaaaagata
     4921 agtctttctc agcagcaacc agcaaagttt tagttgggat acaaccgatg ttgatacaag
     4981 ttccaccgta catagctttg ctacgttcaa cgagggcaac ttttttgcca gctgaagcca
     5041 atttacctgc tagtgtttta ccagctttac caaatccgat aacgattaaa tcataagtta
     5101 acatttagag ttcctcctat tcgcatttca ttctagcaca agaaaaaaac ttttgcacaa
     5161 ttctgctacg gaaaagacag aaaaagataa aaacgctttc cagacaaaaa actagtaatt
     5221 ttttgacaag cttgataaac taaaatccta tctattttta tataagatag aataaatgtt
     5281 cgaaaatagg aggttttatg aaatcgaatc gttatattat tgcctttgct ggggtcattt
     5341 tacacttaat gctgggttcg acttatgctt ggagtgttta tcgtaaccct attattgaaa
     5401 aaacgggatg ggatcaggct tctgttgcct ttgcctttag tctagcaatc ttttgtttgg
     5461 gcttatcggc tgcatttatg gggcgtttgg tagaaaaatt tggtccgaga gtcatgggga
     5521 gtctatctgc ttttctatac gcaggtggaa atatcttaac aggatttgca atagaccgtc
     5581 aggagctgtg gttgttgtat ctcgcttatg gcattttagg tgggcttggt ttgggagcag
     5641 gctatattac ccctgtgtcg acgattataa aatggtttcc tgataaacgt ggtctcgcaa
     5701 caggtttagc gattatgggg tttggttttg cttctttatt gactagtccc atagcgcaac
     5761 acctcatcgc aggggtaggg attgtagaaa ctttttatat tttaggagca agttacttta
     5821 ttatcatgct cctagcttca caattcatta agcgtccaaa tgagcaagag cttgcaattt
     5881 tatcttcttc agggaaagaa aaaacagcct ctttgacgca aggaatggct gcaaatcagg
     5941 ctctaaaaag caatcggttt tatatgcttt ggattatttt ctttatcaac atagcttgtg
     6001 gtttaggctt aatttcagcg gcatcgccaa tggcacagga gatggctggc ttgtctacaa
     6061 gtcatgcagc agtaatggtg ggtgttttgg ggattttcaa tggatttggt cgcttgctct
     6121 gggcgagttt gtctgactat atcggtcgcc ctctaacctt tagtatatta ctgcttgtca
     6181 atcttttctt ttctctctca ctttggctct ttacagattc cgttttattt gtagttgcta
     6241 tgtctatttt gatgacttgc tatggagctg gtttttcttt gattccagct tatctcagtg
     6301 atatttttgg aaccaaggaa ttggccgctc tgcatggtta tattttaaca gcttgggcaa
     6361 tggctggttt agcgggacct attttattag cagagactta taaaatggct cattcgtaca
     6421 cacaaacctt gttcgttttt ctcattttat acagtatcgc cttggctttg tcttattatc
     6481 taggtcgttc aatcaaaaaa gaaagtcaaa aaccgcttac atgattttct gtagaaatgg
     6541 ggctatcttt tgctctggtc ttgtgttata ctagataggt tgcaaagaaa acagtacttt
     6601 tcttttgtgg aaaagaagca acacgatttt atatctagtt atatgaaaat acgtcataaa
     6661 aagaaaagta taaactaagc cctatagggt ggcttcgcac cacctttaga aagaagaata
     6721 acgtgaaatt taatgaatta aacttgtctg ctgatttgct ggcagaaatt gaaaaagctg
     6781 gttttgtaga agctagtcct atccaagaac aaactattcc tttggccctt gaaggcaagg
     6841 atgttatcgg tcaagctcag actggtacag gaaaaactgc agcctttggc ttgcctaccc
     6901 ttgaaaaaat ccgtacagaa gaagcgacta tccaagcttt ggtcatcgct ccaactcgtg
     6961 aactagctgt ccaaagtcaa gaagaactct tccgctttgg tcgtagtaag ggagtcaaag
     7021 tccgttcagt atatggcgga tcaagcattg aaaaacaaat taaggctctt aaatctggtg
     7081 cccatatcgt ggtgggaact ccaggtcgcc tcttggactt gattaaacgc aaggccttga
     7141 aattacaaga cattgaaacc cttatccttg acgaagcgga tgaaatgctt aacatgggct
     7201 tccttgaaga catcgaagcc attatttccc gtgtacctga aaaccgtcaa actttgcttt
     7261 tctcagcaac tatgccagat gccatcaaac gtatcggtgt tcagtttatg aaagcccctg
     7321 agcatgtcaa gattgcggct aaggaattga caacagaatt ggttgaccag tactatatcc
     7381 gtgttaagga acaagaaaaa tttgacacca tgactcgtct catggatgtg gcacaaccag
     7441 aactcgctat tgtatttggt cgtaccaaac gccgtgtgga tgaattgact cgtggtttga
     7501 aaattcgtgg cttccgtgca gaaggaattc atggcgacct agaccaaaac aaacgtcttc
     7561 gtgtccttcg tgactttaaa aatggcaatc ttgatgtttt ggttgcgaca gacgttgcag
     7621 cgcgtggttt ggatatttca ggtgtgaccc atgtctacaa ctacgatatt ccacaagatc
     7681 ctgagagtta tgttcaccgt atcggtcgta caggtcgtgc tggtaagtca ggtcaatcta
     7741 ttacttttgt tgctccaaac gaaatgggtt accttcaaat cattgaaaac ttgactaaga
     7801 aacgcatgaa aggtctcaaa cctgcaagtg tagaagaatc cttccaatca aaaaaacagg
     7861 tagctctcaa gaaaatcgaa cgtgattttg cagatgaaac cattcgtgcc aactttgaga
     7921 aatttggtaa ggatgctcgc aaattggctg ctgagtttac tccagaagaa ttggcaatgt
     7981 atatcttgag tctgacagtc caagacccag atagccttcc agaagtggag attgcacgtg
     8041 aaaaaccact accgtttaaa ccatcaggta atggtttcgg tggtaaagct aagggaggtc
     8101 gtggaggccg tcgtggggac gaccgtcgag agcgtgatcg tcgtggcaat ggtcgccgtg
     8161 atgagttcaa aaaaggaagt cgtggcaacg atcgttttga taaggaaaaa cgttaccgta
     8221 aggataataa aaaaccacgc aatactttaa gcgaaaagca aacaggcttt gttattcgta
     8281 acaaaggtga taaataagaa aaagcggttc aaaatgaatc gcttttttat ataaggagac
     8341 cgaatgtgaa aaagacaaat aa
//
LOCUS       DAVLTT010000077         7614 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLTT010000077 DAVLTT010000000
VERSION     DAVLTT010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.077"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(82..714)
                     /locus_tag="VYN15_001883"
     CDS             complement(82..714)
                     /locus_tag="VYN15_001883"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV1453158.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVDAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSDLIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(748..1449)
                     /gene="pyrF"
                     /locus_tag="VYN15_001884"
     CDS             complement(748..1449)
                     /gene="pyrF"
                     /locus_tag="VYN15_001884"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV1453159.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIYYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHTIKDEWTQDWN"
     gene            complement(1682..2860)
                     /gene="divIB"
                     /locus_tag="VYN15_001885"
     CDS             complement(1682..2860)
                     /gene="divIB"
                     /locus_tag="VYN15_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV1453160.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEIEESES
                     KEKEEQDKKLAKKAIKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEESNRNQTTQRSSRR
                     "
     gene            complement(2870..3928)
                     /locus_tag="VYN15_001886"
     CDS             complement(2870..3928)
                     /locus_tag="VYN15_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV1453161.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(3932..5284)
                     /locus_tag="VYN15_001887"
     CDS             complement(3932..5284)
                     /locus_tag="VYN15_001887"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV1453162.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(5388..6029)
                     /locus_tag="VYN15_001888"
     CDS             complement(5388..6029)
                     /locus_tag="VYN15_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1453163.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(6031..7449)
                     /locus_tag="VYN15_001889"
                     /pseudo
     CDS             complement(6031..7449)
                     /locus_tag="VYN15_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
BASE COUNT         2148 a         1725 c         1414 g         2327 t
ORIGIN      
        1 cattttattt aaaatattgt catattttaa ataaaatggt aaaagaggct cggtagcctc
       61 gtctctcttt atcttactga cctaaccttc ttgccaattt tcttggtctt ctttaaagcg
      121 ttttagaaga tcaaggccct ctggcgtgat gtaaccttct tcttgggcta gatggataag
      181 atcgctatag tttgaaagcg tcacaagttt aacaccagca tctgcaaagt tcttatctgc
      241 ttttggcaat tggtagctga aaatcgctac aactccaagc acatctgctc cttctcgctt
      301 ggctgctgct acagcttcaa gaactgaacc acccgttgaa ataaggtctt caaccactac
      361 cattttttga ccttgagcta cgcgaccttc gatttgatta ccagctccgt ggtcttttgg
      421 tttgctacgg atgtaggcaa aaggcaagtc catcttatca gcaataatgg ctccgtgtgg
      481 aatccctgct gttgcagttc ctgcaatcac ttctacttca ggaaaggctt ctttgatagc
      541 atccacaaaa ccattttcaa ttagggtacg agtttctgga taggctagtg tcacacgatt
      601 atcagtgtaa atcggtgact tgataccaga tgcccaagtg aagggttcct ctggtttgag
      661 gtaaacggct tggattttca agaggtggct agcgatatct ttagcaagtg tcatggtatt
      721 ctccttttat ttttctaatc tagttcttta attccagtcc tgtgtccatt catccttgat
      781 ggtatgataa gctgcaacag gatcctcagc ttgggtaatg ggacgtccca ctacgatata
      841 gtcactgccg atttgatagg catcagcagg tgtcatgact cgtttttgat ctccaactgc
      901 agcaccagct ggacgaatcc ctggtgtcag acagataaaa tctggattgg tagcctgctt
      961 gatgacttgt acttcctgag ccgagcaaac aacaccatcc aagccagctt cagctgtctt
     1021 cttggcatag taaatcacag actcttgcag actggtttgg atattttgaa actcctgcat
     1081 ctgggcttct gacgttgatg tgagctgcgt tacagcgatc aatttagctt gactcccaag
     1141 accttcacgc gccgccttca tcatctctac accaccagcc gcatgaacat tggtcatatc
     1201 cacaccaagc tgagatagga tcttcattgc tgacttgact gtattaggaa tgtcatgaag
     1261 tttgagatcc aaaaagacac tatgacccaa accttttaag taggacacaa tctcaggccc
     1321 cgctgcgtaa taaagctcca tccctacctt gagataaagg ctttcttctg ctgggaaaag
     1381 agctaaaaat tccttgaccg cctcaaaact aggaaaatca agagcaatga ttggacgatg
     1441 ttctcgcata ggtttctcct tttaccttta ctagtgagag agtctggcca acagaagcca
     1501 cgaaaaaagg aacctgccaa cagcaaggtt ccacgaaaaa tgggtagtct ccaccctttc
     1561 accgtctaac cttagctgcc tctctggact gctttaaagg ttttttacta ttctattatt
     1621 tctactagca cttgtcaagt aaaaacttag tcactaaaga actataagag aaaaggtaaa
     1681 cctagcgacg cgatgaacgc tgggtcgttt ggtttcgatt gctctcttcc tcttgttttt
     1741 tctcagcttc cttggcctct tgtttggctt tttcctcagc ttccataatt aatttatccg
     1801 ccacagtgta actgtaaatt ccagcttcca tgtcaatcac actcggttct gacaattgtg
     1861 gcttaatctt actgtaatat ggcagtttct tactcatttc agatagagga accaagactt
     1921 cgtccgaatc attcatggtc aatcgaatta aatcggatgt caccttgctt ggggctaatt
     1981 ccaccttttg gatagccgcc ttgagttctg ggctaatttg agcaagttct gagacaaaaa
     2041 ccttgatttg ttcactatca ttaaagagaa ctgataaata agtttctggt aaactgttca
     2101 gactcacaga actagtctca agctgaccac tggaaagaat aggataatga ttttcaccag
     2161 aaatatagta ggccacaata tcatattcct tgaccttaat agtgaactta gttggaaatt
     2221 gatagacaag ttgagctgat tcaacccaat agttagactt aatctgcttt tcatattttg
     2281 ccttgtctag cagaaggtta atcgtataat ccgaatcctg aatgcctgaa gcctgtcgaa
     2341 tatcatcagc tgtagtttgc accgttccct caacacgaat atctttcatg gtcgcataag
     2401 gactgagcaa gtaggcagag acaatcaata aaagcagact tggaaataaa atcgtgaagg
     2461 ctcgcaagat atggatacca ggaatctttg ctttggctgg tttttccttt atagcctttt
     2521 tagcaagctt tttatcctgt tcctccttct ctttagactc tgattcttct atctcttctt
     2581 tttctttgtc agcctctgag gatgccactt tttcttcaga ctcttcctta gctgattctg
     2641 aatcttcctg gtctgtttca ctctcctggt cctgtttatc ctctgacttc tcagattctt
     2701 ctcccattcg agcttgtctt tccttttcct tctcctcagc tagagccgcc tcttcttcag
     2761 ccttcttttt tagatattct tggtttcgtt tctgccattc tgataactct ttcaattctt
     2821 cgagggtttc tttgtcctca tttttcttat cttttgacat ttactttcct tatgataaat
     2881 cttttttcaa caattgataa aaatctgcta gagatttcaa ttccttagaa gctttcatct
     2941 tagcttggta atcttccttg tgacttagta agtgagaaag cttctcttcc aaactatcca
     3001 aggtcaaatc gctttcttga aggtcttctg catagccttt ttttacaaag taagctgcat
     3061 tttcaatctg gtcaccacga ctagcttcac gaccaagcgg cacaatgaca tgcaattttg
     3121 ctatcgccaa gagctcaaaa atcgtattgg caccacctcg tgtcacaaca atatcagcca
     3181 attccatcaa gggttgatag agatcggtca catagtcaac acgaaaaaga ttttgcctca
     3241 actcattcag actagaatct ccagttagat tgataatatt gtagcgctct gttagttctt
     3301 tcttatggtc tgtcaccaat tggttaaaga cacgagcgcc tgcagaaccg ccgacaaaca
     3361 atacagttgg caatttggga ttaaagtggg tttgaatatc caccaattca tctggttctg
     3421 gagtgttttt gtccgaaacc ttggtcaccg ctcccacatg ctcgacctta gccaaactcg
     3481 aagcttgttc aaaggttgaa tacatcttag tcgcaaattt ataggcgatt ttattggcca
     3541 agcccataga caggtcagat tcgtgaataa agacaggcac tcctgacaca cgcgcagcga
     3601 taacaggcgg tactgagaca aagcccccct ttgaaaaaag ggtctgtgga cgcagtcgca
     3661 acatgataaa gagcgattgg acgattcccc agccaacttt gaagacgtcc agcatatttt
     3721 gccaagagaa atagcgacgc aatttcccag tcgcaataga atggaaggtg acatccaaac
     3781 ctgacttaag gatttcttgg tgttcgatac cacgcttgtc cccgatatag tggacttccc
     3841 aaccatcttc gatgaacttg ggcattaaca aaagattgag ggtaacgtgt ccaaccgtcc
     3901 ccccacctgt aaagacaatt tttttcatat tttattcttt taactccgct actgtgtcga
     3961 taaagaggtc gccacgtact tcaaagttag catacatatc ccagctggca ttggcaggac
     4021 taagaagaac cacatctcct tgagtcgcaa gttcataggc cttacgggtc gcatctgcaa
     4081 tatctgtcgc ctccacataa gcgacaccag ccttgtctgc tgcccgtttg acacgttctg
     4141 cagattgacc caggatgacc atcttcttga gtccagtaat gtctggcacc aattcgtcaa
     4201 actcattgcc acggtccaaa ccacctgcaa tcaagacgac cttgctgttg tcaaatcctg
     4261 ataaggcttt ttgagtagcc aagatattag ttgatttact gtcgttatag aatttaacac
     4321 ccttgatgtc atccacaaac tggagacggt gtttgacacc accgaaggct gaaagagttt
     4381 ccttgatggt ttgattgtcc acatcacgaa gcttggctac agcaatagtc gcaagggcat
     4441 tttccacatt gtggctacct ggaacaccga tttcattcgc tgccatgact acttcaccac
     4501 ggaagtagag ttgaccatct tccagataag ctccatcaac cttttcaagt gttgaaaatg
     4561 gtacaacagt ggcttctgtc ttggaagtca agtcttttgc caagtcttga ttaaagttca
     4621 agacaaggaa atcagctgct gtcatcttgt tctggatatt ccacttggct gctacatatt
     4681 ccgaaaatga cccatggtag tcgatatgag ttggcatgag gttggtaata accgcaatct
     4741 ctggatggaa ttcttgaaca cccatgagtt ggaaagaaga aagttccata acaagcgtgt
     4801 ccttatctga tgctatttga gcaacctgac tagctggata gccgatattc cctgataaaa
     4861 gaccatgttg cccagcagca gtcaaaactt ccccaatcat agtcgttgtg gttgtcttac
     4921 cgttcgatcc tgtgatacca ataatcggtg cttctgaaat caaataagcc aattccacct
     4981 cagtcaagac tggaattccc ttggccaaag ccttttcaat catgggattg ttgtagggga
     5041 tacctggatt tttcaccata agggcaaact cttcatccaa gagttccaaa ggatggccac
     5101 ctgtaatgac cttgatccct tcttccagca aactttgggc agctggattg tcctcgaaag
     5161 gtttcccatc atttactgtc acaatggcac ctagcttgtc caacaaacga gctgcagatt
     5221 caccagactt ggccaagcct aaaacaagga ctttcttatt tttaaattga tctattactt
     5281 tcatgtctcg aactccattt ctactcctac tattttacca tttttatgga aataaaaaag
     5341 ccacaaagtg tgtttgtgac tctttcttct gactgaatct taccatatca tctatgtgat
     5401 aaatcggtaa ctcgaatgac ctgatccact tgctcccaaa tcagaggatt atgggtcgca
     5461 ataataatgg tccgattcgg attttttaaa gattctagga tggaaagtaa ttcctcagag
     5521 tttttggggt ctaaggaagc ggttggttca tctgcgagga tcaaaggtgg atcctttaaa
     5581 attatcttcg ctagtgcaac acgttgtgct tctcctcctg ataactcaaa tataggttgc
     5641 ttcaaatcca aataagagag gtttacacgg tttagagctt gtttcatcaa agagattttc
     5701 tctttttcct tcaacttttt accaactaaa cccagattga gattctcttt gacggtttgg
     5761 ctttcaatta agccaaaatc ttgaaataag tatcctaagt aatctctaaa gaaaacagaa
     5821 ggcttaatgt ccttaagaga agtgccatca tatatgattt gccctttgtc atatggctct
     5881 aatcgtccaa tcatattcaa gagtgttgtc ttaccacagc cacttgtacc gattaaggca
     5941 taaattttcc caccttcaaa atgaagattc gtatctgaaa atagctgacg gcttccaaat
     6001 tttttagata tattctttag ttcaatcatc ctattttcct ttcataattg tcatagaaac
     6061 acgagattct ttctgcgctt gacggtaaag cgtcaaaact gcactaacta gaaagaccaa
     6121 taaagtgagc aagccaatca ccaagtctcg actgcttaaa ataaagagac tagcaccaaa
     6181 tacaaaactg gcaaattggc taaccatata ctgagcatgt gtttcaaaaa atcgtaaacc
     6241 tgaaattcgt ttaatcaaga tatctcggcg gaattgctcg aaatatagaa gattgacaga
     6301 ataaaagagt aacaaggaac tggctattcc aacaatagct cctaagatta aagttgctgt
     6361 ttcagtttga acttcattat aacgagttag ataaacactt cttccttctt taagatagga
     6421 tacttgctca taaattccag ctttcttcaa gagttctagc ccactctcat atcctttgat
     6481 aaagagttgt tttccagcat tgatagacca actagataag gatataaaac tatcacctgt
     6541 agaagtcggc gtgaatacaa ctaaaatcgg atcagtcaaa tactgagtag atacgggatt
     6601 ctcaccgtta ttataaacaa accgcttttc tcccattgaa agataactaa cgtgcgcttt
     6661 catctcataa tccaaaggag cacttgcctc ctcaccagat tttccataat aactcaatct
     6721 ttcttcaaaa actttcttaa gttctgcttc tcgagagcgc aaatgttctg ggagcaagag
     6781 gataaactca cctttttgga gatgggctaa cttctgtttg gtctcagcat ctaccacgac
     6841 cttttccttg tccaaataac tgggactaac atagagcgta ttagcatctg gactataggt
     6901 atccagtgtc tctccctgtt cattttttcc ttgtggattg gcaaaatgga gcagattatc
     6961 ctttacataa agagcttgtt cttcttcgat tgcttccttg gcaaaggcat accacttgct
     7021 ctgattttct gtatcttttc ctctatcacc taagccaaag gaaatctggt aatagtctgc
     7081 tctgtcctgc catgcttgtt ttgaaatttc aagttctttc aatcgttggt aagacgtcaa
     7141 acctgtctta acagcgtagc ctactgtaaa aacagctact aactgacaca atagggttaa
     7201 agccatcaag cgtttaaggg gtaatcttcc cttaataacg ggaactaatg ctttgtaact
     7261 caaactcatt aggtaaagga gcattagtaa aattgaaatc gccaataaaa acaacagata
     7321 gaaactaatc ccaaaaccat aggtggctaa caagatagga taaaacaaac cttgactaaa
     7381 aagaacgact cccccaccta ggaaggaaag gagggctgat agaaggagcc acttgatatc
     7441 agtagataaa ccccaattat tcaccccaaa tctaaaaacc atccagaatc cttgccttag
     7501 cttagatcct ggatggtttc ttttttcacc caatgggtgt tttttactag acaaaaaaga
     7561 gtttcccctt tatggtataa gtgtagaaaa aaacacaaaa agaaaggaaa ctca
//
LOCUS       DAVLTT010000078         7458 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLTT010000078 DAVLTT010000000
VERSION     DAVLTT010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7458
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.078"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(175..1521)
                     /gene="celB"
                     /locus_tag="VYN15_001890"
     CDS             complement(175..1521)
                     /gene="celB"
                     /locus_tag="VYN15_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEV1453164.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            complement(1601..2107)
                     /locus_tag="VYN15_001891"
     CDS             complement(1601..2107)
                     /locus_tag="VYN15_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453165.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LSQFISPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLALSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            complement(2138..2452)
                     /locus_tag="VYN15_001892"
     CDS             complement(2138..2452)
                     /locus_tag="VYN15_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEV1453166.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            complement(2462..4441)
                     /locus_tag="VYN15_001893"
     CDS             complement(2462..4441)
                     /locus_tag="VYN15_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1453167.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVEGLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            complement(4559..4873)
                     /locus_tag="VYN15_001894"
     CDS             complement(4559..4873)
                     /locus_tag="VYN15_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEV1453168.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            complement(5003..5242)
                     /locus_tag="VYN15_001895"
     CDS             complement(5003..5242)
                     /locus_tag="VYN15_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEV1453169.1"
                     /translation="MIGSIAAILTTFAFLPQVFRIVKTKDTGSIALGMYVMKVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            complement(5294..6730)
                     /locus_tag="VYN15_001896"
     CDS             complement(5294..6730)
                     /locus_tag="VYN15_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1453170.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            complement(6920..7258)
                     /locus_tag="VYN15_001897"
     CDS             complement(6920..7258)
                     /locus_tag="VYN15_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEV1453171.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVKEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
BASE COUNT         2526 a         1472 c          987 g         2473 t
ORIGIN      
        1 ttccctgttt atcaactatt cgaactactt tctattttgc ttcataccct acatagcaaa
       61 aaaataaaat gaaaaagcag agaagaatat cttaaaaaga tctcttcact gctaatgtta
      121 acactcatta tttaaactat atggattcta tcatcgagta tactttttta cttattagat
      181 accttgctct tctttcacca atttttgatc atatacacgg atgaatggaa gatagactag
      241 gaatgctgca aatgcacata ctagagcaac taatacagct cgaagatctg ctgtccctaa
      301 gaaagctcca atccctactg gagttggcca tggaacctgt gcgataattg gcttaataaa
      361 gtttagagaa ttcgctacgt aataaatagt agcagtaacc attggtgcta aaataaatgg
      421 tatagccaag gctggattat agataatagg taatccaaaa attaatggtt cattaatatt
      481 aaataaggct ggaactacag atgctcgtcc tattgcttta agctgttcag atttagaggc
      541 aaaagcaata tataaacata gtcctaaagt tgcaccagaa ccacctgcaa ttacaaacat
      601 attagaaaat tcacctgcaa cagcgaagtg cccgccagca gcattttcag ccatgttagc
      661 aagagcaatt ggactaacaa atgcaaaaac aatgttcgca ccgtggatac ctacaatcca
      721 aagtagttga gtcaatagat aaataatcat taaaccaatc cacgaattag tcagattgga
      781 tacaaaacca aatggaattg caatgacttt aaaaatatct gttcccattg ctacaagaag
      841 accgttgata aagataacaa caaatgcaac aacaaatccc ggaaccaaag cggtaaatcc
      901 acgagaaact ccttctggaa cagcttcagg cattttaata acccaattat gtttaacaca
      961 catacgataa ataagaacag tcacaattgc cataatgatt gcggtaaaaa tccctgttgt
     1021 cccaaaacgt gcgactccat ttcccattgc ccatccatct gcaattactg caccttcttt
     1081 tagacttgtc acagtcttca tcattccacc atcaaaaatg atttgcggta ctgtcatgac
     1141 aaaagccatc aaggcaagca aggcaccatt aagaggattc atattgagtt cttcttcctc
     1201 tgcataaatt tttgtcaatt catatgcaag tgatagaacg aaataaagag atagagaacc
     1261 catagtcgca tagtttgcaa ccatgtaaag tgatgtgaat ttatcaaatg aagcagagaa
     1321 aatatctgcc acaattggcc aaaatgagaa agcttgtggc aaaatactga ataccaaaaa
     1381 cattgatcct acaatagtaa atggtacagc agccatacct gcagccgtga tagcacgcac
     1441 tactttaaac tgagcaagtt tgcccattgg tcccataaca tggttttcaa gaaaaccaaa
     1501 caacccgttt tgttgatcca taaatagacc tccttaataa aacataataa tttttacttt
     1561 ctaaagactg gtttcaaata caaattatac tagatcagga ttataaacta agtgagttct
     1621 tttccaattg gacaaattgt tgataagcct tatctgttcg tttataaatt tttttaattc
     1681 ttctaatgtc taacaaactc agagctaaac ctaatagaag aactacaaaa acaaataaac
     1741 gtgctacttg gttattttca aaaatcggaa aaagattctt aaaccaactt gtccaagtta
     1801 aaacaagtaa tcctattgaa ataagcattt gtattctaac aaacattagt gttattccca
     1861 acttttcttt cctatttcca tagagtttaa attgttcaac agttgctaaa atagaaaata
     1921 ctatgagcat aatggggaaa ataataatag gcgagggact aataaactga ctcaaaagcc
     1981 aataaatatt cccaaaaaag aagagtgcta ttgaataacg tagaagaaga tatcgattaa
     2041 aaaaagtatt agttagagcc atctctcgac gttgttgttc aatcttttgt cgttcttttt
     2101 tatccatatc atttcctcct tatataacaa cacatattta gttaactttc ttataaagag
     2161 ctaacatttc ctttgctact tctaataatg tcatagtggt cattaaatga tcttgagcat
     2221 gtaccatgat aatttcaatt ttaatttcca ctccacttgc gtattcttgc aagagtttgg
     2281 tttgtgcatg atgcgcttca agaattatct catttgattg atttaattta ctttctgcat
     2341 catcaaaact accttctctc atttttgcaa atgcttcatg tatttctgac cttgcatttc
     2401 ccgaatgcag gataatttca aatgctgcaa cctgcagttc ctcttgattc atatgaacct
     2461 cctattttat cttctcaaat atgttaataa aatcttcaaa gttattgcaa gatattagct
     2521 gattttgcaa ttcatcattc tctgtcagag agactatctt tttagtcaca gttgccaaac
     2581 cttcgttccc atatattgat ggagatagaa gaaatactag ctggacatgt gaactttgat
     2641 tatcccagag tagcgaatct ttacaaattg caaccgaaac ctttccctct gtaccaaagg
     2701 gctgaatagg atgcggaact gcaatttttt cagaaaaaac aactgaactt aattcttcgc
     2761 gctgtttaat tccataaagt aaagattgtt caaactcatt tgattcacca acagataaac
     2821 cctcaaccat cttttcaagt aaatttacct tgtctgattc agtacatatt aaaaaatttt
     2881 ctttactaaa atactgtcta aagccgttgt tttcaaattt gttaatcttt gatgattgta
     2941 cataactaga aacttgcatc tgatccatag cttttctaat catttccatc tcatcacttt
     3001 taagaaacac actaacttta aaaactggga tttgaaaata tagatttgat aaatcaacag
     3061 ctgacactat aaaatctatt cctttaagtt tttcttgatt caattcatag tagcctatta
     3121 catcaacaac ttctactcgc ttcccaaact ccgtttccaa acgatttctt aacatttggg
     3181 ctgcaccaaa tcctgttgca caaatagcaa gaatattaaa cttagtactc tctttgctac
     3241 gttccatagc agctaaaaag tgaagactta catatgctac ttcatcatct gatattgtcc
     3301 actccaagaa cttgtccata tttgcaagaa tttctctagt cataaagaat atatcactat
     3361 aattctgttt aatttcatct accaaagggt tatttaaggt aatccggctt tctaaacgta
     3421 cttgtagtgt cattagatga gttatcaatc cttcaattag ttggaaatct gaagaaaagt
     3481 tatacatatc atctaatcct aaattctgaa atgttttaaa taaagatttt tttaaaactt
     3541 cttcagaaat attcttctga tttttttgac attgttgact cttagctaac aaatgcaaag
     3601 taatgtagtc tatttcctga actggaaatt cctgatttgt tacttctctt actttagaaa
     3661 gaattctttg ggcaaccttt ctctctattg catcatcagt catctgacag tctatatttt
     3721 ttatttcaaa tccggatttt aaacgaatca cagacaatgc tatgtgaact actaaattct
     3781 gtagtacaaa atcagatagt tttaggttgg cctcttggca ttcatccaaa acaattctag
     3841 caaattcttc taatggaaca gtttgatcaa aaaagttaaa ttttacatag caatgtattg
     3901 ttttaaaaaa ttgattctct aggaaataat ttatgataaa acgtcgttta tcacgttcct
     3961 cgcctgagac ataaactcct ttattcgccc tactctcaat ggacaaatta tactctgata
     4021 acatcactcg tatctttctg aaatcatgag ataatgttga acggctaacg taaagttcat
     4081 cagctaaatc atcaaaaaga actggaactt gctcaaataa taatttattt aagataaata
     4141 ctaaacgatc atcacctttt gaaaccgcag ttttcgtata gtcttcttcc agttcataag
     4201 tttgtctaaa ctcctggtaa gcgccttgat tctcaaaaaa tatttgatac ccttgacctt
     4261 gttttgaaat caaccggact ccttgaataa tcattgtctt ctcaattaat ttcagtacat
     4321 tacggacagt tctatctgaa caggataaat attctgccag ttctttgctt gtaacaaaac
     4381 gttccttatt ttttattaaa aattgaagga tatctttctc tttaatgttt aacacattca
     4441 ttccctccta aaacgtatgt tttcatatat tgaagcatat tatacactta aatcagttta
     4501 tatcaaactc aaaacaattt atcttaacct aaatatttat tgacatttca tgtgttcatc
     4561 aaatattctc aagaatcaaa ttagccattt tttcaattcc cattggaata ggaatatagg
     4621 cttgaggagg tatttgtaca actggttttc ctgctttaga accagcctct tcaaattgct
     4681 taaagtacat ttttgtttga gggctgacaa gatacaaatc aaaagctgct gctgcgatag
     4741 ctttccctcc ttcagtagca ctaatagcat caactacaat atctttccct tttcctttta
     4801 gaaactctgt tgttttctgt gccataagtg atgaagacat tcctgctgca caaataatta
     4861 aagcttttgc cataatattt tctccttttc ttaaatccaa tcaaagctgt gctaagttgg
     4921 cttatttgtt atctattttt attataaaat aaagcgtttc caatgacaat tccctcattt
     4981 tcctaaatga tatggaaaaa aattatttat acttcaattt ataaaataaa attattcctg
     5041 agagtagaaa tgaaacacta tttgctaaaa tcaaaggcaa gtctcctata cgaataccat
     5101 gagcaagcca caatgcaata ccaataactt tcataacata catacctaga gcaatagatc
     5161 ctgtgtcctt tgtcttaact atacgaaaaa cttgtggtaa aaatgcaaat gttgttaaaa
     5221 ttgctgcaat acttccaatc atatgtcatc ccaatatgct aaacaaactg agaataatct
     5281 cagtttgttt atactattct actgattcac cgttagatga aataacttcc ttataccagc
     5341 caaaagattt tttcggggaa cgattataac ttcccttccc attgtcatct ttatctacat
     5401 aaataaaacc ataacgtttc cgcatttcac cggtaccagc tgaaaccaaa tcaatacatc
     5461 cccatggagt ataacccatt aaatcaacac catcttcaac tacagccttt ttcatttcac
     5521 gaatatgggc acctagatat tcaattctat aatcatcatg taccatacca tctgctgcaa
     5581 cttgatctat agctccaaaa ccattttcaa caataaagag tggtaagtga tagtggtctg
     5641 taaaccaatt taacgcataa cgtaaacctt ctggatcaat ttgccactcc cattcagaag
     5701 ccttaacata attatttttc actaaatctt ctgtttcaag ataatcaaaa taaggattat
     5761 tttcacgatg agagtctata gcaaaggaca tatagtaact gaaaccaatg taatctacag
     5821 tcccaccaag taaatcttct ttatcctggt cagtaaaatc aactgaaata ccttttcgtt
     5881 cccaatactt gaaaatatgc tcaggatatt tacctaaaac atgcacatca gcaaaataat
     5941 aacgcttctg catagctttc attgccatta agatatcctt aggattgcaa gtaactggat
     6001 aaattggaca catcgcaatc atacaaccta tttgaaaatc tggattaatc tcatgaccaa
     6061 tttttacagc tcgtgcagaa gcaactaatt cgtaatgtgc tgcttgatac ataattgctt
     6121 ctctattatc accttcctca tatacaatac ctgagttagt aaatggtgca aaatcttcct
     6181 gataattcgc ttgattattg atttcattga aagtcatcca atatttaacc ttatctttgt
     6241 aacgtttaaa tacgacttct gcaaaacgag caaagaaatc aatcaatttc ctatttttcc
     6301 aaccaccata ttcggtcact aagtgataag gcatttcaaa atgagataga gtgatgacag
     6361 gttcaatacc attctttaag cattcatcaa aaagattatc ataaaactgt aatccttctt
     6421 cattcggctc taactcatca ccttttggaa agatacgtgt ccatgcaata gaggtacgga
     6481 agcacttgaa tcccatttca gcaaaaagtg ctatgtcttc tttataacga tgataaaaat
     6541 ctatcgcctc atgatttgga taatatttac cctctaaaac tcccaaagta atttcacgag
     6601 ctactccatg acgaccagca gtcataacat cagcaacact aattcccttg ccaccttctt
     6661 gccatccacc ttcaagttga tgagcagcaa cagcaccacc ccataaaaat ccatctttaa
     6721 aagtagtcat cttttttcct cctgactttg atactcttat tataaacctt aaaccaaaag
     6781 atgaaaacgc attctttttc cttattgtta aggaaagaag taatttttaa tggaaataga
     6841 acaatatctt cttgtattct cgtaatgata tctttacgat tttcaatact ttcaaactac
     6901 aaaaactctc acaataattc taattccctg tgtctataaa cgacttatcg ctttctggca
     6961 tcccagaatc atcttctata taacgttcaa cttgcatctg caagtgatat ttttttctta
     7021 aatctaagat tttctgcatt gtctttgatt gataatgttt atctaaagtt tcttgattta
     7081 tccactgatc aataaggaga atagttccct ctttttcaat tggtaaaaaa tattcgtatt
     7141 tcaagttacc tttttgattt ctaatttctt taacaaggcc actatcaagc atttctcttg
     7201 caaactttat tgcactatct ccatcacctt tataatatac atgaatagtc aatgtcatct
     7261 tatatcctcc aaaatcatcc ttcaatttta aaaaaacaag tttagatgag gatctaaact
     7321 tgttttttat gaactaatta tctaacgttt cgccattact ttcaatcact tctttatacc
     7381 aataaaatga ttttttctta tagcgattta tagtcaattg aaacaagagc aggacaaaag
     7441 agcctcataa aaggtatt
//
LOCUS       DAVLTT010000079         6849 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVLTT010000079 DAVLTT010000000
VERSION     DAVLTT010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6849
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.079"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..79
                     /locus_tag="VYN15_001898"
     CDS             <1..79
                     /locus_tag="VYN15_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEV1453172.1"
                     /translation="QVDKSQFACEIAIKVWRNSLKFSII"
     gene            109..3459
                     /locus_tag="VYN15_001899"
     CDS             109..3459
                     /locus_tag="VYN15_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1453173.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(3963..4433)
                     /locus_tag="VYN15_001900"
     CDS             complement(3963..4433)
                     /locus_tag="VYN15_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1453174.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4450..6723)
                     /locus_tag="VYN15_001901"
     CDS             complement(4450..6723)
                     /locus_tag="VYN15_001901"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV1453175.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHINKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         2098 a         1156 c         1480 g         2115 t
ORIGIN      
        1 ccaggtcgac aaatcacaat ttgcttgtga gatagctata aaagtgtgga gaaatagctt
       61 gaaatttagt ataatatagc taaactattt gtttaaagtg agaaaaaaat gggaaatttt
      121 agctttcttt taaaaaatga cgaatatgaa tctttttcaa aaccttgcat tgaagctgaa
      181 aatatgattg ctacatcaac tgtggctact gcctttatgg cgcgtcgtgc tttggagcag
      241 gctgtccatt ggatatatag tcacgattca tatttagaag ctccctatcg tgctactcta
      301 tcttctttag tatgggatga tgattttagg gatatcgtag attctgaact ccacaagcag
      361 atagttctgt tgattcggtg gggaaaccat gctgctcatg gtggtgaaat taaggaacga
      421 gaagcgattt tagctttaca tcatttgtat cagtttgtta attttatcga ttattgttac
      481 agcaatgaat ttgtggagcg ttattttgat gagaagtgct taccactttc agcaaacatc
      541 aaataccgag aaactccaca atctatgata aagttacaag acagtttacc agaactgcct
      601 gattttcatg aacagatggc tgctcagtcc gtagaagttc aagagactta tactgaaaaa
      661 cgtgagactg cagcgcaacg gcaagatgtg cctttccata ttgaacaatt atctgaggca
      721 gagacaagaa agctctttat tgatatcgat ctccgtttag caggatggat atttgaagaa
      781 aactgtcgtg ttgagatagc cgttgatggt ctcaagcacg gttcaggaat tggttactgt
      841 gactacgtac tttatggtaa aaatgggaaa attttagcga ttgtggaggc taaaaaagcc
      901 tctgtcaatc cagaagtagg ggaagtacag gtcaaagaat atgctgaagc tttggagaaa
      961 catatcggct atcagccaat ttgctttatt acaaatgggt tgaagcacta tatacttgat
     1021 ggtccgaacc gccgccagat tgcaggcttt tactctcaag aagaattgca attagtgatg
     1081 gatagacgtc atcttcaaaa accgcttgag gatatttcta gtaaaattag ggacgatatt
     1141 tccgggcgtc actaccaaaa acatgccatt gcaagcgttt gtgaagcttt ctctaatcat
     1201 cgtagacagg cacttttggt tatggcaact ggggcgggga aaactcgtac agcagtttct
     1261 ctagttgata tcttatcacg tcataactgg gtaaaaaacg ttctcttctt agccgataga
     1321 acttccttgg ttaagcaagc ctatgattcg tttagaaaat tactcccaga tctttccgtt
     1381 tgtaacttct tagaagataa agaaggagct caatcaagtc gtatggtctt ttcaacttat
     1441 ccgaccatga ttggagcgat tagtggtcaa gaagaagtaa atcaacgccc ttttactgtt
     1501 gggcattttg accttatcat aattgacgaa tctcaccgtt ctatttatca gaaatacaag
     1561 tccatttttg attattttga tgcaagaatt gtaggcttaa cagctactcc gcgtcaagat
     1621 ttagataaaa acacctatgg attctttaat ttggagaatg gggttccaac atatgcatat
     1681 gatttggaag aggctgttaa agacggatat ttagtagcct atcattctat cgaaaccaaa
     1741 ctgaaactac ctacggatgg tctacattat gatgatttgt ccgaagaaga aaaggaacat
     1801 tttgatagca aatttgaaga cgatagctgt gaaaaagata ttgatgggag tgtgtttaat
     1861 tcctttattt tcaataaaag tacagtagaa attgttttaa atgaactcat gacaagagga
     1921 attcagacag cctcgggtga tgaaattggt aaaactatta tttttgctaa aaatcatgac
     1981 catgcggaat atatcagagg tatttttaac aaccgctatc ctgaaaaagg gagcgactat
     2041 gctcaggtga ttgattatag tattaagcat tatcagacct tgattgatga ttttaaaatt
     2101 aaggagaagt atcctcaaat tgcgatttct gtcgatatgt tagatacagg tattgatgta
     2161 ccagaggttg ttaatttagt cttcttcaag aaagtacgct ctaaaactaa gttttggcag
     2221 atgattggtc gaggaacccg tctatgtaaa gatttatttg gacctgagca ggataaggaa
     2281 aacttcttgg tatttgatta tggggataat tttgattatt ttcgtgcaga tccaagagat
     2341 ggagagggtc gtcacattgt ttcgttgact cagcgtttat ttaatatcaa agtggacttg
     2401 attcgagaac ttcagggact ccaataccaa gaagatcagt ttgcgagagc ataccgtcag
     2461 cagcttgtct cggaacttca aggtcgtata gagagcttaa atgagttgga cttcagggtt
     2521 cgtatggttt tagatacagt ttatagctat aggaaattgg aaagttggca gaatctaact
     2581 gctgttacaa gtgaaaccat tcaaaaaaat ctctctccgc ttttatttga tgaagataaa
     2641 gaagatgaga tggcgaggag atttgatttg tggttgcttc atattcagtt ggggcaactg
     2701 acagctaaat cttccactgt tcatatttcc caagtgatga agacggctag agctctttct
     2761 gctattggca atatcccgca ggtttttgag caggctgaaa ttatcaggaa agtacaggag
     2821 cctgaatttt ggaaagaagt taacttgtct gatttggaaa aaattcgtct tgctattcga
     2881 gatttattac agtttttgga taaaacagac cgtaaaccct actatgttaa ctttgaagat
     2941 cgtatactct ccactgttca cgagaccaca gcatttttgc aggtcaacga tcttcggtct
     3001 tacaatgaaa aagttgagca ttatttgaaa actcatctgg atgaggagtc catttctaag
     3061 ctataccata ataaaaagtt gacatctgat gatatgcttg cacttgaaaa attgctctgg
     3121 gaaaaattag gtagtaaagc agactaccaa agtcattatg aaaataaggc aattccgaga
     3181 ttggttcgtg agattattgg cttagataga gagtctgcca atcgtatttt ttctaaattt
     3241 ttgtcggatg agaatcttaa tgccaggcag atttcatttg taaaattgat tgtagactac
     3301 attgtagaaa atggtttttt agagacgaaa gtgttaacgc aagagccgtt taaatcttat
     3361 ggttctgttc aactactctt ccaacaccaa ctaccagtac ttcgtaatat tgttcaaatc
     3421 attgaactta tcaataatcg agctggagaa gcggcttaaa ttctaaagtg attgccatgc
     3481 tgagactcat ttaaaattaa aaagagtaga aatttatgct atatatgaga agttttatta
     3541 ggaagaatgt catcgttttc ctagaataca gtatcagttg ttaagtggtt gataaatttc
     3601 aaagtagata cttgtaccac gatgtttgtt gatcgagtta ttaacaaaag agctactttg
     3661 attttaaaga aatagaaaac aaaaagccga gcaagaattc aattgcagga gaaaatgaaa
     3721 taatactcaa tgaaaatcaa agagcaaact aggaaactag ctgcaggctg ctcaaaacac
     3781 tgttttgagg ttgcagatgg aagctgacgc ggattgaaga gattttcgaa gagtataaat
     3841 cttcctagga taaagcaaaa cgcatagtat caagggtttt caacacttga tactatgcgt
     3901 tttctgatgt taaagacttt ctaccagttt ttttaagcat aattgttagt tgtagtcatt
     3961 tattattctt caaagaaaaa tggtggggcg aattttttca gttcttcaaa gcacttttga
     4021 gcagtatctg catcttcaca gatgataaga cagacatcat taccacaaag ggtagcgata
     4081 gcgtcaggga agctcaaagt atcaatgata gaaccaaagg attgagccag tccaggaagg
     4141 gtttttagta ggacttggtg ttgaactggg cgcatccaga caagggcgtc ttccatgtag
     4201 agttcgagac gtttttccca ttttgagatg gaaccattgt taagaacata ataagcgcta
     4261 tcttcttcgc ggacttttga taggttcata tttttgatgt cgcgtgagag ggttgcctgg
     4321 gttacttgaa tgtcgttctt agcaagaagg gcttgcaact cagcctgtgt atgaatcttg
     4381 ttttttgtga taagagcgcg tataagttgg tggcggtgtt ctgatttatt cataataatg
     4441 taactccttt tagcaaggta aggtaagcat ggactgagcg aggtcgacag tcaagtggta
     4501 gtctgtattg tcacggatgg tgatttcaaa gtcagtagta tagaggacta aacggagagt
     4561 gtctccttct tttagcttgt aaatagttgg ctgcagttca aattgaacat ccatccattc
     4621 atctgcagta atatcctcta ctaacagtaa atcatttcta ttttgtaaat taaggtaacc
     4681 ttttgtcacg actcgttgtg cctctggtct aaatggcaat tcacagagat tttccaacat
     4741 gtgatagcga ccgttgtcaa tggttctagc acttaaaata gctggataag gttgtaggta
     4801 tttcttttgc ccaaattcta gcagttgggc agataagagc cccttgtttg tactggattt
     4861 gatacgaaga ttgagctgag cgcgaccgtt taggtggaga tctttagtca caggaaggtt
     4921 aatagtaatc tgattggctt tcccttgata gagctctgta ttgaaggttt ggtatgtctt
     4981 accatagcgc tcaaaatcct tatctgggta ctggttttga atagcttgct cttcttgacc
     5041 aagtgagaag gtttcacagt tttcttgccc accgaagtta tcaagtgata accaagtctg
     5101 tggagctgta ttgtcctgcc agataacagt aggaagttga aagtctgttt cctgtcctag
     5161 taatttcttg gtcaataagg catttatgga ctcacggaag tcaattgatt gccaattgtt
     5221 catgtaaaca tgggcaccat tatggaaaaa gagatgcttg tttatatgag taggaagagc
     5281 atggaacatc tggtaaacat gaagtggttt gacattccaa tcctgagaac catgagtaaa
     5341 gacaacctct gcctttactt tatgggcatt gagcagataa ttgcggtcat gccaaaactg
     5401 attgtagtcc ccagtttttc ggtctagctg agctttcact ttttctaagt cagcttggtg
     5461 agcttcattg ccacggatat agtcgccagc taagagatta cgagaatagg ttaactcagc
     5521 aagggagtca aagtcctcac ctggataacc acctgggcta gtcaccagac cgttttcacg
     5581 gtagtagttg taccatgatg aaattcctgc ctcggcaatg ataacttcta aaccatcgac
     5641 tcctgtagtc gcaagaccat tggacatggt acctagatag gaaagtcctg ttgtagcaac
     5701 ttttccgttt gaccaatcag ccttgacttg acgctggcgc gtgtgatcag taaaggcacg
     5761 gcaacggccg ttaagccaat cgatgacatt tttataagcc tcgatttgct ggtagtctcc
     5821 attagtcatg aaacctgtcg agtctttggt accaacacct gagacataga gattggcaaa
     5881 gcctctcgga aggaagtagt cgtttagtgt atagctagag ttgatgtgag ttagcttttc
     5941 ctcagcctct gctataagct cagctttacc ttggggttgg acgagattta gttgaggttt
     6001 ctctagctca atcttgtgag gaagcttaac ctcaagctcg ccctccatct tgtagagagc
     6061 cttgtcacta gccttgtcat tggttccctg atgataaggg ctggctgtca tgatggcagg
     6121 gatttttcca tcaaaacgag ggcgaataat gctaaccttt actaggtctg atagcccttt
     6181 ttggtcagta tcgacacgag actcaacgta aacgacttca cgaatgacat cctggttaga
     6241 aaaagtagcc aaactcttgc cgttaaagta gtggtagtca ttatcctccg gaataagacc
     6301 atcactaaca agttggtcga taagagtatt tccttttttg gtgcgagtat tgagtaactg
     6361 atagagattt tcaatcaagt caccatatat aatgggaaat ccagtttctt tacgaaaaac
     6421 gtcactatct tcgaagtcaa ccaaataaga aaagcctaaa agttgaaaag caacagtata
     6481 aaaaatatct gctgtcagtt catcttctga ttgaaaaaat gtcagcaggt ctgttttttt
     6541 atcagctgct aggatcgaaa gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg
     6601 taaaaaggtt tcaagtgagt ctttgtgatt ggctgtattt tgtaaatcaa agccacattt
     6661 ttttagttca gataagacat tttcttttgg aaaattgata taactatatt gattaaaacg
     6721 catagaacct ccatatagaa tgacagttaa ggttattata tcaaaaaaaa agcagaaagg
     6781 gaattgttaa cttcaaaagg aaataatcca ataaaaatga ataaagcact aaattcaata
     6841 tagagaaca
//
LOCUS       DAVLTT010000080         6751 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLTT010000080 DAVLTT010000000
VERSION     DAVLTT010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6751
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.080"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            1..548
                     /locus_tag="VYN15_001902"
                     /pseudo
     CDS             1..548
                     /locus_tag="VYN15_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            609..1366
                     /locus_tag="VYN15_001903"
                     /pseudo
     CDS             609..1366
                     /locus_tag="VYN15_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            1543..2550
                     /gene="gap"
                     /locus_tag="VYN15_001904"
     CDS             1543..2550
                     /gene="gap"
                     /locus_tag="VYN15_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV1453176.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2617..3453)
                     /locus_tag="VYN15_001905"
     CDS             complement(2617..3453)
                     /locus_tag="VYN15_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1453177.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWKEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3579..5774
                     /locus_tag="VYN15_001906"
     CDS             3579..5774
                     /locus_tag="VYN15_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1453178.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEASWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5827..5979
                     /gene="rpmG"
                     /locus_tag="VYN15_001907"
     CDS             5827..5979
                     /gene="rpmG"
                     /locus_tag="VYN15_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1453179.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5989..6165
                     /gene="secE"
                     /locus_tag="VYN15_001908"
     CDS             5989..6165
                     /gene="secE"
                     /locus_tag="VYN15_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV1453180.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6220..>6751
                     /gene="nusG"
                     /locus_tag="VYN15_001909"
     CDS             6220..>6751
                     /gene="nusG"
                     /locus_tag="VYN15_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV1453181.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2100 a         1184 c         1454 g         2013 t
ORIGIN      
        1 actcgaaaaa aaagaaccac acctactatg aacaagaccc agaaaaagta gccttatttc
       61 ttaagaattt taatagttta aagcacctag cacctgttta gattgacgaa acaggattcg
      121 atacttattt ttatcgagaa tatggtcgct cattaaaagg tcagttaaga agaggcaaag
      181 tatctggaag aagatatcag agaatttctt tggttgcagg tctaacaaat ggtgaattaa
      241 tcgttccaat gacttacgaa gagacgatga cgagcgactt ttttgaagta tggtttcaga
      301 agtttttctt accaacatta aacacaccat cggttattat tatggataat gcaagattcc
      361 atagaatggg gaagctagaa cttttatgcg aagagtttgg gcataaactt ttacctcttc
      421 ctccctactc gcctgagtac aatcctattg agaaaacatg ggctcatatc aaaaagcacc
      481 tcaaaaaggt attaccaagt tgcaatacct tttacgaggc tcttttgtct tgttcttgtt
      541 tcaattgact atagttcacg gatacagttg ggaaagaagc tattaattat ttggagagtc
      601 cttttgggat gaacatgtca aatattacta tagatgggca agaaatggat ctgagtcaaa
      661 cgatgccttc ttatgctcaa gtagtgagtc tttatgagga tacaagcatc tctgttagta
      721 gtaatgagac ggacaaagtg ttggctggat ccctctatac tgatacaaat gaacagggat
      781 taacgattcc aagcagttta ctaaaaaatt ggaatgaaca gacaggaaaa aatttgacag
      841 ctaatgatct tattggcaaa tcagtctcag ccagcattat agaaagtgct gccgaaataa
      901 gaagtatact gtgctttctc aacagagagt tcttgatatt gtgattatct ttattcgtgt
      961 tattcaggga ttattgattg tgctttcatc acaagctatt gtggtagcag cggttatgat
     1021 tggtattatt atttacatca atatcatgca acgttccaag gaaataggtg tcatgaaagc
     1081 agttggttat cagaattgtg atgtcaaagg aatttttatt tacgaggcta tctggattgt
     1141 aggcatcgcc ttgctgctgg catttttggt tgcacaaggg gtgggaagtt tggcgaatgc
     1201 gattgtaagt cacttttacc catccatcac taaggttttt gaattaaatc ttttatctgt
     1261 tttaggaact ctagttttcg ctctattact tggttatgtc tcagcctact tcccggagcg
     1321 taagattagt aaaatggatc ctgtagaatc gttacgctat gaatagtaag ggattccttg
     1381 atttacagtc ttaaaaagaa actaacatag aaaaacaatg gccatacttg caattcaact
     1441 caaatagttg tataataggt ttgttgaaag gtgatttgta gtgattcaag ttactctttt
     1501 cacaataaaa atttcatgat tttcataagg aggaaatcac taatggtagt taaagttggt
     1561 attaacggtt tcggacgtat cggtcgtctt gctttccgtc gtatccaaaa cgtagaaggt
     1621 gttgaagtta cacgcatcaa cgaccttaca gatccagtta tgcttgcaca cttgttgaaa
     1681 tacgacacaa ctcaaggtcg tttcgacggt actgttgaag ttaaagaagg tggatttgaa
     1741 gttaacggta aattcatcaa agtttctgct gaacgtgatc cagaacaaat cgactgggct
     1801 actgacggtg tagaaatcgt tcttgaagct actggtttct ttgctaagaa agaagcagct
     1861 gaaaaacacc ttaaaggtgg agctaaaaaa gttgttatca ctgctcctgg tggaaacgac
     1921 gttaaaacag ttgtattcaa cactaaccac gacgttcttg acggtactga aacagttatc
     1981 tcaggtgctt catgtactac aaactgcttg gctccaatgg ctaaagctct tcaagacaac
     2041 tttggtgttg ttgaaggatt gatgactact atccacgctt acactggtga ccaaatgatc
     2101 cttgacggac cacaccgtgg tggtgacctt cgccgtgctc gcgctggtgc tgcaaacatc
     2161 gttcctaact caactggtgc tgcaaaagct atcggtcttg taatcccaga attgaatggt
     2221 aaacttgatg gatctgcaca acgcgttcca actccaactg gatcagttac tgaattggta
     2281 gcagttcttg aaaagaacgt tactgttgat gaagtgaacg cagctatgaa agcagcttca
     2341 aacgaatcat acggttacac agaagatcca atcgtatctt cagatatcgt aggtatgtct
     2401 tacggttcat tgtttgacgc aactcaaact aaagttcttg acgttgacgg taaacaattg
     2461 gttaaagttg tatcatggta cgacaacgaa atgtcataca ctgcacaact tgttcgtact
     2521 cttgaatact tcgcaaaaat tgctaaataa ttcttgagtt gatagaaagc aaggctttgt
     2581 ggtcttgctt tttatatgga aaaatggatg acacgatcat ccattctttt ttaattcttt
     2641 ttcaaatgta tttgaaaggg tagtgaaagt tagcttctct aaagtaagtg ggtgggtaaa
     2701 ggaaagtcgg aaggcatgaa gcataagccg acttgtcttt gatttactat tatagagagg
     2761 gtcgcccagg ataggaagat tatgatgcga aaggtgcaca cgaatctgat gggttcgccc
     2821 tgtctttagc ttgcaacgag ccaaggaagt cttgtttgag aattgcttta atctgcttac
     2881 atgcgtttca gcatattgcc cattttttgc atcaactatt ctttttctac gatcatggcg
     2941 atcacgtcca attttgtctc tgaaaacaag ttcttttctg ttgatatttc catcaactag
     3001 agcccaatat tctctagaaa tctctttttt ctccaataag cgattgagaa tgggcaggat
     3061 aaaaggattt ttggcaaaga gaactaagcc actggtttcc atgtccagac gatgaacgac
     3121 atagcaggtt tggccaacat aggtactgac atggttaaga agggcaattt cgtttggttg
     3181 attaccatgc gttttcatcc cctctggttt gtttacaata atcaagtgtt gatcttgata
     3241 aacttcctgc actaagtctg ggttgcccca agggatcgtc ttttgggaat aatcttcctc
     3301 gtcaaaagtc aactggcaaa catctccagg atttacgatt tccttccagt ggacttcttc
     3361 ttgatttatc aaaatatgtt tcttgattct caaaaaatga cggatttttc tagggatgag
     3421 gagttgttcc tcaagtaatt gctttactgt catttgaggt agagaggcgg gtaatgtaaa
     3481 tgtgaattgc atacagatat tgtaacaaaa aaagccctat ttggatagga aatagctaaa
     3541 ttcttgtctt cctatgatga agatgataaa ataaacgcat gaaattagat aaattatttg
     3601 agaaatttct ttctcttttt aaaaaagaaa caagtgaact agaggactct gattctacta
     3661 tcttacgtcg ctctcgtagt gatcgaaaaa aattagccca agtaggtccg attcgaaaat
     3721 tctggcgtcg ttatcatcta acaaagatta tccttatact aggtttgagt gcaggcttgc
     3781 tagttggaat ctatttgttt gctgtagcca agtcgaccaa tgtcaatgat ttgcaaaatg
     3841 ccttgaaaac tcggactctt atttttgacc gtgaagaaaa agaggctggt gccttgtctg
     3901 gtcaaaaggg aacctatgtt gagctgactg acatcagtaa aaacttgcag aatgctgtta
     3961 ttgcgacaga agaccgttct ttctataaaa atgacgggat taactatggc cgttttttct
     4021 tggctattgt cactgctgga cgttcaggtg gtggctctac cattacccaa cagctggcta
     4081 aaaacgccta tttatcgcag gatcaaactg ttgagagaaa agcgaaagaa tttttccttg
     4141 ccttagaatt aagcaaaaaa tatagtaagg agcaaattct aaccatgtac cttaacaacg
     4201 cttattttgg aaatggtgtg tggggtgtag aagatgcgag taagaaatac tttggagttt
     4261 ctgcatcaga agtgagtctg gatcaagctg cgactctggc agggatgctc aaggggccgg
     4321 aactgtataa tcccttgaat tccgtagaag attctactaa tcggcgcgat actgtcttgc
     4381 agaatatggt tgcagcagga tatattgata aaaaccaaga aaccgaagct gctgaagttg
     4441 atatgacttc gcaattgcac gataagtatg aaggaaaaat ctcagattac cgttacccct
     4501 cttattttga tgcggtggtt aatgaagctg tttccaagta taatctaaca gaggaagaga
     4561 ttgtcaataa tggctaccgc atttacacag agctggacca aaactaccaa gcaaatatgc
     4621 agattgttta tgaaaacaca tcgctatttc cgagggcaga ggatggaacg tttgctcaat
     4681 caggaagtgt agccctcgaa ccgaaaacag ggggagttcg tggagttgtc ggtcaagttg
     4741 ctgacaatga taaaactgga ttccggaatt tcaactatgc aacccaatca aagcgtagtc
     4801 ctggttctac aattaagcct ttagttgttt atacgccagc agttgaagca agctgggctt
     4861 tgaataagca gttggataac cataccatgc agtatgacag ctataaggtt gataactatg
     4921 cagggatcaa aacgagtcga gaagttccta tgtatcaagc cttggcagaa tcgcttaatc
     4981 tacctgctgt tgccactgtt aatgatttgg gtgtcgacaa ggcttttgag gcaggcgaaa
     5041 aattcggact caacatggaa aaggtcgacc gtgttcttgg tgtcgccttg ggaagcggtg
     5101 ttgaaaccaa ccctcttcaa atggctcaag catacgccgc ctttgcaaat gaaggtttaa
     5161 tgcctgaagc tcattttatt agtagaattg aaaatgctag tggacaagtt attgcgaatc
     5221 ataaaaattc acaaaaacgg gtgattgata agtctgtagc tgacaagatg accagtatga
     5281 tgttggggac tttcaccaac ggtaccggta ttagttcatc gcctgcagac tatgtcatgg
     5341 cagggaaaac tggaacaact gaagcagttt tcaatccgga gtacacaagt gaccagtggg
     5401 taattggtta tactccggat gtagtgatta gccactggct tggctttccg accactgatg
     5461 aaaatcacta tctagctggc tctacttcaa acggtgcagc tcatgtcttt agaaacattg
     5521 ccaataccat tttaccttat acgccaggaa gtacctttac ggttgaaaat gcttataagc
     5581 aaaatggaat tgcaccagcc aatacaaaaa gacaagtaca aaccaatgat aatagccaga
     5641 cagatgataa tttgtctgat attcgagggc gtgcgcaaag tctagtagat gaggctagcc
     5701 gggctatctc agatgcgaag attaaggaaa aggctcaaac aatatgggat tcgatagtca
     5761 atctatttcg ctaagatgct tgtcaaagcc tagctttctt gttataatgg ataagatgga
     5821 ggcgttatgg cactaaaaaa agcaagccta gcttgtgcgg tttgtggttc gagaaactat
     5881 tcaatcaaga tcagcggaaa ccccaagcct acacgactag aagtaaataa attttgtaag
     5941 cattgtggca agtacactac acacagagaa acgagatagg agagagcgat gcgttttatt
     6001 ggagatattt ttagacttct taaagacaca acgtggccaa ctcgcaagga aagctggaga
     6061 gattttcgtt ctatcatgga atacacagct ttctttgtag taattattta catttttgac
     6121 cagttgattg tttcaggttt gattcgattt attaacattt tttagaagat tagtggagtt
     6181 aattacacta gaaatcttct atttatgaaa ggaaatatca tggatagttt tgataaagga
     6241 tggtttgttt tacaaactta ttctggttat gaaaataagg tgaaagaaaa tctattacaa
     6301 cgtgcacaaa cctacaatat gttggataat attctacgcg ttgaaattcc aacacaaaca
     6361 gtgcaagttg aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt tccaggttat
     6421 gttcttgtag aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa cacaccaaat
     6481 gttacaggat ttgtcggatc acacgggaac agatcaaaac caactccatt attggaacaa
     6541 gaaattcgcg acattttggt atctatggga caaactgttc aagaatttga tttcgatgtt
     6601 gagattggtc aaactgtacg tattattgat ggtgcttttg cagactacac tggtaagatt
     6661 acagaaattg ataataacaa agtgaaaatg attatctcta tgtttggtaa tgacacagtt
     6721 gcagaagtaa atctaaacca aatcgcagaa t
//
LOCUS       DAVLTT010000081         6644 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLTT010000081 DAVLTT010000000
VERSION     DAVLTT010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.081"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            219..887
                     /locus_tag="VYN15_001910"
     CDS             219..887
                     /locus_tag="VYN15_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1453182.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LSQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            847..1524
                     /locus_tag="VYN15_001911"
     CDS             847..1524
                     /locus_tag="VYN15_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1453183.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSVIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILILYFAVCYPISKLSTH
                     LEKHWRN"
     gene            1525..2283
                     /locus_tag="VYN15_001912"
                     /pseudo
     CDS             1525..2283
                     /locus_tag="VYN15_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            2295..3155
                     /locus_tag="VYN15_001913"
     CDS             2295..3155
                     /locus_tag="VYN15_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1453184.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAK
                     ADDLVVEGGH"
     gene            complement(3235..3882)
                     /locus_tag="VYN15_001914"
     CDS             complement(3235..3882)
                     /locus_tag="VYN15_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1453185.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(3879..4577)
                     /locus_tag="VYN15_001915"
     CDS             complement(3879..4577)
                     /locus_tag="VYN15_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453186.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(4587..5339)
                     /locus_tag="VYN15_001916"
     CDS             complement(4587..5339)
                     /locus_tag="VYN15_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453187.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKYFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(5339..6103)
                     /locus_tag="VYN15_001917"
     CDS             complement(5339..6103)
                     /locus_tag="VYN15_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453188.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(6199..6602)
                     /locus_tag="VYN15_001918"
                     /pseudo
     CDS             complement(6199..6602)
                     /locus_tag="VYN15_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2251 a         1377 c         1077 g         1939 t
ORIGIN      
        1 cctccttaat aagtaagcgt ttactttgtg tattacaaaa atatcttaac tctttttcaa
       61 aacttttaaa atattttgtt tggaaatttc agaaatttta tgtctatgat aaaaatcctt
      121 ataacggcaa taaaaaatag atattatcca aagaagattt taagtgctac aataactgta
      181 ttatttctag atgggaggtt ctatttttgg attgatccat tgttgaacaa tatctaccac
      241 tatatcaaaa ggcattcttt ctgaccttgc atattgcagt ttggggaatt ttgggatcct
      301 ttctgctcgg tttaatcgtt agtatcatcc gacattatcg aatccttgtt ttgtcgcaag
      361 tagcgacagc ctacattgaa ttgtcacgta atacgcccct tttgattcaa ctcttctttc
      421 tctacttcgg tcttccccga atcgggattg tcctatcttc agaagtctgt gcaacgcttg
      481 ggcttgtctt tttaggaggc tcctatatgg cagaatcttt ccgaagtggg ctggaagcca
      541 tcagtcaaac ccagcaggag attggcctcg ctattggtct gacacctcta caggtctttt
      601 actatgtggt tcttccgcaa gcaacagcgg tggcactccc ctcctttagt gccaatgtca
      661 ttttccttat caaggaaacc tctgttttct cagcagtggc tttggccgac ctcatgtacg
      721 tcgccaagga tttgattggt ctctactatg agacagacat tgcgctagct atgttggtag
      781 ttgcttatct gatcatgctg ctacccatct cactggtctt tagctggata gaaaggaggc
      841 tccgccatgc aggattcggg aatccaagta ctctttcaag gaaataatct cctgagaatc
      901 ttacagggat tgggcgttac gattgggata tccatcctgt ctgtcctctt atccatgatg
      961 ttcggaacag tcatgggaat catcatgacc tcccattcta gaatcatacg atttttaaca
     1021 cgattgtatc tggaatttat ccgtatcatg ccccagctgg tgctactctt catcgtttac
     1081 tttggcttgg ctcgaaactt taatatcaat atctcaggtg agacttcagt tattatcgtt
     1141 tttaccctct ggggaacagc tgaaatggga gacttggtac gtggagctat cacttctctc
     1201 cctaaacatc agtttgaaag tggacaggca ctcggcttga ctaatgttca actttactac
     1261 cacatcatca tcccacaagt cttgagaaga ctgctaccgc aggctatcaa tcttgtcact
     1321 cggatgatta aaaccacttc attagttgtt ttgattgggg ttgtggaagt gaccaaagtt
     1381 ggacaacaaa tcatcgatag caatcgcctg accatcccaa ctgcttcatt ttggatttat
     1441 ggaaccattc taatcttata tttcgcagtt tgctacccta tttccaaact atccactcac
     1501 ttagaaaaac attggagaaa ctaaatgtct gaaactatct tagaaatcaa ggaactaaaa
     1561 aaatccttcg gagacaatcc catcctccaa ggactttctc tagaaatcaa aaaaggggaa
     1621 gttgttgtca tcctagggcc atctggttgt gggaaaagta ccctccttcg ttgcctcaac
     1681 ggcttagaaa gtattcaagg tggagatatt cttctggatg gtcagtctat cgttgaaaat
     1741 aaaaaagatt ttcacctagt tcgccaaaag attggcatgg tcttttaaag ttatgaactc
     1801 tttccccatc tggatgtctt acaaaacctc atcctaggcc ctatcaaaac tcaaggatgg
     1861 gacaagaaag aagtaacgga agaagctttg caattactag atcgtgtcgg tttgctggat
     1921 aaacaacata gctttgcccg tcaattatct ggtggacaga agcaacgtgt tgcaattgtc
     1981 cgtgccctcc taatgcatcc agaaatcatc ctttttgacg aggtgactgc ttcgctggat
     2041 ccagaaatgg tgcgtgaggt gctggaactt atcaatgatt tggcccaaga aggccgtacc
     2101 atgattttag taacccacga aatgcagttt gcccaagcca ttgctgaccg gattatcttc
     2161 ctcgaccaag ggaaaatcgc tgaagaagga acagctcaag ccttctttat caatccgcaa
     2221 accaaacgag cccaggaatt tttaaacgtc tttgacttta gccaattcgg ctcatatcta
     2281 taaaggagat tcttatgaaa ctattcaaac cactcttaac tgttttagca cttgcctttg
     2341 cccttatctt tatcactgct tgtagctcag gtggaaacgc tggttcatcc tctggaaaaa
     2401 caactgccaa agctcgcact atcgatgaaa tcaaaaaaag cggtgaactg cgaatcgccg
     2461 tgtttggaga taaaaaaccg tttggctacg ttgacaatga tggttcttac caaggctacg
     2521 atattgaact agggaaccaa ctagctcaag accttggtgt caaggttaaa tacatttcag
     2581 tcgatgctgc caaccgtgcg gaatacttga tttcaaacaa ggtagatatt actcttgcta
     2641 actttacagt aactgacgaa cgtaagaaac aagttgattt tgcccttcca tatatgaaag
     2701 tttctctggg tgtcgtatca cctaagactg gtctcattac agacgtcaaa caacttgaag
     2761 gtaaaacctt aattgtcaca aaaggaacga ctgctgagac ttattttgaa aagaatcatc
     2821 cagaaatcaa actccaaaaa tacgaccaat acagtgactc ttaccaagct cttcttgacg
     2881 gacgtggaga tgccttttca actgacaata cggaagttct agcttgggcg cttgaaaata
     2941 aaggatttga agtaggaatt acttccctcg gtgatcccga taccattgcg gcagcagttc
     3001 aaaaaggcaa ccaagaattg ctagacttca tcaataaaga tattgaaaaa ttaggcaagg
     3061 aaaacttctt ccacaaggcc tatgaaaaaa cacttcaccc aacctacggt gacgctgcta
     3121 aagcagatga cctggttgtt gaaggtggcc attaactctt aaaagggact ggattttaag
     3181 ctccaatccc tttttaagat tttacctata acatcctgag tctatctaag atgttcaatc
     3241 tgaacacagt gtacatactt tatcttctat tgcatatact ttatcacata agatacgaat
     3301 atcctcttca ctatgactag caatcaaaat tgttgtccct ttttcactag agagctttct
     3361 aaacaatgtt ctcatatttt ctacacttga tttatccaag gcattcatag gttcatctag
     3421 taaaagaata gagggattct ccataattgc ttgagcaatc cctagctttt tcctcatacc
     3481 tagcgaataa gttttaactt tctggtcttt ttgctcatat agaccaacta ttttcagtgt
     3541 atcattgatt tcctgattac caactactcc tcgtatgctt gccaaatatt gtaaattctt
     3601 aaagccacta taataattta taaaaccagg ttcttcaatc aaagctccca aattagctgg
     3661 aatttttctc tcaggaacaa tattttcccc attgattaac acttctccat aagacggact
     3721 atataaacca gctattaatt taaacaatac acttttccct gagccattcg caccagtaat
     3781 tcctataatt tccccctgtt tacaactaaa gttaaggttt tgaaaaacac atgtcttttt
     3841 taatttcaac tcaatatttt ttaatatgat tatttcattc attctataaa cctcctcttt
     3901 tgacgagtga aatagaaaat gctttgaaaa agaaagacta aaaatagcaa ctgaagaaat
     3961 aaatctcgtc ctatatctcc attccctcga ttcaaaatat aaaatagata attagttcga
     4021 tttcctacaa atagaccacc aaacacaatc atgagtaaaa agaaactaac gcaagcaaag
     4081 ttcatttgta cattcgctcc tagtgcgtat aacataaagc aaaacaagac taacacacaa
     4141 gcattcaaag aatcaactat aaacaaaact cctatatccc agtttggtaa ctgtaacata
     4201 aattgaatca ctagaacttt taccatgatt aaaatgagtc cataaagaaa acaggtccaa
     4261 atctgatacc taatccagag cttaatagaa gaaaatcgaa tcacttccat aaagaaatcg
     4321 gatgctcttc tacgatatac aactgctaga aaaaatgtat gaataataaa ccaatgaagc
     4381 aaccatatag ataagactaa aaaagagttt tgactcagat taggcccttt taaaatttct
     4441 ataacaagtc tatcatttcc ttctaaccaa taccataatc ctaaacaaat caatatccaa
     4501 aaaagaacat aaccccaaaa gtacttggta tagattatct gattcaacct ccacatgtga
     4561 ctacttaact ttcccatttc caacttttac actctcctcc agtttctatg aacagaaaat
     4621 acagtcaatg gaattatgat agatagtaat gtaagccaat aaatcaatgc atacggattg
     4681 gaatttacca tatactgaaa aattggcaat aatccaatta tcccattgtt caactgataa
     4741 atccagaata aggattctac aaataaaaaa gtaaacagaa atactaagct catgtttgat
     4801 tttttaaacc aagaaaaact gctaatagta agtaaggata aaaagaaata gtatgctata
     4861 taagagaaaa aaaatcctat aaagaaacta gcattgtttg caatacttat accataaaat
     4921 tctcttaaaa aatcaacctc ctttatctcc aaagagaagc taaaaccatt actaaatgca
     4981 attagaaaaa tcaataaaaa taaagtcgcc gtccaaatcc ccgtactaag agctgctaat
     5041 ttgaaactaa aactggtaaa gtacttaatt gatttcagac gaatgcgaca ctccaaccta
     5101 ttaaaatagt tattcatcaa ataaaaaaag aacaatatat atgtgaacgg aaagcagtat
     5161 actccagtcg tcatatcttg aagtaagact aagatccatt ctaatacatt tggatggatt
     5221 gaatattggc gacagcgcaa taaatatact gtactagata aaacacagga tagcagtaat
     5281 ataaaataaa ccaatactgc taagaaatct tttttataaa attgaacaaa ttgtttcatt
     5341 atacatagtc ctctgaatgt agaaaaaatg taccataaac aaccaaacaa ctaacaaata
     5401 aaataaaagc aagatgccca ctaactaagg aaagactgat atctttctga tatcccaaag
     5461 ctaatgttgt cacaggttct aagtaagata gccctaaaat agcccaaaaa ataccaccaa
     5521 ccatcatata ggcaactggg atgaaaatag ctcctatttt tttcttcact agcaaagcac
     5581 tagctagtcc aaaaatagag aacacagcgc cccaaactcc ataccagaga gtcgtcacaa
     5641 gactatagag caactgattg gaatcaaata attcttttaa ggcaccacta taatctccaa
     5701 tataaatttc ctgataagga gtcactaaaa gattaattcc taataataat aaatagggga
     5761 gaaaaaagac tagaaaagaa gaaataattg cagtactacc cacaatagcc agatacttct
     5821 ttttagaaat tcgacacaat tgtgctgtta gaaaatgact ctcagcatcc tctattatct
     5881 gactagaata gggcagtgta cagataagtg cagctactag gctaatcggt gaaaatcctc
     5941 gaatagaaga agcggcaaaa aaaatggata aaccttcaat tttataaata ccattgaaag
     6001 caaggaaatt tcctaaactc atgcaaagaa gggtcaaaaa taaagacata taaaatcgag
     6061 gtgattgaac gactcgtaca agattacaaa tgaaaaattc catccttact cctccttata
     6121 ataaaaatag ggtgtagcat tcttttttca tgctacaccc acaatcaacc atctttaagg
     6181 cttactctga caagtaagtt aataagaatc tggactccaa gaacctgaag tatgaattct
     6241 tacatgattt ccaaattgtg gcgccatagc taatctagta ccagaaccaa tataattgtc
     6301 accacctcca ttatagtaca tgacaatcct agagccagac cccaatgaat ataccggggt
     6361 aatatctgac ccactatagg cgctacgaat agaggtattt aaccttttac cgccaccaat
     6421 gctgtcatta ttattaattc cagcagaggc gttttctttc tcaagctcac tagttgtatc
     6481 cgaaccccaa cgcggcaacg ttaaatcata atctccaatc tgtctagcta aaactgtaag
     6541 gagaaacaaa ctagatgcaa ttgtaactac gcaaaaaagg aatatatttt tcttcttttc
     6601 atgacatcgt cctcctaaga agtgataaac aagatagttg attg
//
LOCUS       DAVLTT010000082         6570 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLTT010000082 DAVLTT010000000
VERSION     DAVLTT010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6570
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.082"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            62..748
                     /locus_tag="VYN15_001919"
     CDS             62..748
                     /locus_tag="VYN15_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1453189.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            749..1681
                     /locus_tag="VYN15_001920"
     CDS             749..1681
                     /locus_tag="VYN15_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1453190.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1692..2621
                     /locus_tag="VYN15_001921"
     CDS             1692..2621
                     /locus_tag="VYN15_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1453191.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2635..4074
                     /locus_tag="VYN15_001922"
     CDS             2635..4074
                     /locus_tag="VYN15_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453192.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4143..5720
                     /locus_tag="VYN15_001923"
     CDS             4143..5720
                     /locus_tag="VYN15_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1453193.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPKINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5780..>6570
                     /locus_tag="VYN15_001924"
     CDS             5780..>6570
                     /locus_tag="VYN15_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1453194.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNIEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFR"
BASE COUNT         2248 a          885 c         1270 g         2167 t
ORIGIN      
        1 aataaaattg tagtagatgt tattgaatta gtaaaaaaat aaaaaaacgg aggttttctg
       61 aatggaaact aaaaaaatta aaaatttaaa aggtcaaata attgtttcct gccaagcgtt
      121 agaaggagag ccactttata ctccaaatgg aggagtgatg ccgttattag caaaagccgc
      181 ctttcaagca ggcgctaaag gtattcgtgc taattctgtc cgcgatattt cagaaataaa
      241 agaagaagtt gacttaccaa ttataggtat cataaaaaga gattacgatg gctttgaacc
      301 ttttatttca gcaactatga aagagattga tgaattagtt agtgaaggag tagacatttt
      361 agctttggat tgtactaatc gttcaagacc aggttatgat aatattactg actttattca
      421 tgatattaaa gtcaagtatc caaaccaatt attaatggct gatatttcta cttttgaaga
      481 agggaaagta gctgctgaat cgggagtaga ttttgtgggt acgacattat ctggttatac
      541 accatatagc cctaaaaaag ataatcctga ttttgagtta gttgaaagat tggtaaaaga
      601 gcttgacgta ccagttattg ctgaaggaag aataagtact ccggaacaag ctagaaaaat
      661 gttagattta ggtgcttacg cagtggttgt tggaggagct atcactcgtc ctttggaaat
      721 agcgaagaag tttattgagg tagtttagat gaatcaagaa atattaaaaa agagtaagat
      781 tcaattgaca gttgaacata ttcaaaaata ttggatttta tatttaatga tgattccagc
      841 aactgttcta ctaattttat ttacgtatgg accaatgtac ggcattatta tggcctttca
      901 agactttact gtcttcaagg gatatactgg aagtccattt gtcggtttaa aacattttca
      961 aagattgttc tcagatcctt tgttttatag attgttcaag aatacgttca tggtaggggt
     1021 tttagacttt ttattctctt tcccagctcc gcttattttt gcactcatat taaacgaagt
     1081 cagaaaagta agatttaaga gtgtagttca atctattagt tatcttcctc attttattcc
     1141 cctagtggtt atggttggta ttatttttga actatttggt tcatatggta ttattaacag
     1201 tttactttca tcacttggaa tggagccaat aagtttcttt acaaaatctg aatggttctt
     1261 gcctctctac attggttcag gagtatggaa aacaataggt tggggttcta tcatttatat
     1321 gggagcatta accaatatag attcaacttt atatgaagca gcagatatgg acggggctaa
     1381 tagatggcac aaaatgtggc atgtaactct accaagttta agacctacag tagttacttt
     1441 gtttatacta aatgctggtg gtatcatgca agtaggattt gaaaaggtat tcttgatgtc
     1501 tagtcctgca acatatgaag tatctgatgt attatctact tatgtttata gacaaggtat
     1561 tttaaattct gatttcagtt actcagctgc agtaggatta tttaataaca tagtagcttt
     1621 gttatttgtt ttattagcta ataagattgc taaaaaactt ggcgaagaag gaattgtata
     1681 aggggggtaa aatgattttt tcaaaaaata caaaaaagag taatagagac aaagaaacct
     1741 tcgttgatta tctctttata ttcattttaa taataataac cttacttatg ttgtatccat
     1801 tatggtgggt agtgatgacg tcactttcag aaccagtttg gctatctaaa aacgttgtta
     1861 aattatttcc cttaaaaata gatattactg catataagtt tatttttggg gattctaaac
     1921 tatggcaagc atatggtaat agtgtattgt atgctgcact atctacaatt gttagtgttg
     1981 cggtatgtag tatgtatgcc tatccactta caattcctga aattaggggt aaaaaattct
     2041 ggaatactct tattttgatt ccaatgttct ttagtggagg aatgatcccg ctttatatac
     2101 aagttgcaaa cctcggttta ttgaatactg cttgggctct tgttttacct ggtgctgttt
     2161 ctacatatta tataattttg tttagaacac agtttaaatc aatcccaatg gagcttcgtg
     2221 agtctgctag aattgatggg gcaagtgaat ttagaatttt ttggaattta gtattaccat
     2281 tatcaaaagt tattttcatg attatagcac tttattgcat agttggttca tggaatagtt
     2341 ttactcctcc attactttat ttgaatgacg acactaagat gcctttatct atttatttga
     2401 gaaatttagt tgttacaaat acaactgata ctgctgaatt atcactttct gcaggtaata
     2461 catattacca acaaattgct gctcaaggtg gaggtattgg tatgcgtatt gctattaaga
     2521 tgggtactat tgttgttagt gttattccaa ttatgatgat ttatccattt attcagaaac
     2581 attttgttaa gggaatcctg ctaggttctg tgaaaggtta ataaggtaat tattttgcaa
     2641 aatttaaaaa aatatctttt attagatagc ggtttagtag ttgggtatac attagaaaat
     2701 gctcaattaa aattaaataa gctaaaaaaa gatactgaaa acaatccact atttggtgaa
     2761 gagtattttg ccgaaaatcc taaattatgg gaagttcgtt ttgataattc atatccaaac
     2821 gttatctatg ataaagaatt gaaattatat agatgttggt atcaaacatt tgttagtgat
     2881 gaagcaagcg aagagactcc tttagcagaa cgtggagaga aggaatacat tgtcaagtca
     2941 tctagaatga cagcactttg ctatgctgaa agtaaagatg gagtaaaatg ggaaaaacca
     3001 aatctcaatc tagtaaaatt taaaggttca aaagataata atattgttct gatgcatgca
     3061 cacggtgcag gtatcatgct agatgaacag gagttggatc ctaagaaacg atataaatta
     3121 gtttcaaaat tagaattttc tccgaatctt cattacatgg ttgttgtttt ttcagaagac
     3181 ggtattcatt ttgacgaacc tattccatgg aaaaaatgga atcctgcagc agatagtcat
     3241 aattttccat ttagagatcc aaaaactggt aaatacgctg ttattacaag aacctgggca
     3301 aataacgtac gtctaagtgc aattactttc agtgatgatt ttattaattg gtcagaacct
     3361 aaagaaatcc ttaggggaga tggatttgaa gatcaaattt attctatgcc agtaatttca
     3421 tacgcggata tctatttagg ttttgcttca atgtaccacg aaggcgacac tttaaatgaa
     3481 aactatgata aagtagactt agaattgaaa ttctctgcta atttggaaca atgggatagt
     3541 gtatgtaagg gcgactatct cattgaaagg ggaggtggag tatacccgca gaatgctgat
     3601 tttgatgcta gttgtatttt cacggctgct ccaataattg aagatgataa gatttggttc
     3661 tactatatgg gtggaaatgg taatcacact ggcttccgag aaagttcatt agctagagga
     3721 tatattaaga aagaccaatt tgcttattat actaataaga gagaaggaat tccagctaaa
     3781 atatctacag ttagcttcca aacttacgat gatgaaattt atatcttagc tgatattcct
     3841 gaaaatggtt atattaaagt tgcggtaggt actaaatacg gtaatgctta ttcagatttt
     3901 ggtcaggaag atatctctct tgttcaagtt tccgatggta agtataagtt ggaatttaat
     3961 aaaaaatcta tcttagattt aggtaattct ccagttgcgt tcaaatttga aatcgagaat
     4021 gcaaaattgt atggtattga aggtagtatt cagcaacact atctcaaata ttaaccagaa
     4081 taattcgtta acaaataatc tctatattag tggagataga tatataaaat ggaggtctta
     4141 ttatggtaaa gcttaataag gtattaaaag ggagtgttgc attcctgagt gcaagtttat
     4201 tgctagcagc ttgtggcaat aacgctaatt caaagcccgc tgaaaaaaca gctgatggta
     4261 aaacgaaaat ttcgtttcta tctacatggc aaattaatga tgttcgtccg cctaaagatg
     4321 aaacacttgt tggtcaatgg ttagaagaac agctaggtat tgatattgat cttgtaacta
     4381 ttcctggcga gggagtaagt tctaaagtaa attctcttat tactagtaac cagttaccga
     4441 ctgttttgtt gacaacagga gataagagtg atatcgctgg tatcaacaaa cttggtaaac
     4501 agggtgcatt cttagatttg tcacaacaca tggacaaact accaaactat aagaagtacc
     4561 ttgaaaaaaa taatgcatta gctcaaatag aagatgatga aaaacatatt tatgctttca
     4621 caaaattctt tactgatgag aatatcatgt atactacacc aattctgaga aaagacttac
     4681 ttgttggttc agaatttgaa gatctttcaa aaattaaaac tgttgatgac tatacaaaag
     4741 ttttgaaata tttgactgaa aaacaaggtt ctccagcatt tattcaacgt aatggctatg
     4801 aaggcttcat gaagcgagtt acaccattgt ggaatttaag ccatcgtaca tactatgact
     4861 atgaatcaga ttcatataaa catccagttg aacaacctca attgaaacaa ttcgttgaat
     4921 ggttgaaaga attacgtaaa gataacgtac ttcaccctga ctgggcagtt atgaaagatg
     4981 aaacttggga aggtctattg gcttctaaca agggttcatt cactgttgac cgtatgaata
     5041 tcattggaga taataacttt gataaatcat ttgattggca gccacttgtt tatccaaaaa
     5101 ttaatggaaa acgttatttg caaccgaaaa caccgtacat ttctgattca ggttgggtaa
     5161 tcaatgccaa tgcaccaaaa gaagaaattg ataaagcgtt agaattcttt aatttcttat
     5221 acgctgatga aaatcaagaa aaacttgcta ttggatttga aggtaaaaca tttacacgtg
     5281 aaaaccctaa tactcaagca ggtattaaat ggttgattca aatttacggt gaaaatgctg
     5341 gaaatgataa agcagaactg ctgtttaaac atggtaacca agcatttact cgcgttcaaa
     5401 ctaaattaga tattgaggca cagccaggaa cattccctaa agttatgtat gatcaagtag
     5461 ataaaattaa gaaagattta ggtggtttta gaccagatac tccggttctt tcctttacaa
     5521 ctgaagaatt agatgtttta actaaatctg aagcaggatt aaatactttc tttgatgaaa
     5581 atattattaa attcattgaa ggacaaagag atatgagtga gtgggattca tttatcaatg
     5641 aagctaaatc taaagacttg gataaagtta caaaagtata taatgatgcc tacaaacgtg
     5701 tcaaagatag aatgaaatag actaaatggt agctctctgg tttttcagag agctactact
     5761 gcctgagggg gagtaagctt tgtatgatgt agtaattata ggtgcaggaa gttcgggcgc
     5821 attggctgca attgcttcgg ggcgtctagg gttaaaaact tgtctaatag agaagggaag
     5881 tagaattggt ggagttccta ttaatacact aatggggtca tttgctaatc tatattttga
     5941 tgattctggt agagtaaatg caagtaaaat tgttggggaa ttaatagaac gtattatcaa
     6001 aaaaggtggt actgtcttta actctatgga agaattgatg aatgtaaatg atttttatca
     6061 gattacaatt ccctatcaac cagaagttta tgaatcggtt ttaactgata tgttgattga
     6121 gtctaaagtt gatattttac taaatattga agttaataat attatttatg atagtaaaaa
     6181 tattaaaagt cttgaaattt taagtaatca ggaagttaaa ttgattgatt ctaaagtttt
     6241 tattgatgct acagggaatg caacaattgc ttctgctagt ggagctgatg tttatgaaaa
     6301 aaattcttct tacggttgtt taatgagagt tggaggagtt gatatctcaa agactataga
     6361 acatattgaa aaaacaaagc agtggaacta tatagaagga tataatcagt ggttagaaga
     6421 agtattagca aatcgaaagt acagagccac tggagcagtt ttaaaagatc cagtttctta
     6481 tgatcatgcc cctatgcttt caaaagacga ccattttatg aatgatgaaa aatggaatta
     6541 cattaaagaa agatgggaaa aatttagatt
//
LOCUS       DAVLTT010000083         6205 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLTT010000083 DAVLTT010000000
VERSION     DAVLTT010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6205
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.083"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            1..185
                     /locus_tag="VYN15_001925"
                     /pseudo
     CDS             1..185
                     /locus_tag="VYN15_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            352..552
                     /locus_tag="VYN15_001926"
     CDS             352..552
                     /locus_tag="VYN15_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453195.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            594..998
                     /locus_tag="VYN15_001927"
     CDS             594..998
                     /locus_tag="VYN15_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453196.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1229..1936
                     /gene="ccdA2"
                     /locus_tag="VYN15_001928"
     CDS             1229..1936
                     /gene="ccdA2"
                     /locus_tag="VYN15_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1453197.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1947..2504
                     /gene="sdbB"
                     /locus_tag="VYN15_001929"
     CDS             1947..2504
                     /gene="sdbB"
                     /locus_tag="VYN15_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV1453198.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2878..4269
                     /locus_tag="VYN15_001930"
     CDS             2878..4269
                     /locus_tag="VYN15_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV1453199.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYRIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4412..5329
                     /gene="adcAII"
                     /locus_tag="VYN15_001931"
     CDS             4412..5329
                     /gene="adcAII"
                     /locus_tag="VYN15_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV1453200.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5337..>6205
                     /gene="phtD"
                     /locus_tag="VYN15_001932"
     CDS             5337..>6205
                     /gene="phtD"
                     /locus_tag="VYN15_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV1453201.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHV"
BASE COUNT         1896 a         1113 c         1317 g         1879 t
ORIGIN      
        1 gtcagttaat aagaggcaaa gtatctggaa gaagatatca gaggatttct ttggttgcag
       61 gtctaacaaa tggtgaatta atcgctccaa tgacttacga agagatgatg acgagcgact
      121 tttttgaagt atggtttcag aagtttttct taccaacatt aaccacacca tcggttatta
      181 tagtaaaatg aaataagaat aggacaaatc gatcaggaca gtaaaatcga attctaacaa
      241 tgttttagaa gtccatatgt actattctag tttcaatata ccataactgt tcctagtcaa
      301 cctgcaagcc ctgtcccagc tccaagctca gctccgactc aagatcctag agtggtagca
      361 agcgcttcgg ctagctcaac gagcacacaa gctcaagagc aagttgacaa gtctgaactt
      421 cgtgccttga gtcaagagtt agaccaacgc ttgaaagctt tggcaacagt atctgatccg
      481 aaaatcgatg caaccaaggc tgtcctccta gatgctcaaa aagctccgga agatagtgcc
      541 ttgacagagt aaggtctgca tactgcagta gagtctgtga aggctgggct gccttggact
      601 ctctcaaaga tgtgaaagca aatgctagcg acagcaagcc tgcacaggac aagaaggatg
      661 caaaacaagg aacggaagat agtaaggatt cagataagat gactgaaaca aactcagttc
      721 cggcaggagt gattgtggtc agtctacttg ccctcctagg cgtgattgcc ttctggctga
      781 ttcgccgtaa gaaagagtca gaaatccagc aattaagcac ggaattgatc aaggttctag
      841 gacagctaga tgcagaaaaa gcggataaaa aagtccttgc caaagcccaa aaccttctcc
      901 aagaaaccct tgatttcgtg aaagaagaaa atggctcagc agagacagaa actaaactag
      961 tagaggagct taaagcaatc cttgacaaac tcaagtaaaa catgatttat gaaatgtcag
     1021 acctaaaaga cattttcgtt cacaaaagca gcgatgagta atccttgtcg ttgctttttg
     1081 gctattttgg gggataagat ccgccttgac tagcaaaaga aaagattggt ccaatagtgc
     1141 ccgatacgat tttgcgtagc agaaagctta caaataaaat tgaatatagt aaaataggat
     1201 tagaattatt aagaaagttg gttctttatt ggaaacgata gtatttttaa tctctgtttt
     1261 tctagcaggt gttttatcct ttttttctcc ttgtattttt cctcttctgc cagtctatgc
     1321 tgggatttta ttggatgatc aagaaagtgc aaaaagcttt tctttgtttg ggagaaaggt
     1381 tctctggtca ggcttgattc gaacactttg ctttatcgct ggtatctctc tcattttctt
     1441 tattctaggc tttggtgctg gttactttgg tcatattctc tatgcaaatt ggtttcgata
     1501 tgtcatggga gctattatta tcattttggg tcttcaccag atggaaattt ttcatttgaa
     1561 gaaattagaa gttcaaaaaa gttttacctt taaaaaatca gattctaatc gttattggtc
     1621 agctttttta cttggtatta cctttagctt tggttggaca ccttgtattg gtccagtttt
     1681 aagttctgtt ttagcacttg cggcttctgg aggcaatggt gcttggcaag gagcgattta
     1741 tactctcatt tacactctgg gcatggccct tcctttcttg gtcttggcac tagcttcagg
     1801 tctagtcatg ccatatttta gtaaaatcaa gcgtcatatg atgctactaa agaaaattgg
     1861 tggtttcctc attgttttaa tgggaatttt gttactatta ggacaagtaa atgttctagc
     1921 tggaattttt gaataaagga ggacaaatga aaaaagtaat gtttgctggc ttaagtctct
     1981 tgtcattagt tgtattgatg gcctgtggtg aggaagaaac taaaaagact caagcagcac
     2041 aacagccaaa acaacaaacg actgtacaac aaatttctgt tggaaaagat gctccagact
     2101 ttacattgca atccatggat ggcaaagaag ttaagttatc tgattttaag ggtaaaaagg
     2161 tttacttgaa gttttgggct tcatggtgtg gtccatgcaa gaaaagtatg ccagagttga
     2221 tggaactagc ggcgaaacca gatcgtgatt tcgaaattct tactgtcatt gcaccaggaa
     2281 ttcaaggtga aaaaactgtt gagcaattcc cacaatggtt ccaggaacaa ggatataagg
     2341 atatcccagt tctttatgat accaaagcaa ccaccttcca agcttatcaa attcgaagca
     2401 ttcctacaga atatttaatt gatagccaag gaaagattgg aaagattcaa tttggtgcta
     2461 tcagtaatgc ggatgcagaa gcagcattta aagaaatgaa ctagaatcga taaaatctga
     2521 ttacaagatg tagtcagatt ttggtaactt ctaaaactaa cttccagttt cccacaacct
     2581 agcttttagt atgagaaaaa cgcgtgacat cagtggaaat ccgtcttaga ctaacttcca
     2641 ctggttttct ttttcttgat atataagggt tcaaaagcga aaagactcag aaaaagtgca
     2701 cgacaaatag ccctaaaaca gagtcgtctt agagtaactt ccagttttgg gagagagatg
     2761 gaagttactt tgagaagtta cggtagtcag atttttttag aaaaacattt tataaatatt
     2821 cacatatctc ctatatttat ggtaaaatag aattatcagt ttattttgga gtcaaagatg
     2881 aatatattta gaacaaagaa tgttagttta gataaaacag agatgcatag gcatttgaag
     2941 ttatgggatt tgattttgct gggtatcgga gccatggtag ggacaggcgt ctttacaatc
     3001 acaggtactg cagctgcaac acttgctggc ccagccctag tgatttcaat cgttatttct
     3061 gccttgtgtg tgggattatc agccctcttt tttgcagaat ttgcctcgcg agtacccgct
     3121 acaggaggtg cctatagtta cctctatgct atcttaggag aattccctgc ctggttggct
     3181 ggttggttaa ccatgatgga gttcatgaca gccatatcag gcgtagcttc gggttgggca
     3241 gcttatttta aaggcttgct ctctcaatac aggatagcct ttcctcaggc tttaaatggt
     3301 acctttaatc ctcaagcagg gacatttgtt gatttattgc ctattcttgt cttggtcttg
     3361 gtgacttcgc ttgttttact aaatgccaag gcagccttac gctttaattc gattctagtt
     3421 attttgaaat tttccgcttt agctctcttt gttttagtag gaatttggaa tattaagttt
     3481 gataattgga gcaattttgc tccttacggt tttggacaaa tctatggagc tagcactggt
     3541 attatggctg gtgcgtcctt gatgttcttc ggttttttgg gatttgaatc catctctatg
     3601 gctgtagatg aagtcaagac tcctcaaaaa aatattccta gagggattgt cttatcgctt
     3661 tctatcgtaa ccattctcta tgccttggtg acccttgttt tgactggtgt ggttcactat
     3721 agtcatttaa atgtcgatga tgccgttgcc tttgcccttc gtagtgttgg gattagttgg
     3781 gcagccaact atgtgtcatt agtggctatc ttgaccttga ttacagtttg tatttcgatg
     3841 acctatgccc tatcgcgtat gatttacagt ttagcacgtg acggcttagt gcctgctgcc
     3901 tttaaggaac tgacgaagac tagcaagata ccaaagaatg ctactatctt gacaggtcta
     3961 gcttcagcag tagcagcagg aatgttccca ctagccagta ttgcagcctt tttaaatatt
     4021 tgtaccttag cctacttgat catgttggct tatggtctga ttcgcttacg gaaagaaaaa
     4081 ggaatgccca aagctgggga atttaaaaca ccattggtac ctctgttacc aattttatcg
     4141 atcatcattt gtttatcctt catgttacag tataatatga atacctggat tgctttccta
     4201 gttgcgttgt tagtaggaag tattatttac ttcacttatg gctataagca ttctaccata
     4261 gaagaataaa gtgaaagtct attgagttgt tgacactcag cagattttta tatgtgaaag
     4321 aaatttcaaa ttttttctaa aaatatcttg acagattaaa ttttcaggag tagaatattt
     4381 actagttaat taaatggtta aggagttgtt catgaagaaa caaaatttat ttttagtcct
     4441 gttaagtgtc tttcttttgt gcttgggggc ttgtggtcaa aaggaaagtc agacaggaaa
     4501 ggggatgaaa attgtgacca gtttttatcc tatctacgct atggttaagg aagtatctgg
     4561 tgacttgaat gatgttcgga tgattcagtc aagtagtggg attcactcct ttgaaccttc
     4621 ggcaaatgat atcgcagcca tctatgatgc agatgtcttt gtttaccatt ctcatacact
     4681 cgaatcttgg gcaggaagtc tggatccaaa tctaaaaaaa tccaaagtga aggtcttaga
     4741 ggcttctgag ggaatgacct tggaacgtgt ccctggacta gaggatgtgg aagcagggga
     4801 tggagttgat gaaaaaacgc tctatgaccc tcacacatgg ctagatcctg aaaaagctgg
     4861 agaagaagcc caaattatcg ctgataaact ttcagaggtg gatagtgagc ataaagagac
     4921 ttatcaaaaa aatgcgcaag cctttatcaa aaaagctcag gaattgacta agaaattcca
     4981 accaaaattt gaaaaagcga ctcagaaaac atttgtaaca caacatacag ccttttctta
     5041 tctagcgaag agatttgggc ttaatcaact tggtattgca ggtatctctc ctgaacaaga
     5101 accaagtcca cgacaactaa cagaaattca ggaatttgtt aagacctata aggttaaaac
     5161 gatttttaca gaaagtaacg cttcttcaaa agtagctgaa actcttgtca aatcaacagg
     5221 tgtgggtctt aaaactctga atcctttaga gtcagaccca caaaatgaca agacctattt
     5281 agaaaatctt gaagaaaata tgagtattct agcagaagaa ttaaagtgag gaaagaatga
     5341 aaatcaataa aaaatatcta gcaggttcag tggcagtcct tgccctaagt gtttgttcct
     5401 atgaacttgg tcgtcaccaa gctggtcagg ttaagaaaga gtctaatcga gtttcttata
     5461 tagatggtga tcaggctggt caaaaggcag aaaatttgac accagatgaa gtcagtaaga
     5521 gagaggggat caacgccgaa caaattgtta tcaagattac ggatcaaggt tatgtgacct
     5581 ctcatggaga ccattatcat tactataatg gcaaggttcc ttatgatgcc atcatcagtg
     5641 aagaacttct catgaaagat ccgaattatc agttgaagga ttcagacatt gtcaatgaaa
     5701 tcaagggtgg ctatgtgatt aaggtagacg gaaaatacta tgtttacctt aaagatgcgg
     5761 cccatgcgga caatattcgg acaaaagaag agattaaacg tcagaagcag gaacgcagtc
     5821 ataatcataa ctcaagagca gataatgctg ttgctgcagc cagagcccaa ggacgttata
     5881 caacggatga tgggtatatc ttcaatgctt ctgatatcat tgaagatact ggtgatgctt
     5941 atatcgttcc tcacggcgac cattaccatt acattcctaa gagtgatttg tctgccagtg
     6001 aattagctgc tgcccaagcc tattggaatg ggaagcaggg atctcgtcct tcttcaagtt
     6061 ctagttataa tgcaaatcca gctcaaccaa gattgtcaga gaaccacaat ctgactgtca
     6121 ctccaactta tcatcaaaat caaggggaaa acatttcaag ccttttacgt gaattgtatg
     6181 ctaaaccctt atcagaacgc catgt
//
LOCUS       DAVLTT010000084         5989 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLTT010000084 DAVLTT010000000
VERSION     DAVLTT010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5989
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.084"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(<1..911)
                     /locus_tag="VYN15_001933"
     CDS             complement(<1..911)
                     /locus_tag="VYN15_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1453202.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QAAQKTENLTPDEVSKKEGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHV"
     gene            complement(1069..3519)
                     /gene="phtA"
                     /locus_tag="VYN15_001934"
     CDS             complement(1069..3519)
                     /gene="phtA"
                     /locus_tag="VYN15_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV1453203.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQQTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            complement(3773..5506)
                     /gene="ptsP"
                     /locus_tag="VYN15_001935"
     CDS             complement(3773..5506)
                     /gene="ptsP"
                     /locus_tag="VYN15_001935"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV1453204.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPASAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(5512..5775)
                     /locus_tag="VYN15_001936"
     CDS             complement(5512..5775)
                     /locus_tag="VYN15_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV1453205.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
BASE COUNT         1557 a         1250 c         1137 g         2045 t
ORIGIN      
        1 acatggcgtt gactcaaagg cagtttgtag agctgtttca agagactatc aatgtcatta
       61 ctttgacttg cttgactgtt agtgttgctg ttgttgcttg tgttagtatt tgtagttcct
      121 ggattgctta cagaaggtac ccagtttgtt cttggagtgt tatcgctatt ttgtcggcga
      181 taggttcttg aatttgacag atttccccga ccagatagga aggcttctgc agcagccaac
      241 tcgctagctg ataactcatt cttaggaatg taatggtaat ggtcgccgtg aggaacgata
      301 taagcatcac ccgtgtcctc aatgatatca gatgcattga agatataccc atcatctgtg
      361 gtgtagcgtc cctgtgaacg tgcaaaggct accgcaccat cgtttgctga agtccctcct
      421 tcacgatgct gactatgttc ttgtttttgc cgattgattt cttcttttgt acggacatta
      481 tccgcgtggg cagcatcctt aaggtaaaca tagtattttc catctacctt gataacataa
      541 ccacccttga tttcactgat aatatcctcg tcttttagct ggtagtttgg atccttcatc
      601 agcaattctt cactgatgat agcgtcataa ggaaccttcc cattgtaata atgatagtgg
      661 tcgccatgtg aagtgacata gccttggtct gttatcttga tgacgatttg ttcggcattg
      721 ataccttctt ttttactgac ctcatcagga gtcagattct ccgttttttg tgctgcttgt
      781 ttaccatcta tataggaaac acgattattt tcttttacag tttgagcttg atgcaaacct
      841 agttcataag cacagacact taaaacaagt gtagctactg acccagctag atatttttta
      901 ttgattttca ttctttcctc ttttctcaag tatatttgat tcactataaa gtaataaacc
      961 ggttaattaa ctagttaata gtttactctt tttaatattg cttgtcaaga attttacata
     1021 tatacataat aaaaatgaaa gcctctttat cgagactttc atttttcatt agtttatttt
     1081 ttccttactt acagatgaag gattacttcc ttttaacaac gcaagtaatt tttctgcttc
     1141 tgccatgata ctattgttat ccataatttg aagagtcaaa ttatttcgta aaccagctag
     1201 agtttctgtt gcattggctt tcagactaga atccgttact ttcgcaagca aaacttctgc
     1261 ttctttgagt tgggcttcta ctttttcagt ctctacttga gggacttctg gctcagcagg
     1321 tgtttcctct actggctctt catccgcttt gaagttctta tttggatctt cactgtggtc
     1381 tttcttgcct aacacatgct cactggcatt gccccatcca tcattagaat gtggacgttc
     1441 gtcagggtgt tctacgtagt acttaatcgt cgcaaacaaa tcttccaagg tatagccatt
     1501 tggagctttg tatgtgtgat catcaaacca agcaaattta atattatggt aatgatcctt
     1561 atgaggaata atcaaattac cgtttttaac ctcaactgta tgctcaacca tatatggaag
     1621 tcgaacgagt ggaattcgtt tttccccttt cacacgattg taaatagctg ctgcactatc
     1681 tccagttgga tttgctttaa catctgcgtc tggagatgga ggtaggatac ctttttcttt
     1741 agtataggct tgagctgcaa ctttttcctt atcagaaagg ctgtcttttc caatccagtg
     1801 actatggccc atatgaggcg ttacatatgc atctccttca tcactgatta tatcatgttc
     1861 atcaaaaatg taaccatctg acgttgtata cttatcagct aattgagcaa tacgaacttc
     1921 gtcttcagta tactcaattt gagaatttgg cttgccaagt cgctctggat gggtaattgg
     1981 tgctaggaat gccaataaat catctaccaa tttttcttta ttagtcgatt catcattcaa
     2041 gcgttctaat aatttgtcta aggcttggaa atcagaatta cgacccttat tttcaaacaa
     2101 ggctttatga gcctcagtta acagattata tgctttatca taaaattctt ggtcacgagg
     2161 agcaacattt tcttttttag cagttaaagt gtgtgaaaca ctctcttgtt ttgataactt
     2221 gctttcaaga tttttaacag tttcagatgg taaatctttc gcaaagacat aacgagagat
     2281 gcccttttct tcgaatacat atccttcccc aacttttcgt accagctgac taaccaaaga
     2341 agaatttgaa tctattttaa gatttggtgc aggttgcggg cctggactag gttccggagt
     2401 ctgttgtgga cttggttgtt ctggccttga atccggtacc caatggtttg aacgataacg
     2461 aaggggaata atacgagcga ttcgttcttc caattcagac atttgagagt aagggatgaa
     2521 gtggtaatga tctccgtgtg gcactgcaac acctctagct gttcgacttg tgatttgcgc
     2581 tgggtcgaaa ataaggccat cagattctac atggcgttga ctcaaaggca gtttgtagag
     2641 ctgtttcaag agactatcaa tgtcattact ttgacttgct tgactgttag tgttgctgtt
     2701 gttgcttgtg ttagtatttg tagttcctgg attgcttaca gaaggtaccc agtttgttct
     2761 tgaagtgtta tcgctatttt gtcggcgata ggttcttgaa tttgacagat ttccccgacc
     2821 agataggaag gcttctgcag cagctaactc gctagctgat aactcattct taggaatgta
     2881 atggtaatga tctccatgag gaacgatata agcatcacca gtatcctcta tgatatcaga
     2941 agcattaaag atataaccat catctgtagt atagcgtcct tgcgaacgtg ccaaggcaac
     3001 agcaccatcg tttcttggag tcccaccttc acgatgttga ctatgctctt gtttttgtcg
     3061 attgatttcc tcttttgtac ggacgttatc cgcgtgggca gcatccttaa ggtaaacata
     3121 gtattttcca tctaccttga taacataacc acccttgatt tcactgataa tatcctcgtc
     3181 ttttagctgg tagtttggat ccttcatcag caattcttca ctgatgatag cgtcataagg
     3241 aaccttccca ttgtaataat gatagtggtc gccatgtgaa gtgacatagc cttggtctgt
     3301 tatcttgatg acgatttgct cagcattgat tccttcacgc ttgctaacct catcaggagt
     3361 caaattctcc gttttttgcg tcgcttgttt tccatctata taggaaacac gattattttc
     3421 cttaaccgtt ctagcttgat acagtcccaa ctcgtaagaa caaacactta aaatcaaagc
     3481 tgccgcagaa ccaacaaggt atttcttatt aattttcatc gaaactctct ttctatttga
     3541 tatttctagt tgcaattcat ttctaaattg cagaaactcc tctctattac ttaactggtt
     3601 aatagtttac tcctaaatct ccaacttgtc aagaatttta tgaaccattt aagtattttt
     3661 tgttctgacc actacttttt caaggttgga ctttctataa gaaagatttt cttgaaaatt
     3721 ctttttaaaa tatcaaaaaa atccctgtaa ctgagttgca gggatttttc gattaatcaa
     3781 aattaacgta ttctttttga agttcaagaa cttcttccat tgttgagcat tctgtaaggg
     3841 cacggtttgc gtactcttcc atcttagctg tgtcgagttt cttcatcaag ctgcgtgtac
     3901 gaagtacaga tgttgctgac atagagaact catccaagcc cattccgaca agaagtggaa
     3961 cagcttgttg gtcaccagcc atctcaccac acataccagc ccatttacct tcagcgtgag
     4021 ctgctttgat cacattgtta atcaagcgta ggattgatgg gttgtatggt tggtaaaggt
     4081 atgaaacttg ttcgttcata cggtctgctg ccattgtata ttggatcaag tcatttgtac
     4141 caattgagaa gaagtcaact tctttagcaa attggtctgc aagcatagcc gatgcaggaa
     4201 tctcgatcat gataccaact tgaatgttat ccgcaactgc aacaccttca gcaagaaggt
     4261 ttgctttttc ttcatcaaag actgctttcg ctgcacggaa ttctttcaag agcgcaacca
     4321 ttgggaacat gatacgcaat tgaccgtgaa cagacgcacg aagaagagca cggatttgtg
     4381 tgcggaacat agcatctcca gtctcagaga tagagatacg aagagcacgg aatccaagga
     4441 atgggttcat ttcgtgaggc atatcgaagt aaggaagttc cttatctcca ccgatatcca
     4501 ttgtacgaac gacaacaggt ttaccgttca ttccttcaag aacagccttg tatgcttcat
     4561 actgctcatc ttcagttggg aagtcttgag aatccatgta caagaactct gtacggtaaa
     4621 gtccaacagc ttctgcaccg ttgttgttaa caccttcaac gtcttttgga gtaccaatat
     4681 tggcagccaa ctcgaagtgt ttaccgtcag cagtcactgt ttgagcatct ttcaaaagtg
     4741 cccattcagc tttttgtttc gcataggctt caccagctgc tttaaattct gccgcttgtt
     4801 catctgttgg gttgataatc acttctccag tgatcccgtt aacagcaagg atgtcaccgt
     4861 ctttaacgat ttcagtgatg ttgtttgtac ctaatacagc agcaatttca agtgtacgtg
     4921 ccatgatagc tgagtggctt gtacgtccac caatgttggt tacaaaagct tttacaaagt
     4981 ttttgtccaa ttgagctgta tctgaaggag tcaagtcatg cgcaatcaca atcacttctt
     5041 cattgataga agctgggttt ggcaattttt taccaagaag gtttgccaat acacgttttg
     5101 tcacgtcgcg gatatccgct gcgcgttctt gcatgtatgg gttgtcttcc atgccttcaa
     5161 agatagtgat aaacatatct gtaacttctt tcagacctgc ttctgcattc actttcttcg
     5221 cacggatagt ttccttgatt tggctgatca tttctgggtc agcaagaacc attaagtgag
     5281 catcaaaaac ttgagctgct tcttcaccga gcgtacctac tgctttctcg cgaataacag
     5341 aaagctcgtc ttgtgatgcc tgtagagcgg catcaaggcg agcttcttct gcgtttgtat
     5401 cttcgactgt aatagtctca aatgacaaat ccggctgaac gagtagatat gcttttgcaa
     5461 ctgcaacacc gtcagatgct gcgattcctt taagcatttc tgtcatttcc cttatgccaa
     5521 tccttctttt tccattgttt ctgagattgc agcgatagcg tcatctgcat ctgcaccttc
     5581 agctgagata gttacgtcag caccttgacc aacaccaaga ctcataacac ccataattga
     5641 tttaaggtta actgatttac ctttgtactc aagagtgata tctgaagcaa atttgctagc
     5701 agtttgtacc aacaatgttg ctggacgtgc gtgaatacct gtttctgcca ctacgtggaa
     5761 atctttagaa gccatagttt gactctcctt ttgttctttc tttttttgag ttatatgtga
     5821 taacccttac aatttagtat tataccatct tctaggattt ttttcaagca ttttctggat
     5881 tttccttcaa tttcctttca gataacttgc tgaaaatctt ctatcctaga taacaaaaca
     5941 caggatatag tttcttcaaa aacaatttat aggataatca ttgctattt
//
LOCUS       DAVLTT010000085         5968 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLTT010000085 DAVLTT010000000
VERSION     DAVLTT010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5968
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.085"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            25..1725
                     /locus_tag="VYN15_001937"
     CDS             25..1725
                     /locus_tag="VYN15_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV1453206.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGADTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            1718..2194
                     /gene="ilvN"
                     /locus_tag="VYN15_001938"
     CDS             1718..2194
                     /gene="ilvN"
                     /locus_tag="VYN15_001938"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV1453207.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            2260..3282
                     /gene="ilvC"
                     /locus_tag="VYN15_001939"
     CDS             2260..3282
                     /gene="ilvC"
                     /locus_tag="VYN15_001939"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1453208.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            3389..3625
                     /locus_tag="VYN15_001940"
     CDS             3389..3625
                     /locus_tag="VYN15_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453209.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            3810..3950
                     /locus_tag="VYN15_001941"
                     /pseudo
     CDS             3810..3950
                     /locus_tag="VYN15_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
     gene            4000..5250
                     /gene="ilvA"
                     /locus_tag="VYN15_001942"
     CDS             4000..5250
                     /gene="ilvA"
                     /locus_tag="VYN15_001942"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV1453210.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
BASE COUNT         1834 a         1011 c         1371 g         1752 t
ORIGIN      
        1 tttaagagga aagaaagggg aacaatggag aaaatcagtt tagaatctcc taagacgggg
       61 tcggacctag ttttggaaac acttcgtgat ttaggagctg ataccatctt tggttatcct
      121 ggtggtgcgg ttttgccttt ttatgatgcg atatataatt ttaaaggcat tcgccacatt
      181 ctagggcgcc atgagcaagg ttgtttgcat gaagctgaag gttatgccaa atcaactgga
      241 aagttgggtg ttgccgtcgt cactagtgga ccaggagcaa caaatgccat tacagggatt
      301 gcggatgcta tgagcgatag cgttcccctt ttggtcttta caggtcaggt ggcgcgagca
      361 gggattggga aggatgcctt tcaggaggca gacatcgtag gaattaccat gccaatcact
      421 aagtacaatt accaagttcg tgagacagct gatattccgc gtatcattac ggaagctgtc
      481 catatcgcaa ctacaggccg tccagggcca gttgtaattg acctaccaaa agacatatct
      541 gctttagaaa cagatttcat ttattcacca gaagtgaatt taccaagtta tcagccgact
      601 cttgagccga atgatatgca aatcaagaaa atcttgaagc aattgtccaa ggctaaaaag
      661 ccagtcttgt tagctggtgg tggaattagt tatgctgagg ctgctacgga actaaatgaa
      721 tttgcagaac gctatcaaat tccagtggta accagtcttt tgggacaagg aacgattgca
      781 acgagtcacc cactctttct tggaatggga ggcatgcacg ggtcattcgc agcaaatatt
      841 gccatgacgg aagcggactt tatgattagt attggttctc gtttcgatga ccgtttgacg
      901 gggaatccta agactttcgc taagaatgct aaggttgccc acattgatat tgacccagct
      961 gagattggca agattatcag tgcagacatt cctgtagttg gagatgctaa gaaggccttg
     1021 caaatgttgc tagcagaacc aacagttcac aacaatactg aaaagtggat tgagaaagtc
     1081 actaaagaca agaatcgtgt tcgttcttat gacaagaaag agcgtgtggt tcaaccgcaa
     1141 gcagttattg aacgaattgg tgaattgacg aatggagatg ccattgtggt aacagacgtt
     1201 ggtcaacacc aaatgtggac agctcagtat tatccctacc aaaatgaacg tcagttagtg
     1261 acttcaggtg gtttgggaac aatgggcttt ggaattccag cagcaatcgg tgctaaaatt
     1321 gctaacccag ataaggaagt agtcttgttt gttggggatg gtggtttcca aatgaccaac
     1381 caggagttgg ctattttgaa tatttacaag gtgccaatca aggtggttat gctgaacaat
     1441 cattcacttg gaatggttcg ccagtggcag gaatccttct atgaaggcag aacatcagag
     1501 tcggtctttg atacccttcc tgatttccaa ttgatggcgc aggcttatgg tattaaaaac
     1561 tataagtttg acaatcctga gaccttggct caagaccttg aagtcatcac tgaggatgtt
     1621 cctatgctaa ttgaggtaga tatttctcgt aaggaacagg tgttaccaat ggtaccagct
     1681 ggtaagagta atcatgagat gttgggggtg cagttccatg cgtagaatgt taacagcaaa
     1741 actacaaaat cgttcaggag tcctcaatcg ctttacaggt gtcctatctc gtcgtcaggt
     1801 taatattgaa agcatctctg ttggagcaac agaagatccg aatgtatcgc gtatcactat
     1861 tattattgat gttgcttctc atgatgaagt ggagcaaatc atcaaacagc tcaatcgtca
     1921 gattgatgtg attcgcattc gagatattac agacaagcct catttggagc gcgaggtgat
     1981 tttggttaag atgtcagcgc cagctgagaa gagagctgag attttagcga ttattcaacc
     2041 tttccgtgca acagtggtag acgtagcgcc aagctcgatt accattcaga tgacgggaaa
     2101 tgcagaaaag agcgaagccc tattgagagt cattcgccca tacggtattc gcaatattgc
     2161 tcgaacgggt gcaactggat ttacccgcga ttaaaaatcc aacttaaatt tattaaacca
     2221 gcctaaaagg caataaataa tagaaaagag agaaaagcta tgacagttca aatggaatat
     2281 gaaaaagatg ttaaagtagc agcacttgac ggtaaaaaaa tcgccgttat cggttatggt
     2341 tcacaagggc atgcgcatgc tcaaaacttg cgtgattcag gtcgtgacgt tattataggt
     2401 gtacgtccag gtaaatcttt tgataaagca aaagaagatg gatttgatac ttacacagta
     2461 gcagaagcta ctaagttggc tgatgttatc atgatcttgg cgccagacga aattcaacaa
     2521 gaattgtacg aagcagaaat cgctccaaac ttggaagctg gaaacgcagt tggatttgcc
     2581 catggtttca acatccactt tgaatttatc aaagttcctg cggatgtaga tgtcttcatg
     2641 tgtgctccta aaggaccagg acacttggta cgtcgtactt acgaagaagg atttggtgtt
     2701 ccagctcttt atgcagtata ccaagatgca acaggaaatg ctaaaaacat tgctatggac
     2761 tggtgtaaag gtgttggagc ggctcgtgta ggtcttcttg aaacaactta caaagaagaa
     2821 actgaagaag atttgtttgg tgaacaagct gtactttgtg gtggtttgac tgcccttatc
     2881 gaagcaggtt tcgaagtctt gacagaagca ggttacgctc cagaattggc ttactttgaa
     2941 gttcttcacg aaatgaaatt gatcgttgac ttgatctacg aaggtggatt caagaaaatg
     3001 cgtcaatcta tttcaaacac tgctgaatac ggtgactatg tatcaggtcc acgtgtaatc
     3061 actgaacaag ttaaagaaaa tatgaaggct gtcttggcag acatccaaaa tggtaaattt
     3121 gcaaatgact ttgtaaatga ctataaagct ggacgtccaa aattgactgc ttaccgtgaa
     3181 caagcagcta accttgaaat tgaaaaagtt ggtgcagaat tgcgtaaagc aatgccattc
     3241 gttggtaaaa acgacgatga tgcattcaaa atctataact aattagaaat atatagcgct
     3301 ggagatgatt ttatgaaaaa gattatgaga aaaattgcat cgttattatt ggttctagtt
     3361 gtataatgta attacaccgt cggtaatagt gctagcagac caaaataaag cagattggtc
     3421 gtatgatgaa aatgctgtaa ttaacattta tgatgatgct aattttgaag atggtaggtt
     3481 gcatatgacc tttgaacaat tcttcaaatt ggcacaaata gctagagaag aaggtcttga
     3541 aattcattct ccgtttgaga gagctggtgc gactaaatct gctcgttata tagcgaaatg
     3601 gattttgaga aataaaaaac attaacaaat atagttggta aatcattagg acctaaatca
     3661 gctgttagat tcggagaagc tttatcctat attgaaggtc ctcttcgcag aataaatgag
     3721 acgatagatg gcggtttata tcaaatagag caaattattg catctggatt gaaagaatcg
     3781 ggtttaaatg actggactgc gaaaactttc gtaatgatag tgaagaaagt ttggtagaat
     3841 ggttatatga ttggatttcc acaaatcgtt atgaacttcc taaagagttt tcgattcgta
     3901 tggctcataa ataccatgaa agtgttactg aagttttcgg agatgaataa ctaaaaaaca
     3961 gtcattagtg actgtttttt atagaaaaag aggttttata tgttaagttc aaaagatata
     4021 atcaaggctc acaaggtctt gaacggtgtg gttgtgaata ctccactgga ttacgatcat
     4081 tatttatcgg agaagtatgg tgctaagatt tatttgaaaa aagaaaatgc ccagcgtgtt
     4141 cgctccttta aaattcgtgg tgcctattat gccatttccc agctcagcaa ggaagaacgt
     4201 gaacgtgggg tagtctgcgc ttctgcggga aatcatgcgc agggagtagc ctatacttgt
     4261 aatgaaatga aaattcctgc tactatcttt atgcccatta ctacgccaca acaaaagatt
     4321 ggtcaggttc gcttttttgg tggggatttt gtaactatta aactagttgg agataccttt
     4381 gatgcctcag ccaaagcagc tcaagaattt acagtctctg aaaatcgtac ctttattgat
     4441 ccttttgatg atgctcatgt tcaagcaggt caaggaacag ttgcttatga gattttagaa
     4501 gaagctcgaa aagaatcgat tgattttgat gctgtcttgg ttcctgttgg tggtggcggt
     4561 ctcattgccg gggtttctac ctatatcaag gaaacaagtc cagagattga ggttatcgga
     4621 gtagaggcga atggagcgcg ttccatgaaa gctgcctttg aggctggagg tccagtcaaa
     4681 ctcaaggaaa ttgataaatt tgcggatggg attgctgtgc aaaaggtagg tcagttgacc
     4741 tatgaagcaa ctcgtcaaca tattcaaact ttggtaggtg tcgatgaggg attgatttct
     4801 gaaaccttga ttgaccttta ctctaagcaa gggatagtcg cagagcctgc tggagcggct
     4861 agtatcgcct ctttagaggt tttagctgaa tatattaagg ggaaaaccat ttgttgtatc
     4921 atttctggag gaaataatga tatcaaccgt atgccagaaa tggaagagcg tgccttgatt
     4981 tatgatggta tcaaacatta ctttgtggtc aatttcccac aacgtccagg agctttgcgt
     5041 gagtttgtaa atgatatcct ggggccaaat gatgatatca cacgttttga gtatatcaaa
     5101 cgagctagca agggaacagg cccagtattg attgggatcg ctttagcaga taagcatgat
     5161 tatgcaggtt tgatccgtag aatggaaggt tttgatccag cttatattaa cttaaatggt
     5221 aatgaaacgc tttataatat gcttgtctga ggactaataa aaaaatatca tattatttgt
     5281 acaactgatg tatatgtgct ataatgaaga tgaagaaagg ggacgattcc tatggtttta
     5341 gaaaacttat cgtgcaattc ttacttctgt tcattatagc acttatgatg tttggctcag
     5401 atttccatcc ttcattttga tttcctatct attgacaagc atagtcacac tgtctttaat
     5461 actcttcgaa aatctcttca aaccacgtta gctctatctg caacctcaaa acagtgtttt
     5521 gagcaacttg cggctagctt cctagtttgc tctttgattt tcattgagta taaggtatga
     5581 tttgatttct ttttgttgac aaatatacca tattaaaaag atatataagt aattaactga
     5641 gcttatctgt cttgtcatct ctattaagga tggtttagat aatcgggtgt ctgcttctag
     5701 gctagcacct caatatccaa aggagtgatg aatttgaaag atataaggaa tacctatctc
     5761 tcagatgatt tattgaggaa gaaagatagg agtttttgag ctagtgaagg cttggatttc
     5821 taaaggttag aactatcatc ttcagttctt aaatcgaaga aataagctat cttacggaaa
     5881 tagagaagca ttttttaaga acttgaataa tttcgcacct taagagggta ataatacagt
     5941 atttttatta gcaaatattt atggtgta
//
LOCUS       DAVLTT010000086         5950 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLTT010000086 DAVLTT010000000
VERSION     DAVLTT010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5950
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.086"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(<1..696)
                     /locus_tag="VYN15_001943"
     CDS             complement(<1..696)
                     /locus_tag="VYN15_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV1453211.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEY"
     gene            complement(698..1255)
                     /locus_tag="VYN15_001944"
     CDS             complement(698..1255)
                     /locus_tag="VYN15_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1453212.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAACALIDLAFKELGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            complement(1242..1691)
                     /locus_tag="VYN15_001945"
     CDS             complement(1242..1691)
                     /locus_tag="VYN15_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HEV1453213.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDARPLVLDCRVDRIVEEDGICHIFAKILERLVVPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(2104..2499)
                     /locus_tag="VYN15_001946"
     CDS             complement(2104..2499)
                     /locus_tag="VYN15_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1453214.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLNLKGIGPATIKKLKENGIKFK"
     gene            complement(2595..2849)
                     /locus_tag="VYN15_001947"
     CDS             complement(2595..2849)
                     /locus_tag="VYN15_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV1453215.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(2859..4193)
                     /locus_tag="VYN15_001948"
     CDS             complement(2859..4193)
                     /locus_tag="VYN15_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV1453216.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAKG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(4193..4426)
                     /locus_tag="VYN15_001949"
     CDS             complement(4193..4426)
                     /locus_tag="VYN15_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV1453217.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            4457..4531
                     /locus_tag="VYN15_001950"
                     /pseudo
     CDS             4457..4531
                     /locus_tag="VYN15_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4886..5068)
                     /locus_tag="VYN15_001951"
     CDS             complement(4886..5068)
                     /locus_tag="VYN15_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453218.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(5070..5849)
                     /locus_tag="VYN15_001952"
     CDS             complement(5070..5849)
                     /locus_tag="VYN15_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453219.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRVGSITIAK
                     QVMKIVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT         1743 a         1347 c         1029 g         1831 t
ORIGIN      
        1 gtattctttc actagagcta tagcgtcaat cttagatgtt tcttggttta gttttatcaa
       61 ctcccctttc aattttttcc atttaaagtt ggaatttaaa agataatcta aatcaatata
      121 gaaatctatt ataacagtct catcatctgg gctaacagct tttacctcat ttattggtaa
      181 gtcagtatgt tgcgaataat ttctcaaaga atggcaaaat cgataagcaa aattggtatc
      241 atactgatag cttgcaaaac catgtataca atcaaactcc tcactatctt tggaatattt
      301 ttgtttaatt tggttttcgt taaaatcgac aaacaatttt ccactggata ataaatgaat
      361 catgaaacga tttacatctg cctcttcaat ttctaattcc tttgactcaa gtttattttt
      421 aatacttaaa aaatccgaga catctgaaat aaacaattcg aacatattct tgattttttg
      481 aaaattcttt tgaatctcaa aaatttggtc cgagactgac attatttcct tggttggttc
      541 aatatcagag atgacaatac gtttttcatt gttgttaatt tctaaataag ctaatcgctc
      601 gataatatca ctatcattta attcagcata ctcaacatca atttggcgta actgcttctc
      661 agatagagag cttacttcct cttttacatc gctcatctta ttcctcccac tcgctcttca
      721 gcaagccata tatcagactg tcacagcggt ttccttgaac atcctttcgg tctcttatgc
      781 gagcttcgag ggtaaagcca agcttttccg cgactcgttt actttgaagg ttatatccaa
      841 agcaagttag ttcaatcttg tgaagaccaa gttctttaaa agctagatca atcaaggcac
      901 acgctgcttc tggaacataa cctcgccccc aatagtctgg gtgtaaggta tagccgattt
      961 ccagcacatc atcttcatgg cgatggttga aatcgacaga gccaacgatc ttatccgttc
     1021 ctttgacgac aatcccgtag cctgctggga gattttcctt ttgattacgc tccggaagaa
     1081 tgtgctccag ataataaatc tcatcttcca aggtcttgac tggaggaaaa cctgctggat
     1141 aggcgacctc tggcaaacta gcatagtcaa agatatcctc agcatccgcc acagtacgga
     1201 ctcgtaaaac gagacgttct gtttcgattt tatctggcag ctcagttctt gccatccttc
     1261 ttcctcgctt ttttgatgaa actgcccttc atatctacac gcttgtccag atagcgataa
     1321 acgcgctgat atccatctcc catgaaatag gttggggcaa acagttgatt tttaaaatgt
     1381 cccttttcat ccaggagttc tggaacaaca agtcgctcaa gaatcttggc aaagatgtgg
     1441 caaataccgt cttcctcaac aatcctatct acccgacaat ctaaaacaag tggacgggcg
     1501 tctaaaatag gagtctgagt tcgttcagaa atttcataat gcactcccaa acgttccaat
     1561 ttctcctgat gactgataaa accagcctgc tccatcgcaa gcatagaagt ttcatcagaa
     1621 atattcacag taaatttttg atactgtttg atctgctctg cggcattctc tctcgcaacg
     1681 actccaatca caacccaatc tcctagacta taagaggaac tacaggtcgt gatgttatag
     1741 ccaaaattct aatcttgata tcctaaaata aaaacaggaa aaccataata tagtttactt
     1801 gtgttaaaag attgcttcat aacaaccccc tttgactaag acgtaaaaga aaagccctgc
     1861 catctacatg acagggacga atgtgtttat ccgcggtacc acccaatttc gggcagttgc
     1921 ccgcaactct cgtctttaaa gcaaaaagac acttttattt caatttttca tccattagca
     1981 accagttttg acacatttgt ggacttctca gcgccgccac tttctgtaaa atgtgggatt
     2041 caaaacacct ctaatggctc tattgtagca agattttttc ggaaatgcaa ggctcaagaa
     2101 aaattacttg aacttgatgc cattttcttt caatttcttg atggtagctg ggccgattcc
     2161 tttcaagtta aggagttctt tttcagtcca gtttttgaaa tctgaagcag acttgattcc
     2221 ttcatcatag aaagtcttgg cacgatcaag tggaagtcca cccaagtttg ctgcaaaatc
     2281 ttctacagaa ttagctactt tttgagcttg ctctttggta gcttctactg cttgttcaac
     2341 ttttttagaa acagccttac cagctgcgct tgctgactgt tctgcacgct tcacgacttt
     2401 ttttgtctca tctacaacct tagtcacagt acttgaaaag gcacctgcgc gacggaggcc
     2461 atttcgtaat tgttttttac gattgagttt ctttgacatg ataaaatcct ttcaataaaa
     2521 aatccctgct ctgacaagga tttaacataa acattctatc aagattttag tgaaaaatca
     2581 agaatctttc tcgtttaata atttcgctca ccaaacaagc cttctggcaa atcatggaat
     2641 cccttgccta ctttgaagtt ttcaaactta ccaagcaaga actgataagc atccaaacga
     2701 ctctcgtagc gaatcatggc atctttggca cgctcgtcct ggtcttcttc gtaaactttt
     2761 tgactttcct tgtgcgccat gtcgttaatc atgatttggg tattgaccca agcttcaaat
     2821 tccttcataa attcttgttc gtaactcatt ttttctcctt attctaatcc acggaaatag
     2881 tccgtatcaa tctcacggta gggctggata tcctgaacgt attccagtac accttggaat
     2941 tctccgtttt catcgtgtac tgcagcatag gtgatgtgga caaactttcc tcgcgactca
     3001 gacttgaacc acatttcata cttgtccttg gtcccctcac gaagtccctt catgatagcc
     3061 ttgaccttgt ccaaatactt aggcggatga cagagttcga cattgcgccc gacttgggac
     3121 ggcgtccgtt tgaaaatcat ctcatcagct ggcgtattgt cattgtaata ctggaaaata
     3181 tcttctttat tgacaaaggt aatctccata gggagatgat tgaggatgag attggcctgc
     3241 tcgactgaaa gatagccatt accaaaagcc tgttgactat ggcggtccag cacagcttcc
     3301 ttttccttag gggtaaaggt aatggtaaaa tggccttctg gcgtatctat gacttgttga
     3361 acttgacctt ttgccgtatc tagttgtaca ggctcctctg caatcttttc ctcaataaag
     3421 atctgtcgtt ctggcaccca tttctctgac ggacggatga tggcatagcc ataggcatca
     3481 ctctcctccg caatctgaag ccagtcatcc tgagtaaaag actcaaggag aatcatgagc
     3541 aggatggact cttccttgaa aatcatactt tcaaactctg tcgcaaaagc ttcaaaagct
     3601 tcctttacac tgctaattga cacttctggt agtgacttgg ctgtcgttag agctgtttga
     3661 aagagttccc taatctgatc atccactccc cacataactt tgggaggtga atcgtgtcca
     3721 tagcgctcca tgataggaaa gaagagttct tccttacgtt ggtaatggat gtcaaattga
     3781 cccacaagtc ccatctgacg caccaaaccc ttacgcatct ccgccagcat ttcctcgtct
     3841 tccatagact cataggtatc taacaatcta cgaatgcgaa tcaaggccgc acggagagcc
     3901 agattttctt ctttgaagac acgaactggg tgacctggat gctcagtatc tgaaacttcg
     3961 acacctttga tagcattttt aaaaagattg gcatggacat cacagagttc cataacatct
     4021 tcaaaagtga cgcccgaatc cgagttcatc agctcgtgct ccataaggga aatctcgatg
     4081 gctgacacgc ccgtaaaggt cgcatcaaag cgatcttgaa ccgactcagg agaggcgcca
     4141 ttgtgcaatt ctaacaaaat atcccgtagg atatgaatcc gttcatctgt cattagtcta
     4201 atccaatcac ttcgtagcca ttcgcttcca gtgtgcgtac aatcttgtcc ataggagttc
     4261 ctgctagctt agaaccctgt ttaagtgata ctttacgacc aactgtattg cgcattaagg
     4321 gattggcaag gggtttaaaa cccaactcca ctagaatttc caagacttct ggatgcttgt
     4381 ccaccacttc tgcaacagga attgacacat cgatgatatt gtccatgacg acctccattg
     4441 tatgttctaa tactcaatga aaatcaaaga gcaaactagg aagctagccg caggttgctc
     4501 aaaacagtgt tttgaggttg tagatagaac tgacgaagtc agctcaaaac accgttttga
     4561 ggttgtggat agaactgacg aagtcagtaa catatatact gcaaggtgaa gctgacgtgg
     4621 tttgaagaga ttttcgaaga gtataaaatg attttactgc ttatattata ccatatggaa
     4681 agagaataaa aaactagcag tggagttcct gctagttctc tgcaacttgg attaccatct
     4741 agataagttt aaagagccaa tccaatatct taaacactat cttgtaaaac agcaattgga
     4801 ctgcaaaaga gatgatcatc caaaagaatt tcacaatccc aataatcggt ttgataaaaa
     4861 gaatagcaag aagaccaaaa aaatttcatt ctctctcctc tggcttaatg agccaccgag
     4921 ccgtatccat taacttgtcg gcaataaaaa gtttccccag accaacaacg acatggtcag
     4981 ctttctttat cgttttcatc acttttacac cttgcacggt caaaaagtaa ttaccataaa
     5041 ttttagcaaa agctttgata ggattcatat tactctcctt tgatgatttc agcctctttt
     5101 cggattgttt caacatcttc ttgatattga acttcactat agttgactag cttggataat
     5161 tctttctgca agctttcccc cattggtttc atagttgcaa aggttaaacc acctgaaatg
     5221 ataccaccca agataggaat aaatttcccc attcctttgg ccaaccctcc cttggtaaga
     5281 ttcacaccaa atatttttaa gacttttttc aaaatagggt accaaagcgt ctttgttaaa
     5341 gctttattag gcactatttt cattacctgt ttggcaattg ttatactacc aacacgtagc
     5401 aaagcagcgg ttccattcac ccctaacatt acgcctagat aaagcaagag ggtattttga
     5461 gcatcttcac tcaactcctc tcgtgaagcc caaagatcct cataaccata aatataacct
     5521 aattcttgag ccaatttcag agagaaagca taaaattgag ccacatcagc tggaatggta
     5581 attgccatag caagccctcc aggtaatcct gccaaaacag aagtcccact cgctaataat
     5641 acattgtccc gaatacaagc attagctaca cgatctaata tttcttgaga tagaagagtc
     5701 gttgtacctt gttccaataa ggtaggaata tcttttggat ccaattcttt ggaaaactta
     5761 tccactaaaa atttcgaacg atcaacctta acaacaggta gtttcaccac ttgttgcaat
     5821 acttgcatag ctaagtcttg ttcagccata tacaaactcc ttatttcttt tttacacctt
     5881 atcatattat atttcctaca aaaaaagcat tttctaatta gataacatta aaaaatacag
     5941 aacccctttt
//
LOCUS       DAVLTT010000087         5871 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLTT010000087 DAVLTT010000000
VERSION     DAVLTT010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5871
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.087"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            105..584
                     /locus_tag="VYN15_001953"
     CDS             105..584
                     /locus_tag="VYN15_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1453220.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRKYDKEPYEEVGELSHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            678..749
                     /locus_tag="VYN15_001954"
     tRNA            678..749
                     /locus_tag="VYN15_001954"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:711..713,aa:Glu,seq:ttc)
     gene            1001..2546
                     /locus_tag="VYN15_001955"
     rRNA            1001..2546
                     /locus_tag="VYN15_001955"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2598..2670
                     /locus_tag="VYN15_001956"
     tRNA            2598..2670
                     /locus_tag="VYN15_001956"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2631..2633,aa:Ala,seq:tgc)
     gene            2795..5696
                     /locus_tag="VYN15_001957"
     rRNA            2795..5696
                     /locus_tag="VYN15_001957"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5773..>5871
                     /gene="rrf"
                     /locus_tag="VYN15_001958"
     rRNA            5773..>5871
                     /gene="rrf"
                     /locus_tag="VYN15_001958"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1728 a         1135 c         1677 g         1331 t
ORIGIN      
        1 gcctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtgtataagt gtagaaatga atattacctt catttatggg
      181 aattatcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg taaatacgat aaagaaccct
      361 atgaagaagt gggtgagctc agtcatcgta taagtgaggg ggggctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgtgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ctaggaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa agactgtata atagtaagag
      661 ttgaaaataa caactcaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg
      721 taacacgggt tcgaatcccg tacggactat ggtatgttgc ggttggaaca cttgatgaaa
      781 aaaagtttaa aaaaacttaa aaatcttcaa aaaagtgttg acaagtgaaa gtggctgtga
      841 tatactaata tagttgtcgc ttgagagaag caagtgacaa agacctttga aaactgaaca
      901 agacgaacca atgtgcaggg cgctacaaca taagttgtag tactgaacaa tgaaaaaaca
      961 ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga gtttgatcct
     1021 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gaaggaggag
     1081 cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct gcctggtagt
     1141 gggggataac tattggaaac gatagctaat accgcataag agtggatgtt gcatgacatt
     1201 tgcttaaaag gtgcacttgc atcactacca gatggacctg cgttgtatta gctagttggt
     1261 ggggtaaggg ctcaccaagg cgacgataca tagccgacct gagagggtga tcggccacac
     1321 tgggactgag acacggccca gactcctacg ggaggcagca gtagggaatc ttcggcaatg
     1381 gacggaagtc tgaccgagca acgccgcgtg agtgaagaag gttttcggat cgtaaagctc
     1441 tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac actgtgacgg tatcttacca
     1501 gaaagggacg gctaactacg tgccagcagc cgcggtaata cgtaggtccc gagcgttgtc
     1561 cggatttatt gggcgtaaag cgagcgcagg cggttagata agtctgaagt taaaggctgt
     1621 ggcttaacca tagtaggctt tggaaactgt ttaacttgag tgcaagaggg gagagtggaa
     1681 ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccggtggc gaaagcggct
     1741 ctctggcttg taactgacgc tgaggctcga aagcgtgggg agcaaacagg attagatacc
     1801 ctggtagtcc acgctgtaaa cgatgagtgc taggtgttag accctttccg gggtttagtg
     1861 ccgtagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt gaaactcaaa
     1921 ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa
     1981 gaaccttacc aggtcttgac atccctctga ccgctctaga gatagagttt tccttcggga
     2041 cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt
     2101 cccgcaacga gcgcaacccc tattgttagt tgccatcatt tagttgggca ctctagcgag
     2161 actgccggta ataaaccgga ggaaggtggg gatgacgtca aatcatcatg ccccttatga
     2221 cctgggctac acacgtgcta caatggctgg tacaacgagt cgcaagccgg tgacggcaag
     2281 ctaatctctt aaagccagtc tcagttcgga ttgtaggctg caactcgcct acatgaagtc
     2341 ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat acgttcccgg gccttgtaca
     2401 caccgcccgt cacaccacga gagtttgtaa cacccgaagt cggtgaggta accgtaagga
     2461 gccagccgcc taaggtggga tagatgattg gggtgaagtc gtaacaaggt agccgtatcg
     2521 gaaggtgcgg ctggatcacc tcctttctaa ggataaggaa ctgcgcattg gtcttgttta
     2581 gtcttgagag gtcttgtggg gccttagctc agctgggaga gcgcctgctt tgcacgcagg
     2641 aggtcagcgg ttcgatcccg ctaggctcca ttggtgagag atcaccaagt aatgcacatt
     2701 gaaaattgaa tatctatatc aaatagtaac aagaaaataa accgaaaacg ctgtagtatt
     2761 aataagagtt tatgactgaa aggtcagaaa ataaggttaa gttaataagg gcgcacggtg
     2821 gatgccttgg cactaggagc cgacgaagga cgtgacaaac gacgatatgc cttgggtagc
     2881 tgtaagtaag cgatgatcca gggatttccg aatgggggaa cccaacaggt aatacctgtt
     2941 acccacatct gttaaggatg tgaggaggaa gacgcagtga actgaaacat ctaagtagct
     3001 gcaggaagag aaagcaaaag cgattgcctt agtagcggcg agcgaaacgg cagaagggca
     3061 aaccgaagag tttactcttc ggggttgtag gactgcaatg tggactcaaa gattatagaa
     3121 gaatgatttg ggaagatcag ccaaagagag taatagcctc gtatttaaaa tagtctttgt
     3181 acttagcagt atcctgagta cggcgggaca cgtgaaatcc cgtcggaatc tgggaggacc
     3241 atctcccaac cctaaatact ccctagtgac cgatagtgaa ccagtaccgt gagggaaagg
     3301 tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct acaacaagtt
     3361 cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag ttacgttatg
     3421 atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtctgaat agggcgcctt
     3481 agtatcatga cgtagacccg aaaccatgtg acctacccat gagcaggttg aaggtgcggt
     3541 aagacgcact ggaggaccga accagggcac gttgaaaagt gcttggatga cttgtgggta
     3601 gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag ctttagggct
     3661 agcgtcgaca ttagagattc ttggaggtag agcactgttt gggtgagggg tccatcccgg
     3721 attaccaatc tcagataaac tccgaatgcc aatgaattat ggtcggcagt cagactgcga
     3781 gtgctaagat ccgtagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
     3841 attgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttag cttagaagca
     3901 gctattcatt caaagagtgc gtaatagctc actagtcgag tgaccctgcg ccgaaaatgt
     3961 accggggcta aaacaattta ccgaagctgt ggataccttt ataggtatgg taggagagcg
     4021 ttctatgtgt gatgaaggta taccgtgagg agtgctggaa cgcatagaag tgagaatgcc
     4081 ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg taagactaag gtttccaggg
     4141 gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgaaagg tgtatccgat
     4201 ggacaacagg ttgatattcc tgtactagag tatgtagtga tggagggacg cagtaggcta
     4261 actaaagcag acgattggaa gagtctgtct aagcagtgag gtgtgaattg agtcaaatgc
     4321 ttaattctat aacattgagc tgtgatgggg agcgaagttt agtagcgaag ttagtgacgt
     4381 cacactgcca agaaaagctt ctagcgttta aacatactct acccgtaccg caaaccgaca
     4441 caggtagtcg aggcgagtag cctcaggtga gcgagagaac tctcgttaag gaactcggca
     4501 aaatgacccc gtaacttcgg gagaaggggt gctgacttaa agtcagccgc agtgaatagg
     4561 cccaagcaac tgtttatcaa aaacacagct ctctgctaaa tcgtaagatg atgtataggg
     4621 ggtgacgcct gcccggtgct ggaaggttaa gaggagtgct tagcgtaagc gaaggtatga
     4681 attgaagccc cagtaaacgg cggccgtaac tataacggtc ctaaggtagc gaaattcctt
     4741 gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt gggcactgtc tcaacgagag
     4801 actcggtgaa attttagtac ctgtgaagat gcaggttacc cgcgacagga cggaaagacc
     4861 ccatggagct ttactgcagt ttgatattga gtgtctgtac cacatgtaca ggataggtag
     4921 gagtctaaga gatcgggacg ccagtttcga aggagacgct gttgggatac tacccttgtg
     4981 ttatggccac tctaacccag ataggtgatc cctatcggag acagtgtctg acgggcagtt
     5041 tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc ctcagaatgg
     5101 ttggaaatca ttcgcagagt gtaaaggtat aagggagctt gactgcgaga gctacaactc
     5161 gagcagggac gaaagtcggg cttagtgatc cggtggttcc gtatggaagg gccatcgctc
     5221 aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtt cacatcgacg
     5281 gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc ggtcccaagg
     5341 gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc gtgagacagt
     5401 tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga tctgctccta gtacgagagg
     5461 accagagtgg acttaccgct ggtgtaccag ttgtcttgcc aaaggcatcg ctgggtagct
     5521 atgtagggaa gggataaacg ctgaaagcat ctaagtgtga aacccacctc aagatgagat
     5581 ttcccatgat tatatatcag taagagccct gagagatgat caggtagata ggttagaagt
     5641 ggaagtgtgg cgacacatgt agcggactaa tactaatagc tcgaggactt atccaaagta
     5701 actgagaata tgaaagcgaa cggttttctt gaattgaata gatattcaat tttgagtagg
     5761 tattactcag agttaagtga cgatagccta ggagatacac ctgtacccat gccgaacaca
     5821 gaagttaagc cctagaacgc cggaagtagt tgggggttgc cccctgtgag a
//
LOCUS       DAVLTT010000088         5802 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLTT010000088 DAVLTT010000000
VERSION     DAVLTT010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5802
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.088"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(204..932)
                     /locus_tag="VYN15_001959"
                     /pseudo
     CDS             complement(204..932)
                     /locus_tag="VYN15_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(1192..1503)
                     /locus_tag="VYN15_001960"
     CDS             complement(1192..1503)
                     /locus_tag="VYN15_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453221.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(1518..2804)
                     /locus_tag="VYN15_001961"
     CDS             complement(1518..2804)
                     /locus_tag="VYN15_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1453222.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            3428..3610
                     /locus_tag="VYN15_001962"
     CDS             3428..3610
                     /locus_tag="VYN15_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1453223.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLCFNEKFGTENT"
     gene            3620..3985
                     /locus_tag="VYN15_001963"
     CDS             3620..3985
                     /locus_tag="VYN15_001963"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1453224.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            3982..5172
                     /locus_tag="VYN15_001964"
     CDS             3982..5172
                     /locus_tag="VYN15_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV1453225.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     DLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
BASE COUNT         2023 a         1027 c          957 g         1795 t
ORIGIN      
        1 gcttattaat ttttttcaaa atatctaaga catcgcttct ttgtttaatt tgataggctt
       61 tgatacctaa gctccgactt tatcacttaa aaaataaaaa agacagctaa tctcttgcgc
      121 atcaggggat ttcgccattc tttaatctcg tttaagtgtt gtatatggag ctttgcataa
      181 ttttttaaaa ctaaacaact acattaagca cgaactgtga cgctggttcc atcttcctta
      241 taaagattga taagcccctc tttaagagct cgaaccatgt ctccagcttg aacaggttgt
      301 gggactttaa tagtcaatag ttccattgga tttggagcgc ggtcgatttt attgccttta
      361 gcatcatgca aatcttcaat ataggtttca aaatgacgga aacctggacc ataaaactca
      421 acttggtccc cttcgttaat gacgttccgt tgacgaatgg ttgctgtttg tgccgcatca
      481 tcataagaaa ccacttcagc gacaaacttg tactcaggga ttttacgacg agcaccaaac
      541 aactgctcat tttcagatgg tataccgtag tagaaacctg ttgccaattc acgttgggca
      601 accttccaca tctcgtccac caagtcttgt ttgatagctt caaacttttc aggactttca
      661 agataggcat ccacagccgc cttgtagcag ttggttactg ttgatacata gtgaatagac
      721 tccatacgtc cttcgatttt tagactgtcc acaccatttt caatcatatc tgagatatgg
      781 tcaatcatag acatatcaac ggctgacatt gaaaattctt ctggaatctc accctgcaaa
      841 ctcttacgtt ctttcccaaa tggcatatcg taaaggtcgt acttccaacg gcatgactga
      901 gaacatccac cacggttggc atcacgcata ctctagacgg attgttttga caattctaac
      961 cttttagact ttgcataata actgttaaac agtcgaaaat taccccagtt ttaacaagta
     1021 gtcaaaatac cagataaagt aaaaaggggc taggaaaaaa gtctttaaaa tcttaaaaac
     1081 gcatagtatc aggtattgaa caatcttgat attatgcgtt ttattgtggg aagatttact
     1141 tcattttctc ttggaattga gttttctcct acttcaaaac tagatgattt gctatttaaa
     1201 atagcgttcc ttatgatttt ggcaacctgg attaaagcga gaaaaacaaa agaggcaact
     1261 taagctttct ttatattgct tatatgttaa tagttttaga caaacaccac ataaaatagg
     1321 cttatcctgt atcaaagata agggataagg ctcaaaaggg tgattttcta atgaatcatg
     1381 acaccgataa caagcataat actttttaca atcatagcat tgtaaagcaa taatatccaa
     1441 cttgctatgg taatgaatgc atcttgtttg cttatccact aagaaaccct gtgcctctat
     1501 catttccttt tcctttctta agctcgaact gtgacgctgg ttccatcttc cttataaaga
     1561 ttgatgagtc cttcttttaa tgcacgaacc atgtctcctg attgaacggg ttgtgggact
     1621 ttaatagtca atagttccat tggatttgga gcgcggtcga ttttattgcc tttggcatca
     1681 tgcaaatctt caatataggt ttcaaaatga cggaaacctg gaccataaaa ctcaacttgg
     1741 tccccttcgt taatgacgtt tcgttgacga atggttgctg tttgtaccgc atcatcataa
     1801 gaaaccactt cagcgacaaa cttgtactca ggaattttac ggcgagcacc aaacaactgc
     1861 tcattttcag atggtatacc gtagtagaaa cctgttgcca attcacgttg ggcaaccttc
     1921 cacatctcgt ccaccaagtc ttgtttgata gcttcaaact tttcaggact ttcaagatag
     1981 gcatccacag ccgccttgta gcagttggtt actgttgata cgtagtgaat agacttcata
     2041 cgtccttcga tttttagact gtccacacca ttttcaatca tatctggaat atggtcaatc
     2101 atagacatgt caacggctga cattgaaaat tcttctggaa tctcaccctg caaactctta
     2161 cgttctttcc caaatggcat atcgtaaagg tcgtatttcc aacggcatga ctgagaacat
     2221 ccaccacggt tggcatcacg catactcatg tggtttgaaa gagtacaacg tccagagtat
     2281 gaaatacaca tagctccatg gacaaaggct tcaatttcaa catctgtacg tttgcggatc
     2341 tcagctaatt cttccattga aacctcacgc gctaaaacga cacgagtcaa gcctagctct
     2401 ttccagaact caagggtttc atagttagtg gcactggctt gggtagaaag gtggatttca
     2461 aggcctggtg cttcagtcgc tgcaatcata atcaaggctg ggtcagatac gataactgct
     2521 gcaatcccaa tatcacgcag tttacggaac cactcaccag caccagcttc atttccttcg
     2581 tgcataacca tattagccgc tacatagacc ttggcaccat acttggccgc aaactgcacg
     2641 ccttcttcca tctgttcgaa agtaaagttt cccgcacggc tacgaagacc ataggcctga
     2701 ccaccgataa agacagcatc tgctccatac tgaacagcta cctttagctt ctctaaagtc
     2761 cctgcaggtg ataaaacctc aggacgtttt aatgtttttg tcatgatttc tcctatttgc
     2821 aatataaaag tttgacattt ttccttctca ttttatagta aataaaggat aaaatcaagc
     2881 ctagacggat tgttttgaca attctaatct tttagacttt gcataataac tgttaaacag
     2941 tcgaaaatta tcccagtttt aacaagtagt caaaaagtct agaaaagtaa aaaccagtat
     3001 ccaaagatac tgactcgtaa aaatacataa attagtcctt agatgactac tcccactctg
     3061 ttgctcctat aatggaaaag gattgataca gtctagaata tcgctttttt atttattatt
     3121 ctgatataaa actgttagaa ttgatttttt gttttatacc caaatatgaa tagagacgta
     3181 gctaataagt tgaataacat atttggaaaa atgagaaata gcaatattac tagaactttt
     3241 agaaacaatc aatatttaaa aagaaaaaag ctcaaagaat ttattaaacc atgttataat
     3301 agatatagct ataattttat ttataacaag aggatagaaa tgaccgaatt agaaagaaaa
     3361 aatcgaaaaa ttagctaaga aatattctga taacttaaac atcaaagttc aagagagagt
     3421 tcgtgaaatg gcaaatgata ataagagcca ttatttgata tacagagttt taggtatttc
     3481 atttgaagaa ggagaaaata tcgatttgta tcaaaataaa ggtcgttttt tatacaaata
     3541 tgctggttca tttttagaag aagctgcagt actatgcttt aacgaaaaat ttggtacaga
     3601 aaatacttaa aaagttaaca ttcctaattc tgaaagtaca aaacctaaga cttttgaaat
     3661 tgattgttta gtcggagaaa aacacgcata cgaaataaaa tggtgggatg caactacaga
     3721 tggagaccat ataactaaag aacacactag aataaaagtt attcataaca aaggatatat
     3781 accaattcgg ttaatgttct actatccaaa tagaactcaa gctataaaaa ttcagcaaac
     3841 tttagaaaca ttgtataacg gtattggagg gaaatattat tatggagatt ctgcctggga
     3901 acatttaaga gcagtgaccg gtattgattt acttagtatt ctaacagata ttgcaaataa
     3961 aaaaacaggg gtaaaatcaa aatgacagta ttaaaaggag ataacttaga aatattaaaa
     4021 actattgaat cctcaagtat tgatttaatc tatatggacc ctcctttctt tacacagaaa
     4081 acccaaaaat tatctaataa caaaaatatt atgtattcat tcgaagatac gtggacttcg
     4141 attgaggatt acaaagaatt tttgtctgta agattagaag aatgcaaaag agtgctaaaa
     4201 aatagtggca gtattttcgt tcattgtgat aaaattgcaa atcatcatat tagattaatt
     4261 ttagataata tctttggagc agatatgttt caaagcgaaa ttatatggaa ctataaacgg
     4321 tggtctaatt caaaaaaggg attattgaac aatcatcaaa acatttactt ttattcaaag
     4381 tcaaaagatt ttaaatttaa tacaattttt acagagtatt cttctactac aaatatcgac
     4441 caaatactag tggaacgaaa acgagatgga aactctaaaa ctatatataa agttgataat
     4501 aatggtaact atattctagc aaaagagaaa aatggagttc ccctttcaga tgtttggaat
     4561 ataccatttc ttaatccaaa agctaaagaa agagtaggtt atcctacaca aaaacctatt
     4621 ctgttattag aacaaattat aaagattgct actgataaaa atgatatagt tttagacccg
     4681 ttctgtggaa gtggaactac tttagtagcc tccaagattt tgaatagaaa ttatatgggg
     4741 attgatttat ctgaggaagc tatcaatata actcagcaac gtctggaaaa tgttataaaa
     4801 acaagttcag atttattgaa taaaggaatc gaagcatata gaaccaaaac tgaggaagag
     4861 gaaaacattc ttaaattatt acaggcaaaa attgttcaaa gaaataaagg aattgatggt
     4921 tttttaccta aacattttca aaaaaaaccg atacctataa aaattcaaaa aaataatgaa
     4981 tgtctgaatg agagtatctc tttattacag aatgctataa actccaaaaa acttgatttt
     5041 ggagtagtta taaaaactca ttcagataat ttattatttg attttgatac gattcctgaa
     5101 aatataatag tagttgacca ttttgaactt acaatcgaaa aatggttaag taaaagtcaa
     5161 cagttactat agtttgcaaa ttatttacag aaagaacaaa aatgctctga aacactgatt
     5221 tcaaagcatt ttttgttagt ttaaaattac tcccattctt cttttccaaa cgtacaatat
     5281 atccaaaacc attcaaaata ctagattcta ttttttataa tatcactaaa tccacctaat
     5341 tataggacgt tttcagattt ttagtcccgt cccagtccca gtaccggaga aatattgttt
     5401 taatataata tctctttttg tcttctaagc tcttaaaagc aaaagaacaa gtaaagagtc
     5461 aagacaagga taaaaagtcc atattagggc aaataaaaag ctttaagaca gatgacaaat
     5521 ctaagtcaaa taagaaagac catagcaaag gtgcagagag ataaatattg gcggtcttcg
     5581 gactgccttt atttttttac ttaatttaat gcagtaaatc atacgattga aaggaatctg
     5641 cgttatatgc tataattagg tagttaatct atacatttag aaaggtaaaa tatagaattg
     5701 gagaatgata tgggattttc atataataaa ttgtaaccgc ccaataacga agtctattga
     5761 aaaatctcca gattagtgaa ctcacggata gttcctaatc tg
//
LOCUS       DAVLTT010000089         5796 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLTT010000089 DAVLTT010000000
VERSION     DAVLTT010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5796
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.089"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            1..945
                     /locus_tag="VYN15_001965"
                     /pseudo
     CDS             1..945
                     /locus_tag="VYN15_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1061..1864)
                     /locus_tag="VYN15_001966"
     CDS             complement(1061..1864)
                     /locus_tag="VYN15_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV1453226.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(2139..2894)
                     /locus_tag="VYN15_001967"
     CDS             complement(2139..2894)
                     /locus_tag="VYN15_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV1453227.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2964..5615)
                     /locus_tag="VYN15_001968"
     CDS             complement(2964..5615)
                     /locus_tag="VYN15_001968"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV1453228.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGSEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(5627..>5796)
                     /locus_tag="VYN15_001969"
     CDS             complement(5627..>5796)
                     /locus_tag="VYN15_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV1453229.1"
                     /translation="KLKHSRYYISKISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSK
                     IGLVKIVNKSN"
BASE COUNT         1756 a         1210 c         1113 g         1717 t
ORIGIN      
        1 ataaagtctg acatgaaggc tggactaaag atagagtttc tcttgaatac tgcctcccaa
       61 gtcgtacgat acttcttaac tggctagcac aatacaggaa aaacgggtat actattgttg
      121 agaaaacaag agagagagta cctgagagcg gagaaggcca tcctaaaaaa gttaagagaa
      181 ctccgattga aggaggaaaa agagaaagaa gaaagacaga aattgttcaa gaattaatga
      241 ctgagttttc gttagatctt cttctaaaat ccattaaact agctcgttgg acctactact
      301 atcacttgaa acagctagat aaaccagata aggaccaaga gcttaaagct gaaattcaat
      361 ccatttttat ctaacacaag ggaaattata cttatcgtcg ggttcattta gaactaagaa
      421 atcgtggtta tctggtaaat cataaaagag ttcaaggctt gatgaaagta ctcaatttac
      481 aagctaaaat gcgacagaaa cgaaaatatt cttctcataa aggagacgtt ggtaagaaag
      541 cagagaatct cattcaaggc caatttgaag gctctaaaac aatggaaaag tgctacacag
      601 atgtgacaga atttgccatt ccagtaagta ctcaaaagct ttacttatca ccagttttag
      661 atggctttaa cagcgaaatt attgctttta atctttcaac ttcacccaac ttagaacaag
      721 tacaaacaat gttggaacag gcattcaaag agaagcacta tggtggaatc cttctttggg
      781 attctgaaat cggaaatgtt ttacggttat gagaagtcgt ttcagtcgct taagcaattg
      841 gaacaagcta ttgtagacta tattgattac tacaacaata aacgaattaa ggtaaaacta
      901 aaaggactta gccttgtgca atacagaact aaatccttcg gataaattat ttgtctaact
      961 ttttggggtc agtacaccta aaactttgat gatatacgtt ttcttgtgag aatatttact
     1021 tcatttttgc ctaaaattca atgtttactc agtatttgga ttatgaaaaa tcgaggtcta
     1081 aatctagata cattttttct gaagacaaat cattttgacc accgagcaag agattttcaa
     1141 aaaaagctgt taaaaactca gaacgtcgct gtaaaatctt tgcattatct aataccaagg
     1201 catcacgaaa atatttggaa tgttgctgaa atggtgtatt atcaatatca aaaccaaact
     1261 cacgaagata ctgaatcaaa aagaccgtta ctgtccgagt gtttccttcg cgaaatggat
     1321 gaatctgcca gattcctgaa ataaaatgct ggatttgttt aaccacatcc gcctgagtta
     1381 gtgtcgcata tgcaacttgt ttttcctgat taaaatcata atctaaggtc atttgaatca
     1441 tggagtaatc agagtacaca acactttcac cattcaaaac aggttcattc tttgtgatat
     1501 tggtctgacg aaattgcccc accggaatag agggttcaaa tatatcttga aacaactcct
     1561 tatgaatagc aagtaaggtc gcaggactaa agctaaagcc tcttcgagac aatagttcta
     1621 caatacgtag agaaaccaag tctgcctctt ccgtacttgc atcaatagta tggtgataag
     1681 ccgttgcatc ctcataaacc tgctcataag tcagttctcc ccgggactgt ttctcagcca
     1741 aagattccat atacgctgat ggcactagat tgtcaacttt ctgcagacca aaacctatcc
     1801 gccataaatc acgcttcgct tcataagaca agtttggatt gtcaatgttg taagttggtt
     1861 gcatagaaat atcctttcaa ttgtttttct tcattaccag taaatcacga aattggttgg
     1921 aaactggctt aaactataaa aagtcctcac aataggttct atgatatata tatacttcat
     1981 gtaaataata aaagagttat aatcagcact actgataaat tcaataccga tttcgccatc
     2041 ttaaaactta gtcaaacgaa taccgttgat ttccagttca ttaagtcgtt gacctgtcaa
     2101 gacttctcgt tccttcaact ggaaaagtta agggggaact aatacaaatc ctctacgctt
     2161 ctatattcaa tgatttcatt tttgataata ttctttttaa actcaaaatg ttttaaagga
     2221 ttatcgatta acactaactt tggaatatca tctagatttg tgaccaagga taaaataaaa
     2281 tccgattgaa actccttgac tttttcaaat tcttttgcag ttaaacgcac acgcccctta
     2341 gattttcgga taccttttac ttcggcaagg taagaatact cttggacatc tacctgaaag
     2401 tcatatccat caccataaag acgggcatcg gttaactgtc caccttggaa tttttcttct
     2461 ttatcaaaat gaaggataaa ataattctca gcctccattc ccgtttcctg tagacgtttg
     2521 aatttagttc gaactattgg tttttcaacg atggttatgc ctgttttctt cccttcactg
     2581 gcaagtaaca ttttaactat ttcagcataa ctatgaacat cttcatttcc aaacatcata
     2641 tcaattaaat ctttacgaaa acgataaact tcagctttct gccaccaacc ttttcgatta
     2701 ttgtcaaaat aaggatcaaa taaatccatt ctatttttta caactccagt tgtttcagca
     2761 attcccagag aaaccacata gcgataaaac tccgacttgc tagagcattg aaattctttt
     2821 ataaaaagct tgtcaaactt ggcaagaccg tagccaatta aatttaacaa ttcataatga
     2881 gggtgtttgg acatcacttt ctccatcaat agatattgat ttcattatac caaaaaacac
     2941 ggctcatcac cgtgtttctg tgtttatttc accaacttct tcatctcatc aatacgtgct
     3001 acggtcacat catacttggc ttggtagtcg gcttgtttgt ctttttcttt ttggacaact
     3061 tctggtttag cgttggcgac gaagcgttcg ttagagagtt tcttaccaac catgtccagt
     3121 tctttttgcc atttagcgag ttctttgtcg agacgagcta gttcttcttc aacattgagg
     3181 agatcggcca gtggcaagaa gatttcggat cctgtaataa cgcttgacat agccagttca
     3241 ggtgcaggga tggttgatgc gatttccaag tgttctggat ttgtaaagcg tttgatatag
     3301 ttgacattgc tgttaaagaa ggcttccaag tcactatcgc ttgtcttaac aaggatggtg
     3361 ataggcttgc ttggtgctac atttacttcc gcacgcgcat tccgaacagc acgaattaag
     3421 tctttgagac tttccacacc agtgtgagcc gcaaggtctt caaaggctag attaacagtt
     3481 gggtatgcag ctgtcacgat agaaccttct gagatttgtc caaagatttc ctctgtcacg
     3541 aatggcatga ttgggtgaag gagacgaagg atcttgtcca aagtgtatag tagaacagaa
     3601 cgtgtgatga ctttctcttc ttcgttatcg ctataaagga cttccttggt caactcaaca
     3661 taccagttgg caaattcttc ccaaatgaag ttgtaaagga tatgaccagc cacaccaaac
     3721 tcgaacttat caaagttttc agtaactttt gcaatggttt cgttgagatt gtggagaatc
     3781 cagcggtccg tcacattacc agcctcacct gttgcaactt ttgtgacatt gtcatgcgcc
     3841 acatccagcg tcaaacctcc attgttcatg aggatatagc gagaaatgtt ccaaatcttg
     3901 ttaataaagt tccatgaagc atccattttc tcataagaga aacgcacgtc ttgtcctggc
     3961 gcagaaccgt ttgaaaggaa ccatcgaagg gcatcggcac cgtatttctc gataacatcc
     4021 attgggtcaa tcccgttacc gagagactta gacatcttgc gtccttgctc gtcacgaatg
     4081 agaccgtgga taaggacgtt ttggaatggt tgacggcctg tgaattccaa tgactggaag
     4141 atcatacgag acacccagaa gaagatgatg tcgtaacctg ttaccaaggt tgaagttggg
     4201 aaataacgtt taaagtcttc tgagtcgact tcaggccagc ccatggttga aaatggccag
     4261 agggcagaac tgaaccaagt atccaagacg tcttcgtcct gagtccatcc gtcaccttct
     4321 ggagcttctt cgccgacata catttcacca tcagcattgt accaggcagg gatttggtga
     4381 ccccaccaaa gctgacgaga gataacccag tcgtggacat tttccatcca ttgaaggaag
     4441 gtatcgttga aacgaggtgg gtagaattcg accttgtcct ctgtgtcttg gttggcaatg
     4501 gcgttcttag ccaattggtc catcttgacg aaccattgag tagacaagcg tggctcaact
     4561 acgacacctg tccgttctga gtgaccgact gaatggacac gtttttcgat tttgacaagg
     4621 gcaccgattt cttccaactt agcaacgact gccttacgag cttcaaaacg atccatgcct
     4681 gaaaattcaa aggcaagctc attcatagtt ccgtcgtcgt tcatgacgtt gacttgtggc
     4741 aagttatgac gttggccaac caagaagtca tttggatcgt gggcaggtgt gattttcacg
     4801 acaccagtac caaactcagg atctgcgtgc tcatctccaa cgattgggat gagtttatta
     4861 gcgattggaa ggatgacgtt tttaccaatc aagtccttgt agcgcgggtc ttctggatta
     4921 accgcaaccg caacgtcccc aaacatagtc tcaggacgag ttgtagcaac ttcaagggcg
     4981 cgtgaaccat cttccagcat gtaattcatg tggtagaagg caccttctac atccttgtga
     5041 atcacctcaa tatcagaaag ggctgtgcga gctgctgggt cccagttgat gataaactca
     5101 ccacgataga tccagccttt cttgtaaagg tccacaaaga ccttacgaac agcttttgac
     5161 aaaccttcgt caagagtgaa acgctcacga gaatagtcta cagaaagccc catcttgccc
     5221 cattgttcct tgatggtagt ggcatattcg tctttccatt cccagacctt cgtcaagaaa
     5281 gactcacgac ctaggtcata acgcgtaata ccctcaccac gtaagcgctc ctcaacctta
     5341 gcctgagtcg caataccagc gtggtccata cctggaagcc aaagggtatc aaagccctgc
     5401 atgcgttttt gacggatgat gatatcctgc aaagtcgtat cccaagcgtg accaaggtga
     5461 agtttcccag ttacgtttgg tggtggaatc acgattgaat aaggcttagc cttttgatcg
     5521 cctgaaggct tgaaaacatc cgcatcaagc catttttggt aacgaccagc ctcaacctcg
     5581 gctggattgt atttagatga aagttcttta gacatgtgtg ttctccttaa ttacttttat
     5641 tgacaatttt aaccaaacca atttttgaaa gttcaatata aatctcttca atttcagcaa
     5701 atgctgcaag tggtgacata gtataatttc caggattata tttaagatca tacttgctta
     5761 tctttgaaat ataataccta gagtgtttca atttta
//
LOCUS       DAVLTT010000090         5583 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLTT010000090 DAVLTT010000000
VERSION     DAVLTT010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5583
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.090"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            121..285
                     /locus_tag="VYN15_001970"
     CDS             121..285
                     /locus_tag="VYN15_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1453230.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            369..935
                     /gene="amaP"
                     /locus_tag="VYN15_001971"
     CDS             369..935
                     /gene="amaP"
                     /locus_tag="VYN15_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV1453231.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            947..1117
                     /locus_tag="VYN15_001972"
     CDS             947..1117
                     /locus_tag="VYN15_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV1453232.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1156..1764
                     /locus_tag="VYN15_001973"
     CDS             1156..1764
                     /locus_tag="VYN15_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1453233.1"
                     /translation="MSNEKNINTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1795..1998
                     /locus_tag="VYN15_001974"
     CDS             1795..1998
                     /locus_tag="VYN15_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1453234.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2108..2380)
                     /locus_tag="VYN15_001975"
                     /pseudo
     CDS             complement(2108..2380)
                     /locus_tag="VYN15_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2420..2866)
                     /locus_tag="VYN15_001976"
     CDS             complement(2420..2866)
                     /locus_tag="VYN15_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1453235.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYIMKKGR"
     gene            2936..3595
                     /locus_tag="VYN15_001977"
     CDS             2936..3595
                     /locus_tag="VYN15_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV1453236.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLSQVILITAG
                     LTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLL
                     V"
     gene            complement(3647..4798)
                     /locus_tag="VYN15_001978"
     CDS             complement(3647..4798)
                     /locus_tag="VYN15_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV1453237.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGNRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(4813..5544)
                     /locus_tag="VYN15_001979"
     CDS             complement(4813..5544)
                     /locus_tag="VYN15_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453238.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQIWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTFYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
BASE COUNT         1720 a         1020 c          939 g         1904 t
ORIGIN      
        1 atcaaagaaa ttgatttttt gatattaaaa taaaaaagga gggtaggcag tgttgtgatc
       61 aattattgct ggaggtctta ttggtctctt ggcaggtaaa atcactaaaa aagtagttct
      121 atgggaatca tcgcaaatgt attcgctggt ttagtcgggg catatgcagg acaatctctt
      181 ttaggtagtt ggggtccatc aatcgctgga atggctttgc tcccatctat tgtaggtgca
      241 gcgattgtga ttactgtagt gtcattcttt acaggtagaa agtaaacttt tcgccagtaa
      301 agttagcaaa ctatttttaa atcaatgacg ggaaaaatag tttaaatgtt aaatcgaaag
      361 gattgtatat gtcaaaagca aagaaaatat gtttcattat tttctgtatt ttaatcttga
      421 caattttcct tcctgttttg atagattatc atcaagttag tgatctaggt attcatctac
      481 ttagctggag acagaactcc gtagttgaat tctatcttgc tagatatgtc ttttggggga
      541 cagtggttct atcaacttta gttttattat ccattttagt tgtgatgttt tatcctaagc
      601 gttacttgga aatccaactt gaaactaaaa acgatacatt aaaattaaag aattcggcaa
      661 tcgaaggttt tgttagaagt ttggtgagtg atcatagatt gatcaagaac ccaactgttc
      721 atgtaaattt acgaaaaaat aaatgtttcg ttcatgtaga aggtaaaatt cttccttcag
      781 acaacatcgc tgacagatgc caaataattc aaaatgaaat aactaatgga ttgaagcagt
      841 tttttggtat tgagcgtcaa gtaaaacttg aagttgcagt aaaaaattac caaccaaaac
      901 ctcaaaacaa aaagactgtt agtcgtgtga agtaaggaag taaaaaatgg aatggcttaa
      961 acaatatcga tatccaatta tcgctggtct cataggcgta tttctggctt gtttgattgt
     1021 ctcctttggc ttcttcaaaa caatatttgt attgatttta ggagcactgg gagttgcagc
     1081 tggattatat atcgaaaaaa actatataga taaataaaaa aataaaaatt actaatttaa
     1141 ttaaaggagt ttcatatgtc aaacgaaaaa aacataaaca ctaacgtaga aaagaaagat
     1201 gctactgttg tagctcacga aatcaaaggg gagcttactt acgaagataa agttatccaa
     1261 aaaatcattg gtctttcact agaaaacgtt tcaggtcttt tgggaatcga tggtggtttc
     1321 ttctcaaatc ttaaagaaaa aatcgttaac agcgatgacg taacaagtgg tgttaacgta
     1381 gaagttggta aaacacaagt tgcagttgac ttaaacgtta ttgttgagta ccaaaaaaat
     1441 gttccagctt tatattcaga aatcagagaa atcgtatctt cagaagttgc taaaatgact
     1501 gacttggaaa ttgttgaaat caacgtaaac gttgtcgaca tcaaaactaa agaacagcat
     1561 gaagcagact cagtaagcct tcaagatcgc gtatctgacg ttgctgaatc aacaggagaa
     1621 ttcacttcag aacaattcga aaaagctaaa tctggtcttg gatctggttt ctcaactgtt
     1681 caagaaaaag ttagcgaagg tgtagaagct gttaaaggtg cagcaaatgg tgtagtatct
     1741 cacgaaaaca ctcgtgtaaa ctaagataaa ataaatataa caggagaaat tatcatgtca
     1801 gtagaagaaa aattaaatca agctaaaggt tctattaaag aaggtgttgg gaaagccatc
     1861 ggtgatgaaa aaatggaaaa agaaggagca gctgaaaaag ttgtttctaa agtaaaagaa
     1921 gttgccgaag acgctaaaga cgctgtagaa ggtgctgtag aaggtgttaa aaacatgttg
     1981 agtggcgacg ataaataagg ttaaaagtta ctttatcttt ttggtaacat tagtcaaaag
     2041 agtctgagtc aagatgattc tcagaaaaca aaaagctaga gattcccaat tgcggaactc
     2101 tagcttttta attttgcctc tttctcttat tatatttcag caggttgttg gccatgagta
     2161 tgaatcccat gtcaattctc acttgacgct tacctctcag atgacatctc ttataaccca
     2221 aacaaacctt tatctgccca aagacagatt tcatatcaat cttacgttta gcgaaaattt
     2281 gtctaccctt ggaagataaa agtgcctgat attctttagt ttttaaacac tggtaacgtt
     2341 cattcatata cagtctcttt tgaggggctg attcaggttc ataatcgcag ttaacattga
     2401 tttcaaggct gtttgctttc tatctcccct ttttcatgat atattttcgt acaggtgctt
     2461 caaccatttg aacgatttca aatccttctt tttggtaaag attctgagct ctttgatttg
     2521 cctcgaagac atttagagaa atactatcta tatcttcatt ttcaaaggcc aaactaacaa
     2581 atttccttaa agcctggcta cctaagcctt gctcctgttt ctgggggttg ataaaaaatc
     2641 tcccgatatg aagattgctg tcttctagcc tgattttctg gataaatccc acaaactctt
     2701 gttcatcaaa gattgaaaag actccttcca aggcttgaag ggtcagtaga aaaggaatcc
     2761 ttggtcccat ccattgttct tgaaaggatt tgcctaggga gttggaccac tggcatacaa
     2821 attgagcgtt ttctgtgctc accttttctt caaaacgaat tgtcatcttt tcctcaccac
     2881 cttatctatg tttctccatt atactatttc tcccattttt tacgaataga taagtatgat
     2941 tgatttttat ttttttctcg tcgggagcat tctcgcttcc tttcttggtt tggtcattga
     3001 ccgttttcca gagcaatcca ttatcagttc agccagtcac tgcgattcct gtcagactcg
     3061 cttgcgtccc ttagatttga ttccgattct ctcacaggtc ttcaatcgct tttgctgtcg
     3121 ctactgcaag gtccgctatc ctgtctggta tgccctcttt gaactaggct taggactcct
     3181 ctttctgctt tactcttggg aattactttc cttgagtcaa gtcatcctaa tcactgctgg
     3241 tttgaccttg ggcatctacg actttcgcca tcaggaatat cccttactgg tctggatgac
     3301 tttccaccta atcctaatag cttcctctgg ctggaatctg gtcatggtct ccttcctcat
     3361 acttggaatt ttggctcatt ttatcgatat ccgcatgggt gcaggggatt tccttttttt
     3421 agcttcttgc gctctcgtct ttagcgtaac ggagttactg atcttgattc agttcgcttc
     3481 tgcgacgggt atcctggcct ttctcctgca aaagaaaaag gaaagacttc ctttcgtgcc
     3541 tttcctctta cttgctgctt gtgtgattat ttttggtaag ctactgcttg tctgataaaa
     3601 tccaatttct gccatatgtc cttcatgaaa ttatttcaca gttaaattat aaattatttc
     3661 ttttgtacaa agggatgatg ttatcaaatc gatctgttct tctatcttct tgatactgat
     3721 caaaaaattt catttcgact gaaaatattt cgcttataaa ctgtaaacga atactttgtt
     3781 tagacattat agtcgctaga ctgactagat gattactcaa aacgacgtcc agaatactct
     3841 ttactttgct tggtttttta acaaaaattt gatcatccaa aggttcaatc attttgtaac
     3901 ctttttgcgc aatttgacga taaaagtaag aatgttgctt tggagtcaat aatcctaact
     3961 taaaagctcg atactctaaa gcctgtatcg aaacattcaa atccgacttc aataaaatat
     4021 aactatcagg attgctgaca cgcttgccaa ccctctcttc aaatttgact aaaaactctt
     4081 cttttggcaa taaaaaacat gatgcaaaat aatttgcttc ttgctccaaa cgattgccat
     4141 cttcattcat atctttatat ttgtgtaaaa gaatatgtcc tagctcatga gctaagtcaa
     4201 aatttcgacg tacagatgat ttattcgttc ccaacacaat ataaggtctt cccaattttg
     4261 accatgcgct ataagcatca gcttggccat taattaatcg ttccacgata tagatgcctg
     4321 aacgttctaa tttataaagc aaatcatgat tatcttttga aatacctaat ttttccctgg
     4381 cataaagagc caattcctca atggattctc ccttatgata agattcactc actacattac
     4441 ttaggtcatg aattgtaata ttaggtataa ttacaaaact ttcaaaataa tcaatcaaac
     4501 tatctacctt atgtaaatac atagtttgaa tatctattgt tttccgtgtt gctaggtctg
     4561 catttctaaa ggcaattaca gaagaatcaa atcgaatgct ctcttcttcc tgttcaaaat
     4621 aagttaaatc aacatgaaat tggttggcca aatgcatttt ggttgataat ttaggtttcg
     4681 tttcgttgga ctcaaactgc caaatggctt gttccgttaa attaattctc tgagctaatt
     4741 ctgctctact taaaccattt aacagccgta attctttcaa tacccgacca ttaaacattt
     4801 acatactcct tactactttt gaccttcttg tttttctatt cttggaataa tttcaaaatc
     4861 ttctgtttcc gataattctg aaaaattagg aatatcttga tatttagctt cttcgaaatg
     4921 gtacgaactt gattgaatat actcagacaa atcttgaatc aagtgtaact gaccagttcg
     4981 tgcatcaggc ataacaacat ctacagatat aatattgttt tctgagtccg cctcataagt
     5041 taaaatcata aatttttcga tattcgaatt tttagtagct tgttcaattt cttgaatcat
     5101 ttcatcagaa actaactcca tctgaattgg aaaggaatga ctatcttcat catttttgta
     5161 ggaagaatgt tgattaagat aaaatgtatt catctgagca tattcaaata agtagccact
     5221 cttatttttt tgtaccaaag gaaattggtt cgtaagtcgc ttcttaccct ttataattaa
     5281 caatactttc ccatattttt ctgtatttgt ttcaaattct aaatatcccc aaatctgtcc
     5341 tgctaattgt aatttatact caaacaaatc tgctgatgca aatgcagtat caatatgatt
     5401 aggtcgcgtc catgcataac cattcgacac tatcattgtc tctctttttt ctagacgttc
     5461 atctacataa tctttttgcc ctttcatcaa agtatctaca attttttgtg cctcaagcga
     5521 atcaaagaga tcctgattca acataattct tcctcctcca aatacttttt aatgaattat
     5581 atc
//
LOCUS       DAVLTT010000091         5372 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLTT010000091 DAVLTT010000000
VERSION     DAVLTT010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5372
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.091"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            38..1792
                     /locus_tag="VYN15_001980"
     CDS             38..1792
                     /locus_tag="VYN15_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1453239.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNINNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            1776..3497
                     /locus_tag="VYN15_001981"
     CDS             1776..3497
                     /locus_tag="VYN15_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1453240.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            3508..4092
                     /locus_tag="VYN15_001982"
     CDS             3508..4092
                     /locus_tag="VYN15_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1453241.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     YMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            4092..4787
                     /locus_tag="VYN15_001983"
     CDS             4092..4787
                     /locus_tag="VYN15_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1453242.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKIAMRVRGINF
                     KKPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            4775..>5372
                     /locus_tag="VYN15_001984"
     CDS             4775..>5372
                     /locus_tag="VYN15_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1453243.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRI"
BASE COUNT         1923 a          708 c         1008 g         1733 t
ORIGIN      
        1 atatctaaaa gggatattaa agaaaggaga tatgcttatg aagatttaca aaaaactatt
       61 tgcttatgtc caagataaga aatatcttgg ggttttggcc ataatttttt ctgctatatc
      121 tgctctactt acagtatatg gatattattt aatctacaaa tttctagata agttaataat
      181 taattcaaat ttatccggtg cagagagcat agcattaaaa tctgttatta cactaacaag
      241 tggagcgata ttttattttg tctcaggaat gttttcacat atcttgggat tcaggcttga
      301 aacaaattta agaaaaaggg gaatcgatgg tctggaaaaa gcaagtttta ggttctttga
      361 cttaaatcca tctggtcaaa taagaaagat tatagatgac aatgctgcac aaactcatca
      421 ggtggtagca cacatgattc ccgatagttc tcaggcaata atcacacccg tacttgtact
      481 tgcacttggc tttatagtaa gtataagagt tggcataatt ttgcttgctc ttactataat
      541 tggtggctta attttagggg caatgatggg cgagcaagaa tttatgaaga tataccaaga
      601 atccctatct aaactaagtg ctgaaactgt tgagtacgtg agaggaatgc aagttgtaaa
      661 aatatttaaa gcaaatgtag agtcttttaa aagcttttat aaggcgataa aagattactc
      721 aaagtatgct tatgattatt ccctatcttg taaaaggcct tatgttttgt atcaatggtt
      781 attttttgga ctgattgcaa ttttaattat tcctatagtt tattttatga ctagcttagc
      841 tagcgcaaag gtgattttac ttgagcttat catgatttta tttttatcag gagttctctt
      901 tgtttcattc atgagaatga tgtggtactc catgtatatt tctcaaggaa attatgcagt
      961 agatacttta gaggcgcttt acgaagatat gcaaaaagac aaattagtgc atggtaatat
     1021 caataatttt aaaaactata atatagaatt tgagaatgtt agctttgctt ataatgataa
     1081 agctgtcatt gaaaatttat cctttaattt agaagaagga aagtcctacg cacttgtcgg
     1141 ttcatctgga tcaggcaaat caacagtagc aaaacttata tcaggttttt ataatgttaa
     1201 taaaggaagc ataaagatag gcgggatagc aataagtgaa tattctgacg aagccttaat
     1261 taaagccatt tcctttgttt ttcaagattc aaaattattc aagaagagca tttatgataa
     1321 tgtagcttta gctaataaag atgcgacgaa agatgacgtt atgagagcct taaaattagc
     1381 aggatgcgat ttaatattag acaaattccc agaaagagaa aatacaatca taggctcaaa
     1441 aggtgtttat ttatccggtg gagaaaaaca aagaattgca attgctagag caattttaaa
     1501 ggattccaaa attattatta tggatgaagc atcagcatct attgacccag ataacgagtt
     1561 tgaattgcaa aaagctttta aaaatcttat gaaggataaa acagttatca tgattgcaca
     1621 caggctatct acaattaaag accttgatga aattattgtc atggatagtg gaaaaattat
     1681 agaaagaggg tctgacaaag aattaatgtc aaaagataca aggtataaga gcctgcaaga
     1741 gatgtttaac agtgcgaatg aatggagggt ttcaaatgaa agagttttat aaaaaaagat
     1801 ttgctcttac agatggagga gcaagaaatt taagtaaagc aacactggct tcatttttcg
     1861 tttattgtat aaacatgctt cctgccatat tacttatgat ttttgctcag gaagttttgg
     1921 aaaatatggg caaaagcaat ggcttttata tagtattctc agttttgact ttgatagcaa
     1981 tgtatatttt gctttctatc gaatacgata aattatataa cacaacctat caagaaagtg
     2041 cagatttaag aataaggaca gcggagaatt tatcaaaatt acctctatct tacttttcta
     2101 aacatgacat ttccgacatt tcacaaacaa tcatggctga tattgaaggc atagagcatg
     2161 caatgagcca ctcaatacca aaggtgggcg gcatggtact gtttttccca ttaatatctg
     2221 taatgatgct agcgggcaat gtcaagatgg gtttagctgt aattattcca tctattttaa
     2281 gctttatatt tataccttta tctaaaaaat atcaggttaa tggacagaat agatattatg
     2341 atgtcttaag aaaaaactca gaaagctttc aagaaaatat cgaaatgcaa atggagatta
     2401 aagcatataa tttatcgaag gatattaaag atgacttata taaaaaaatg gaagatagtg
     2461 agagagtaca cttaaaagcg gaagtaacta caattttaac tttgtctata tcttcaatat
     2521 ttagctttat atctcttgct gttgtgatat ttgtcggcgt aaatctaatt attaataaag
     2581 agataaattc tctctacctt ataggatatt tactagctgc tatgaagata aaagactctt
     2641 tagatgcatc taaagagggc ttgatggaaa tattttattt atcgcccaaa atagaaagat
     2701 taaaagaaat tcaaaatcaa gatttacaag aaggcgatga ctatagctta aaaaaatttg
     2761 atattgatct aaaagatgtt gagtttgcct acaataaaga cgcaaaagtt ttaaatggtg
     2821 taagttttaa agctaagcag ggagaggtca ctgctttggt aggtgcaagt ggctgcggta
     2881 aaacaactat cttgaaactt atatcaagac tttatgatta tgacaaggga caaatcttaa
     2941 tcgatggcaa agatataaaa gaaatatcaa cagaatctct ttttgataag gtctctatag
     3001 ttttccaaga tgtggttctc tttaatcaaa gcgttatgga aaatattaga atcggaaagc
     3061 aagatgcaag tgacgaagag gttaaaagag cagcaaaact tgcaaattgc acagatttta
     3121 tagaaaaaat ggataaaggt ttcgatacag ttattggtga gaacggagct gagctatcag
     3181 gaggagaaag acaaagatta tcaatagcca gagccttctt aaaagatgcg ccgatattga
     3241 tcttagatga gataacagca agccttgatg ttaacaacga gaaaaagatt caagagtctt
     3301 taaataattt agttaaagat aaaactgttg taatcatttc acatagaatg aaatccatag
     3361 aaaatgcaga caagatagta gttcttcaaa acggaagagt agaaagcgaa ggtaagcatg
     3421 aagagctttt acaaaaatca aaaatttaca aaaatttaat agaaaagaca aaaatggcag
     3481 aagaatttat ttattaggag gactacaatg gataataaaa aattaaaagt aaaagattta
     3541 gtaagcatcg gtgtttttgg cgtaatttat tttgccttca tgtttggagt tggtatgatg
     3601 ggcttgattc caatattgtt cttaatatac ccgacagtat tagccatagt tgcaggaact
     3661 gttgttatgt tatttatggc taaggttcaa aagccatggg cactatttat atttggtatg
     3721 atatcaccac ttgtgatgtt tgcagctggt catacctacg tagttgtggt tttatcactt
     3781 atagtaatga taatagcaga attaattaga aagattggta attataattc atttaaatac
     3841 aatatgcttt cttatgcaat cttcagcaca tggatatgta gctctttaat gcaaatgctt
     3901 ttagcaaaag aaaaatatat ggagtggtct ttgatgacga tgggaaaaga ttatgttgat
     3961 gtattagaaa agttaataac ttatccttac atggctttag tagccttagg tgctttctta
     4021 ggaggaattc ttggagcata tataggcaag gctctattga aaaaacactt tgaaaaagca
     4081 ggcattgtat aatgcctact ttttcttcaa atgctccctt taatcccaat ccgatctcta
     4141 agatattagt cgtatttatc acaggcttaa ctgttatgca tagcataaac atccgttttg
     4201 agctggcaat tgtttgtctt attggtattt tgctttattt gaatggatac aaaaaaacac
     4261 ttttcaaatg gattatattg tgtgggatac tttactcctt gcctaatttt atggtgttat
     4321 ctgaattaaa ccctatagtt aagatgtttt tgagtatacc tattgttatt agaatgttta
     4381 ttttaccatt tatggcagca agctttatga taaagacctc ggatgtaggc gcaataattt
     4441 catcgatgga taagcttaag atttcaaaga atgtatccat acctattgcg gttatgttta
     4501 gattcttccc atcttttaag gaggagaaga aaaacatcaa aatagctatg agagtaagag
     4561 ggataaattt taaaaaacca gtcaaatatc ttgaatatgt ttctgtgcca ctactcatta
     4621 tatcatctaa tatatcagat gacattgcaa aagcggcaga aacaaaggca atagaaaatc
     4681 caattgccaa gaccagatac attcgcgtaa agatacagct aattgatttt gtttatgttt
     4741 tagcggttgc tggacttatt gtgggaggct taatatggtt gaaataaaaa atttaagtct
     4801 tgattatggt gaagagcata tattagatga tatatcacta tccatagccg agggagagtg
     4861 cgtgctattt acaggaaaaa gtggaaatgg taagtcatct ttaataaatt caatcaatgg
     4921 actagctgta aggtatgaca acgcaaagac aaagggcgaa ataattattg atggtaagaa
     4981 tataaaaaat ttggaacttt atcaaatctc aatgcttgtt tcaactgttt ttcaaaatcc
     5041 taagacatat ttttttaatg tcaatacgac attagaatta ttattttatt tggaaaatat
     5101 cggtcttgca agagaagaga tggacaggcg tttgaaggat atgcttgaga tattcccgat
     5161 aaaaaatctt ttgaacagaa atatatttaa tctatccggc ggtgaaaaac aaattctttg
     5221 cattgcagct tcttatatag caggtacaaa gattatagtt atggatgagc cttcatcgaa
     5281 tttagatatt aaaagcataa gtgttttggc aaagatgcta aagatattaa aagagaaagg
     5341 cataagcata attgttgcag agcatagaat tt
//
LOCUS       DAVLTT010000092         5021 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLTT010000092 DAVLTT010000000
VERSION     DAVLTT010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5021
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.092"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            109..1275
                     /locus_tag="VYN15_001985"
     CDS             109..1275
                     /locus_tag="VYN15_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV1453244.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            1414..1740
                     /locus_tag="VYN15_001986"
     CDS             1414..1740
                     /locus_tag="VYN15_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1453245.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            1727..2320
                     /locus_tag="VYN15_001987"
     CDS             1727..2320
                     /locus_tag="VYN15_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV1453246.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            2313..3224
                     /locus_tag="VYN15_001988"
     CDS             2313..3224
                     /locus_tag="VYN15_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV1453247.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDFITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTKLSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            3286..4350
                     /locus_tag="VYN15_001989"
     CDS             3286..4350
                     /locus_tag="VYN15_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453248.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADFDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEESDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKFETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(4587..4784)
                     /locus_tag="VYN15_001990"
     CDS             complement(4587..4784)
                     /locus_tag="VYN15_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter ATP-binding protein"
                     /protein_id="HEV1453249.1"
                     /translation="MRSLSQEKDIYSFDEPTGNLDRNSTELFLNEVEKLVNEEKIVIV
                     VTHDKDVIARASKVINMDEFH"
BASE COUNT         1462 a         1153 c          863 g         1543 t
ORIGIN      
        1 tttcaagact ttcccatttt tatcttgaaa gccagaaacc ttacttgaca ttatagtgaa
       61 aaagccttaa aataagctgt tattaaaatc agctagaaga ggtattatat gaaaaagcaa
      121 tcactctttt ttgttccagg tattatcctg attggtgttt ccttgcgaac tccttttact
      181 gttttaccca ttattttggg aaatatttcg caaggtctgg aggtagaagt tagttcgctt
      241 ggtgtcttga ccagcctgcc tctccttatg tttaccctct tttcaccatt ttctacccaa
      301 ctggctcaga aaatcggctt ggagcatctc ttcacctaca gcctcttctt cttgaccatc
      361 ggctcactta ttcgactaat caatctgccc ctgctctatc taggaacctt gatggttggg
      421 gcaagtgtcg cagtcatcaa tgtcctgctt cctagtctta tccaagccaa tcaaccaaag
      481 aaaattggtt ttctgaccac cttatatgta acgtctatgg ggattgcaac ggctctggct
      541 tcctatctag ctgtgcccat tacacaagcc agttcttgga aaggacttat ccttctcctc
      601 acgttactct gtctagcaac ttttttggtc tggctcccaa atcaccgcta taatcataga
      661 ctagctccac aaaccaaaca aaaaagtcaa ataaaggtca tgcgtaataa acaggtttgg
      721 gcaattatta tcttttcagg ttttcaatcc ttgatctttt acaccgtcat gacctggtta
      781 cctaccatgt ctatccatgc aggtctatcc agtcacgaag ctggcttgct gacttctatc
      841 ttatctctga ttagcattcc tttttcaatg accatcccaa gcctgacaac cagtttatct
      901 actcgcaacc gtcagctcat gctcactctg gtttcactag ctggtgtggt cggcatttcc
      961 atgctctttt tcccaatcaa taatttcatt tactggcttg ccatccatct cctcatcgga
     1021 accgcaacca gcgccctctt cccttatctc atggtcaact tttcactcaa gacaagcgcc
     1081 cctgaaaaga cagcccaatt gtccggccta tctcaaacag gaggctatat cctagcagcc
     1141 tttgggccaa ccctctttgg ttacagtttt gacctgttcc actcttgggt accagctgta
     1201 gctgccctct tgctcatcga tatcctgatg actgtggccc tctttacagt ggacagagcg
     1261 gataagatcc tttaaacttc tagttttagc tagaagtttt ttatatataa aaattttaca
     1321 catttctctt gacagggctt tcttttagat gtacaatgta tgtgtagaaa aattatatat
     1381 aaaaatctta cacattagaa aaggaggttt cccatgtact ttccaacatc ctctgccttg
     1441 attgaatttc tcatcttggc cgtactggag cagggtgatt cttatggtta tgagattagc
     1501 caaaccatta agctaatcgc taatatcaaa gaatccacac tctatcccat tctcaaaaaa
     1561 ttggaaggca atagctttct gacaacctat tctagagagt tccaaggtcg catgcgcaaa
     1621 tactactcct tgacaaacgg tggtatagag cagctcttga ccctaaaaga tgaatgggca
     1681 ctctatacag acaccatcaa tggcatcata gaagggagta tccgccatga caagaactga
     1741 atacctgact cagctagaac tctatctcaa gaaactacct gaagctgacc gtatcgaagc
     1801 catggactat ttcagagagc tctttgacga tgctggagtc gaaggagaag aagaactcat
     1861 cgctagtttg ggaactccca aagaagcggc ccacgaagtt ctatccaatc ttctcgataa
     1921 aaaaatcaat gaagcacccg ctcaaaaaaa taaccgacaa attttacata tcgccttgtt
     1981 agccctcctt gcagcaccta tcggcattcc tctgggaatc gccatcctcg tgaccctgtt
     2041 cgcaatcctt gtagccgctt tgactgtcat tctggctttc tttgcagttt ccatactggg
     2101 tatcatcggc ggattcctat ttttagttga aagtttcact atcctcgccc aagccaaatc
     2161 agcctttatc ttgatttttg gttctggttt actggctatc ggtgcttctt cgctagtttt
     2221 acttggcatt tcctatgtag ctcgcttctt cggtctactc attgttcgtc tggtacaatt
     2281 tgttcttaaa aaaggaaaga gaggtaatca gcatgcgtaa atggacaaaa ggatttctca
     2341 tctttggtgt ggtgactacc gttatcggct ttatcctgct ttttgtaggt atccaatctg
     2401 acgggattaa gagcctactt tccatgtcca aagaacctgt ctatgatagc cgtacggaaa
     2461 agctaacctt tggcaaggaa gtcgaaaacc tagaaattac tctccaccaa cacacgctca
     2521 ccatcacaga ctctttcgat gatcaaatcc acatttctta ccatccatct ctttctgctc
     2581 accatgattt tatcaccaat cagaacgata gaactctgag tctcactgat aagaaactgt
     2641 ctgaaactcc gtttctctct tctggaattg gtgggattct tcatatcgca agtagctact
     2701 ctagtcgttt tgaagaagtt attctccgac taccaaaagg gagaactcta aaagggatca
     2761 acatctcagc caatcgcgga caaaccacca tcataaatgc tagccttgaa aatgcgaccc
     2821 tcaatacaaa cagctatatc ctccgaattg aaggaagtcg tatcaaaaac agtaaactca
     2881 caacgcccaa tatcgttaat atctttgata cagttcttac agatagtcag ctagagtcaa
     2941 cagataatca cttccacgct gaaaatatcc aagtccatgg taaggttgaa ctgactgcca
     3001 aagattatct cagaatcatc ctagaccaga aagaaagcca acgaattaac tgggacatct
     3061 caagtaacta cggttctatc ttccaattca caagagaaaa gcctgaatca agaggtacga
     3121 aattaagcaa cccttacaaa actgaaaaaa ccgatgtcaa ggatcaactc attgcgagat
     3181 ctgatgataa tattgatcta atatccacac caagcagacg ttgacaaaaa cgcttacatc
     3241 tgctactatg gaagcatatt tatctaacca aaaggaggtt ctaccatgaa acaagaatgg
     3301 tttgaaagta atgattttgt aaaaacaaca agcaagaaca agcctgaaga gcaagctcaa
     3361 gaggttgcag acaaggctga agaaacgata gccgatttcg atacaccaat tggaaaaaat
     3421 actcaagtag aggaggaagt ctctcaagct gaagtcgaac tggaaagcca gcaagaagag
     3481 aaaattgaaa ctcctgaagt cggtgaagcg agaacagaaa tagaagaaaa gaaggcatct
     3541 aattctactg aagaagagtc agacctttct aaagaaacag aaaaagtcac tatagctgaa
     3601 gagagccaag aagctcttcc tcagcaaaaa gcaaccacga aagagccact tcttatcagt
     3661 aaatctttag aaagtcctta tatccccgac caagctccaa aatctaggga taaatggaaa
     3721 gagcaagtgc ttgatttttg gtcttggcta gtggaagcga tcaaatctcc tacaagtaag
     3781 tttgaaacaa gtatcacaca cagttacaca gcctttctct tgctcattct gttttctgca
     3841 tcttcctttt tctttagtat ctatcacatc aaacatgctt actatggaca tatagcaagc
     3901 attaacagtc gcttccctga gcagctagct cctttaactc ttttttctat catctctatc
     3961 ctagtagcga caacactctt cttcttttca ttcctcttgg gtagtttcgt tgtgagacga
     4021 tttatccacc aggaaaagga ctggacgcta gacaaggttc tccaacaata tagtcaactc
     4081 ttggcaattc caatcttcct cactgctatt gctagtttct ttgctttctt tgatagccta
     4141 cgatttacag ctctcttgtg tgtgattagc attggaatca ttctgcttgc cagtctccat
     4201 atcattacaa gaccaagtca agcaagtgaa accgactcct tctatcaatt attcttgtct
     4261 gtccttgtga acggagttat tatcctcctc ttctttgtag ctgaagtggc actgattgga
     4321 gattatcttc gtatcttggc ctttctttaa aattcaatcc tgtcatcctt ggcaggattt
     4381 tttctatgtc aaaaaagcaa gtcgattgac ctgcttctgc tttacttttc ttgtgctaat
     4441 gttttaaaat cttgtcctag gatgggtttt attcctagag ttcaaagtat gatagcgttg
     4501 ctataaagtt cgttattcca aatattatgc aaactagtta tatgtaaaat taagattaga
     4561 aaccaccaat ctccatttat taacttttaa tgaaattcgt ccatattaat aactttactt
     4621 gctctagcaa taacatcctt gtcatgagtc acgacaataa caatcttttc ctcgttcact
     4681 aatttctcaa cctcgtttag aaataattca gttgagtttc tgtccaaatt tcctgtaggc
     4741 tcatcgaatg aatagatatc cttttcttgc gataaactcc tcatgaatag aattttttgt
     4801 ttctgacctt acgaaatatt ggtggctttc ccatcaatct gatgactcag agctatattg
     4861 agattcaaac tatcaagatt atttgattca tagttttcct tatcaaatag ggtgaaatta
     4921 atattttttg tcatgcttca tcacctccag atatagtatt aaaattttag atcagttgac
     4981 tatccgtgtc gaatctttca tagaaactct tgttattata g
//
LOCUS       DAVLTT010000093         4553 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLTT010000093 DAVLTT010000000
VERSION     DAVLTT010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4553
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.093"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..597
                     /locus_tag="VYN15_001991"
     CDS             <1..597
                     /locus_tag="VYN15_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1453250.1"
                     /translation="ASASASTSASESASTSASASASTSASASASTSASASASTSASAS
                     ASTSASASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASAS
                     TSASASASTSASESASTSASASASTSASASASTSVSNSANHSNSQVGNTSGSTGKSQK
                     ELPNTGTESSIGSVLLGVLAAVTGIGLVAKRRKRDEEE"
     gene            658..2742
                     /locus_tag="VYN15_001992"
     CDS             658..2742
                     /locus_tag="VYN15_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1453251.1"
                     /translation="MDDKITVIVPVYNVENYLRKCLDSIITQTYKNIEIVVVNDGSTD
                     ASGEICKEFAEMDHRITYIEQENAGLSAARNTGLNNMSGNYVTFVDSDDWIELDYVET
                     LYKKITEYQADIAVGNYYSFNESEGMFYFHISGDSYYEKVYDNVSIFENLYETQEMRS
                     FALISAWGKLYKARLFEQLRFDIGKLGEDGYLNQKVYLLSEKVIYLNKSLYAYPIRKG
                     SLSRIWTEKWMHALVDAMSERITLLANMGYPLEKHLAIYRQMLEFSLSNGQASGLSDT
                     ATYKEFEMKQRLLNQLSRQEESEKKAIVLAANYAYVDQVLTTIKSICYHNRSIRFYLI
                     HSDFPNEWIKQLNKRLEKFDSEIINCRVTSEQISCYKSDISYTVFLRYFIADFVQEDK
                     ALYLDCDLVVTKNMDDLFATDLQGYPLAAVRDFGGRAYFGQEIFNAGVLLVNNAFWKK
                     ENMTQKLIDLTNEWHNKVDQADQSILNMLFEHKWLELDFDYNHIVIHKQFADYQLPEG
                     QDYPAIIHYLSHRKPWKDLAAQTYREVWWYYHGLEWTELGQNHHLHPLQRSHIYPIKE
                     PFTCLIYTASDHIEQIETLVQSLPDIQFKIAARVIVSDRLAQMTIYPNVTIFNGIHYL
                     VDVDNELVETSQVLLDINHGEKTEEILDQFANLGKPILSFENTKTYEVGQEAYAVDQV
                     QAMIEKLREISK"
     gene            2739..3617
                     /locus_tag="VYN15_001993"
     CDS             2739..3617
                     /locus_tag="VYN15_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HEV1453252.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLSNICFHIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVICRNFENFHVSSGKLILHDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLVVKRRD"
     gene            3657..4531
                     /locus_tag="VYN15_001994"
                     /pseudo
     CDS             3657..4531
                     /locus_tag="VYN15_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752824.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
BASE COUNT         1475 a          736 c          963 g         1379 t
ORIGIN      
        1 gcttcagctt cagcatcaac gagtgcgtct gaatccgcat caacgtctgc ctcagcctca
       61 gcgtcaacca gtgcctcagc ctcagcatcg acaagcgcct cagcttcagc atcaacgagt
      121 gcgtcggctt cagcaagtac aagtgcgtcg gcttcagcaa gtacaagtgc gtctgagtca
      181 gcatcgacaa gcgcttcagc ttcagcatca acgagtgcgt cggcttcagc aagtacaagt
      241 gcgtcggctt cagcaagcac aagtgcatca gcttcagcaa gcacaagcgc ctcggcttcc
      301 gcatcaacga gtgcttcagc ttcagcaagc acctcagctt ctgaatcggc atcaacgagt
      361 gcctcagctt cagcgtcaac cagtgcttcg gcttcagcaa gtacatcagt ttcaaattca
      421 gcaaaccatt cgaactcaca agttggaaat acttctggat cgacaggtaa atcccaaaaa
      481 gaattgccta atacaggtac tgagtcgtca attggatctg tgttacttgg agttctagca
      541 gctgttacag gtattggatt ggttgcgaaa cgccgtaaac gtgatgaaga agagtaagac
      601 aacctgtaaa gttaggctaa actaactcgc gcacataaat caaggagaaa attgctagtg
      661 gatgataaaa taacggtcat tgtaccagta tacaatgtgg aaaactatct gaggaagtgc
      721 ctagatagta ttattactca aacatataaa aatattgaga ttgttgtcgt taatgatggt
      781 tctacggatg cttcaggtga aatttgtaaa gaatttgcag aaatggatca ccgaattacc
      841 tatatagaac aagaaaatgc tgggctgtca gctgcacgaa acaccggtct gaataatatg
      901 tccggaaatt atgtgacctt tgtggattca gatgattgga ttgagttaga ttatgtagaa
      961 accctatata aaaaaataac agaatatcaa gctgatattg cagttgggaa ttactattct
     1021 ttcaacgaaa gtgaaggaat gttctacttt catatatcag gagactccta ttatgagaag
     1081 gtatatgaca atgtttccat ctttgagaat ttgtatgaaa ctcaagaaat gaggagtttc
     1141 gctttgatat ctgcttgggg taaactctat aaggcgagat tgtttgagca gttgcgcttt
     1201 gacataggta aattaggaga agatggttac ctcaatcaaa aggtatattt attatcagaa
     1261 aaggtaattt atttaaataa aagtctttat gcttatccta ttagaaaagg tagtctatca
     1321 agaatttgga cagaaaagtg gatgcatgca ttggttgatg ccatgtccga acgcattacg
     1381 ctactagcta atatgggtta ccctttagaa aagcatttgg cgatttatcg tcaaatgttg
     1441 gaattcagtc tctccaacgg tcaagctagc ggtttatctg acacagcaac atataaagag
     1501 tttgaaatga aacaaaggct tttaaatcag ctatcgagac aagaggaaag tgaaaagaaa
     1561 gccattgtcc tagcagcaaa ttatgcctat gtagaccaag ttttaacgac aatcaagtct
     1621 atttgttatc ataatcgttc gattcgtttt tatctgattc atagcgattt tccaaatgaa
     1681 tggattaagc aattaaataa gcgcttagag aagtttgact cagaaattat taattgtcgg
     1741 gtaacttctg agcaaatttc atgttataaa tcggatatta gttacacagt ctttttacgc
     1801 tatttcatag ctgatttcgt gcaagaagac aaggccctct acttggactg tgatctagtt
     1861 gtaacgaaaa atatggacga cttgtttgct acagacttac aaggttatcc tttggctgct
     1921 gttagagatt ttgggggcag agcttatttt ggtcaagaaa tctttaatgc cggtgttctc
     1981 ttggtaaaca atgctttttg gaaaaaagag aatatgaccc aaaaattaat tgatttgact
     2041 aatgaatggc ataataaggt ggatcaggca gatcagagca tcttgaatat gctttttgaa
     2101 cataaatggt tggaattgga ctttgattat aatcatattg tcattcataa acagttcgct
     2161 gattatcaat tgcctgaggg tcaggattat cctgctatta ttcactatct ttctcatcgg
     2221 aaaccgtgga aagatttggc ggcccaaact tatcgtgaag tttggtggta ctatcatggg
     2281 cttgaatgga cagaattggg acaaaaccat catttacatc cattacaaag atctcacatc
     2341 tatccaataa aggaaccttt cacttgtcta atctatactg cctcagacca tattgaacaa
     2401 attgagacat tggttcaatc cttgcctgat attcagttta agatagcagc tagagtaata
     2461 gttagtgatc gattggctca gatgacaatt tatccaaacg tgactatatt taacggaatt
     2521 cactatttgg tagatgtcga taatgaattg gtagaaacca gtcaagtact tttagatatt
     2581 aatcatggcg aaaagacaga agaaattctc gatcaatttg ctaatcttgg caagcctatc
     2641 ttatcctttg aaaatactaa aacctatgaa gtaggtcagg aggcatatgc tgttgaccaa
     2701 gttcaagcaa tgattgagaa attaagagaa ataagcaaat gaagaaaaat catttagtag
     2761 gagatgctct gattttgacg gttagtgatc agattgaaga gttggattat ctccttgaat
     2821 ccttgtcaaa tatctgtttt catattgcag cacctgttca attttccgag aaaatccgta
     2881 gcttagaaac gaactataat gtccgtctcc gaacgattac aaatgaagaa cagctaaact
     2941 ttctagtcga tacctgtgac tttttactag atatcaatca ctttcaagaa gtagatgcta
     3001 ttgtctccaa gtttgtacag gctggaaaat ctgtctttgc atttgacaat acagtccatg
     3061 gaaatcaggg gcaggaagtt tttctatcaa gtacaccaga caaattggtt tctagagtga
     3121 gagactatct gaatgaagtc agagtaggca ccaatcatca agaaaaaatc atccaagatg
     3181 ggacttggaa tgtctttaaa atcgatgata aggctcactt cattgtagga gccaatgtca
     3241 tctgtagaaa ttttgaaaat tttcatgtct cttctggtaa gttaatactg catgatggtg
     3301 tttttatcaa caactcttgt agttttaact gtatggaaag aattgaaatc ggagctggta
     3361 ccatgatggg agagggtgtt cgtttttatg atcacgacca tatttatact gctgaaaaga
     3421 ttgaaaagtg gcagtggact acagcgccga ttagagttgg cagagactgc tggataggaa
     3481 gtaatgtcac gattttaaaa ggagtgacga ttggggataa taccattatt ggagcaggtt
     3541 gtctcatacg caatgatatt ccatcaaaca gtgtagttta taataatgga aatcttgttg
     3601 taaagagaag agattaagag ggaaatagaa taaatcaagt ctaggaaagt tagtatatgg
     3661 aaaatgaact aattagtatt gtagttccaa tctacaatgt tgagaattat ttgcgaatgt
     3721 gtttggatag cattcagaat cagacgtatc aaaattttga gtgtttatta atcaatgatg
     3781 gctctccaga tcattcatcc aaaatatgtg aagaatttgt agagaaagat tctcgtttca
     3841 aatattttga gaaagcaaac ggcggtcttt catcagctcg taacctaggt attgaatgtt
     3901 cgggggggcg tacattactt ttgtagactc tgatgattgg ttggaatcgg actatttaga
     3961 agtactatat tcaaaaatag tagagtatga tacggatttt gtgataggat catataaaaa
     4021 gtttagtatg tctgataatt gttattatat gcatgtttgg gatcaggatt attatgaaaa
     4081 aatatggact agtcaggaat tgctaactca gctgccaaac cttgaaaatt atgatggttc
     4141 ttacacagtt tcttggggaa aactatttaa acgtttttta tttgacgagg tattatttaa
     4201 cgagcaacgt agatttggtg aggattttga gtgtagtttt aaattgtatt taactatgac
     4261 tagctgctta tatattcata gagcacttta taattataga gtacactcag aatcgatggt
     4321 gggaaaagtt aagacagaga gacaactaat ggatgatgtg gaaatccgac ttggacgaat
     4381 tccttttttg attggaagag gaattgattc gactccttac atagcagaaa ttaagagact
     4441 tattcaatgg cgtttagata cgaaatcaga tgtcgaagaa ggtgagtcaa acgctttgtg
     4501 tatgtatcga gaaatactta ggaatttata ggaaataata tcagtattta aat
//
LOCUS       DAVLTT010000094         4501 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLTT010000094 DAVLTT010000000
VERSION     DAVLTT010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.094"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(282..833)
                     /locus_tag="VYN15_001995"
     CDS             complement(282..833)
                     /locus_tag="VYN15_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1453253.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(1183..2007)
                     /gene="nadE"
                     /locus_tag="VYN15_001996"
     CDS             complement(1183..2007)
                     /gene="nadE"
                     /locus_tag="VYN15_001996"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV1453254.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGCLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYTLAGFHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(2004..3464)
                     /locus_tag="VYN15_001997"
     CDS             complement(2004..3464)
                     /locus_tag="VYN15_001997"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV1453255.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(3580..4068)
                     /locus_tag="VYN15_001998"
     CDS             complement(3580..4068)
                     /locus_tag="VYN15_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453256.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(4058..4267)
                     /locus_tag="VYN15_001999"
     CDS             complement(4058..4267)
                     /locus_tag="VYN15_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1453257.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
BASE COUNT         1281 a         1045 c          834 g         1341 t
ORIGIN      
        1 ctaactcgat agaggattct attttaaatt taacaacagc taggattaca ctataaaaag
       61 tacattacca cctgttcggc tggagaatct agtcgattag ctccctctta gttacaagct
      121 tcaagcgatt ttttaactaa tactaaacca gattaaagaa ggaactagag catctgtctt
      181 gtactaatca atatgctatt ttaaaattgc aaataaactt ggaatgctaa ttattatatt
      241 tacaataaat agttgacttc gatagaaaca gaaaatagaa ttcaacattc ttccctactt
      301 ataccataat aaataagatc cgcaagatag ccttttctct ctacaccatt aacaatggtt
      361 tgtagatagg acattccagc cttttccatg acacggcctg aagctgggtt gagactggca
      421 taacgtgctc tgaccttttg aaaacctgct tgagtaaaac aaaagtccaa gacagctttc
      481 aaggcctctg tcatcatacc atgtccccag taagccttgc ctagcacata gccgatttca
      541 cagcttaaat cagcctcgtc tatcttaacg atgctgatat ctcctatcac ttgctctggg
      601 ttttctttta gacaaatggc ccatttgtaa tagttgagat tagtatagga agcaacccaa
      661 ttgcgaatcg agtttcgagt gatttcgaca tcaggatggg gatcccaggt aacataggtc
      721 agattctcag cggatgaagc ccaattttga aacatggctt ctgcatcact ctccacaaat
      781 cttcttaaaa tcaaacgttc tgtctgtaat atttgcgtac caatagattt catgatgcta
      841 cctcacttcc ttatttctat gctcgtagta aaaaggctca actcagtaac agctagaaaa
      901 cgagtttgtc ttctaatttc ttgacgcagt cgctgcctgg tttgaaatgc gatctagcaa
      961 gctttttcaa acctagtcat cgttgcaggg gtaagacgat gaaatcgaac tcttcgagtt
     1021 accgaatctg cctcattttc ttatttctaa actcggggtt caagatcccc cagaccttct
     1081 ctcactttct tattttaaga tgagaggctg aaaacctcca gtggaggttt ttcttgcttt
     1141 ttaatttcag ggcaagaagc taaaaaggtc ccccggacct ttttactccc aaaagtcatc
     1201 aaatacggtg atgggtaagt ggcgtttgtg ttggcctttg tgccaccagt tttcaatggt
     1261 cgcttgagct tctgggctga ttgttttgcc ttctaggtag tcgtcaatct ctgcgtaggt
     1321 gactccaagt gcgacttcgt cagctaggcc tggtttatct tcttctagat ctgccgttgg
     1381 gattttttca taaagggctg gctctgcgcc aagtttctgc aagagctgtt ttccttggcg
     1441 tttattgagg cggtaaagag ggagaatatc cgcaccgccg tcaccaaact tggtaaagaa
     1501 acctgtgata ttttccgcgg cgtggtctgt tccaatgacc gctccgctat ggaaaccagc
     1561 aagggtatac tgagcaatca tacggcaacg tgccttgata ttccccttgt tgaagtctga
     1621 aacaggacta cctgtcgctt caactgcagc tgtcatggca tcagctgatt ccttgatatt
     1681 cacaaccaag ctgacatctg gctggatgaa ggctagggct ttttgagcat ctgcttcatc
     1741 agcttgcact ccgtatggca ggcggacagc gataaatttg tagctatcgt ctcccgtttc
     1801 agctcgcagt tcttccatag ctaattgcgc caaacatcct gccaaggttg agtcttgtcc
     1861 cccagaaatc cctagtacaa aggtttttag gaagggatgt tttttcagat atctttttaa
     1921 gaaatcaata gaacgacgga tttcttcctg ggcatcaatc actggtttga cacccagctc
     1981 ttggataatc gtttcttgca aactcattct tcttctcctt caccaagggc ttccttgcgc
     2041 atcttatcaa tcaagtccat cttatcttgc catacatcac gcgccaaatc cactggatag
     2101 tgctgcggat tgagcacacg cttatactca tcccacaact tgtcaaattc cttacgggca
     2161 taatcctgaa tgtcagtcaa actaggcaag ttgtaaacta atattccttc tttgaagata
     2221 tccaccaaga gaggaacggc atcaaaatta cgaaccgtct tcttgatgta tgtataggtc
     2281 ggatgaaaca tcttgatttc tgtcatgtcg ctaatatcca caccatcata agtgatatag
     2341 tcgccttctg acttgccttt ttcacgactg gtaatgcgcc acacctgctt cttacctggc
     2401 gtagaaactt tttcagcatt attagacagc ttaatcgtat tgcgcatctg accagtttca
     2461 tcttcgattg caacaatctt gtaaactgca ccaagagctg gctggtcata agctgtaatc
     2521 agcttggtac ccacgcccca gacatcaatc ttggcctttt gcatcttgag gttaaggatg
     2581 gtattttcat ctagatcatt agaagcataa atcttagcct ctgtaaatcc agcctcatcc
     2641 agttgctgac ggactttctt agaaatgtag gcaatatccc cagagtcaat ccgcacaccc
     2701 ataaagttaa tctgatcacc cagctcacgc gccacctgaa tggcagctgg tacaccgatg
     2761 cgaagggtgt cataggtatc cacaagaaag acacaatttt tgtgggtcgc agcgtaagcc
     2821 ttgaaagctt catagtcatt gccataaacc tgtaccaagg catgggcatg ggttcccaaa
     2881 acaggaatgt caaagagctt acccgcacgc acgttgctgg ttccattggc cccaccaatc
     2941 accgctgcgc gtgttcccca gatggccgca tccatttctt gagcccgacg tgtcccaaac
     3001 tccatcaagg gttcatcttc gataaccgaa cgaatacgag ctgccttcgt cgccaccaag
     3061 gtctggtagt tgacgatgtt caaaagagcc gtttcgacca actgacattg ggctagaggt
     3121 ccttccacct gcacaatcgg ttcattagca aaaaccaaat ccccttcttg ggcagaacga
     3181 acggtcaact ccaacttgaa attgcgaagg taatccaaga acgccccatg ataaccaagc
     3241 gactccaaat aggctatatc actatctgaa aaacgcaagt cttcaagata gttcacaatt
     3301 ctttccaaac ctgcaaaaac cgcatagccg ttcttaaaag gctgttggcg gaaatacacc
     3361 tcaaagaccg ccttcttatt gtgaatccct tggtcaaagt aaacctgcat catgttgatc
     3421 tggtacaagt ccgtgtgcaa tgtcaaacta tcatctggat acatactttt cctacttcct
     3481 tagctagaaa cccatgaaaa ttttcaagaa ctttcatgta ttccaataaa ttagtactat
     3541 tatatcacat tttagctgga ttgagaaaag agtaacaagc tattctccac tctccaattc
     3601 atccatatct tgttcaaatt ttttctgagc ccattcgcca tagctcttaa gaccaagatt
     3661 gccaataaag acccacggaa ggtaaatgac ataagtaatg acccaagcag acaggtattt
     3721 aaaattcaaa ggattgtgct gataaatttc tatgttgaat tgataattct gcaacatcaa
     3781 aagagccgta atagccaagg ttaggaaaaa acaacccaaa atcgtaaaat gaaaacgact
     3841 atagtaggtc actcccagat aacgggcgcg attgaaaaag taaaatgtcc ctatgatgat
     3901 aacgattagc agcatattag aattaaaaag gcttggtgct aatactgaaa tgatataaga
     3961 taggagcgac aaagcaatgc agatatagaa actttcagag cccgctttat tgaacagttg
     4021 ttcttctctt tcgtctagta attgataata ataaaatcta tttttcatct tcttcctccc
     4081 aaaatagttg gtctagggtt ttccctaaac atctgcaaat agactggcag agcgagagac
     4141 tgggattgta ttttcccgcc tctatcaaac caatagtctg gcgtgtcacc ccgacagcct
     4201 ctgccagttg accttgtgtt aaatcacgct ctacccgagc taattttaat tttaaatttt
     4261 tagccacctt cgtcctcctt atagttttaa tactcatcta ctcttaaaaa atccaaaacc
     4321 aacacaagct atcagctatt tattataacc ccattaattt gcactccagt attatcttca
     4381 gccgaaaatc agtattttag gttgtttgaa ataaacttcc tagtttactc ttttattttt
     4441 atttagtatt agctttagta ggatctttta aacgagtttt tattgcttat atttcttgtt
     4501 t
//
LOCUS       DAVLTT010000095         4277 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLTT010000095 DAVLTT010000000
VERSION     DAVLTT010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.095"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            720..1712
                     /locus_tag="VYN15_002000"
     CDS             720..1712
                     /locus_tag="VYN15_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1453258.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VYN15_002001"
     CDS             1714..2532
                     /locus_tag="VYN15_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV1453259.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VYN15_002002"
     CDS             2534..3319
                     /locus_tag="VYN15_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1453260.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLILISLVFFVISLKLWDKGLDSYESAGS"
     gene            3417..3635
                     /locus_tag="VYN15_002003"
     CDS             3417..3635
                     /locus_tag="VYN15_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV1453261.1"
                     /translation="MKDLPEWFGIPESTQTYIEGTTTLQVWTAYQESDLTGFVSLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3620..3766
                     /locus_tag="VYN15_002004"
     CDS             3620..3766
                     /locus_tag="VYN15_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1453262.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFP"
     gene            complement(4100..>4277)
                     /locus_tag="VYN15_002005"
     CDS             complement(4100..>4277)
                     /locus_tag="VYN15_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453263.1"
                     /translation="KIKEQTRKLAAGCSKHCFEVVDRTDVVSNHTHGKATLTWFEEIF
                     EEYKSKTFVNRDTL"
BASE COUNT         1183 a          743 c          918 g         1433 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat tgatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cgatgcgtga gtttataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aatttcacaa tccataggca aacgcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagcaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccagact cgctctttca taagcgtatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgacg gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctgtc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtcattt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggggagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccga aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatatt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagga acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaggc agttgtcgct gagattttga
     3421 aggatttgcc agaatggttt ggaatcccag aaagcacaca aacctatata gaaggaacca
     3481 cgacactgca agtttggacc gcctatcagg agagtgattt gactggattt gtaagcttat
     3541 cctattcgag tgaagattgt gcagagattg attgtctcgg cgtaaaaaag cttatcaagg
     3601 tagaaaaatt gggagccaat tgcttgctac tttagagagt gaagctcgta aaaaagttgg
     3661 ttatctgcag gtcaaaacag tggcagaagc ttctaataaa gattatgatc gaacaaatga
     3721 cttttatcga ggtcttggct ttaaaaagtt agagattttt ccttaactat ggaatccgca
     3781 aaatccttgt cagattttga ttaaaaagct tgaataatat tacttgacat ctatttttta
     3841 ttctcagagt gctatactgt aagtgtaatc gccgatttag ctcagttggt agagcaaggc
     3901 actcgtaaag cctaggttat aggtagataa acgactgagg agttgaaaaa atagataggt
     3961 agaagataac cgttaagcct tactcttagc ggttatttat attgtttaat agcgctaata
     4021 tttcatcaat tatgcctgtt ttcgtgtttc tggtagttgt tcaagtttat tgctactatt
     4081 tttgatggta tgaatgtgct tataatgtat cccggttaac gaaagttttg gacttatact
     4141 cttcgaaaat ctcttcaaac cacgtcaacg tcgccttgcc gtgcgtatgg ttactgacta
     4201 cgtcagttct atccacaacc tcaaaacagt gttttgagca acctgcggct agtttcctag
     4261 tttgctcttt gattttc
//
LOCUS       DAVLTT010000096         4250 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLTT010000096 DAVLTT010000000
VERSION     DAVLTT010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4250
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.096"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..261
                     /locus_tag="VYN15_002006"
     CDS             <1..261
                     /locus_tag="VYN15_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453264.1"
                     /translation="KVGFLGIIYDNEALRDLSKQYLNKNISELQDGSFEGGIQDAVAS
                     KQIVVINEFIACLNSRCVPSQYDRFFYKDRPYIFSRKSPIKG"
     gene            576..1553
                     /locus_tag="VYN15_002007"
     CDS             576..1553
                     /locus_tag="VYN15_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453265.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            2024..2398
                     /locus_tag="VYN15_002008"
     CDS             2024..2398
                     /locus_tag="VYN15_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV1453266.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            2606..3508
                     /locus_tag="VYN15_002009"
     CDS             2606..3508
                     /locus_tag="VYN15_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453267.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFVIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            3564..3917
                     /locus_tag="VYN15_002010"
     CDS             3564..3917
                     /locus_tag="VYN15_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1453268.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKSDCQGICAALAMSPGT
                     FIALAGSAVLTKKLINYIKFGGLGGWLIGAAAGVLATAAGKIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            3914..>4250
                     /locus_tag="VYN15_002011"
     CDS             3914..>4250
                     /locus_tag="VYN15_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453269.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLT"
BASE COUNT         1411 a          551 c          760 g         1528 t
ORIGIN      
        1 aaggttggat ttttgggaat catttacgat aatgaagcat taagagattt gtcaaaacaa
       61 tatttaaaca aaaatatttc ggaattacaa gatggttctt tcgagggcgg tatacaagat
      121 gctgttgcct ctaaacaaat agtagttata aatgaattta tagcttgttt aaattccaga
      181 tgcgtgccat cccaatatga tagatttttt tataaagata gaccttatat tttttccaga
      241 aagagtccta ttaaggggtg aaaatttgtt acatttggat taacaagtgt cctagggatt
      301 agaaataact ctagtatagc tagatatttt tgagtaacta gaaatatcat taggctactc
      361 atatgattgc cagaaaagat ggctgatgaa tcttatttat actgttgcag taggcattgt
      421 ctaggataaa taagctatct tgatggggga aattggaata attttagtag aaacattaaa
      481 ggattatgga caagtagcgc aggattaggt gatgcaatgt gctaagttgg cttggtgtta
      541 gcagtagtat tatttaacaa tggaaagtag actaaatgaa aaataagcgt tatttttttg
      601 acacaatttt aatgatttta ctgcttataa gcacgatatt ttgtgtcagc ccagtattta
      661 taaaattgga catcttagga accccctctc atgccatctt aacctttgta ttggcgatac
      721 cgttattcta tattttgtct caatgcttac atactttgct attactagtt tcctcaatct
      781 tttgtaaatt aagaccaatt tatttttatt ttatatttgt gatcattata ggagctagga
      841 aatactatcg aattctcttt caccaactaa tgggatttag tccaggaata gcagtgtttt
      901 ataaggagag tcaaacaact aagaatctgt ttaaatttta ctacttcttg tactttacaa
      961 cactaatttc atactatttt ttctttactt ttgtgtatga caaaccgttg cttttgcctc
     1021 ttattccatt ttctattatc atagcattag tacaaaaact ttatagaatt gagaatcaac
     1081 aattatttct gttaaaatca aaggtactaa caatactgga atctaagaag aattgtgagt
     1141 ttaatcttca ggattatcat gaaatttgga aattgcaatc aaaatctgag ttgccatgcg
     1201 tggctttatc ttatatcagt ttgatcaagc catatctttc agagagcgtg cgtgaacaaa
     1261 ttgatttatt agaagttaag cgatttaaaa aaataaatca tccaatatca ctttatggta
     1321 tgttggatgt tataaaatta aatctatatt tacggcatta taatgaaaaa aataaatatg
     1381 aatcaatgtt aaagaaaatt ttagaggtaa gaccagactt tgttttaatc gagcagaata
     1441 ttgatgatag tttaaatagc tcgcaaccat tatctttatc tttagctatt tcagaaatcc
     1501 aacttttgct tgaagtgtat atagggatca aacatgtttc aattaggaga taaaactaga
     1561 ataacatttg ctattatagg ggcaagttgc atattagtca gtatgtatct tatacctctc
     1621 attaacacgg ataataaatt ttgggaaata cttttattta tattaggtgt attgctaatt
     1681 ggaattgcgt tactaagtca aaaaaaataa attttgtgta agtgagtacg taattattaa
     1741 tattggctgt tttatggtgg aaagcatcca tagcttttcg taaaataatc tgattggcta
     1801 atatttgcag taggtgttgt ctatgataaa gaaacctatc ttgattggat tttagaactg
     1861 ttaagtttca aacaataatt gattttaaac cttaggtaac ctataaaaac aaataaggta
     1921 gagaaaggat atcttatcta ggtagctaag tgataaaaac acagtcgtct atcacttgtt
     1981 aggaaactat cctaactatg cttaataaaa aaggagaaaa taaatggaac tcgtattacc
     2041 aaataattat gttgttcttg agcaagaaga gatgatgtat cttgatgggg gattttctat
     2101 tccgagatgg cctgttgcaa cagccattaa tatagctttt aatggtgttt taggtggagg
     2161 agcaatcagt ctagttagaa attatattcg taattatggt ttgcggcgag ttacaagcgc
     2221 aattgctgga gcagctgcaa gatatgttgg ggtacgagtt gcaaatagag tggcaggatt
     2281 tgcactgtct gctattaatg gatttgcagc ttggatgtca attggcgatg ctattacaac
     2341 aatctgggcc aacaatgatg taaataggag agacccaaat ttaaacgcct tgtggtaact
     2401 agatatgggt attaaaatgg aaaaaatttt tgttattatt ttttttgtat gtctatttat
     2461 atcatccata acttttttag cctatgattt tgttagcgaa gaaataaaaa agttgattat
     2521 ttggattaat gtcgtttttt tgattttaat catagcaatg ataatttatc caaaattaag
     2581 aaaatgataa ggacactgta aaattatgat acgtaaacta atcatttttt tactaatgct
     2641 ccctcttttt gtcttgtggc tagagttgca tgtcctagtg aataacttac tattgaatct
     2701 agaatctccc cttgattttg tgattagtat gagtcttgct ttctgtagtt tgattttatc
     2761 aaaaatagtt ttagacatac tatacgcatt gaaagatttg tacaagaaag aagctcttat
     2821 tacgattttt ccttttattt ttataggcag gaagaaagta aatgtgaggt tctcgcccta
     2881 tttttcattc catcgtaaaa gtttgtcgcc tgatgattta agatctagga ttatatggag
     2941 ttttattctt gaaattgcta ttatcctagt atttatttta aaaattcctt ttgtcatcat
     3001 tatgcttact acaatatttt tttggactat aatggatatc aatcatctcg tttttaataa
     3061 gacggaattt cttttcaatc aaaataaatg ggaaaaagaa gattcgtttg aaagtgattt
     3121 gacaaatacg ttaaaggata aaatacaaaa atcagatctc agttattctg acttaatgtc
     3181 tcttcagctg tatgatgcga tgaatcaatc caccttttta acggatagtg aactttttga
     3241 ggatattctg agtaaaattg aagattctca taacaccctt ctgtgtacag gtcttgtcga
     3301 gttactgctg tatgagattt ctattagtaa caataacaac tggcaagaaa aggttgataa
     3361 aattagaata cagctcatca gaataaatca attagatttt ttctattata caagttggtt
     3421 aaggcaaaat tttgatttct gtatgaatag agagtatcat aaaatgaaat ctcggaaatt
     3481 attactgagt aataaaaaga tagtttaagt tcgtcctatt tgtaaaacaa atgaaacaat
     3541 ttcaactaag gaggagaaaa caaatggaac ttgtattacc aaataattat gttgtgattg
     3601 atgaagaaga aatgatgtat cttgatgggg gggcttattt aagcaagagt gattgtcaag
     3661 gaatttgtgc agctttagct atgagcccag gaacttttat agcattagct ggatctgcag
     3721 ttttaactaa aaaactaata aactatatta agtttggagg tcttggaggc tggcttattg
     3781 gtgcagcagc aggtgtattg gctacagcag caggaaaaat agcttactgt attggatatg
     3841 gtgctcttaa tagaggttgt gatattagcg ggaaccctta tccttgggat ggattcatat
     3901 ctgcgacagt aagatgaata atgtagataa gattcgaaaa atacatatta tcgtatgttg
     3961 gatgtatata tttttatcat tcagggcgat tataaatgac acggagtatt ttttgcttat
     4021 ttttttagct tttatctact caatagtatc actacctcta tattctgtga aaaataaaat
     4081 agtatctatc tgtctagcca taaattcgat tctgttaatg agtttcccca ttttaatcaa
     4141 taagtttttc ccagaaagtt ttttgactta taccgtatta ataagtgttt ttatcctaga
     4201 gttagcaatc tttcatttaa ttggggaaga ttttgctact aaattgacta
//
LOCUS       DAVLTT010000097         3961 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLTT010000097 DAVLTT010000000
VERSION     DAVLTT010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.097"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..567
                     /locus_tag="VYN15_002012"
     CDS             <1..567
                     /locus_tag="VYN15_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1453270.1"
                     /translation="YTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADT
                     NQTEKPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLYKPSTDTEE
                     TEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVETLTGLKSSLLL
                     GTKDNNTISAEVDSLLALLKESQPTPIQ"
     gene            777..3896
                     /gene="phtE"
                     /locus_tag="VYN15_002013"
     CDS             777..3896
                     /gene="phtE"
                     /locus_tag="VYN15_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV1453271.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     GRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1482 a          660 c          778 g         1041 t
ORIGIN      
        1 tatactcttg aggatctttt ggcgactgtc aagtactatg tcgaacatcc aaacgaacgt
       61 ccgcattcag ataatggttt tggtaacgct agcgaccatg ttcaaagaaa caaaaatggt
      121 caagctgata ccaatcaaac ggaaaaacca aacgaggaga aacctcagac agaaaaacct
      181 gaggaagata aggaacatga tgaagtaagt gagccaactc accctgaatc tgatgaaaaa
      241 gagaatcacg ctggtttaaa tccttcagca gataatcttt ataaaccaag cactgatacg
      301 gaagagacag aggaagaagc tgaagatact acagatgagg ctgaaattcc tcaagtagag
      361 cattctgtta ttaacgctaa gatagcagag gcggaggcct tgctagaaaa agtaacagat
      421 tctagtatta gacaaaatgc tgtggagaca ttgactggtc taaaaagtag tcttcttctc
      481 ggaacgaaag ataataacac tatttcagca gaagtagata gtctcttggc tttgttaaaa
      541 gaaagtcaac cgactcctat acagtagtaa aatgaatgga gcatatttta tggagaagta
      601 acctttcgtg ttacttctct tttttagaaa aacgtaacag aaacttgaca aaagtaattt
      661 taaatagtaa actatttact ggttaattaa atggttaaat aaccggttta gaaaactatt
      721 taataaagta aaagaagttg agaaaaaact tcatcattta ttgaaatgag ggatttatga
      781 aattcagtaa aaaatatata gcagctggat cagctgttat cgtatccttg agtctatgtg
      841 cctatgcact aaaccagcat cgttcgcagg aaaataagga caataatcgt gtctcttatg
      901 tagatggcag ccagtcaagt cagaaaagtg aaaacttgac accagaccag gttagccaga
      961 aagaaggaat tcaggccgag caaattgtaa tcaaaattac agatcagggc tatgtaacgt
     1021 cacacggtga ccactatcat tactataatg ggaaagttcc ttatgatgcc ctctttagtg
     1081 aagaactctt gatgaaggat ccaaactatc aacttaaaga cgctgatatt gtcaatgaag
     1141 tcaagggtgg ttatatcatc aaggtcgatg gaaaatatta tgtctacctg aaagatgcag
     1201 ctcatgctga taatgttcga actaaagatg aaatcaatcg tcaaaaacaa gaacatgtca
     1261 aagataatga gaaggttaac tctaatgttg ctgtagcaag gtctcaggga cgatatacga
     1321 caaatgatgg ttatgtcttt aatccagctg atattatcga agatacgggt aatgcttata
     1381 tcgttcctca tggaggtcac tatcactaca ttcccaaaag cgatttatct gctagtgaat
     1441 tagcagcagc taaagcacat ctggctggaa aaaatatgca accgagtcag ttaagctatt
     1501 cttcaacagc tagtgacaat aacacgcaat ctgtagcaaa aggatcaact agcaagccag
     1561 caaataaatc tgaaaatctc cagagtcttt tgaaggaact ctatgattca cctagcgccc
     1621 aacgttacag tgaatcagat ggcctggtct ttgaccctgc taagattatc agtcgtacac
     1681 caaatggagt tgcgattccg catggcgacc attaccactt tattccttac agcaagcttt
     1741 ctgccttaga agaaaagatt gccagaatgg tgcctatcag tggaactggt tctacagttt
     1801 ctacaaatgc aaaacctaat gaagtagtgt ctagtctagg cagtctttca agcaatcctt
     1861 cttctttaac gacaagtaag gagctctctt cagcatctga tggttatatt tttaatccaa
     1921 aagatatcgt tgaagaaacg gctacagctt atattgtaag acatggtgat catttccatt
     1981 acattccaaa atcaaatcaa attgggcaac cgactcttcc aaacaatagt ctagcaacac
     2041 cttctccatc tcttccaatc aatccaggaa cttcacatga gaaacatgaa gaagatggat
     2101 acggatttga tgctaatcgt attatcgctg aagatgaatc aggttttgtc atgagtcacg
     2161 gagaccacaa tcattatttc ttcaagaagg acttgacaga agagcaaatt aaggctgcgc
     2221 aaaaacattt agaggaagtt aaaactagtc ataatggatt agattctttg tcatctcatg
     2281 aacaggatta tccaagtaat gccaaagaaa tgaaagattt agataaaaaa atcgaagaaa
     2341 aaattgctgg cattatgaaa caatatggtg tcaaacgtga aagtattgtc gtgaataaag
     2401 aaaaaaatgc gattatttat ccgcatggag atcaccatca tgcagatccg attgatgaac
     2461 ataaaccggt tggaattggt cattctcaca gtaactatga actgtttaaa cccgaagaag
     2521 gagttgctaa aaaagaaggg aataaagttt atactggaga agaattaacg aatgttgtta
     2581 atttgttaaa aaatagtacg tttaataatc aaaactttac tctagccaat ggtcaaaaac
     2641 gcgtttcttt tagttttccg cctgaattgg agaaaaaatt aggtatcaat atgctagtaa
     2701 aattaataac accagatgga aaagtattgg agaaagtatc tggtaaagta tttggagaag
     2761 gagtagggaa tattgcaaac tttgaattag atcaacctta tttaccagga caaacattta
     2821 agtatactat cgcttcaaaa gattatccag aagtaagtta tgatggtaca tttacagttc
     2881 caacctcttt agcttacaaa atggccagtc aaacgatttt ctatcctttc catgcagggg
     2941 atacttattt aagagtgaac cctcaatttg cagtgcctaa aggaactgat gctttaggca
     3001 gagtgtttga tgaatttcat ggaaatgctt atttagaaaa taactataaa gttggtgaaa
     3061 tcaaattacc gattccgaaa ttaaaccaag gaacaaccag aacggccgga aataaaattc
     3121 ctgtaacctt catggcaaat gcttatttgg acaatcaatc gacttatatt gtggaagtac
     3181 ctatcttgga aaaagaaaat caaactgata aaccaagtat tctaccacaa tttaaaagga
     3241 ataaagcaca agaaaactca aaacttgatg aaaaggtaga agaaccaaag actagtgaga
     3301 aggtagaaaa agaaaaactt tctgaaactg ggaatagtac tagtaattca acgttagaag
     3361 aagttcctac agtggatcct gtacaagaaa aagtagcaaa atttgctgaa agttatggga
     3421 tgaagctaga aaatgtcttg tttaatatgg acggaacaat tgaattatat ttaccatcgg
     3481 gagaagtcat taaaaagaat atggcagatt ttacaggaga agcacctcaa ggaaatggtg
     3541 aaaataaacc atctgaaaat ggaaaagtat ctactggaac agttgagaac caaccaacag
     3601 aaaataaacc agcagattct ttaccagagg caccaaacga aaaacctgta aaaccagaaa
     3661 actcaacgga taatggaatg ttgaatccag aagggaatgt ggggagtgac cctatgttag
     3721 atccagcatt agaggaagct ccagcagtag atcctgtaca agaaaaatta gaaaaattta
     3781 cagctagtta cggattaggc ttagatagtg ttatattcaa tatggatgga acgattgaat
     3841 taagattgcc aagtggagaa gtgataaaaa agaatttatc tgatctcata gcgtaaggaa
     3901 tagcagtaga aaaagtctga atcaaaaatg aagttctctc aaaagttaga aataaaactc
     3961 t
//
LOCUS       DAVLTT010000098         3960 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLTT010000098 DAVLTT010000000
VERSION     DAVLTT010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3960
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.098"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            371..598
                     /locus_tag="VYN15_002014"
     CDS             371..598
                     /locus_tag="VYN15_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453272.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /locus_tag="VYN15_002015"
     CDS             886..3783
                     /locus_tag="VYN15_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEV1453273.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNNQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGNPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDKVVISNLRDNPEAKD
                     PAAPSPLNIDMVLVQDPTTKRIFSIYDMFPEGRAVFGMPKTPEKAYEKIGDKTYQILY
                     KQGESGHYTVRENGEVYNAQNQKTDYRVVVNPTEPGYRDKGNLYKGQELIGNIYFAHS
                     TKNPFRVANTSYLWMSYSDDDGKTWSAPRDITPGLRKDWMKFLGTGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1358 a          635 c          878 g         1089 t
ORIGIN      
        1 gtcagtttca tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaataaggta taataaattt
      241 attaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataatc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga atttaagcca
     1321 gatgccaagg ccccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acagcagaat tgccaaatgg tcgagttcgc
     1561 ctgtatgtta atggtgtttt atctcgaaca agtctgagat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa cccaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg aaagacatgg ggagataagg tggttatctc caatcttcga
     2041 gataatcctg aagctaaaga tcctgctgcg ccatcgcctc taaatattga tatggttttg
     2101 gttcaagacc cgacaacaaa gagaatcttc tcaatttatg atatgttccc agaaggtcga
     2161 gcagtttttg gaatgccaaa aacacctgaa aaagcttatg aaaagatagg ggataaaact
     2221 tatcaaatct tgtataaaca aggagagtct ggtcattata ctgttcgtga gaatggagaa
     2281 gtgtataatg cacaaaatca aaagacggat tatcgtgttg tagtgaatcc aacagaacct
     2341 ggctatagag ataaaggaaa tctttacaaa ggtcaggaat tgattggaaa tatctatttt
     2401 gcacacagta caaaaaatcc atttagagta gccaatacga gctatctatg gatgtcatat
     2461 agtgacgatg atggtaaaac ttggtctgca ccgagagaca ttactccagg tcttcgcaag
     2521 gattggatga agttcctagg aacaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 gaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcacgaagg aaaagaatac atcatcctca gtaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gtatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttgt ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
//
LOCUS       DAVLTT010000099         3923 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLTT010000099 DAVLTT010000000
VERSION     DAVLTT010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3923
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.099"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(329..862)
                     /locus_tag="VYN15_002016"
     CDS             complement(329..862)
                     /locus_tag="VYN15_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV1453274.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(951..1727)
                     /gene="recX"
                     /locus_tag="VYN15_002017"
     CDS             complement(951..1727)
                     /gene="recX"
                     /locus_tag="VYN15_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV1453275.1"
                     /translation="MKITKLEKKKRLYLMELDGQQTSYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            complement(1737..2513)
                     /locus_tag="VYN15_002018"
     CDS             complement(1737..2513)
                     /locus_tag="VYN15_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEV1453276.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQETKIASWFETEGLGTPVIIYLSANKDFLLTKEAIGSNALAFLNQPE
                     RLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2570..>3923
                     /gene="rlmD"
                     /locus_tag="VYN15_002019"
     CDS             2570..>3923
                     /gene="rlmD"
                     /locus_tag="VYN15_002019"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1453277.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKENHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1240 a          684 c          722 g         1277 t
ORIGIN      
        1 taaaatattg tactaaatga ttgatgctat gtggaaatac aaaaaaatgt ttttgatacg
       61 aagttgacct gtatttttta tactaatcat tttcgtattt tttgtattaa acgatataag
      121 tttgttgtaa acttactagg aataaagaca ttaaaaaata atagtatatc tatttgtttt
      181 atatatttta cgaattctgc ataaatctct ttctagtaat gtgttgtaac tctgctataa
      241 tggatttatt cctttttgtg tttacacaat ttattttata ctaccaaaaa aaacaaggtc
      301 aggattttgt tcctgacctt tgacaacttt accgattctt tagttctaca tagcgcttgt
      361 accaaatgtt tacataggct tctgagaaag gaccacgtcc attgttaatc caatcaacaa
      421 gaattttgac atgttctttt aaaatatagt ccaagtcatc agaataattc attttgcgtt
      481 tgtgacgctc gtactcttca acgtccaaga gacgtttttc cccatctgta aaaattttaa
      541 catccaaatc gtaatcaata tacttcagtg cttcttcatc cagatagtag gggctagcca
      601 tattgcaata gtaagaagtt ccattatcac gaatcatggc aatgatatta aaccaatatt
      661 tcttgtgaaa gtaaacaata gccggttctc gagtgaccca acgacgacca tcactttcgg
      721 taacaagtgt atgatcgttg acaccaataa tggcgttttc tgttgttttt agtaccatgg
      781 tgtcccgcca agttcggtgg agactcccat catgcttata actttgaatt gtaataaagt
      841 cgccttcttt tggaagcttc ataactaacc aactttctac aatttataag tttatcattt
      901 actattgtac cataaaatta cctaaaatct gtgaatttca cttggaaata ttaaagatat
      961 tctctaagag cgcttgctat atccgaaaaa tcgtagccct ttcgtgctaa aacttgagtt
     1021 aaacgctgct tcagttcgta tccttcatac tttcgagcat acttactata ttgtttatca
     1081 agttccttga agatgagttc ttgagtcgtt tcttggtcaa cttggctatc taagtcgtca
     1141 aaggcaattt tagcatcaga ataagagaag cccttgttag tcaagttctg gataatctta
     1201 tcttgcaggg cacgagatgg aagttttccc tcatattttt tcaatagttt attagctaca
     1261 cgttgagcaa cttcagaaaa atcaaattct ttcaagttct cttctatagt agattttgaa
     1321 atcccttttt gagctagttt ctgagtcagc acataaggac ccttgtctcc tgaaagttga
     1381 ttggtattga tgatagcata agcgtactga ccatcattaa tccacttatc ttctttaaga
     1441 ttagcaataa cttgagaaac gatgttttta tcaatatcgt attttttcag atattctctg
     1501 acttcttttt cagtgcgtgc tttaaaggat aagtggtaga gagcgagatt cttaccataa
     1561 gaaaactggg caaaatcctg aatctcggtc agttcctctt tactaatgac cttatctcga
     1621 gacagcataa aacggacaat ggtatcttcc gtgatataag aggtttgctg tccatctagt
     1681 tccatcaagt agagacgttt tttcttttca agttttgtga ttttcataat ttcctttcat
     1741 ctaaatgctt cgaaagctgc aacaagtcgt agtttatcca tatttacata ttctctaccg
     1801 taatagtcga gaaataattc agcatacgta gcatcttgta ggttgtaatg aagggaccaa
     1861 attgcccaaa agaggtcgat atgtcggtca ctaaaaccag ccaatcccaa gtcaataaag
     1921 caagaaaaat gagaggcatc cttcaagatg aaatttggca ggcaggcatc tccatgaata
     1981 aaagcatcag ctttgagaat gtaacctttc tcttgtatca gttggtaagc ttcttcacga
     2041 ctgtgaatgt gaaattgagg cagaagagtc ttgttataaa aagtcccctt ctgatagttt
     2101 tttaaggctt tttctttata acgcttcaga tgattttccg acggaaaaga ttgtggttta
     2161 agactgtgaa gtttgtttaa tgcttgagcc agggtttgac agagtctttc gggttgattt
     2221 aaaaaagcga gagcgttgct gccaatggct tctttagtca gaaggaagtc cttatttgct
     2281 gataaataga taatcactgg agttcccaat ccttcagttt cgaaccaact tgcaatctta
     2341 gtttcttgag ctaatctgcc tttttgatct atttttaaat agtaacctga atctatatat
     2401 aggacagttg cacttgaatg agaagaacta tcagagagat tagctccctt gatatagctt
     2461 cgtaattgtt cagggaaatc tagtatacta aagcgaggtg tttttgaatt catgctttta
     2521 ttgtaacata ttcttaaata tcttagaaac tccatggtat aatagacata tgaatctgaa
     2581 agtgaaacaa aaaataccat taaaaatcaa gcgcatggga attaacggtg agggaatcgg
     2641 cttttaccaa aaaacattag tctttgtacc aggagctctc aaaggcgaag atatctattg
     2701 tcagattact tctattagac gcaactttgt tgaagcaaaa ttactgaagg tcaacaagaa
     2761 gtctaaattt cgaattgtgc catcttgtac tatttataat gaatgcggag gctgccaaat
     2821 catgcacctg cattatgata agcagctgga gttcaagacg gacttacttc atcaagcgct
     2881 gaaaaaattt gctcctgcag gatatgaaaa ttatgaaatt cgtccaacta ttggaatgca
     2941 ggaaccaaaa tattacagag ctaagttaca atttcagact cgaaaattta aaaatcaggt
     3001 caaggcgggc ttatatgcac aaaactctca ctatttagta gagttgaaag actgcctggt
     3061 acaagataag gaaacccaag tgattgctaa tcgcttagca gaattactta cttatcacca
     3121 gattccaatc acggatgaga gaaaagttct aggtgtccgt actattatgg tccgacgcgc
     3181 gagaaagacc ggacaggttc agattattat tgttacaaac cgccagctta atttaactca
     3241 attggtaaaa gagttggtta aagatttccc agaagttgtg acagtagctg ttaatacaaa
     3301 tacagctaaa accagtgaga tatatggtga aaagacagag attatctggg ggcaagagag
     3361 tattcaagaa ggtgtactca attatgaatt ttcactatcc cctcgagctt tttatcaact
     3421 aaatcctgag caaacagaag tcctctatag cgaagcagta aaagcgctgg atgttgataa
     3481 agaaaaccat ttgattgacg cttattgtgg agttggaacg attggatttg cctttgcaaa
     3541 gaaagtaaaa acactcagag gtatggatat tattccagaa gctattgaag atgccaagcg
     3601 aaatgctaaa agaatgggat ttgacaatac tcattatgaa gctggaacgg cagaagagat
     3661 tattcctcgt tggtacaagg aaggctaccg agcagatgct ttgattgttg acccaccacg
     3721 tacaggtctg gatgataagt tattagatac tattcttact tatgtaccag aaaaaatggt
     3781 ttatatttct tgtaatgttt cgaccttggc tcgtgatttg gtacgcttag tagaagtcta
     3841 tgatcttcat tatatccagt cggtcgatat gttcccacat acagctcgaa ctgaagctgt
     3901 tgtaaaatta ataaaaaaag ttt
//
LOCUS       DAVLTT010000100         3873 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLTT010000100 DAVLTT010000000
VERSION     DAVLTT010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3873
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.100"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            285..1388
                     /gene="glf"
                     /locus_tag="VYN15_002020"
     CDS             285..1388
                     /gene="glf"
                     /locus_tag="VYN15_002020"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HEV1453278.1"
                     /translation="MYDYLIVGAGLFGAVFAHEAALKGKKVKVIEKRNHIAGNIYTRE
                     EEGIQVHQYGAHIFHTSDKEIWEYVNQFAEFNRYTNSPVANYKGEIYNLPFNMNTFNK
                     LWGVVTPAEAQVKIEEQRAILNGKTPENLEEQAISLVGTDIYEKLIKDYTEKQWGKPT
                     TELPAFIIRRLPVRLTYDNNYFNDTYQGIPIGGYTQIVEKMLDHENIDVETNVDFFVN
                     KEQYLKDFPKIVFTGMIDEFFDYKLGELEYRSLRFENETLDMENYQGNAVVNYTDAET
                     PYTRIIEHKHFEFGSQAKTIITKEHSKTWEKGDEPYYPVNNDRNNHLYKSYKKLADEQ
                     GNVIFGGRLGHYRYYDMHQVIGAALQCVRNELN"
     gene            1709..3691
                     /locus_tag="VYN15_002021"
     CDS             1709..3691
                     /locus_tag="VYN15_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1453279.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSAKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGETGASKILRNIFVPPTFVQAEGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
BASE COUNT         1314 a          621 c          783 g         1155 t
ORIGIN      
        1 tattagtaaa agttgtaagc gtagggattt ttctaactat tttctcactt gtattgaatg
       61 aaaatagcaa caaatggatt atttttcttt ctaatcaaac tatgggtatc tttataatac
      121 acacttatat tatgaaggta tgggaaaaac tatttggttt tagttttatg ggttcatatt
      181 tactttttgc tatatttact ttaagtgtta gttttatcat tgttggaatg ttaatgaaaa
      241 ttccgtattt taatcgaatc gtcaaattat aaaaaggaga aaaaatgtac gattatctta
      301 tcgttggtgc tggtctcttt ggtgcagtct ttgcccatga agcagcctta aaaggaaaaa
      361 aagtaaaagt tattgaaaaa cgaaatcata tcgcgggtaa tatctatact cgtgaagagg
      421 aaggaattca ggttcatcaa tatggtgctc atatcttcca tacttctgat aaggagatct
      481 gggagtatgt aaatcagttt gcagagttta accgttatac caattctcct gttgcaaact
      541 ataagggaga gatttataac ttacctttta atatgaatac cttcaataaa ctctggggag
      601 ttgtgacgcc agcagaagca caagttaaga ttgaggaaca acgtgctatt ttaaatggta
      661 aaactcctga aaatttggaa gaacaagcga tttctcttgt aggtacagac atctacgaaa
      721 aattaatcaa agactataca gagaaacagt ggggcaaacc aactactgaa cttccagcct
      781 ttattattcg ccgtttgcca gtacgtctga cctatgataa caactatttt aacgatacct
      841 atcaagggat tccaattggt ggatacactc aaatagttga aaaaatgttg gatcatgaaa
      901 atattgatgt agaaacaaat gttgatttct ttgtgaataa agagcaatat ctgaaagatt
      961 ttcctaagat tgtctttact ggtatgattg atgaattctt tgactataag ttgggcgaac
     1021 tagagtaccg tagtcttcgt tttgaaaatg agaccttgga tatggaaaat taccaaggaa
     1081 atgcagttgt gaactatacg gatgcagaaa ccccatatac tcgcattatt gaacacaaac
     1141 attttgagtt tgggagtcaa gcaaagacta tcattactaa agaacattct aaaacatggg
     1201 aaaaaggtga tgagccttat tatccagtta ataatgatcg taataatcat ttgtataaat
     1261 catataaaaa acttgctgat gagcaaggga atgttatctt tggtggccgc ttaggacact
     1321 atcgttatta cgatatgcac caagtaattg gagcagcttt gcagtgcgtg agaaatgagt
     1381 taaattaata ctcaatgaaa attaaagagc aaactaggaa gctagccgca ggttgctcaa
     1441 aacactgttt tgaggttgca gatggaagct gacgcggttt gaagagattt tcgaagagta
     1501 taaacaagta aaactgacta ccagttatta tttagaaata gtattaaaaa ttccttgact
     1561 atgtgatata gttgagggat ttttaaatga tattcatatt ttttgcaaag atgttgtttg
     1621 aaaaataatt ttcaaaaatt ctgaaaattc tgttgacaac tttctgaaaa gagtctataa
     1681 tggagagaaa gttttaaagg agaaaatgat gaaaagttca aaactatttg cccttgcggg
     1741 cgtgacatta ttggcggcga ctactttagc tgcatgctct ggatcaggtt caagcgctaa
     1801 aggtgagaag acattctcat acatttatga gacagaccct gataacctca actatttgac
     1861 aactgctaag gctgcgacag caaatattac cagtaacgtg gttgatggtt tgctagaaaa
     1921 tgatcgctac gggaactttg tgccgtctat ggctgaggat tggtctgtat ccaaggatgg
     1981 attgacttac acttatacta tccgtaagga tgcaaaatgg tatacttctg aaggtgaaga
     2041 atacgcggca gtcaaagctc aagactttgt aacaggacta aaatatgctg ctgataaaaa
     2101 atcagatgct ctttaccttg ttcaagaatc aatcaaaggg ttggatgcct atgtaaaagg
     2161 ggaaatcaaa gatttctcac aagtaggaat taaggctttg gatgatcaga cagttcagta
     2221 cactttgaac aaaccagaaa gcttctggaa ttctaagaca accatgggtg tgcttgcgcc
     2281 agttaatgaa gagtttttga actcaaaagg ggatgatttt gccaaagcga cggatccaag
     2341 tagtctcttg tataacggtc cttatttgtt gaaatccatt gtgacaaaat cctctgttga
     2401 atttgcgaaa aatccgaact actgggataa ggacaatgtg catgttgaca aagttaaatt
     2461 gtcattctgg gatggtcaag ataccagcaa acctgcagaa aactttaaag atggtagcct
     2521 tacagcagct cgtctctatc caacaagtgc aagtttcgca gagcttgaga agagtatgaa
     2581 ggacaatatt gtctatactc aacaagactc tattacgtat ctagttggta caaatattga
     2641 ccgtcagtcc tataaataca catctaagac cagcgacgaa caaaaggcat cgactaaaaa
     2701 ggctctctta aacaaggatt tccgtcaggc tattgccttt ggttttgatc gtacagccta
     2761 tgcctctcag ttgaatggag aaactggagc aagcaaaatc ttacgtaata tctttgttcc
     2821 accaacattt gttcaagcag aaggtaaaaa ctttggcgat atggtcaaag agaaattggt
     2881 tacttatggg gatgaatgga aggatgttaa tcttgcagat tctcaggatg gtctttacaa
     2941 tccagaaaaa gccaaggctg aatttgctaa agctaaatca gccttacaag cagaaggtgt
     3001 gactttccca attcatttgg atatgccagt tgaccagaca gcaactacaa aagttcagcg
     3061 cgtccaatct atgaaacaat ccttggaagc aactttagga gctgataatg tcattattga
     3121 tatccaacaa ctacaaaaag acgaagtaaa caatattaca tattttgctg aaaatgctgc
     3181 tggcgaagac tgggatttat cagataatgt cggttggggt ccagactttg ccgatccatc
     3241 aacctacctt gatatcatca aaccatctgt aggagaaagt actaaaacat atttagggtt
     3301 tgactcaggg gaagataatg tagctgctaa aaaagtaggt ctatatgact acgaaaaatt
     3361 ggttactgag gctggtgatg aggctacaga tgttgctaaa cgctatgata aatacgctgc
     3421 agcccaagct tggttgacag atagtgcttt gattattcca actacatctc gtacagggcg
     3481 tccaatcttg tctaagatgg taccatttac aataccattt gcattgtcag gaaataaagg
     3541 tacaagtgaa ccagtcttat ataaatactt ggaacttcaa gacaaggcag tcactgtaga
     3601 tgaataccaa aaagctcagg aaaaatggat gaaagaaaaa gaagagtcta ataaaaaggc
     3661 tcaagaagat ctcgcaaaac atgtgaaata actgttgcaa aatataagaa aggatttagt
     3721 atttctcttg aatgctgaat ccttttttac atttgtaaag aaagattcta aatgtactga
     3781 cccccaaaag ttggagcctc tttttgtcag aatagagaaa atttttgtta attttacttg
     3841 tttcctattg ctttctcagt tattatttgt tat
//
LOCUS       DAVLTT010000101         3813 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLTT010000101 DAVLTT010000000
VERSION     DAVLTT010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3813
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.101"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(<1..588)
                     /locus_tag="VYN15_002022"
     CDS             complement(<1..588)
                     /locus_tag="VYN15_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV1453280.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQ"
     gene            complement(888..3567)
                     /locus_tag="VYN15_002023"
                     /pseudo
     CDS             complement(888..3567)
                     /locus_tag="VYN15_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         1216 a          828 c          554 g         1215 t
ORIGIN      
        1 ttggttaaac tcagtacaat agaaatcttg aatgattttc tcaattccca taattatttc
       61 agtgatttta tacgactctt gaaaattatt ttctaaatta gcattaacaa aatgtagcgc
      121 tatgaatgca gcttcgtcaa ttggaagttc aatacctaac tcttttttta ttatttgtaa
      181 agcccttttc ccaagttcaa attcttcttt ataatatttc gatatttccc agcgtagggg
      241 attcgaaata ataatccctt ctttataacg ttctatgctc gaagaaatat gatccgttaa
      301 attaatatag ataatttcat caaaattatt acccaatgtt attttaccta ggttaattat
      361 tttttcggtg atgtacacca actccaaagg aacgttaata aacatctctg taaaacgggt
      421 catattatct ctatttttga gaaaaaaact tttctcaata tcaattggat ttactttatc
      481 tccagttttt cttccaaaag ctatgcccct tccaaaaaga agaatatcga tatctttttt
      541 actttgcgca attacggcat tgtggtttag tattcgtttt atgatcataa aatttccctt
      601 ttaaaataaa aggaacctac ttaaaaacat caagaaactt cttccgatgt gattaaatag
      661 gttcctgctc acttgtatta gtgataacat ccttttattt caatttttaa tggtgacatg
      721 aagcttaaat aattaataac tctgtaacca ttttcatttt atgatatttc aatctatttg
      781 tcaagtactt gtagaaattt ttttattttg tgtgattcga atgtgataat ggcaacagtc
      841 tcactaaaga aatgaaaatc atacatagaa atttttaaaa attttctcta tcgtaaacct
      901 gccactagtt cagaaactat actagctgat tccaaacgta atatggtcat ctcatctacc
      961 ttccctaata atggcattgc accataccaa acaatagtct tattcaccaa aagaataggc
     1021 gttactattt ttgattgagt aaaagacact ttaattttct ggctcttcaa ctggtctagc
     1081 catgctttat ttgcaaccgt ctctggtata catatctcaa tttgactaat cctaaattct
     1141 tttagaaaat tcatcagttt tgtctggtgc acataaggta aaataagcag acattcctgt
     1201 ctttcccctg ctaagtcctc tctcaacacc ttctcatatc tactatcaac ataaacgaat
     1261 tgtttctcct caccctcgat gacacgataa tccatctttc gataagctac ttgtcgtttc
     1321 tgaaacatct tttctaaata aggaacatga atatccacat aatcgaaaat acgcaccaaa
     1381 gacttatcct tgtagtttct atgaatccga cctgcatact gaattaaatt atttttccaa
     1441 gaaaagggtg ctgccaagat aagcgtgtcc aactgaggta agtcaaaacc ttcgccaatg
     1501 tattttccag tagacaacaa aacaaaccct ttatctaact gttctaacgt ctccagtaaa
     1561 ctcgttcttt ctcggacttt ggtttttccg ctaataatgt aacagtcatc aacctctttc
     1621 tctttcaata acttttcaaa gacatctatc tgttgaattc gattaactaa aaccaagata
     1681 ttccgtcctt ctgccacttg ggctagaata tccttgagaa tcaactgatt cctcgctgag
     1741 tctgtagcaa tccaatcact gagctgtata aaattacttg ctttggtctt ttcaatctcc
     1801 aaatgaccaa aagaagtgaa tcttaattgc aattgccgtt taaaatccgt ttccctctta
     1861 tcagcagtat ggagtatctc accaattctc tgaaaaacaa taggctcatg accattctta
     1921 cgctcaggcg tagccgtcaa accgtaaaga tacttccctc taaactgagc aacaactttt
     1981 tcaaacatca aggcagagac atgatgacac tcatccacaa tcatcatctc atactcatcc
     2041 aaaagacttt gactattttc caacttaaat agagattgaa tcataacgac atcaaccagt
     2101 ttactcagcc atttcttagt cccaccgtac tgtccaacat agccgattac cttttcacga
     2161 cctgatgccg tataacggat agcctcctcc tcttcgaaag tcaaaaagca gtttaagcga
     2221 tctagccatt ggtctaagag ttgcttatta tggactagaa taattgtttt tgttttccgt
     2281 tcagagataa gagcagcacc taaaacggtc ttcccaaaac cagtctccgc atgaagtaaa
     2341 ccattttctt tagaagtcat atctgacagg gctaactctt gctcaaaagt gagttctccc
     2401 ttaaattcca cgctaataga cctttgtacc tttctcctat cttccacaga tacctgctta
     2461 aatttatctt gcaatggata cagcaaacct cttggcaacc ataaataatg atcggattct
     2521 ccaaataaat acattctctc aggaatttga taggttggct gtcgcatagc ctgctttaaa
     2581 taaaattcgg gattagaaaa tgaagccata tttttcaaga aaaacagtgt cttgggtgtc
     2641 acagacgatt tttcaagttg gatcatattg gataagacga tcttcaactc cttgtccaat
     2701 tcttgcttgc ctaactcttc ttggattaac agtgccactt tagcagttga aaccctctga
     2761 atttcttgta gatacctcca ttggtcttca taaggctgaa actgttcatc cacaaagacc
     2821 gttcgccctt gatggtaagc ttctccttga aaaggcaagg caatcaaatt tccaaatccc
     2881 ccccttagga aggacatcct gatttagaaa catgcgatca aaagaatcaa aggacagttg
     2941 catactttcc tgcattgcca attctaatag tttctttcca aacaagcgag cctctcgact
     3001 cggaatagct tcctcaaaga agaaccaaat atggagtccg tgacccgaac gagaaatctc
     3061 tagatgggct tccatctggc gttccctggc tattcttcga atagttaaac cagcttcttt
     3121 ccaatctcct tcatcaaaat ccagtaccaa aaaataacag ctatcatcta agtgcatagg
     3181 aaagataccg atagctgtct ccccacgaaa atgagatttc aagacggagt ccgtcaatgt
     3241 ctggaaactc cgtttttcag gtggcaactg cttccaacca taatcatagg atggaaagta
     3301 ctgaattttc ccttgatcat tgataaaact cttagcataa acatcataac ggccagcaaa
     3361 cacggaggta aacaattgta atttttcttg cgtcgtcaag tgactacttt gaagttggaa
     3421 catctcctcg aaccaagagc gttccatcac aaactgactc ttgtctttaa gacgtttaca
     3481 caagaaaaac tcactatccc catcaaaaga agaaaagaca tcaagtactt ctaccacaat
     3541 tccatccaaa gacacaaaaa cagccataaa agtcgcctcc ttgattccta taggctgatt
     3601 ataacaagaa tagctgaaat tgtacacgaa aataaaatcc taatagtact cattttgtat
     3661 gtggctaata ttccgtctcg ctccggaatg tacgaggtaa atagagttta aacgagcagt
     3721 ctataaaatt caaaaaacgc atcatatcag gtgtacatga actacacccc aaaagttaga
     3781 cagaaaaaat ctaacttttg gggtgttttt att
//
LOCUS       DAVLTT010000102         3280 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLTT010000102 DAVLTT010000000
VERSION     DAVLTT010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3280
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.102"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            28..1308
                     /locus_tag="VYN15_002024"
     CDS             28..1308
                     /locus_tag="VYN15_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1453281.1"
                     /translation="MRIKSIYWNFGQNKPEKSFRYIDTSSIDRKKNIINYKNLQYLSP
                     EQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLIASTAFIVLDTLLNETYLKY
                     YLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLSEQQRIVEAIESALEKVDEY
                     AESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEE
                     GKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPI
                     YPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYH
                     ENKNPYVWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLT
                     KTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            1365..2162
                     /gene="psrA"
                     /locus_tag="VYN15_002025"
     CDS             1365..2162
                     /gene="psrA"
                     /locus_tag="VYN15_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV1453282.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            2173..2781
                     /locus_tag="VYN15_002026"
     CDS             2173..2781
                     /locus_tag="VYN15_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1453283.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETTSYPIYEIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIIFKVDLLFQKVSQLFE"
     gene            complement(2735..>3280)
                     /locus_tag="VYN15_002027"
     CDS             complement(2735..>3280)
                     /locus_tag="VYN15_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1453284.1"
                     /translation="IPMNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKP
                     LEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVATSLEHIGKFARIDKDYDGVVAGGF
                     IFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAP
                     FEEQELITQKVEKLFEKVNQL"
BASE COUNT         1184 a          486 c          539 g         1071 t
ORIGIN      
        1 tatgatattc ctgatacttg ggagtgggtg aggataaaat caatttattg gaattttggg
       61 caaaataagc cagagaaatc ctttaggtat atagatacgt ctagtattga tagaaaaaag
      121 aacataatca actacaaaaa tctacaatat ctttcacctg aacaagcgcc ttcccgtgct
      181 agaaaattag tttcgcagaa tagtgtctta ttttcaacag ttagaccata tctaaaaaat
      241 attgctgtag ttagagaact taaagagtat ttgatagcta gtacagcatt tattgttttg
      301 gatactttac ttaacgaaac atatttgaaa tattatttat tatcagataa ttttatcaat
      361 cgtgttaata ataaatctac tggaacaagt tatcctgcaa tcaatgatta taattttaat
      421 ctattattaa ttgctctccc cccactatcc gaacaacaac gaatagtaga agcaatcgaa
      481 tcagctttag aaaaagtaga tgaatatgct gaaagttata atagactaga acagctagat
      541 aaagaatttc cagataaact aaaaaaatct attcttcaat atgctatgca aggaaaatta
      601 gttgaacaag acccaaatga tgaatcagtc gaagttttac ttgaaaaaat acgagcagaa
      661 aaacaaaaac tctttgaaga aggcaagatt aaaaagaaag atttggacat ttctattgtt
      721 tcccaaggag atgataactc ttattatgag gaagtacctt gtgaaatacc agaaagttgg
      781 gaatgggtga ggttaaacga tataacctcc tacattcaaa gagggaagtc tccaaaatat
      841 tcaaatattc ctatataccc tgtgattgct cagaaatgta atcaatggtc tggcttttct
      901 attgacttag caagatttat tgatcccgaa acagttcata gttaccagaa agaaagatta
      961 ctaagagatg gtgatttaat gtggaattca acaggtctag gtacgttagg acgattagct
     1021 atttaccatg aaaataaaaa tccttatgtc tgggctgttg cagatagcca tgttacagtt
     1081 ataagagtct tatcgggagt tattaattgc catttcatct ataattttct ttcctctcct
     1141 attgttcagt cagttattga agaaaaagcg tcgggtagta caaaacaaaa agaattatta
     1201 acgaaaacta taaaagaata tttaatcccc ctcccacccc ttcctgaaca atccagaatc
     1261 gttgataaaa tcgaacaatt tttcgcccat attgacgcac taatttagta taatagtttt
     1321 acgtgcggtg gaatttctat caaacataag ataggagttt tacgttgaaa gattttgaat
     1381 tacatttgaa gaaagctggt ttagctgaaa atactgtgcg ttcgtacctt tatggtgttc
     1441 gatttttctt ggagaattac gaactcaaaa tggaagattt atttgaatac aaaggatatt
     1501 tattagacaa ttttaaacct aaaactgtca atttgcgact acaaggagta aataaatatc
     1561 tggcttttat tggtcatgat gatttgaaat taaaatttgt caaagtacag caaaaaccgt
     1621 ttttagaaga tgtcattagc catgctgatt acctttttct taaacgtagt ttgaaaaaag
     1681 atggtatttt aaaatggcat tttgtcgttt ggtttttagg tgcaactggg gctcgtgtaa
     1741 gtgaacttat taaactaaaa gtagagcatg tagaaatcgg ttattttgac atttactcaa
     1801 aaggtggtaa aattcgtaga ctgtacattc ctaaaaaatt aagaaatagt tgtcttagtt
     1861 ggttagaatc agaaaatcgc cgaagtggtt atttattttt gaataaattt aacgaaccaa
     1921 ttacagcaag aggagttgct caacagttaa aaaattatgc tgataaatac aaaatgaatc
     1981 ctaaagtaat ttaccctcat tcttttaggc atttatttgc taagaatttt ttagcgaagt
     2041 ataatgatat tgccttgctt gcagatttga tgggacacga aagtatagaa actactcgaa
     2101 tttatctaag gaaaacagct actgaacaac aaaatattgt agataaaatt gttaattggt
     2161 aaaaaataac aggtggtcaa actgactacc tgctattttt gtgattatgg ctcttattat
     2221 gggaacaaag acgaaacaac ctcttatcct atatatgaaa tcccagaagc atggagatat
     2281 attaaatttg ctagcctagt taacttcaga ataggaaaaa ctcctccacg cagtgaagct
     2341 actttttggg gaactgaaat accttgggta tctatatcag atatgcctat atctggttat
     2401 gtaactaata cgagagaatc tatttctaaa ttagcattaa aatcaaagaa aatagacatt
     2461 tcacctaaag gaactttatt aatgagtttt aaattatcta ttggaaaagt tgccatattg
     2521 gatattcctg ccactcataa tgaagccatt atatcgatat tcccctatgc taataaagaa
     2581 aatattatca gagattactt aatgatattt ttgccactta tctctacttt aggtgattca
     2641 aaagatgcta tcaaagggaa aacattaaat agtaccagta tctccgaatt attaatccct
     2701 atttctaatc atgaagagat gaaaagaatc attttcaaag ttgatttact ttttcaaaaa
     2761 gtttctcaac tttttgagta ataagttcct gttcctcaaa aggagctaac ggaattaata
     2821 gctcgctcag tgtagtttta ggaatattat ataaagcttg acctgatagt ttagttattg
     2881 ctttcaattg tttataaaat aacggagagg acaagttaaa taatagaaat tttgaaataa
     2941 tctctgaact ttcgaatggt gttaattgga aaataaatcc accagccaca acaccatcat
     3001 agtctttatc gattcttgca aactttccaa tatgttctaa agaggttgct acaggtgtta
     3061 ttagctgatt atgttttaaa taaacttgct cagaggagat gaattgtgta tcaatgtagt
     3121 aatcattatc caacagagaa aattctaaag gcttaatatt accaccacgt ataattctaa
     3181 cacctttatt attaatgctt aaatcgccct tcttgtaaga aagacctgta ttcattgaaa
     3241 aaatatcttt tatttttata acaacccaat tcataggtat
//
LOCUS       DAVLTT010000103         3243 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLTT010000103 DAVLTT010000000
VERSION     DAVLTT010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3243
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.103"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(162..416)
                     /locus_tag="VYN15_002028"
     CDS             complement(162..416)
                     /locus_tag="VYN15_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV1453285.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(436..2277)
                     /gene="typA"
                     /locus_tag="VYN15_002029"
     CDS             complement(436..2277)
                     /gene="typA"
                     /locus_tag="VYN15_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV1453286.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            2439..3164
                     /locus_tag="VYN15_002030"
     CDS             2439..3164
                     /locus_tag="VYN15_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HEV1453287.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDSCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYYVDKTYQVEVNGLLTPDHIQAFQKRIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
BASE COUNT          964 a          714 c          615 g          950 t
ORIGIN      
        1 atatgcaacc agtactaacc aaatataaaa tagatgccat taaagaattt tattcaagtt
       61 tttcccattc atattatcca aacaaaagag atggtgataa ctcaaaaata aattgcaatc
      121 ttgtaaaatt cctagcaaaa agagagccga aactctcttt tttatcttct tttacttttt
      181 ttaactggca tgagtgtgat gtctctaaca ctaaagtaag ctagaatcaa catggctatt
      241 gctaggaata tttctgttgg taattgaaaa attttcagaa aagatagaac caataaaatc
      301 aagagtgcca ctaaaataca taccatagcg acgatattga cagtcccttt aatgctttct
      361 ggtgtcgcaa atacatagag taggagcagt aaaattccta ggactaaata gaccatcttt
      421 ctctctttct agctcttatt cagctgattt tttcttcttg ttagctttct cacgctctgc
      481 tttgttaagg atttgtttac gcaaacggat agactcaggc gttacttcca tgtactcatc
      541 gtcgttcaag aactcaagag actcttcaag tgtcaagata cgaggcgtct tgataacagc
      601 tgtttggtcc ttagtagctg aacgaacgtt ggtcatttgt tttgccttcg tgatgttaac
      661 tgtcaagtca ttttcacgag agttttcacc gatgatcatt ccttcataaa cctcagtacc
      721 tgggttgaca aagatcgtac cacgttcttc gatagacatg attgagtaag ttgtagcctt
      781 accagcatcg atagaaacaa gggcaccacg gtgacgtcca ccaatttccc ctggaatcaa
      841 tggcaagtat tggtcgaagg tatggttcat gataccgtaa ccacgagtca ttgacaagaa
      901 ctcagttgag tatccaatca aaccacgcgc tggaacaagg aagaccaaac gagtttgacc
      961 attaccagtt gaaatcatat ccaacatttc acctttacgt tcagaaaggc tttggataac
     1021 agacccttgg tattcttctg gagtgtcgat ttgtacacgt tcaaatggtt cacatttaac
     1081 accgtcgatt tcttttacga taacttctgg acgagatact tgaagttcat agccctcacg
     1141 acgcattgtt tcgataagga ttgacaagtg caattctcca cgtcctgaaa cagtccattt
     1201 atctggtgaa tcagttgggt caacacgaag ggaaacgtct gtttgcaatt ctgcctgcaa
     1261 gcgttcttcc accttacgag aagttaccca tttaccttct ttaccagcaa atggtgagtt
     1321 gttgaccaag aaagtcattt gaagagttgg ctcatcgatg tgtaggattg gaagagcttc
     1381 tactgcatct gtcggagtga tggtttcacc gacaaagatg tcttccatac ctgaaacggc
     1441 aatcaagtca cccgctttgg cttcttggat ttcacgacgt tccaaaccaa agaaaccgaa
     1501 gagttttgta acacggaagt ttttagttgt accgtcaagt ttagaaaggg taacttggtc
     1561 cccaacctta actgtaccac ggaagacacg accgataccg atacgtccaa cgaagtcatt
     1621 gtagtccaaa agtgacactt ggaactgcaa aggctcatct gagttatcta ctggagctgg
     1681 gatatggtcg ataatcgtgt caaagattgg tgccatagtc gcttcttggt cagctggatc
     1741 atctgacaat gaagaagttc cgttgatcgc tgaagcataa accactggga aatcaagctg
     1801 gtcgtcatct gcaccaagct cgatgaaaag ttccaagact tcatccacta cttctgctgg
     1861 acgagctgat ggcttatcga ttttgttaac aaccacgatt gggacaaggt cttgttccaa
     1921 ggcttttttc aatacgaaac gagtttgtgg catggttcct tcataggcat ctacgaccaa
     1981 gacaacaccg tcaaccattt tcatgatacg ctcaacttct ccaccgaagt ccgcatgtcc
     2041 tggtgtgtcc ataatgttga tacgagttcc gttgtaagca acggcagtat ttttagcaag
     2101 gatggtaatc ccacgctctt tttcgatatc gtttgagtcc atagcacgct ctgccaattc
     2161 agtacgtgca tcaagcgttt ctgattgttt caataattcg tcaaccaggg ttgttttacc
     2221 gtggtcaacg tgggcgataa tcgcaatgtt acggatatct tctcttaatt ttgtcatgat
     2281 ttcctctata atattcaaaa tttattttct aactgaacga ttataccata atttcaaata
     2341 aataacataa ctcaagcaag tgtaaatgtt ttcactccgc ttttcttttc acgtcaagcc
     2401 ttttcaaagc aagcgactta tgataagata ggcacagtat gcgtttagat aatttattag
     2461 ctcaagaaaa aatcagccga aaggccatga aacaagcctt actcaaaggg gacattctcg
     2521 tcgatagttg cccagcccga tccctagccc aaaatatcga tacaggacta caagaactcc
     2581 tttttcagga tcgaatcatt caaggctatg aacacaccta tcttatgctt cataaacctg
     2641 ctggtgtcgt tacagccaac aaagacaagg aacttccgac cgtcatggac ctgcttccat
     2701 ctgacatcca gtctgacaag ctctatgccg tcggccgact ggaccgagat acaacaggac
     2761 tccttctctt gaccgataac ggtcccttgg gcttccaact cctccatccc caatattatg
     2821 tcgataagac ttatcaagtt gaggttaatg gacttctaac acctgaccat atccaagcct
     2881 ttcaaaagag aattgtcttt ttagatggta ctgtctgtaa acccgcaaaa ctagagattc
     2941 tatctgcaag tccctccctc agtcaagcct ctatcaccat ttcagaagga aaatttcatc
     3001 aaatcaagaa aatgttcctc tcggttggtg ttaaggtgac tagcctcaag agaatccaat
     3061 ttggggactt cacattgaac ccagatttag cagaaggtaa ctaccgccct ttgaaccaaa
     3121 aagagttaca aatcattaaa aactatttag agatgagtcg ataaaacaaa aaaagcttta
     3181 aaactaggct ctataatatt tgtagtgggt aaatccacta tagatattat ggagcctatt
     3241 tta
//
LOCUS       DAVLTT010000104         3082 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLTT010000104 DAVLTT010000000
VERSION     DAVLTT010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3082
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.104"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(128..1000)
                     /locus_tag="VYN15_002031"
     CDS             complement(128..1000)
                     /locus_tag="VYN15_002031"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV1453288.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFKRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALDDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            1237..2547
                     /locus_tag="VYN15_002032"
     CDS             1237..2547
                     /locus_tag="VYN15_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV1453289.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGKTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPTLFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            complement(2913..>3082)
                     /locus_tag="VYN15_002033"
     CDS             complement(2913..>3082)
                     /locus_tag="VYN15_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1453290.1"
                     /translation="TVSFAISSKGEKMKVENISYRVDHRILFDNISFDTLSSGVTLIT
                     GKNGTGKSTLL"
BASE COUNT          923 a          702 c          509 g          948 t
ORIGIN      
        1 aagattatac cacattgtgt actatttttg gttcatttta ctatatttga agaggcgttt
       61 aaactatctg acataaaact cgttctagag gaaagacatc ctttaaaaag ttagtttatt
      121 ttacaactta gacatcaagg taggttaacc ccttcatgga aaaatcaaga ctcttagcac
      181 tatgggttaa actaccactg gagacgtaat caatcgctaa accacgaaaa cggctaatag
      241 tggtcatatc aatatttcca gaacattcaa tccgagaacg tcctgcaatt agggtaatgg
      301 cctgttcaat ctgttccaat gacatattat ccaacatgat aatatcagca cccgccgccg
      361 cagcttcttc ggcagcagca aggctttcca cttccacctc gaccattttc acaaaaggag
      421 cataggcacg cgcttgagca attgcctttt gaacactacc tactgccgca atgtgattgt
      481 cttttagcat gatagcatct gataaattaa agcgatgatt atagccaccg ccaactctca
      541 cggcatattt ctcaaaaaga cgtaaattag gagtagtttt tcgagtatca aataccttaa
      601 tgcaatcatc gtctaaggct tctacataag cagctgtcat cgaagcaatc cctgataaat
      661 gttgtaaaaa attcaaggca acgcgttcac atgttaagag acttctcacc gagcctatga
      721 tttctaaaac caaatcgcca ctagtcaaac gatccccatc cttaaattga tgaggattct
      781 ggaaggtcac ctcggcatca aatagggtaa aaaccctttt aaaaacggtt agccccgcta
      841 aaacaccagc ttccttggca aaaagcgaca ccttggcttg gccatgatga tcaaaaatgg
      901 cattggtact gtaatcttcg gaatgaacat cttctcgcaa ggctgctttc aatgtatcat
      961 ctatttgaaa aggggttaaa tcagttgaaa tgattgacat cactaagtcc tctattttta
     1021 atatcacttg taagcattag aggcaatcac tattaacttc cataggaaat cacaagcctg
     1081 aatacctcat ttttaattct aacaagtgtc aatacaattg tcaagacaat tgtatttttt
     1141 ttgtgtataa tagtcaagta ccaataggaa acaggtggtc ttttgagcgc caaaattgcc
     1201 aacctatttc catattctaa ctgaaaggac aattcaatga ttcatttaat aatgattagc
     1261 gccattgctc tagccattgg aattggttac cgcaccaaaa tcaatattgg cctgctggct
     1321 attgcttttt cttacctcat cgcaaccact ctcatgggat taagccccaa agaacttctt
     1381 catttttggc caacctcact cttttttacc atttttagcg tctctctctt ttataacttt
     1441 gcaataacta acggtactct tgatgttttg gctcaacaca ttctctaccg cacacgcacc
     1501 taccctaacg ccctctacat gattttatac ctgatggcaa cccttttgtc tgctttaggt
     1561 gctggatttt tcactactat ggccgtttgc tgtcctctag cgattaccct ctgtcaaaaa
     1621 gcggacaaac accctttgat tggagctcaa gccgtcaatt ggggagcttc aggaggggct
     1681 aatttgataa ccagtagctc aggcattgtc tttcaaggcc tgtttaagca aatgggatgg
     1741 gaagagcaag ctttttcact tggcaatcat atctttatcg tcagcattat ctacccactc
     1801 atcgtcttgc ttttattatc ctgttacagt cactatagta agggaaaaac aaactcatcc
     1861 ttgactattg accaaccacc actcctcagc aaggttcaaa gacaaaccac cttgctcatg
     1921 atcagcagca tggttttggt ttggcttttt cccttgttgc atctcatttt cccaaacatc
     1981 gcctggatag ctacttatca aaaaacattt gatattggct ttgtctcaat actcatggtc
     2041 tgcctcgcct taaggctcaa attagggaag caagaagcca ttttagctaa ggttccctgg
     2101 gctacaatta tcatgctctg cggcatgagc ttactaatgt ctctagcggt caagtcaggt
     2161 ttagtcacac tgatagggca cctcatgaca acaaccattc ctcatttctg gttacctctg
     2221 ttcttttgtg tgatagccgg agtgatgtca ctctttagtt ccaccctatc cgttgtagct
     2281 ccaaccctct ttcccatcat tgctatcatc agtgctcaaa atcctcagat tgatattcac
     2341 ttactcacaa cagccaccgt tattggcgct ctatctacta atatctcacc cttttcatca
     2401 gctggttctc tcattcaact ctcacttccc aatatagagg aacgtggcct tgccttcaaa
     2461 aagcaaatta ttctgggtgt ccccatcagc ttaagtttgg gactcttgac cacctggatt
     2521 ctcatccttc tagcttcctt aagttagatt tattatctaa cttaagggtg gacttggtat
     2581 aataaagtag acacaaaatt aagtggaaac gaggaaaagt cattatgcca aaaaaaacct
     2641 ttgataaagc cttcaaactc tctgctgtaa acctcatcct gtaaaaatga ttagttcaac
     2701 tttaaaaatt catcccaata gtctttatcg atggattcaa gaatatgaaa aatatgaaga
     2761 aagtgcgttc ccaggacatg ggagcgcact tcgtcatact caatttgaaa tatagtgaaa
     2821 tgaaataaga ccaggacaaa tagatcagga tagtcaaatc gatttctaac aatattttag
     2881 aagtagatgt gtactattct agtttcaatc tactatagta aagttgactt tcctgtacca
     2941 tttttaccag taattaatgt cacgcctgaa ctcaaagtat caaaagaaat attatcaaac
     3001 aatatacgat gatccaccct atacgaaata ttttctactt tcattttttc tccttttgaa
     3061 ctaatagcaa aagaaacagt tc
//
LOCUS       DAVLTT010000105         3070 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLTT010000105 DAVLTT010000000
VERSION     DAVLTT010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3070
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.105"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(65..262)
                     /locus_tag="VYN15_002034"
     CDS             complement(65..262)
                     /locus_tag="VYN15_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1453291.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(337..1113)
                     /locus_tag="VYN15_002035"
     CDS             complement(337..1113)
                     /locus_tag="VYN15_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV1453292.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            1235..1981
                     /locus_tag="VYN15_002036"
     CDS             1235..1981
                     /locus_tag="VYN15_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1453293.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            1994..2974
                     /locus_tag="VYN15_002037"
     CDS             1994..2974
                     /locus_tag="VYN15_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV1453294.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
BASE COUNT         1086 a          376 c          572 g         1036 t
ORIGIN      
        1 gatgttcaca tcttatttca attcactata ttagagtaaa attctctaca aaaagaagaa
       61 cagcctattt gactattctt ccgagtgatt tcaatttctt tggggaaata tggagatact
      121 ttttaaatac tttggcaaaa tatttatagt ctgaaaatcc aacttggtca gagatagcgc
      181 ttaaagggga gttgggagat tcagccatct tatctatagc ttgtttcagg cgatattgta
      241 agatatattc atttagagtc atggggaagt cttctttgat aaccttatat agatgcttgt
      301 tatctgcaaa tagctagagc atttcaagga aatgaactag aaataacaat taatatggtg
      361 gttcagaaat accttttgat aatcaataag atcttcagga tgaagtgcgt tgactccatc
      421 catttcatat ttccgattta ataaacgata tttgttttca ccaaattgat gaaaagggag
      481 tagttgaact tggtcgatat ttaatgagtt aaatagagta gcgaattttt ctgcatcctc
      541 taaactattg ttaaaattag gaataactgg gattcttaaa acgatagttt tattttgaga
      601 aaaagcataa tgaatgtttt taataatcat ttgattaaaa accccagtca cttttttatg
      661 ttttatagaa ttataatgtt ttaggtctgt gtagataaaa tccacatatt gaattaaatc
      721 gataaatttt tcatgatcaa caaaggcagt agtttcaatg gcagtgtgta tgtgatgttc
      781 tttagctgat tttaagatgg ctttagcaaa ttcaaactga gcaaatattt cacctcctga
      841 taaagttaaa cctccaccgg attcttcgta aaattctttg tcttttaata cctctgtaat
      901 aatttcttct acagtctttt cttcaccgac taaggtgaat ttctctcgtt gagcatcttt
      961 cattttttca ggtttcattc tttgagattc aggattagaa caccatggac agcgcagagg
     1021 acatcctttt aaaaaaacag ttgtacgaat acccgggccg tcatgaattg aaaagtgttg
     1081 aatattaaaa ataattcctt tagatatttc cataagagtt cctcctcttc ataagtctat
     1141 cctatcacaa aaacgaaaga aaaacaatta cgaacgaaag tttaatttgt tgttttttgt
     1201 tttttatttt ggtagaataa aacggaggtg taaaatgaaa agattggaac aaattattaa
     1261 attagtatca gaatatgaaa agatcgacgt taatacatta tcggaaaaat taaatgtatc
     1321 gaaagtaacg attagaaaag atttagataa attagagtca aaaggtttat tacacagaga
     1381 gcatggatat gctgtattaa atagtggaga tgacttaaat gtacgtttgt caattaatta
     1441 tgaaattaag agaaaaattg ttcaggaagc agtaaaattg gtgtcagata atgaaacaat
     1501 aatgatagaa tctggatcga cctgtgcttt acttgctgag gaaatttgca agcaaaaaag
     1561 aaatgttacg attgtaacaa attcattttt tatagcaaat tttgtgagag cttatgattc
     1621 atgtcgtatt attgttcttg gtggagagtt tcagaaggat tcacaggtta ctgtgggacc
     1681 tttattaaaa gaaatgatac agacttttca tgtgcatcaa gcttttgttg ggacagatgg
     1741 ttacgataaa gagatgggct ttacaggaaa agatttaatg cgcagtgagg tagttcaata
     1801 tatttcagca gcgtcggata aagtcattgt actaactgac tcaagtaaat ttgataaaag
     1861 gggtacagta agaagatttg ctttaagtca agtctatgaa gtaataacag acgaaaaact
     1921 ttctaaacaa aatatagcta cattagaaaa tgctgggata atggttaagg tagtttcgta
     1981 agaggttaag tgtatgaatc aagataggaa taaactgctc tctaaaattg cttatctgta
     2041 ttatattgaa aacttaaatc agtcacaaat agcagcaaaa ttaggaattt atagaacctc
     2101 tattagtaga atgttaacag aagcaaggaa tgcaggaatt gttaaaattg aaatagagaa
     2161 ttttgataca aatatgttta agttggaaaa ttatgtaaaa gaaaaatatg gtctggaaag
     2221 tttagaaatt attccaaatg aatttgatga taatccaaca attttatctg aaagaatttc
     2281 tcaagttgca gcaggtgtcc ttaggaattt aattgatgat aatatgaaaa ttggcttttc
     2341 ttgggggaaa agtttaagta atttagtaga tttaattcac agtaaaagtg tccgaaatgt
     2401 tcacttctat cctctagcag gtggtcctag tcacatacac gctaaatacc atgtgaatac
     2461 actgatttat gaaatgtcta gaaaatttca tggagagtgt acatttatga atgcaacgat
     2521 tgtgcaagaa aataaattgt tagcagatgg tattttgcaa tcaagatatt ttgaaaattt
     2581 gaaaaatagt tggaaagatt tagatatagc tgtagtcgga attggtgatt ttagcaataa
     2641 aggaaaacat caatggttag acatgcttac agaggatgac tttaaagaat tgaccaaagt
     2701 taaaactgta ggagaaattt gttgtcgatt ttttgattca aaaggtaaag aagtctatga
     2761 aaacttacag gaaagaacga tagcaatctc tttggaagat ttaaaaaata ttcctcaaag
     2821 tttagctgtt gcttacggtg atacgaaagt atcttcgatt ctttctgtct tgcgtgctaa
     2881 tttagtaaat catttgatta cagataaaaa tacaatttta aaagttttgg aagaagatgg
     2941 ggatttgact tttagagaga ttctaggtga gtgaaaatga tagactgatc agtttatcgt
     3001 tttttctttt tagtcgattg cacatttgtg ctcatataaa caaaaatagt ttatctgttg
     3061 tttttggatt
//
LOCUS       DAVLTT010000106         3063 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLTT010000106 DAVLTT010000000
VERSION     DAVLTT010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3063
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.106"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..274
                     /locus_tag="VYN15_002038"
     CDS             <1..274
                     /locus_tag="VYN15_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453295.1"
                     /translation="DNRVLALIFLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALD
                     VIAYLFLGYLLVIQKAGYLFSVLLLFSNFSVPFIKAKEYELFKNSK"
     gene            1407..1646
                     /locus_tag="VYN15_002039"
     CDS             1407..1646
                     /locus_tag="VYN15_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453296.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            1631..1909
                     /locus_tag="VYN15_002040"
     CDS             1631..1909
                     /locus_tag="VYN15_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453297.1"
                     /translation="MYNDVIERISLCEFIGDIFYSKITSCCIVAKDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            2196..>3063
                     /locus_tag="VYN15_002041"
     CDS             2196..>3063
                     /locus_tag="VYN15_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEV1453298.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTFVRAEDAPVANQSQAEK
                     DYDAAMKKSEAAKKEYEDAKKVLAEAEAAQKKYEDDQKKTEEKAEKAKAASEEIAKAT
                     EEVQKAVLDYITAIRNHNESGKKSAEEAEKKAKERETAARKKFDTIQTTIVVPEPDEL
                     AKTQKKAEEAAKNKPELTKKLEEAKVKLEEAEKKATEAKQKLDAEEVALQAKIAELEY
                     EVQRLEKELEEINESDSEDYAKEGFRAPLQSKLDAKKAKLLKLEELSGKIEELDAEIA
                     ELEVQLKDAEGNN"
BASE COUNT         1103 a          412 c          601 g          947 t
ORIGIN      
        1 tgataatcgt gtattggctc ttatcttttt gataaaaatt tgtgtagata ctacgataaa
       61 atttttattc atcagattat ttgacacaag tactttaatg aagaggagaa tattttttct
      121 tttcgcattg gatgttatag cttacttatt tttaggatat cttttagtga ttcaaaaagc
      181 aggctatttg ttttcggttt tacttctttt ttctaatttt tcagttccat ttatcaaagc
      241 aaaggaatac gaattattta aaaatagcaa gtaatagaaa cataggttaa atcttagaac
      301 ggcttaaaat cagatataat aaagggaaat agtcttatct aggtaactaa gtgctacaaa
      361 cacagtcgag gatcacttgt taggattaca ttttaatcat gcttaataag aatggagaat
      421 tcctatgggg attgtattac tctgaagttt cgaatacctt agttctcgtg attttgagct
      481 gttctagctt tagaatcctt cagaatgtaa aattttaagc agtcaaagac ttagaatagc
      541 ctggaaacat ttattttata gcaattctag gcttagaatt gctcatatat atgtatttga
      601 gctgctcgat agttaggaca gctctattct gagaaatctg agctatcaat gcttcagaat
      661 agtatttcgc aaatggtttt tattgaagag gtgattgttt tatgatagtc taaaataaaa
      721 ctgatttaat ggagtaaatg gagaatcgtc acatgaaaca tttttttgca ggaattggtg
      781 agataaaact tgttggctac ttattgtata tatgtgtagg actagcccct ctttttcata
      841 tatatgtcat aggttcggaa ctgagttttg tgaaaatagt gttatctatt ttgggagtta
      901 tatttgtaag tatgttaact attgctcgaa tttatcggac ttttctataa agaatagttt
      961 ggacttgaac tgtatctaaa aacagaggtt ggtcgattat cagcctcttt cttgtcgttg
     1021 aaaagagtga gatatattga cttttgaaaa aaatgtcata attgagttgg gataaaccta
     1081 aaagtaatat agtagattga atctggaata gtccgttatg actgttaaaa tatttctaga
     1141 aattaatttg actttcctaa tcgatttgtt cacatcttgt ttcaatctac tatactttct
     1201 cgttaaaccg ttcggcaatt catggtgaca tggacacata gtagtaagca cactatgtgg
     1261 cttggcagag ctaaaaactg ttcccttgcg ataagcctaa taagcacaac atagggagtt
     1321 agagaagccg actctaatca accactttgg gcagtagtga gaactgcccc gtgctttttt
     1381 attttgagaa aatatggagt ttgtcgttga aattacttga ttgtattttg gactatcaag
     1441 aaagattcaa tggaaaaaca tgtcaagtat caacgaatta taagtattta gagactttca
     1501 aagtgaattt ttgcttgact gatttacatc atttatttga cttatacaaa atcacacgag
     1561 attatgctag tcaaacaaaa cctgctattc aagctggtgt ttttatttta gaagatttta
     1621 gaaatatcct atgtacaatg atgtaatcga aaggatatct ttatgtgagt ttatcggcga
     1681 tattttctat tctaaaataa caagttgttg catcgtagct aaggatttat ctaaaaatac
     1741 tatgaaattg gacgtcatat tttttgagga taaaaataaa agatccgcag ttttaggttt
     1801 acgaagagac aaaagcggag tatttaaacc agttacccta cattttacaa gcgctaagaa
     1861 atatgctaaa gttcgtaaaa cagatgtgaa ggaaatgaaa tggctataaa gattgtccgc
     1921 aggcttaagc ttgcgttttt tgttgtttaa cgaaattaaa aaaacaagct ctctcatcgg
     1981 aaatgttttt ataggaatga aggaagatga tgctatgttt aaaaagagaa tcgaaaaggg
     2041 caaaagtagt gtctttatct ttttggagta gaagcttatg atatagaaat ttgtaataaa
     2101 aatgtaatat aaaacatttg acaaatattt acggggggag tatacttaat ataagtatag
     2161 tctaaaaatg actatcagaa aagaggtaaa tttagatgaa taagaaaaaa atgattttaa
     2221 caagtctagc cagcgtcgct atcttagggg ctggttttgt tgcgtctcag cctacttttg
     2281 taagagcaga agacgctccc gtagctaacc agtctcaagc tgagaaagac tacgatgcag
     2341 caatgaaaaa atctgaagct gctaagaaag aatacgaaga cgctaaaaaa gttttagctg
     2401 aagcagaagc tgctcagaaa aaatatgaag acgatcagaa gaaaactgaa gagaaagcag
     2461 agaaagcaaa agcagcttct gaagagatag ctaaggcaac agaggaagtt caaaaagcgg
     2521 tcctagatta tataactgct atcagaaatc acaacgaaag tgggaaaaaa tccgcagaag
     2581 aagctgagaa aaaagctaag gaacgcgaaa ctgctgcgag gaagaaattt gatactattc
     2641 aaacaacaat agtagttcct gaaccagatg agttagctaa aactcagaaa aaagcagaag
     2701 aggctgcaaa aaataaacca gaacttacta aaaaactaga agaagctaaa gtaaaattag
     2761 aagaagcgga gaaaaaagct actgaagcca aacaaaaatt ggatgctgaa gaagttgctc
     2821 ttcaagctaa aatcgctgag ttggaatatg aagttcagag actagaaaaa gagctcgaag
     2881 agattaatga gtctgattca gaagattatg ctaaagaagg tttccgtgct cctcttcaat
     2941 ctaaattgga tgccaaaaaa gctaaactat tgaaacttga agagttgagt ggtaagattg
     3001 aagagttaga cgctgaaatt gcagaacttg aagttcaact taaagatgct gaaggaaaca
     3061 ata
//
LOCUS       DAVLTT010000107         2951 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLTT010000107 DAVLTT010000000
VERSION     DAVLTT010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2951
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.107"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(105..2363)
                     /locus_tag="VYN15_002042"
     CDS             complement(105..2363)
                     /locus_tag="VYN15_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1453299.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPSISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2592..2822)
                     /locus_tag="VYN15_002043"
     CDS             complement(2592..2822)
                     /locus_tag="VYN15_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV1453300.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
BASE COUNT          802 a          604 c          606 g          939 t
ORIGIN      
        1 attatatatc ataatggaca aagggcaagc tgtcaagaaa ttacagttat tttagtaaaa
       61 aaagaagcag aaaaatttca ttttctactc cttttctata ggatttattt ttctttttca
      121 gaacttttaa cttcagcttt tttggcagat ttaatctgaa tgtttccctt gctagtcata
      181 actgctttga gatctttttc gcttggattt tcaaggtagt agtcagtgat tgtgtcctca
      241 atatagtctt gaatagtccg acgaagtggg cgtgctccca tttttggatc ataacctagg
      301 tcaaccaact tttccttgac cttatcagtt acatccaaac gaatgttgtt gctagagagg
      361 cgcttgttaa catctgctag catgagctcg acaatctgaa ggaggttatc cttgctgaga
      421 gccttaaatt cgataatgcc atcaaaacgg ttcataaact ctgggctaaa gaagttaccg
      481 agttcaccga ggacagaatt ggtacgtcct tctctagcag caccaaatcc aacgctagct
      541 tcggtctttc ctgtacctgc atttgaggtc atgataatga tggcatcctt gaagctaacg
      601 gtgcgtcctt gcccgtctgt caaacgacca tcgtccaaga cttgaagaaa catgtgcata
      661 acatctgggt gagctttttc cacttcatcg agaaggatga gagaatatgg attgtggcga
      721 actttttcag ttaattgacc agcctcatca tagccaacat aacctggagg agcgccgacc
      781 aacttagcca cactatgttt ttccatgtat tcactcatat caaagcgaat catactatca
      841 gcagaaccaa aaagttcgat agccagttgt ttggaaagtt ctgtcttacc gacaccagtt
      901 ggcccaacga agaggaagct tccgattggg cggttagggg taccaagtcc gacacgatta
      961 cggcgaatag ccttggcaat cttatcgact gcatcatctt gaccaataac atgagacttg
     1021 agatcttcgg ctagatggat gagttgagat tgttctttct ctttcaaatc accaacaggg
     1081 atattggttt tctgctcgat aatgtgctca atagttttct cgctgatgct aggagtatcc
     1141 tggtctgtga tctttttctt ttgcatttcc ttatacttgg caatctggtc gcggaagtag
     1201 gccgccttct caaaatcttc ttctcgtgta gcttgagact tgagattttc agcctcaatc
     1261 aagcgctgat caattacttt aggatccaca aaattcaagg tcaagttcat cttagaacca
     1321 gcttcatcta ggaggtcaat ggccttgtca ggcaagaagc gatcttggat gtagcgattg
     1381 gaaagagttg cagctgcttc aatcgcagca tctgtatatt gaacgtggtg gtaatcttcg
     1441 tatttctttt gaatcccttt gagaatagtg attgtttcgt ccaccgttgg ttcatcgact
     1501 ttaacaggct gcatacgacg ctcgagggca gcatcctttt caatgatacg gtattcattg
     1561 agggtagtag caccgactag ttgcagttct ccacgagcaa gggctggctt gaggatattt
     1621 cctgcgtcca tattaccatc actcgcagaa ccagcaccaa caatttcatg gatttcatcg
     1681 ataaagagga tgatgtcttc acgtttgcga atttcttcca tgagtttttg catgcgttct
     1741 tcaaattgtc ctcgaatccc cgttccttga actaagctaa ccacatccag acggatgact
     1801 tgtttacctt ggagtttatg tggcacatcg ccatcgacaa ttttctgagc tagaccttcg
     1861 acaacggccg tttttccgac accaggttca ccgataagga caggattatt cttggttcta
     1921 cgattgagaa tctcgatgac acggataatc tcatcgtcgc gcccaataac ggggtcaatg
     1981 tctccacgac gggcaatttc agttacatta ataccaaatt cttccagcag gcctttttct
     2041 tggctaggtg gcggagtttg agcagatcca cgattttggg aaccataacc gccgtttcca
     2101 ccgtaacctc cacctgattg ggttggggga ataggaggag tattgctaga aggtctgaaa
     2161 ttgtttagat cattgaagaa atcaccaaag ggatcgaagt cacgattgtt cagatccgtc
     2221 atacctttga agaggctatt gttaggatct gttttgataa tcttatagca gttttgacag
     2281 aggtcaattt gtttttgttt tccattgaga ttggtgtaaa gatgaattgt tgagtcgtta
     2341 attttacagt tttgacaaag catacatcta cctcatttct ttctttagcc tgacttgttt
     2401 aaaggtcaaa aatagtcaaa ttctatactc tcattataac aggattgggg tgtaaagcaa
     2461 gtaaaaagat tgaagctttg agaagttgtt acaatgaaaa tttttgtgaa tttggactat
     2521 aaaaaaatcc tatttgtgag acaaaaagga ttttacttag acatgcaggg acaatcccag
     2581 cttgttttag attagtagag aagttcgtaa atttccattg cgattaagtc aatgctatca
     2641 aacgtatacg tttcgcgatc ttctacgtca cgaagggtaa agattgggcc gttttcttcg
     2701 tcgtggctgt acgcaacttc tgcaacaaca actccttcgc gttcaaaatt acgttttaaa
     2761 tttccgccat cgtttgccat tgcttcaagg cggttgatga ttctaaccaa atgtgattcc
     2821 attttgattc tccttcattt cttatcgtta ctattttacc ataaaggagg ccaacttgac
     2881 tagaaaaaac taagatttct cgctaattct gctagtttaa atatttttaa ataaattgga
     2941 taaaaaattt a
//
LOCUS       DAVLTT010000108         2881 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLTT010000108 DAVLTT010000000
VERSION     DAVLTT010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.108"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(73..534)
                     /locus_tag="VYN15_002044"
     CDS             complement(73..534)
                     /locus_tag="VYN15_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1453301.1"
                     /translation="MGKERREQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(501..644)
                     /locus_tag="VYN15_002045"
     CDS             complement(501..644)
                     /locus_tag="VYN15_002045"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEV1453302.1"
                     /translation="MAYSTDFKQGALDSIKGGHRHVEAAKVFDVGVRTLFTWEKKDVS
                     KGT"
     gene            914..1294
                     /locus_tag="VYN15_002046"
     CDS             914..1294
                     /locus_tag="VYN15_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1453303.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            1393..1614
                     /locus_tag="VYN15_002047"
     CDS             1393..1614
                     /locus_tag="VYN15_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1453304.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            1631..1945
                     /gene="trxA"
                     /locus_tag="VYN15_002048"
     CDS             1631..1945
                     /gene="trxA"
                     /locus_tag="VYN15_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1453305.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            2250..2783
                     /gene="queF"
                     /locus_tag="VYN15_002049"
     CDS             2250..2783
                     /gene="queF"
                     /locus_tag="VYN15_002049"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV1453306.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT          896 a          607 c          542 g          836 t
ORIGIN      
        1 taaagacacg caaatgagta taaatcagct aatttttggt ttgcattcct atttttatgc
       61 ataattattc tgtcattctc taatttgtga atcaatatat ctgattagaa aactaccatt
      121 gagtttttgc tccacctcat tagtccgctc aaaacgccgt ccgctaatct tgtcatagac
      181 tttctcccct ctaggagccc ctgcataagg acgatagagg tagcggttga ttcccgtttc
      241 gtcaatatat aggactggta aatcttttag gttatccaaa atatcaagaa actcagaaac
      301 tttctcaggc ttttgttccc taaaactggt cgtctttttt aaaatgacct taatctgctt
      361 taaaactgcc catacggagg gcaaagcaca atcaaaacgg gccgcaattt cccgtaaaaa
      421 agcgtctgga tgagcctcta caaaggcttt caattcttct aaagggatct tacgcttttt
      481 gacgactcgc tttttccgct ctaagttccc ttgctcacgt ctttcttttc ccacgtgaag
      541 agagttctga cgccgacatc aaaaactttg gccgcctcga catgtctgtg ccctcctttg
      601 atggaatcta atgctccttg tttaaaatca gtactatatg ccatagcttt attagaccat
      661 gcttatttta aactaagcaa ctatagatag agaaatgaaa taaaatctga attcgaatgt
      721 gataaggagt tagaaattga aacaatagga ttcccccatt attcacacaa aaataaaacc
      781 actaaaaaac agagcttgcc agcattcttg aaaagtagta taattattgc atgcgcaatc
      841 atcttgtgac gcagagactg cccgttaatg gactttcttc tataattatg actctaaaaa
      901 gaaaggagac actatgacct atttggaaaa atggtttgac ttcaatcggc gtcagaaaga
      961 aattgaaagt ctcttggaag agaccattgc ccaacagagc gagcaaagtc tgaccttgaa
     1021 agagttctac ctgctctact atctggactt ggctgaagaa aaatctctac gccagattga
     1081 cctgccagat aagcttcatc tgagcccgag cgcagtttct aggatggtgg ctcgcttgga
     1141 agctaaaaat tgcggtctac tcagtcgcat gtgttgccat caagatagac gctctagttt
     1201 tatctgcctg acaaatgatg ggcaaaagac actggcctcg ctacaaaaga ctgtcgaaga
     1261 aagcttggaa gcaggtttgg atttcttgat ttaagatgat tttaaaaaaa gttgcgtgcg
     1321 caatcatttt tcttgacatt ctcttttata aggagtaaaa taaagttagc attaaacaaa
     1381 ggagttttaa acatgattga aattacctat atagatgcca gcaagaacga aagaactgtg
     1441 actttcgagt cttatgaaga ctttgaacgt tcgcaacaag cttgccttat cggcgtcgca
     1501 gactactacc ctgtccaaaa attaacttac aagggtcata atttggacta ccatgggact
     1561 tatggagata tcttcttcta tctcatgaaa caagatttaa gccaatataa ctaaaaaaag
     1621 gagaaataca atggcaaaag caattacaga tgcaacattc gaacaagaaa caaaagacgg
     1681 tttggtctta gtagacttct gggcaacttg gtgtggtcca tgtcgtatgc aaggtccaat
     1741 cttggacaaa ttgtctgaag aactttcaga agatgtcttg aaaatcgtta aaatggacgt
     1801 tgatgaaaat ccaaacacag ctcgtgcttt tggaatcatg tctattccaa ctcttctctt
     1861 caaaaaagac ggccaagttg tcaaacaagt tgcaggtgtt cacacagcag aacaaatcaa
     1921 ggccatcatt gctgaattga gctaatcaaa cgagagacca agtactttct ttggtctctt
     1981 ttttcttgtc ctttgccatt tttcaaaaaa tatgctagac tatagttgat tgacactaga
     2041 atagtacacc tctacttcta aaacattgtt agaaatcgat ttgattgtcc caatcggttt
     2101 gtcctgttct tatttcattt tactatataa gtagaatatt acgatgtttg ggatatgtca
     2161 tcgctaaaaa aactcgattt ggtatttttt agctccctaa tgggagcttt ttgcgtgctc
     2221 tgaacatttc ccattttaga aggagtacta tgaaacgtca atcagccttg gtcgtcttta
     2281 gtggtggtca agattcaaca acctgccttt tctgggccat gcaacactat gaaacagtcg
     2341 aagctgtcac ctttgcctac ggccaacgtc atcacctcga aattcaaatt actagagaaa
     2401 tcgctaagga acagggcatt cgtcaccata tcctcgatat gtctctgctg ggacaaatca
     2461 ctgctcagcc agactttgcg acgattcata tttcctacat tcctgacaag ctctgtgtcg
     2521 agtcaaaatc cctcaaacta tatctattta gctaccgaaa ccacggagat ttccacgaaa
     2581 actgtatcaa caccatcggg aaagacttgg tcaacttgct agaccctcgc tatttagaag
     2641 tctggggaaa attcactccg cgcggtggca tttcaatcga cccctactat aactacggta
     2701 agcaaggaac taagtatgag ggcttggcag aacaacgcct cttccaacac gacctttatc
     2761 cagagaaaat tgacaaccgc taaagtcata ctcaatgaaa atcaaagagc aaactaggaa
     2821 gttagccgca ggttgctcaa agcagtgttt gaggttatag ataagactga cgaagtcagc
     2881 t
//
LOCUS       DAVLTT010000109         2746 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVLTT010000109 DAVLTT010000000
VERSION     DAVLTT010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2746
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.109"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(<1..328)
                     /locus_tag="VYN15_002050"
     CDS             complement(<1..328)
                     /locus_tag="VYN15_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453307.1"
                     /translation="MSEVDFNEAVTYEFTSDTCQLANSIYQSLFKFFDKKNFSDDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNCNGCMGDFPHDFF
                     DIYLDHV"
     gene            complement(386..1099)
                     /locus_tag="VYN15_002051"
     CDS             complement(386..1099)
                     /locus_tag="VYN15_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV1453308.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            1661..>2746
                     /locus_tag="VYN15_002052"
     CDS             1661..>2746
                     /locus_tag="VYN15_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEV1453309.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADVYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDENLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCI"
BASE COUNT          856 a          565 c          471 g          854 t
ORIGIN      
        1 ctacatgatc taggtatata tcaaaaaagt catgaggaaa atctcccata cagccattac
       61 aattcatatt gaggctatat tttcgattag taagataatt cggaaatata tttcctatta
      121 ctctaagatt atctacttgt gaatcccttc tcccaatata atccccttct ttgactaatg
      181 atggagattt ccaagtaaaa attaaatcgt cagagaaatt tttcttatca aaaaacttaa
      241 aaagagattg ataaatacta tttgctaatt gacaagtgtc agatgtaaat tcataagtaa
      301 cagcttcatt aaaatcaact tcagacattt caatgtactc ttcaatagta atattagctt
      361 ttttgtagtc attagctcgt ctcctttaaa atgtgatctt ttcaagaata tttttatcta
      421 aacaatccag caagtcttgg taagaataga cttcgtaagt cggctgggct tgtgtgtgat
      481 tttcgaggtg atgaggatta taccagatag tgtcaatccc cgcattattg ccaccttgaa
      541 tgtcggcagt tagagaatct ccaatcatca gcgtcttttc tttactaaat ccagcaattt
      601 gctggccaat cttttcataa aagagagcat ccggcttttg agtttgcaac tgttctgaga
      661 taaagacttg attgaaataa ggtgctagac cagattgagc caaacgtcct gtctgaatgg
      721 cagtaatgcc atttgtcgca gcatacaagt tataatcacg ctcaatgagg ctgtccaaga
      781 gatcatgagc gcccgatagt gtttgtccct gctgggcgag gtaaaattgg taacgctggg
      841 caagaaaact accgtctttt tcctgtccaa aatgagcaaa taaacgagaa aatcgcgtgt
      901 taaccagctc ttgtttactg attttcttca gctccaagtc tttccagaga gccttgttca
      961 taggaacgta ataatcttta taagcctgaa tatccgcaac tccttcttct tttagaagtt
     1021 gggtcaaagc cacatcctca gcagcatcaa aatcaagaag agtgtggtcg aggtcgaaga
     1081 gtagaaattt gtagaacaat ttgaggtttt cctttctgaa aattcattaa gaacattata
     1141 tcataaagca cctcatacaa ttaactaatt taatcactta aaaaaaattc gaacactttc
     1201 tatacaactg acagctcaaa tctttcagaa tagaacaata ctaactatcg agcaccccgc
     1261 cttcataaat atatgtgtaa ttctagacct agaattccta taaactaaat gctttcatac
     1321 tcttccaagt aattgattgc cttaaatttt aatttttgaa ggattctaaa gctagaatag
     1381 tcccatcaca atcagttttg attgattcac aatttagaaa cactatagtt tcactcctgt
     1441 taaaataaaa aggaactgca taaagcaatc cctttctgat tttgaaatca tttaccccca
     1501 attattcacc ccaaatctaa aaaccatcca gaatccttgc cttagcttag atcctggatg
     1561 gtttcttttt tcacccaatg ggtgtttttt actagacaaa aaagaatttc ccctttatgg
     1621 tataagtgta gaaaaaaaca caaaaagaaa ggaaactcac atgaacagtt taccaaatca
     1681 tcacttccaa aacaagtctt tttaccaact atctttcgat ggaggtcatt taacccagta
     1741 tggtggtctt atcttttttc aggaactttt ttcccagttg aaactaaaag agcggatttc
     1801 taagtattta gtaacgaatg accaacgccg ctactgtcgt tattcggatt cagatatcct
     1861 tgtccagttc ctctttcaac tgttaacagg ctatggaacg gactatgctt gtaaagaatt
     1921 gtcagctgat gtctactttc caaaattgtt ggaaggaggg cagcttgctt cacagccaac
     1981 cttatcccgt tttctttcca gaactgacga ggaaacagtc catagtttgc gatgcctcaa
     2041 ccttgaattg gtcgaattct ttttacagtt tcaccagcta aaccaactca ttgtagatat
     2101 cgattctacc catttcacaa cttatggcaa gcaagaaggt gttgcttata acgcccacta
     2161 tcgtgctcat ggctatcatc ctctttatgc tttcgagggg aagacaggtt attgtttcaa
     2221 tgcccagctt cgtcctggta atcgttattg ttctgaagag gcagacagct ttatcacacc
     2281 tgttttagaa cggtttaatc aacttctctt tcgaatggat agtggctttg cgaccccaaa
     2341 attatacgat ttaattgaaa aaacagggca atactacctc ataaaactca agaaaaatac
     2401 tgttctgagc cgtcttggag acctttccct cccttgccca caggatgaga acttaaccat
     2461 cttgccccac tccgcctact cagaaactct ctatcaagca ggatcttggt cgcacaagcg
     2521 tcgtgtctgc cagttctctg aacgaaaaga aggaaacttg ttctacgatg ttatttctct
     2581 cgttacaaat atgacgagtg gaacaagcca agaccagttt cagctttatc gtggacgtgg
     2641 tcaagccgag aatttcatca aggagatgaa ggagggattt tttggcgata aaacggatag
     2701 ttcaacctta atcaaaaacg aagttcgtat gatgatgagc tgtatc
//
LOCUS       DAVLTT010000110         2666 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLTT010000110 DAVLTT010000000
VERSION     DAVLTT010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2666
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.110"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            230..577
                     /gene="ssrA"
                     /locus_tag="VYN15_002053"
     tmRNA           230..577
                     /gene="ssrA"
                     /locus_tag="VYN15_002053"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(821..1597)
                     /locus_tag="VYN15_002054"
     CDS             complement(821..1597)
                     /locus_tag="VYN15_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000994488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1828 domain-containing protein"
                     /protein_id="HEV1453310.1"
                     /translation="MNATDIKNTYLNYIKENAVFNDVTDTHTEVITPFIDPLGEAIGF
                     SIKSNGKHLTVTDDGYTIWNLSINNIDVTKKGRRQDIFNSLLHFNGFDLHDGAIERTT
                     GKEHLGQVIHDMTQLLMNVYDFIQLTPNNIKSQFLDDVKSYFMKNEHYTVFPAFSIAG
                     KSRLEHRFNFVFMSKGISKIARVHNNITKQQVDTILASWLDTSEYRRKEYGDTEQLYI
                     IVSDEGYNNIKDDHQIALQEYGINILNFSDKEQLEIQLGK"
     gene            complement(1624..2094)
                     /locus_tag="VYN15_002055"
     CDS             complement(1624..2094)
                     /locus_tag="VYN15_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453311.1"
                     /translation="MKELLLTDSEAKALIKIIKAIANKHNRTLTNRSSGTINLVGKHD
                     TRFILNYFYSTTSKVFHLRETQHNYTLLRINLNNKFHKNANGEKVWGNRVNIFSEEEY
                     YQKGDETTHYKAYPLPYEDILNTDDFLDMLDNLLDYTNVNNPENIAINIQEDLL"
     gene            complement(2149..2613)
                     /locus_tag="VYN15_002056"
     CDS             complement(2149..2613)
                     /locus_tag="VYN15_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TM2 domain-containing protein"
                     /protein_id="HEV1453312.1"
                     /translation="MSKVVKVTGAEVVISHNEEYLKVNPSELNFVPKLGDEVEVHKVD
                     GEIIVIKVKDKKDDKININIVNENNAMQNQSQVVHTQEIATGVHYVNKWVYVILALFL
                     GGLGIHHFYAGYNGKGFLFLILSLTGIPAIIALFQGIIALFKKPDVYGRIAV"
BASE COUNT          779 a          439 c          457 g          991 t
ORIGIN      
        1 agtattttag aataattctc ttcgtgaatt tcttcaaaac agatagcttc atcttaggta
       61 tgtgttaatt ggatttcgta agctctattt acaatcgtaa agttatgcac tgaaaaagtt
      121 gtagttagtc ttccagtttg ctaaatttct cgaatagtat cttttttagg tatgtgattt
      181 ctttttgcat ttttgagtta gataaggtat aatggtttta ttgtcttttg gggtcgttac
      241 ggattcgaca ggcattatga ggcatatttt gcgactcgtg tggcgacgta aacgctcagt
      301 taaatataac tgcaaaaaat aacacttctt acgctctagc tgcctaaaaa ccagcaggcg
      361 tgacccgatt tggattgctc gtgttcaatg acaggtctta ttattagcga gatacgatta
      421 agccttgtct agcggcttga taagagattg atagactcgc agtttctaga cttgagttat
      481 gtgtcgaggg gctgttaaaa taatacataa cctatggttg tagacaaata tgttggcagg
      541 tgtttggacg tgggttcgac tcccaccggc tccattattc ctttgcattc ttttgcattc
      601 cttggtaaaa cgttgttaaa tcaacgtttt ttatttttat ctttggtatt cctttgcatt
      661 cttttgctaa aaagggagtc acaaacagac cctattttaa aaaaaggata gaaaaaagga
      721 tacaacattt gtcgcatcct agaaatctat gtacttcgta aagcgttctc cgattcgagt
      781 attcctctgc atgctttagt aaatatagga ttttttgtag ttacttccct aattggattt
      841 ctaattgttc tttatctgag aaattcaaaa tgttaatacc atactcttgt agagcgattt
      901 gatggtcatc tttgatatta ttataccctt catcgcttac aatgatatac aactgttctg
      961 tatctccata ttcttttcta cggtattcag atgtatctaa ccaactagct aagatagtat
     1021 caacttgttg tttggttatg ttattgtgaa ctctggctat ttttgaaata cctttactca
     1081 taaacacaaa attaaagcgg tgttctaaac gagatttacc tgcaattgag aaagctggaa
     1141 agactgtgta atgctcattt ttcatgaagt aagatttaac atcgtctaaa aattgagatt
     1201 taatattgtt aggtgttagc tgaataaagt cataaacatt catcagcaat tgtgtcatat
     1261 catgtatgac ttgtcctaga tgttctttac cagtcgtccg ttcgattgct ccatcgtgta
     1321 aatcaaatcc attaaagtgg agaagtgagt taaagatgtc ttgacgtcgc cctttttttg
     1381 taacatcaat attattaatg gataaattcc agatagtata accatcatct gtaactgtca
     1441 aatgttttcc attgcttttt attgagaaac caatagcttc acctaatggg tctataaaag
     1501 gagtaatcac ttcagtatga gtatcagtca catcgttaaa aacagcgttt tcttttatgt
     1561 aatttagata ggtatttttg atatcagtag cattcatgat attctccttt ctttataggg
     1621 tgattataac aaatcctctt gtatattaat tgctatattt tcaggattgt tcacattggt
     1681 atagtcaagc aaattatcaa gcatatccag gaagtcatca gtgttaagaa tatcttcata
     1741 aggtagtgga taggctttgt aatgagttgt ttcatcccct ttttgataat actcttcttc
     1801 agagaagatg ttaactcgat tgccccaaac tttctcgccg tttgcgttct tatggaattt
     1861 attatttaga ttgattcgta agagagtata gttgtgttga gtttccctta gatgaaaaac
     1921 tttgcttgta gtgctgtaga agtagttcaa aataaatcta gtatcatgct tgccaacaag
     1981 gttaatagta cctgaactgc gattcgtaag agttcgattg tgtttattag caattgcttt
     2041 aattattttt atgagagctt tagcttcact atctgtcaga agtaactctt tcatatcttt
     2101 cctttctact ttatctacat tctagagagt ggaaatctgg aatgtagatc agacagcgat
     2161 ccttccgtat acatctggtt tcttaaagag agctatgatg ccttggaaaa gtgcaataat
     2221 agcaggtatt cctgttaaag ataaaatcag aaaaaggaaa ccttttccgt tatatcctgc
     2281 gtaaaaatga tgtataccca atccacctaa aaataaagca agaataacat aaacccactt
     2341 attaacataa tgtacacctg tagctatttc ttgagtgtga acgacttgtg actgattttg
     2401 catagcgttg ttttcattga caatgttaat attaattttg tcgtcttttt tatctttaac
     2461 ttttatgacg ataatctcac catctacttt atgaacttcg acttcgtcac ctaattttgg
     2521 aacaaaattc aattcagatg gatttacttt taaatactct tcattatggg agattacaac
     2581 ctctgctcct gtaactttaa caacttttga cattttgttt ttcctttcat tttaccatct
     2641 atagatttta ataatgagct ttgata
//
LOCUS       DAVLTT010000111         2627 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLTT010000111 DAVLTT010000000
VERSION     DAVLTT010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2627
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.111"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..356
                     /locus_tag="VYN15_002057"
     CDS             <1..356
                     /locus_tag="VYN15_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nickase"
                     /protein_id="HEV1453313.1"
                     /translation="SAYSYLRKNNIETIGQLQTKIETLKSNSYRLNKKAKTIHKEMED
                     VEKKILYYEIYKAKKEVYEEYQKKNIFTKEAFYNKHKKDIDQYKVVSGKLKKLLSDKE
                     KLSPKKWNEEKILLM"
     gene            682..855
                     /locus_tag="VYN15_002058"
     CDS             682..855
                     /locus_tag="VYN15_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453314.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            1155..1568
                     /locus_tag="VYN15_002059"
     CDS             1155..1568
                     /locus_tag="VYN15_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEV1453315.1"
                     /translation="MNETLEKANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDL
                     KKELNKLGVSFSVMKNKESKNYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIK
                     KYKDLSKNKDKTKEKEKRKVKEKVKPNKKDMTREI"
     gene            1695..2399
                     /locus_tag="VYN15_002060"
     CDS             1695..2399
                     /locus_tag="VYN15_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV1453316.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEIVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEIEKDIEIDKKSTPIFYGEF
                     KNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLR
                     QKGLNKKMNYDVGESL"
BASE COUNT         1322 a          333 c          418 g          554 t
ORIGIN      
        1 caagtgcata tagttattta agaaaaaaca acatagaaac cataggtcag ttacaaacaa
       61 aaatagaaac tttaaagtct aatagttata ggctaaataa aaaagcaaag acaatccata
      121 aagaaatgga agatgtagaa aagaaaattc tatactatga aatctacaaa gccaaaaaag
      181 aagtttatga agaatatcaa aagaaaaata tattcacaaa agaagcattt tataacaaac
      241 ataagaaaga tatagaccaa tataaagtag taagtgggaa attaaaaaaa ctcctatcag
      301 ataaggaaaa actaagtcct aaaaagtgga atgaagaaaa aattctttta atgtaaaatc
      361 ttgaagaaat aaataaagaa aaagacaaga taaaagatga ataccaggaa attaatcata
      421 taaaatattc agtagatttt gtaaacaaag aacttggtat agatttatcc atagaaatag
      481 ataagctaat aaaacaggga gaaaaaccaa gtgtaatagc acagattaaa aagttccaag
      541 accaagtcaa taaagataat gaatacagag aaatgatgaa aaacaagaaa atggatcaag
      601 aaagataaga cctggtaaaa atatcttatc caagctataa tatgaccaaa caactaaagt
      661 cagatctagg aggtaataga gatgaataaa aggcaagagc taatagatga actcataaaa
      721 gcaaatgaag atggaacata caaaacctat aaaagcacag aagaaataaa agcaatgaac
      781 aatgaagaaa tacagattat atattccaac atgaaaaact atctatcaga caaaagaaca
      841 cacataaact attaaaggtg gaaaggtagt gtaagctatt tttaaaagta taaaaggtac
      901 aaagacctaa gaaatatata aaaacatcaa aataaagtat tccaccacca agaacaataa
      961 aataaaaaca agcaaaggga agtatagaaa aattaaaacc tatacttccc ttttttaatt
     1021 caaacaaagg agagaaaagc atgataaacg aagaaataag caaggaagca ggtcaagcag
     1081 cacaaaccat aatatcatac acaataaagg caacaaaaga atcaatcaat ttataaaaag
     1141 aaataagaaa aaagatgaat gaaactttag aaaaagcaaa tggaaactta aaaagtctta
     1201 tgggcgatga aatgaaaata aaagacctct acaagaaagg acaactagaa aatataagca
     1261 tagatcaaat cgacctcaaa gacttaaaaa aagaactaaa caaacttgga gtaagtttct
     1321 cagtaatgaa aaacaaagaa agcaaaaact atgaaatatt cttccaagcc aaagacataa
     1381 aagtaatgga atatgccttt aagcaagtca tagccaagga aaataaaaaa gaaaaagaaa
     1441 gtatcctaaa acaaataaag aaatacaaag acctatccaa aaacaaagat aagacaaaag
     1501 aaaaagaaaa aaggaaagta aaagaaaaag taaaaccaaa caaaaaagat atgaccagag
     1561 aaatctaaag ggagtaacga aaagttacac ccttaaataa ccataataac aagacttccg
     1621 aaaaacagaa gttcagaatt ccgaaaatcg gaaatcaaga atttcgatta tcgaaaatca
     1681 agaaaggagc agatatggca acaaacaaaa gatactattg gataaaatta aaagaagaat
     1741 ttttcacaga caaaaggata aaaaggttaa ggagaatatc tggaggagat acctatacga
     1801 taatctacct aaaacttcta ctactaagcc taaaagatga gggcaaactc tattatgacg
     1861 gagtagaaag tgattttata aaagagttag cactaaccat agatgaaaca gacgatgatg
     1921 taatggtaac agtaaattat ttaatcaatc aaggcttatt agaaattgta acagaaaatg
     1981 atgaatacta cctaactgaa ataccaaact taatcggatc agaaacagcc tgggcagaga
     2041 aaaaaagaag atacagacaa aataaacaga ggacattgtc cttaatgagt ccaacccatg
     2101 tccgacaaga gatagagata gagaaagata tagagataga taaaaagtcc acccccattt
     2161 tttatggaga atttaaaaat gtaaggttaa gcaaagaaga atataaaaat ctaaaagaaa
     2221 aattaaactc gcacacagat ataatgataa ataaactatc cagatacatg gaaagcagtg
     2281 gtaagaccta tcaaaaccac tatgtgacaa tcttaaaatg gtatgaagaa gataaagaca
     2341 aactaagaca gaaaggttta aataaaaaaa tgaattatga tgtaggagaa tctttataga
     2401 taaaaagagg tggaaaggca ctattaaaga ctttaagtct aaaaaggtat caaagtatgc
     2461 cagagataaa aaaatataaa tatgacactt taagggcgat tagaaaatta aagaaatgct
     2521 agaagacttt tagatgacag ttaccaagaa ggtctaattt tcactgctac ttatgcagtg
     2581 aaaattagac ctttttatat aagcaaattc tatttcaaaa ttggtta
//
LOCUS       DAVLTT010000112         2608 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLTT010000112 DAVLTT010000000
VERSION     DAVLTT010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.112"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            120..2444
                     /gene="pflB"
                     /locus_tag="VYN15_002061"
     CDS             120..2444
                     /gene="pflB"
                     /locus_tag="VYN15_002061"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV1453317.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
BASE COUNT          822 a          547 c          527 g          712 t
ORIGIN      
        1 gttttagaaa agaaagtgta aaaataggga attttcactt gttgaaatcg gttactatat
       61 ggtatacttg tcttatgaat gtaacagatg actgttacta gaaaaaagag gacattaata
      121 tggttgttaa gacagttgtt gaagcacaag atatttttga caaagcttgg gaaggcttca
      181 aaggcgtaga ttggaaagaa aaagcaagtg tatcacgatt tgtacaagct aactacacac
      241 cttatgatgg agacgaaagc ttccttgcag gaccaacaga gcgttcactt cacatcaaga
      301 aaattgtaga agaaactaaa gcacactacg aagaaactcg tttcccaatg gacactcgtc
      361 caacatctat cgctgatatc cctgctggat ttatcgacaa agaaaatgaa gttatcttcg
      421 gtatccaaaa cgatgaactc ttcaaattga acttcatgcc aaaaggtggt atccgtatgg
      481 ctgaaactac tttgaaagaa aatggatacg aaccagaccc agctgttcac gaaatcttca
      541 ctaaatatgt aacaacagtt aacgacggta ttttccgtgc ctacacttca aatattcgtc
      601 gcgctcgtca cgcacacact gtaactggtc ttccagatgc atactcacgc ggacgtatca
      661 tcggtgttta cgcacgtctt gctctttacg gtgcagacta cttgatgcaa gaaaaagtaa
      721 atgactggaa tgcaatcaaa gaaatcgatg aagaaacaat ccgtcttcgt gaagaagtaa
      781 accttcaata ccaagcattg caacaagttg ttcgcctggg tgacctttac ggggttgatg
      841 ttcgcaaacc agcgatgaac gtgaaagaag caatccaatg ggttaacatt gctttcatgg
      901 ctgtctgccg tgtgattaac ggtgctgcta catctctagg tcgtgtacca atcgtattgg
      961 acatatttgc agaacgtgac cttgctcgtg gtacatttac tgaatcagaa atccaagaat
     1021 tcgttgatga tttcgttatg aaacttcgta cagttaaatt tgctcgtaca aaagcttatg
     1081 accaattgta ctcaggtgac ccaaccttta tcacaacttc tatggctggt atgggtaacg
     1141 acggtcgtca ccgtgttact aagatggact accgtttctt gaacactctt gacaacatcg
     1201 gtaactcacc agaaccaaac ttgacagttc tttggactga caaattgcca tacaacttcc
     1261 gtcgctactg tatgcacatg agccacaaac actcttctat ccaatacgaa ggtgtaacaa
     1321 caatggctaa agacggatat ggtgaaatga gctgtatctc atgctgtgtg tctccacttg
     1381 atccagaaaa tgaagaacaa cgccacaaca tccagtactt cggtgctcgt gtaaacgttc
     1441 ttaaagccct tcttactggt ttgaatggtg gttacgacga tgttcacaaa gactacaaag
     1501 tatttgatat cgaaccaatc cgtgacgaag ttcttgaatt tgaatcagtt aaagcgaact
     1561 ttgaaaaatc tcttgactgg ttgactgaca cttacgtaga tgccttgaac atcatccact
     1621 acatgactga taggtacaac tacgaagctg ttcaaatggc cttcttgcca actaaacaac
     1681 gtgccaacat gggattcggt atctgtggat ttgctaacac tgttgataca ttgtcagcta
     1741 tcaaatacgc tacagttaaa ccaatccgtg acgaagatgg ctacatctac gattacgaaa
     1801 caatcggtga ctacccacgc tggggtgaag atgacccacg ttcaaacgaa ttggcagaat
     1861 ggttgatcga agcttacaca actcgtctac gtagccacaa actatacaaa gacgcagaag
     1921 ctacagtatc acttttgaca atcacatcta acgttgctta ctctaaacaa actggtaact
     1981 caccagttca caaaggtgta tacctcaacg aagatggttc tgtgaacttg tctaaacttg
     2041 aattcttctc accaggtgct aacccatcta acaaagctaa aggtggttgg ttgcaaaact
     2101 tgaactcact ttctagcctt gactttagtt atgcagctga cggtatctca ttgactacac
     2161 aagtatcacc tcgcgctctt ggtaagactc gtgatgaaca agttgataac ttggtaacaa
     2221 tccttgatgg ttacttcgaa aacggtggac aacacgttaa cttgaacgtt atggacttga
     2281 acgatgttta cgaaaaaatc atgtcaggcg aagacgttat cgtacgtatc tctggatact
     2341 gtgtaaacac taaatacctc actccagaac aaaaaactga attgacacaa cgtgtcttcc
     2401 acgaagttct ttcaatggat gacgccttgg atgcattgag ctaatcaagt tcttgaataa
     2461 taaaaaggaa ccctcggtca aacgactgag ggttttgtgc ttgggatagt atgagcaatt
     2521 ccttcggcgc aatatgcaat gtttttgggc tctttgtcaa ctgtagtggg ttgaaaaaaa
     2581 gctaagcttg agaaaggaca aatttcgt
//
LOCUS       DAVLTT010000113         2595 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLTT010000113 DAVLTT010000000
VERSION     DAVLTT010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2595
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.113"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            470..640
                     /locus_tag="VYN15_002062"
     CDS             470..640
                     /locus_tag="VYN15_002062"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1453318.1"
                     /translation="MTKQIPKFTKDTAQLYTCKWLLYNKVTKMYDHTIVNHSVREYIT
                     DSISTNTIEEAE"
     gene            1252..1536
                     /locus_tag="VYN15_002063"
     CDS             1252..1536
                     /locus_tag="VYN15_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453319.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            1529..1767
                     /locus_tag="VYN15_002064"
                     /pseudo
     CDS             1529..1767
                     /locus_tag="VYN15_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1863..2081
                     /locus_tag="VYN15_002065"
     CDS             1863..2081
                     /locus_tag="VYN15_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453320.1"
                     /translation="MMSIREQDLKDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
BASE COUNT          985 a          432 c          392 g          786 t
ORIGIN      
        1 gttgtagata gaactgacga agtcagtaac atctatacgg taaggcgacg ctgatgtggt
       61 ttgaagagat tttcgaaaag tattagttaa atcttgttta atatctctac accatactat
      121 tttacatata ttatttagcg ccacatagta ctgaactctc tccaaaaacg gttatgcctc
      181 tttgaatagg gcgttatcac aagaaaagca tctccacgtt tcaacttcat atggctcaaa
      241 aacaatcaat tgatgctaaa acctgtacct agatgtttcg gttcataaaa ccataaaact
      301 gtaaaagtgg atgaaattga tagcgatagt caaatcaaga ggcatcataa ctctaaaaag
      361 tcacaatata taagttcatc ctcggaaaaa tatcattcta attgttgaaa tgcctacatg
      421 aaaagaaacg tcaaatgctc atgaaacaac gaatacaggt atcaaaacta tgacaaaaca
      481 aatccctaaa tttactaaag acactgctca actttacacc tgtaaatggt tgttgtataa
      541 taaagttaca aagatgtacg accacactat tgtaaatcat agtgttcgcg aatatattac
      601 tgatagcatt tctacaaata caattgaaga ggctgaatag gctttaaacg aaatatgtca
      661 gtgttttggc attcctagcc ttcatatcat ttaaagaatt gtatagataa aattttttcc
      721 aatacagaca ctcgtaacaa ctgcttcatt tttctaccaa catatttagg aacaggataa
      781 gatacaagag gattaatcca tagctcagtt ctataccaat ctaagacaaa taagctaaaa
      841 aaacgattga taataagcaa atagattcca aattttctct atctgctcat tttaataaac
      901 aatactagtg taactatcct tccagtcaga agcttgtcaa atcacaccga aaattcttct
      961 aaaatttatc tcgttaggca atcaagcaaa aactcgacga tagtacaaac attatcatac
     1021 agaattgact tcctaaatta tatactttag taaggttttc ggataagaaa aaaggttcat
     1081 tttacatttc taaacattct tttctaagat gaaaaacaga atttttcgat tgtaatttaa
     1141 agcaacaaga agattttcag tatcatccta tagatacgag ctaattaaga aaaactacat
     1201 ttttgaatat aaactacaat aatataaact aaattccata ggaggaagac aatggattgg
     1261 tacgattata tgatacaggc atccaaacaa tcacaattca acgcaagcca ttggtttcgc
     1321 tatttgcgaa aagttatttt tgaagactat tcttatttaa caaaccaaga tgtagaaaag
     1381 ttgctagact ccaaagaact aacccgtttt caaaaaatta gcttgaagta tgcctttcaa
     1441 gagcatactc caactcataa atatgtgatt tcattaaata aacctgctaa gttaaccaat
     1501 gttcaaaaat tgatggagaa atacaaacat ggataaaatg aaaccggtct tccaagccct
     1561 aaataagaaa ttaattcagg aaaatctgac tttaacaatt atggttatgt cttagaatat
     1621 catggtttac gtgccacaca agatgttgat gctttttatg accaaaatca gaaaatcaat
     1681 gaaattattg ctcgtgtagg aaaacagttt aatcttaaca tccacgaaga gttatggctc
     1741 aacaatcatg ttgcaaagca aatatgaaca aacaacctcc cttaagttta tgcgaatcct
     1801 tgtactcatt tgagaatctg accgttttag tagtccctat tgagtatgtg ttaggaatga
     1861 agatgatgag tatcagagag caggatttga aagatattgg tgcaattatt aaatacaaaa
     1921 actttcattc accattcgat acctttaaat atttaaaaga tatgggattt gatactattg
     1981 acctctctgt tctattagaa ggttttagtt atgcttatgg tatggattgg ttagaaaaat
     2041 tttttaaaga aaatcaagat aaacttcgcg aattttatta acagtatcaa acaagatgat
     2101 tgtcaattag ccagtcgtct tgtttttatg atggaatgaa ataaaatcgg aacaaatcac
     2161 ttagagaatt ccagacaatt tctagcactg tttgagacgt ttcagcggac tatagcaaaa
     2221 tgaaataaga ataagacaaa tcgatcagga cagtcaaatc gatttctaag aatgttttag
     2281 aagtaaaggt gtactattct aatttcaatc tactatattt cagattcggt ccactattcc
     2341 ttcccaaaaa caggctctat aatatttgta gtgggtaaat ccactataga tattatggag
     2401 cctattttat tgtagaaaaa aagtcccata agatctataa tgaaaagcga tcaaacaact
     2461 cattagaaag attcatatgg gacaattaca ttttatcaca aaactactcg atatcaaaga
     2521 cacaaatatc caaattatag atgtcgtcaa tagggattca cacaaagaaa tcatcgccaa
     2581 actggactac gacgc
//
LOCUS       DAVLTT010000114         2444 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLTT010000114 DAVLTT010000000
VERSION     DAVLTT010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2444
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.114"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(382..1275)
                     /locus_tag="VYN15_002066"
     CDS             complement(382..1275)
                     /locus_tag="VYN15_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1453321.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(2029..2259)
                     /gene="blpU"
                     /locus_tag="VYN15_002067"
     CDS             complement(2029..2259)
                     /gene="blpU"
                     /locus_tag="VYN15_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV1453322.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAATCWW"
BASE COUNT          811 a          506 c          263 g          864 t
ORIGIN      
        1 tagattatca aattactttt atatcactaa gactcaataa aagataatgt ctatttaact
       61 tttatacgat tactacctct ttttagttta cacttcctac atcataaata aacatactca
      121 accctcacaa tctccaaata actcttctat atcattgaaa attgagtttc atcctctata
      181 ctaatgtagg acattccttt aatccaatat aagaatacct tgttccatta atctctaccc
      241 gatattatag atagaaccaa attcctatac ttaaaaggac aaataacgtt ccaaccataa
      301 taaacctcct ttctttttga gaacgttttc tttataggtt tagtatagca aaaacatgaa
      361 aaaaacaaca tgacttagaa gtcaggttgt tgggaaatct atctgttttt ctgctaaaat
      421 tctctgaact aatacctgat cgtctagcaa ttctgctaga gaaatcgcct tttcatagaa
      481 actttctgcc tctaaaatat tcttgtctac aaataaagca tattttgcct ttagcaaaaa
      541 tagatgaggt cggtaaaaaa catgtcttgt tttagcaata attttctcaa atgtttgaat
      601 atatatcaga ctatcctctg tctgaatttg gataaatagg ctcagaagaa ctttttccat
      661 ttgaactagg ctagccttat cttcatattc tgaacatagc aatacttttt gagctaactc
      721 ctcaaaatgt tctttatctt ctaatcccat agcacaacaa aagaaataca attcaataat
      781 caacaaatca tttacagaaa aatatttctt ttttaataac tgctggaaat attcttccac
      841 taaccctaaa ccgtaggtca catctgaact accataaata tcaaaacgag cttgtgtcac
      901 atccacaatt aactgctctt cctcaggcaa attctcataa tagttttcat atatttcctc
      961 aagtatagct tcttttcgtt cgattcttcc cttatcagcg taggtttgag aatgaatcag
     1021 ctcatctttg agttttagga atccttttgg aatctctata accttaacat ccacaatatt
     1081 ctgtaatgat actccaagtt tatccgcaat caataataat ttaggaagtg ttgctaaagc
     1141 ttgcccattt tcaatacgtg ctagctgacg aatcgtcaac tctgattcat caccacaaat
     1201 atctatctga gtttttccac aagatcgcct aatagttttg attttataac caatttcacg
     1261 tttcaactca tccatagtaa tactccttaa gttgattaca aagatttctt tttcttccta
     1321 attcttttgt caatcatata taaaacgata agcgaaaaca gcggtagaac aatataactc
     1381 ttttcactca ttatcagctg aaatcccagg gttgctagta tcttaaagat gaaaatattc
     1441 atcaaaaata gaaaaacaaa tactaaaaaa tattttaaaa ccttcttcat ttcttttctt
     1501 caactttcct aatttctaca cctattttat cgaaaatata tataaaactc caaataaaca
     1561 cttcgactgc actttttttg gcaaaaaata gacagaacaa acatcctacc tactaaaaat
     1621 atgatatgaa aggaaaatga ttttttactg acaccctagg caagcttggg acaaataaat
     1681 cattgatagc aacatttacg acatcctatt taaagttcct tcaatttcta atgtccccgc
     1741 tatttctaag ccacctctgg tatgatctat tcctagtcag aatagataac accgttctaa
     1801 attacgattc atagttactc cttttttgac tcgttactat aagactccta tttacatgcg
     1861 caaaataatt ttgattcaga ttcatcattt atagttttga ttatttttta acagattttt
     1921 ctgttttctt ctccgaagac tttaaaaatt tttttctaat taaatcatcc atataaggac
     1981 caaatatacc aactactaaa ccaataataa aacttttaaa atccataatt accaccaaca
     2041 tgtcgctgca taggccacac ctccaagtat agctcctccc acagcaccag ttgctgcacc
     2101 ttgccatgtt cttgttttaa ttcctagctg aagacctcgt actgctcctc ctccaacacc
     2161 tgctttggca aaatctcccc aattgcatcc gccaccttca acgcaagcaa gcatctcagt
     2221 atccataatt tcaaattgtg acatcttttt tgtattcata acgaatacct cttttttatt
     2281 tttaatattt gtcttgttac aaacttgaca agtttagtat aacagtatct attaattttt
     2341 ttcatccaaa tcttgaattg gcatcgaaac gtcttgaatt agcttttttg tttcaaaatc
     2401 atctctattt ttaaaaaaga tgttttctaa tcactttttt acta
//
LOCUS       DAVLTT010000115         2121 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLTT010000115 DAVLTT010000000
VERSION     DAVLTT010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2121
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.115"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(<1..1883)
                     /locus_tag="VYN15_002068"
     CDS             complement(<1..1883)
                     /locus_tag="VYN15_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HEV1453323.1"
                     /translation="MFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASISISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYVASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIA
                     KSETKVYTGEGVDSVYHVPIYYELTVINDGSKLTFTYTVTYVNPKTKTLGNISKMGPG
                     YSIYNTGTSTQTMLTLGSGLGKPSGVKNSITDKNGVQVQYYNMSTMTKRGSGYTWGNG
                     AQMNGLFAKRGYGLTSSWTVPITGTDTSFTFTPYAAKTDNIRTNYFNGGGKVVESSTT
                     SQSLSQSKSLSVSASQSASASASTSASASASTSASASASTSASTSASTSASESASTSA
                     SASASTSASESASTSASASASTSASASASTSASESASTSASESASTSASESASTSASA
                     SASTSASVSASTSASASASTSASASASTSASASASTSASVSASTSASESASTSASASA
                     STSASASASTSASASASTSASASTSASASASISASESASTSASASASTSASASASTSA
                     SASA"
     gene            complement(1881..1994)
                     /locus_tag="VYN15_002069"
                     /pseudo
     CDS             complement(1881..1994)
                     /locus_tag="VYN15_002069"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
BASE COUNT          547 a          453 c          490 g          631 t
ORIGIN      
        1 gctgaagccg atgcacttgt tgacgctgat gctgaggcgc tagtacttgc tgaagcggac
       61 gcactcgttg atgccgattc agacgctgag atacttgctg aggctgatgc actggttgag
      121 gctgaggcgc tagtacttgc tgaagccgat gcactggtgc ttgctgaagc cgatgcactt
      181 gttgatgcgg aagctgacgc actggtactt gctgactctg atgcactggt tgacgctgag
      241 actgaagcac tcgttgatgc tgaagccgag gcactggtac ttgctgaggc tgacgcactc
      301 gttgatgctg aagctgaagc actggtgctt gctgagactg atgcgctggt acttgctgaa
      361 gctgaagcac tcgttgatgc tgactcagac gcactcgttg acgctgactc agacgcactg
      421 gttgacgctg attcagatgc tgaggtgctt gctgaggccg aggcgctggt tgaggctgaa
      481 gctgaagcac tggttgatgc agattcagag gcacttgttg acgctgaagc tgaagcactg
      541 gttgatgcag attcagaggc actcgttgag gctgaagtcg aggcgcttgt gcttgctgag
      601 gctgaggcgc ttgtgcttgc tgaggctgag gcgcttgtcg atgctgaagc tgaggcgctt
      661 tgactagcac ttactgagag tgacttagac tgtgaaagtg actgactggt cgtgctagat
      721 tcaactacct ttcctccacc attgaagtag ttagttctaa tgttatctgt tttagcagcg
      781 taaggggtaa atgtaaagga tgtatccgtt ccagtaattg gtacagtcca agatgatgtt
      841 aatccatatc ctcgcttagc aaataaacca ttcatttggg caccatttcc ccaagtatac
      901 ccactacccc gcttcgtcat tgtagacata ttatagtatt gaacctgtac accatttttg
      961 tcagtaatgg agttctttac acctgaaggt ttaccaagac cactgccaag ggttaacatt
     1021 gtttgtgttg aagtacctgt attatagata gaatacccag gacccatctt tgatatatta
     1081 ccaagagtct ttgttttagg attcacatac gtaaccgtat aggtaaaggt caattttgaa
     1141 ccatcattta tcactgtcaa ttcatagtaa attggaacat gatataccga atctacacct
     1201 tcacctgtat aaacttttgt ctcactttta gcaatgttta gacttgcatt aattgcaggg
     1261 gcgccattta caatcgtatt gccagaaaaa acagcagctt ttatagaagc cagcaattgc
     1321 tcgatggaat ccactgaacg cttgcgtcgc ttagcataag attggagatt gacatttgta
     1381 actgatgcta cataatcact agctggtttc ttacgatctt cttcgacctt cttagcagtt
     1441 gcttctgtag cggcagctgt ttgtgatcct accacagtag atgatgcaga gatacttatc
     1501 gaagccgatg tacttgctga ttctgatgca cttgtactcg ctgaggtcga agcgctggtt
     1561 gaggctgact cagatgcaga tgtacttgcc gactctgaag ctgacaaact agttgaactc
     1621 gctgaattac ttgtagatat cgtacctaga actactgtat catttgttgc caaagcatcc
     1681 gttttctcta cagttttttc aagtactgcc gactcatttg taaatacctt cgtttgagtt
     1741 gcaacggttc cacttatgac agttcccgca gcaactattc ccttgaggat atcaagccca
     1801 gtaattgaat gacttacttt atcttctacc gtttcggtca tgacctgagt agtatcaaca
     1861 ccaccacgca tgaccttaaa caagccaaaa agagaagtcg aggcccgtag ccaatgcttc
     1921 cctgatttga ttaatttgaa ccgagttact cggtctgttt ctctatattc acccttctga
     1981 cgtctaaaaa atattttgaa atttcctttc gagtattatt ttcatgtatg gatataaata
     2041 aattaccata ctataattat agaataggga acccaaaata gcaagaaact tgaggtattt
     2101 ttgctaaaaa aaaaaagcat t
//
LOCUS       DAVLTT010000116         2118 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLTT010000116 DAVLTT010000000
VERSION     DAVLTT010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2118
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.116"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            138..1754
                     /locus_tag="VYN15_002070"
     CDS             138..1754
                     /locus_tag="VYN15_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1453324.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKRIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT          753 a          247 c          379 g          739 t
ORIGIN      
        1 gtaatcaaga aggcaagaga agaaaaaatt tttaacgaat ttctttttta aaatatatgt
       61 tattatataa ttttggtttt ttctattgta tatatgacaa ctatgttcaa ttaaaattta
      121 gaaagtgaga aactattgtg tatactatta taaaatcaaa tataaaaaaa tttagtttat
      181 taacgatatt tattgttgct ggtcaattat tgctaattta tgcagcaact attaatgctc
      241 tggtgttgaa tgaattaatt gcgatgaatt tagagcggtt tttgaaattg tcaatctacc
      301 aaatgattgt ctggtgtggg ataatattcc ttgactgggt agtgaaaaat tatcaggttg
      361 aagtgatcca agagtttaat ctagagattc gaaatagagt tgccacagac atctctaact
      421 ctacctatca agaatttcat agtaaatcat caggaacata tctttcgtgg ctaaataatg
      481 atgttcagac tttaaatgat caggctttta aacaactttt tttagtaata aaaggaattt
      541 ctggtactat atttgcagtt gtgactctta atcactatca ttggtcattg actgtagcca
      601 ccttgttttc attaatgatt atgctacttg taccaaaaat ctttgcatcg aaaatgcgag
      661 aagttagtct aaatttaact aaccaaaatg aagctttttt aaaatctagt gagactatat
      721 tgaatggatt tgatgtgtta gcgtccttga atcttttata tgtattgcct aagaaaatta
      781 aagaagcagg aattttatta aagatggtta tacaaagaaa gacaactgta gaaacgttag
      841 caggcgctat tagcttcttt ctcaatattt tttttcagat atctctcgtt tttttaacag
      901 gctatcttgc aataaaagga atagtgaaaa ttggtactat tgaagcaata ggagcactaa
      961 caggtgttat ttttacagcg ctaggtgaat taggaggtca attatcctct attattggta
     1021 cgaagcctat ttttttaaaa ttgtattcaa ttaatccaat tgagtcaaat aaaatgaatg
     1081 atatcgaacc aaatgaggtg aatagagatt ttccgttata tgaagcaaaa aatatttgct
     1141 ataagtatgg agataaagaa atattaaaaa acttaaattt ttgttttcaa cgtaatgaaa
     1201 agtatttaat tttaggtgaa agtggaagcg ggaaatctac attattaaaa ttattgaatg
     1261 gctttttgag agattatagt ggagaattgc gattctgcgg ggatgatata aaaaaaacct
     1321 cctatttaaa tatggtttcg aatgttctat atgtagatca aaaagcttat ttgtttgaag
     1381 gtacgattag agataatatt ttattggaag aaaattatac tgatgaagaa atactacagt
     1441 ctttagagca agttggtttg agtgtaaaag attttcctaa taacatttta gattattatg
     1501 ttggtgatga tgggagatta ctatcaggag ggcagaaaca aaaaattact ttagctagag
     1561 ggctaattag aaataagaga atagtattaa ttgacgaggg aacttctgct atcgatagga
     1621 gaacttcgtt agcgattgaa cgtaagatat tagatagaga ggatttgact gtcattattg
     1681 ttacccatgc tccgcatccg gaacttaaac aatattttac taagatatat caatttccaa
     1741 aggattttat ttaagaatat aggggaggga aacatgagat tctattgtga agcttatgag
     1801 gtaattactg aagagaaaaa agtatcattt tttatgtaga tgaaaaaccc ttaaggtatc
     1861 tgttatttga ctatatattt ctactagttc tagctaaaaa aaaatatccc aatcttatga
     1921 actgcacccc aaaagttaga tttattctgt ctaacttttg gggtgcagtt cattttgcat
     1981 agttttggca ttcatcctag atatccatat aaaatgtctg agattgttga aatgtctaaa
     2041 aaaatatcaa atctaaacga taaaaaagaa tttcacaaaa agaactgtga gttgaggttt
     2101 caagatagtg ttcttgat
//
LOCUS       DAVLTT010000117         2031 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLTT010000117 DAVLTT010000000
VERSION     DAVLTT010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2031
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.117"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            15..251
                     /locus_tag="VYN15_002071"
     CDS             15..251
                     /locus_tag="VYN15_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HEV1453325.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKSISHEEMMRRYG"
     gene            244..975
                     /locus_tag="VYN15_002072"
     CDS             244..975
                     /locus_tag="VYN15_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1453326.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLYYDTITQKYHFL"
     gene            complement(1086..1169)
                     /locus_tag="VYN15_002073"
     tRNA            complement(1086..1169)
                     /locus_tag="VYN15_002073"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1133..1135),aa:Leu,seq:caa)
     gene            complement(1179..1250)
                     /locus_tag="VYN15_002074"
     tRNA            complement(1179..1250)
                     /locus_tag="VYN15_002074"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1216..1218),aa:Gln,seq:ttg)
     gene            complement(1261..1333)
                     /locus_tag="VYN15_002075"
     tRNA            complement(1261..1333)
                     /locus_tag="VYN15_002075"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1298..1300),aa:His,seq:gtg)
     gene            complement(1348..1418)
                     /locus_tag="VYN15_002076"
     tRNA            complement(1348..1418)
                     /locus_tag="VYN15_002076"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1384..1386),aa:Trp,seq:cca)
     gene            complement(1423..1503)
                     /locus_tag="VYN15_002077"
     tRNA            complement(1423..1503)
                     /locus_tag="VYN15_002077"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1467..1469),aa:Tyr,seq:gta)
     gene            complement(1516..1588)
                     /locus_tag="VYN15_002078"
     tRNA            complement(1516..1588)
                     /locus_tag="VYN15_002078"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1553..1555),aa:Phe,seq:gaa)
     gene            complement(1592..1665)
                     /locus_tag="VYN15_002079"
     tRNA            complement(1592..1665)
                     /locus_tag="VYN15_002079"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1629..1631),aa:Met,seq:cat)
     gene            complement(1676..1765)
                     /locus_tag="VYN15_002080"
     tRNA            complement(1676..1765)
                     /locus_tag="VYN15_002080"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1727..1729),aa:Ser,seq:tga)
     gene            complement(1849..1922)
                     /locus_tag="VYN15_002081"
     tRNA            complement(1849..1922)
                     /locus_tag="VYN15_002081"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1886..1888),aa:Ile,seq:gat)
     gene            complement(1957..2027)
                     /locus_tag="VYN15_002082"
     tRNA            complement(1957..2027)
                     /locus_tag="VYN15_002082"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1993..1995),aa:Gly,seq:tcc)
BASE COUNT          670 a          415 c          394 g          552 t
ORIGIN      
        1 taggtggctg ttatatgaat aatgttgtta ctacacaaat ttctattcaa cttagtcaag
       61 agttaaattc tttattaaat gctattgttg aagaaaataa tacaacaaag actgacttta
      121 ttagacaagc tgttatagag aaaattgaag atatgtatga tattaaggtc gctgatgaag
      181 cttataaaaa atgggttgaa tgtggcaaaa aatctatctc acatgaagaa atgatgagac
      241 gctatggcta aattatacgc aatatctgat atacatggat acttggatga attcagagac
      301 gctctcaata aagtaaattt aaacgataaa gataatcgcc tatttttact aggagattat
      361 cttgataatg gacttcaatc ttttcaagtc atttccaaaa taatcgaact tgaggaggtt
      421 tatcctaatc aaattattac tcttctaggg aatcatgaag aatggtttta tgattggttg
      481 attttagata aacctactgc ttcagcattt ccagaaacaa taaaaagctt cttctctcca
      541 gaggaattga actatatttt taaatcgaat gctaacaact ttgaaacagg tgttagaaat
      601 gaaattaaaa ataatatcaa attcaaccca tttataaact ggtttaaaaa gcgatatagg
      661 gataaacgct attatgaaac tgatacccaa atttttgttc atgcaggcat tgatgaagaa
      721 gcaggaatgc tttggaaaga actaacgagt tcaaagatat ttacaaacaa atttccaatt
      781 accactggta gatttcataa agctattatt tcgggccata ttgcttcttg ggaagtagct
      841 aaagatagaa gatacctagg taagatttac tatgatagta aaagtcatta cttaattgat
      901 ggagatgtaa cgaatagcaa aacaatacct gttctttact atgatacaat tacccaaaaa
      961 tatcactttc tataactttt aatcatgtgc ttttatatga aattagtaat tattagtaac
     1021 aattccaaga aatttcttat gacataacaa aaagacaagg tcctaaaacc ttgtctttaa
     1081 tactataccg gcggccgggg tcgaaccggc acgtccttgc ggacactgga ttttgagtcc
     1141 agcgcgtctg ccaattccgc cacgccggca aatagtaact ggggtagctg gattcgaacc
     1201 aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca atataaaata
     1261 ggcgagtgat ggggatcgaa cccacgcatg ccagagccac aatctggtgt gttaaccact
     1321 tcaccacacc cgccataatt ctattaacac gggcagtagg aattgaaccc acactgaagg
     1381 ttttggagac cttagttcta cctttaaact atgcccgtaa aatggaaggg gagggattcg
     1441 aacccccgaa cccgaaggag cggatttaca gtccgccgcg tttagcctct tcgctaccct
     1501 tccaaaatat ataaatggcg cgagacggaa tcgaaccgcc gacacatgga gcttcaatcc
     1561 attgctctac caactgagct accgagcctt attgcgggag caggatttga acctacgacc
     1621 ttcgggttat gagcccgacg agctaccgag ctgctccatc ccgcgttaat ataaaaggag
     1681 gatgtgggat tcgaacccac gcacgctttt acacgcctga cggttttcaa gaccgttccc
     1741 ttcagccgga cttgggtaat cctccaaaat agttttatac gggaacaagc ccgtgtcctc
     1801 ttagtgaaca gataatattc caatccccta gtaatggact aaacactatg ggcacgagtg
     1861 gactcgaacc accgacctca cgcttatcag gcgtgcgctc taaccacctg agctacgcgc
     1921 ccaagtcaaa aacttggtac aaagaacaaa gttcaaagcg ggtgacgaga atcgaactcg
     1981 cgacaacagc ttggaaggct gtagttttac cactaaacta cacccgctaa a
//
LOCUS       DAVLTT010000118         1994 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLTT010000118 DAVLTT010000000
VERSION     DAVLTT010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.118"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..92
                     /locus_tag="VYN15_002083"
     CDS             <1..92
                     /locus_tag="VYN15_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="multidrug ABC transporter ATP-binding protein"
                     /protein_id="HEV1453327.1"
                     /translation="IEVSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            107..847
                     /locus_tag="VYN15_002084"
     CDS             107..847
                     /locus_tag="VYN15_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1453328.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            850..>1994
                     /locus_tag="VYN15_002085"
     CDS             850..>1994
                     /locus_tag="VYN15_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453329.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLL"
BASE COUNT          652 a          258 c          366 g          718 t
ORIGIN      
        1 ttattgaagt ttcacatcat tatgacttaa atgacaagag atacactgat atatataaat
       61 tggaaaatgg aacacttttc aaaattaagt gattggaggc aagaatatgg ataaagatta
      121 tatattaaaa gtgaaagggc tgtatcatca atttttacta ggaaataata aaacgttgca
      181 agtgctgaaa aatgtttctc tttctgcttc gagaggagaa tttataagta ttctaggaat
      241 tagtggttct ggaaagtcaa ctttattaaa atgtatttct agtttgcttg aaccaacaag
      301 tggggaagta attttaaatg gaatcaaccc ctataaaatc agaaatgcaa aattgtcaag
      361 tataagacgt aacgaagtat cttttatatt tcaagcatac aatttaatac cttccctgcc
      421 ggtaatagaa aatatagcac ttcctttgcg attatcacaa aaaaaattaa ctattaaaaa
      481 tgtagaaaac ttactcaaaa gaatgaagtt taatgctggc ttaaacgatt ttgttggaac
      541 tctgtctggt ggagaacaac agaaggttgc tatagctaga gcggttattg ctgatagtga
      601 tataatattt gctgatgagc caactggggc tttagacagc gtttctcgtg aagtaatttt
      661 tgaattattg agagagttag taggggcggg taagtgtgta attatggtaa cgcacgatat
      721 agaattggcc tcgaaaactg atcgtgcatt aatattgaaa gatggaaaaa ttttcaaaga
      781 acttcataga cctagcgggg aagagttgta taaaatctta gaggtacaat caactacgga
      841 ggaatagaga tgctcagatt agtttactat caatttttac ataataagaa acaatggtta
      901 ggcgtttcac cagtaatttt tgtttcgagt ttagttatgg gattggctgt taatggggta
      961 attaatgttg agaataattc gcaagtattt gtcggacttc cagatcctaa accaattttt
     1021 atgtttccga tagtattcgg aggagtaaca ttattctttg tgctctctaa cataataaat
     1081 atgttggttg aaatttttag agatgattac gaacttctgg aggtgttggg agcaagtctc
     1141 cttcaactat catttcttgt ggggggacag atttttatca tttcctcgat tattagtttt
     1201 attgcatatc tatgctctat atttgttacg tcaaattatt attatttttt acaatacttt
     1261 ttcggggaaa atatattacc tgatatccaa tttcaaacga gtgctgttgg atgtatcatt
     1321 acagtagtgt tgatttcatt tttagccttt ctaagtggtt gcttttatac gttcaagaag
     1381 attagaaata ggaagagttc taaaataagg catgttcttt caatagtaaa aagaatactg
     1441 ctattggctg gttttagtgt tatctggttg ctttctttgc aacaaatttt ccaagatagc
     1501 acaattttag cgaaggccca gataatattc aatattgtaa tcttagatat tgtgattatt
     1561 tatcaattat ctccttttat acagtcatgt tttatcaaac tactttctat aattatattt
     1621 agaaataatt ttatgttcat tgtttcgaag tggaatttac tatatcgtaa gccttatata
     1681 aaatctatca gtgctgcaat tacaggagct atattactaa tttctagttt tcaaatgatt
     1741 tctcagaata tactatctca atttcaagat gacagtgatt tagagctaaa agtggcattt
     1801 attgtctatg taggagcacc aattttgata gtacttgcaa atattatttc aattgcattt
     1861 ttgtcatcgc atcaagaaag gattgagatt cagcaatttg aaattttagg aacttctaat
     1921 taccagatgg ttaagattaa agttggtgag gctatatttt tgacatttgt tacttcatta
     1981 attgcatttt tact
//
LOCUS       DAVLTT010000119         1890 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVLTT010000119 DAVLTT010000000
VERSION     DAVLTT010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1890
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.119"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            109..1740
                     /locus_tag="VYN15_002086"
     CDS             109..1740
                     /locus_tag="VYN15_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV1453330.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGIGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNTTNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIGLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
BASE COUNT          548 a          398 c          367 g          577 t
ORIGIN      
        1 aattataatt ttcttttaca aacttgacat taacacttgt tagatttact tttatccttt
       61 aaaatagaat aggagatatt ccgcgattat ttttcggagg aaaaagaaat gtccattaat
      121 tggcaggaaa ttttatttca ctttttaggt ggtctggggc tattcttata tagcatcaag
      181 accatgggag acggtttaca acaagctgct ggagatcgcc ttcgttttta cattgacaaa
      241 tatactagta atcctttctt tggagttctg gttggtattg ggatgactgc tctaattcag
      301 tctagttctg gtgtaacagt tatcacagtc ggcctggtca gtgccggtct cttaacctta
      361 cgtcaggcta tcgggattgt catgggtgct aatattggga caactgtcac atcctttctc
      421 atcggtttta aattaggtaa ctatgcccta cctatgctct ttatcggtgc cgtctgtctc
      481 ttttttacaa aaaatcggac agtcaataat atcggacgca tcctctttgg tatcggtggt
      541 atcttttttg ccctcaatct catgagcggc gcaatggctc cactcaagga tttacaggtc
      601 tttaaggact atatgattga gctaagtaag aatcctgttt tgggtgtctt tgtcggtact
      661 ggcttgacct tgctaattca agcttcttcg gctaccattg ggattttaca aaacctctac
      721 gccggcaatc taattgacct acagggagct ttgccagttc tatttggtga caatatcggg
      781 acaaccatta cagccatcat tgcctcttta ggggctaata ttgcagctaa acgggtagca
      841 ggagctcatg ttgccttcaa cgttatcgga acagtcgtct gcgttatttt tctagttcct
      901 tttactgtcc tgattcattg gtttgaagct acgctaaatc tagcaccgga aatgaccatc
      961 gcctttgctc acggaacctt taatactacc aacaccattg tccaatttcc atttatcgga
     1021 gctctggctt actttgtaac caagattatt cctggagagg acgaggttgt caaatacgaa
     1081 cccttatatc ttgatgaaca tttcatcaaa caggccccat ctatcgctct aggaaatgct
     1141 aagaaagagc tcttgcactt aggaaactac gctgctaaag cctttgacct ttcctataag
     1201 tacatcattg gcttggatga aaaagttgct gaaaaagggc ataaaaccga agaagcaatt
     1261 aacaccatcg atgagcaatt aacacgttat ctcattgccc tttcaagcga agctctcagc
     1321 caaaaagaaa gtgaagtgct taccaatatc cttgattcct cccgtgattt ggaacggatt
     1381 ggagaccaca cggaggctct actcaatctg actgactatc ttcaacggaa aaatgttgaa
     1441 ttttctgatg ccgccttgaa agaattagag gaagtttacc gccaaactag tgactttatc
     1501 aaagatgctc tggatagtgt ggaaaacaat gatattgaaa aagcacgcag tcttgtagaa
     1561 cgtcatgaag caatcaataa gatagaacgt gttctcagaa aaacccacat caaacgcctc
     1621 aacaaaggcg aatgttcaac acaagctggg gtcaacttta tcgacatcat ctcacactac
     1681 actcgtgtat cagaccacgc tatgaacctt gctgaaaagg tttttgcaga acaaatctaa
     1741 gaaccaagaa gctatccatc ataattggat ggcttcttac tttttcctaa gcaagactag
     1801 gctgaatgaa actgaaagag tattctgcag atatatagta tattgaaact agaatagtac
     1861 acctctattt ctaaaacatt cttagaaatc
//
LOCUS       DAVLTT010000120         1785 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVLTT010000120 DAVLTT010000000
VERSION     DAVLTT010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1785
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.120"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..239
                     /locus_tag="VYN15_002087"
     CDS             <1..239
                     /locus_tag="VYN15_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HEV1453331.1"
                     /translation="KHLAGGDFQTLTIKRFRHLFLHVVGKCVRTGRKQLLKLSSLYAY
                     SELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
     gene            complement(498..878)
                     /locus_tag="VYN15_002088"
     CDS             complement(498..878)
                     /locus_tag="VYN15_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV1453332.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            complement(1300..>1785)
                     /locus_tag="VYN15_002089"
     CDS             complement(1300..>1785)
                     /locus_tag="VYN15_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1453333.1"
                     /translation="YTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADT
                     NQTEKPSEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESEEPQVETEKV
                     EEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALLKES
                     K"
BASE COUNT          512 a          359 c          320 g          594 t
ORIGIN      
        1 tcaaacatct agctggaggt gacttccaaa ctttaacaat caaacgcttc cgccatcttt
       61 ttcttcacgt ggtgggaaaa tgtgttcgaa caggacgcaa gcagctcctc aaattgtcta
      121 gtctctatgc ctattccgaa ttgttttcag cactttattc taggattaga aaagtcaacc
      181 tgaatcttcc tgttccttat gaaccaccta gaagaaaagc gtcgttaatg atgcattaaa
      241 gaacagtcga gatgaaaaaa tcgtgtgacg caccaaggga ggagtctgcc cttttgagga
      301 aatctagcga ggaaaaacga tactggaaca gcagaaagta aaactgacct catgaggagg
      361 aagaaagtgg ctcatgaggt caggggtttt gtaagttaca tctagttgag agaggtatga
      421 atgatttggg tttacttaac attttatagt tgagataatc aatagcttac ctataaaaag
      481 agttatagta aaattcctta tttattgatt tcaagctccg ctaactgtgt ttgaataact
      541 gacagttctg caccagcctg aagaagagca gctgcattat aggcaccttc tacaattgga
      601 accctgttga tgatgatact tttatcactg aaatcagtca ccatttttaa gttcatttta
      661 gcagaaccta ggtcaaaaaa ggcaagtaaa gtatctgctg gattttcgga aacaacccta
      721 tctacttgat caaaactcgt tccaattcct ccgccctcgg ttcctcctac ataagtaatc
      781 ggaacatctt tagctacttt actaatcagt tcaacaacac cttctgcaat gtgtttggaa
      841 tgtgaaacga taacaagacc aataccaata ctttccatca aaccacccca gtttctaaaa
      901 tagcagtaaa gagtaatcct gatgagaatg atccaggatc aatatgtcca agaaaccaca
      961 tgctcctaag acaagagcta acagactggc catcaataat agtattgttc tttttttcat
     1021 cattactcct taactagtgt ttaactgatc aattagccag taaatagttt atctttattt
     1081 acactatctg ttaagatata gtaaaatgaa ataagaacag gacagtcaaa tcgatttcta
     1141 acaatgtttt agaagtagag gtatactatt ctagtttcaa tctactatat tttgcacatt
     1201 ttcatgaaaa aaatgagaac tagaactcac attctgctct catttttcgt tttcccgttc
     1261 tcctatcctg tttttaggag ttagaaaatg ctgctacctt tacttactct cctttaataa
     1321 agccaatagt ttttcagctt ctgccataat agtattgttg tcctgggtgc caaatagtaa
     1381 attatttttt aatcctgtga gagtctcttt ggcattggac ttgataattg gatcctggat
     1441 ttttccaagt aaatcttcag cctctctcag tttttcttca accttttcag tctcgacctg
     1501 aggttcttct gattcctctg gtgattcttc ttctggttcc tctgttggtt ttggagactc
     1561 tggtttctcg ctttgcggtt tctcttctcg aggggtttct tcctcaggtt tttctgtctg
     1621 aggtttctcc tcgcttggtt tttccgtttg attggtatca gcttgaccat ttttgtttct
     1681 ttgaacatgg tcactagcgt taccaaaacc attatctgaa tgcggacgtt cgtttggatg
     1741 ttcgacatag tacttgacag tcgccaaaag atcctcaaga gtata
//
LOCUS       DAVLTT010000121         1769 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVLTT010000121 DAVLTT010000000
VERSION     DAVLTT010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1769
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.121"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(88..525)
                     /locus_tag="VYN15_002090"
     CDS             complement(88..525)
                     /locus_tag="VYN15_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1453334.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            complement(566..1573)
                     /locus_tag="VYN15_002091"
     CDS             complement(566..1573)
                     /locus_tag="VYN15_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000231692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1453335.1"
                     /translation="MVFNPLYTFWIDYVKFFYRPYYSCRKIFKEEDSINHRKASYINT
                     QDNNYNKHIKDYFSMVDNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILL
                     KKIFDVGLRKGYYSSNPAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFT
                     VLFFTGLRLGEALALTWQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAGTRRIVINK
                     KLSQELQDWEKRQKHLLEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSILKK
                     IRIHDFRHSHASLLINQGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDL
                     L"
BASE COUNT          509 a          274 c          280 g          706 t
ORIGIN      
        1 cgagaccgac cgccagtata gtaataaaga caaagtttat aagccttgtc ttttgttttc
       61 tctttataaa attttatagt ttagttacta actttttttc tttgctctta aaaatctaat
      121 agcagaactg tatttcttat ttctctctaa gtctttttca gtaattaatg gtagtcttgt
      181 taaatctgaa ttatgccgta aatccgccaa ctttacaact ctagcgagtt catttttctt
      241 tactagattg agataagatt gataatcttg tccttttttc tttgtgagta tatcaacggc
      301 ttctataatg ttttttgaaa aaccttcctt ttttaggtct agtagggtta gtgaagtatc
      361 ttcaattaca tcatgtagat aggcgacagc tttctcttca tcagttgcga caaaactagc
      421 tactgtttca gggtgtttaa tgtagtcaat tcctgctcta tcaatttgtc caaagtgtgc
      481 ttttttagct acttcatgtg cttttattac ttgtgatgta tccatgattt aattataaac
      541 tttccattta taaaactcaa ttactttata gtaaatcatc tagtttatca gctaaatcct
      601 tttgcttact tgggtacaag tgagagtagg tatcaatcgt ggttgttata gaagcatgtc
      661 ctagtcgctc ttttacaact agataatctt ccccttggtt aatcagcagg gaagcgtgtg
      721 agtgcctaaa atcgtgtatg cgtatctttt ttagtatgct atcacgttca atgattttct
      781 tgtactgctt ttcaatagca ttttttgtaa ttgtgatagg actattttga aacacttgta
      841 atgttaggct attgttggta aattgctcta atagatgttt ttgtcgcttt tcccaatctt
      901 gtaattcttg gcttaatttt ttattgataa caattcttct tgttcctgct ttagtttttg
      961 ttgtgctgat atgagttact cctttattaa catagacaga cttcgtgata tgaattgtat
     1021 tacttgaaaa gtcgatgtct tgccatgtta gggcaagagc ttccccaagt cttaatcctg
     1081 taaagaatag aacagtaaag agtagtttga tattgtattc ttcgggttca aatagtgtca
     1141 aaaacttctg aaattctttg actgtccaaa attgcatttt tgttttttca attggcaact
     1201 tttttattaa ttttgctgga ttggaggagt aatagccttt tcgcaaacca acatcaaaaa
     1261 tttttttgag taaaatcatg attttgttaa tagtatttgt gcttaacggt ttatcagaat
     1321 ttttagctac tttttgccta agatgttctc taaattggta gatgtcttca taggttagtt
     1381 ttccgacatt atcgaccata gaaaaataat ctttgatgtg tttgttgtaa ttattatctt
     1441 gtgtattgat atagcttgct tttcgatgat ttatactatc ttcttcctta aaaatttttc
     1501 tacaagaata ataaggcctg taaaaaaact tgacataatc aatccaaaag gtataaaggg
     1561 gattgaaaac caagtattta tcaataagag gcccactaac aattcagttc ctattctact
     1621 aagaaaaagt ctacgagaag taataacata gggattaact tttactttca cagatttgct
     1681 cagtttcagt attttcatct tcattcctct cagaaattaa tgtatctata caaccaatta
     1741 aaaagataaa tggattttaa taaggtcag
//
LOCUS       DAVLTT010000122         1686 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVLTT010000122 DAVLTT010000000
VERSION     DAVLTT010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1686
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.122"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            45..836
                     /locus_tag="VYN15_002092"
     CDS             45..836
                     /locus_tag="VYN15_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1453336.1"
                     /translation="MNFALNKGEIVGQVGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     VGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLSVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLSITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            852..1580
                     /locus_tag="VYN15_002093"
     CDS             852..1580
                     /locus_tag="VYN15_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1453337.1"
                     /translation="MKLNKFNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAILGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
BASE COUNT          559 a          220 c          277 g          630 t
ORIGIN      
        1 taaatgtaag taagcattat ggtcattcaa tcattctcaa agacataaat tttgcactta
       61 acaagggtga aattgttggt caagtaggga gaaatggagt tggtaagagt acgttgatga
      121 aaattcttgt tcagaataat caaccgactt caggtaatat tataagcagt gataatgttg
      181 ggtatttaat cgaagaacca aaattatttt tatctaaaac aggtttagag aatttaaaat
      241 atttgtcaaa tttatatggt gttgactaca atcaagaaag atttagaagt ttgatccaag
      301 agttagattt gactcagtct attaataaaa aagtaaagac ctattctttg ggtacaaaac
      361 aaaaattagc tttgcttcta actctcgtta cggaacctga tatattgatt ttagatgaac
      421 cgactaatgg tttagatatt gaatcatcac aaatagtttt atcggttcta aaaaatttag
      481 ctttacatga aaatgtggga attttaatat cgagtcataa attagaagat attgaggaaa
      541 tttgtgagag ggttcttttc ttggagaacg ggcttttgac atttcaaaaa gtaggaaaag
      601 atagtcataa tttcttgttt gagatagctt tttcatcagc tacagataga gacattttca
      661 ttaccaaaca agaatttggg gatattgttc aggaagaggg actgagcatt actatgtctg
      721 ggaatattca aagtagtgag ctttttaaat tttttaacga aaactctatt aaagtagttg
      781 attttgaaac taaaaaagag acgcttaaag atatttatct aaatcgttca aaataaagga
      841 aggttataat catgaaatta aataaattta attttcttaa ggaaaatata agaaatttat
      901 attcatcagg cgtaatatat ctcagtttgc ttatctcgtt tataccgccg atattgctta
      961 cattctttat tctaaagact caagggacat cgcttggtat taagcatatt tcaaactttt
     1021 atgctatact cggtatgtta atggctgtta tacatgctaa tcgagtcatt agtagagatt
     1081 tttcccacaa tacggtaagt ttgttttata atcaacagaa gaatcggatg atttacgtct
     1141 tgtctaattt tctatatgcc atctcagttt ccattattta tgctttgaat ggcattgtgt
     1201 tactagtcat agtaagtaaa ttgggtattc caggtgattt aggattagat tttatagtag
     1261 ctattgtagt caatacaatt ttgttagtcc tgttttattt tctattatct tacattttct
     1321 atttatacaa attgaaaagt ggcttggtat ttggtatttt agtagcttta ctactcttta
     1381 tccctaatat attaaatacg atgatgatga atactagtaa tgatttgttt atcaaagcaa
     1441 ttgaacttct tcctttttat tctttacctg tatttgtggc ttcaaatacg atgtctatta
     1501 gtcagtatct tgtgctaatc actacaatca ttttattgta ctttttcact ctcaagaaaa
     1561 gcaagaagta ttcattttag tttcatttag tattattttg catacctaaa atacaataaa
     1621 aaaatcagtc atcttggtat gctcctgctt tcactattca acacgttttt gacttatact
     1681 aggctc
//
LOCUS       DAVLTT010000123         1678 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVLTT010000123 DAVLTT010000000
VERSION     DAVLTT010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1678
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.123"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            338..>1678
                     /locus_tag="VYN15_002094"
     CDS             join(338..779,779..>1678)
                     /locus_tag="VYN15_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1453338.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKEIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTK"
BASE COUNT          578 a          264 c          374 g          462 t
ORIGIN      
        1 cgttgcggta actggagtgc ttttagttgg gaaaattgtt aattcattta aattgtaaac
       61 tttagggatt ctctgaagtt atggatgtcg ttccaatatg tgtacgttgg aatgttagtg
      121 cttatatggg gggaacagaa tcctctcttg attgaagaca agttagccat taggctggtt
      181 tgtctctttg tcaactgtag tgggttgata taatagtatt agtgagtggg ataaaagttt
      241 catttagttt attcagtaca aatttaacgg gtcaagattt attgaactgc accccaatag
      301 ttagacagaa aaaatctaac ttttggggtg ttttattatg aaattgagtt atgaagataa
      361 agttcagatc tatgaactaa gaaagcaagg acaaagcttc aaacagcttt caaaaagatt
      421 tggtgtggat gtttctggtc taaagtacat ggtgaaatta attgaccgtt atggcataga
      481 aatcgttaaa aaagggaaga atcgtcacta ttcttctaaa ttgaaacaag aaatgatgga
      541 taaagcctta ctggaaggtt gttcacaaag aagtattagt cttgattatg ccctcccaaa
      601 ccaaggaatg ctttcatttt ggccggcaca atacaagaaa aacgggtata ctattgttga
      661 gaaaacaaga gggagaccag ctaaaatggg acgtaaacgg aagaagactt gggaagaaat
      721 gacagaacta gaacgactcc aggaggagaa tgaacgctta cggactgagg tggcctacct
      781 aaaaaagtta aaagagttag aggaaaggga cgaagcccta gagcgagaaa ggcagagaca
      841 gttagagaaa tggtttcagg aggatttcga ctagattttc ttcttgaaac agcacgttta
      901 gctcgctcga cttactatta tcagttgaaa caactggatg gggttgataa agataaagag
      961 attaaaaccg aaattcaggg cattgataat gaacataaag gcaactatgg ctatcgtcga
     1021 atccatttag aactaaggaa tcgtggtttt gtggtcaatc ataagaaagt tcaacggttg
     1081 atgagaattc ttggtttaac ggctcgaatt cgccgtaaac ggaagtattc ttcctaccaa
     1141 ggagagattg gcaagaaagc agagaatctc attcaacgcc agttcgaagc atcgaggcca
     1201 atggaaaagt gctatacaga tgtgacagag tttgccattc caaatagcac acagaaactc
     1261 tatttatcac cagttttaga tggttttaac agtgaaatca ttgcttatca tctttctact
     1321 tcgccaaact tagaacaagt gaagagtatg ttagaacagg cctttacaga gaaatactat
     1381 gagaatacga ttctccatag tgaccaaggc tggcaatacc aacacgattc ttatcatcgg
     1441 ttcctagaga gtaaggaaat tcaagcatcc atgtcacgca agggcaacag cccagacaac
     1501 ggcatgatgg aatctttctt tggcatttta aaatccgaaa tgttttatgg ctatgagaag
     1561 aactttagat ctttagaaaa ccttgaacaa gctattgtgg actacattga ttactacaac
     1621 aacaaacgaa ttaaggtaaa actaaaagga cttagttctg tgcagtacag aactaaat
//
LOCUS       DAVLTT010000124         1551 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVLTT010000124 DAVLTT010000000
VERSION     DAVLTT010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1551
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.124"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..791
                     /locus_tag="VYN15_002095"
     CDS             <1..791
                     /locus_tag="VYN15_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1453339.1"
                     /translation="FLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWTYS
                     MGDAFICVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVVGVQDFKKEFCISNNKK
                     IICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICHLKCRDNF
                     RLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLSEIIEHRV
                     DGFLFEKEDVEGVCTCANFLLNDSEYLKYIGENSKSKIRKHESI"
     gene            815..>1551
                     /locus_tag="VYN15_002096"
     CDS             815..>1551
                     /locus_tag="VYN15_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1453340.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLINKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLVQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLS"
BASE COUNT          580 a          141 c          310 g          520 t
ORIGIN      
        1 attttttata tatgttaaaa aaacttgaca agaatggatt tggaaaggtt aagacagtga
       61 taacatgcca tggatgggtt gaatataact taaaaaagaa attcttgact tattttgatt
      121 tttggacata ttctatggga gatgctttta tttgtgtatc tgaaactatg aaaaaaagat
      181 tggagagtat aataaaaaat aagaagatag ttgcaataaa taacggaatt aatgtatcaa
      241 atagcgattt agatgtagta ggtgttcaag actttaaaaa agaattttgt atttcaaata
      301 acaaaaaaat catttgttat gttggaaggt tggatccaga aaaaaggccg gatagattcc
      361 ttgaatttgc agaaaaatta tttttagtca gagaagatgt gatttttatt atggctggaa
      421 atggtagtat gtgggctgct ttgaaagaaa aaatttgcca tttgaaatgt agagataatt
      481 tcaggttact tggtgaaatc tatccagcta ctatagttta ccaaatatcg gatttattgt
      541 atattccttc tgatacagaa ggaataccta tgtgtgtttt agagtcaatg tcacaaggaa
      601 ctccggtttt agctagtaat gttggcgggt taagtgaaat tattgaacat agggttgatg
      661 gatttttatt tgagaaggaa gatgttgagg gagtgtgtac ttgtgctaat tttttactca
      721 atgattctga gtatttgaaa tatataggtg agaatagtaa atcaaaaata agaaaacatg
      781 agagtatatg atgaattatt agagaagagt agtcatggat aggaatatag atcaagaatt
      841 agtaagtatt ataataccaa cacataatag gtatgaatct ctgattagag ctgtgaaaag
      901 ttgtttacat caaagttata aaaatatcga agttataatt attgatgata attatagtaa
      961 tgtaaattta ataaataaaa ttatccatca atttggctat accaatcata gaattaagtt
     1021 aattttaagt aatgaagatt taggtgcaac taatgccaga aacataggta tcaaaaattc
     1081 tagaggtaag tatatatcat ttttagacga tgatgatgaa tatatgccag atcgaatttt
     1141 aaagttgatg gcttgtttta aaaagagtag aatgaagaat ttagctttag tttatagtta
     1201 tggaataata atttatccaa atggtacacg agaagaggag aagaccgatt ttgttggaaa
     1261 tcccttgttt gttcaaatgg ttcacaatat agcaggtacg tcattttggt tgtgtaaaaa
     1321 agaggtgcta gaattaatta atggttttga gaaaatagat tcacatcagg acggtgttgt
     1381 tttattaaaa ctacttgttc aaggatacca aattgatata gtgcgagaat tcttggtgaa
     1441 ttactacgct cacagtaaag aaaacggtat cactggagtg acacaaaaaa caattaatgc
     1501 agatgaagaa tattataatt actgtaggaa atattttaat ttattgagtt t
//
LOCUS       DAVLTT010000125         1550 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVLTT010000125 DAVLTT010000000
VERSION     DAVLTT010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.125"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..239
                     /locus_tag="VYN15_002097"
     CDS             <1..239
                     /locus_tag="VYN15_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HEV1453341.1"
                     /translation="KHLAGGDFQTLTIKRFRHLFLHVVGKCVRTGRKQLLKLSSLYAY
                     SELFSALYSRIRKVNLNLPVPYEPPGRKASLMMH"
     gene            complement(402..1037)
                     /locus_tag="VYN15_002098"
     CDS             complement(402..1037)
                     /locus_tag="VYN15_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1453342.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGDSLSQIIHTSLN"
     gene            complement(1106..1405)
                     /locus_tag="VYN15_002099"
     CDS             complement(1106..1405)
                     /locus_tag="VYN15_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1453343.1"
                     /translation="MKTKKHRLLALVLISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWDGHSDKGEAPAGKTSYAWIWTKWGEQVAFYYDYD"
BASE COUNT          498 a          304 c          283 g          465 t
ORIGIN      
        1 tcaaacatct agctggaggt gacttccaaa ctttaacaat caaacgcttc cgccatcttt
       61 ttcttcacgt ggtgggaaaa tgtgttcgaa caggacgcaa gcagctcctc aaattgtcta
      121 gtctctatgc ctattccgaa ttgttttcag cactttattc taggattaga aaagtcaacc
      181 tgaatcttcc tgttccttat gaaccacctg gaagaaaagc gtcgttaatg atgcattaaa
      241 gaacagtcga gatgaaaaaa tcgtgtgacg caccaaggga ggagtctgcc cttttgagga
      301 aatctagcga ggaaaaacga tactggaaca gcagaaagta aaactgacct catgaggagg
      361 aagaaagtgg ctcatgaggt caggggtttt gtaagttaca tctagttgag agaggtatga
      421 atgatttggg ataaagaatc ccccatgatg gataagagag tctgaccaga aaagagtttt
      481 atacctgctg ctctcatttc cttaatccga gtgataatca ctaaagcaaa gaaagataag
      541 ccaaatattg ctaaactaat taaaataagg ggatttagta atattcgaaa agcaagaaaa
      601 tagggcggta tctttcggtc agcacttgct ttataaccca aatctcctaa tttatcggca
      661 agcttttctt tcgtcaagga gcctgacaaa aggagataac tatttagcgg atcactacgt
      721 tcacgacttt cttggctagc ttcttggaat tcttttggta aagttccctg accataagtt
      781 gcataagtaa agtgagtcgt cccatcctta ctcggctcta caattcttct agctattaaa
      841 ctctgttctg agtttgcaaa attctccaat tcctgttcaa atacctcacg cgtcggttcc
      901 tgagtatctt ttttgacacg aagtaaagaa acggaatcat agcttgcata taaatattgt
      961 ggcgcacgta agacaataat ccaagcaagg aagaagctga gaaaaaaagt tgataataat
     1021 atgaatagtt tcttcatagt agactccttg taagaaattc cccctgtaat ttcttacaag
     1081 gggaattatc taagaaaact aaatattagt catagtcata gtaaaatgct acttgttctc
     1141 cccatttagt ccaaatccat gcgtaggagg tttttccagc aggagcttct cctttatcag
     1201 aatgaccatc ccatctgctc acgatggatg aataatgata ttttttacca tgatagtaat
     1261 ttgaaaaagc ccaaccacct cctgaacctt ctccatatgt ccatactcct ccatctggat
     1321 attgtacagc agctgatgca gctcccaata atgtaaaact tgaaataaga actagagcaa
     1381 gtaatctatg ttttttcgtt ttcattttat tttttctttc aaaaaaagca caccttgagc
     1441 aacaatgcaa caaaataaac cctcctctct cttttgttga aaccgctttc ttatgtgata
     1501 agaataacat ttttattatt tgttgtcaag gaaaaaatcg aattttttag
//
LOCUS       DAVLTT010000126         1542 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVLTT010000126 DAVLTT010000000
VERSION     DAVLTT010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1542
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.126"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            94..390
                     /locus_tag="VYN15_002100"
     CDS             94..390
                     /locus_tag="VYN15_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEV1453344.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            397..1533
                     /locus_tag="VYN15_002101"
     CDS             397..1533
                     /locus_tag="VYN15_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453345.1"
                     /translation="MKILSKKECESILGYLNFIGITLLFFVIISLSIYFKSYLPFQGK
                     LFLLFLVVDYATLNRYNMKLPIQSKKINTFYIRKNYIFLYLLAIVKKYYSFQILQSFI
                     YLFILYFLDIIGYFYLSITLCLIAIQIISLILPSLFSIISKLFLFLSIGLLSIEQGQV
                     VIYVILLNYFILVMGILDNHASNFYFKSSRMSQKRFRSSLFILLRFCWLNKGLTFSFI
                     LISILLSYLFWYMMTMLSIDDTKIPILFLYTSIYITLMEAIIGNHKSSIGVDLALLQL
                     SALNHSKMNFFFKNAQLMMLTHLISFLQFSLLLCLIPVTSYSNDIKSILLNLLLIPFN
                     YFIAYVYYKKALFLIKGTVSLLRWSFLVLYCFLIIFVILVGGIR"
BASE COUNT          489 a          185 c          235 g          633 t
ORIGIN      
        1 atatagacga acatttgaag agagttagga atacaacatg tgcgaattaa ctctcaataa
       61 aacatacata atatacaaaa ggagtacact aaaatgaaat ctaaaagaat ggaatttcat
      121 aataaatttc ttattgtttc agcaatgtta gcagtcatta gttggttaag cttaggtgtt
      181 gtttcttttc ctatgttggc tgggacatta ggaatttcga caaaagctgc tgctactgta
      241 gtcaatttga ttagtgctta tagtacagtt acagcagtaa tttcaattgt aggtgcaatc
      301 acaggagtag gttctattgg ttcgggtatt gcagcaacag ttctttatat attgaaaaag
      361 aaaggtgctg ctaaagcagc tctatggtag aactagatga aaatactttc taaaaaagaa
      421 tgtgaaagta ttttaggtta tcttaatttt attgggataa cccttttgtt ttttgttatc
      481 ataagtttgt caatctattt taaaagctat cttccttttc aagggaaatt atttttactt
      541 tttttggtag tagattacgc tactttgaat cgttataata tgaaactgcc tatccaaagt
      601 aaaaaaataa atactttcta tataaggaaa aactatattt ttctctatct tcttgccatt
      661 gtcaagaaat attattcttt ccaaatttta caatcattca tttatttatt tattttgtat
      721 tttctagata ttattggata tttttattta tccattactc tttgtttgat agctattcaa
      781 attatttctt taattctacc tagtttgttt tcaattataa gtaaattgtt cttattttta
      841 tctataggac tattgtctat agaacaagga caagttgtaa tttatgtcat actactcaat
      901 tattttattt tagtcatggg gatattagat aatcatgcga gtaatttcta ttttaaaagc
      961 agtcgaatga gtcaaaaaag atttcgtagc agtctattta tattgcttcg tttttgttgg
     1021 ttaaataaag ggttaacttt ttcttttatt ttgattagta ttcttctttc ctatctattt
     1081 tggtatatga tgacgatgtt atcaattgat gacacaaaaa taccaatatt atttctttat
     1141 acctcaatat atattacatt aatggaggca ataataggga atcataaatc ctcaattggg
     1201 gtagatctag ctttacttca attatctgct cttaatcatt ctaaaatgaa tttctttttt
     1261 aagaatgcac aactaatgat gttgacgcat ttaatctctt tcttacaatt ttcattgttg
     1321 ttatgtttga ttccggtgac aagttatagt aatgatataa aaagtatttt gttgaatttg
     1381 ttattgattc cattcaatta ttttatagcc tatgtctatt ataagaaagc tctattttta
     1441 attaaaggta cagttagttt attgagatgg agttttctgg ttttatattg ttttctgata
     1501 atatttgtaa ttttagtagg gggcattaga tgagaaaaag tg
//
LOCUS       DAVLTT010000127         1539 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVLTT010000127 DAVLTT010000000
VERSION     DAVLTT010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.127"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(1..144)
                     /locus_tag="VYN15_002102"
                     /pseudo
     CDS             complement(1..144)
                     /locus_tag="VYN15_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(493..885)
                     /gene="rpsI"
                     /locus_tag="VYN15_002103"
     CDS             complement(493..885)
                     /gene="rpsI"
                     /locus_tag="VYN15_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV1453346.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(904..1350)
                     /gene="rplM"
                     /locus_tag="VYN15_002104"
     CDS             complement(904..1350)
                     /gene="rplM"
                     /locus_tag="VYN15_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV1453347.1"
                     /translation="MNKTTFMAKPAQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISELI"
BASE COUNT          446 a          293 c          306 g          494 t
ORIGIN      
        1 gaggtgcttt ttgatatgag cccatgtttt ctcaatagga ttgtactcag gtgagtaggg
       61 aggaagaggt aaaagtttat acccaaactc ttcacacaag agttctagct tccccattct
      121 atggaatctt gcattatcca taatatagta gattgaaagt agaatagtac acctctactt
      181 ctaaaacatt gttagaattc gatttgacta tcctcgattt gtcctattct tatttcatat
      241 tactataaaa ataaggtaaa cttttcaaaa aagcacgaaa aaagcaccca taaggtaaac
      301 ttttgagtgc tttgaaacat tgatataatc gtattgatta acgttttgag gcaactgacc
      361 ttgtcaggtt gcagccacat ttgtaagcga ctaaagtcgc aacaactgtg tcaattgcac
      421 caatttaata agaaagtata aaaaaagaac accccgaaag gtgctctgta taagtatagt
      481 aattctttcg aattaacgtt tactaaattg tgatgcttta cgagctttct taagacctgg
      541 tttcttacgt tcaactttac gtgagtcacg tgtaagaagt cctgcgcgtt tcaatgaatc
      601 gcggaagtct gggtctactt gaagaagggc acgagcgata ccgtgacgga tagctcctga
      661 ttgaccagcg tatccaccac ctacaacgtt aacgaaaacg tcgtatgaac ctacagttga
      721 agtaactgcg aatggttggt tgatgacaag acgaaggtca gcgtgtggga tgtactcttc
      781 aacatctttt ttgttaacag tgattttacc agttcctgga acaaggcgaa cgcgtgcaac
      841 agcgttttta cgacgtccag tacctgcata ttgtgcttgt gacatacttt attgttcctt
      901 tccttagata agttctgaaa tgtcaagaac ttctggttgt tgtgcagcat gagtgtgctc
      961 agctccaaca aatactttca acttcatacc ttgagcgcgt ccaagtgtat tgtgtggaag
     1021 cataccttta actgatttct caatcaaacg tactgcattt ttagaacgaa gttcacctgc
     1081 agagatttgt ttcaatccac ctgggtggtt tgagtgagtg tagtagattt tatcagttgc
     1141 ttttttacca gtcaatttaa ctttttcagc attgataaca atcacgaagt cacctgtatc
     1201 agtgtgtggt gtaaatgttg gtttgttttt tccgcgaagt acgctagcaa ctactgcaga
     1261 aagacgtcca agtggtacat cagttgcgtc aactacgtac catttacgtt caacttgggc
     1321 tggtttagcc ataaatgttg ttttgttcat gatttctcct atatatagtt cgatttttgt
     1381 ttacggtgat gggtgttcct tcccatcgaa aagtatttgg aaggttccgg ggcctttcaa
     1441 atggggtaaa caataccgcc tactatcata ccaaatttca cccctaaaag tcaatagata
     1501 tgaaaaatat ttttcggtaa cttctcaaag taactgaaa
//
LOCUS       DAVLTT010000128         1490 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVLTT010000128 DAVLTT010000000
VERSION     DAVLTT010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1490
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.128"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            14..1360
                     /gene="gdhA"
                     /locus_tag="VYN15_002105"
     CDS             14..1360
                     /gene="gdhA"
                     /locus_tag="VYN15_002105"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV1453348.1"
                     /translation="MTSAKEYIQSVFETVKTRNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          452 a          296 c          319 g          423 t
ORIGIN      
        1 aaaggagaac gatatgacat ctgctaaaga atatatccaa agcgtgttcg aaactgtaaa
       61 aactcgtaac gggcacgagg ctgaattcct ccaagctgtt gaagaatttt tcaacacttt
      121 ggaacctgta tttgaaaaac accctgagta tatcgaagaa aatatcttgg cacgtattac
      181 tgagcctgag cgcgtggttt ctttccgtgt tccttgggtt gaccgtgatg gaaaaattca
      241 agtaaaccgt ggttaccgtg ttcaattcaa ctcagctgtt ggaccataca aaggtggact
      301 tcgtttccac ccaactgtaa accaagggat cttgaaattc ctcggatttg aacaaatctt
      361 taaaaatgtc ttaactggac ttcctatcgg tggaggtaaa ggtggatcag acttcgatcc
      421 taaaggtaaa acagatgctg aagtgatgcg cttctgccaa agcttcatga ctgaattgca
      481 aaaacacatc ggaccatcac ttgacgtacc tgctggtgat atcggtgttg gtggacgtga
      541 gattggttac ctttacggtc aatacaaacg tcttaaccaa tttgatgctg gtgtcttgac
      601 tggtaaacct cttggatttg gtggtagctt gattcgtcca gaagcaactg gttacggttt
      661 ggtttactat actgaagaaa tgctcaaagc taacggtaac agctttgctg gtaagaaagt
      721 cgttatttca ggttctggta acgttgctca atatgctctt caaaaagcaa ctgaactcgg
      781 tgcaactgtt atttctgttt ctgactcaaa tggttatgtc atcgatgaaa atggtatcga
      841 cttcgatctt ttggttgatg ttaaagaaaa acgtcgtgct cgtttgactg agtatgcagc
      901 tgaaaaagca actgcaacct accacgaagg tactgtatgg acttacgctg gaaactatga
      961 cattgctctt ccatgtgcca ctcaaaacga aatcaacggt gaagcagcta aacgtttggt
     1021 tgctcaaggc gttatctgtg tatctgaagg tgccaacatg ccgagcgacc ttgatgccat
     1081 caaagtttac aaagaaaatg gtatcttata cggacctgca aaagctgcca acgctggtgg
     1141 tgtagccgtt tcagcccttg aaatgagcca aaacagcctt cgcctctcat ggactcgtga
     1201 agaagttgat gaccgtctca aagacatcat gacaaacatc ttcaacacag ctaaaacaac
     1261 ttcagaaaca tacggtcttg ataaagacta ccttgcagga gctaacattg ctgcctttga
     1321 aaatgtagca aacgctatga ttgcccaagg tattgtttaa gatttatttg cttaatcctc
     1381 aatcactacg attggggatt tttagttgag ttagacagtt gggaaattct aattaaataa
     1441 aataaaaact gaacaaatta attgcggaat tcaaaccaat ttctaacata
//
LOCUS       DAVLTT010000129         1476 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVLTT010000129 DAVLTT010000000
VERSION     DAVLTT010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.129"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(<1..702)
                     /locus_tag="VYN15_002106"
     CDS             complement(<1..702)
                     /locus_tag="VYN15_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453349.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEV"
BASE COUNT          562 a          263 c          183 g          468 t
ORIGIN      
        1 aacctcactc tgattctgaa gcaagtagga gtcaagcaaa ttttcaaaaa tagctaacaa
       61 tatgattggt gtaaggtttt tgtattcaca tgtcaagtat tccgagtatc gtgcagatga
      121 tatttctttt atataacttt ttgaaagcaa gattttttca aattcatcat ctattattaa
      181 tcttctattt ccaatccaag cagtattacc acccaaataa gattgtacaa atagcaatat
      241 gtaagagaac atgaacgtaa atactgaaag aggtagaatt ctatgcgtaa aaaaatagac
      301 gataatggta gccaggagta aagctatctc tcgtgacaat cgaattcttt tcagcatctt
      361 ttttaacagt ccgtaaggtt gtccttggca atattcttga actaaattaa tcggaatgac
      421 atctctcacc atttctggaa agtagagtaa gtttataggt tgaaatctcc agctcccatc
      481 ataagtaaat ggatatagaa ccaaatactt aaaagatttt tttcttataa acttaattat
      541 cacaatatga atgactgttg caatgaagta tattaaatat aaaagtaaaa ccgccatcaa
      601 tatacttaca aaaatcccct tggaatcaat caatggaaaa taaaatattg caactagaag
      661 cgaataaagt cccgctaata aatatttctg atcatctttc attcaaaaca ccatattatt
      721 tactaagaat acatcagtac aatagagcaa ttctgtaagt caatatttga taaagcaaag
      781 ctttaaaccc ttccccagac gtcagctttt attcaaccca ctacagttga caaggagccc
      841 aaattattga taaaaacttt agtcatcatc gtctctataa aaatattttc tatacactct
      901 tgataatacc aaaattaatg ccaatatcat accaagagct ataataataa aataacaaaa
      961 aatgaatttc accaattcct gcaaaaaaat gtttcatagc tatagtttta cgcccataaa
     1021 tatccatcaa atttaccgtc tacgatatct aaaccatatg caatggctcc tcctaatgag
     1081 aaaacttcag caacagtagc cgcaatatta agagcattag taatagttgc catactaact
     1141 ccaccaatat atcttgttat agcacttagt tacctagata agatatcctt tagcttgctt
     1201 ccaaaattta agtctgcacc tataatatga gttcatatta gtactgctaa atcctatcta
     1261 tagtaatgta aaacacctaa ataaagtcat ctctccaatt cattcaagaa atgaagaaag
     1321 gcaaaaaatc tttaaaataa gaaaaatgca tattatcagg tgttcaaaaa tattgatgat
     1381 atacgttata tagatagaaa gatttactca atctcacttt caaattgagt tttttcccaa
     1441 cctcgttttt aatttatatc ttcaataaaa tctaat
//
LOCUS       DAVLTT010000130         1364 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVLTT010000130 DAVLTT010000000
VERSION     DAVLTT010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.130"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..394
                     /locus_tag="VYN15_002107"
     CDS             <1..394
                     /locus_tag="VYN15_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453350.1"
                     /translation="LDAGTYSNLIFEVTKKNILSGGLAVCIEAILDRIHISQKPKKVF
                     VKYVGGENFKIDDFYNILTLIRKEKLKNHFVKEEVSSLAIAKAKRRAYIQKYDLFIAI
                     GEREKNSHEFMIEELKTGLRRILILNGG"
     gene            384..1334
                     /locus_tag="VYN15_002108"
     CDS             384..1334
                     /locus_tag="VYN15_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453351.1"
                     /translation="MEDNQVRRKLYYGISSAAGWSWGVSFLVTYTLIHEKGVIPFAVW
                     AFFNSLAIPIFGVLFKKLSRLKEIMVNNLWLVYFMAIVQCFSIIINLQAMFQMGTLIG
                     LSSSMSTLISLFAGGIFIISVIKNGYKTVLYSNVIQWLISILAIIILIFIGFSGNKEV
                     SLRAYTDVNSIYWSLYAGILLLFSPFVDMQGWVRAIEIKKNRDFEAFGLSGIFFAIYM
                     LLILVLSQFELSVHMGIILLFLVIMISTSTIQPNAHALNVNFKYGWIGALIACLLWPL
                     LSRFGILTLWTYLASFRAIVVALVFMYMGYEKIRELVIFK"
BASE COUNT          446 a          153 c          260 g          505 t
ORIGIN      
        1 tttagatgct ggaacttact ctaatttaat atttgaagta actaaaaaga acattctcag
       61 tggtggtttg gcggtctgta tagaagctat tttagataga attcatattt cacaaaaacc
      121 taaaaaagtt tttgtgaaat atgttggtgg agagaatttc aaaatcgatg atttttataa
      181 tattttgact ctcatccgaa aggaaaaatt aaaaaatcat tttgttaaag aagaagttag
      241 ttcgttggct atagctaaag ctaagaggag ggcctacatt cagaaatacg atttatttat
      301 agctattggt gaaagggaaa aaaacagtca tgaatttatg attgaagaat taaaaacagg
      361 attaagaaga atattaatat taaatggagg ataatcaagt gcgaaggaaa ttatattacg
      421 gaatcagttc agcggctgga tggtcttggg gagtttcttt tttagtgacg tatacattaa
      481 ttcatgaaaa aggggtaatc ccttttgcag tgtgggcttt tttcaattct ttagctattc
      541 caatttttgg ggtacttttt aaaaaattat caagactaaa ggaaattatg gtaaataatc
      601 tctggttagt atactttatg gctatagttc aatgcttttc gattattatt aatttacagg
      661 caatgttcca aatgggaact ttaattggtc tctcttcaag tatgtcaacg ttaatttctt
      721 tatttgctgg ggggatattc ataataagtg tcatcaagaa tggctataaa actgtactat
      781 atagtaatgt tatacagtgg ttgataagta tattagctat tataatactt atttttatag
      841 gtttctcagg taataaagaa gtttctctac gtgcatacac ggacgtaaat tcaatttatt
      901 ggtcacttta tgctggaatt ttattactct ttagcccgtt tgttgatatg caaggatggg
      961 ttagagctat tgaaataaag aaaaatcgcg attttgaagc ctttggattg tcagggatat
     1021 tttttgcaat ttatatgtta ttaattttag tgttatccca attcgaatta tcagttcata
     1081 tgggaataat tttattattt ttagttatta tgatctctac atctacaatt caaccgaatg
     1141 ctcatgcatt aaatgttaat tttaaatacg gttggattgg agcattaata gcttgtcttc
     1201 tttggcctct attaagtaga tttggaatac ttacgttatg gacatatctt gctagtttta
     1261 gagcaattgt agtggcatta gtatttatgt atatgggata cgagaagata agagaattag
     1321 ttatttttaa ataatatgga ggtgcgttat ggtcaaaata gcaa
//
LOCUS       DAVLTT010000131         1357 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVLTT010000131 DAVLTT010000000
VERSION     DAVLTT010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1357
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.131"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            21..860
                     /locus_tag="VYN15_002109"
     CDS             21..860
                     /locus_tag="VYN15_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1453352.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSRVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            967..1242
                     /locus_tag="VYN15_002110"
     CDS             967..1242
                     /locus_tag="VYN15_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV1453353.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
BASE COUNT          450 a          208 c          292 g          407 t
ORIGIN      
        1 aaaatagaaa gattgatact atgacaaaaa ttaagattgt aaccgattca tctgttacta
       61 ttgaacctga actagtaaag caattagata ttacaattgt tccattatct gtaatgattg
      121 ataatgttgt ttattctgat gcggatttga aagaagaagg taaatttctt cagttgatgc
      181 aagaaagtaa gaatcttccg aaaacaagtc agccacctgt aggtgtcttt gctgagattt
      241 ttgaagacct atgcaaagat ggtggccaga ttcttgctat tcatatgtcc catgctcttt
      301 cgggtacggt agaagcagca cgccaaggtg ctagcctatc tactgcagat gtgactgttg
      361 ttgatagttc cttcactgac caagccctga aattccaagt tgttgaggct gcgaagttag
      421 ctcaagaagg taaagatatg gaggcaattt tatctcgtgt agaagaggtt aaaaaccata
      481 cagagcttta tattggtgtt tcaactttgg aaaatcttgt caaaggtgga cgaattagcc
      541 gtgtaactgg cttgttgagc tctcttctca atatccgtgt tgtcatgcaa atgaaagacc
      601 atgaattgca gccaatggtt aaaggtcgtg gaactaaaac atttaaaaaa tggttagatg
      661 agttgataac atcgctttct gaacgtgctg tagcagagat tggaatttca tattctggta
      721 gtgatgattg ggcaaaagag atgaaagaaa gcttacaagc ttatgttgaa aagccaattt
      781 ctgttttgga aacgggttcc attattcaaa ctcacacggg tgagaacgct tgggctattt
      841 tgatacgtta ccactcctaa aaaaataaat aaaatgggaa gaaatagcgt ttttaacttg
      901 acctaaaagg gattttagga tatgattata tttgttaatt agaaattatt tggaggaatc
      961 attaacatgg caaacaaaca agatttgatc gctaaagtag cagaagctac agaattgact
     1021 aagaaagact cagcagcagc agttgaagct gtatttgcag cagtagctga ctatcttgca
     1081 gctggtgaaa aagttcagtt gatcggtttt ggtaactttg aagttcgtga gcgcgcagaa
     1141 cgtaaaggtc gcaacccaca aactggtaaa gaaatgacaa ttgcagcttc taaagtacca
     1201 gcattcaaag ctggtaaagc tcttaaagac gctgttaaat aatcagtctt taaaaagcct
     1261 attgtatcaa gctttctagc ttggtcagta ggctttttaa ttatgaaatc tagtaataaa
     1321 tagagttaaa aagttgaatg ttccgaaaat attgtat
//
LOCUS       DAVLTT010000132         1269 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVLTT010000132 DAVLTT010000000
VERSION     DAVLTT010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1269
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.132"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            358..957
                     /locus_tag="VYN15_002111"
     CDS             358..957
                     /locus_tag="VYN15_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453354.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPIFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            1100..1269
                     /locus_tag="VYN15_002112"
                     /pseudo
     CDS             1100..1269
                     /locus_tag="VYN15_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT          443 a          190 c          252 g          384 t
ORIGIN      
        1 tctttctaat gagttgtttt gtcgcttttc attataggtc atatgggact ttttttctac
       61 acaaaaataa gctccataat atccataggg gatttaccca ctacaaatat tatagagccg
      121 ttaatatttg gagaagagga tggccatctt ctccattttt atgtgcagag ttatagtgac
      181 ttgatgctgg gaaagtacac tgtgactgct aatactcaat gaaaatcaaa gtgcaaacta
      241 ggaagctagc cgcaggctgt acttgagtac gtcaaggtga agctgacgtg gtttgaattt
      301 gattttcgaa gagtataaaa cattcctaga agttgctttg atttccctaa tctatttatg
      361 caaattttat gttattttac tataacagtt gttgctaagc caaataatag tggggaagtt
      421 catttagatg taagcattga agataatcag ggaggtagtg ggcataattt cagttctgtt
      481 tcaagtagct cacaaacagc taaatatgaa gaaactggtt ataataacaa ttcatcatta
      541 tatataacga ttgataaaac gtctgatgca acagctcttt tgaaattaaa gttgaataat
      601 gttgataatc aacctgctac tgaagttcct agttcaggaa ttactgtaaa attaaatgct
      661 aaagataatg ctggaaactg gacaagtgct tcgaataaaa aagaaataac agtaaaaatt
      721 gtttctgcta aaccgacata tccagacaaa atcttagtga aaaatcctga taatataaaa
      781 gatacagaaa aaaatgccat tattgaaaaa ttgaaagagg caaataaaaa tcatccagca
      841 ggagctccaa tctttgctaa aggtgaagga gagcatgcaa atgatattgt agcaacttat
      901 tcagatggta caacttatta tgtaccgtta aatgatgtga caaaatatgc gaggtagtgg
      961 ttgtaccact cacttattca cctccccgtg atttgtagta gtgataggct ttctaactat
     1021 tattataaaa caaaataaag agcacaacac tttttcattc tgtgttgtgc cttgagtgaa
     1081 acgaaaggaa tgaattataa atatgaaaag tatagtcact agcatagatg agcgcttgcg
     1141 tactcgccta cgagtgatta tctggaagca atggaagaag aaatcgagac gattatgggg
     1201 attgcttaag ttaggggttc ctaaatggat agcagataag gtatctggct ggggcgacca
     1261 ctatcaatt
//
LOCUS       DAVLTT010000133         1249 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVLTT010000133 DAVLTT010000000
VERSION     DAVLTT010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1249
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.133"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            219..695
                     /locus_tag="VYN15_002113"
                     /pseudo
     CDS             219..695
                     /locus_tag="VYN15_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            733..1035
                     /locus_tag="VYN15_002114"
     CDS             733..1035
                     /locus_tag="VYN15_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1453355.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            1043..>1249
                     /locus_tag="VYN15_002115"
     CDS             1043..>1249
                     /locus_tag="VYN15_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1453356.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYE"
BASE COUNT          426 a          214 c          238 g          371 t
ORIGIN      
        1 aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtattag aacagaaaaa
       61 tgcttggagt atttgtttgt gtgtttattt ttatataaca aactataaac aaaacaaaaa
      121 tataaaaaag agacaaaaaa gaacagaaag taattaacaa cgatttcata tagtgttata
      181 cttatagcat aaagttaatg gaaagaaggg aaaaccttat ggtattagat tatttctttg
      241 acaaaaacct tgtgttttgc ttagaagcgg ataatcaaga ataactcttt gatcaggtag
      301 caagcttgtt ggaggaacga gaaattgtaa ctccaactta tcgtgaagcc ttgatcacgc
      361 gtgaaaagtc atttccaact ggtttagata tggaatttct aggaaaggac ttgccaaatg
      421 tagcgattcc tcacacagat attgttcata atttggctga aaaagttgtg gtcgttcgat
      481 tagagaaacc ggtgactttc cataatatga ttgcgccaga taaggaagta gaagtatcct
      541 tgctcttctt tatcattaat aattcaagtt caagtcaaac gaacattctt gctcagttaa
      601 tggacttctt cacaggaaat ggtcatcttg aagacctatc aaaaatttct gaaccagaag
      661 ccctttatgc ttacattgct gaagcaaccg cttaatcttg tctattaaaa aataaaatcg
      721 gaggaaatcc aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac
      781 caaattaaaa gtgctctaga agaagaactt tcaaaccgtg gttacgatgt tcactgtgat
      841 gcagttatgg tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca
      901 atcgctgcaa cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc
      961 ttattccgta tcccagcaat gagcgttcca gtatttgaca atattagact tcctgcgaaa
     1021 caaaacatgg tatagtagtt ctatgaatga tgaagcaagt aaacaactaa ctgatgcacg
     1081 atttaagcgt cttgttggtg ttcagcgcac gacttttgaa gagatgttag ctgtattaaa
     1141 aacagcttat caacttaaac acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga
     1201 ccttcttatg gccactcttc aatatgtgcg agaatatcga acttatgaa
//
LOCUS       DAVLTT010000134         1180 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVLTT010000134 DAVLTT010000000
VERSION     DAVLTT010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1180
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.134"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            239..>1180
                     /locus_tag="VYN15_002116"
     CDS             239..>1180
                     /locus_tag="VYN15_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV1453357.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFL"
BASE COUNT          413 a          209 c          244 g          314 t
ORIGIN      
        1 agccacctta ccttagtcaa gaattagatg tttcactatg tttgagtaag ttgatgattt
       61 catttgataa caggtttgaa actgttaggc taggtggcca aggctaatca tagccttggt
      121 ttagctgaaa aaacaggttc aagggttcct gttgtcaaat gaaatgtgat ttaaggtata
      181 agaaaacacc tctgtgctat acttgttgtt caccacaaac acaaggaaag gcacagagat
      241 gcaagaacat tataccccaa aagggaaaca tttgacaata gataaccgtc gcttgattga
      301 gcggtggaag aatgaaaata agtccaatcg tgaaattgca ggcttgttag gaaaggcgcc
      361 tcaaacgatt cataatgaag tcaaaagagg tacaacttta caacaagtga gaaaagggct
      421 atacaaaaag gtctattctg ccgattacgc acaaactgtt taccaattca atcgaaaacg
      481 gtcggtgaaa aagttaattt taacaaagga aatcagagag aagatcttac actatcataa
      541 gcaaaaattt tcgcctgaaa tgatggttaa caagaagcaa gtgaaagttg gtatttcaac
      601 catctactac tggtttcata atggtcattt aggattgacg aaggccgaca tgctttatcc
      661 cagaaaaagg aaaggtgtca agaagcaagc tagtccgaac tttaagccgg caggtaaatc
      721 tatcgaagaa cgtcctgacg ttattaatct tcgcttggaa aatggtcatt atgaaattga
      781 taccgtccta ctgactaaga taaaaaatta ttgcctgtta gtcttaaccg accggcggag
      841 cagacaccaa attataaggt taattccaaa taaaactgct gaatctgtca atcaggcgct
      901 tacgttacta ttaggggagc atcgtattct gtccattact gcagataatg gttcggagtt
      961 caaacgattg tctgaggtat ttcctgagga acatatctac tacgcacatg cttactcttc
     1021 atgggagaga ggttcaaatg aaaatcataa tcgattaatt cggagatggt tacctaaagg
     1081 aaccaagaaa acgactccga aagaagtagc ttttatcgaa aattggatta acaactaccc
     1141 taaaaaatgc ttggactaca agtcgccaag tgaatttctt
//
LOCUS       DAVLTT010000135         1149 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVLTT010000135 DAVLTT010000000
VERSION     DAVLTT010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1149
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.135"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(250..879)
                     /locus_tag="VYN15_002117"
     CDS             complement(250..879)
                     /locus_tag="VYN15_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1453358.1"
                     /translation="MFILGSGDQGLAVLSIYEGEVEGLVDIFEEGRFIGCKILDKTVL
                     GGLKWFESLLLTLDRKPRAIVAFGDNFKREEIFCSYKNKVEYINVICNSARIFKHSFL
                     GKGNFIGTNVTIQALVEIGDNNIINSGSIVSCNCKIGNNVNISPGVILSGNVKIDDNV
                     FIGAGATIRDAVSIGFGAIIGAGATVIHNVPENAVVVGTPGKIIKYRSV"
     gene            complement(915..>1149)
                     /locus_tag="VYN15_002118"
     CDS             complement(915..>1149)
                     /locus_tag="VYN15_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HEV1453359.1"
                     /translation="TIPPKEGELLSVNLYKDSWVEKVNFDETSIGRRYSGGDYSASAL
                     IAYLISGTDEDDLKNKILHIIEWQDKNTIYKEK"
BASE COUNT          400 a          241 c          120 g          388 t
ORIGIN      
        1 aacaatactc ataaagtcaa ataagataat cctaaaaatt cacaagttga aaagatttca
       61 atttgttgag ccaactatcc caaaatactt ctgtcataat tacagtgtcg aaatgtatac
      121 tttaagaatt cttacattaa tcattagatc agttgaaacc taggagctaa cactaatatc
      181 taactaattc cttatgagat tactgacatg cgatgaaact taagttatat ggcaatgaag
      241 agtttctctt caaactgatc tatattttat tattttccct ggtgttccta ctaccacagc
      301 attttccggt acgttatgta ttacggtagc acctgcacca attatagcac caaagccaat
      361 gcttaccgca tctctaattg ttgctcctgc accaataaaa acgttatcat caattttaac
      421 atttccagat aatataacac ctggggaaat atttacatta ttaccaattt tacaattaca
      481 tgaaacaata ctaccagaat ttataatatt gttgtcaccg atttctacaa gtgcttgaat
      541 agtcacattg gtaccaataa aatttccttt tcctaaaaaa gaatgtttaa aaattctcgc
      601 ggaattacat ataacattaa tgtactccac cttattttta tatgaacaaa atatttcttc
      661 gcgcttaaaa ttatcaccaa atgcaacaat tgctctaggc ttcctatcaa gtgttaagag
      721 taaactttca aaccatttta atccccctaa aacagtttta tctaagattt tgcaaccaat
      781 aaagcgacct tcctcaaaaa tatctaccaa tccctcaact tcaccttcat aaattgacaa
      841 taccgccaat ccttgatctc ctgaacctag tataaacata tcctttaccc acaattttta
      901 aaacaaactt atgattattt ctctttatat attgtatttt tatcttgcca ctcaataata
      961 tgtaaaattt tattcttcaa atcgtcttca tcagttccac taatcaaata tgctataaga
     1021 gcagaagcgc tataatcacc gccactatat cttctcccaa tagaggtctc atcaaaattc
     1081 actttctcaa cccatgaatc tttatacaaa ttaacagata gtaattctcc ttctttagga
     1141 ggaattgtt
//
LOCUS       DAVLTT010000136         1110 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVLTT010000136 DAVLTT010000000
VERSION     DAVLTT010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1110
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.136"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..389
                     /locus_tag="VYN15_002119"
     CDS             <1..389
                     /locus_tag="VYN15_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="diadenosine tetraphosphate hydrolase"
                     /protein_id="HEV1453360.1"
                     /translation="SQFFEGYCILFSKEPYPSLSDMPMEFRKEFLMEMSILGDAMLEV
                     LNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRKTVVHRYDSSVFSNPEFEFTIEKH
                     GPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            476..882
                     /gene="cdd"
                     /locus_tag="VYN15_002120"
                     /pseudo
     CDS             476..882
                     /gene="cdd"
                     /locus_tag="VYN15_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            895..>1110
                     /locus_tag="VYN15_002121"
     CDS             895..>1110
                     /locus_tag="VYN15_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1453361.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDIPKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDV"
BASE COUNT          392 a          134 c          201 g          383 t
ORIGIN      
        1 attctcagtt ttttgaagga tattgtattc ttttttcaaa agaaccctat ccttctttat
       61 ctgatatgcc aatggaattt agaaaagaat ttttaatgga aatgagtata ttaggtgatg
      121 cgatgcttga agtgttaaat gcctatagaa ttaattatga tatcttagga aattcaacac
      181 ctgtacttca tgctcattta tttccgagat acatgtggga agaggaagag agaagaaaaa
      241 ctgtagttca tagatatgat tcttcagttt ttagcaatcc tgagtttgaa tttactatag
      301 aaaagcatgg accaattatt aaaaaactga ggtctgctat tgatagacat tatagagagt
      361 atcaacaatt attagatgat tcaaactgaa ctccacattt tcgattagat ttaatacctt
      421 gtatattaca actaggttgt ggatgatata attttttgaa aaatatattt taggaatgac
      481 ttataaagca attatatcag aggctattaa atcaatggcc aaagcttatg ctccttattc
      541 tgattttaag gttggagctg cgttagtaac tgaagataaa aaattttttc tggatgtaat
      601 atagaaaatg ctgctttttc tcctacttgc tgtgcagaac gagtatcttt ttataaagct
      661 gtatttaaag gagaacgttc gttttcaaga atatgtattg taggtggaaa aaatggtatc
      721 ttatcatctt ttatagcacc ttgcggagtg tgtcgccagg taatgataga attttgtaat
      781 cctgattcat ttgaagttat attggctagt gatgttgata cttataaagt atataaactt
      841 aaagaactac taccagttag ttttaatcaa gaaaatttat aacaggaggg aactatggaa
      901 ttagttgaat ttaaaaatgg acatgttaat acggttcatg agcatatcgc aataacgaaa
      961 gtaaaagagt ttctaaataa tcatgatata ccaaaagata aaggtggcat acataaaatt
     1021 tctactgatt tcttttacaa tataattgat atggaaacta caactgaaga gaatagaccg
     1081 tgggaaagtc ataaggaata ttatgatgtc
//
LOCUS       DAVLTT010000137         1026 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVLTT010000137 DAVLTT010000000
VERSION     DAVLTT010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1026
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.137"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..574
                     /locus_tag="VYN15_002122"
     CDS             <1..574
                     /locus_tag="VYN15_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1453362.1"
                     /translation="KIPSGLYKIDTGKVLFYGININQIDKKILSQNLGVVPQDSFLLN
                     RSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIA
                     LARALINNPSIVILDEATSALDTINEERITKYIKSQGCTQIIVAHRLSTIKDADIIVV
                     MKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
     gene            587..757
                     /locus_tag="VYN15_002123"
     CDS             587..757
                     /locus_tag="VYN15_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453363.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
BASE COUNT          376 a          127 c          193 g          330 t
ORIGIN      
        1 aaaaatacca tcaggattat ataagattga tacaggaaaa gttttatttt atggtataaa
       61 tattaatcaa atagataaaa aaatattaag tcaaaattta ggagtagttc cacaggattc
      121 gtttttattg aacagaagta ttcttgataa cataacttta aagcacgaag ttacttcaca
      181 aaagatagag gaagtttgta aagcagttca aatctatgat gaaatcatgg ctatgccgat
      241 gaaatttaat actatcatct cagagatggg ttcaaatatt tcaggtggtc aaagacaacg
      301 gatagcactg gcacgtgcat taataaataa tcctagtatt gtaattttag atgaagcaac
      361 tagtgcttta gacactatta atgaggaaag aataacaaag tatataaaaa gtcagggctg
      421 tactcaaata attgtagctc atagattgtc aacgattaag gatgcggata ttattgttgt
      481 aatgaaaggt ggtaagattg ttgagtcagg aaatcataag tacttaatgg atcttggtgg
      541 agagtactac agcttatata caaaaaggaa atgaggtgta aagaaaatga agaaagaaaa
      601 tgaatatgta attttaacaa cagcctcact aggggtgatg attggaatag tgtttgcaat
      661 ttttttagat tttccagttg aatatggtat ttctttagga ttgttgaatg gaatagtatt
      721 gggttcgctg attgtttaca aaaacaataa gaattaagca taattttttg ctgtacacta
      781 aggagtagag atggctatag ttgaaattat aaatctaaca aaaagcttta aagatattga
      841 agttattcat aacacttaaa taatagagca actacagtag tagcttaaaa acatgattaa
      901 atcgctattc ttaggagtag cgttttttct ttttgtttaa tactctttga aaatctcttc
      961 aaaccacgtc agctttgcct tgccgtactc aagtacagcc tgcgactcgc ttcctagttt
     1021 gctctt
//
LOCUS       DAVLTT010000138          879 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVLTT010000138 DAVLTT010000000
VERSION     DAVLTT010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..879
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.138"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(<1..211)
                     /locus_tag="VYN15_002124"
     CDS             complement(<1..211)
                     /locus_tag="VYN15_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEV1453364.1"
                     /translation="MKQIILSTGSTSSLGLDNLATFEKFTKNKVYDYEIFFQSRLELT
                     ASEIKKVKEYCSQKGVSVNSIHPFME"
     gene            complement(221..847)
                     /locus_tag="VYN15_002125"
     CDS             complement(221..847)
                     /locus_tag="VYN15_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV1453365.1"
                     /translation="MKVGDKVKKALIITAHPDDAEISMGGHIINMVNNGYYVKLLVLS
                     VPEDKTRILEAGKSAEFLGIELKIVGDKSQVSQFSSSELVSIIDNEIEEFDPSYVFTH
                     WENDAHKDHRIIFKAVQSSSRCHSFTFLSFSPPNIYVSNALQFVPNIFVEINIEKKLR
                     AIEFHRSQVNQKSYPIDGPKVQSVLFGKHIGVDYAEGFILIRHIDRKC"
BASE COUNT          295 a          161 c          105 g          318 t
ORIGIN      
        1 cctccataaa aggatgtata gaattaacac ttactccctt ttggctacaa tattctttta
       61 ctttttttat ttcagaagca gtcaattcca atctagattg gaaaaaaatt tcataatcat
      121 atactttatt tttagtaaat ttttcaaaag ttgctaaatt atctaaccct agagaactag
      181 tgcttccagt ggataatatt atttgtttca tacttcctca ttaacacttt ctatctatgt
      241 gtctaatcag tataaatccc tctgcataat ctactcctat atgtttacca aataagacag
      301 attgaacttt aggtccatct attggatatg acttttgatt cacttgactt ctatggaatt
      361 caatagccct caactttttc tcaatattga tttctacaaa aatatttgga acaaactgca
      421 aagcattgct aacatatata ttaggaggag aaaacgatag aaaagtaaac gaatgacacc
      481 tactagagga ctgcacagct ttaaatatta ttcgatgatc tttatgggca tcattttccc
      541 aatgtgtaaa aacataagat ggatcaaatt cctcaatttc gttatcaata attgaaacta
      601 attcacttga actaaactga gaaacttgag atttgtcacc aactattttt aattctatcc
      661 ctagaaattc tgcagacttt cctgcttcta aaatcctcgt tttatcttct ggaactgata
      721 aaaccagtag tttgacataa taaccattat taaccatatt aattatatgt ccacccatag
      781 aaatttcagc atcatctgga tgggcagtaa ttattaatgc ttttttcact ttatctccta
      841 ctttcattat attggaagtt cccaatttca aaataatga
//
LOCUS       DAVLTT010000139          858 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVLTT010000139 DAVLTT010000000
VERSION     DAVLTT010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..858
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.139"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..>858
                     /locus_tag="VYN15_002126"
     CDS             <1..>858
                     /locus_tag="VYN15_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV1453366.1"
                     /translation="CINTERNGVPISRPLTTVLDNITTVSEQLVIVESTISPNWIDTI
                     IRPKLNDLQYLTVAPRRDWFLETGLNLKTLPRVIGTLGSNYRMEVLKLYEMLSYVVIE
                     VTDAYHACLVKAVENSIRYINVVFANEMMRAFPRYNMAEIFDAASTKWNIPYYHPSIG
                     IGGYCLPLAPKYILDAVNDSEELPMLRESVKSDLKQSDFITDLIKSYNCQKVVVLGLS
                     YAPETKIWKNSPAVSLIYSLLRNGIEVKINDPYFSSEEIQEITTVQSFSLNSESLQEF
                     DILVIATSH"
BASE COUNT          288 a          116 c          160 g          294 t
ORIGIN      
        1 tctgtattaa tactgaaaga aatggagtac ctattagtag accattaact actgtattag
       61 ataatataac aacagtatct gaacaactag ttattgttga aagtacaatt tctccaaatt
      121 ggattgatac aattataaga ccaaagttga atgatttgca atatctaaca gttgctccta
      181 ggagagactg gtttttagag actggattaa atttaaaaac acttcctcga gttattggta
      241 cattgggatc aaattatcgt atggaggttt tgaaattata tgaaatgctt tcttatgttg
      301 tgattgaggt aactgatgca tatcacgctt gtttagtaaa ggcggttgaa aattctatac
      361 gctatattaa tgttgtattt gctaatgaaa tgatgagagc atttccaaga tataatatgg
      421 ctgaaatttt tgatgctgct tcaactaagt ggaatattcc ttattatcat ccgtcaattg
      481 gaattggagg gtactgtctt ccgttagctc ctaaatatat tttggatgca gtcaatgata
      541 gtgaggagtt acctatgctg agggagtcag ttaaatctga tttaaagcag tctgacttta
      601 ttactgactt aatcaaaagc tataactgtc aaaaagtagt agtattaggt ctaagttatg
      661 ctccggagac taaaatttgg aagaattccc cagctgttag tttaatctat tctttgttaa
      721 gaaatggaat agaagtgaaa ataaatgatc catatttctc tagtgaagaa attcaagaaa
      781 taacgactgt tcaatctttc agtttaaata gtgagtcact acaagaattt gatatactgg
      841 taattgctac ctcacata
//
LOCUS       DAVLTT010000140          845 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVLTT010000140 DAVLTT010000000
VERSION     DAVLTT010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..845
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.140"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(<1..>845)
                     /locus_tag="VYN15_002127"
     CDS             complement(<1..>845)
                     /locus_tag="VYN15_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEV1453367.1"
                     /translation="ISDTPLVFFSSGTTGVPKPVMINKLAFTELINLMIAQLEISSDD
                     VLYLPSHIAFIQSLWAAMIVIFSGGRVIFKDRITYKTFFKELQLNDATITVMVPTTMN
                     KLVNLYTNTLQGCKKLRCIIVGGEIINKDSANFLLNKLKNTNIANAYGMVETTAVCCL
                     QYGRDLKNINSVGTTLPGVEVEVKNIDDDGNGDIWIKTNRFMSGYYPSKYTGEWLYTG
                     DRGYKNKEGLLFVTGRESLSINKGGIKINPIEIEQIILQLPDIQLCKVEKISDNIYGE
                     NYILEV"
BASE COUNT          269 a          164 c          104 g          308 t
ORIGIN      
        1 acttctaata tataattttc tccgtaaata ttatcactaa ttttttcaac tttacaaagt
       61 tgaatatctg gcaattgaag aataatctgt tcaatttcaa taggattaat ttttatacct
      121 cccttattaa ttgacaaact ttcacggcct gttacaaata aaagtccttc cttattttta
      181 tatcctctat ctcctgtata taaccattca ccagtgtatt tactcgggta atatccgctc
      241 ataaagcgat ttgtctttat ccagatatcg ccattaccat catcatctat attctttact
      301 tcaacttcaa cccccggtag agttgtacca acagagttaa tattttttaa atcacgtcca
      361 tattgtagac aacaaactgc ggttgtctct accataccat atgcatttgc tatgtttgtg
      421 tttttcaatt tatttaataa aaagtttgca ctatccttat ttataatctc tccacctaca
      481 ataatacatc ttaatttttt acacccttgg agagtatttg tatataaatt aacaagttta
      541 ttcatcgtag taggtaccat aaccgttatt gttgcatcgt ttagttgaag ttccttaaaa
      601 aatgttttat atgtaatcct atctttaaaa attactcttc cccccgaaaa aattactatc
      661 atcgcagccc agagagattg aatgaaagca atgtgggagg ggagatacaa cacatcatca
      721 ctagatattt ctaactgtgc tatcatcaga ttaattaatt ctgtaaaagc taatttatta
      781 atcattaccg gcttaggcac tcctgttgta cctgatgaaa aaaacactaa aggagtgtcc
      841 gaaat
//
LOCUS       DAVLTT010000141          773 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.141, whole genome shotgun sequence.
ACCESSION   DAVLTT010000141 DAVLTT010000000
VERSION     DAVLTT010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..773
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.141"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(<1..>773)
                     /locus_tag="VYN15_002128"
     CDS             complement(<1..>773)
                     /locus_tag="VYN15_002128"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1453368.1"
                     /translation="EALVLAEADALVLVDADVLAEVDALVDADVLAEAEALVLAEAEA
                     LVEADSDALVDAEAEALVEADSDALVDAEAEALVDADSDALVDAEADALVDAEADALV
                     DAEADALVDAEADALVLADSDALVDAEADALVDAEADALVDAEAEALVLAEAEALVLA
                     EAEALVDAEADALVLAEAEALVDAEADALVDAEADALVDADSDALVDAEADALVDAEA
                     EALVDAEAEALVDAEAEALVDADSEAEILAEADALVDAE"
BASE COUNT          192 a          242 c          185 g          154 t
ORIGIN      
        1 ttccgcatca acaagtgcgt cagcctcagc aagtatctca gcttctgaat cggcatcaac
       61 gagtgcctcg gcctcagcgt caacgagtgc ctcagcctca gcatcgacaa gcgcttcagc
      121 ttcagcgtca acaagtgcat cggcttcagc gtcaacgagt gcgtctgagt cagcatcaac
      181 gagtgcgtca gcctcagcat caacaagtgc gtcagcttca gcatcaacca gtgcttcagc
      241 ctcagcaagt actagtgcat cagcttcagc atcaacgagt gcttcggctt cagcaagcac
      301 cagtgcttcg gcttcagcaa gtactagcgc ctcagcctca gcatcaacga gtgcgtcagc
      361 ctcagcatca acgagtgcat cggcttcagc gtcaaccagt gcatcagagt cagcaagtac
      421 cagtgcgtca gcttcagcat caacgagtgc gtcagcttca gcgtcaacga gtgcgtcagc
      481 ttcagcgtca acgagtgcgt cagcttcagc gtcaacgagt gcgtctgagt cagcatcaac
      541 aagtgcttca gcttcagcat caaccagtgc atcagagtca gcctcaacga gtgcttcggc
      601 ttcagcgtca accagtgcat cagagtcagc ctcaacgagt gcttcggctt cagcaagcac
      661 cagtgcttcg gcttcagcaa gcacatcagc atcaacaagc gcgtcgacct cagcaagtac
      721 atcggcatca acaagcacca gtgcgtcggc ttcagcaagt actagcgcct cag
//
LOCUS       DAVLTT010000142          727 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.142, whole genome shotgun sequence.
ACCESSION   DAVLTT010000142 DAVLTT010000000
VERSION     DAVLTT010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..727
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.142"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            1..727
                     /locus_tag="VYN15_002129"
                     /pseudo
     CDS             1..727
                     /locus_tag="VYN15_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          222 a          134 c          157 g          214 t
ORIGIN      
        1 cgccttcaaa tcgttctatt tcgtctgatg ggcaaatctt ataaagagat tatagagctt
       61 ttagactgta atcaaacaac gatttggcga aatgtaaaaa aatatgagga gttcggactc
      121 gactctctcc ttcaagaaac acgtggtggt cgtaaccatg catatatgac agttgaggaa
      181 gagaaagcct ttcttgcccg tcatttgaag gctacagagg caggagaatt tgttacaatt
      241 gatgccttat ttcaggctta taaaaaggag ttaggtcgtt cctacacacg tgatgccttc
      301 tatcaactgt tgaagcgcca tggttggcga aatattatgc cacgtccaga acatcctaag
      361 aaagcagacg ctcaaaccat tgtcgcgtct aaaaataaaa tctcaattca agaagaaaag
      421 aaagcgcttt aaaaccagta gacgttttca taaggttcgc ttgatgtacc aagatgaggc
      481 tggcttcggt agaatcagta aactgggatc ttgttggtct ccaataggag taggtccaca
      541 tgtccatagt cactatatac gagaatttca ctattgttat ggagctgttg atgcccatac
      601 aggcgaatca tttttcttaa tagctggtgg atgtaatact gagtggatga acgtcttttt
      661 agaagagctt tcacaagctt atccagatga ttatttttta ctcgttatgg acaatgctat
      721 atggcat
//
LOCUS       DAVLTT010000143          679 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.143, whole genome shotgun sequence.
ACCESSION   DAVLTT010000143 DAVLTT010000000
VERSION     DAVLTT010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..679
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.143"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..>679
                     /locus_tag="VYN15_002130"
     CDS             <1..>679
                     /locus_tag="VYN15_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1453369.1"
                     /translation="FLKLDKNELNALSLRDKKLSKLKVPYLKEGGEYQIKNLSYKFTD
                     DECLSLKDISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERL
                     KNSSLVMQDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGG
                     QKQRLAIASVMCKNSPFIFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEF
                     LNEVADEI"
BASE COUNT          274 a           73 c          123 g          209 t
ORIGIN      
        1 atttttaaag ctagataaaa atgaattaaa tgctttaagt ttaagagata aaaaattaag
       61 taaattaaaa gttccttatt taaaagaagg tggagagtat cagataaaaa atcttagcta
      121 caaatttact gatgatgagt gtttaagctt aaaagatatt tcattcaagc ttgggaaaat
      181 ttatggcata ataggatcca acggacgagg aaaatcaacg cttttaagat gtttaatagg
      241 tcttgagaaa aaatcaaaag aagaaattta ttttaaggga gagaagctat ctaaaaaaga
      301 aagactcaaa aactcttcac ttgttatgca agatgtaaat catcaattat tcacagatga
      361 agtattcaac gagcttagat taggagtaaa gaattttgat gaagaaaagg cgaaaatcat
      421 tttaaaagat ttaggcctgg acgaatttat tgaaaggcat ccgatgagtt tatcaggagg
      481 gcaaaagcaa aggcttgcaa tagcatctgt tatgtgcaag aattctccat ttatcttttt
      541 tgacgaacct tcaagtggta tggattattc caatatgata aaaatatctg aactgattaa
      601 taagtataaa accatggata aaataatttt tattgtttcc catgatatag aatttttaaa
      661 tgaagtggca gatgaaatt
//
LOCUS       DAVLTT010000144          587 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.144, whole genome shotgun sequence.
ACCESSION   DAVLTT010000144 DAVLTT010000000
VERSION     DAVLTT010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.144"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            complement(<1..>587)
                     /locus_tag="VYN15_002131"
     CDS             complement(<1..>587)
                     /locus_tag="VYN15_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chordopoxvirus G3 family protein"
                     /protein_id="HEV1453370.1"
                     /translation="ALVDADSEALVDAEAEALVDAEAEALVDAETEALVDADSDAEVL
                     AEAEALVDADSDALVDADSDAEVLAEADALVLAEAEALVLAEAEALVDAEADALVLAE
                     AEALVDAEAEALVDAEADALVDADSEAEVLAEAEALVLAEADALVDADSEALVDAEAD
                     ALVDAEAEALVDAEAEALVDAEAEALVDADSDALV"
BASE COUNT          147 a          197 c          130 g          113 t
ORIGIN      
        1 tcaacaagtg cgtctgaatc ggcatcaacg agtgcctcag cctcagcgtc aaccagtgcc
       61 tcagcctcag catcgacaag cgcttcagct tcagcgtcaa caagtgcatc ggcttcagcg
      121 tcaacgagtg cctctgaatc cgcatcaaca agtgcatcgg cctcagcaag taccagtgct
      181 tcagcttcag caagtacctc agcttctgaa tcggcatcaa cgagtgcatc agcttcagca
      241 tcaacgagtg cctcggcctc agcgtcaacc agtgcctcag cctcagcaag tacaagtgcg
      301 tccgcttcag cgtcaaccag cgcctcagcc tcagcaagca caagcgcctc agcttcagca
      361 agtaccagtg cgtcagcctc agcaagcacc tcagcatctg aatcagcgtc aaccagtgcg
      421 tctgagtcag catcaacaag tgcctcggcc tcagcaagca cctcagcgtc tgaatcggca
      481 tcaacgagtg cttcagtctc agcatcaacg agtgcttcag cttcagcatc aacaagtgcc
      541 tcggcttccg catcaacgag tgcctctgaa tccgcatcaa caagtgc
//
LOCUS       DAVLTT010000145          464 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.145, whole genome shotgun sequence.
ACCESSION   DAVLTT010000145 DAVLTT010000000
VERSION     DAVLTT010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.145"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..>464
                     /locus_tag="VYN15_002132"
     CDS             <1..>464
                     /locus_tag="VYN15_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1453371.1"
                     /translation="PIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDI
                     TSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKG
                     AEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEG"
BASE COUNT          156 a           97 c          102 g          109 t
ORIGIN      
        1 ccgattcgtc atccagaacg tttaggaaaa ccaaatgcgc aaattaccta cactgatgat
       61 gagattcaag tagccaagtt ggcaggcaag tacacaacag aagacggtta tatctttgat
      121 cctcgtgata taaccagtga tgagggggat gcctatgtaa ctccacatat gacccatagc
      181 cactggatta aaaaagatag tttgtctgaa gctgagagag cggcagccca ggcttatgct
      241 aaagagaaag gtttgacccc tccttcgaca gaccatcagg attcaggaaa tactgaggca
      301 aaaggagcag aagctatcta caaccgcgtg aaagcagcta agaaggtgcc acttgatcgt
      361 atgccttaca atcttcaata tactgtagaa gtcaaaaacg gtagtttaat catacctcat
      421 tatgaccatt accataacat caaatttgag tggtttgacg aagg
//
LOCUS       DAVLTT010000146          377 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.146, whole genome shotgun sequence.
ACCESSION   DAVLTT010000146 DAVLTT010000000
VERSION     DAVLTT010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.146"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
BASE COUNT          148 a           56 c           50 g          123 t
ORIGIN      
        1 agaaatgata taccatttta aattactttt tatataaata agtatatttt taattcccct
       61 atccttcaat aatcggtata aaagatactg actcatacct tgataccaaa taaaattcgg
      121 tatttcaata agagcatgag gtaatattcc ttttattgta gctactattc caatcatctg
      181 accagatata cccaattgta ttcctaaaga tagcaaatca aaaagttgca ataagggcga
      241 aatcggaaaa cagaatagat atagcaaaaa atttgtagaa tttgcctgta aaactgtcaa
      301 tgtaaattgt aattccagtt tcggaggtat agtagcaaaa gtctcatttt ttaatataaa
      361 gcttaaaagt aaaccta
//
LOCUS       DAVLTT010000147          354 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00066629
            SAMN33607350-rid17942143.denovo.147, whole genome shotgun sequence.
ACCESSION   DAVLTT010000147 DAVLTT010000000
VERSION     DAVLTT010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607350
            Sequence Read Archive: SRR23725638
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721515.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721515.1
            Genome Coverage       :: 108x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:27:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,086
            Genes (coding)                    :: 1,954
            CDSs (with protein)               :: 1,954
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 53 of 132
            Pseudo Genes (incomplete)         :: 60 of 132
            Pseudo Genes (internal stop)      :: 46 of 132
            Pseudo Genes (multiple problems)  :: 22 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607350-rid17942143.denovo.147"
                     /strain="AUSMDU00066629"
                     /serotype="35F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST446"
     gene            <1..>354
                     /locus_tag="VYN15_002133"
     CDS             <1..>354
                     /locus_tag="VYN15_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1453372.1"
                     /translation="RGVAVPHGNHYHFIPYEQMSELEERIARIIPLRYRSNHWVPDSR
                     PEQPSPQPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDL
                     SAETAAGIDSKLAKQE"
BASE COUNT          112 a           85 c           72 g           85 t
ORIGIN      
        1 agaggtgtag ctgtccctca tggtaaccat taccacttta tcccttatga acaaatgtct
       61 gaattggaag aacgaattgc tcgtattatt ccccttcgtt atcgttcaaa ccattgggta
      121 ccagattcaa gaccagaaca accaagtcca caacctagtc caagtccgca acctgcacca
      181 aatcctcaac cagctccaag caatccaatt gatgagaaat tggtcaaaga agctgttcga
      241 aaagtaggcg atggttatgt ctttgaggag aatggagttt ctcgttatat cccagccaag
      301 gatctttcag cagaaacagc agcaggcatt gatagcaaac tggccaagca ggaa
//
